Skip to content

Functional analysis

Last updated: November 28, 2023

Section Overview

🕰 Time Estimation: 120 minutes

💬 Learning Objectives:

  1. Determine how functions are attributed to genes using Gene Ontology terms
  2. Describe the theory of how functional enrichment tools yield statistically enriched functions or interactions
  3. Discuss functional analysis using over-representation analysis, functional class scoring, and pathway topology methods
  4. Identify popular functional analysis tools for over-representation analysis

The output of RNA-seq differential expression analysis is a list of significant differentially expressed genes (DEGs). To gain greater biological insight on the differentially expressed genes there are various analyses that can be done:

  • determine whether there is enrichment of known biological functions, interactions, or pathways
  • identify genes' involvement in novel pathways or networks by grouping genes together based on similar trends
  • use global changes in gene expression by visualizing all genes being significantly up- or down-regulated in the context of external interaction data

Generally for any differential expression analysis, it is useful to interpret the resulting gene lists using freely available web- and R-based tools. While tools for functional analysis span a wide variety of techniques, they can loosely be categorized into three main types: over-representation analysis, functional class scoring, and pathway topology. See more here.

The goal of functional analysis is to provide biological insight, so it's necessary to analyze our results in the context of our experimental hypothesis: What is the function of the genes dysregulated by Vampirium?. Therefore, based on the authors' hypothesis and observations, we may expect the enrichment of processes/pathways related to blood production and behaviour control, which we would need to validate experimentally.

Note

All tools described below are great tools to validate experimental results and to make hypotheses. These tools suggest genes/pathways that may be involved with your condition of interest; however, you should NOT use these tools to make conclusions about the pathways involved in your experimental process. You will need to perform experimental validation of any suggested pathways.

Over-representation analysis

There are a plethora of functional enrichment tools that perform some type of "over-representation" analysis by querying databases containing information about gene function and interactions.

These databases typically categorize genes into groups (gene sets) based on shared function, or involvement in a pathway, or presence in a specific cellular location, or other categorizations, e.g. functional pathways, etc. Essentially, known genes are binned into categories that have been consistently named (controlled vocabulary) based on how the gene has been annotated functionally. These categories are independent of any organism, however each organism has distinct categorizations available.

To determine whether any categories are over-represented, you can determine the probability of having the observed proportion of genes associated with a specific category in your gene list based on the proportion of genes associated with the same category in the background set (gene categorizations for the appropriate organism).

The statistical test that will determine whether something is actually over-represented is the Hypergeometric test.

Hypergeometric testing

Using the example of the first functional category above, hypergeometric distribution is a probability distribution that describes the probability of 25 genes (k) being associated with "Functional category 1", for all genes in our gene list (n=1000), from a population of all of the genes in entire genome (N=23,000) which contains 35 genes (K) associated with "Functional category 1" [4].

The calculation of probability of k successes follows the formula:

\(\(Pr(X = k) = \frac{\binom{K}{k} \binom{N - K}{n-k}}{\binom{N}{n}}\)\)

This test will result in an adjusted p-value (after multiple test correction) for each category tested.

Gene Ontology project

One of the most widely-used categorizations is the Gene Ontology (GO) established by the Gene Ontology project.

Quote

"The Gene Ontology project is a collaborative effort to address the need for consistent descriptions of gene products across databases".

The Gene Ontology Consortium maintains the GO terms, and these GO terms are incorporated into gene annotations in many of the popular repositories for animal, plant, and microbial genomes.

Tools that investigate enrichment of biological functions or interactions often use the Gene Ontology (GO) categorizations, i.e. the GO terms to determine whether any have significantly modified representation in a given list of genes. Therefore, to best use and interpret the results from these functional analysis tools, it is helpful to have a good understanding of the GO terms themselves and their organization.

GO Ontologies

To describe the roles of genes and gene products, GO terms are organized into three independent controlled vocabularies (ontologies) in a species-independent manner:

  • Biological process: refers to the biological role involving the gene or gene product, and could include "transcription", "signal transduction", and "apoptosis". A biological process generally involves a chemical or physical change of the starting material or input.
  • Molecular function: represents the biochemical activity of the gene product, such activities could include "ligand", "GTPase", and "transporter".
  • Cellular component: refers to the location in the cell of the gene product. Cellular components could include "nucleus", "lysosome", and "plasma membrane".

Each GO term has a term name (e.g. DNA repair) and a unique term accession number (<0005125>), and a single gene product can be associated with many GO terms, since a single gene product "may function in several processes, contain domains that carry out diverse molecular functions, and participate in multiple alternative interactions with other proteins, organelles or locations in the cell". See more here.

GO term hierarchy

Some gene products are well-researched, with vast quantities of data available regarding their biological processes and functions. However, other gene products have very little data available about their roles in the cell.

For example, the protein, "p53", would contain a wealth of information on it's roles in the cell, whereas another protein might only be known as a "membrane-bound protein" with no other information available.

The GO ontologies were developed to describe and query biological knowledge with differing levels of information available. To do this, GO ontologies are loosely hierarchical, ranging from general, 'parent', terms to more specific, 'child' terms. The GO ontologies are "loosely" hierarchical since 'child' terms can have multiple 'parent' terms.

Some genes with less information may only be associated with general 'parent' terms or no terms at all, while other genes with a lot of information be associated with many terms.

From Nature Reviews Cancer 7, 23-34 (January 2007)

Tip

More tips for working with GO can be found here

clusterProfiler

We will be using clusterProfiler to perform over-representation analysis on GO terms associated with our list of significant genes. The tool takes as input a significant gene list and a background gene list and performs statistical enrichment analysis using hypergeometric testing. The basic arguments allow the user to select the appropriate organism and GO ontology (BP, CC, MF) to test.

Running clusterProfiler

To run clusterProfiler GO over-representation analysis, we will change our gene names into Ensembl IDs, since the tool works a bit easier with the Ensembl IDs. Then load the following libraries:

# Load libraries
library(DOSE)
library(pathview)
library(clusterProfiler)
library(org.Hs.eg.db)

To perform the over-representation analysis, we need a list of background genes and a list of significant genes. For our background dataset we will use all genes tested for differential expression (all genes in our results table). For our significant gene list we will use genes with p-adjusted values less than 0.05 (we could include a fold change threshold too if we have many DE genes).

## Create background dataset for hypergeometric testing using all genes tested for significance in the results
allCont_genes <- dplyr::filter(res_ids, !is.na(gene)) %>% 
  pull(gene) %>% 
  as.character()

## Extract significant results
sigCont <- dplyr::filter(res_ids, padj < 0.05 & !is.na(gene))

sigCont_genes <- sigCont %>% 
  pull(gene) %>% 
  as.character()

Now we can perform the GO enrichment analysis and save the results:

## Run GO enrichment analysis 
ego <- enrichGO(gene = sigCont_genes, 
                universe = allCont_genes,
                keyType = "ENSEMBL",
                OrgDb = org.Hs.eg.db, 
                ont = "BP", 
                pAdjustMethod = "BH", 
                qvalueCutoff = 0.05, 
                readable = TRUE)

Note

The different organisms with annotation databases available to use with for the OrgDb argument can be found here.

Also, the keyType argument may be coded as keytype in different versions of clusterProfiler.

Finally, the ont argument can accept either "BP" (Biological Process), "MF" (Molecular Function), and "CC" (Cellular Component) subontologies, or "ALL" for all three.

## Output results from GO analysis to a table
cluster_summary <- data.frame(ego)
cluster_summary

write.csv(cluster_summary, "../Results/clusterProfiler_Cont-Vamp.csv")
ID Description GeneRatio BgRatio pvalue p.adjust qvalue geneID Count
GO:0002449 lymphocyte mediated immunity 259/3662 436/15509 3.55473e-59 2.20322e-55 1.32498e-55 BTK/HFE/CD74/SLAMF7/TNFRSF1B/PARP3/FOXP3/FCGR2B/TBX21/MLH1/IL4R/PTPRC/P2RX7/ICAM1/MSH2/IL12RB1/GZMB/CD40/SMAD7/TLR8/CD40LG/IL21R/NBN/FCER2/LILRB1/IL27RA/CLC/TGFB1/AHR/EXOSC3/GATA3/PPP3CB/C1QBP/NSD2/CTSC/HPX/CD81/AICDA/IL12B/IL4/BCL6/CD160/PRDX1/ARG1/CLU/SHLD2/IL1B/CD70/C3/FOXJ1/NECTIN2/ULBP2/NDFIP1/ARL8B/IL6/IL10/IL21/SLC15A4/ARRB2/LYST/IL18/MR1/CD96/CD8A/CD1A/CD1C/CD1B/TNFSF13/PRKCD/MBL2/NOD2/KIR3DL1/FADD/INPP5D/LGALS9/SERPINB9/KIF5B/STAT5B/LIG4/LEP/CD19/CD28/HLA-DQB1/PRF1/MICA/BTN3A2/LILRB4/CARD9/ZP3/KIR2DL4/HMGB1/TUBB/CD55/HLA-DQA1/CR1/HLA-DOA/TAP2/TNF/HLA-E/HLA-G/TAP2/HLA-DQB1/TAP2/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/TAP2/HLA-B/HLA-DQA1/NCR3/HLA-DPB1/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-DQA1/HLA-E/NCR3/HLA-DQB1/HLA-DQA1/TAP2/LTA/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/TNF/HLA-E/LTA/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/MICA/HLA-DQB1/HLA-DPA1/LTA/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/HLA-B/TAP2/TNF/MICA/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-DQA1/HLA-E/HLA-DPB1/NCR3/NCR3/HLA-G/HLA-DQA1/TAP2/HLA-DPB1/NCR3/LTA/HLA-DQA1/PTPRC/KIR2DL4/B2M/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR3DL1/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/LILRB4/KIR2DL4/HLA-G/KIR3DL1/KIR3DL1/KIR3DL1/LILRB1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR3DL1/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/LILRB4/KIR3DL1/KIR2DL4/LILRB4/KIR2DL4/KIR3DL1/INPP5D/KIR3DL1/KIR3DL1/KIR3DL1/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR3DL1 259
GO:0001906 cell killing 180/3662 281/15509 6.369e-48 1.97375e-44 1.18698e-44 TYROBP/LTF/SLAMF7/SPI1/FCGR2B/STXBP2/PTPRC/CD59/P2RX7/ICAM1/LYZ/HSP90AB1/IL12RB1/CTSG/GZMB/FCER2/LILRB1/HAMP/MAPK8/PPP3CB/CTSC/IFNG/IL12B/IL4/GNLY/CD160/PRDX1/ARG1/SEMG1/H2BC11/C3/NECTIN2/ULBP2/ARL8B/IL21/ARRB2/LYST/IL18/MR1/CD1A/CD1C/CD1B/SYK/KIR3DL1/FADD/CX3CR1/LGALS9/ITGAM/SERPINB9/KIF5B/BCL2L1/STAT5B/LEP/F2/PRF1/MICA/KIR2DL4/TUBB/CD55/ELANE/HMGN2/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/TAP2/MICA/HLA-G/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/PTPRC/KIR2DL4/B2M/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR3DL1/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/HLA-G/KIR3DL1/KIR3DL1/KIR3DL1/LILRB1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR3DL1/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/ELANE/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR3DL1/KIR3DL1/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR3DL1 180
GO:1903039 positive regulation of leukocyte cell-cell adhesion 196/3662 320/15509 1.02609e-47 2.1199e-44 1.27487e-44 BAD/SELE/CD4/IGF1/CD74/RUNX3/CD44/ARID1B/FOXP3/AP3D1/RHOA/CBFB/GLI2/ACTB/IL4R/PTPRC/IL12RB1/ABL1/SMARCB1/XBP1/CD40LG/NFAT5/PYCARD/CSK/IL7/LILRB1/IL27RA/JAK3/GATA3/MAP3K8/ZMIZ1/SMARCD2/CCL2/EFNB3/ZBTB16/CD5/MDK/CD81/IFNG/IL12B/IL4/BCL6/CD86/HES1/IL1A/ZAP70/ITGA4/IGFBP2/CD160/ARID1A/MYB/FOXO3/NR4A3/GPAM/CD80/SOX4/IL1B/TNFSF9/CD70/CCR7/EPO/RARA/FLOT2/AP3B1/PTPN22/IL2RA/IL6/HLX/CCL21/IL21/SLC7A1/ABL2/DUSP10/IL2RG/IL18/RUNX1/TNFRSF13C/ICOSLG/ITGB2/VCAM1/TGFBR2/SPTA1/SHH/SYK/BRD7/RAG1/NOD2/FADD/RHOH/LGALS9/PTAFR/CCL19/KAT5/RELA/STAT5B/SELP/LEP/CD28/PTPN11/HLA-DQB1/KLHL25/IRAK1/SOCS1/LILRB4/ZP3/ARID2/HMGB1/CD55/FUT4/HLA-DQA1/CD47/SRC/ELANE/DPP4/PDCD1LG2/PNP/CR1/HLA-DOA/TNF/HLA-E/HLA-G/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/TNF/HLA-A/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/TNF/TNF/TNF/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/TNF/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/TNF/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/HLA-DQA1/PTPRC/CCL5/CD24/B2M/CCL5/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/ELANE/LILRB1/LILRB4/LILRB4 196
GO:0001909 leukocyte mediated cytotoxicity 163/3662 243/15509 1.80678e-47 2.79961e-44 1.68363e-44 TYROBP/SLAMF7/SPI1/FCGR2B/STXBP2/PTPRC/P2RX7/ICAM1/IL12RB1/CTSG/GZMB/LILRB1/PPP3CB/CTSC/IL12B/CD160/PRDX1/ARG1/NECTIN2/ULBP2/ARL8B/IL21/ARRB2/LYST/IL18/MR1/CD1A/CD1C/CD1B/KIR3DL1/FADD/CX3CR1/LGALS9/ITGAM/SERPINB9/KIF5B/STAT5B/LEP/F2/PRF1/MICA/KIR2DL4/TUBB/ELANE/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/TAP2/MICA/HLA-G/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/PTPRC/KIR2DL4/B2M/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR3DL1/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/HLA-G/KIR3DL1/KIR3DL1/KIR3DL1/LILRB1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR3DL1/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/ELANE/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR3DL1/KIR3DL1/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR3DL1 163
GO:0022409 positive regulation of cell-cell adhesion 214/3662 367/15509 4.54498e-47 5.63396e-44 3.38816e-44 BAD/SELE/CD4/IGF1/CD74/RUNX3/CD44/ARID1B/FOXP3/PTPRU/AP3D1/RHOA/CBFB/GLI2/ACTB/IL4R/PTPRC/CEACAM6/IL12RB1/ABL1/SMARCB1/XBP1/CTSG/BMP7/SMAD7/CD40LG/NFAT5/PIEZO1/PYCARD/CSK/TJP1/IL7/LILRB1/IL27RA/JAK3/GATA3/MAP3K8/ZMIZ1/SMARCD2/CCL2/EFNB3/ZBTB16/CD5/MDK/CD81/IFNG/IL12B/IL4/BCL6/CD86/WNT5A/HES1/IL1A/ZAP70/ITGA4/IGFBP2/CD160/ARID1A/MYB/FOXO3/NR4A3/GPAM/CD80/SOX4/IL1B/TNFSF9/CD70/CCR7/PODXL/EPO/RARA/FLOT2/AP3B1/PTPN22/IL2RA/ADAM19/IL6/HLX/IL10/CCL21/IL21/SLC7A1/ABL2/DUSP10/IL2RG/IL18/CXCL13/NODAL/DMTN/RUNX1/TNFRSF13C/ICOSLG/ITGB2/JAK1/VCAM1/TGFBR2/SPTA1/SHH/SYK/BRD7/RAG1/NOD2/FADD/RHOH/LGALS9/PTAFR/FGG/FGA/CCL19/KAT5/RELA/STAT5B/SELP/LEP/CD28/PTPN11/HLA-DQB1/KLHL25/IRAK1/SOCS1/LILRB4/ZP3/ARID2/HMGB1/CD55/FUT4/HLA-DQA1/CD47/SRC/ELANE/DPP4/PDCD1LG2/PNP/CR1/HLA-DOA/TNF/HLA-E/HLA-G/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/TNF/HLA-A/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/TNF/TNF/TNF/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/TNF/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/TNF/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/HLA-DQA1/PTPRC/CCL5/CD24/B2M/CCL5/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/TJP1/ELANE/LILRB1/LILRB4/LILRB4 214
GO:0002706 regulation of lymphocyte mediated immunity 172/3662 268/15509 5.39997e-46 5.57817e-43 3.35461e-43 BTK/HFE/TNFRSF1B/PARP3/FOXP3/FCGR2B/TBX21/MLH1/PTPRC/P2RX7/MSH2/IL12RB1/CD40/SMAD7/FCER2/LILRB1/IL27RA/CLC/TGFB1/AHR/EXOSC3/GATA3/PPP3CB/NSD2/HPX/CD81/IL12B/IL4/BCL6/CD160/ARG1/SHLD2/IL1B/C3/FOXJ1/NECTIN2/NDFIP1/IL6/IL10/IL21/SLC15A4/ARRB2/IL18/MR1/CD96/CD1A/CD1C/CD1B/TNFSF13/NOD2/FADD/LGALS9/SERPINB9/STAT5B/LEP/CD28/MICA/LILRB4/ZP3/KIR2DL4/HMGB1/CD55/CR1/TAP2/TNF/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/LTA/HLA-A/HLA-DRA/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-G/MICA/LTA/HLA-A/HLA-B/TAP2/TNF/MICA/HLA-G/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/LTA/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 172
GO:0002703 regulation of leukocyte mediated immunity 196/3662 327/15509 1.12955e-45 1.00014e-42 6.01465e-43 BTK/HFE/TYROBP/TNFRSF1B/GAB2/PARP3/C12orf4/FOXP3/SPI1/FCGR2B/TBX21/MLH1/STXBP2/IL4R/DDX1/PTPRC/MAVS/P2RX7/ICAM1/MSH2/IL12RB1/CD40/SMAD7/GATA1/FCER2/LILRB1/IL27RA/CLC/TGFB1/JAK3/AHR/EXOSC3/GATA3/PPP3CB/NSD2/HPX/CD81/IL12B/IL4/BCL6/SNX4/CD160/ARG1/VAMP8/SHLD2/IL1B/C3/RAC2/FOXJ1/NECTIN2/NDFIP1/IL6/IL10/STXBP1/TLR4/IL21/SLC15A4/ARRB2/IL18/MR1/CD96/KIT/CD1A/CD1C/CD1B/ITGB2/TNFSF13/TLR3/SYK/NOD2/FADD/CX3CR1/LGALS9/PTAFR/ITGAM/SERPINB9/STAT5B/LEP/CD28/MICA/LILRB4/ZP3/KIR2DL4/HMGB1/CD55/CR1/TAP2/TNF/HLA-E/HLA-G/CD177/TAP2/TAP2/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/LTA/HLA-A/HLA-DRA/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-G/MICA/LTA/HLA-A/HLA-B/TAP2/TNF/MICA/HLA-G/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/LTA/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 196
GO:0002440 production of molecular mediator of immune response 198/3662 336/15509 1.49188e-44 1.04211e-41 6.26706e-42 BTK/HFE/CD22/CD74/TNFRSF1B/PARP3/FOXP3/TCF3/FCGR2B/TBX21/MLH1/IL4R/DDX1/PTPRC/MAVS/P2RX7/MSH2/XBP1/CD40/SMAD7/CD40LG/ACP5/PYCARD/NBN/LILRB1/IL27RA/CLC/GPI/TGFB1/JAK3/NOD1/EXOSC3/GATA3/NSD2/HPX/CD81/AICDA/IL17A/IL4/IL5/BCL6/CD86/WNT5A/CD160/ARG1/NR4A3/CD244/SHLD2/PKN1/IL1B/NDFIP1/EPHB2/PTPN22/CD36/IL6/IL10/TLR4/IL21/SLC15A4/TMBIM6/IL18/CD96/KIT/NLRX1/TNFSF13/MAPKAPK2/TLR3/SYK/NOD2/LIG4/CD28/HLA-DQB1/LACC1/PRG2/LILRB4/CARD9/KIR2DL4/CD55/TLR7/HLA-DQA1/ELANE/UBE2J1/CR1/HLA-DOA/TNF/HLA-E/HLA-G/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/TNF/HLA-A/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/TNF/TNF/TNF/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/TNF/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/TNF/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/PRKDC/HLA-DQA1/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/ELANE/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/GPI/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 198
GO:0002697 regulation of immune effector process 240/3662 445/15509 1.51323e-44 1.04211e-41 6.26706e-42 BTK/HFE/TYROBP/CD22/CD74/TNFRSF1B/GRN/GAB2/PARP3/C12orf4/FOXP3/SPI1/FCGR2B/TBX21/MLH1/STXBP2/IL4R/DDX1/PTPRC/CD59/MAVS/P2RX7/ICAM1/MSH2/IL12RB1/XBP1/CD40/SMAD7/GATA1/CD40LG/ACP5/PYCARD/FCER2/LILRB1/IL27RA/CLC/GPI/TGFB1/JAK3/NOD1/AHR/EXOSC3/GATA3/PPP3CB/C1QBP/NSD2/HPX/CD81/IFNG/IL17A/IL12B/IL4/IL5/BCL6/CD86/WNT5A/SNX4/CD160/MYB/ARG1/VAMP8/NR4A3/CD80/CD244/SHLD2/PKN1/IL1B/C3/RAC2/FOXJ1/NECTIN2/NDFIP1/RARA/EPHB2/PTPN22/CD36/IL6/HLX/IL10/STXBP1/TLR4/IRF4/DDX60/IL21/SLC15A4/TMBIM6/ARRB2/DUSP10/IL18/MR1/CD96/KIT/APPL1/CD1A/CD1C/CD1B/ITGB2/NLRX1/TNFSF13/MAPKAPK2/TLR3/SYK/MBL2/NOD2/FADD/CX3CR1/LGALS9/PTAFR/ITGAM/SERPINB9/CCL19/STAT5B/LEP/A2M/CD28/LACC1/MICA/PRG2/LILRB4/CARD9/ZP3/KIR2DL4/HMGB1/CD55/TLR7/CD47/UBE2J1/CR1/TAP2/TNF/HLA-E/HLA-G/CD177/TAP2/TAP2/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/LTA/HLA-A/HLA-DRA/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-G/MICA/LTA/HLA-A/HLA-B/TAP2/TNF/MICA/HLA-G/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/LTA/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/GPI/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 240
GO:0002699 positive regulation of immune effector process 195/3662 332/15509 1.37064e-43 8.49521e-41 5.10887e-41 BTK/TYROBP/CD74/GAB2/C12orf4/FOXP3/SPI1/TBX21/MLH1/STXBP2/IL4R/DDX1/PTPRC/MAVS/P2RX7/MSH2/IL12RB1/XBP1/CD40/GATA1/PYCARD/FCER2/LILRB1/GPI/TGFB1/NOD1/EXOSC3/GATA3/NSD2/HPX/CD81/IFNG/IL17A/IL12B/IL4/IL5/CD86/WNT5A/SNX4/CD160/MYB/ARG1/VAMP8/NR4A3/CD80/CD244/SHLD2/IL1B/C3/RAC2/NECTIN2/RARA/EPHB2/PTPN22/CD36/IL6/HLX/IL10/STXBP1/TLR4/DDX60/IL21/IL18/MR1/KIT/CD1A/CD1C/CD1B/ITGB2/TNFSF13/MAPKAPK2/TLR3/SYK/MBL2/NOD2/FADD/LGALS9/PTAFR/ITGAM/CCL19/STAT5B/CD28/LACC1/CARD9/ZP3/KIR2DL4/CD55/TLR7/CR1/TAP2/TNF/HLA-E/HLA-G/CD177/TAP2/TAP2/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/LTA/HLA-A/HLA-DRA/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-G/LTA/HLA-A/HLA-B/TAP2/TNF/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/LTA/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/GPI/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 195
GO:0002696 positive regulation of leukocyte activation 228/3662 418/15509 2.03813e-43 1.14839e-40 6.90622e-41 BAD/CD38/CD4/BTK/TYROBP/IGF1/CD74/RUNX3/GAB2/ARID1B/FOXP3/AP3D1/KARS1/RHOA/CBFB/TBX21/GLI2/ACTB/MLH1/IL4R/PTPRC/MSH2/IL12RB1/ABL1/SMARCB1/XBP1/CD40/NFATC2/GATA1/CD40LG/PYCARD/CSK/IL7/LILRB1/IL27RA/TGFB1/JAK3/HAMP/EXOSC3/GATA3/MAP3K8/ZMIZ1/SMARCD2/CCL2/EFNB3/NSD2/CTSC/ZBTB16/CD5/MDK/CD81/IFNG/IL12B/IL4/IL5/BCL6/CD86/WNT5A/HES1/SNX4/IL1A/ZAP70/IGFBP2/CD160/MPL/ARID1A/MYB/VAMP8/FOXO3/NR4A3/GPAM/CD80/SHLD2/CDKN1A/SOX4/IL1B/TNFSF9/CD70/CCR7/NECTIN2/EPO/RARA/FLOT2/AP3B1/EPHB2/PTPN22/IL2RA/AKIRIN2/IL6/HLX/IL10/STXBP1/TLR4/CCL21/THBS1/IL21/SLC7A1/ABL2/DUSP10/IL2RG/IL18/MMP14/RUNX1/TNFRSF13C/ICOSLG/ITGB2/TNFSF13/VCAM1/TGFBR2/SPTA1/SHH/SYK/BRD7/RAG1/NOD2/FADD/RHOH/TNIP2/INPP5D/LGALS9/PTAFR/ITGAM/CCL19/KAT5/STAT5B/LEP/CD28/PTPN11/HLA-DQB1/KLHL25/SOCS1/LILRB4/ZP3/ARID2/BLOC1S3/HMGB1/CD55/HLA-DQA1/CD47/SRC/DPP4/PDCD1LG2/PNP/CR1/HLA-DOA/TNF/HLA-E/HLA-G/CD177/CRLF2/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/TNF/HLA-A/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/TNF/TNF/TNF/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/TNF/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/TNF/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/CEBPA/PRKDC/HLA-DQA1/PTPRC/CCL5/CD24/B2M/CCL5/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/MIF/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4/INPP5D 228
GO:0002228 natural killer cell mediated immunity 126/3662 173/15509 6.04231e-43 3.12085e-40 1.87683e-40 SLAMF7/GZMB/LILRB1/IL12B/CD160/PRDX1/NECTIN2/ULBP2/ARL8B/IL21/ARRB2/LYST/IL18/CD96/KIR3DL1/LGALS9/SERPINB9/KIF5B/STAT5B/LEP/MICA/KIR2DL4/TUBB/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/KIR2DL4/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR3DL1/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/HLA-G/KIR3DL1/KIR3DL1/KIR3DL1/LILRB1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR3DL1/KIR3DL1/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR3DL1 126
GO:0042267 natural killer cell mediated cytotoxicity 125/3662 171/15509 6.76603e-43 3.22584e-40 1.93996e-40 SLAMF7/GZMB/LILRB1/IL12B/CD160/PRDX1/NECTIN2/ULBP2/ARL8B/IL21/ARRB2/LYST/IL18/KIR3DL1/LGALS9/SERPINB9/KIF5B/STAT5B/LEP/MICA/KIR2DL4/TUBB/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/KIR2DL4/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR3DL1/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/HLA-G/KIR3DL1/KIR3DL1/KIR3DL1/LILRB1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR3DL1/KIR3DL1/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR3DL1/KIR3DL1/KIR2DL4/KIR2DL4/KIR3DL1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR3DL1 125
GO:1903037 regulation of leukocyte cell-cell adhesion 222/3662 405/15509 9.49056e-43 4.20161e-40 2.52677e-40 BAD/SELE/CD4/HFE/IGF1/CD74/RUNX3/CD44/ARID1B/FOXP3/AP3D1/RHOA/CBFB/FCGR2B/TBX21/GLI2/ACTB/IL4R/ARG2/PTPRC/IL12RB1/ABL1/SMARCB1/XBP1/CTSG/SMAD7/CD40LG/NFAT5/PYCARD/CSK/IL7/LILRB1/IL27RA/JAK3/GATA3/CXCL12/MAP3K8/ZMIZ1/SMARCD2/CCL2/EFNB3/ZBTB16/CD5/MDK/CD81/IFNG/IL12B/IL4/BCL6/CD86/HES1/IL1A/ZAP70/ITGA4/IGFBP2/CD160/ARID1A/MYB/ARG1/FOXO3/NR4A3/GPAM/CD80/SOX4/IL1B/TNFSF9/CD70/CCR7/TWSG1/FOXJ1/EPO/ASS1/NDFIP1/RARA/FLOT2/AP3B1/SFTPD/PTPN22/IL2RA/IL6/HLX/IL10/CCL21/IL21/SLC7A1/ABL2/DUSP10/TNFRSF21/IL2RG/IL18/RUNX1/TNFRSF13C/ICOSLG/ITGB2/VCAM1/TGFBR2/SPTA1/CTLA4/CASP3/SHH/SYK/BRD7/RAG1/NOD2/PRDX2/FADD/RHOH/LGALS9/PTAFR/CEBPB/CCL19/KAT5/RELA/STAT5B/SELP/LEP/GLMN/RAG2/PTPN2/ZDHHC21/CD28/PTPN11/HLA-DQB1/KLHL25/IRAK1/SOCS1/LILRB4/ZP3/ARID2/HMGB1/CD55/FUT4/HLA-DQA1/CD47/SRC/ELANE/DPP4/PDCD1LG2/NRARP/PNP/CR1/HLA-DOA/TNF/HLA-E/HLA-G/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/TNF/HLA-A/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/TNF/TNF/TNF/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/TNF/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/TNF/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/HLA-DQA1/PTPRC/CCL5/CD24/B2M/CCL5/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/ELANE/LILRB1/LILRB4/LILRB4/PTEN/ITCH 222
GO:0050867 positive regulation of cell activation 232/3662 433/15509 1.93124e-42 7.97987e-40 4.79896e-40 BAD/CD38/CD4/BTK/TYROBP/IGF1/CD74/RUNX3/GAB2/ARID1B/FOXP3/AP3D1/KARS1/RHOA/CBFB/TBX21/GLI2/ACTB/MLH1/IL4R/PTPRC/MSH2/IL12RB1/ABL1/SMARCB1/XBP1/CD40/NFATC2/GATA1/CD40LG/PYCARD/CSK/IL7/LILRB1/IL27RA/TGFB1/JAK3/HAMP/EXOSC3/GATA3/ACTA2/MAP3K8/ZMIZ1/SMARCD2/CCL2/EFNB3/NSD2/CTSC/ZBTB16/CD5/MDK/CD81/IFNG/IL12B/IL4/IL5/PDGFRB/BCL6/CD86/WNT5A/HES1/SNX4/IL1A/ZAP70/IGFBP2/CD160/MPL/ARID1A/MYB/VAMP8/FOXO3/NR4A3/GPAM/CD80/SHLD2/CDKN1A/SOX4/IL1B/TNFSF9/CD70/CCR7/SOX15/NECTIN2/EPO/RARA/FLOT2/AP3B1/EPHB2/PTPN22/IL2RA/AKIRIN2/IL6/HLX/IL10/STXBP1/TLR4/CCL21/THBS1/IL21/SLC7A1/ABL2/DUSP10/IL2RG/IL18/MMP14/RUNX1/TNFRSF13C/ICOSLG/ITGB2/TNFSF13/VCAM1/TGFBR2/SPTA1/SHH/SYK/BRD7/RAG1/NOD2/FADD/RHOH/TNIP2/INPP5D/LGALS9/PTAFR/ITGAM/CCL19/KAT5/STAT5B/SELP/LEP/CD28/PTPN11/HLA-DQB1/KLHL25/SOCS1/LILRB4/ZP3/ARID2/BLOC1S3/HMGB1/CD55/HLA-DQA1/CD47/SRC/DPP4/PDCD1LG2/PNP/CR1/HLA-DOA/TNF/HLA-E/HLA-G/CD177/CRLF2/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/TNF/HLA-A/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/TNF/TNF/TNF/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/TNF/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/TNF/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/CEBPA/PRKDC/HLA-DQA1/PTPRC/CCL5/CD24/B2M/CCL5/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/MIF/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4/INPP5D 232
GO:0007159 leukocyte cell-cell adhesion 234/3662 439/15509 2.64361e-42 1.02407e-39 6.15857e-40 BAD/ITGAL/SELE/CD4/HFE/IGF1/CD74/RUNX3/CD44/ARID1B/FOXP3/AP3D1/RHOA/ROCK1/CBFB/FCGR2B/TBX21/GLI2/ADD2/ACTB/IL4R/ARG2/PTPRC/ICAM1/IL12RB1/ABL1/SMARCB1/XBP1/CTSG/BMP7/SMAD7/CD40LG/NFAT5/PYCARD/CSK/IL7/LILRB1/IL27RA/JAK3/GATA3/CXCL12/MAP3K8/ZMIZ1/SMARCD2/CCL2/EFNB3/ZBTB16/CD5/MDK/CD81/IFNG/IL12B/IL4/BCL6/CD86/HES1/IL1A/ZAP70/ITGA4/IGFBP2/CD160/ARID1A/MYB/ARG1/FOXO3/NR4A3/GPAM/CD80/SOX4/IL1B/TNFSF9/CD70/CCR7/RAC2/TWSG1/FOXJ1/EPO/ASS1/NDFIP1/RARA/FLOT2/AP3B1/SFTPD/PTPN22/IL2RA/NT5E/IL6/HLX/IL10/CCL21/IL21/SLC7A1/ABL2/DUSP10/TNFRSF21/MSN/IL2RG/ITGB1/IL18/RUNX1/TNFRSF13C/ICOSLG/ITGB2/VCAM1/TGFBR2/SPTA1/CTLA4/CASP3/SHH/SYK/BRD7/RAG1/NOD2/PRDX2/FADD/CX3CR1/RHOH/LGALS9/PTAFR/CEBPB/CCL19/KAT5/RELA/STAT5B/SELP/LEP/GLMN/RAG2/PTPN2/ZDHHC21/CD28/PTPN11/HLA-DQB1/KLHL25/IRAK1/SOCS1/LILRB4/ZP3/ARID2/HMGB1/CD55/FUT4/HLA-DQA1/CD47/SRC/ELANE/DPP4/PDCD1LG2/NRARP/PNP/CR1/HLA-DOA/TNF/HLA-E/HLA-G/CD177/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/TNF/HLA-A/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/TNF/TNF/TNF/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/TNF/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/TNF/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/HLA-DQA1/PECAM1/PTPRC/CCL5/CD24/B2M/CCL5/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/ELANE/LILRB1/LILRB4/LILRB4/PTEN/ITCH 234
GO:0050870 positive regulation of T cell activation 175/3662 289/15509 1.04299e-41 3.80264e-39 2.28684e-39 BAD/CD4/IGF1/CD74/RUNX3/ARID1B/FOXP3/AP3D1/RHOA/CBFB/GLI2/ACTB/IL4R/PTPRC/IL12RB1/ABL1/SMARCB1/XBP1/CD40LG/PYCARD/CSK/IL7/LILRB1/IL27RA/JAK3/GATA3/MAP3K8/ZMIZ1/SMARCD2/CCL2/EFNB3/ZBTB16/CD5/MDK/CD81/IFNG/IL12B/IL4/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/CD160/ARID1A/MYB/FOXO3/GPAM/CD80/SOX4/IL1B/TNFSF9/CD70/CCR7/EPO/RARA/FLOT2/AP3B1/PTPN22/IL2RA/IL6/HLX/CCL21/IL21/SLC7A1/ABL2/DUSP10/IL2RG/IL18/RUNX1/TNFRSF13C/ICOSLG/VCAM1/TGFBR2/SPTA1/SHH/SYK/BRD7/RAG1/NOD2/FADD/RHOH/LGALS9/CCL19/KAT5/STAT5B/LEP/CD28/PTPN11/HLA-DQB1/KLHL25/SOCS1/LILRB4/ZP3/ARID2/HMGB1/CD55/HLA-DQA1/CD47/SRC/DPP4/PDCD1LG2/PNP/CR1/HLA-DOA/HLA-E/HLA-G/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/HLA-DQA1/PTPRC/CCL5/CD24/B2M/CCL5/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4 175
GO:0002705 positive regulation of leukocyte mediated immunity 147/3662 223/15509 1.65737e-41 5.70688e-39 3.43202e-39 BTK/TYROBP/FOXP3/SPI1/TBX21/MLH1/DDX1/PTPRC/MAVS/P2RX7/MSH2/IL12RB1/CD40/FCER2/TGFB1/EXOSC3/GATA3/NSD2/HPX/CD81/IL12B/IL4/CD160/ARG1/SHLD2/IL1B/C3/NECTIN2/IL6/IL21/IL18/MR1/KIT/CD1A/CD1C/CD1B/ITGB2/TNFSF13/NOD2/FADD/PTAFR/ITGAM/STAT5B/CD28/ZP3/KIR2DL4/CD55/TAP2/TNF/HLA-E/HLA-G/CD177/TAP2/TAP2/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/LTA/HLA-A/HLA-DRA/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-G/LTA/HLA-A/HLA-B/TAP2/TNF/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/LTA/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 147
GO:0031341 regulation of cell killing 131/3662 188/15509 3.81479e-41 1.24442e-38 7.48375e-39 TYROBP/SPI1/FCGR2B/PTPRC/CD59/P2RX7/ICAM1/HSP90AB1/IL12RB1/FCER2/LILRB1/MAPK8/PPP3CB/IFNG/IL12B/IL4/CD160/ARG1/NECTIN2/IL21/ARRB2/MR1/CD1A/CD1C/CD1B/SYK/FADD/CX3CR1/LGALS9/ITGAM/SERPINB9/BCL2L1/STAT5B/LEP/PRF1/MICA/KIR2DL4/CD55/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/TAP2/MICA/HLA-G/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 131
GO:0002700 regulation of production of molecular mediator of immune response 155/3662 244/15509 1.02526e-40 3.17728e-38 1.91076e-38 BTK/HFE/CD22/CD74/TNFRSF1B/PARP3/FOXP3/FCGR2B/TBX21/MLH1/IL4R/DDX1/PTPRC/MAVS/P2RX7/MSH2/XBP1/CD40/SMAD7/CD40LG/ACP5/PYCARD/LILRB1/IL27RA/CLC/GPI/TGFB1/JAK3/NOD1/EXOSC3/GATA3/NSD2/HPX/CD81/IL17A/IL4/IL5/BCL6/CD86/WNT5A/CD160/ARG1/NR4A3/CD244/SHLD2/PKN1/IL1B/NDFIP1/EPHB2/PTPN22/CD36/IL6/IL10/TLR4/IL21/SLC15A4/TMBIM6/IL18/CD96/KIT/NLRX1/TNFSF13/MAPKAPK2/TLR3/SYK/NOD2/CD28/LACC1/PRG2/LILRB4/CARD9/KIR2DL4/CD55/TLR7/UBE2J1/CR1/TNF/HLA-E/HLA-G/TNF/HLA-E/HLA-A/HLA-A/HLA-G/TNF/HLA-A/HLA-A/HLA-E/HLA-A/TNF/TNF/TNF/HLA-A/HLA-E/TNF/HLA-E/HLA-G/HLA-A/TNF/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/GPI/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 155
GO:0002708 positive regulation of lymphocyte mediated immunity 137/3662 203/15509 1.66678e-40 4.91937e-38 2.95842e-38 BTK/FOXP3/TBX21/MLH1/PTPRC/P2RX7/MSH2/IL12RB1/CD40/FCER2/TGFB1/EXOSC3/GATA3/NSD2/HPX/CD81/IL12B/IL4/CD160/SHLD2/IL1B/C3/NECTIN2/IL6/IL21/IL18/MR1/CD1A/CD1C/CD1B/TNFSF13/NOD2/FADD/STAT5B/CD28/ZP3/KIR2DL4/CD55/TAP2/TNF/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/LTA/HLA-A/HLA-DRA/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-G/LTA/HLA-A/HLA-B/TAP2/TNF/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/LTA/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 137
GO:0031342 negative regulation of cell killing 85/3662 98/15509 4.46788e-40 1.25872e-37 7.56975e-38 FCGR2B/PTPRC/HSP90AB1/LILRB1/PPP3CB/IL4/ARRB2/CX3CR1/LGALS9/SERPINB9/MICA/KIR2DL4/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/PTPRC/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 85
GO:0002707 negative regulation of lymphocyte mediated immunity 100/3662 126/15509 5.28805e-40 1.42501e-37 8.56979e-38 HFE/PARP3/FOXP3/FCGR2B/TBX21/PTPRC/SMAD7/LILRB1/AHR/PPP3CB/BCL6/ARG1/FOXJ1/NDFIP1/ARRB2/CD96/NOD2/LGALS9/SERPINB9/MICA/LILRB4/KIR2DL4/CD55/CR1/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/PTPRC/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 100
GO:0001911 negative regulation of leukocyte mediated cytotoxicity 83/3662 95/15509 1.09506e-39 2.82799e-37 1.70071e-37 FCGR2B/PTPRC/LILRB1/PPP3CB/ARRB2/CX3CR1/LGALS9/SERPINB9/MICA/KIR2DL4/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/PTPRC/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 83
GO:0051251 positive regulation of lymphocyte activation 202/3662 368/15509 4.54752e-39 1.12742e-36 6.78012e-37 BAD/CD38/CD4/BTK/TYROBP/IGF1/CD74/RUNX3/ARID1B/FOXP3/AP3D1/RHOA/CBFB/TBX21/GLI2/ACTB/MLH1/IL4R/PTPRC/MSH2/IL12RB1/ABL1/SMARCB1/XBP1/CD40/NFATC2/CD40LG/PYCARD/CSK/IL7/LILRB1/IL27RA/TGFB1/JAK3/EXOSC3/GATA3/MAP3K8/ZMIZ1/SMARCD2/CCL2/EFNB3/NSD2/ZBTB16/CD5/MDK/CD81/IFNG/IL12B/IL4/IL5/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/CD160/MPL/ARID1A/MYB/FOXO3/GPAM/CD80/SHLD2/CDKN1A/SOX4/IL1B/TNFSF9/CD70/CCR7/EPO/RARA/FLOT2/AP3B1/EPHB2/PTPN22/IL2RA/AKIRIN2/IL6/HLX/IL10/TLR4/CCL21/IL21/SLC7A1/ABL2/DUSP10/IL2RG/IL18/MMP14/RUNX1/TNFRSF13C/ICOSLG/TNFSF13/VCAM1/TGFBR2/SPTA1/SHH/SYK/BRD7/RAG1/NOD2/FADD/RHOH/TNIP2/INPP5D/LGALS9/CCL19/KAT5/STAT5B/LEP/CD28/PTPN11/HLA-DQB1/KLHL25/SOCS1/LILRB4/ZP3/ARID2/BLOC1S3/HMGB1/CD55/HLA-DQA1/CD47/SRC/DPP4/PDCD1LG2/PNP/CR1/HLA-DOA/HLA-E/HLA-G/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/PRKDC/HLA-DQA1/PTPRC/CCL5/CD24/B2M/CCL5/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/MIF/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4/INPP5D 202
GO:0002716 negative regulation of natural killer cell mediated immunity 79/3662 89/15509 5.90243e-39 1.40705e-36 8.46174e-37 LILRB1/ARRB2/CD96/LGALS9/SERPINB9/MICA/KIR2DL4/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 79
GO:0001910 regulation of leukocyte mediated cytotoxicity 121/3662 172/15509 9.28807e-39 2.13213e-36 1.28222e-36 TYROBP/SPI1/FCGR2B/PTPRC/P2RX7/ICAM1/IL12RB1/LILRB1/PPP3CB/IL12B/CD160/ARG1/NECTIN2/IL21/ARRB2/MR1/CD1A/CD1C/CD1B/FADD/CX3CR1/LGALS9/ITGAM/SERPINB9/STAT5B/LEP/MICA/KIR2DL4/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/TAP2/MICA/HLA-G/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/HLA-DRA/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 121
GO:0045953 negative regulation of natural killer cell mediated cytotoxicity 78/3662 88/15509 2.25544e-38 4.99258e-36 3.00245e-36 LILRB1/ARRB2/LGALS9/SERPINB9/MICA/KIR2DL4/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 78
GO:0002704 negative regulation of leukocyte mediated immunity 103/3662 137/15509 2.22263e-37 4.75029e-35 2.85674e-35 HFE/PARP3/FOXP3/SPI1/FCGR2B/TBX21/PTPRC/SMAD7/LILRB1/JAK3/AHR/PPP3CB/BCL6/ARG1/FOXJ1/NDFIP1/ARRB2/CD96/NOD2/CX3CR1/LGALS9/SERPINB9/MICA/LILRB4/KIR2DL4/CD55/CR1/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/PTPRC/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 103
GO:0002718 regulation of cytokine production involved in immune response 123/3662 181/15509 6.00847e-37 1.24135e-34 7.46526e-35 BTK/HFE/CD74/TNFRSF1B/FOXP3/TBX21/DDX1/MAVS/P2RX7/SMAD7/ACP5/PYCARD/LILRB1/CLC/TGFB1/JAK3/NOD1/GATA3/CD81/IL4/BCL6/WNT5A/CD160/ARG1/NR4A3/IL1B/CD36/IL6/IL10/TLR4/IL18/CD96/KIT/NLRX1/MAPKAPK2/TLR3/SYK/NOD2/LACC1/PRG2/LILRB4/CARD9/KIR2DL4/CD55/TLR7/UBE2J1/TNF/HLA-E/HLA-G/TNF/HLA-E/HLA-A/HLA-A/HLA-G/TNF/HLA-A/HLA-A/HLA-E/HLA-A/TNF/TNF/TNF/HLA-A/HLA-E/TNF/HLA-E/HLA-G/HLA-A/TNF/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 123
GO:0002698 negative regulation of immune effector process 127/3662 192/15509 3.09235e-36 6.1827e-34 3.71816e-34 HFE/CD22/GRN/PARP3/FOXP3/SPI1/FCGR2B/TBX21/IL4R/PTPRC/CD59/SMAD7/ACP5/LILRB1/TGFB1/JAK3/AHR/PPP3CB/IL4/BCL6/ARG1/FOXJ1/NDFIP1/HLX/IL10/TMBIM6/ARRB2/DUSP10/CD96/APPL1/NLRX1/NOD2/CX3CR1/LGALS9/SERPINB9/A2M/MICA/PRG2/LILRB4/KIR2DL4/CD55/CD47/CR1/TNF/HLA-E/HLA-G/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/TNF/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/TNF/TNF/HLA-B/TNF/HLA-A/HLA-E/TNF/HLA-E/HLA-G/MICA/HLA-A/HLA-B/TNF/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/PTPRC/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 127
GO:0002367 cytokine production involved in immune response 123/3662 183/15509 3.36284e-36 6.5134e-34 3.91704e-34 BTK/HFE/CD74/TNFRSF1B/FOXP3/TBX21/DDX1/MAVS/P2RX7/SMAD7/ACP5/PYCARD/LILRB1/CLC/TGFB1/JAK3/NOD1/GATA3/CD81/IL4/BCL6/WNT5A/CD160/ARG1/NR4A3/IL1B/CD36/IL6/IL10/TLR4/IL18/CD96/KIT/NLRX1/MAPKAPK2/TLR3/SYK/NOD2/LACC1/PRG2/LILRB4/CARD9/KIR2DL4/CD55/TLR7/UBE2J1/TNF/HLA-E/HLA-G/TNF/HLA-E/HLA-A/HLA-A/HLA-G/TNF/HLA-A/HLA-A/HLA-E/HLA-A/TNF/TNF/TNF/HLA-A/HLA-E/TNF/HLA-E/HLA-G/HLA-A/TNF/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 123
GO:0050863 regulation of T cell activation 208/3662 399/15509 8.56357e-36 1.60839e-33 9.6726e-34 BAD/CD4/HFE/IGF1/CD74/RUNX3/TNFRSF1B/ARID1B/FOXP3/PRDM1/AP3D1/RHOA/CBFB/FCGR2B/TBX21/GLI2/ACTB/IL4R/ARG2/PTPRC/IL12RB1/ABL1/SMARCB1/XBP1/CTSG/SMAD7/CD40LG/PYCARD/CSK/IL7/LILRB1/IL27RA/CLC/JAK3/TNFSF8/GATA3/MAP3K8/ZMIZ1/SMARCD2/CCL2/EFNB3/ZBTB16/CD5/MDK/CD81/IFNG/IL12B/IL4/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/CD160/ARID1A/MYB/ARG1/FOXO3/GPAM/CD80/SOX4/IL1B/TNFSF9/CD70/CCR7/RAC2/TWSG1/FOXJ1/EPO/NDFIP1/RARA/FLOT2/AP3B1/SFTPD/PTPN22/IL2RA/IL6/HLX/IL10/CCL21/IRF4/IL21/SLC7A1/SOD1/ABL2/DUSP10/TNFRSF21/IL2RG/ZEB1/IL18/RUNX1/TNFRSF13C/ICOSLG/VCAM1/TGFBR2/SPTA1/CTLA4/CASP3/SHH/SYK/BRD7/RAG1/LMO1/NOD2/PRDX2/FADD/RHOH/LGALS9/PRELID1/CEBPB/CCL19/KAT5/STAT5B/LEP/GLMN/RAG2/PTPN2/CD28/PTPN11/HLA-DQB1/KLHL25/SOCS1/LILRB4/ZP3/ARID2/HMGB1/CD55/HLA-DQA1/CD47/SRC/DPP4/PDCD1LG2/NRARP/PNP/CR1/HLA-DOA/HLA-E/HLA-G/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/HLA-DQA1/PTPRC/CCL5/CD24/B2M/CCL5/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4/PTEN/ITCH 208
GO:1903706 regulation of hemopoiesis 202/3662 389/15509 1.80325e-34 3.28723e-32 1.97688e-32 BAD/PAF1/SCIN/CD4/BTK/TYROBP/LTF/SNAI2/CD74/RUNX3/HMGB3/ARID1B/FOXP3/PRDM1/AP3D1/SPI1/RHOA/CBFB/TFE3/FCGR2B/TBX21/GLI2/ACTB/IL4R/HOXA9/PTPRC/BRPF3/IL12RB1/ABL1/SMARCB1/XBP1/ACIN1/NFKBIA/RASSF2/SMAD7/GATA1/SFRP1/IL7/LILRB1/TGFB1/JAK3/PTN/HOXA5/GATA3/ZMIZ1/CSF3/SMARCD2/ZBTB16/MDK/IFNG/NEDD9/MAPK14/IL17A/HSPA9/IL12B/IL4/IL5/BCL6/CD86/ZAP70/STAT1/ID2/MPL/ARID1A/MYB/FOXO3/CSF3R/PTK2B/IAPP/CD80/INHBA/SOX4/TNFSF9/PRMT1/ZFP36/LIF/LRRC17/FOXJ1/NDFIP1/RARA/PIAS3/AP3B1/NOTCH2/IL2RA/ABCB10/HLX/IL10/TLR4/IRF4/RB1/CUL4A/SKIC8/SOD1/ARNT/DUSP10/MEIS1/TCTA/PIK3R1/PURB/IL2RG/ZEB1/IL18/POU4F2/POU4F1/ZFP36L2/PRKCA/GABPA/KLF10/BRPF1/MMP14/RUNX1/TAL1/MYSM1/RBM15/TGFBR2/CTLA4/PF4/SLC9B2/TLR3/SHH/TNFRSF11B/SYK/BRD7/RAG1/PRDX2/FADD/RHOH/INPP5D/LGALS9/PRELID1/FOS/CEBPB/CCL19/RARG/KAT5/ESRRA/GPR137/STAT5B/RAG2/PTPN2/CD28/CTNNBIP1/ADIPOQ/KLHL25/CSF1/CIB1/SOCS1/ZFP36L1/LILRB4/ARID2/HMGB1/NRARP/MTOR/PNP/CR1/MAFB/HLA-DOA/TNF/HLA-G/HLA-DRA/TNF/HLA-B/HLA-G/HLA-B/TNF/HLA-B/HLA-DRA/TNF/TNF/HLA-B/TNF/HLA-DRA/TNF/HLA-G/HLA-B/TNF/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/EIF6/CEBPA/PRKDC/PTPRC/H4C15/H4C14/H4C12/B2M/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/H4C5/LILRB1/H4C4/HLA-DRA/LILRB1/LILRB4/LILRB4/INPP5D 202
GO:0002702 positive regulation of production of molecular mediator of immune response 120/3662 184/15509 2.12267e-33 3.75895e-31 2.26057e-31 BTK/CD74/TBX21/MLH1/IL4R/DDX1/PTPRC/MAVS/P2RX7/MSH2/XBP1/CD40/PYCARD/LILRB1/GPI/TGFB1/NOD1/EXOSC3/GATA3/NSD2/HPX/CD81/IL17A/IL4/IL5/CD86/WNT5A/CD160/NR4A3/CD244/SHLD2/IL1B/EPHB2/PTPN22/CD36/IL6/IL10/TLR4/IL21/IL18/KIT/TNFSF13/MAPKAPK2/TLR3/SYK/NOD2/CD28/LACC1/CARD9/KIR2DL4/CD55/TLR7/HLA-E/HLA-G/HLA-E/HLA-A/HLA-A/HLA-G/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/PTPRC/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/GPI/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 120
GO:0042269 regulation of natural killer cell mediated cytotoxicity 90/3662 119/15509 3.66983e-33 6.31823e-31 3.79967e-31 LILRB1/IL12B/CD160/NECTIN2/IL21/ARRB2/LGALS9/SERPINB9/STAT5B/LEP/MICA/KIR2DL4/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 90
GO:0002715 regulation of natural killer cell mediated immunity 91/3662 122/15509 1.05784e-32 1.77203e-30 1.06567e-30 LILRB1/IL12B/CD160/NECTIN2/IL21/ARRB2/CD96/LGALS9/SERPINB9/STAT5B/LEP/MICA/KIR2DL4/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 91
GO:0002460 adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 192/3662 371/15509 1.51397e-32 2.46936e-30 1.48503e-30 TMEM98/CD4/BTK/HFE/SLC11A1/CD74/TNFRSF1B/PARP3/FOXP3/FCGR2B/TBX21/MLH1/IL4R/PTPRC/P2RX7/ICAM1/MSH2/IL12RB1/CD40/SMAD7/TLR8/CD40LG/IL21R/NBN/FCER2/LILRB1/IL27RA/CLC/TGFB1/JAK3/AHR/EXOSC3/GATA3/PPP3CB/C1QBP/NSD2/CTSC/HPX/CD81/AICDA/IL12B/IL4/BCL6/TNFAIP3/ARG1/CLU/CD80/SHLD2/PKN1/IL1B/CD70/C3/FOXJ1/NECTIN2/NDFIP1/EPHB2/IL6/HLX/IL10/TLR4/IRF4/IL18BP/SLC15A4/NOTCH1/IL18/MR1/CD8A/CXCL13/CD1A/CD1C/CD1B/IL6R/TNFSF13/PRKCD/MBL2/NOD2/FADD/INPP5D/CCL19/LIG4/HRAS/CD19/CD28/HLA-DQB1/PRF1/MICA/BTN3A2/LILRB4/CARD9/ZP3/HMGB1/CD55/HLA-DQA1/ENTPD7/MTOR/CR1/HLA-DOA/TAP2/TNF/HLA-E/HLA-G/TAP2/HLA-DQB1/TAP2/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/TAP2/HLA-B/HLA-DQA1/HLA-DPB1/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/TAP2/LTA/HLA-DPB1/HLA-A/HLA-DRA/HLA-DQA1/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/TNF/HLA-E/LTA/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/MICA/HLA-DQB1/HLA-DPA1/LTA/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/HLA-B/TAP2/TNF/MICA/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/TAP2/HLA-DPB1/LTA/HLA-DQA1/PTPRC/B2M/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4/INPP5D 192
GO:0002683 negative regulation of immune system process 224/3662 469/15509 4.11086e-31 6.5331e-29 3.92889e-29 BTK/HFE/TYROBP/CD22/LTF/SNAI2/CD74/RUNX3/HMGB3/GRN/PARP3/FOXP3/SPI1/CBFB/FCGR2B/TBX21/MKRN2/IL4R/ARG2/PTPRC/PIBF1/CD59/CTSG/HCK/SMAD7/ACP5/SFRP1/LILRB1/IL27RA/TGFB1/JAK3/AHR/AMBP/CXCL12/PPP3CB/CCL2/LPXN/MDK/MAPK14/HSPA9/IL12B/IL4/BCL6/CD86/ID2/PADI2/CD160/TNFAIP3/ARG1/GPAM/IAPP/CD80/INHBA/PKN1/NR1D1/LRRC17/TWSG1/CD68/FOXJ1/NDFIP1/RARA/PIAS3/SYT11/SFTPD/PTPN22/IL2RA/HLX/IL10/TLR4/CCN3/CCL21/THBS1/CYP19A1/TMBIM6/CUL4A/FURIN/ARRB2/DUSP10/PARP1/TCTA/SLIT2/PLK2/PIK3R1/TNFRSF21/MERTK/CD96/APPL1/TSC22D3/RUNX1/PSMB4/NLRX1/ALOX15/FCRLB/CTLA4/CASP3/TLR3/SHH/TNFRSF11B/GPER1/SYK/NOD2/PRDX2/FADD/CX3CR1/INPP5D/LGALS9/SERPINB9/CEBPB/GPR137/GLMN/RAG2/BANF1/PTPN2/A2M/ADIPOQ/PLCB1/MICA/SOCS1/YTHDF3/PRG2/LILRB4/CNR2/KIR2DL4/HMGB1/CD55/CD47/SRC/DPP4/PDCD1LG2/NRARP/CR1/MAFB/ZDHHC18/HLA-DOA/TNF/HLA-E/HLA-G/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/TNF/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/TNF/TNF/HLA-B/TNF/HLA-A/HLA-E/TNF/HLA-E/HLA-G/MICA/HLA-A/HLA-B/TNF/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TNFRSF13B/CEBPA/PTPRC/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/INPP5D/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/PTEN/ITCH 224
GO:0002720 positive regulation of cytokine production involved in immune response 95/3662 135/15509 1.05248e-30 1.63081e-28 9.80741e-29 CD74/TBX21/DDX1/MAVS/P2RX7/PYCARD/LILRB1/NOD1/GATA3/CD81/IL4/WNT5A/CD160/NR4A3/IL1B/CD36/IL6/TLR4/IL18/KIT/MAPKAPK2/TLR3/SYK/NOD2/LACC1/CARD9/KIR2DL4/CD55/TLR7/HLA-E/HLA-G/HLA-E/HLA-A/HLA-A/HLA-G/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 95
GO:0002370 natural killer cell cytokine production 55/3662 59/15509 3.91638e-30 5.77946e-28 3.47567e-28 CD160/CD96/KIR2DL4/HLA-E/HLA-G/HLA-E/HLA-G/HLA-E/HLA-E/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 55
GO:0002727 regulation of natural killer cell cytokine production 55/3662 59/15509 3.91638e-30 5.77946e-28 3.47567e-28 CD160/CD96/KIR2DL4/HLA-E/HLA-G/HLA-E/HLA-G/HLA-E/HLA-E/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 55
GO:1902105 regulation of leukocyte differentiation 163/3662 304/15509 4.26102e-30 6.14181e-28 3.69358e-28 BAD/CD4/BTK/TYROBP/LTF/CD74/RUNX3/HMGB3/ARID1B/FOXP3/PRDM1/AP3D1/RHOA/CBFB/TFE3/FCGR2B/TBX21/GLI2/ACTB/IL4R/PTPRC/IL12RB1/ABL1/SMARCB1/XBP1/ACIN1/RASSF2/SMAD7/SFRP1/IL7/LILRB1/TGFB1/JAK3/GATA3/ZMIZ1/SMARCD2/ZBTB16/MDK/IFNG/NEDD9/IL17A/IL12B/IL4/IL5/BCL6/CD86/ZAP70/ID2/ARID1A/MYB/FOXO3/IAPP/CD80/INHBA/SOX4/TNFSF9/LIF/LRRC17/FOXJ1/NDFIP1/RARA/PIAS3/AP3B1/NOTCH2/IL2RA/HLX/IL10/TLR4/IRF4/RB1/CUL4A/SOD1/DUSP10/TCTA/PIK3R1/IL2RG/ZEB1/IL18/POU4F2/POU4F1/ZFP36L2/PRKCA/KLF10/MMP14/RUNX1/TGFBR2/CTLA4/PF4/SLC9B2/TLR3/SHH/TNFRSF11B/SYK/BRD7/RAG1/PRDX2/FADD/RHOH/INPP5D/LGALS9/PRELID1/FOS/CEBPB/CCL19/KAT5/ESRRA/GPR137/STAT5B/RAG2/PTPN2/CD28/CTNNBIP1/ADIPOQ/KLHL25/CSF1/SOCS1/ZFP36L1/LILRB4/ARID2/HMGB1/NRARP/MTOR/PNP/CR1/MAFB/HLA-DOA/TNF/HLA-G/HLA-DRA/TNF/HLA-B/HLA-G/HLA-B/TNF/HLA-B/HLA-DRA/TNF/TNF/HLA-B/TNF/HLA-DRA/TNF/HLA-G/HLA-B/TNF/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/PRKDC/PTPRC/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4/INPP5D 163
GO:0002729 positive regulation of natural killer cell cytokine production 54/3662 58/15509 1.56409e-29 2.20323e-27 1.32499e-27 CD160/KIR2DL4/HLA-E/HLA-G/HLA-E/HLA-G/HLA-E/HLA-E/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 54
GO:0002832 negative regulation of response to biotic stimulus 111/3662 176/15509 4.53432e-29 6.24527e-27 3.75579e-27 LTF/GRN/FOXP3/SIRT2/ARG2/RIOK3/LILRB1/AHR/C1QBP/TNFAIP3/ARG1/PPM1B/TARBP2/ARRB2/DUSP10/PARP1/CD96/NLRX1/HTRA1/PRDX2/LGALS9/SERPINB9/BANF1/PTPN2/A2M/MICA/SIGIRR/YTHDF3/KIR2DL4/PCBP2/CR1/ZDHHC18/HLA-E/HLA-G/MICB/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/MICB/HLA-B/HLA-E/HLA-A/MICB/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICB/MICA/MICB/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/MICB/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/ITCH 111
GO:0019882 antigen processing and presentation 106/3662 165/15509 8.18936e-29 1.10343e-26 6.63582e-27 HFE/SLC11A1/CD74/AP3D1/FCGR2B/RAB10/ICAM1/PSME1/PYCARD/NOD1/RAB32/CCR7/CD68/AP3B1/ARL8B/CCL21/THBS1/MR1/CD8A/CD1A/CD1C/CD1B/ERAP2/NOD2/TAP1/CCL19/CALR/HLA-DQB1/HLA-DQA1/HLA-DOA/TAP2/HLA-E/HLA-G/TAP2/HLA-DQB1/TAP1/TAP2/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/TAP2/HLA-B/HLA-DQA1/HLA-DPB1/HLA-A/TAP1/HLA-A/HLA-B/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/TAP2/TAP1/HLA-DPB1/HLA-A/TAP1/HLA-DRA/HLA-DQA1/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/TAP1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/TAPBP/HLA-DQB1/HLA-DQA1/HLA-B/TAP2/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/TAP2/HLA-DPB1/HLA-DQA1/B2M/HLA-G/HLA-DRA 106
GO:0050777 negative regulation of immune response 135/3662 240/15509 7.42469e-28 9.79111e-26 5.8882e-26 HFE/GRN/PARP3/FOXP3/SPI1/FCGR2B/TBX21/MKRN2/IL4R/ARG2/PTPRC/CD59/HCK/SMAD7/LILRB1/IL27RA/JAK3/AHR/AMBP/PPP3CB/MAPK14/IL12B/IL4/BCL6/CD160/TNFAIP3/ARG1/FOXJ1/NDFIP1/HLX/IL10/FURIN/ARRB2/DUSP10/PARP1/PLK2/CD96/PSMB4/NLRX1/ALOX15/FCRLB/CTLA4/SYK/NOD2/INPP5D/LGALS9/SERPINB9/BANF1/PTPN2/A2M/MICA/YTHDF3/LILRB4/KIR2DL4/CD55/SRC/CR1/ZDHHC18/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/PTPRC/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB4/KIR2DL4/LILRB4/KIR2DL4/INPP5D/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 135
GO:0002822 regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 127/3662 220/15509 9.83664e-28 1.27016e-25 7.6385e-26 CD4/BTK/HFE/SLC11A1/TNFRSF1B/PARP3/FOXP3/FCGR2B/TBX21/MLH1/IL4R/PTPRC/P2RX7/MSH2/IL12RB1/CD40/SMAD7/FCER2/LILRB1/IL27RA/CLC/TGFB1/JAK3/AHR/EXOSC3/GATA3/PPP3CB/NSD2/HPX/CD81/IL12B/IL4/BCL6/TNFAIP3/ARG1/CD80/SHLD2/PKN1/IL1B/C3/FOXJ1/NECTIN2/NDFIP1/EPHB2/IL6/HLX/IL10/SLC15A4/IL18/MR1/CD1A/CD1C/CD1B/TNFSF13/NOD2/FADD/CCL19/CD28/LILRB4/CARD9/ZP3/HMGB1/CD55/CR1/TAP2/TNF/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/LTA/HLA-A/HLA-DRA/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-G/LTA/HLA-A/HLA-B/TAP2/TNF/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/LTA/PTPRC/B2M/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4 127
GO:0002819 regulation of adaptive immune response 132/3662 234/15509 1.99237e-27 2.52015e-25 1.51557e-25 CD4/BTK/HFE/SLC11A1/TNFRSF1B/PARP3/FOXP3/FCGR2B/TBX21/MLH1/IL4R/PTPRC/P2RX7/MSH2/IL12RB1/CD40/SMAD7/PYCARD/FCER2/LILRB1/IL27RA/CLC/TGFB1/JAK3/AHR/EXOSC3/GATA3/PPP3CB/NSD2/HPX/CD81/IL12B/IL4/BCL6/CD160/TNFAIP3/ARG1/CD80/SHLD2/PKN1/IL1B/C3/FOXJ1/NECTIN2/NDFIP1/EPHB2/AKIRIN2/IL6/HLX/IL10/SLC15A4/DUSP10/IL18/MR1/CD1A/CD1C/CD1B/ALOX15/TNFSF13/NOD2/FADD/CCL19/CD28/LILRB4/CARD9/ZP3/HMGB1/CD55/CR1/TAP2/TNF/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/LTA/HLA-A/HLA-DRA/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-G/LTA/HLA-A/HLA-B/TAP2/TNF/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/LTA/PTPRC/B2M/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4 132
GO:0048002 antigen processing and presentation of peptide antigen 88/3662 128/15509 2.33411e-27 2.89337e-25 1.74002e-25 HFE/SLC11A1/CD74/FCGR2B/PYCARD/MR1/ERAP2/TAP1/CALR/HLA-DQB1/HLA-DQA1/HLA-DOA/TAP2/HLA-E/HLA-G/TAP2/HLA-DQB1/TAP1/TAP2/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/TAP2/HLA-B/HLA-DQA1/HLA-DPB1/HLA-A/TAP1/HLA-A/HLA-B/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/TAP2/TAP1/HLA-DPB1/HLA-A/TAP1/HLA-DRA/HLA-DQA1/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/TAP1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/TAPBP/HLA-DQB1/HLA-DQA1/HLA-B/TAP2/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/TAP2/HLA-DPB1/HLA-DQA1/B2M/HLA-G/HLA-DRA 88
GO:1902107 positive regulation of leukocyte differentiation 112/3662 185/15509 4.48692e-27 5.34806e-25 3.21623e-25 BAD/CD4/BTK/TYROBP/CD74/RUNX3/ARID1B/FOXP3/AP3D1/RHOA/CBFB/GLI2/ACTB/IL4R/PTPRC/IL12RB1/SMARCB1/XBP1/ACIN1/IL7/TGFB1/GATA3/ZMIZ1/SMARCD2/ZBTB16/MDK/IFNG/NEDD9/IL17A/IL12B/IL4/IL5/BCL6/CD86/ZAP70/ID2/ARID1A/MYB/FOXO3/CD80/SOX4/TNFSF9/LIF/RARA/AP3B1/NOTCH2/IL2RA/HLX/IL10/RB1/DUSP10/IL2RG/IL18/POU4F2/POU4F1/PRKCA/KLF10/MMP14/RUNX1/TGFBR2/PF4/SLC9B2/SHH/SYK/BRD7/RAG1/FADD/RHOH/INPP5D/LGALS9/FOS/CCL19/KAT5/STAT5B/CTNNBIP1/KLHL25/CSF1/SOCS1/ZFP36L1/LILRB4/ARID2/HMGB1/PNP/CR1/TNF/HLA-G/HLA-DRA/TNF/HLA-G/TNF/HLA-DRA/TNF/TNF/TNF/HLA-DRA/TNF/HLA-G/TNF/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/PRKDC/PTPRC/SMARCB1/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4/INPP5D 112
GO:1903708 positive regulation of hemopoiesis 112/3662 185/15509 4.48692e-27 5.34806e-25 3.21623e-25 BAD/CD4/BTK/TYROBP/CD74/RUNX3/ARID1B/FOXP3/AP3D1/RHOA/CBFB/GLI2/ACTB/IL4R/PTPRC/IL12RB1/SMARCB1/XBP1/ACIN1/IL7/TGFB1/GATA3/ZMIZ1/SMARCD2/ZBTB16/MDK/IFNG/NEDD9/IL17A/IL12B/IL4/IL5/BCL6/CD86/ZAP70/ID2/ARID1A/MYB/FOXO3/CD80/SOX4/TNFSF9/LIF/RARA/AP3B1/NOTCH2/IL2RA/HLX/IL10/RB1/DUSP10/IL2RG/IL18/POU4F2/POU4F1/PRKCA/KLF10/MMP14/RUNX1/TGFBR2/PF4/SLC9B2/SHH/SYK/BRD7/RAG1/FADD/RHOH/INPP5D/LGALS9/FOS/CCL19/KAT5/STAT5B/CTNNBIP1/KLHL25/CSF1/SOCS1/ZFP36L1/LILRB4/ARID2/HMGB1/PNP/CR1/TNF/HLA-G/HLA-DRA/TNF/HLA-G/TNF/HLA-DRA/TNF/TNF/TNF/HLA-DRA/TNF/HLA-G/TNF/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/PRKDC/PTPRC/SMARCB1/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4/INPP5D 112
GO:0045824 negative regulation of innate immune response 91/3662 138/15509 3.65018e-26 4.26865e-24 2.56709e-24 GRN/LILRB1/TNFAIP3/ARG1/ARRB2/DUSP10/PARP1/CD96/NLRX1/LGALS9/SERPINB9/BANF1/PTPN2/A2M/MICA/YTHDF3/KIR2DL4/CR1/ZDHHC18/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 91
GO:0030099 myeloid cell differentiation 182/3662 377/15509 3.86899e-26 4.44074e-24 2.67058e-24 SLC4A1/KMT2E/PAF1/SCIN/PAFAH1B1/CD4/TYROBP/LTF/UFL1/CD74/ALAS1/HMGB3/GAB2/KCNQ1/HIPK2/SPI1/CBFB/TFE3/CDC42/WDR1/ATP6AP1/HOXA9/OSTM1/PIR/CEBPE/MYH9/ACIN1/DHRS2/NFKBIA/MMP9/RASSF2/GATA1/SFRP1/ERCC2/LILRB1/TGFB1/KLF1/JAK3/HOXA5/GATA3/SH3PXD2A/CSF3/ZBTB16/CD81/SLC11A2/SH2B3/IFNG/NEDD9/MAPK14/RHAG/IL17A/HSPA9/IL12B/IL4/IL5/SMAD5/BCL6/STAT1/ID2/EPAS1/MPL/MYB/FOXO3/PTBP3/CSF3R/PTK2B/IAPP/INHBA/THRA/CCR7/PRMT1/ZFP36/LIF/LRRC17/CBFA2T3/EPO/NDFIP1/RARA/PIAS3/AP3B1/TSPAN2/NOTCH2/ABCB10/IREB2/TLR4/IRF4/RB1/CUL4A/SKIC8/IRF8/TNFRSF11A/APP/EPHA2/ARNT/DYRK3/PARP1/LBR/MEIS1/TCTA/PIK3R1/PURB/NCAPG2/POU4F2/POU4F1/PRKCA/GABPA/KLF10/KIT/ALAS2/DMTN/RUNX1/ZNF385A/TAL1/RBM15/TGFBR2/PF4/BAP1/SLC9B2/CASP3/TLR3/CSF2/SFXN1/TNFRSF11B/EPB42/FADD/RBPJ/INPP5D/AHSP/FOS/CEBPB/CCL19/RARG/ESRRA/GPR137/STAT5B/PTPN2/JUN/FAM20C/MAF/CTNNBIP1/PTPN11/ADIPOQ/CSF1R/ANXA2/CSF1/CIB1/SOCS1/ZFP36L1/CDIN1/LILRB4/PRTN3/SRC/NCOA6/MTOR/L3MBTL3/MAFB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/CEBPA/PRKDC/H4C15/H4C14/H4C12/B2M/LILRB1/LILRB4/LILRB1/H4C5/LILRB1/H4C4/PRTN3/LILRB1/LILRB4/LILRB4/INPP5D 182
GO:0031348 negative regulation of defense response 152/3662 294/15509 6.43371e-26 7.25021e-24 4.36015e-24 IGF1/HGF/TNFRSF1B/GRN/FOXP3/SIRT2/VPS35/FCGR2B/MKRN2/ARG2/PTPRC/HCK/RIOK3/ACP5/MEFV/LILRB1/HAMP/GATA3/C1QBP/MDK/MVK/PPARD/MAPK14/IL12B/IL4/ASH1L/TNFAIP3/ARG1/TEK/NR1D1/ZFP36/APOE/NDFIP1/SYT11/IL2RA/NT5E/IL10/CCN3/CYP19A1/PPM1B/TARBP2/RB1/FURIN/ARRB2/SOD1/DUSP10/PARP1/PLK2/CD96/PSMB4/NLRX1/PRKCD/GPER1/SYK/HTRA1/NOD2/LGALS9/SERPINB9/BANF1/PTPN2/A2M/ADIPOQ/MICA/YTHDF3/CNR2/KIR2DL4/PCBP2/SRC/ELANE/CR1/ZDHHC18/HLA-E/HLA-G/MICB/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/MICB/HLA-B/HLA-E/HLA-A/MICB/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICB/MICA/MICB/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/MICB/PTPRC/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/ELANE/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/ITCH 152
GO:0002831 regulation of response to biotic stimulus 187/3662 396/15509 2.2762e-25 2.51927e-23 1.51504e-23 TYROBP/LTF/BIRC3/GRN/FOXP3/CYBA/PUM2/SPI1/SIRT2/FCGR2B/UBE2K/XRCC5/ARG2/ZMPSTE24/MAVS/IL12RB1/HCK/RIOK3/TLR8/N4BP1/PYCARD/LILRB1/NOD1/AHR/C1QBP/HPX/IL17A/IL12B/IL4/WNT5A/STAT1/CD160/TNFAIP3/ARG1/IL1B/IRF3/NECTIN2/APOE/TRAF3/TRIM5/POLR3F/SYT11/PTPN22/CD36/AKIRIN2/TLR4/DDX60/PPM1B/HERC5/IL21/SLC15A4/TARBP2/ARRB2/DUSP10/PARP1/NONO/MR1/BMP6/CD96/PRKCA/GBP5/APPL1/NLRX1/SYK/MBL2/HTRA1/TRIM44/NOD2/PRDX2/FADD/POLR3D/LGALS9/TRIM56/CD14/SERPINB9/STAT5B/LEP/BANF1/PTPN2/A2M/PTPN11/PAK2/MICA/SIGIRR/SOCS1/YTHDF3/HEXIM1/CARD9/PLSCR1/KIR2DL4/HMGB1/CD55/DAPK1/PCBP2/SRC/CR1/ZDHHC18/HLA-E/HLA-G/MICB/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/NCR3/HLA-A/HLA-A/MICB/HLA-B/HLA-E/NCR3/HLA-A/MICB/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICB/MICA/MICB/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/MICB/PRKDC/LSM14A/CCL5/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/CCL5/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/ITCH 187
GO:0019884 antigen processing and presentation of exogenous antigen 75/3662 105/15509 3.56882e-25 3.88062e-23 2.33374e-23 CD74/AP3D1/FCGR2B/PSME1/AP3B1/MR1/CD1A/CD1C/CD1B/TAP1/HLA-DQB1/HLA-DQA1/HLA-DOA/TAP2/HLA-E/TAP2/HLA-DQB1/TAP1/TAP2/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-E/HLA-A/HLA-A/HLA-DPB1/TAP2/HLA-DQA1/HLA-DPB1/HLA-A/TAP1/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/TAP2/TAP1/HLA-DPB1/HLA-A/TAP1/HLA-DRA/HLA-DQA1/TAP2/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/HLA-E/TAP1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/TAP2/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-A/HLA-DQA1/HLA-E/HLA-DPB1/HLA-DQA1/TAP2/HLA-DPB1/HLA-DQA1/B2M/HLA-DRA 75
GO:0032102 negative regulation of response to external stimulus 205/3662 453/15509 9.25024e-25 9.885e-23 5.94466e-23 CD9/LTF/IGF1/HGF/TNFRSF1B/GRN/FOXP3/SIRT2/VPS35/NUCB2/FCGR2B/ST6GAL1/MKRN2/ARG2/PTPRC/APOH/ANGPT2/PDGFB/CHD8/HCK/RIOK3/ACP5/MEFV/PLAT/LILRB1/HAMP/SERPINE1/DVL1/GATA3/WNT3/C1QBP/CCL2/MDK/MVK/SH2B3/PPARD/MAPK14/IL12B/IL4/WNT5A/ASH1L/PADI2/NENF/TNFAIP3/ARG1/SPP1/TEK/NR1D1/ZFP36/APOE/NDFIP1/SYT11/IL2RA/PDGFRA/NT5E/SERPINE2/IL10/CCN3/KIAA0319/THBS1/CYP19A1/PPM1B/FGF2/TARBP2/RB1/BBS4/FURIN/ADAMTS18/ARRB2/SOD1/DUSP10/PARP1/SLIT2/PLK2/NOTCH1/CD96/CXCL13/PSMB4/NLRX1/WNT4/PRKCD/GPER1/NOS3/SYK/HTRA1/NOD2/PRDX2/SEMA4C/LGALS9/SEMA3E/SERPINB9/FGG/FGA/LEP/BANF1/PTPN2/A2M/F2/ADIPOQ/RGMA/ANXA2/MICA/SIGIRR/YTHDF3/CNR2/KIR2DL4/PCBP2/SRC/ELANE/DPP4/CR1/ZDHHC18/TNF/HLA-E/HLA-G/TNF/MICB/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/TNF/HLA-A/HLA-A/MICB/HLA-B/HLA-E/HLA-A/MICB/TNF/TNF/HLA-B/TNF/HLA-A/HLA-E/TNF/HLA-E/HLA-G/MICB/MICA/MICB/HLA-A/HLA-B/TNF/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/MICB/PTPRC/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/MIF/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/ELANE/WNT3/WNT3/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/PTEN/ITCH 205
GO:0032943 mononuclear cell proliferation 157/3662 314/15509 1.01678e-24 1.06813e-22 6.42357e-23 CD38/BTK/TYROBP/CD22/IGF1/SLC11A1/CD74/BTN3A1/TNFRSF1B/FOXP3/FCGR2B/ST6GAL1/ARG2/PTPRC/BAX/P2RX7/IL12RB1/ABL1/CD40/NFATC2/ELF4/CD40LG/PYCARD/IL7/LILRB1/IL27RA/CLC/CD79A/JAK3/PIK3CG/AHR/TNFSF8/PPP3CB/CD81/CCND3/IL12B/IL4/IL5/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/MPL/ARG1/GPAM/HELLS/CD80/FLT3/PKN1/CDKN1A/IL1B/TNFSF9/CD70/RAC2/TWSG1/FOXJ1/EPO/NDFIP1/EPHB2/SFTPD/PTPN22/IL2RA/IL6/IL10/TLR4/IL21/SLC7A1/ARMC5/TNFRSF21/MSN/IL18/MS4A1/TNFRSF13C/ICOSLG/WNT4/VCAM1/TGFBR2/SPTA1/CTLA4/PRKCD/CASP3/SHH/SYK/LMO1/PRDX2/FADD/INPP5D/LGALS9/BCL2L1/CEBPB/CCL19/STAT5B/LEP/GLMN/RAG2/CD19/CD28/CSF1/LILRB4/ZP3/HMGB1/CD55/PDCD1LG2/IFNA1/PNP/CR1/HLA-E/HLA-G/PSMB10/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-DPB1/HLA-G/HLA-DPB1/TNFRSF13B/PTPRC/CCL5/CD24/CCL5/LILRB1/LILRB4/HLA-G/LILRB1/MIF/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 157
GO:0045088 regulation of innate immune response 146/3662 285/15509 2.03067e-24 2.09769e-22 1.26151e-22 TYROBP/BIRC3/GRN/SPI1/FCGR2B/UBE2K/XRCC5/MAVS/HCK/RIOK3/TLR8/N4BP1/PYCARD/LILRB1/HPX/IL12B/WNT5A/CD160/TNFAIP3/ARG1/IRF3/NECTIN2/APOE/TRIM5/POLR3F/PTPN22/AKIRIN2/TLR4/IL21/SLC15A4/ARRB2/DUSP10/PARP1/NONO/CD96/GBP5/APPL1/NLRX1/SYK/MBL2/NOD2/FADD/POLR3D/LGALS9/TRIM56/SERPINB9/STAT5B/LEP/BANF1/PTPN2/A2M/PTPN11/PAK2/MICA/SOCS1/YTHDF3/HEXIM1/CARD9/PLSCR1/KIR2DL4/HMGB1/SRC/CR1/ZDHHC18/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/MICA/HLA-G/HLA-E/MICA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/PRKDC/LSM14A/CCL5/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/CCL5/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/LILRB1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 146
GO:0046651 lymphocyte proliferation 154/3662 308/15509 2.86832e-24 2.9144e-22 1.75267e-22 CD38/BTK/TYROBP/CD22/IGF1/SLC11A1/CD74/BTN3A1/TNFRSF1B/FOXP3/FCGR2B/ARG2/PTPRC/BAX/P2RX7/IL12RB1/ABL1/CD40/NFATC2/ELF4/CD40LG/PYCARD/IL7/LILRB1/IL27RA/CLC/CD79A/JAK3/PIK3CG/AHR/TNFSF8/PPP3CB/CD81/CCND3/IL12B/IL4/IL5/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/MPL/ARG1/GPAM/HELLS/CD80/FLT3/PKN1/CDKN1A/IL1B/TNFSF9/CD70/RAC2/TWSG1/FOXJ1/EPO/NDFIP1/EPHB2/SFTPD/PTPN22/IL2RA/IL6/IL10/TLR4/IL21/SLC7A1/ARMC5/TNFRSF21/MSN/IL18/MS4A1/TNFRSF13C/ICOSLG/WNT4/VCAM1/TGFBR2/SPTA1/CTLA4/PRKCD/CASP3/SHH/SYK/LMO1/PRDX2/FADD/INPP5D/LGALS9/CEBPB/CCL19/STAT5B/LEP/GLMN/RAG2/CD19/CD28/LILRB4/ZP3/HMGB1/CD55/PDCD1LG2/IFNA1/PNP/CR1/HLA-E/HLA-G/PSMB10/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-DPB1/HLA-G/HLA-DPB1/TNFRSF13B/PTPRC/CCL5/CD24/CCL5/LILRB1/LILRB4/HLA-G/LILRB1/MIF/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 154
GO:0043068 positive regulation of programmed cell death 212/3662 479/15509 4.78351e-24 4.78197e-22 2.87579e-22 BAD/MAP3K9/SCIN/NOX1/TYROBP/FAS/TNFRSF1B/BAK1/GRN/AIFM2/CCAR1/NGFR/DDX20/MAP2K4/RHOA/HYAL2/SIRT2/TP63/TP73/PTPRC/STK17B/BAX/MMP2/DNM1L/P2RX7/ZNF268/ABL1/GADD45B/MMP9/CD40/MYBL2/BMP7/EEF1A2/RASSF2/SRPX/CD40LG/PYCARD/SFRP1/FCER2/TLE5/LILRB1/PDCD5/GSK3A/GSDME/HOXA5/CASP2/SFRP4/TGFBR1/MAPK8/SEPTIN4/C1QBP/CCL2/MAP2K6/CTSC/ZBTB16/VDR/IFNG/IL12B/PDGFRB/BCL6/WNT5A/ITGA4/PARK7/MFN2/GADD45A/CD160/FASLG/FOXO3/PTPA/IFIT2/CLU/TNFRSF10B/TNFRSF8/IAPP/TNFSF10/INHBA/NR4A1/CDKN1A/SOX4/EEF1E1/RBCK1/BMP2/PLAGL2/BECN1/STYXL1/IRF5/ALDH1A2/AKAP12/TOP2A/MYBBP1A/SERINC3/BTG1/RNF122/NOTCH2/APC/HRK/SRPK2/ITM2C/IL6/IL10/TFAP2A/MTCH1/THBS1/CYP1B1/ARRB2/SMAD4/PMAIP1/SOD1/CCN1/ADCY10/TP53BP2/PARP1/RHOB/TEX261/ARL6IP5/SLIT2/IGFBP3/GSN/NOTCH1/ITGB1/FOXO1/POU4F2/POU4F1/BCL2L11/PRMT2/RPL26/OMA1/PEA15/ATF3/CAPN2/FRZB/INHBB/ERCC3/CTLA4/RYBP/PRKCD/CASP3/TLR3/STK17A/GPER1/CDK5/TP53INP1/SYK/HTRA1/SLC27A4/FADD/INPP5D/LGALS9/PRELID1/ITGAM/KLF11/RARG/ATP2A2/LEP/DDIT3/PTPN2/FOSL1/CDK5R1/JUN/PAK2/PRF1/CXCR2/NQO1/ADIPOQ/PHLDA2/RBM10/CHEK2/FZD9/HMGB1/AKR1C3/TRPV1/DAPK1/IGF2R/SRC/MAP3K5/ATG7/NTRK1/TGM2/TNF/HLA-G/TNF/HLA-G/FIS1/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/HLA-G/LTA/TNF/HLA-G/HLA-G/HLA-G/HLA-G/LTA/PRKDC/PTPRC/TXNIP/CCL5/CCL5/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1/INPP5D/SQSTM1/PTEN 212
GO:0042098 T cell proliferation 126/3662 233/15509 5.68349e-24 5.59147e-22 3.36261e-22 IGF1/SLC11A1/BTN3A1/TNFRSF1B/FOXP3/ARG2/PTPRC/BAX/P2RX7/IL12RB1/ABL1/ELF4/CD40LG/PYCARD/LILRB1/IL27RA/CLC/JAK3/PIK3CG/TNFSF8/PPP3CB/CD81/CCND3/IL12B/IL4/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/ARG1/GPAM/CD80/IL1B/TNFSF9/CD70/RAC2/TWSG1/FOXJ1/EPO/NDFIP1/SFTPD/PTPN22/IL2RA/IL6/IL10/IL21/SLC7A1/ARMC5/TNFRSF21/MSN/IL18/TNFRSF13C/ICOSLG/WNT4/VCAM1/TGFBR2/SPTA1/CTLA4/CASP3/SHH/SYK/LMO1/PRDX2/FADD/LGALS9/CEBPB/CCL19/STAT5B/LEP/GLMN/CD28/LILRB4/ZP3/HMGB1/CD55/PDCD1LG2/PNP/CR1/HLA-E/HLA-G/PSMB10/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-DPB1/HLA-G/HLA-DPB1/PTPRC/CCL5/CD24/CCL5/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/PTEN/ITCH 126
GO:0019883 antigen processing and presentation of endogenous antigen 55/3662 67/15509 6.43186e-24 6.22885e-22 3.74592e-22 HFE/CD74/CD1A/CD1C/CD1B/ERAP2/TAP1/TAP2/HLA-E/HLA-G/TAP2/TAP1/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/TAP1/HLA-A/HLA-B/HLA-E/TAP2/TAP1/HLA-A/TAP1/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/TAP1/HLA-A/TAPBP/HLA-B/TAP2/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/B2M/HLA-G/HLA-DRA 55
GO:0002824 positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 94/3662 152/15509 6.71764e-24 6.40553e-22 3.85217e-22 CD4/BTK/SLC11A1/FOXP3/TBX21/MLH1/PTPRC/P2RX7/MSH2/IL12RB1/CD40/FCER2/IL27RA/TGFB1/EXOSC3/GATA3/NSD2/HPX/CD81/IL12B/IL4/SHLD2/IL1B/C3/NECTIN2/IL6/IL18/MR1/CD1A/CD1C/CD1B/TNFSF13/NOD2/FADD/CD28/CARD9/ZP3/CD55/TAP2/TNF/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/LTA/HLA-A/HLA-DRA/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-G/LTA/HLA-A/HLA-B/TAP2/TNF/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/LTA/PTPRC/B2M/HLA-G/HLA-DRA 94
GO:0002821 positive regulation of adaptive immune response 96/3662 157/15509 7.50189e-24 7.04496e-22 4.23671e-22 CD4/BTK/SLC11A1/FOXP3/TBX21/MLH1/PTPRC/P2RX7/MSH2/IL12RB1/CD40/PYCARD/FCER2/IL27RA/TGFB1/EXOSC3/GATA3/NSD2/HPX/CD81/IL12B/IL4/SHLD2/IL1B/C3/NECTIN2/AKIRIN2/IL6/IL18/MR1/CD1A/CD1C/CD1B/TNFSF13/NOD2/FADD/CD28/CARD9/ZP3/CD55/TAP2/TNF/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/TNF/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/LTA/TNF/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/LTA/HLA-A/HLA-DRA/TNF/TAP2/TNF/HLA-B/TNF/HLA-DRA/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-G/LTA/HLA-A/HLA-B/TAP2/TNF/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/LTA/PTPRC/B2M/HLA-G/HLA-DRA 96
GO:0032103 positive regulation of response to external stimulus 212/3662 481/15509 9.13475e-24 8.45033e-22 5.08188e-22 BTK/TYROBP/CD74/GRN/CASR/CYBA/PUM2/F7/KARS1/SPI1/HYAL2/FGFR1/UBE2K/XRCC5/DNM1L/MAVS/APOH/OSM/PDGFB/NFKBIA/HCK/RIOK3/TLR8/ABCC1/PYCARD/PLAT/PRKD2/TGFB1/PIK3CG/PTN/MET/NOD1/HSPB1/SERPINE1/CREB3/CXCL12/C1QBP/CTSC/HPX/MDK/CD81/IFNG/NEDD9/IL17A/SMOC2/IL12B/IL4/PDGFRB/WNT5A/SNX4/PARK7/CD160/ARG1/VAMP8/PGF/PTK2B/CXCR4/IL1B/C3/CCR7/IRF3/KDR/RAC2/NECTIN2/TRIM5/POLR3F/AKIRIN2/IL6/TLR4/CCL21/DDX60/THBS1/IL21/FGF2/SLC15A4/IGF1R/TNFRSF11A/APP/SLIT2/TPBG/NONO/VEGFC/IL18/BMP6/PRKCA/GBP5/CXCL13/IL6R/CAMK2N1/TLR3/SYK/MBL2/NOD2/FADD/CX3CR1/POLR3D/LGALS9/PTK2/CXCL8/TRIM56/CD14/S1PR1/SCG2/CEBPB/IL16/CCL19/STAT5B/LPL/CD28/CALR/F2/PAK2/CXCR2/CSF1R/CCR4/CSF1/HEXIM1/CARD9/PLSCR1/ZP3/KIR2DL4/HMGB1/TLR7/CD47/SRC/TNF/HLA-E/HLA-G/TMSB4X/TNF/HLA-E/HLA-G/ZNF580/NCR3/LTA/TNF/HLA-E/NCR3/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/HLA-G/LTA/TNF/HLA-G/HLA-E/HLA-G/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/LTA/NEAT1/CEBPA/NAIP/PRKDC/LSM14A/CCL5/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/CCL5/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/CCL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/CCL4/KIR2DL4/KIR2DL4/HLA-G/NAIP/MIF/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/CCL4/KIR2DL4/KIR2DL4/ABCC1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/NAIP/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 212
GO:0002483 antigen processing and presentation of endogenous peptide antigen 51/3662 60/15509 1.16583e-23 1.06262e-21 6.39038e-22 HFE/ERAP2/TAP1/TAP2/HLA-E/HLA-G/TAP2/TAP1/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/TAP1/HLA-A/HLA-B/HLA-E/TAP2/TAP1/HLA-A/TAP1/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/TAP1/HLA-A/TAPBP/HLA-B/TAP2/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/B2M/HLA-G/HLA-DRA 51
GO:0019724 B cell mediated immunity 114/3662 203/15509 1.2356e-23 1.10989e-21 6.67471e-22 BTK/CD74/PARP3/FOXP3/FCGR2B/TBX21/MLH1/IL4R/PTPRC/MSH2/CD40/TLR8/CD40LG/IL21R/NBN/FCER2/IL27RA/TGFB1/EXOSC3/C1QBP/NSD2/HPX/CD81/AICDA/IL4/BCL6/CLU/SHLD2/CD70/C3/FOXJ1/NECTIN2/NDFIP1/IL10/SLC15A4/TNFSF13/PRKCD/MBL2/NOD2/INPP5D/LIG4/CD19/CD28/HLA-DQB1/CARD9/ZP3/CD55/HLA-DQA1/CR1/HLA-DOA/TNF/HLA-E/HLA-G/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-E/HLA-G/HLA-DPB1/HLA-DQA1/HLA-DPB1/LTA/TNF/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/LTA/HLA-DPB1/HLA-DRA/HLA-DQA1/TNF/TNF/TNF/HLA-DRA/HLA-E/HLA-DPB1/TNF/HLA-E/LTA/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/LTA/HLA-DQA1/HLA-DQB1/HLA-DQA1/TNF/HLA-G/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-G/HLA-G/HLA-DQA1/HLA-E/HLA-DPB1/HLA-G/HLA-DQA1/HLA-DPB1/LTA/HLA-DQA1/PTPRC/B2M/HLA-G/HLA-DRA/INPP5D 114
GO:0032944 regulation of mononuclear cell proliferation 135/3662 259/15509 1.38449e-23 1.22587e-21 7.37214e-22 CD38/BTK/TYROBP/CD22/IGF1/CD74/TNFRSF1B/FOXP3/FCGR2B/ST6GAL1/ARG2/PTPRC/IL12RB1/CD40/NFATC2/CD40LG/PYCARD/IL7/LILRB1/IL27RA/CLC/JAK3/AHR/TNFSF8/CD81/IL12B/IL4/IL5/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/MPL/ARG1/GPAM/CD80/PKN1/CDKN1A/IL1B/TNFSF9/CD70/RAC2/TWSG1/FOXJ1/EPO/NDFIP1/EPHB2/SFTPD/PTPN22/IL2RA/IL6/IL10/TLR4/IL21/SLC7A1/TNFRSF21/IL18/TNFRSF13C/ICOSLG/VCAM1/TGFBR2/SPTA1/CTLA4/CASP3/SHH/SYK/LMO1/FADD/INPP5D/LGALS9/BCL2L1/CEBPB/CCL19/STAT5B/LEP/GLMN/CD28/CSF1/LILRB4/ZP3/HMGB1/CD55/PDCD1LG2/PNP/CR1/HLA-E/HLA-G/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-DPB1/HLA-G/HLA-DPB1/TNFRSF13B/PTPRC/CCL5/CD24/CCL5/LILRB1/LILRB4/HLA-G/LILRB1/MIF/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 135
GO:0070661 leukocyte proliferation 166/3662 346/15509 1.44511e-23 1.26152e-21 7.58656e-22 CD38/BTK/TYROBP/CD22/IGF1/SLC11A1/CD74/BTN3A1/TNFRSF1B/FOXP3/FCGR2B/ST6GAL1/ARG2/PTPRC/BAX/P2RX7/IL5RA/IL12RB1/ABL1/CD40/NFATC2/ELF4/CD40LG/PYCARD/IL7/LILRB1/IL27RA/CLC/CD79A/JAK3/PIK3CG/AHR/TNFSF8/PPP3CB/CD81/CCND3/IL12B/IL4/IL5/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/MPL/TNFAIP3/ARG1/GPAM/HELLS/CLU/CD80/FLT3/PKN1/CDKN1A/IL1B/TNFSF9/CD70/RAC2/TWSG1/FOXJ1/EPO/NDFIP1/EPHB2/SFTPD/PTPN22/IL2RA/IL6/IL10/TLR4/IL21/SLC7A1/ARMC5/TNFRSF21/MSN/IL18/HHEX/MS4A1/KIT/TNFRSF13C/ICOSLG/WNT4/VCAM1/TGFBR2/SPTA1/CTLA4/BAP1/PRKCD/CASP3/CSF2/SHH/SYK/LMO1/PRDX2/FADD/INPP5D/LGALS9/PTK2/BCL2L1/CEBPB/CCL19/STAT5B/LEP/GLMN/RAG2/CD19/CD28/CSF1R/CSF1/LILRB4/ZP3/HMGB1/CD55/PDCD1LG2/IFNA1/PNP/CR1/HLA-E/HLA-G/PSMB10/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-DPB1/HLA-G/HLA-DPB1/TNFRSF13B/PTPRC/CCL5/CD24/CCL5/LILRB1/LILRB4/HLA-G/LILRB1/MIF/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 166
GO:0002717 positive regulation of natural killer cell mediated immunity 64/3662 86/15509 2.73975e-23 2.35847e-21 1.41834e-21 IL12B/CD160/NECTIN2/IL21/STAT5B/KIR2DL4/HLA-E/HLA-G/HLA-E/HLA-G/NCR3/HLA-E/NCR3/HLA-E/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 64
GO:0043065 positive regulation of apoptotic process 206/3662 467/15509 3.56866e-23 3.02994e-21 1.82215e-21 BAD/MAP3K9/SCIN/NOX1/TYROBP/FAS/TNFRSF1B/BAK1/GRN/AIFM2/CCAR1/NGFR/DDX20/MAP2K4/RHOA/HYAL2/SIRT2/TP63/TP73/PTPRC/STK17B/BAX/MMP2/DNM1L/P2RX7/ZNF268/ABL1/GADD45B/MMP9/CD40/MYBL2/BMP7/EEF1A2/RASSF2/SRPX/CD40LG/PYCARD/SFRP1/TLE5/LILRB1/PDCD5/GSK3A/GSDME/HOXA5/CASP2/SFRP4/TGFBR1/MAPK8/SEPTIN4/C1QBP/CCL2/MAP2K6/CTSC/ZBTB16/VDR/IFNG/IL12B/PDGFRB/BCL6/WNT5A/ITGA4/PARK7/MFN2/GADD45A/CD160/FASLG/FOXO3/PTPA/IFIT2/CLU/TNFRSF10B/TNFRSF8/IAPP/TNFSF10/INHBA/NR4A1/SOX4/EEF1E1/RBCK1/BMP2/PLAGL2/BECN1/STYXL1/IRF5/ALDH1A2/AKAP12/TOP2A/MYBBP1A/SERINC3/BTG1/RNF122/NOTCH2/APC/HRK/SRPK2/ITM2C/IL6/IL10/TFAP2A/MTCH1/THBS1/CYP1B1/ARRB2/SMAD4/PMAIP1/SOD1/CCN1/ADCY10/TP53BP2/RHOB/TEX261/ARL6IP5/SLIT2/IGFBP3/GSN/NOTCH1/ITGB1/FOXO1/POU4F2/POU4F1/BCL2L11/PRMT2/RPL26/OMA1/PEA15/ATF3/CAPN2/FRZB/INHBB/ERCC3/CTLA4/RYBP/PRKCD/CASP3/TLR3/STK17A/GPER1/CDK5/TP53INP1/HTRA1/SLC27A4/FADD/INPP5D/LGALS9/PRELID1/ITGAM/KLF11/RARG/ATP2A2/LEP/DDIT3/PTPN2/FOSL1/CDK5R1/JUN/PAK2/CXCR2/NQO1/ADIPOQ/PHLDA2/RBM10/CHEK2/FZD9/HMGB1/AKR1C3/TRPV1/DAPK1/IGF2R/SRC/MAP3K5/ATG7/TGM2/TNF/HLA-G/TNF/HLA-G/FIS1/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/HLA-G/LTA/TNF/HLA-G/HLA-G/HLA-G/HLA-G/LTA/PRKDC/PTPRC/TXNIP/CCL5/CCL5/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1/INPP5D/SQSTM1/PTEN 206
GO:0002456 T cell mediated immunity 92/3662 150/15509 4.76025e-23 3.98703e-21 2.39773e-21 HFE/TNFRSF1B/FOXP3/FCGR2B/TBX21/PTPRC/P2RX7/ICAM1/IL12RB1/SMAD7/LILRB1/CLC/AHR/GATA3/PPP3CB/CTSC/CD81/IL12B/IL4/ARG1/IL1B/CD70/NECTIN2/IL6/IL18/MR1/CD8A/CD1A/CD1C/CD1B/NOD2/FADD/PRF1/MICA/BTN3A2/LILRB4/ZP3/HMGB1/CD55/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/TAP2/MICA/HLA-G/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/PTPRC/B2M/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4 92
GO:0002709 regulation of T cell mediated immunity 82/3662 127/15509 8.43779e-23 6.97299e-21 4.19343e-21 HFE/TNFRSF1B/FOXP3/FCGR2B/TBX21/PTPRC/P2RX7/IL12RB1/SMAD7/LILRB1/CLC/AHR/GATA3/PPP3CB/CD81/IL12B/IL4/ARG1/IL1B/NECTIN2/IL6/IL18/MR1/CD1A/CD1C/CD1B/NOD2/FADD/LILRB4/ZP3/HMGB1/CD55/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-B/TAP2/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/PTPRC/B2M/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4 82
GO:0070663 regulation of leukocyte proliferation 142/3662 283/15509 1.16877e-22 9.53164e-21 5.73216e-21 CD38/BTK/TYROBP/CD22/IGF1/CD74/TNFRSF1B/FOXP3/FCGR2B/ST6GAL1/ARG2/PTPRC/IL5RA/IL12RB1/CD40/NFATC2/CD40LG/PYCARD/IL7/LILRB1/IL27RA/CLC/JAK3/AHR/TNFSF8/CD81/IL12B/IL4/IL5/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/MPL/TNFAIP3/ARG1/GPAM/CD80/PKN1/CDKN1A/IL1B/TNFSF9/CD70/RAC2/TWSG1/FOXJ1/EPO/NDFIP1/EPHB2/SFTPD/PTPN22/IL2RA/IL6/IL10/TLR4/IL21/SLC7A1/TNFRSF21/IL18/HHEX/KIT/TNFRSF13C/ICOSLG/VCAM1/TGFBR2/SPTA1/CTLA4/CASP3/CSF2/SHH/SYK/LMO1/FADD/INPP5D/LGALS9/PTK2/BCL2L1/CEBPB/CCL19/STAT5B/LEP/GLMN/CD28/CSF1R/CSF1/LILRB4/ZP3/HMGB1/CD55/PDCD1LG2/PNP/CR1/HLA-E/HLA-G/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-DPB1/HLA-G/HLA-DPB1/TNFRSF13B/PTPRC/CCL5/CD24/CCL5/LILRB1/LILRB4/HLA-G/LILRB1/MIF/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 142
GO:0002478 antigen processing and presentation of exogenous peptide antigen 68/3662 96/15509 1.30207e-22 1.04808e-20 6.30298e-21 CD74/FCGR2B/TAP1/HLA-DQB1/HLA-DQA1/HLA-DOA/TAP2/HLA-E/TAP2/HLA-DQB1/TAP1/TAP2/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-E/HLA-A/HLA-A/HLA-DPB1/TAP2/HLA-DQA1/HLA-DPB1/HLA-A/TAP1/HLA-A/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/TAP2/TAP1/HLA-DPB1/HLA-A/TAP1/HLA-DRA/HLA-DQA1/TAP2/HLA-DRA/HLA-A/HLA-E/HLA-DPB1/HLA-E/TAP1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-A/HLA-DQB1/HLA-DQA1/TAP2/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-A/HLA-DQA1/HLA-E/HLA-DPB1/HLA-DQA1/TAP2/HLA-DPB1/HLA-DQA1/B2M/HLA-DRA 68
GO:2000774 positive regulation of cellular senescence 49/3662 58/15509 1.5396e-22 1.22339e-20 7.35724e-21 ARG2/EEF1E1/KIR2DL4/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 49
GO:0050670 regulation of lymphocyte proliferation 132/3662 256/15509 1.57958e-22 1.23927e-20 7.45278e-21 CD38/BTK/TYROBP/CD22/IGF1/CD74/TNFRSF1B/FOXP3/FCGR2B/ARG2/PTPRC/IL12RB1/CD40/NFATC2/CD40LG/PYCARD/IL7/LILRB1/IL27RA/CLC/JAK3/AHR/TNFSF8/CD81/IL12B/IL4/IL5/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/MPL/ARG1/GPAM/CD80/PKN1/CDKN1A/IL1B/TNFSF9/CD70/RAC2/TWSG1/FOXJ1/EPO/NDFIP1/EPHB2/SFTPD/PTPN22/IL2RA/IL6/IL10/TLR4/IL21/SLC7A1/TNFRSF21/IL18/TNFRSF13C/ICOSLG/VCAM1/TGFBR2/SPTA1/CTLA4/CASP3/SHH/SYK/LMO1/FADD/INPP5D/LGALS9/CEBPB/CCL19/STAT5B/LEP/GLMN/CD28/LILRB4/ZP3/HMGB1/CD55/PDCD1LG2/PNP/CR1/HLA-E/HLA-G/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-DPB1/HLA-G/HLA-DPB1/TNFRSF13B/PTPRC/CCL5/CD24/CCL5/LILRB1/LILRB4/HLA-G/LILRB1/MIF/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 132
GO:0002573 myeloid leukocyte differentiation 114/3662 208/15509 1.89329e-22 1.46682e-20 8.82123e-21 PAFAH1B1/CD4/TYROBP/LTF/CD74/GAB2/SPI1/TFE3/CDC42/ATP6AP1/OSTM1/PIR/CEBPE/MYH9/ACIN1/DHRS2/MMP9/RASSF2/GATA1/SFRP1/LILRB1/TGFB1/GATA3/SH3PXD2A/CSF3/CD81/IFNG/NEDD9/MAPK14/IL17A/IL12B/IL4/IL5/ID2/IAPP/INHBA/CCR7/LIF/LRRC17/CBFA2T3/NDFIP1/RARA/PIAS3/AP3B1/TSPAN2/NOTCH2/IREB2/TLR4/IRF4/RB1/CUL4A/TNFRSF11A/APP/EPHA2/PARP1/LBR/TCTA/PIK3R1/POU4F2/POU4F1/PRKCA/KLF10/KIT/RUNX1/TAL1/TGFBR2/PF4/BAP1/SLC9B2/TLR3/CSF2/TNFRSF11B/FADD/RBPJ/INPP5D/FOS/CEBPB/CCL19/ESRRA/GPR137/PTPN2/JUN/FAM20C/CTNNBIP1/ADIPOQ/CSF1R/ANXA2/CSF1/SOCS1/ZFP36L1/LILRB4/PRTN3/SRC/MTOR/L3MBTL3/MAFB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/LILRB1/LILRB4/LILRB1/LILRB1/PRTN3/LILRB1/LILRB4/LILRB4/INPP5D 114
GO:1903131 mononuclear cell differentiation 194/3662 436/15509 2.03098e-22 1.55408e-20 9.34594e-21 BAD/TMEM98/CD79B/ST3GAL1/CD4/BTK/CD74/RUNX3/HMGB3/BAK1/ARID1B/FOXP3/PRDM1/AP3D1/SPI1/KLF6/RHOA/CBFB/TCF3/FCGR2B/TBX21/GLI2/ACTB/IL4R/PTPRC/BAX/PIR/HECTD1/MSH2/IL12RB1/ABL1/SMARCB1/XBP1/MYH9/ACIN1/DHRS2/SMAD7/GATA1/CD40LG/SFRP1/IL7/LYL1/LILRB1/CD79A/KDELR1/JAK3/EZH2/TNFSF8/GATA3/PPP3CB/ZMIZ1/SMARCD2/ZBTB16/MDK/POU2AF1/IFNG/AICDA/IL12B/IL4/BCL6/CD86/IL1A/ZAP70/ITGA4/ID2/LEPR/ARID1A/MYB/FOXO3/EGR1/PTK2B/CD80/FLT3/INHBA/SOX4/RUNX2/IL1B/TNFSF9/CCR7/BCL11B/FOXJ1/NDFIP1/RARA/AP3B1/PTPN22/NOTCH2/IL2RA/IL6/HLX/IL10/IRF4/IL21/ARMC5/IRF8/SOD1/DUSP10/DCAF1/PIK3R1/IL2RG/ZEB1/ITGB1/IL18/ZFP36L2/HHEX/MR1/MERTK/CD8A/MS4A1/MMP14/KIT/RUNX1/IL6R/WNT4/VCAM1/TGFBR2/CTLA4/CSF2/SHH/SYK/BRD7/RAG1/PRDX2/FADD/RBPJ/RHOH/INPP5D/LGALS9/PRELID1/FOS/CEBPB/CCL19/KAT5/CCR9/STAT5B/LIG4/LEP/RAG2/PTPN2/CD19/JUN/CD28/CTNNBIP1/CSF1R/KLHL25/CSF1/SOCS1/PBX1/ZFP36L1/LILRB4/FZD9/ARID2/HMGB1/PAX5/PRTN3/IFNA1/ENTPD7/NTRK1/NRARP/MTOR/PNP/CR1/MAFB/HLA-DOA/HLA-G/HLA-DRA/HLA-B/HLA-G/HLA-B/HLA-B/HLA-DRA/HLA-B/HLA-DRA/HLA-G/HLA-B/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/PRKDC/PTPRC/B2M/LILRB1/SMARCB1/LILRB4/HLA-G/LILRB1/LILRB1/HLA-DRA/PRTN3/LILRB1/LILRB4/LILRB4/INPP5D 194
GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I 46/3662 53/15509 2.93731e-22 2.22017e-20 1.33517e-20 HFE/ERAP2/TAP1/TAP2/HLA-E/HLA-G/TAP2/TAP1/TAP2/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/TAP1/HLA-A/HLA-B/HLA-E/TAP2/TAP1/HLA-A/TAP1/TAP2/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/TAP1/HLA-A/TAPBP/HLA-B/TAP2/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/B2M/HLA-G 46
GO:0042129 regulation of T cell proliferation 112/3662 204/15509 3.6903e-22 2.75572e-20 1.65724e-20 IGF1/TNFRSF1B/FOXP3/ARG2/PTPRC/IL12RB1/CD40LG/PYCARD/LILRB1/IL27RA/CLC/JAK3/TNFSF8/CD81/IL12B/IL4/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/ARG1/GPAM/CD80/IL1B/TNFSF9/CD70/RAC2/TWSG1/FOXJ1/EPO/NDFIP1/SFTPD/PTPN22/IL2RA/IL6/IL10/IL21/SLC7A1/TNFRSF21/IL18/TNFRSF13C/ICOSLG/VCAM1/TGFBR2/SPTA1/CTLA4/CASP3/SHH/SYK/LMO1/FADD/LGALS9/CEBPB/CCL19/STAT5B/LEP/GLMN/CD28/LILRB4/ZP3/HMGB1/CD55/PDCD1LG2/PNP/CR1/HLA-E/HLA-G/HLA-E/HLA-A/HLA-A/HLA-G/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-G/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-DPB1/HLA-G/HLA-DPB1/PTPRC/CCL5/CD24/CCL5/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/PTEN/ITCH 112
GO:0001913 T cell mediated cytotoxicity 66/3662 94/15509 1.20059e-21 8.85863e-20 5.32743e-20 FCGR2B/PTPRC/P2RX7/IL12RB1/LILRB1/PPP3CB/CTSC/IL12B/NECTIN2/MR1/CD1A/CD1C/CD1B/FADD/PRF1/MICA/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/MICA/HLA-A/HLA-B/TAP2/MICA/HLA-G/HLA-E/HLA-DRA/MICA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/PTPRC/B2M/LILRB1/HLA-G/LILRB1/LILRB1/HLA-DRA/LILRB1 66
GO:0002237 response to molecule of bacterial origin 158/3662 335/15509 1.54295e-21 1.12508e-19 6.76604e-20 UPF1/MPO/PAF1/SELE/BTK/LTF/SLC11A1/CPS1/TNFRSF1B/FOXP3/SPI1/FGFR2/RHOA/SIRT2/FCGR2B/IL12RB2/OPRK1/APOB/CHMP5/P2RX7/CEBPE/ABL1/XBP1/CTSG/PABPN1/PCK2/NFKBIA/HCK/GATA1/ACP5/PYCARD/LILRB1/TGFB1/HAMP/SERPINE1/MAPK8/CSF3/RPS6KB1/CCL2/CYP27B1/AICDA/PPARD/MAPK14/IL12B/CD86/WNT5A/IL1A/FASLG/TNFAIP3/ARG1/CD80/NR4A1/IL1B/CCR7/NR1D1/IRF3/ZFP36/IRF5/CD68/EPO/ASS1/AKAP12/RARA/TRIM5/EPHB2/PTPN22/CD36/AKIRIN2/EDNRB/IL6/IL10/TLR4/IL18BP/SMAD6/CYP1A1/IRF8/TNFRSF11A/DUSP10/REN/ALAD/NOTCH1/IL18/BMP6/CD96/PRKCA/CXCL13/ADAMTS13/CCR5/GFI1/VCAM1/MAPKAPK2/IL24/CAPN2/PF4/CASP3/CSF2/NOS3/NOD2/PRDX2/CX3CR1/ADAM9/TNIP2/LGALS9/PTAFR/CXCL8/FOS/CD14/PRKCE/CEBPB/RELA/CNP/SELP/F2R/IRAK1/CSF1/PDE4B/SIGIRR/CARD9/CNR2/HMGB1/CD55/SRC/SHPK/ELANE/PDCD1LG2/TAP2/TNF/TAP2/TAP2/TNF/TAP2/LTA/TNF/TAP2/LTA/TNF/TAP2/TNF/TNF/TNF/LTA/LTA/TAP2/TNF/TAP2/LTA/CCL5/CD24/B2M/CCL5/PRPF8/LILRB1/LILRB1/MIF/LILRB1/ELANE/LILRB1/ADAMTS13 158
GO:0045621 positive regulation of lymphocyte differentiation 81/3662 129/15509 2.16932e-21 1.56343e-19 9.40217e-20 BAD/BTK/CD74/RUNX3/ARID1B/FOXP3/AP3D1/RHOA/CBFB/GLI2/ACTB/IL4R/PTPRC/IL12RB1/SMARCB1/XBP1/IL7/GATA3/ZMIZ1/SMARCD2/ZBTB16/MDK/IFNG/IL12B/IL4/BCL6/CD86/ZAP70/ARID1A/MYB/FOXO3/CD80/SOX4/TNFSF9/RARA/AP3B1/IL2RA/HLX/IL10/DUSP10/IL2RG/IL18/MMP14/RUNX1/TGFBR2/SHH/SYK/BRD7/RAG1/RHOH/INPP5D/LGALS9/CCL19/KAT5/STAT5B/KLHL25/SOCS1/LILRB4/ARID2/PNP/CR1/HLA-G/HLA-DRA/HLA-G/HLA-DRA/HLA-DRA/HLA-G/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/PRKDC/PTPRC/SMARCB1/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4/INPP5D 81
GO:0001914 regulation of T cell mediated cytotoxicity 60/3662 82/15509 2.7827e-21 1.98244e-19 1.1922e-19 FCGR2B/PTPRC/P2RX7/IL12RB1/LILRB1/PPP3CB/IL12B/NECTIN2/MR1/CD1A/CD1C/CD1B/FADD/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-B/TAP2/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/PTPRC/B2M/LILRB1/HLA-G/LILRB1/LILRB1/HLA-DRA/LILRB1 60
GO:0001916 positive regulation of T cell mediated cytotoxicity 53/3662 68/15509 4.00402e-21 2.8201e-19 1.69596e-19 PTPRC/P2RX7/IL12RB1/IL12B/NECTIN2/MR1/CD1A/CD1C/CD1B/FADD/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-B/TAP2/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/PTPRC/B2M/HLA-G/HLA-DRA 53
GO:0045582 positive regulation of T cell differentiation 75/3662 116/15509 5.05333e-21 3.51916e-19 2.11636e-19 BAD/CD74/RUNX3/ARID1B/FOXP3/AP3D1/RHOA/CBFB/GLI2/ACTB/IL4R/PTPRC/IL12RB1/SMARCB1/XBP1/IL7/GATA3/ZMIZ1/SMARCD2/ZBTB16/MDK/IFNG/IL12B/IL4/BCL6/CD86/ZAP70/ARID1A/MYB/FOXO3/CD80/SOX4/TNFSF9/RARA/AP3B1/IL2RA/HLX/DUSP10/IL2RG/IL18/RUNX1/TGFBR2/SHH/SYK/BRD7/RAG1/RHOH/LGALS9/CCL19/KAT5/STAT5B/KLHL25/SOCS1/LILRB4/ARID2/PNP/CR1/HLA-G/HLA-DRA/HLA-G/HLA-DRA/HLA-DRA/HLA-G/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/PTPRC/SMARCB1/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4 75
GO:0031343 positive regulation of cell killing 71/3662 107/15509 6.03099e-21 4.15334e-19 2.49775e-19 TYROBP/SPI1/PTPRC/P2RX7/IL12RB1/FCER2/MAPK8/IFNG/IL12B/CD160/ARG1/NECTIN2/IL21/MR1/CD1A/CD1C/CD1B/SYK/FADD/ITGAM/STAT5B/PRF1/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-B/TAP2/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/PTPRC/B2M/HLA-G/HLA-DRA 71
GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway 36/3662 38/15509 9.94809e-21 6.77563e-19 4.07475e-19 TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/HLA-A/TAP2/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-B/TAP2/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/HLA-G 36
GO:0090398 cellular senescence 86/3662 144/15509 1.52336e-20 1.02628e-18 6.17187e-19 WNT16/MAP2K4/SPI1/TP63/SIRT6/ARG2/ZMPSTE24/MAPKAPK5/ABL1/MAPK8/BMPR1A/ZMIZ1/MAP2K6/FBXO5/MAPK14/BCL6/NEK4/ID2/CDKN1A/EEF1E1/HMGA1/BRCA2/IGF1R/ULK3/PLK2/HMGA2/LMNA/PRKCD/TERT/KAT5/HRAS/CALR/NPM1/H2AX/KIR2DL4/MAP3K5/ZNF277/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/AKT3/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/MIF/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/PTEN 86
GO:0031349 positive regulation of defense response 154/3662 330/15509 1.84493e-20 1.22753e-18 7.38213e-19 BTK/TYROBP/GRN/CYBA/KARS1/SPI1/HYAL2/UBE2K/XRCC5/MAVS/OSM/NFKBIA/HCK/RIOK3/TLR8/ABCC1/PYCARD/PIK3CG/NOD1/SERPINE1/CTSC/HPX/MDK/CD81/IFNG/IL17A/IL12B/WNT5A/SNX4/PARK7/CD160/ARG1/VAMP8/IL1B/C3/CCR7/IRF3/NECTIN2/TRIM5/POLR3F/AKIRIN2/IL6/TLR4/IL21/SLC15A4/TNFRSF11A/APP/NONO/IL18/GBP5/CAMK2N1/TLR3/SYK/MBL2/NOD2/FADD/POLR3D/TRIM56/CEBPB/IL16/STAT5B/LPL/CD28/PAK2/HEXIM1/CARD9/PLSCR1/ZP3/KIR2DL4/HMGB1/TLR7/CD47/SRC/TNF/HLA-E/HLA-G/TNF/HLA-E/HLA-G/NCR3/LTA/TNF/HLA-E/NCR3/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/HLA-G/LTA/TNF/HLA-G/HLA-E/HLA-G/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/LTA/NEAT1/CEBPA/NAIP/PRKDC/LSM14A/CCL5/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/CCL5/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/NAIP/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/ABCC1/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/NAIP/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 154
GO:0016064 immunoglobulin mediated immune response 105/3662 193/15509 1.86169e-20 1.22753e-18 7.38213e-19 BTK/CD74/PARP3/FOXP3/FCGR2B/TBX21/MLH1/IL4R/PTPRC/MSH2/CD40/TLR8/CD40LG/IL21R/NBN/FCER2/IL27RA/TGFB1/EXOSC3/C1QBP/NSD2/HPX/CD81/AICDA/IL4/BCL6/CLU/SHLD2/C3/FOXJ1/NECTIN2/NDFIP1/IL10/SLC15A4/TNFSF13/PRKCD/MBL2/NOD2/INPP5D/LIG4/CD19/CD28/HLA-DQB1/CARD9/ZP3/CD55/HLA-DQA1/CR1/HLA-DOA/TNF/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-E/HLA-DPB1/HLA-DQA1/HLA-DPB1/LTA/TNF/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/LTA/HLA-DPB1/HLA-DRA/HLA-DQA1/TNF/TNF/TNF/HLA-DRA/HLA-E/HLA-DPB1/TNF/HLA-E/LTA/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/LTA/HLA-DQA1/HLA-DQB1/HLA-DQA1/TNF/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-DQA1/HLA-E/HLA-DPB1/HLA-DQA1/HLA-DPB1/LTA/HLA-DQA1/PTPRC/B2M/HLA-DRA/INPP5D 105
GO:0045619 regulation of lymphocyte differentiation 106/3662 197/15509 3.72978e-20 2.43339e-18 1.4634e-18 BAD/BTK/CD74/RUNX3/HMGB3/ARID1B/FOXP3/PRDM1/AP3D1/RHOA/CBFB/TBX21/GLI2/ACTB/IL4R/PTPRC/IL12RB1/ABL1/SMARCB1/XBP1/SMAD7/SFRP1/IL7/JAK3/GATA3/ZMIZ1/SMARCD2/ZBTB16/MDK/IFNG/IL12B/IL4/BCL6/CD86/ZAP70/ID2/ARID1A/MYB/FOXO3/CD80/INHBA/SOX4/TNFSF9/FOXJ1/NDFIP1/RARA/AP3B1/IL2RA/HLX/IL10/IRF4/SOD1/DUSP10/IL2RG/ZEB1/IL18/ZFP36L2/MMP14/RUNX1/TGFBR2/CTLA4/SHH/SYK/BRD7/RAG1/PRDX2/RHOH/INPP5D/LGALS9/PRELID1/CCL19/KAT5/STAT5B/RAG2/PTPN2/CD28/KLHL25/SOCS1/ZFP36L1/LILRB4/ARID2/HMGB1/NRARP/PNP/CR1/HLA-DOA/HLA-G/HLA-DRA/HLA-G/HLA-DRA/HLA-DRA/HLA-G/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/PRKDC/PTPRC/SMARCB1/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4/INPP5D 106
GO:0045637 regulation of myeloid cell differentiation 108/3662 203/15509 5.18648e-20 3.34852e-18 2.01374e-18 PAF1/SCIN/CD4/TYROBP/LTF/CD74/HMGB3/SPI1/TFE3/HOXA9/ACIN1/NFKBIA/RASSF2/GATA1/SFRP1/LILRB1/TGFB1/HOXA5/CSF3/ZBTB16/IFNG/NEDD9/MAPK14/IL17A/HSPA9/IL12B/IL4/IL5/STAT1/ID2/MPL/MYB/FOXO3/CSF3R/PTK2B/IAPP/INHBA/PRMT1/ZFP36/LIF/LRRC17/NDFIP1/RARA/PIAS3/NOTCH2/ABCB10/TLR4/RB1/CUL4A/SKIC8/ARNT/MEIS1/TCTA/PIK3R1/PURB/POU4F2/POU4F1/PRKCA/GABPA/KLF10/RUNX1/TAL1/RBM15/PF4/SLC9B2/TLR3/TNFRSF11B/FADD/INPP5D/FOS/CEBPB/RARG/ESRRA/GPR137/STAT5B/PTPN2/CTNNBIP1/ADIPOQ/CSF1/CIB1/ZFP36L1/LILRB4/MTOR/MAFB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/PRKDC/H4C15/H4C14/H4C12/B2M/LILRB1/LILRB4/LILRB1/H4C5/LILRB1/H4C4/LILRB1/LILRB4/LILRB4/INPP5D 108
GO:0030098 lymphocyte differentiation 170/3662 382/15509 8.62681e-20 5.51227e-18 3.31498e-18 BAD/TMEM98/CD79B/ST3GAL1/CD4/BTK/CD74/RUNX3/HMGB3/BAK1/ARID1B/FOXP3/PRDM1/AP3D1/SPI1/KLF6/RHOA/CBFB/TCF3/FCGR2B/TBX21/GLI2/ACTB/IL4R/PTPRC/BAX/HECTD1/MSH2/IL12RB1/ABL1/SMARCB1/XBP1/SMAD7/CD40LG/SFRP1/IL7/LYL1/CD79A/KDELR1/JAK3/EZH2/TNFSF8/GATA3/PPP3CB/ZMIZ1/SMARCD2/ZBTB16/MDK/POU2AF1/IFNG/AICDA/IL12B/IL4/BCL6/CD86/IL1A/ZAP70/ITGA4/ID2/LEPR/ARID1A/MYB/FOXO3/EGR1/PTK2B/CD80/FLT3/INHBA/SOX4/RUNX2/IL1B/TNFSF9/CCR7/BCL11B/FOXJ1/NDFIP1/RARA/AP3B1/PTPN22/NOTCH2/IL2RA/IL6/HLX/IL10/IRF4/IL21/ARMC5/IRF8/SOD1/DUSP10/DCAF1/PIK3R1/IL2RG/ZEB1/ITGB1/IL18/ZFP36L2/HHEX/MR1/MERTK/CD8A/MS4A1/MMP14/KIT/RUNX1/IL6R/WNT4/VCAM1/TGFBR2/CTLA4/SHH/SYK/BRD7/RAG1/PRDX2/FADD/RBPJ/RHOH/INPP5D/LGALS9/PRELID1/CCL19/KAT5/CCR9/STAT5B/LIG4/LEP/RAG2/PTPN2/CD19/CD28/KLHL25/SOCS1/PBX1/ZFP36L1/LILRB4/FZD9/ARID2/HMGB1/PAX5/IFNA1/ENTPD7/NTRK1/NRARP/MTOR/PNP/CR1/MAFB/HLA-DOA/HLA-G/HLA-DRA/HLA-G/HLA-DRA/HLA-DRA/HLA-G/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/PRKDC/PTPRC/B2M/SMARCB1/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4/INPP5D 170
GO:0006968 cellular defense response 65/3662 97/15509 1.231e-19 7.78542e-18 4.68201e-18 TYROBP/GNLY/PTK2B/BECN1/ITGB1/CCR5/CX3CR1/RELA/CCR9/FOSL1/PRF1/CXCR2/KIR2DL4/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DS3/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DS3/KIR2DS3/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DS3/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DS3/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DS3/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DS3 65
GO:0019221 cytokine-mediated signaling pathway 192/3662 451/15509 1.45675e-19 9.12014e-18 5.48469e-18 BAD/ADIPOR2/PAFAH1B1/CD4/CD74/BIRC3/FAS/CD44/TNFRSF1B/TNFRSF17/TRAF1/ZC3H15/SPI1/SP100/PRKACA/IL4R/UBE2K/PTPRC/IL12RB2/MAVS/IL5RA/IL12RB1/OSM/PDGFB/CTSG/NFKBIA/BIRC7/HCK/CCL22/CCL17/PYCARD/IL21R/IL7/LILRB1/IL27RA/JAK3/CXCL12/CSF3/CCL2/HPX/KRT18/SH2B3/IFNG/IL17A/IL12B/IL5/LIFR/WNT5A/IL1A/CCL20/DOK1/STAT1/LEPR/PADI2/MPL/TNFAIP3/ARG1/FOXO3/CSF3R/GPR75/EGR1/PTK2B/CXCR4/FLT3/CNTFR/H2BC11/RNF113A/IL1B/CD70/CCR7/IRF3/STAT5A/IRF5/EPO/PXDN/EDA2R/TRAF3/PIAS3/IL2RA/IL6/TANK/IL1RN/IL11RA/CCL21/BBS4/SMAD4/TNFRSF11A/CNOT9/SLIT2/IL2RG/UGCG/NOTCH1/COMMD7/IL18/CXCL13/KIT/APPL1/ADIPOR1/TNFRSF13C/CXCR5/IL6R/CCR5/JAK1/GFI1/RBM15/CXCR1/PF4/CSF2/SYK/WBP1L/TRIM44/FADD/NKIRAS2/CX3CR1/TNIP2/CXCL8/LIMS1/TRIM56/CCL11/CCL19/RELA/CCR9/STAT5B/LEP/FZD4/PTPN2/PTPN11/CXCR2/ADIPOQ/CSF1R/PLCB1/TRAIP/CCR4/IRAK1/SLIT3/CSF1/CIB1/SIGIRR/IL3RA/SOCS1/PRKN/YTHDF3/IFITM1/CXCR3/LILRB4/EPOR/IL1RAP/SRC/NKIRAS1/IFNA1/CSNK2B/TNF/TMSB4X/CRLF2/TNF/ACKR1/CHUK/CPNE1/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/IL10RB/CEBPA/NAIP/LSM14A/PTPRC/CCL5/CD24/CCL5/LILRB1/CCL4/CCL18/CCL4/LILRB4/NAIP/LILRB1/LILRB1/LILRB1/CCL4/CCL18/CCL18/LILRB4/LILRB4/NAIP/PRKACA 192
GO:2000772 regulation of cellular senescence 63/3662 93/15509 1.89678e-19 1.17562e-17 7.07e-18 SIRT6/ARG2/ZMPSTE24/ABL1/BMPR1A/FBXO5/BCL6/NEK4/EEF1E1/PLK2/HMGA2/TERT/KIR2DL4/ZNF277/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/KIR2DL4/B2M/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/AKT3/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/MIF/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/PTEN 63
GO:0001912 positive regulation of leukocyte mediated cytotoxicity 66/3662 100/15509 2.23016e-19 1.36857e-17 8.23031e-18 TYROBP/SPI1/PTPRC/P2RX7/IL12RB1/IL12B/CD160/ARG1/NECTIN2/IL21/MR1/CD1A/CD1C/CD1B/FADD/ITGAM/STAT5B/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/NCR3/HLA-A/HLA-A/HLA-B/HLA-E/NCR3/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-B/TAP2/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/TAP2/NCR3/PTPRC/B2M/HLA-G/HLA-DRA 66
GO:0045089 positive regulation of innate immune response 99/3662 182/15509 2.33408e-19 1.4183e-17 8.5294e-18 TYROBP/SPI1/UBE2K/XRCC5/MAVS/HCK/RIOK3/TLR8/PYCARD/HPX/IL12B/WNT5A/CD160/IRF3/NECTIN2/TRIM5/POLR3F/AKIRIN2/TLR4/IL21/SLC15A4/NONO/GBP5/SYK/MBL2/NOD2/FADD/POLR3D/TRIM56/STAT5B/PAK2/HEXIM1/CARD9/PLSCR1/KIR2DL4/HMGB1/SRC/HLA-E/HLA-G/HLA-E/HLA-G/NCR3/HLA-E/NCR3/HLA-E/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/PRKDC/LSM14A/CCL5/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/CCL5/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 99
GO:0002711 positive regulation of T cell mediated immunity 63/3662 94/15509 4.43313e-19 2.66763e-17 1.60426e-17 FOXP3/TBX21/PTPRC/P2RX7/IL12RB1/GATA3/CD81/IL12B/IL4/IL1B/NECTIN2/IL6/IL18/MR1/CD1A/CD1C/CD1B/FADD/ZP3/CD55/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-DRA/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/TAP2/HLA-A/HLA-DRA/TAP2/HLA-B/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-B/TAP2/HLA-G/HLA-E/HLA-DRA/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/PTPRC/B2M/HLA-G/HLA-DRA 63
GO:0046634 regulation of alpha-beta T cell activation 79/3662 132/15509 4.62205e-19 2.75456e-17 1.65655e-17 HFE/RUNX3/FOXP3/PRDM1/AP3D1/RHOA/CBFB/TBX21/IL4R/ARG2/PTPRC/IL12RB1/SMAD7/LILRB1/JAK3/GATA3/ZBTB16/CD81/IFNG/IL12B/IL4/BCL6/CD86/ZAP70/CD160/MYB/CD80/TWSG1/NDFIP1/RARA/AP3B1/PTPN22/IL2RA/HLX/IRF4/IL2RG/IL18/RUNX1/TGFBR2/SHH/SYK/LGALS9/CCL19/CD28/KLHL25/SOCS1/LILRB4/HMGB1/CD55/PNP/HLA-E/HLA-DRA/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-DRA/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-DRA/HLA-A/HLA-E/PTPRC/LILRB1/LILRB4/LILRB1/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4/ITCH 79
GO:0032946 positive regulation of mononuclear cell proliferation 90/3662 160/15509 5.262e-19 3.10608e-17 1.86794e-17 CD38/BTK/IGF1/CD74/FOXP3/ST6GAL1/PTPRC/IL12RB1/CD40/NFATC2/CD40LG/PYCARD/IL7/IL27RA/JAK3/CD81/IL12B/IL4/IL5/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/MPL/GPAM/CD80/CDKN1A/IL1B/TNFSF9/CD70/EPO/EPHB2/PTPN22/IL2RA/IL6/TLR4/IL21/SLC7A1/IL18/TNFRSF13C/ICOSLG/VCAM1/TGFBR2/SPTA1/SHH/SYK/FADD/LGALS9/BCL2L1/CCL19/STAT5B/LEP/CD28/CSF1/ZP3/HMGB1/CD55/PDCD1LG2/PNP/HLA-E/HLA-E/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-E/HLA-A/HLA-E/HLA-DPB1/HLA-DPB1/PTPRC/CCL5/CD24/CCL5/MIF 90
GO:0032496 response to lipopolysaccharide 144/3662 310/15509 5.50794e-19 3.22059e-17 1.9368e-17 UPF1/MPO/PAF1/SELE/BTK/LTF/SLC11A1/CPS1/TNFRSF1B/FOXP3/SPI1/FGFR2/RHOA/IL12RB2/OPRK1/APOB/CHMP5/P2RX7/CEBPE/ABL1/XBP1/CTSG/PABPN1/PCK2/NFKBIA/HCK/GATA1/ACP5/PYCARD/LILRB1/TGFB1/HAMP/SERPINE1/MAPK8/CSF3/RPS6KB1/CCL2/CYP27B1/AICDA/PPARD/MAPK14/IL12B/CD86/WNT5A/IL1A/FASLG/TNFAIP3/ARG1/CD80/NR4A1/IL1B/CCR7/NR1D1/IRF3/ZFP36/CD68/EPO/ASS1/AKAP12/RARA/TRIM5/EPHB2/PTPN22/CD36/AKIRIN2/EDNRB/IL6/IL10/TLR4/IL18BP/SMAD6/CYP1A1/IRF8/TNFRSF11A/DUSP10/REN/ALAD/NOTCH1/IL18/BMP6/CD96/PRKCA/CXCL13/ADAMTS13/CCR5/GFI1/VCAM1/MAPKAPK2/IL24/CAPN2/PF4/CASP3/CSF2/NOS3/NOD2/PRDX2/CX3CR1/ADAM9/TNIP2/LGALS9/PTAFR/CXCL8/FOS/CD14/PRKCE/CEBPB/RELA/CNP/SELP/F2R/IRAK1/CSF1/PDE4B/SIGIRR/CNR2/HMGB1/CD55/SRC/SHPK/ELANE/PDCD1LG2/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/CCL5/CCL5/PRPF8/LILRB1/LILRB1/MIF/LILRB1/ELANE/LILRB1/ADAMTS13 144
GO:0045580 regulation of T cell differentiation 93/3662 168/15509 5.92645e-19 3.43291e-17 2.06449e-17 BAD/CD74/RUNX3/ARID1B/FOXP3/PRDM1/AP3D1/RHOA/CBFB/TBX21/GLI2/ACTB/IL4R/PTPRC/IL12RB1/ABL1/SMARCB1/XBP1/SMAD7/IL7/JAK3/GATA3/ZMIZ1/SMARCD2/ZBTB16/MDK/IFNG/IL12B/IL4/BCL6/CD86/ZAP70/ARID1A/MYB/FOXO3/CD80/SOX4/TNFSF9/FOXJ1/RARA/AP3B1/IL2RA/HLX/IRF4/SOD1/DUSP10/IL2RG/ZEB1/IL18/RUNX1/TGFBR2/CTLA4/SHH/SYK/BRD7/RAG1/PRDX2/RHOH/LGALS9/PRELID1/CCL19/KAT5/STAT5B/RAG2/PTPN2/CD28/KLHL25/SOCS1/LILRB4/ARID2/HMGB1/NRARP/PNP/CR1/HLA-DOA/HLA-G/HLA-DRA/HLA-G/HLA-DRA/HLA-DRA/HLA-G/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/PTPRC/SMARCB1/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4 93
GO:0071216 cellular response to biotic stimulus 117/3662 233/15509 6.28229e-19 3.60534e-17 2.16819e-17 UPF1/PAF1/BTK/LTF/TNFRSF1B/HSPA5/SPI1/RHOA/SIRT2/SMC1A/FCGR2B/OPRK1/GSK3B/ZMPSTE24/CHMP5/CEBPE/ABL1/XBP1/CTSG/PABPN1/NFKBIA/HCK/GATA1/PYCARD/LILRB1/TGFB1/HAMP/SERPINE1/MAPK8/CSF3/CCDC47/CCL2/AICDA/PPARD/MAPK14/IL12B/CD86/WNT5A/IL1A/TNFAIP3/ARG1/CD80/IL1B/NR1D1/IRF3/ZFP36/CD68/ASS1/RARA/TRIM5/EPHB2/PTPN22/NOTCH2/CD36/EDNRB/IL6/IL10/TLR4/IGFBPL1/IRF8/TMCO1/NOTCH1/IL18/BCL2L11/BMP6/PRKCA/EME1/CXCL13/PPP1R15B/ADAMTS13/CCR5/GFI1/IL24/CAPN2/PF4/CSF2/NOS3/SYK/NOD2/PRDX2/CX3CR1/ADAM9/TNIP2/PTAFR/CXCL8/CD14/PRKCE/EIF2AK3/CEBPB/RELA/DDIT3/IRAK1/PDE4B/SIGIRR/HMGB1/CD55/SRC/SHPK/PDCD1LG2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TXNIP/CCL5/CCL5/PRPF8/LILRB1/LILRB1/MIF/LILRB1/LILRB1/ADAMTS13 117
GO:0070665 positive regulation of leukocyte proliferation 96/3662 176/15509 6.35732e-19 3.61492e-17 2.17395e-17 CD38/BTK/IGF1/CD74/FOXP3/ST6GAL1/PTPRC/IL5RA/IL12RB1/CD40/NFATC2/CD40LG/PYCARD/IL7/IL27RA/JAK3/CD81/IL12B/IL4/IL5/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/MPL/GPAM/CD80/CDKN1A/IL1B/TNFSF9/CD70/RAC2/EPO/EPHB2/PTPN22/IL2RA/IL6/TLR4/IL21/SLC7A1/IL18/KIT/TNFRSF13C/ICOSLG/VCAM1/TGFBR2/SPTA1/CSF2/SHH/SYK/FADD/LGALS9/PTK2/BCL2L1/CCL19/STAT5B/LEP/CD28/CSF1R/CSF1/ZP3/HMGB1/CD55/PDCD1LG2/PNP/HLA-E/HLA-E/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-E/HLA-A/HLA-E/HLA-DPB1/HLA-DPB1/PTPRC/CCL5/CD24/CCL5/MIF 96
GO:0042102 positive regulation of T cell proliferation 74/3662 121/15509 1.05372e-18 5.93722e-17 3.57054e-17 IGF1/FOXP3/PTPRC/IL12RB1/CD40LG/PYCARD/IL27RA/JAK3/CD81/IL12B/IL4/CD86/HES1/IL1A/ZAP70/IGFBP2/GPAM/CD80/IL1B/TNFSF9/CD70/EPO/PTPN22/IL2RA/IL6/IL21/SLC7A1/IL18/TNFRSF13C/ICOSLG/VCAM1/TGFBR2/SPTA1/SHH/SYK/FADD/LGALS9/CCL19/STAT5B/LEP/CD28/ZP3/HMGB1/CD55/PDCD1LG2/PNP/HLA-E/HLA-E/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-E/HLA-A/HLA-E/HLA-DPB1/HLA-DPB1/PTPRC/CCL5/CD24/CCL5 74
GO:0002377 immunoglobulin production 94/3662 173/15509 2.08982e-18 1.16691e-16 7.01758e-17 BTK/CD22/PARP3/FOXP3/TCF3/FCGR2B/TBX21/MLH1/IL4R/PTPRC/MSH2/XBP1/CD40/CD40LG/NBN/IL27RA/GPI/TGFB1/EXOSC3/NSD2/HPX/AICDA/IL4/IL5/BCL6/CD86/SHLD2/PKN1/NDFIP1/EPHB2/IL6/IL10/IL21/SLC15A4/TMBIM6/TNFSF13/LIG4/CD28/HLA-DQB1/HLA-DQA1/CR1/HLA-DOA/TNF/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/TNF/HLA-E/HLA-DPB1/HLA-DQA1/HLA-DPB1/TNF/HLA-DQA1/HLA-E/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-DRA/HLA-DQA1/TNF/TNF/TNF/HLA-DRA/HLA-E/HLA-DPB1/TNF/HLA-E/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-DQB1/HLA-DQA1/TNF/HLA-DQA1/HLA-DQB1/HLA-E/HLA-DRA/HLA-DQA1/HLA-E/HLA-DPB1/HLA-DQA1/HLA-DPB1/PRKDC/HLA-DQA1/PTPRC/B2M/HLA-DRA/GPI 94
GO:0032609 interferon-gamma production 81/3662 141/15509 5.41543e-18 2.97034e-16 1.78631e-16 SLC11A1/BTN3A1/FOXP3/IL12RB2/IL12RB1/ABL1/TLR8/PYCARD/LILRB1/IL27RA/GATA3/C1QBP/IL12B/PDE4D/WNT5A/CD160/CD244/INHBA/IL1B/CCR7/RARA/PTPN22/IL10/TLR4/IL21/IRF8/IL18/CD96/TLR3/NOD2/FADD/LGALS9/CD14/HRAS/DDIT3/PDE4B/BTN3A2/LILRB4/ZP3/HMGB1/TLR7/CD47/PDCD1LG2/CR1/TNF/TNF/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/LTA/TNF/HLA-A/HLA-A/LTA/HLA-DPB1/HLA-A/TNF/TNF/TNF/HLA-A/HLA-DPB1/TNF/LTA/HLA-DPB1/HLA-DPB1/HLA-DPA1/LTA/HLA-A/TNF/HLA-A/HLA-DPB1/HLA-DPB1/LTA/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 81
GO:0032649 regulation of interferon-gamma production 81/3662 141/15509 5.41543e-18 2.97034e-16 1.78631e-16 SLC11A1/BTN3A1/FOXP3/IL12RB2/IL12RB1/ABL1/TLR8/PYCARD/LILRB1/IL27RA/GATA3/C1QBP/IL12B/PDE4D/WNT5A/CD160/CD244/INHBA/IL1B/CCR7/RARA/PTPN22/IL10/TLR4/IL21/IRF8/IL18/CD96/TLR3/NOD2/FADD/LGALS9/CD14/HRAS/DDIT3/PDE4B/BTN3A2/LILRB4/ZP3/HMGB1/TLR7/CD47/PDCD1LG2/CR1/TNF/TNF/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/LTA/TNF/HLA-A/HLA-A/LTA/HLA-DPB1/HLA-A/TNF/TNF/TNF/HLA-A/HLA-DPB1/TNF/LTA/HLA-DPB1/HLA-DPB1/HLA-DPA1/LTA/HLA-A/TNF/HLA-A/HLA-DPB1/HLA-DPB1/LTA/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 81
GO:0050671 positive regulation of lymphocyte proliferation 87/3662 157/15509 7.38883e-18 4.01719e-16 2.41587e-16 CD38/BTK/IGF1/CD74/FOXP3/PTPRC/IL12RB1/CD40/NFATC2/CD40LG/PYCARD/IL7/IL27RA/JAK3/CD81/IL12B/IL4/IL5/BCL6/CD86/HES1/IL1A/ZAP70/IGFBP2/MPL/GPAM/CD80/CDKN1A/IL1B/TNFSF9/CD70/EPO/EPHB2/PTPN22/IL2RA/IL6/TLR4/IL21/SLC7A1/IL18/TNFRSF13C/ICOSLG/VCAM1/TGFBR2/SPTA1/SHH/SYK/FADD/LGALS9/CCL19/STAT5B/LEP/CD28/ZP3/HMGB1/CD55/PDCD1LG2/PNP/HLA-E/HLA-E/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-A/HLA-A/HLA-E/HLA-DPB1/HLA-E/HLA-DPB1/HLA-DPB1/HLA-DPA1/HLA-A/HLA-E/HLA-A/HLA-E/HLA-DPB1/HLA-DPB1/PTPRC/CCL5/CD24/CCL5/MIF 87
GO:0046635 positive regulation of alpha-beta T cell activation 59/3662 89/15509 1.31443e-17 7.08423e-16 4.26033e-16 RUNX3/FOXP3/AP3D1/RHOA/CBFB/IL4R/PTPRC/IL12RB1/ZBTB16/CD81/IFNG/IL12B/CD86/ZAP70/CD160/MYB/CD80/RARA/AP3B1/PTPN22/HLX/IL2RG/IL18/RUNX1/TGFBR2/SHH/SYK/LGALS9/CCL19/CD28/KLHL25/SOCS1/LILRB4/CD55/PNP/HLA-E/HLA-DRA/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-DRA/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-DRA/HLA-A/HLA-E/PTPRC/LILRB4/HLA-DRA/LILRB4/LILRB4 59
GO:0042270 protection from natural killer cell mediated cytotoxicity 29/3662 30/15509 1.41052e-17 7.53654e-16 4.53234e-16 SERPINB9/HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-B/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/HLA-G 29
GO:0032729 positive regulation of interferon-gamma production 63/3662 99/15509 2.28839e-17 1.21226e-15 7.29032e-16 SLC11A1/BTN3A1/IL12RB2/IL12RB1/ABL1/TLR8/PYCARD/LILRB1/IL27RA/IL12B/PDE4D/WNT5A/CD160/CD244/IL1B/PTPN22/TLR4/IL21/IRF8/IL18/TLR3/FADD/LGALS9/CD14/HRAS/PDE4B/BTN3A2/ZP3/TLR7/TNF/TNF/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/LTA/TNF/HLA-A/HLA-A/LTA/HLA-DPB1/HLA-A/TNF/TNF/TNF/HLA-A/HLA-DPB1/TNF/LTA/HLA-DPB1/HLA-DPB1/HLA-DPA1/LTA/HLA-A/TNF/HLA-A/HLA-DPB1/HLA-DPB1/LTA/LILRB1/LILRB1/LILRB1/LILRB1 63
GO:0002833 positive regulation of response to biotic stimulus 110/3662 222/15509 2.49369e-17 1.30982e-15 7.87705e-16 TYROBP/GRN/CYBA/PUM2/SPI1/UBE2K/XRCC5/MAVS/HCK/RIOK3/TLR8/PYCARD/HPX/IL17A/IL12B/WNT5A/CD160/ARG1/IRF3/NECTIN2/TRIM5/POLR3F/AKIRIN2/TLR4/DDX60/IL21/SLC15A4/NONO/MR1/BMP6/PRKCA/GBP5/SYK/MBL2/NOD2/FADD/POLR3D/TRIM56/CD14/STAT5B/PAK2/HEXIM1/CARD9/PLSCR1/KIR2DL4/HMGB1/SRC/HLA-E/HLA-G/HLA-E/HLA-G/NCR3/HLA-E/NCR3/HLA-E/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/HLA-G/NCR3/HLA-E/NCR3/NCR3/HLA-G/NCR3/PRKDC/LSM14A/CCL5/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/CCL5/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/HLA-G/MIF/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4/KIR2DL4 110
GO:0043410 positive regulation of MAPK cascade 187/3662 459/15509 1.07183e-16 5.58253e-15 3.35724e-15 WNT16/DHX33/NOX1/SPAG9/MAPK8IP2/CD4/IGF1/CD74/HGF/CD44/CASR/FLT4/EIF2AK2/TRAF1/HIPK2/MAP2K4/SPI1/FGFR2/ROCK1/FGFR3/NDST1/CDC42/EPHA8/FCGR2B/TRAF4/FGFR1/TP73/PTPRC/OPRK1/NOX4/P2RX7/ICAM1/ABL1/GADD45B/OSM/PDGFB/CD40/BIRC7/RASSF2/FLT1/CCL22/CCL17/NDRG4/AXIN1/PYCARD/CSK/PRKD2/TGFB1/PIK3CG/GSDME/NOD1/EZH2/TGFBR1/ACTA2/DKK1/CCL2/MAP2K6/LAMTOR3/CD81/FZD10/PDGFRB/WNT5A/IL1A/CCL20/GADD45A/NENF/TEK/PTK2B/IAPP/FLT3/INHBA/IL1B/BMP2/CCR7/PRMT1/KDR/LIF/AJUBA/SHC2/APOE/EPO/GDF15/AKAP12/EDA2R/TRAF3/TRIM5/CHI3L1/PTPN22/NOTCH2/PDGFRA/CD36/SPRY2/IL6/TLR4/CCL21/THBS1/PLCE1/FGF2/EGF/MAP3K12/IGF1R/ARRB2/TNFRSF11A/SOD1/APP/ARL6IP5/PDGFC/TPBG/EGFR/IGFBP3/NTRK2/NOTCH1/MBIP/PRKCA/NODAL/KIT/SHC1/DVL3/ALOX15/TLR3/GPER1/SYK/FRS2/NOD2/PRDX2/ADAM9/SEMA4C/LGALS9/EFNA1/ADRB2/CDH2/ALK/PRKCE/LPAR3/FGG/FGA/CCL11/CCL19/CSPG4/LEP/HRAS/FZD4/JUN/ERN1/PTPN11/F2R/CSF1R/PLCB1/ADRA2C/IRAK1/CIB1/CDK10/CARD9/WNT7B/HMGB1/PPIA/SRC/MAP3K5/ELANE/NTRK1/TNF/DOK6/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/ITGB3/GH1/PTPRC/CCL5/CD24/CCL5/CCL4/CCL18/CCL4/NAIP/MIF/ELANE/CCL4/CCL18/CCL18/NAIP/PTEN 187
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 48/3662 67/15509 1.1129e-16 5.74814e-15 3.45683e-15 HFE/MR1/ERAP2/TAP1/CALR/TAP2/HLA-E/HLA-G/TAP2/TAP1/TAP2/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/TAP2/HLA-B/HLA-A/TAP1/HLA-A/HLA-B/HLA-E/TAP2/TAP1/HLA-A/TAP1/TAP2/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/TAP1/HLA-A/TAPBP/HLA-B/TAP2/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/TAP2/B2M/HLA-G 48
GO:0030217 T cell differentiation 127/3662 277/15509 2.43878e-16 1.24922e-14 7.51259e-15 BAD/TMEM98/CD4/CD74/RUNX3/ARID1B/FOXP3/PRDM1/AP3D1/SPI1/RHOA/CBFB/TBX21/GLI2/ACTB/IL4R/PTPRC/IL12RB1/ABL1/SMARCB1/XBP1/SMAD7/IL7/KDELR1/JAK3/TNFSF8/GATA3/PPP3CB/ZMIZ1/SMARCD2/ZBTB16/MDK/IFNG/IL12B/IL4/BCL6/CD86/IL1A/ZAP70/LEPR/ARID1A/MYB/FOXO3/EGR1/CD80/SOX4/RUNX2/IL1B/TNFSF9/CCR7/BCL11B/FOXJ1/RARA/AP3B1/PTPN22/IL2RA/IL6/HLX/IRF4/IL21/ARMC5/SOD1/DUSP10/PIK3R1/IL2RG/ZEB1/IL18/ZFP36L2/MR1/CD8A/KIT/RUNX1/IL6R/WNT4/TGFBR2/CTLA4/SHH/SYK/BRD7/RAG1/PRDX2/FADD/RHOH/LGALS9/PRELID1/CCL19/KAT5/CCR9/STAT5B/LIG4/LEP/RAG2/PTPN2/CD28/KLHL25/SOCS1/ZFP36L1/LILRB4/ARID2/HMGB1/ENTPD7/NRARP/MTOR/PNP/CR1/MAFB/HLA-DOA/HLA-G/HLA-DRA/HLA-G/HLA-DRA/HLA-DRA/HLA-G/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/PRKDC/PTPRC/B2M/SMARCB1/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4 127
GO:0033674 positive regulation of kinase activity 187/3662 463/15509 3.03026e-16 1.53947e-14 9.25811e-15 BAD/DBF4/CD4/LTF/IGF1/SLC11A1/CD74/FLT4/EPHA3/ATP2B4/ERBB3/TIE1/FGFR2/RHOA/FGFR3/CDC42/EPHA8/MARK2/TRAF4/FGFR1/XRCC5/EPHA6/PTPRC/DUSP12/DLG3/PIBF1/NOX4/TPX2/P2RX7/GCN1/CCNK/CDC6/HSP90AB1/ABL1/PDGFB/TCL1A/CD40/ADNP/EEF1A2/CDC25B/RASSF2/CD40LG/FLT1/AXIN1/CSK/NBN/TGFB1/PIK3CG/MET/EZH2/BMPR1A/DKK1/MAP2K6/UNC119/LAMTOR3/AREG/CCND1/CD81/CALCA/FZD10/IFNG/NEDD9/CCND3/HBEGF/IL12B/IL4/RAD50/PPP2CA/PDGFRB/CD86/WNT5A/MOB1A/PARK7/PKD2/TEK/EGR1/CLU/TNFRSF10B/PTK2B/FLT3/CDKN1A/IL1B/BMP2/CCR7/ATG14/KDR/AJUBA/EPO/CHI3L1/EPHB2/CCNB1/PSRC1/PDGFRA/BORA/SPRY2/TLR4/CCL21/THBS1/FGF2/CENPE/EGF/MAP3K12/IGF1R/TNFRSF11A/EPHA2/CCN1/CALM2/EPHA5/PDGFC/EGFR/VLDLR/NTRK2/HMGA2/VEGFC/IL18/CACUL1/RANBP2/MERTK/KIT/CALM3/IL6R/MRNIP/DVL3/DBF4B/TGFBR2/PRKCD/RICTOR/TLR3/CDK5/SYK/NOD2/ADAM9/EFNA1/ADRB2/PTK2/GPRC5C/ALK/MOB3A/CCL19/CKS1B/DAG1/LEP/HRAS/FZD4/CDK5R1/CD19/ERN1/F2/PAK2/ADIPOQ/NPM1/CSF1R/EPHB3/ADRA2C/IRAK1/CSF1/CIB1/SOCS1/ROR1/PPIA/SRC/MAP3K5/ELANE/NTRK1/MTOR/TNF/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF/ITGB3/GH1/PTPRC/CCL5/CD24/CCL5/EPHB6/MIF/ELANE 187
GO:0002381 immunoglobulin production involved in immunoglobulin-mediated immune response 62/3662 101/15509 5.22433e-16 2.63255e-14 1.58317e-14 BTK/PARP3/FOXP3/TBX21/MLH1/PTPRC/MSH2/CD40/CD40LG/NBN/IL27RA/TGFB1/EXOSC3/NSD2/AICDA/IL4/BCL6/SHLD2/NDFIP1/IL10/SLC15A4/TNFSF13/LIG4/CD28/HLA-DQB1/HLA-DQA1/HLA-DOA/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DQA1/HLA-DQB1/HLA-DRA/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/PTPRC/B2M/HLA-DRA 62
GO:0002486 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent 28/3662 30/15509 6.74063e-16 3.36923e-14 2.0262e-14 HLA-E/HLA-G/HLA-B/HLA-E/HLA-A/HLA-A/HLA-G/HLA-B/HLA-A/HLA-A/HLA-B/HLA-E/HLA-A/HLA-B/HLA-A/HLA-E/HLA-E/HLA-G/HLA-A/HLA-B/HLA-G/HLA-E/HLA-G/HLA-A/HLA-G/HLA-E/HLA-G/HLA-G 28
GO:0032615 interleukin-12 production 51/3662 76/15509 9.65769e-16 4.75066e-14 2.85697e-14 PIBF1/MAST2/CD40/TLR8/CD40LG/ACP5/MEFV/LILRB1/JAK3/C1QBP/MDK/IFNG/MAPK14/IL17A/IL12B/CCR7/IRF5/CD36/IL10/TLR4/THBS1/IRF8/ARRB2/TLR3/SYK/NOD2/LGALS9/IL16/CCL19/RELA/LEP/PLCB1/HMGB1/CD47/HLA-G/HLA-B/HLA-G/HLA-B/HLA-B/HLA-B/HLA-G/HLA-B/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1 51
GO:0032655 regulation of interleukin-12 production 51/3662 76/15509 9.65769e-16 4.75066e-14 2.85697e-14 PIBF1/MAST2/CD40/TLR8/CD40LG/ACP5/MEFV/LILRB1/JAK3/C1QBP/MDK/IFNG/MAPK14/IL17A/IL12B/CCR7/IRF5/CD36/IL10/TLR4/THBS1/IRF8/ARRB2/TLR3/SYK/NOD2/LGALS9/IL16/CCL19/RELA/LEP/PLCB1/HMGB1/CD47/HLA-G/HLA-B/HLA-G/HLA-B/HLA-B/HLA-B/HLA-G/HLA-B/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1 51
GO:1903707 negative regulation of hemopoiesis 64/3662 107/15509 1.08915e-15 5.3154e-14 3.19659e-14 LTF/SNAI2/CD74/RUNX3/HMGB3/FOXP3/CBFB/FCGR2B/TBX21/IL4R/SMAD7/SFRP1/LILRB1/JAK3/MDK/HSPA9/IL4/BCL6/ID2/IAPP/INHBA/LRRC17/FOXJ1/RARA/PIAS3/HLX/TLR4/CUL4A/TCTA/PIK3R1/RUNX1/CTLA4/TLR3/SHH/TNFRSF11B/PRDX2/INPP5D/GPR137/RAG2/PTPN2/ADIPOQ/SOCS1/LILRB4/HMGB1/NRARP/CR1/MAFB/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/CEBPA/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D 64
GO:0002761 regulation of myeloid leukocyte differentiation 69/3662 121/15509 2.61319e-15 1.26536e-13 7.60962e-14 CD4/TYROBP/LTF/CD74/TFE3/ACIN1/RASSF2/SFRP1/LILRB1/TGFB1/IFNG/NEDD9/IL17A/IL12B/IL4/IL5/ID2/IAPP/INHBA/LIF/LRRC17/NDFIP1/RARA/PIAS3/NOTCH2/TLR4/RB1/CUL4A/TCTA/PIK3R1/POU4F2/POU4F1/PRKCA/KLF10/RUNX1/PF4/SLC9B2/TLR3/TNFRSF11B/FADD/INPP5D/FOS/CEBPB/ESRRA/GPR137/PTPN2/CTNNBIP1/ADIPOQ/CSF1/ZFP36L1/LILRB4/MTOR/MAFB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D 69
GO:0030316 osteoclast differentiation 63/3662 106/15509 2.79904e-15 1.34484e-13 8.08763e-14 PAFAH1B1/TYROBP/LTF/GAB2/TFE3/ATP6AP1/OSTM1/RASSF2/SFRP1/LILRB1/SH3PXD2A/CD81/IFNG/NEDD9/MAPK14/IL17A/IL12B/IL4/IAPP/LRRC17/PIAS3/NOTCH2/IREB2/TLR4/TNFRSF11A/EPHA2/TCTA/PIK3R1/POU4F2/POU4F1/KLF10/SLC9B2/TLR3/TNFRSF11B/INPP5D/FOS/CEBPB/ESRRA/GPR137/FAM20C/CSF1R/ANXA2/CSF1/LILRB4/SRC/MTOR/MAFB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D 63
GO:0071222 cellular response to lipopolysaccharide 98/3662 200/15509 3.45055e-15 1.64512e-13 9.89345e-14 UPF1/PAF1/LTF/TNFRSF1B/SPI1/RHOA/OPRK1/CHMP5/CEBPE/ABL1/XBP1/CTSG/PABPN1/NFKBIA/HCK/GATA1/PYCARD/LILRB1/TGFB1/HAMP/SERPINE1/MAPK8/CSF3/CCL2/AICDA/PPARD/MAPK14/IL12B/CD86/WNT5A/IL1A/TNFAIP3/ARG1/CD80/IL1B/NR1D1/IRF3/ZFP36/CD68/ASS1/RARA/TRIM5/EPHB2/PTPN22/CD36/EDNRB/IL6/IL10/TLR4/IRF8/IL18/BMP6/PRKCA/CXCL13/ADAMTS13/CCR5/GFI1/IL24/CAPN2/PF4/CSF2/NOS3/NOD2/PRDX2/CX3CR1/ADAM9/TNIP2/PTAFR/CXCL8/CD14/PRKCE/CEBPB/RELA/IRAK1/PDE4B/SIGIRR/HMGB1/CD55/SRC/SHPK/PDCD1LG2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CCL5/CCL5/PRPF8/LILRB1/LILRB1/MIF/LILRB1/LILRB1/ADAMTS13 98
GO:0071219 cellular response to molecule of bacterial origin 100/3662 206/15509 3.93079e-15 1.84802e-13 1.11137e-13 UPF1/PAF1/LTF/TNFRSF1B/SPI1/RHOA/SIRT2/FCGR2B/OPRK1/CHMP5/CEBPE/ABL1/XBP1/CTSG/PABPN1/NFKBIA/HCK/GATA1/PYCARD/LILRB1/TGFB1/HAMP/SERPINE1/MAPK8/CSF3/CCL2/AICDA/PPARD/MAPK14/IL12B/CD86/WNT5A/IL1A/TNFAIP3/ARG1/CD80/IL1B/NR1D1/IRF3/ZFP36/CD68/ASS1/RARA/TRIM5/EPHB2/PTPN22/CD36/EDNRB/IL6/IL10/TLR4/IRF8/IL18/BMP6/PRKCA/CXCL13/ADAMTS13/CCR5/GFI1/IL24/CAPN2/PF4/CSF2/NOS3/NOD2/PRDX2/CX3CR1/ADAM9/TNIP2/PTAFR/CXCL8/CD14/PRKCE/CEBPB/RELA/IRAK1/PDE4B/SIGIRR/HMGB1/CD55/SRC/SHPK/PDCD1LG2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CCL5/CCL5/PRPF8/LILRB1/LILRB1/MIF/LILRB1/LILRB1/ADAMTS13 100
GO:0018212 peptidyl-tyrosine modification 153/3662 365/15509 3.93577e-15 1.84802e-13 1.11137e-13 BAZ1B/DYRK4/CD4/BTK/MVP/CLK1/IGF1/CNTN1/CD74/HGF/CD44/FLT4/EPHA3/EIF2AK2/HIPK2/ERBB3/MAP2K4/TIE1/FGFR2/PKM/HYAL2/FGFR3/EPHA8/FGFR1/EPHA6/PTPRC/IL12RB2/DLG3/PIBF1/NOX4/ABL1/OSM/PDGFB/CD40/ADNP/HCK/GATA1/FLT1/CSK/EHD4/SFRP1/IL7/TGFB1/JAK3/MET/CSF3/MAP2K6/UNC119/AREG/HPX/CD81/SH2B3/IFNG/NEDD9/HBEGF/IL12B/IL4/IL5/PPP2CA/PDGFRB/HES1/NCL/ZAP70/PDCL3/STK16/TEK/PTK2B/CD80/FLT3/DYRK2/KDR/LIF/EPO/VPS25/EPHB2/LRP4/PDGFRA/CD36/IL6/ABI2/IL21/EGF/IGF1R/ARRB2/SCYL1/APP/EPHA2/ABL2/DYRK3/EPHA5/PDGFC/EGFR/NCAPG2/NTRK2/IL18/BMP6/MERTK/KIT/DMTN/ITGB2/SHC1/IL6R/JAK1/IL24/PRKCD/RICTOR/IL3/CSF2/SYK/WEE1/ZNF592/NOD2/EFNA1/PTK2/TPST1/ALK/PRKCE/CSPG4/LEP/PTPN2/CHMP6/PTPN11/PAK2/ADIPOQ/CSF1R/EPHB3/SOCS1/ROR1/NF2/LILRB4/SRC/NTRK1/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/GH1/PECAM1/PTPRC/CCL5/CD24/CCL5/EPHB6/LILRB4/MIF/LILRB4/LILRB4 153
GO:0031400 negative regulation of protein modification process 181/3662 454/15509 4.03882e-15 1.88215e-13 1.13189e-13 KDM1A/SPAG9/AASS/CRY1/MVP/UFL1/HGF/BAK1/FOXP3/ATP2B4/IPO5/KDM4A/SPI1/ROCK1/HYAL2/SIRT2/FBLN1/PTPRC/GSK3B/PIBF1/TMED2/PPP1R15A/BAX/RTRAF/DNMT3B/FKBP1A/ABL1/GADD45B/SMARCB1/GSKIP/BMP7/RASSF2/PPP1R16B/SMAD7/N4BP1/PARD6A/TSC2/PYCARD/SFRP1/TGFB1/HSPB1/ENG/DVL1/DKK1/CHORDC1/CORO1C/SH2B3/IFNG/FBXO5/ZNF451/PDE4D/PPP2CA/MACROH2A1/KAT2B/PRKAR2A/KDM3A/PARK7/GADD45A/P3H1/CDC20/TNFAIP3/PTPA/MASTL/TARDBP/CRY2/PKN1/LRP1/CDKN1A/SOX4/IL1B/BMP2/ATG14/STYXL1/CDKN1C/APOE/CEP85/DNMT1/VPS25/PIAS3/PER2/PRKAA1/EPHB2/MEN1/PTPN22/APC/MICAL1/NIBAN1/SPRY2/SORL1/SMAD6/TARBP2/RB1/WARS1/ARRB2/ENSA/DUSP10/CALM2/SPOPL/CTDSP1/SLIT2/BOD1/IGFBP3/NCAPG2/OGT/C9orf72/PARD3/HHEX/CNKSR3/UCHL1/GNAQ/SKI/PPP1R15B/DMTN/CTBP1/CALM3/TBC1D24/CAMK2N1/PRKCD/DUSP7/CASP3/CDK5/TRIM44/NXN/DDIT4/PKIG/RGS14/PRKCE/RELA/GLMN/CTDSP2/BANF1/PTPN2/CHMP6/JUN/SVBP/PLEC/TAF7/PAK2/ADIPOQ/NPM1/ADGRB1/SLC8A1/NOG/CIB1/INPP5J/SOCS1/PRKN/NF2/LILRB4/HEXIM1/SPRY4/NOC2L/PAX5/PPIA/WDR5/SPRED2/TNF/PPP1R11/AKT1S1/IPO7/TNF/TNF/TNF/TNF/TNF/TNF/TNF/DBNDD2/CEBPA/PRKDC/PTPRC/CDKN1C/SMARCB1/LILRB4/LILRB4/LILRB4/LRP6/SQSTM1/PTEN/TINF2/CHORDC1 181
GO:1902106 negative regulation of leukocyte differentiation 61/3662 102/15509 5.14262e-15 2.37865e-13 1.43048e-13 LTF/CD74/RUNX3/HMGB3/FOXP3/CBFB/FCGR2B/TBX21/IL4R/SMAD7/SFRP1/LILRB1/JAK3/MDK/IL4/BCL6/ID2/IAPP/INHBA/LRRC17/FOXJ1/RARA/PIAS3/HLX/TLR4/CUL4A/TCTA/PIK3R1/RUNX1/CTLA4/TLR3/SHH/TNFRSF11B/PRDX2/INPP5D/GPR137/RAG2/PTPN2/ADIPOQ/SOCS1/LILRB4/HMGB1/NRARP/CR1/MAFB/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D 61
GO:0018108 peptidyl-tyrosine phosphorylation 152/3662 363/15509 5.40384e-15 2.48096e-13 1.49201e-13 BAZ1B/DYRK4/CD4/BTK/MVP/CLK1/IGF1/CNTN1/CD74/HGF/CD44/FLT4/EPHA3/EIF2AK2/HIPK2/ERBB3/MAP2K4/TIE1/FGFR2/PKM/HYAL2/FGFR3/EPHA8/FGFR1/EPHA6/PTPRC/IL12RB2/DLG3/PIBF1/NOX4/ABL1/OSM/PDGFB/CD40/ADNP/HCK/GATA1/FLT1/CSK/EHD4/SFRP1/IL7/TGFB1/JAK3/MET/CSF3/MAP2K6/UNC119/AREG/HPX/CD81/SH2B3/IFNG/NEDD9/HBEGF/IL12B/IL4/IL5/PPP2CA/PDGFRB/HES1/NCL/ZAP70/PDCL3/STK16/TEK/PTK2B/CD80/FLT3/DYRK2/KDR/LIF/EPO/VPS25/EPHB2/LRP4/PDGFRA/CD36/IL6/ABI2/IL21/EGF/IGF1R/ARRB2/SCYL1/APP/EPHA2/ABL2/DYRK3/EPHA5/PDGFC/EGFR/NCAPG2/NTRK2/IL18/BMP6/MERTK/KIT/DMTN/ITGB2/SHC1/IL6R/JAK1/IL24/PRKCD/RICTOR/IL3/CSF2/SYK/WEE1/ZNF592/NOD2/EFNA1/PTK2/ALK/PRKCE/CSPG4/LEP/PTPN2/CHMP6/PTPN11/PAK2/ADIPOQ/CSF1R/EPHB3/SOCS1/ROR1/NF2/LILRB4/SRC/NTRK1/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/GH1/PECAM1/PTPRC/CCL5/CD24/CCL5/EPHB6/LILRB4/MIF/LILRB4/LILRB4 152
GO:0002396 MHC protein complex assembly 39/3662 52/15509 6.69071e-15 3.02693e-13 1.82035e-13 CALR/HLA-DQB1/HLA-DQA1/HLA-DOA/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/TAPBP/HLA-DQB1/HLA-DQA1/HLA-DQA1/HLA-DQB1/HLA-DRA/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/B2M/HLA-DRA 39
GO:0002501 peptide antigen assembly with MHC protein complex 39/3662 52/15509 6.69071e-15 3.02693e-13 1.82035e-13 CALR/HLA-DQB1/HLA-DQA1/HLA-DOA/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/TAPBP/HLA-DQB1/HLA-DQA1/HLA-DQA1/HLA-DQB1/HLA-DRA/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/B2M/HLA-DRA 39
GO:0048872 homeostasis of number of cells 122/3662 272/15509 7.16518e-15 3.2181e-13 1.93531e-13 SLC4A1/KMT2E/BTK/UFL1/CD74/ALAS1/FAS/BAK1/TNFRSF17/FOXP3/KCNQ1/HIPK2/SPI1/BAX/P2RX7/ABL1/MTHFD1/ACIN1/RASSF2/GATA1/IL7/ERCC2/GPI/KLF1/JAK3/HAMP/HOXA5/ZNHIT1/EZH2/GATA3/PPP3CB/SEPTIN4/HOXB6/SLC11A2/SH2B3/MAPK14/RHAG/HSPA9/SMAD5/BCL6/STAT1/ID2/EPAS1/MPL/PRDX1/TNFAIP3/MYB/FOXO3/PTBP3/GPAM/FLT3/INHBA/PKN1/SOX4/THRA/CCR7/PRMT1/ZFP36/EPO/AP3B1/KRAS/IL2RA/ABCB10/IL6/IREB2/CCN3/SLC15A4/RB1/PMAIP1/SOD1/ARNT/DYRK3/UBAP2L/NCAPG2/NOTCH1/BCL2L11/MERTK/KIT/TSC22D3/XKR8/FANCC/ALAS2/DMTN/TAL1/SPTA1/BAP1/CASP3/SFXN1/NOS3/RAG1/LMO1/EPB42/PRDX2/FADD/CX3CR1/INPP5D/LGALS9/AHSP/CDH2/STAT5B/PTPN2/PTPN11/CXCR2/F2R/RPS17/CCR4/CSF1/PDE4B/ZFP36L1/CDIN1/CARD9/HMGB1/L3MBTL3/MAFB/GIGYF2/TNFRSF13B/PRKDC/B2M/AKT3/MIF/INPP5D/GPI 122
GO:0002399 MHC class II protein complex assembly 37/3662 48/15509 7.30258e-15 3.23296e-13 1.94424e-13 HLA-DQB1/HLA-DQA1/HLA-DOA/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DQA1/HLA-DQB1/HLA-DRA/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/B2M/HLA-DRA 37
GO:0002503 peptide antigen assembly with MHC class II protein complex 37/3662 48/15509 7.30258e-15 3.23296e-13 1.94424e-13 HLA-DQB1/HLA-DQA1/HLA-DOA/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DQA1/HLA-DQB1/HLA-DRA/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/B2M/HLA-DRA 37
GO:0048659 smooth muscle cell proliferation 77/3662 144/15509 8.00093e-15 3.51701e-13 2.11507e-13 NOX1/IGF1/CYBA/FGFR2/RHOA/NOTCH3/XRCC5/MMP2/PDGFB/MMP9/NDRG4/TGFB1/BMPR1A/RPS6KB1/IFNG/PPARD/HBEGF/IL12B/PDGFRB/STAT1/ID2/HDAC1/MFN2/TNFAIP3/NR4A3/GNA13/CDKN1A/BMP2/APOE/DNMT1/IL6/IL10/TLR4/CCN3/THBS1/FGF2/IGF1R/GNA12/IGFBP3/TCF7L2/IL18/GJA1/ADAMTS1/LDLRAP1/IL6R/TGFBR2/TERT/GPER1/NOS3/NDRG2/FRS2/PTAFR/S1PR1/DDIT3/JUN/CTNNBIP1/ERN1/ADIPOQ/RBM10/IRAK1/SRC/MAP3K5/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/ITGB3/CCL5/CCL5/ELANE/PTEN 77
GO:0002475 antigen processing and presentation via MHC class Ib 29/3662 33/15509 8.8953e-15 3.88261e-13 2.33493e-13 AP3D1/AP3B1/CD1A/CD1C/CD1B/TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-E/HLA-G/TAP2/HLA-E/TAP2/TAP2/HLA-E/HLA-E/HLA-G/TAP2/HLA-G/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/TAP2/B2M/HLA-G 29
GO:2001233 regulation of apoptotic signaling pathway 140/3662 328/15509 1.04715e-14 4.53863e-13 2.72945e-13 BAD/KDM1A/NOX1/MAPK8IP2/IGF1/SNAI2/CD74/HGF/FAS/CD44/BAK1/HERPUD1/TRAF1/NGFR/TMEM161A/SP100/HYAL2/CSNK2A2/TP63/FGFR1/PTPRC/GSK3B/BAX/DNM1L/ICAM1/TMEM14A/XBP1/MMP9/SRPX/GATA1/PYCARD/EYA1/SFRP1/IL7/URI1/GSDME/CASP2/HSPB1/SERPINE1/TGFBR1/CREB3/CXCL12/UNC5B/PPIF/SEPTIN4/RPS6KB1/CTSC/PTPMT1/EYA4/IL4/IL1A/PARK7/HDAC1/TNFAIP3/HELLS/CLU/TNFSF10/INHBA/EEF1E1/IL1B/RBCK1/PLAGL2/BECN1/TRAP1/STYXL1/BCL2L2/EPO/PSME3/SERINC3/ITM2C/THBS1/BCL2L10/ITGAV/COL2A1/TMBIM6/RB1/ARRB2/PMAIP1/SOD1/PARP1/NONO/TCF7L2/BCL2L11/NR4A2/FAIM/LMNA/ZNF385A/RPL26/WNT4/PEA15/ATF3/INHBB/PF4/PRKCD/TERT/CSF2/GPER1/NOS3/FXN/PRDX2/FADD/CX3CR1/PRELID1/TRIAP1/BCL2L1/FGG/FGA/SCG2/EIF2AK3/RELA/DDIT3/PTPN2/BDNF/GRINA/PAK2/PTTG1IP/NOG/PRKN/MUC1/ASAH2/FZD9/NOC2L/PPIA/SRC/TNF/TNF/NDUFS3/FIS1/MAGEA3/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC/AATF/MIF/PCGF2/PTEN 140
GO:0002262 myeloid cell homeostasis 80/3662 154/15509 2.01522e-14 8.67385e-13 5.2163e-13 SLC4A1/KMT2E/BTK/UFL1/ALAS1/BAK1/FOXP3/KCNQ1/HIPK2/SPI1/BAX/MTHFD1/ACIN1/GATA1/ERCC2/GPI/KLF1/JAK3/HAMP/HOXA5/GATA3/HOXB6/SLC11A2/SH2B3/MAPK14/RHAG/HSPA9/SMAD5/BCL6/STAT1/ID2/EPAS1/MPL/PRDX1/MYB/FOXO3/PTBP3/INHBA/THRA/PRMT1/ZFP36/EPO/ABCB10/IL6/IREB2/SLC15A4/RB1/SOD1/ARNT/DYRK3/NCAPG2/BCL2L11/MERTK/KIT/XKR8/FANCC/ALAS2/DMTN/TAL1/BAP1/CASP3/SFXN1/EPB42/INPP5D/AHSP/STAT5B/PTPN2/CXCR2/RPS17/CSF1/PDE4B/ZFP36L1/CDIN1/HMGB1/L3MBTL3/MAFB/PRKDC/B2M/INPP5D/GPI 80
GO:0048660 regulation of smooth muscle cell proliferation 75/3662 141/15509 2.57911e-14 1.10244e-12 6.62987e-13 NOX1/IGF1/CYBA/FGFR2/RHOA/NOTCH3/XRCC5/MMP2/PDGFB/MMP9/NDRG4/TGFB1/BMPR1A/RPS6KB1/IFNG/PPARD/HBEGF/IL12B/PDGFRB/STAT1/ID2/HDAC1/MFN2/TNFAIP3/NR4A3/GNA13/CDKN1A/BMP2/APOE/DNMT1/IL6/IL10/TLR4/THBS1/FGF2/IGF1R/GNA12/IGFBP3/TCF7L2/IL18/GJA1/ADAMTS1/LDLRAP1/IL6R/TGFBR2/TERT/GPER1/NOS3/NDRG2/FRS2/PTAFR/S1PR1/JUN/CTNNBIP1/ERN1/ADIPOQ/RBM10/IRAK1/SRC/MAP3K5/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/ITGB3/CCL5/CCL5/ELANE/PTEN 75
GO:0002437 inflammatory response to antigenic stimulus 53/3662 85/15509 2.72316e-14 1.15604e-12 6.95221e-13 BTK/KARS1/FCGR2B/MKRN2/IL5RA/HCK/GATA3/CD81/MAPK14/IL12B/PARK7/C3/CCR7/CD68/NOTCH2/IL2RA/IL10/IL1RN/FURIN/PLK2/NOTCH1/PSMB4/SYK/NOD2/RBPJ/A2M/CD28/CXCR2/ZP3/HMGB1/SRC/ELANE/TNF/HLA-E/TNF/HLA-E/LTA/TNF/HLA-E/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/LTA/TNF/HLA-E/HLA-E/LTA/ELANE 53
GO:0002863 positive regulation of inflammatory response to antigenic stimulus 28/3662 32/15509 3.33407e-14 1.40575e-12 8.45396e-13 BTK/KARS1/CD81/PARK7/C3/CCR7/CD28/ZP3/TNF/HLA-E/TNF/HLA-E/LTA/TNF/HLA-E/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/LTA/TNF/HLA-E/HLA-E/LTA 28
GO:0034612 response to tumor necrosis factor 107/3662 233/15509 4.87722e-14 2.0425e-12 1.22833e-12 SELE/BIRC3/FAS/TNFRSF1B/YTHDC2/TNFRSF17/CYBA/TRAF1/HYAL2/UBE2K/APOB/TCL1A/PCK2/NFKBIA/CD40/BIRC7/CCL22/CCL17/PYCARD/SFRP1/ASAH1/HAMP/GSDME/GATA3/RPS6KB1/CCL2/CALCA/KRT18/MAPK14/HES1/CCL20/STAT1/TNFAIP3/FOXO3/PTK2B/H2BC11/CD70/NR1D1/ZFP36/ASS1/AKAP12/EDA2R/TRAF3/PIAS3/CHI3L1/ADAMTS7/TANK/CCL21/IL18BP/THBS1/CYP1B1/TNFRSF11A/AFF3/TNFRSF21/COMMD7/ZFP36L2/TNFRSF13C/ADAMTS13/VCAM1/CASP3/GPER1/SYK/GPD1/NKIRAS2/ADAM9/CXCL8/LIMS1/FOS/CD14/CCL11/CCL19/RELA/PTPN2/ADIPOQ/TRAIP/CIB1/PRKN/ZFP36L1/TRPV1/MAP3K5/NKIRAS1/MBP/TNF/TMSB4X/TNF/CHUK/CPNE1/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/NAIP/CCL5/CCL5/PRPF8/CCL4/CCL18/CCL4/NAIP/CCL4/CCL18/CCL18/NAIP/ADAMTS13 107
GO:0001525 angiogenesis 190/3662 494/15509 5.04159e-14 2.09717e-12 1.2612e-12 ITGA2B/ADIPOR2/NOX1/E2F2/DCN/HGF/RNH1/GRN/SARS1/FLT4/ATP2B4/EPN1/NGFR/HIPK2/TIE1/FGFR2/SP100/PKM/RHOA/ROCK1/NOTCH3/MCAM/SIRT6/MMP2/APOH/ANGPT2/AGO1/ABL1/XBP1/MYH9/CD40/POFUT1/PPP1R16B/FLT1/TJP1/SFRP1/PRKD2/PIK3CG/HOXA5/HSPB1/SERPINE1/TGFBR1/ENG/UNC5B/CCL2/MDK/MAPK14/SMOC2/IL12B/PDGFRB/AMOTL2/WNT5A/IL1A/NCL/FN1/STAT1/PDCL3/EPAS1/LEPR/GADD45A/WARS2/CD160/FASLG/NRP2/TNFAIP3/PGF/GNA13/TEK/PTK2B/CXCR4/RECK/NR4A1/IL1B/C3/ID1/RRAS/KDR/PXDN/CHI3L1/EPHB2/BTG1/LOXL2/NOTCH2/PDGFRA/CEMIP2/SRPK2/GLUL/SPRY2/IL6/CCM2/IL10/CCN3/THBS1/CYP1B1/ITGAV/FGF2/ENPEP/EGF/WARS1/ITGAX/EPHA2/CCN1/RHOB/MEIS1/SLIT2/PLK2/NOTCH1/HMGA2/ITGB1/VEGFC/IL18/HHEX/DDAH1/PRKCA/ADAMTS1/CXCL13/NODAL/MMP14/RUNX1/SHC1/EMC10/PLCD3/JAK1/RBM15/TGFBR2/PF4/AIMP1/NAA15/AGGF1/TLR3/TERT/SHH/NOS3/SYK/CYBB/ANPEP/STIM1/RBPJ/CX3CR1/EFNA1/PTK2/CXCL8/SEMA3E/S1PR1/SCG2/EIF2AK3/CCL11/BSG/EGFL7/DAG1/CSPG4/RNF213/LEP/JUN/CXCR2/SETD2/ADGRB1/EPHB3/ANXA2/COL18A1/FOXO4/CIB1/HGS/THBS2/CXCR3/PARVA/NRARP/FKBPL/TNF/HLA-G/TNF/HLA-G/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/PDCD6/YJEFN3/ITGB3/AKT3/HLA-G/TJP1/PTEN 190
GO:0097191 extrinsic apoptotic signaling pathway 100/3662 213/15509 5.86655e-14 2.42406e-12 1.45779e-12 BAD/IGF1/SNAI2/HGF/FAS/TNFRSF1B/BAK1/TRAF1/ERBB3/SPI1/SP100/HYAL2/FGFR3/FGFR1/PTPRC/GSK3B/BAX/P2RX7/ICAM1/MKNK2/SRPX/GATA1/PYCARD/EYA1/SFRP1/IL7/TGFB1/GSK3A/CASP2/SERPINE1/TGFBR1/UNC5B/RPS6KB1/KRT18/IFNG/EYA4/IL4/IL1A/PARK7/FASLG/TNFAIP3/FOXO3/TNFRSF10B/TNFSF10/INHBA/IL1B/CD70/RBCK1/BCL2L2/PSME3/NGF/ITM2C/THBS1/BCL2L10/ITGAV/COL2A1/BCL2A1/PMAIP1/PIK3R1/TCF7L2/BAG3/BCL2L11/FAIM/IL6R/LMNA/PEA15/ATF3/PF4/ZDHHC3/TLR3/TERT/CSF2/GPER1/NOS3/PRDX2/FADD/BCL2L1/FGG/FGA/SCG2/RELA/PAK2/CIB1/DAPK1/SRC/TNF/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF/PTPRC/PTEN 100
GO:0002764 immune response-regulating signaling pathway 176/3662 449/15509 6.07597e-14 2.49396e-12 1.49983e-12 CD38/CD79B/BTK/TYROBP/CD22/LTF/BIRC3/BTN3A1/FOXP3/CYBA/PUM2/MAP2K4/FCGR2B/PTPRC/WDFY1/LAT2/BAX/SPG21/ESR1/BAG6/ABL1/NFKBIA/CD40/NFATC2/HCK/RIOK3/TLR8/MEFV/PYCARD/CSK/KCNN4/LILRB1/PRKD2/CD79A/CD33/NOD1/GATA3/MAPK8/C1QBP/MAP2K6/LPXN/CD81/PDE4D/ZAP70/CD160/TNFAIP3/NR4A3/EIF2B2/RBCK1/CCR7/NR1D1/IRF3/NECTIN2/TRAF3/AP3B1/PTPN22/CD36/TLR4/IRF4/DDX60/SLC15A4/CMTM3/ARRB2/TNFRSF21/CD8A/MS4A1/KIT/APPL1/SPPL3/ICOSLG/NLRX1/CLPB/GFI1/MAPKAPK2/CTLA4/PRKCD/TLR3/SYK/MBL2/BTNL9/NOD2/TNIP2/INPP5D/PTK2/CD14/PRKCE/RELA/HRAS/PTPN2/CD19/CD28/HLA-DQB1/LACC1/PAK2/CACNB4/IRAK1/PDE4B/BTN3A2/LILRB4/PLSCR1/HMGB1/TLR7/CD47/SRC/CR1/BAG6/TNF/HLA-G/HLA-DQB1/HLA-DQB1/TNF/MICB/HLA-A/HLA-A/HLA-G/HLA-DPB1/NCR3/HLA-DPB1/TNF/HLA-A/HLA-A/MICB/NCR3/HLA-DQB1/HLA-DPB1/HLA-A/MICB/TNF/BAG6/TNF/TNF/HLA-A/HLA-DPB1/BAG6/TNF/HLA-G/HLA-DPB1/HLA-DPB1/MICB/HLA-DQB1/MICB/HLA-A/HLA-DQB1/TNF/HLA-G/HLA-DQB1/BAG6/BAG6/HLA-G/HLA-A/HLA-G/NCR3/HLA-DPB1/NCR3/NCR3/HLA-G/HLA-DPB1/NCR3/MICB/NAIP/LSM14A/PTPRC/IKBKG/CD24/LILRB1/LILRB4/HLA-G/NAIP/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/NAIP/INPP5D/ITCH 176
GO:0002712 regulation of B cell mediated immunity 50/3662 79/15509 6.22251e-14 2.52073e-12 1.51592e-12 BTK/PARP3/FOXP3/FCGR2B/TBX21/MLH1/PTPRC/MSH2/CD40/FCER2/IL27RA/TGFB1/EXOSC3/NSD2/HPX/IL4/BCL6/SHLD2/C3/FOXJ1/NECTIN2/NDFIP1/IL10/SLC15A4/TNFSF13/NOD2/CD28/CD55/CR1/TNF/HLA-E/TNF/HLA-E/LTA/TNF/HLA-E/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/LTA/TNF/HLA-E/HLA-E/LTA/PTPRC 50
GO:0002889 regulation of immunoglobulin mediated immune response 50/3662 79/15509 6.22251e-14 2.52073e-12 1.51592e-12 BTK/PARP3/FOXP3/FCGR2B/TBX21/MLH1/PTPRC/MSH2/CD40/FCER2/IL27RA/TGFB1/EXOSC3/NSD2/HPX/IL4/BCL6/SHLD2/C3/FOXJ1/NECTIN2/NDFIP1/IL10/SLC15A4/TNFSF13/NOD2/CD28/CD55/CR1/TNF/HLA-E/TNF/HLA-E/LTA/TNF/HLA-E/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/LTA/TNF/HLA-E/HLA-E/LTA/PTPRC 50
GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib 23/3662 24/15509 6.73783e-14 2.71176e-12 1.6308e-12 TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-E/HLA-G/TAP2/HLA-E/TAP2/TAP2/HLA-E/HLA-E/HLA-G/TAP2/HLA-G/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/TAP2/HLA-G 23
GO:0033002 muscle cell proliferation 95/3662 199/15509 7.00766e-14 2.80216e-12 1.68517e-12 NOX1/IGF1/HGF/CYBA/FGFR2/RHOA/NOTCH3/TP73/XRCC5/MMP2/ABL1/PDGFB/MMP9/NDRG4/TGFB1/TGFBR1/BMPR1A/RPS6KB1/IFNG/PPARD/MAPK14/HBEGF/IL12B/PDGFRB/KPNA1/STAT1/ID2/HDAC1/MFN2/TNFAIP3/NR4A3/GNA13/CDKN1A/BMP2/APOE/DNMT1/IL6/IL10/TLR4/CCN3/THBS1/FGF2/IGF1R/GNA12/IGFBP3/NOTCH1/TCF7L2/IL18/GJA1/ADAMTS1/SKI/LDLRAP1/RUNX1/IL6R/SELENON/TGFBR2/TERT/SHH/GPER1/NOS3/NDRG2/FRS2/RBPJ/PTAFR/ZFPM2/CDK1/FOS/S1PR1/DDIT3/JUN/CTNNBIP1/ERN1/ADIPOQ/RBM10/NKX2-5/NOG/IRAK1/ARID2/SRC/MAP3K5/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/ITGB3/CCL5/CCL5/ELANE/PTEN 95
GO:0002637 regulation of immunoglobulin production 52/3662 84/15509 7.28511e-14 2.89443e-12 1.74066e-12 BTK/CD22/PARP3/FOXP3/FCGR2B/TBX21/MLH1/IL4R/PTPRC/MSH2/XBP1/CD40/CD40LG/IL27RA/GPI/TGFB1/EXOSC3/NSD2/HPX/IL4/IL5/BCL6/CD86/SHLD2/PKN1/NDFIP1/EPHB2/IL6/IL10/IL21/SLC15A4/TMBIM6/TNFSF13/CD28/CR1/TNF/HLA-E/TNF/HLA-E/TNF/HLA-E/TNF/TNF/TNF/HLA-E/TNF/HLA-E/TNF/HLA-E/HLA-E/PTPRC/GPI 52
GO:0045670 regulation of osteoclast differentiation 49/3662 77/15509 8.13993e-14 3.21346e-12 1.93252e-12 TYROBP/LTF/TFE3/RASSF2/SFRP1/LILRB1/IFNG/NEDD9/IL17A/IL12B/IL4/IAPP/LRRC17/PIAS3/NOTCH2/TLR4/TCTA/PIK3R1/POU4F2/POU4F1/KLF10/SLC9B2/TLR3/TNFRSF11B/INPP5D/FOS/CEBPB/ESRRA/GPR137/CSF1/LILRB4/MTOR/MAFB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D 49
GO:0010563 negative regulation of phosphorus metabolic process 154/3662 381/15509 1.24708e-13 4.89201e-12 2.94197e-12 SLC4A1/SPAG9/MVP/HGF/BAK1/IPO5/ROCK1/HYAL2/SIRT2/SIRT6/FBLN1/PTPRC/GSK3B/PIBF1/TMED2/PPP1R15A/BAX/RTRAF/FKBP1A/ABL1/GADD45B/PIK3IP1/PDGFB/GSKIP/BMP7/RASSF2/PPP1R16B/SMAD7/PARD6A/TSC2/PYCARD/CSK/SFRP1/URI1/TGFB1/GSK3A/HSPB1/ENG/DVL1/DKK1/CHORDC1/CORO1C/SH2B3/IFNG/PDE4D/PPP2CA/MACROH2A1/KAT2B/PRKAR2A/PARK7/GADD45A/TNFAIP3/PTPA/MASTL/TARDBP/CRY2/INHBA/PKN1/LRP1/CDKN1A/IL1B/BMP2/ATG14/STYXL1/AJUBA/CDKN1C/CBFA2T3/APOE/CEP85/VPS25/EPHB2/MEN1/PTPN22/APC/MICAL1/NIBAN1/SPRY2/SORL1/SMAD6/TARBP2/RB1/WARS1/ARRB2/ENSA/DUSP10/PARP1/CALM2/CTDSP1/SLIT2/BOD1/IGFBP3/NCAPG2/C9orf72/PARD3/HHEX/CNKSR3/UCHL1/GNAQ/PPP1R15B/DMTN/CALM3/CAMK2N1/PRKCD/DUSP7/CASP3/DDIT4/PKIG/RGS14/CTDSP2/PTPN2/CHMP6/ANKLE2/JUN/PLEC/TAF7/PAK2/ADIPOQ/NPM1/SLC8A1/NOG/CIB1/INPP5J/SOCS1/PRKN/NF2/LILRB4/HEXIM1/SPRY4/PPIA/SPRED2/TNF/PPP1R11/AKT1S1/IPO7/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/DBNDD2/CEBPA/PRKDC/PTPRC/CDKN1C/LILRB4/PIP4K2B/LILRB4/LILRB4/LRP6/PTEN/CHORDC1 154
GO:0043491 protein kinase B signaling 92/3662 192/15509 1.3154e-13 5.12756e-12 3.08363e-12 IGF1/F7/HYAL2/SIRT2/MKRN2/FGFR1/LRP2/NOX4/HSP90AB1/OSM/RASD2/CD40/TSC2/TGFB1/PIK3CG/MET/TGFBR1/ENG/GATA3/CSF3/RPS6KB1/C1QBP/CCL2/SH2B3/HBEGF/PPP2CA/PARK7/SFRP5/TEK/IAPP/IL1B/CCR7/RRAS/KDR/GDF15/SESN2/CHI3L1/SPRY2/CCL21/THBS1/FGF2/EGF/IGF1R/ARRB2/EPHA2/TPBG/EGFR/NTRK2/TCF7L2/SESN3/ITGB1/IL18/MERTK/THEM4/RICTOR/GPER1/CX3CR1/PTK2/OTUD3/CCL19/DAG1/LEP/DDIT3/CD28/CIB1/ZFP36L1/MAGI2/AKR1C3/SRC/NTRK1/MTOR/TNF/HLA-G/TNF/HLA-G/CPNE1/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/PDCD6/CCL5/CCL5/HLA-G/PTEN 92
GO:0002428 antigen processing and presentation of peptide antigen via MHC class Ib 24/3662 26/15509 1.65994e-13 6.43019e-12 3.86701e-12 TAP2/HLA-E/HLA-G/TAP2/TAP2/HLA-E/HLA-G/TAP2/HLA-E/TAP2/TAP2/HLA-E/HLA-E/HLA-G/TAP2/HLA-G/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/TAP2/B2M/HLA-G 24
GO:0046631 alpha-beta T cell activation 90/3662 187/15509 1.75334e-13 6.74982e-12 4.05922e-12 TMEM98/HFE/RUNX3/FOXP3/PRDM1/AP3D1/RHOA/CBFB/TBX21/IL4R/ARG2/PTPRC/IL12RB1/ABL1/SMAD7/ELF4/LILRB1/JAK3/TNFSF8/GATA3/ZBTB16/CD81/IFNG/IL12B/IL4/BCL6/CD86/ZAP70/CD160/MYB/CD80/BCL11B/TWSG1/NDFIP1/RARA/AP3B1/PTPN22/IL2RA/IL6/HLX/IRF4/IL21/ARMC5/IL2RG/IL18/RUNX1/IL6R/TGFBR2/SHH/SYK/LGALS9/CCL19/CD28/KLHL25/SOCS1/LILRB4/HMGB1/CD55/ENTPD7/MTOR/PNP/HLA-E/HLA-DRA/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-DRA/HLA-DRA/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-DRA/HLA-A/HLA-E/PTPRC/LILRB1/LILRB4/LILRB1/LILRB1/HLA-DRA/LILRB1/LILRB4/LILRB4/ITCH 90
GO:0048661 positive regulation of smooth muscle cell proliferation 53/3662 88/15509 2.09477e-13 8.01445e-12 4.81975e-12 NOX1/IGF1/CYBA/FGFR2/NOTCH3/MMP2/PDGFB/MMP9/TGFB1/BMPR1A/RPS6KB1/HBEGF/PDGFRB/STAT1/ID2/HDAC1/MFN2/NR4A3/DNMT1/IL6/IL10/TLR4/THBS1/FGF2/IGF1R/IL18/GJA1/ADAMTS1/LDLRAP1/IL6R/TGFBR2/TERT/FRS2/PTAFR/S1PR1/JUN/ERN1/IRAK1/SRC/MAP3K5/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/CCL5/CCL5/ELANE 53
GO:0045936 negative regulation of phosphate metabolic process 153/3662 380/15509 2.18462e-13 8.30691e-12 4.99563e-12 SLC4A1/SPAG9/MVP/HGF/BAK1/IPO5/ROCK1/HYAL2/SIRT2/SIRT6/FBLN1/PTPRC/GSK3B/PIBF1/TMED2/PPP1R15A/BAX/RTRAF/FKBP1A/ABL1/GADD45B/PIK3IP1/PDGFB/GSKIP/BMP7/RASSF2/PPP1R16B/SMAD7/PARD6A/TSC2/PYCARD/CSK/SFRP1/URI1/TGFB1/HSPB1/ENG/DVL1/DKK1/CHORDC1/CORO1C/SH2B3/IFNG/PDE4D/PPP2CA/MACROH2A1/KAT2B/PRKAR2A/PARK7/GADD45A/TNFAIP3/PTPA/MASTL/TARDBP/CRY2/INHBA/PKN1/LRP1/CDKN1A/IL1B/BMP2/ATG14/STYXL1/AJUBA/CDKN1C/CBFA2T3/APOE/CEP85/VPS25/EPHB2/MEN1/PTPN22/APC/MICAL1/NIBAN1/SPRY2/SORL1/SMAD6/TARBP2/RB1/WARS1/ARRB2/ENSA/DUSP10/PARP1/CALM2/CTDSP1/SLIT2/BOD1/IGFBP3/NCAPG2/C9orf72/PARD3/HHEX/CNKSR3/UCHL1/GNAQ/PPP1R15B/DMTN/CALM3/CAMK2N1/PRKCD/DUSP7/CASP3/DDIT4/PKIG/RGS14/CTDSP2/PTPN2/CHMP6/ANKLE2/JUN/PLEC/TAF7/PAK2/ADIPOQ/NPM1/SLC8A1/NOG/CIB1/INPP5J/SOCS1/PRKN/NF2/LILRB4/HEXIM1/SPRY4/PPIA/SPRED2/TNF/PPP1R11/AKT1S1/IPO7/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/DBNDD2/CEBPA/PRKDC/PTPRC/CDKN1C/LILRB4/PIP4K2B/LILRB4/LILRB4/LRP6/PTEN/CHORDC1 153
GO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling 50/3662 81/15509 2.58014e-13 9.75102e-12 5.86409e-12 WNT16/DCN/IGF1/HGF/ERBB3/FGFR1/OSM/PDGFB/FLT1/UNC5B/CSF3/PPARD/PDGFRB/FN1/TEK/CAT/FLT3/BECN1/KDR/PDGFRA/FGF2/EGF/IGF1R/PDGFC/NTRK2/IL18/KIT/GPER1/PTK2/SEMA3E/SELP/LEP/CD28/F2/F2R/ROR1/PRR5/SRC/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/CCL5/CCL5 50
GO:0046637 regulation of alpha-beta T cell differentiation 46/3662 72/15509 3.79861e-13 1.4269e-11 8.58111e-12 RUNX3/FOXP3/PRDM1/AP3D1/RHOA/CBFB/TBX21/IL4R/IL12RB1/SMAD7/JAK3/GATA3/ZBTB16/IFNG/IL12B/IL4/BCL6/CD86/ZAP70/MYB/CD80/RARA/AP3B1/HLX/IRF4/IL2RG/IL18/RUNX1/TGFBR2/SHH/SYK/LGALS9/CCL19/KLHL25/SOCS1/LILRB4/HMGB1/PNP/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/LILRB4/HLA-DRA/LILRB4/LILRB4 46
GO:0071356 cellular response to tumor necrosis factor 99/3662 216/15509 4.98598e-13 1.86163e-11 1.11955e-11 BIRC3/FAS/TNFRSF1B/TNFRSF17/CYBA/TRAF1/HYAL2/UBE2K/APOB/TCL1A/PCK2/NFKBIA/CD40/BIRC7/CCL22/CCL17/PYCARD/SFRP1/ASAH1/HAMP/GSDME/GATA3/CCL2/CALCA/KRT18/MAPK14/HES1/CCL20/STAT1/TNFAIP3/FOXO3/PTK2B/H2BC11/CD70/NR1D1/ZFP36/ASS1/AKAP12/EDA2R/TRAF3/PIAS3/CHI3L1/ADAMTS7/TANK/CCL21/IL18BP/THBS1/CYP1B1/TNFRSF11A/TNFRSF21/COMMD7/ZFP36L2/TNFRSF13C/ADAMTS13/VCAM1/GPER1/SYK/GPD1/NKIRAS2/CXCL8/LIMS1/FOS/CCL11/CCL19/RELA/PTPN2/ADIPOQ/TRAIP/CIB1/PRKN/ZFP36L1/TRPV1/MAP3K5/NKIRAS1/TNF/TMSB4X/TNF/CHUK/CPNE1/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/NAIP/CCL5/CCL5/PRPF8/CCL4/CCL18/CCL4/NAIP/CCL4/CCL18/CCL18/NAIP/ADAMTS13 99
GO:2001187 positive regulation of CD8-positive, alpha-beta T cell activation 23/3662 25/15509 6.52647e-13 2.42222e-11 1.45668e-11 RUNX3/CBFB/PTPN22/RUNX1/LILRB4/HLA-E/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-A/HLA-E/LILRB4/LILRB4/LILRB4 23
GO:0070997 neuron death 140/3662 343/15509 6.84905e-13 2.52681e-11 1.51958e-11 BAD/TYROBP/FAS/TNFRSF1B/GRN/HSPA5/NGFR/HIPK2/ERBB3/MAP2K4/RHOA/ROCK1/INPP5A/VPS35/FCGR2B/TP63/PICALM/GSK3B/BAX/SLC23A2/KDM2B/AARS1/MSH2/HSP90AB1/ABL1/MYBL2/ADNP/CHMP4B/IL27RA/GPI/GSK3A/CASP2/AIMP2/GATA3/UNC5B/DKK1/CSF3/CCL2/ZPR1/CCND1/MDK/IFNG/WNT5A/PARK7/FASLG/NENF/FOXO3/NR4A3/GPR75/EGR1/CLU/PTK2B/CNTFR/TMTC4/MAX/ELK1/KDR/APOE/EPO/KRAS/NGF/SRPK2/IL10/STXBP1/TLR4/TFAP2A/SORL1/MAP3K12/TMBIM6/RB1/ST8SIA2/MEAK7/ARRB2/SOD1/APP/PARP1/ARL6IP5/TNFRSF21/NONO/NTRK2/THRB/POU4F1/BCL2L11/NR4A2/BTG2/ITGB2/TBC1D24/CAPN2/CASP3/TERT/FOXQ1/CDK5/NSMF/FADD/DDIT4/CX3CR1/ITGAM/FOS/SEMA3E/BCL2L1/CEBPB/LIG4/HRAS/DDIT3/BDNF/CDK5R1/JUN/NQO1/F2R/CSF1/PRKN/DCC/CLN3/FZD9/SYNGAP1/MAP3K5/NTRK1/GPRASP3/TNF/AKT1S1/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF/NAIP/IKBKG/CCL5/CCL5/NAIP/NEFL/NAIP/GPI 140
GO:0045638 negative regulation of myeloid cell differentiation 53/3662 90/15509 7.49441e-13 2.74854e-11 1.65293e-11 PAF1/LTF/HMGB3/HOXA9/NFKBIA/SFRP1/LILRB1/HOXA5/ZBTB16/HSPA9/IL4/MYB/PTK2B/IAPP/INHBA/PRMT1/ZFP36/LRRC17/RARA/PIAS3/TLR4/CUL4A/SKIC8/MEIS1/TCTA/PIK3R1/GABPA/RBM15/PF4/TLR3/TNFRSF11B/INPP5D/GPR137/STAT5B/PTPN2/ADIPOQ/CIB1/ZFP36L1/LILRB4/MAFB/H4C15/H4C14/H4C12/LILRB1/LILRB4/LILRB1/H4C5/LILRB1/H4C4/LILRB1/LILRB4/LILRB4/INPP5D 53
GO:0051098 regulation of binding 142/3662 350/15509 8.10126e-13 2.95362e-11 1.77626e-11 KDM1A/PON1/HFE/IGF1/HIPK2/BTBD1/SP100/ROCK1/SIRT2/CDC42/PRKACA/MARK2/ADD2/ACTB/RAP1GAP/GSK3B/ZMPSTE24/BAX/ADD1/FKBP1A/HSP90AB1/ABL1/TFIP11/CYP2D6/PDGFB/NFKBIA/MMP9/ADNP/GATA1/ERCC2/DOT1L/TLE5/MED25/TGFB1/MET/TGFBR1/EDF1/DVL1/GATA3/MAPK8/DKK1/CSF3/IFNG/PPP2CA/NPHP3/WNT5A/HES1/ITGA4/PARK7/STMN1/IFIT2/TEX14/LRP1/USP9X/CDKN1A/BMP2/ID1/PIN1/LIF/APOE/RARA/PER2/PRMT7/MEN1/NGF/IL10/NCBP1/DERL1/IRF4/SORL1/EGF/TDG/TMBIM6/RB1/ARRB2/EIF4A3/SMAD4/APP/CARM1/SNAPIN/PARP1/CALM2/C9orf72/TCF7L2/HMGA2/POU4F2/POU4F1/ZNF618/SPPL3/SKI/LDLRAP1/EPB41/CALM3/PEX19/DISC1/PYGO2/SPTA1/PRKCD/C4orf3/TERT/CDK5/NSD1/GOLGA2/NMD3/ADRB2/ATP2A2/CTBP2/DDIT3/SMAD2/BDNF/JUN/CTNNBIP1/AURKB/ADIPOQ/PHLDA2/RGMA/ANXA2/NOG/EIF3C/SUMO3/PRKN/RNF220/H1-0/HMGB1/SRC/CSNK2B/TMSB4X/CPNE1/EBF2/CSNK2B/CSNK2B/CSNK2B/CSNK2B/NME1/CCPG1/CYP2D6/B2M/CYP2D6/CYP2D6/CYP2D6/CYP2D6/PRKACA 142
GO:0038034 signal transduction in absence of ligand 43/3662 66/15509 8.21615e-13 2.96068e-11 1.7805e-11 BAD/SNAI2/FAS/BAK1/ERBB3/FGFR1/GSK3B/BAX/MKNK2/SRPX/GATA1/EYA1/IL7/GSK3A/CASP2/UNC5B/EYA4/IL4/IL1A/FOXO3/INHBA/IL1B/BCL2L2/BCL2L10/ITGAV/COL2A1/BCL2A1/BAG3/BCL2L11/PF4/TERT/CSF2/PRDX2/FADD/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 43
GO:0097192 extrinsic apoptotic signaling pathway in absence of ligand 43/3662 66/15509 8.21615e-13 2.96068e-11 1.7805e-11 BAD/SNAI2/FAS/BAK1/ERBB3/FGFR1/GSK3B/BAX/MKNK2/SRPX/GATA1/EYA1/IL7/GSK3A/CASP2/UNC5B/EYA4/IL4/IL1A/FOXO3/INHBA/IL1B/BCL2L2/BCL2L10/ITGAV/COL2A1/BCL2A1/BAG3/BCL2L11/PF4/TERT/CSF2/PRDX2/FADD/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 43
GO:0002714 positive regulation of B cell mediated immunity 39/3662 57/15509 8.97447e-13 3.19677e-11 1.92248e-11 BTK/TBX21/MLH1/PTPRC/MSH2/CD40/FCER2/TGFB1/EXOSC3/NSD2/HPX/IL4/SHLD2/C3/NECTIN2/TNFSF13/NOD2/CD28/TNF/HLA-E/TNF/HLA-E/LTA/TNF/HLA-E/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/LTA/TNF/HLA-E/HLA-E/LTA/PTPRC 39
GO:0002891 positive regulation of immunoglobulin mediated immune response 39/3662 57/15509 8.97447e-13 3.19677e-11 1.92248e-11 BTK/TBX21/MLH1/PTPRC/MSH2/CD40/FCER2/TGFB1/EXOSC3/NSD2/HPX/IL4/SHLD2/C3/NECTIN2/TNFSF13/NOD2/CD28/TNF/HLA-E/TNF/HLA-E/LTA/TNF/HLA-E/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/LTA/TNF/HLA-E/HLA-E/LTA/PTPRC 39
GO:0002504 antigen processing and presentation of peptide or polysaccharide antigen via MHC class II 42/3662 64/15509 1.05129e-12 3.72336e-11 2.23917e-11 CD74/FCGR2B/PYCARD/ARL8B/THBS1/HLA-DQB1/HLA-DQA1/HLA-DOA/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DQA1/HLA-DQB1/HLA-DRA/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/B2M/HLA-DRA 42
GO:1901342 regulation of vasculature development 120/3662 282/15509 1.09043e-12 3.84006e-11 2.30934e-11 E2F2/DCN/HGF/RNH1/GRN/SARS1/ATP2B4/EPN1/HIPK2/TIE1/SP100/PKM/ROCK1/SIRT6/APOH/ANGPT2/AGO1/ABL1/XBP1/CD40/PPP1R16B/FLT1/TJP1/SFRP1/PRKD2/HOXA5/HSPB1/SERPINE1/ENG/MDK/SMOC2/WNT5A/IL1A/STAT1/PDCL3/GADD45A/WARS2/CD160/FASLG/TNFAIP3/PGF/TEK/PTK2B/CXCR4/RECK/IL1B/C3/ID1/RRAS/KDR/CHI3L1/BTG1/CEMIP2/GLUL/SPRY2/IL6/CCM2/IL10/THBS1/CYP1B1/FGF2/WARS1/ITGAX/EPHA2/RHOB/PLK2/HMGA2/ITGB1/VEGFC/HHEX/DDAH1/PRKCA/ADAMTS1/CXCL13/NODAL/RUNX1/EMC10/JAK1/WNT4/TGFBR2/PF4/AGGF1/TLR3/TERT/NOS3/CYBB/STIM1/CX3CR1/EFNA1/CXCL8/SEMA3E/CCL11/LEP/CXCR2/ADGRB1/FOXO4/HGS/THBS2/FKBPL/TNF/HLA-G/TNF/HLA-G/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/PDCD6/YJEFN3/ITGB3/AKT3/HLA-G/TJP1 120
GO:2001234 negative regulation of apoptotic signaling pathway 95/3662 207/15509 1.3361e-12 4.6786e-11 2.81363e-11 KDM1A/MAPK8IP2/IGF1/SNAI2/CD74/HGF/CD44/BAK1/HERPUD1/TMEM161A/CSNK2A2/GSK3B/BAX/ICAM1/TMEM14A/XBP1/MMP9/GATA1/EYA1/IL7/URI1/HSPB1/SERPINE1/TGFBR1/CREB3/CXCL12/UNC5B/PPIF/RPS6KB1/EYA4/IL4/IL1A/PARK7/HDAC1/TNFAIP3/HELLS/CLU/IL1B/TRAP1/BCL2L2/EPO/PSME3/THBS1/BCL2L10/ITGAV/COL2A1/TMBIM6/RB1/ARRB2/NONO/TCF7L2/NR4A2/FAIM/LMNA/ZNF385A/WNT4/PEA15/PF4/TERT/CSF2/NOS3/FXN/PRDX2/CX3CR1/PRELID1/TRIAP1/BCL2L1/FGG/FGA/SCG2/RELA/BDNF/GRINA/PTTG1IP/NOG/PRKN/MUC1/ASAH2/FZD9/NOC2L/PPIA/SRC/TNF/TNF/NDUFS3/MAGEA3/TNF/TNF/TNF/TNF/TNF/TNF/AATF/MIF/PCGF2 95
GO:0050866 negative regulation of cell activation 98/3662 216/15509 1.39098e-12 4.84341e-11 2.91274e-11 CD9/BTK/HFE/TYROBP/CD74/RUNX3/HMGB3/GRN/PARP3/FOXP3/SPI1/CBFB/FCGR2B/TBX21/IL4R/ARG2/PTPRC/PIBF1/PDGFB/CTSG/SMAD7/SFRP1/LILRB1/JAK3/MDK/SH2B3/IL4/BCL6/CD86/ID2/TNFAIP3/ARG1/CD80/INHBA/PKN1/NR1D1/TWSG1/FOXJ1/APOE/NDFIP1/SYT11/SFTPD/PTPN22/IL2RA/PDGFRA/SERPINE2/HLX/IL10/ADAMTS18/TNFRSF21/MERTK/RUNX1/CTLA4/PRKCD/CASP3/SHH/GPER1/NOS3/PRDX2/INPP5D/LGALS9/FGG/CEBPB/GLMN/RAG2/PTPN2/F2/MICA/SOCS1/LILRB4/CNR2/HMGB1/PDCD1LG2/NRARP/CR1/HLA-G/HLA-G/HLA-G/MICA/MICA/HLA-G/MICA/HLA-G/HLA-G/HLA-G/TNFRSF13B/PTPRC/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 98
GO:0010035 response to inorganic substance 187/3662 500/15509 1.58627e-12 5.49257e-11 3.30314e-11 BAD/MPO/PON1/HFE/PPP5C/HGF/CPS1/GLRX2/BAK1/CASR/CDH1/HSPA5/RAD51/ATP2B4/RASGRP2/APOB/ATRX/SLC25A24/MMP2/ADD1/P2RX7/ABL1/APEX1/MMP9/ADNP/BMP7/GPI/HAMP/GSK3A/MET/TFR2/EZH2/MAPK8/PPIF/AREG/CRYAB/CCND1/SLC11A2/CUTA/PPP2CA/PDGFRB/WNT5A/IL1A/SLC30A3/STAT1/IGFBP2/SDC1/PARK7/MTR/PRDX1/TNNT2/TNFAIP3/ARG1/FOXO3/PKD2/NR4A3/DNMT3A/PTK2B/CAT/RUNX2/SLC25A23/FOSB/CCR7/BECN1/TRAP1/KDR/CYP2E1/ASS1/PRKAA1/SYT11/LOXL2/CD36/NT5E/HNRNPA1/EDNRB/IL6/IL10/TFAP2A/IL18BP/THBS1/KHK/CYP1B1/CARF/CYP1A1/CYP1A2/IMPA2/EIF4A3/SOD1/APP/ADCY10/KCNH1/PKLR/PARP1/SYT2/RHOB/CALM2/CCNA2/EGFR/ALAD/FOXO1/BMP6/KIT/FANCC/PPP1R15B/DMTN/GART/CALM3/ADAMTS13/ALOX15/VCAM1/CAPN2/INHBB/FABP1/BAP1/PRKCD/CASP3/TERT/CSF2/SHH/ADCY1/TNFRSF11B/NOS3/FXN/TRPV6/CYBB/AQP3/VCP/CHP2/STIM1/PRDX2/ADAM9/AHCYL1/ARL13B/CDK1/FOS/CD14/NPTX1/FGG/FGA/GPHN/EIF2AK3/BSG/CCL19/RELA/LIG4/FOSL1/JUN/KCNJ10/PLEC/ERN1/CALR/NQO1/PLCB1/SLC8A1/PRKN/PLSCR1/AKR1C3/CACNA1H/SRC/DDI2/MAP3K5/MBP/NTRK1/ND6/ZNF277/GDI1/DAXX/DAXX/ZNF580/CHUK/SIPA1/CPNE1/DAXX/DAXX/DAXX/HBB/CEBPA/PDCD6/HP/PKLR/TXNIP/B2M/TRPV6/PCGF2/NEFL/ADAMTS13/GPI 187
GO:0002861 regulation of inflammatory response to antigenic stimulus 40/3662 60/15509 1.68819e-12 5.813e-11 3.49584e-11 BTK/KARS1/FCGR2B/MKRN2/HCK/CD81/MAPK14/IL12B/PARK7/C3/CCR7/IL10/FURIN/PLK2/PSMB4/SYK/NOD2/CD28/ZP3/SRC/TNF/HLA-E/TNF/HLA-E/LTA/TNF/HLA-E/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/LTA/TNF/HLA-E/HLA-E/LTA 40
GO:0045765 regulation of angiogenesis 118/3662 278/15509 2.06422e-12 7.06854e-11 4.2509e-11 E2F2/DCN/HGF/RNH1/GRN/SARS1/ATP2B4/EPN1/HIPK2/TIE1/SP100/PKM/ROCK1/SIRT6/APOH/ANGPT2/AGO1/ABL1/XBP1/CD40/PPP1R16B/FLT1/TJP1/SFRP1/PRKD2/HOXA5/HSPB1/SERPINE1/ENG/MDK/SMOC2/WNT5A/IL1A/STAT1/PDCL3/GADD45A/WARS2/CD160/FASLG/TNFAIP3/PGF/TEK/PTK2B/CXCR4/RECK/IL1B/C3/RRAS/KDR/CHI3L1/BTG1/CEMIP2/GLUL/SPRY2/IL6/CCM2/IL10/THBS1/CYP1B1/FGF2/WARS1/ITGAX/EPHA2/RHOB/PLK2/HMGA2/ITGB1/VEGFC/HHEX/DDAH1/PRKCA/ADAMTS1/CXCL13/NODAL/RUNX1/EMC10/JAK1/TGFBR2/PF4/AGGF1/TLR3/TERT/NOS3/CYBB/STIM1/CX3CR1/EFNA1/CXCL8/SEMA3E/CCL11/LEP/CXCR2/ADGRB1/FOXO4/HGS/THBS2/FKBPL/TNF/HLA-G/TNF/HLA-G/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/PDCD6/YJEFN3/ITGB3/AKT3/HLA-G/TJP1 118
GO:0009615 response to virus 146/3662 367/15509 2.33066e-12 7.93703e-11 4.77319e-11 MAP3K14/BIRC3/POU2F2/FOXP3/EIF2AK2/PUM2/HYAL2/TBX21/DDX1/MID2/PTPRC/OPRK1/ZMPSTE24/APOB/ATG16L1/BAX/MAVS/IL12RB1/MARCHF2/CD40/RIOK3/TLR8/CCL22/PYCARD/LILRB1/URI1/GSDME/HSPB1/AP1S1/GATA3/CXCL12/ACTA2/C1QBP/POU2AF1/IFNG/AICDA/MAPK14/IL12B/IL4/STAT1/ODC1/STMN1/TNFAIP3/VAMP8/IFIT2/GPAM/CLU/TRIM25/CXCR4/IL1B/IRF3/BECN1/IRF5/TRAF3/TRIM5/TRIM22/POLR3F/SERINC3/PTPN22/RPS15A/IL6/TANK/NCBP1/DDX60/PPM1B/SENP7/HERC5/IL21/TARBP2/CYP1A1/ITGAX/ARMC5/PMAIP1/LYST/HMGA2/NLRX1/POLR3K/CLPB/JAK1/TLR3/MBL2/HTRA1/TRIM44/FADD/DDIT4/IRF2/POLR3D/LGALS9/TRIM56/TRIM8/BCL2L1/CCL11/CCL19/CFL1/RELA/PDE12/BANF1/FOSL1/CALR/PRF1/DDX60L/SETD2/MICA/IFITM1/CARD9/PLSCR1/TLR7/PCBP2/SRC/ATG7/ATAD3A/IFNA1/TNF/TRIM13/TNF/MICB/CHUK/TNF/MICB/MICB/TNF/TNF/TNF/TNF/MICB/MICA/MICB/TNF/MICA/TRIM26/MICA/MICB/IL10RB/LSM14A/PTPRC/IKBKG/CCL5/CCL5/LILRB1/CCL4/CCL4/LILRB1/LILRB1/LILRB1/CCL4/ITCH 146
GO:1901214 regulation of neuron death 127/3662 307/15509 2.66044e-12 9.01059e-11 5.41881e-11 BAD/TYROBP/TNFRSF1B/GRN/HIPK2/ERBB3/MAP2K4/RHOA/ROCK1/INPP5A/VPS35/FCGR2B/PICALM/GSK3B/BAX/SLC23A2/KDM2B/AARS1/MSH2/HSP90AB1/ABL1/MYBL2/ADNP/CHMP4B/IL27RA/GPI/GSK3A/CASP2/AIMP2/GATA3/UNC5B/DKK1/CSF3/CCL2/ZPR1/CCND1/MDK/IFNG/WNT5A/PARK7/FASLG/NENF/FOXO3/NR4A3/GPR75/EGR1/CLU/PTK2B/CNTFR/ELK1/KDR/APOE/EPO/KRAS/NGF/SRPK2/IL10/STXBP1/TLR4/TFAP2A/SORL1/MAP3K12/ST8SIA2/MEAK7/ARRB2/SOD1/PARP1/NONO/NTRK2/POU4F1/BCL2L11/NR4A2/BTG2/ITGB2/TBC1D24/CAPN2/CASP3/TERT/FOXQ1/CDK5/NSMF/DDIT4/CX3CR1/ITGAM/FOS/SEMA3E/BCL2L1/CEBPB/LIG4/HRAS/DDIT3/BDNF/CDK5R1/JUN/NQO1/F2R/CSF1/PRKN/DCC/CLN3/FZD9/SYNGAP1/MAP3K5/NTRK1/GPRASP3/TNF/AKT1S1/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF/NAIP/IKBKG/CCL5/CCL5/NAIP/NEFL/NAIP/GPI 127
GO:0002768 immune response-regulating cell surface receptor signaling pathway 125/3662 301/15509 2.87569e-12 9.68669e-11 5.8254e-11 CD38/CD79B/BTK/TYROBP/CD22/BTN3A1/FOXP3/MAP2K4/FCGR2B/PTPRC/LAT2/BAX/SPG21/BAG6/ABL1/CD40/NFATC2/HCK/CSK/KCNN4/LILRB1/PRKD2/CD79A/GATA3/MAPK8/LPXN/CD81/PDE4D/ZAP70/CD160/NR4A3/EIF2B2/RBCK1/CCR7/NECTIN2/PTPN22/CMTM3/TNFRSF21/CD8A/MS4A1/KIT/APPL1/SPPL3/ICOSLG/CTLA4/PRKCD/SYK/MBL2/BTNL9/INPP5D/PTK2/PRKCE/RELA/HRAS/PTPN2/CD19/CD28/HLA-DQB1/PAK2/CACNB4/PDE4B/BTN3A2/LILRB4/PLSCR1/CD47/SRC/CR1/BAG6/HLA-G/HLA-DQB1/HLA-DQB1/MICB/HLA-A/HLA-A/HLA-G/HLA-DPB1/NCR3/HLA-DPB1/HLA-A/HLA-A/MICB/NCR3/HLA-DQB1/HLA-DPB1/HLA-A/MICB/BAG6/HLA-A/HLA-DPB1/BAG6/HLA-G/HLA-DPB1/HLA-DPB1/MICB/HLA-DQB1/MICB/HLA-A/HLA-DQB1/HLA-G/HLA-DQB1/BAG6/BAG6/HLA-G/HLA-A/HLA-G/NCR3/HLA-DPB1/NCR3/NCR3/HLA-G/HLA-DPB1/NCR3/MICB/PTPRC/IKBKG/CD24/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D 125
GO:2001185 regulation of CD8-positive, alpha-beta T cell activation 30/3662 39/15509 2.98603e-12 1.0004e-10 6.01623e-11 HFE/RUNX3/CBFB/LILRB1/PTPN22/RUNX1/SOCS1/LILRB4/HLA-E/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-A/HLA-E/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 30
GO:0051896 regulation of protein kinase B signaling 79/3662 163/15509 3.32409e-12 1.10767e-10 6.66135e-11 IGF1/F7/HYAL2/FGFR1/LRP2/NOX4/HSP90AB1/OSM/RASD2/TSC2/TGFB1/PIK3CG/MET/TGFBR1/ENG/GATA3/CSF3/C1QBP/SH2B3/HBEGF/PPP2CA/PARK7/SFRP5/TEK/IAPP/CCR7/RRAS/GDF15/CHI3L1/SPRY2/CCL21/THBS1/FGF2/EGF/IGF1R/ARRB2/EPHA2/TPBG/EGFR/NTRK2/TCF7L2/SESN3/ITGB1/IL18/RICTOR/GPER1/CX3CR1/PTK2/OTUD3/CCL19/DAG1/LEP/DDIT3/CD28/CIB1/MAGI2/AKR1C3/SRC/NTRK1/MTOR/TNF/HLA-G/TNF/HLA-G/CPNE1/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/PDCD6/HLA-G/PTEN 79
GO:0071900 regulation of protein serine/threonine kinase activity 143/3662 359/15509 3.50719e-12 1.16244e-10 6.99069e-11 DBF4/LTF/ATP2B4/IPO5/RHOA/HYAL2/ACTB/FGFR1/PTPRC/NOX4/P2RX7/CCNK/CDC6/HSP90AB1/ABL1/PDGFB/CDKN3/TCL1A/CD40/BMP7/CD40LG/FLT1/AXIN1/PYCARD/CSK/SFRP1/CCNE1/TGFB1/PIK3CG/EZH2/BMPR1A/BCCIP/DKK1/MAP2K6/CCND1/CHORDC1/GTF2H1/SH2B3/FZD10/IFNG/CCND3/CCNG1/PPP2CA/MACROH2A1/PDGFRB/KAT2B/WNT5A/PRKAR2A/CNPPD1/GADD45A/TNFAIP3/PKD2/CCNI/PTK2B/FLT3/CDKN1A/IL1B/BMP2/PKMYT1/AJUBA/CDKN1C/APOE/SESN2/CCNA1/MEN1/CCNB1/PSRC1/PTPN22/CCNH/APC/SPRY2/TLR4/SORL1/THBS1/HERC5/FGF2/EGF/MAP3K12/RB1/TNFRSF11A/DUSP10/CALM2/CCNA2/PDGFC/EGFR/HMGA2/HHEX/UCHL1/KIT/CALM3/DVL3/DBF4B/CCNL1/PRKCD/DUSP7/CASP3/RICTOR/SYK/NOD2/CDK12/ADAM9/PKIG/RGS14/ADRB2/CCL19/CKS1B/MST1/HRAS/FZD4/CCNE2/CDK5R1/ERN1/ADIPOQ/CSF1R/SLC8A1/IRAK1/CIB1/HGS/HEXIM1/SPRY4/SRC/MAP3K5/ELANE/TNF/IPO7/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/GH1/PTPRC/CD24/CDKN1C/LOC102724560/MIF/ELANE/LRP6/PTEN/CHORDC1 143
GO:0048545 response to steroid hormone 131/3662 321/15509 3.83159e-12 1.2632e-10 7.59668e-11 BAD/CD38/KDM1A/CRY1/RNF14/UFL1/CPS1/CYBA/PTPRU/PLPP1/RHOA/TP63/PIAS2/PGR/ESR1/RBFOX2/PCK2/BMP7/RBBP7/SFRP1/PLAT/URI1/GPI/TGFB1/GSK3A/ENG/ZMIZ1/RPS6KB1/DDX5/AREG/HSPA8/CCND1/MDK/PPARD/IGFBP2/KDM3A/SDC1/PARK7/HDAC1/PADI2/ARID1A/ARG1/FOXO3/SPP1/KLF9/NR4A3/CRY2/FLT3/PKN1/CNOT1/FOSB/NKX2-2/NR1D1/ZFP36/YWHAH/CDO1/EPO/ASS1/WBP2/IL6/IL10/IL1RN/THBS1/CYP1B1/IGF1R/CARM1/PARP1/CNOT9/SLIT2/ALAD/NOTCH1/POU4F2/ZFP36L2/BCL2L11/BMP6/NODAL/STC1/CALM3/PRMT2/SCNN1D/ATP1A1/TGFBR2/HEYL/CASP3/GPER1/CYBB/TRIM68/ABCA3/DDIT4/ADAM9/PTAFR/FOS/PAQR8/TADA3/CYP7B1/ESRRA/FOSL1/A2M/TYMS/TAF7/CALR/SSTR2/OXTR/ADIPOQ/PAPPA/SLIT3/ZFP36L1/UBE2L3/WNT7B/AKR1C3/SRC/KANK2/MBP/RXRB/TNF/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF/TXNIP/NEFL/PAGR1/GPI 131
GO:1903829 positive regulation of protein localization 161/3662 418/15509 3.90917e-12 1.28196e-10 7.70947e-11 BAD/CD38/ITGA3/TYROBP/IGF1/CENPQ/CASR/CDH1/EPHA3/NNAT/ATP2B4/NGFR/IPO5/HYAL2/VPS35/CSNK2A2/PRKACA/SIRT6/PCM1/NDC80/GSK3B/OXCT1/ACHE/DNM1L/MAVS/P2RX7/HSP90AB1/SH3GLB1/GZMB/PCK2/PARD6A/KCNN4/PDCD5/TGFB1/CD33/GSK3A/DVL1/MAPK8/PPP3CB/RANGRF/ZPR1/CD81/PSMD9/IFNG/NEDD9/PPARD/MAPK14/TMEM30A/APBB3/WNT5A/IL1A/PARK7/SERP1/TARDBP/LRP1/RAB38/ACSL3/SOX4/IL1B/ERGIC3/TMEM35A/MGAT3/RAC2/LIF/SESN2/DKC1/PRKAA1/SYT11/XPO4/EPHB2/LRP4/APC/CCT7/GLUL/NMT1/TLR4/ANP32B/NUMA1/SORL1/RDX/EGF/CLSTN3/MEAK7/CEP131/SAE1/EPHA2/PARP1/STAC/PIK3R1/EGFR/MSN/GLUD1/TCF7L2/ITGB1/VEGFC/BICD1/BAG3/BMP6/RER1/EPB41/ITGB2/PCNT/BAP1/PRKCD/TERT/SHH/GPER1/CDK5/CCT2/RIC3/CHP2/ADAM9/MFF/NMD3/ITGAM/CDK1/KIF5B/PRKCE/TRIM8/FGG/FGA/ORMDL3/EIF2AK3/LEP/LARP7/HRAS/CEP135/PDZK1/ATG13/CDK5R1/MIEF2/F2/NPM1/CACNB4/PTP4A3/CIB1/PRKN/STAC3/UBE2L3/CLN3/PPIA/SRC/UBL5/SLC5A3/HSPA1L/TNF/HSPA1L/TNF/FIS1/TNF/HSPA1L/TNF/TNF/TNF/TNF/TNF/HSPA1L/HSPA1L/PECAM1/SQSTM1/PRKACA 161
GO:0001933 negative regulation of protein phosphorylation 120/3662 287/15509 4.55577e-12 1.48614e-10 8.93738e-11 SPAG9/MVP/HGF/BAK1/IPO5/HYAL2/SIRT2/FBLN1/PTPRC/PIBF1/TMED2/BAX/RTRAF/ABL1/GADD45B/GSKIP/BMP7/RASSF2/SMAD7/PARD6A/TSC2/PYCARD/SFRP1/TGFB1/HSPB1/ENG/DVL1/DKK1/CHORDC1/CORO1C/SH2B3/IFNG/PDE4D/PPP2CA/MACROH2A1/KAT2B/PRKAR2A/PARK7/GADD45A/TNFAIP3/TARDBP/PKN1/LRP1/CDKN1A/IL1B/BMP2/ATG14/CDKN1C/APOE/CEP85/VPS25/EPHB2/MEN1/PTPN22/APC/MICAL1/NIBAN1/SPRY2/SORL1/SMAD6/TARBP2/RB1/WARS1/ARRB2/DUSP10/CALM2/CTDSP1/SLIT2/IGFBP3/NCAPG2/C9orf72/PARD3/HHEX/CNKSR3/UCHL1/GNAQ/PPP1R15B/DMTN/CALM3/CAMK2N1/PRKCD/DUSP7/CASP3/DDIT4/PKIG/RGS14/CTDSP2/PTPN2/CHMP6/JUN/PLEC/TAF7/PAK2/ADIPOQ/NPM1/SLC8A1/NOG/CIB1/INPP5J/SOCS1/PRKN/NF2/LILRB4/HEXIM1/SPRY4/PPIA/SPRED2/AKT1S1/IPO7/DBNDD2/CEBPA/PRKDC/PTPRC/CDKN1C/LILRB4/LILRB4/LILRB4/LRP6/PTEN/CHORDC1 120
GO:0097193 intrinsic apoptotic signaling pathway 118/3662 281/15509 4.87698e-12 1.58259e-10 9.51744e-11 BAD/KDM1A/NOX1/E2F2/SNAI2/CD74/CD44/TNFRSF1B/BAK1/USP28/HERPUD1/FNIP2/HIPK2/TMEM161A/TP63/MLH1/TP73/PPP1R15A/BAX/DNM1L/MSH2/BAG6/ABL1/XBP1/GSKIP/MMP9/PYCARD/NBN/URI1/GSDME/CASP2/HSPB1/CREB3/CXCL12/PPIF/SEPTIN4/DDX5/PTPMT1/PERP/PARK7/HDAC1/HELLS/CLU/TNFRSF10B/CDKN1A/PLAGL2/BECN1/TRAP1/DYRK2/STYXL1/CHAC1/BCL2L2/EPO/EDA2R/MYBBP1A/SERINC3/BCL2L10/CYP1B1/BRCA2/TMBIM6/CUL4A/BCL2A1/PMAIP1/SOD1/EPHA2/TP53BP2/PARP1/ARL6IP5/PIK3R1/NONO/ITPR1/POU4F2/POU4F1/BCL2L11/ZNF385A/RPL26/PRKCD/SHISA5/CASP3/DDIT4/HINT1/TRIAP1/BCL2L1/EIF2AK3/CEBPB/BRSK2/HRAS/DDIT3/PTPN2/ERN1/GRINA/PTTG1IP/CHEK2/PRKN/MUC1/NOC2L/PPIA/SRC/MAP3K5/BAG6/TNF/TNF/NDUFS3/FIS1/MAGEA3/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/PRKDC/CD24/MIF 118
GO:0030335 positive regulation of cell migration 183/3662 493/15509 5.90405e-12 1.9059e-10 1.14618e-10 ITGA3/SPAG9/IGF1/SNAI2/CD74/HGF/GRN/FLT4/HSPA5/SYNE2/F7/CCAR1/MYLK/SPI1/RHOA/MCAM/FGFR1/PTPRC/CEACAM6/MMP2/DNM1L/ICAM1/ZNF268/ABL1/XBP1/PDGFB/MMP9/CD40/BMP7/FERMT1/FLT1/PYCARD/RAB11A/TJP1/SYDE1/GPI/PRKD2/TGFB1/PIK3CG/PTN/MET/HSPB1/SERPINE1/TGFBR1/CREB3/GATA3/CXCL12/ACTA2/RPS6KB1/C1QBP/MDK/WNT5B/IFNG/NEDD9/FBXO5/PTP4A1/SMOC2/HBEGF/IL4/PDGFRB/WNT5A/IL1A/CCL20/ITGA4/FN1/NRP2/NR4A3/PGF/TEK/PTK2B/CXCR4/IL1B/BMP2/CCR7/RRAS/STAT5A/KDR/RAC2/PODXL/AKAP12/EPHB2/PDGFRA/APC/SPRY2/IL6/TLR4/CCL21/ARHGEF39/MMP7/RDX/THBS1/CYP1B1/ITGAV/FGF2/EGF/IGF1R/ITGAX/GRB7/APP/EPHA2/CCN1/ABL2/RHOB/PDGFC/PLK2/PIK3R1/EGFR/NOTCH1/ITGB1/VEGFC/PRKCA/ADAMTS1/CXCL13/MMP14/KIT/DMTN/IL6R/EMC10/TBC1D24/S100A11/TGFBR2/TERT/CSF2/GPER1/NOS3/NSMF/MAPRE2/FADD/CX3CR1/ADAM9/SEMA4C/LGALS9/PTK2/PTAFR/CXCL8/ELP5/SEMA3E/S1PR1/PRKCE/CCL11/CCL19/SELP/HRAS/FZD4/JUN/CALR/CXCR2/FAM83H/F2R/CSF1R/SLC8A1/ZNF703/CSF1/FOXO4/CIB1/ZP3/HMGB1/FUT4/CD47/SRC/MTOR/TNF/TMSB4X/TNF/ZNF580/TNF/TNF/TNF/TNF/TNF/TNF/PDCD6/ITGB3/PECAM1/PTPRC/CCL5/CCL5/AKT3/CCL4/CCL4/TJP1/CCL4/GPI 183
GO:0045860 positive regulation of protein kinase activity 152/3662 391/15509 6.87141e-12 2.20669e-10 1.32706e-10 DBF4/CD4/LTF/IGF1/SLC11A1/ATP2B4/ERBB3/RHOA/MARK2/TRAF4/FGFR1/XRCC5/PTPRC/DLG3/PIBF1/NOX4/TPX2/P2RX7/CCNK/CDC6/HSP90AB1/ABL1/PDGFB/TCL1A/CD40/ADNP/CDC25B/RASSF2/CD40LG/FLT1/AXIN1/CSK/TGFB1/PIK3CG/EZH2/BMPR1A/DKK1/MAP2K6/UNC119/AREG/CCND1/CALCA/FZD10/IFNG/NEDD9/CCND3/HBEGF/IL12B/IL4/PPP2CA/PDGFRB/CD86/WNT5A/MOB1A/PARK7/PKD2/EGR1/CLU/TNFRSF10B/PTK2B/FLT3/CDKN1A/IL1B/BMP2/CCR7/AJUBA/EPO/CHI3L1/CCNB1/PSRC1/BORA/SPRY2/TLR4/CCL21/THBS1/FGF2/CENPE/EGF/MAP3K12/TNFRSF11A/CCN1/CALM2/PDGFC/EGFR/VLDLR/HMGA2/VEGFC/IL18/CACUL1/KIT/CALM3/IL6R/MRNIP/DVL3/DBF4B/TGFBR2/PRKCD/RICTOR/TLR3/CDK5/SYK/NOD2/ADAM9/EFNA1/ADRB2/PTK2/GPRC5C/ALK/MOB3A/CCL19/CKS1B/DAG1/LEP/HRAS/FZD4/CDK5R1/ERN1/PAK2/ADIPOQ/NPM1/CSF1R/ADRA2C/IRAK1/CSF1/CIB1/SOCS1/PPIA/SRC/MAP3K5/ELANE/MTOR/TNF/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF/ITGB3/GH1/PTPRC/CCL5/CD24/CCL5/MIF/ELANE 152
GO:1902532 negative regulation of intracellular signal transduction 175/3662 467/15509 6.92867e-12 2.2136e-10 1.33122e-10 KDM1A/ITGA3/PAFAH1B1/CD22/SNAI2/CD74/CD44/HERPUD1/ATP2B4/TMEM161A/SPI1/RHOA/HYAL2/RPS6KA6/MKRN2/FBLN1/PTPRC/GSK3B/MECOM/SEH1L/MAPKAPK5/P2RX7/PEBP1/ESR1/ABL1/PIK3IP1/XBP1/MMP9/BMP7/RASSF2/RIOK3/MGRN1/NPRL3/TSC2/PYCARD/CSK/SFRP1/URI1/YJU2/GSK3A/MET/HSPB1/FKTN/AMBP/CREB3/CXCL12/PPIF/RNF167/C1QBP/FOXM1/SH2B3/MAPK14/PDE4D/PPP2CA/BCL6/STAT1/FHL2/PARK7/HDAC1/ASH1L/MFN2/STMN1/TNFAIP3/HELLS/SFRP5/CLU/IL1B/BMP2/NR1D1/PRMT1/TRAP1/DYRK2/PIN1/LIF/BCL2L2/AJUBA/APOE/EPO/SESN2/PRKAA1/EPHB2/MEN1/PTPN22/SERPINE2/SPRY2/TANK/TLR4/CCN3/SORL1/THBS1/BCL2L10/PPM1B/DUSP5/TMBIM6/IGF1R/ARRB2/SMAD4/EPHA2/ABL2/DYRK3/DUSP10/SLIT2/NONO/SESN3/ITGB1/FOXO1/ITPR1/NDUFC2/CNKSR3/UCHL1/DUSP2/ADIPOR1/ARHGAP35/NLRX1/ZNF385A/ATF3/RNF149/PRKCD/DUSP7/GPER1/ARHGAP12/NDRG2/DDIT4/RHOH/RGS14/EFNA1/OTUD3/TRIAP1/BCL2L1/PDE3A/RELA/DAG1/KCTD13/DDIT3/PTPN2/GRINA/ADIPOQ/PTTG1IP/CHEK2/CIB1/PRKN/MUC1/NF2/LILRB4/C1QL4/MAGI2/SPRY4/NOC2L/PPIA/SRC/SYNGAP1/SPRED2/MTOR/HLA-G/AKT1S1/TMSB4X/HLA-G/NDUFS3/CPNE1/MAGEA3/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/PDCD6/PTPRC/LILRB4/HLA-G/MIF/LILRB4/LILRB4/RASA3/PTEN/ITCH 175
GO:0051250 negative regulation of lymphocyte activation 79/3662 165/15509 7.30993e-12 2.32338e-10 1.39724e-10 BTK/HFE/TYROBP/CD74/RUNX3/HMGB3/PARP3/FOXP3/CBFB/FCGR2B/TBX21/IL4R/ARG2/PIBF1/CTSG/SMAD7/SFRP1/LILRB1/JAK3/MDK/IL4/BCL6/CD86/ID2/TNFAIP3/ARG1/CD80/INHBA/PKN1/TWSG1/FOXJ1/NDFIP1/SFTPD/PTPN22/IL2RA/HLX/IL10/TNFRSF21/MERTK/RUNX1/CTLA4/CASP3/SHH/PRDX2/INPP5D/LGALS9/CEBPB/GLMN/RAG2/PTPN2/MICA/SOCS1/LILRB4/HMGB1/PDCD1LG2/NRARP/CR1/HLA-G/HLA-G/HLA-G/MICA/MICA/HLA-G/MICA/HLA-G/HLA-G/HLA-G/TNFRSF13B/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 79
GO:0050900 leukocyte migration 147/3662 375/15509 7.34724e-12 2.32338e-10 1.39724e-10 ITGAL/ITGA3/PAFAH1B1/SELE/CD9/CD74/F7/SPI1/RHOA/ROCK1/CDC42/WDR1/TBX21/ADD2/MMP2/DNM1L/ICAM1/ABL1/PDGFB/MYH9/CTSG/MMP9/HCK/FLT1/CCL22/CCL17/PYCARD/IL27RA/PIK3CG/PTN/SERPINE1/CREB3/GATA3/CXCL12/C1QBP/CCL2/MDK/CD81/CALCA/NEDD9/IL17A/IL4/WNT5A/IL1A/CCL20/ZAP70/ITGA4/PADI2/CSF3R/PGF/PTK2B/CXCR4/NUP85/IL1B/CCR7/SBDS/RAC2/MTUS1/FOXJ1/SFTPD/EDNRB/IL6/IL10/CCN3/CCL21/THBS1/CYP19A1/TNFRSF11A/APP/ABL2/LYST/SLIT2/PIK3R1/MSN/ITGB1/VEGFC/CXCL13/MMP14/KIT/ITGB2/CXCR5/IL6R/CCR5/VCAM1/CXCR1/PF4/AIMP1/SYK/NOD2/FADD/CX3CR1/RHOH/LGALS9/PTK2/PTAFR/CXCL8/S1PR1/SCG2/CCL11/BSG/IL16/CCL19/CYP7B1/STAT5B/SELP/LEP/PLEC/CALR/CXCR2/CSF1R/PLCB1/CSF1/PDE4B/CXCR3/ZP3/CNR2/HMGB1/PPIA/FUT4/PRTN3/CD47/SRC/ELANE/DPP4/TNF/CD177/TNF/ZNF580/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/PECAM1/CCL5/CCL5/CCL4/CCL18/CCL4/MIF/ELANE/PRTN3/CCL4/CCL18/CCL18 147
GO:1901216 positive regulation of neuron death 53/3662 94/15509 7.99051e-12 2.51397e-10 1.51186e-10 BAD/TYROBP/GRN/MAP2K4/RHOA/FCGR2B/PICALM/GSK3B/BAX/ABL1/MYBL2/GSK3A/CASP2/AIMP2/DKK1/IFNG/WNT5A/FASLG/FOXO3/EGR1/CLU/ELK1/SRPK2/TLR4/TFAP2A/ST8SIA2/PARP1/POU4F1/BCL2L11/ITGB2/CAPN2/CASP3/CDK5/DDIT4/ITGAM/FOS/DDIT3/CDK5R1/NQO1/MAP3K5/TNF/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF 53
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II 40/3662 62/15509 8.2411e-12 2.56726e-10 1.5439e-10 CD74/FCGR2B/PYCARD/HLA-DQB1/HLA-DQA1/HLA-DOA/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DQA1/HLA-DQB1/HLA-DRA/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/B2M/HLA-DRA 40
GO:0042113 B cell activation 110/3662 258/15509 8.24273e-12 2.56726e-10 1.5439e-10 BAD/CD38/CD79B/ST3GAL1/BTK/TYROBP/CD22/CD74/HMGB3/BAK1/PARP3/FOXP3/SPI1/KLF6/TCF3/FCGR2B/TBX21/MLH1/PTPRC/LAT2/BAX/MSH2/ABL1/XBP1/CD40/NFATC2/CD40LG/NBN/SFRP1/IL7/LYL1/IL27RA/TGFB1/CD79A/JAK3/EZH2/AHR/EXOSC3/NSD2/CD81/POU2AF1/AICDA/IL4/IL5/BCL6/CD86/ZAP70/ITGA4/ID2/TNFAIP3/PTK2B/FLT3/SHLD2/INHBA/PKN1/CDKN1A/CD70/FOXJ1/NDFIP1/EPHB2/NOTCH2/AKIRIN2/IL6/IL10/TLR4/IL21/SLC15A4/IRF8/DCAF1/PIK3R1/TNFRSF21/IL2RG/ITGB1/ZFP36L2/HHEX/MS4A1/MMP14/KIT/TNFRSF13C/ICOSLG/CXCR5/TNFSF13/VCAM1/CTLA4/PRKCD/CASP3/SYK/RAG1/NOD2/RBPJ/TNIP2/INPP5D/STAT5B/LIG4/RAG2/PTPN2/CD19/CD28/ZFP36L1/FZD9/PAX5/IFNA1/NTRK1/CR1/TNFRSF13B/PRKDC/PTPRC/MIF/INPP5D/PTEN 110
GO:0045591 positive regulation of regulatory T cell differentiation 28/3662 36/15509 1.00552e-11 3.11612e-10 1.87398e-10 FOXP3/IFNG/BCL6/FOXO3/DUSP10/IL2RG/LGALS9/KAT5/KLHL25/SOCS1/LILRB4/CR1/HLA-G/HLA-DRA/HLA-G/HLA-DRA/HLA-DRA/HLA-G/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4 28
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II 39/3662 60/15509 1.06366e-11 3.27989e-10 1.97247e-10 CD74/FCGR2B/HLA-DQB1/HLA-DQA1/HLA-DOA/HLA-DQB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DPB1/HLA-DRA/HLA-DQA1/HLA-DRA/HLA-DPB1/HLA-DPB1/HLA-DPB1/HLA-DRB4/HLA-DQB1/HLA-DPA1/HLA-DQA1/HLA-DQB1/HLA-DQA1/HLA-DQA1/HLA-DQB1/HLA-DRA/HLA-DQA1/HLA-DPB1/HLA-DQA1/HLA-DPB1/HLA-DQA1/B2M/HLA-DRA 39
GO:0070371 ERK1 and ERK2 cascade 125/3662 306/15509 1.10408e-11 3.38766e-10 2.03728e-10 CD4/IGF1/CD74/CD44/CASR/FLT4/KARS1/FGFR2/FGFR3/RPS6KA6/FBLN1/PTPRC/NOX4/ICAM1/ABL1/PDGFB/CCL22/CCL17/NDRG4/PYCARD/CSK/PRKD2/TGFB1/NOD1/ACTA2/CCL2/PDGFRB/IL1A/CCL20/FN1/TEK/PTK2B/INHBA/IL1B/BMP2/CCR7/RRAS/PIN1/KDR/LIF/APOE/EPO/AKAP12/CHI3L1/EPHB2/PTPN22/NOTCH2/PDGFRA/CD36/SPRY2/TLR4/CCL21/DUSP5/ITGAV/FGF2/EGF/MAP3K12/ARRB2/SMAD4/TNFRSF11A/APP/EPHA2/CCN1/DUSP10/PDGFC/TPBG/EGFR/NOTCH1/ZFP36L2/CNKSR3/PRKCA/NODAL/SHC1/ALOX15/ATF3/DUSP7/GPER1/SYK/NDRG2/FRS2/NOD2/LGALS9/RGS14/CDK1/FGG/FGA/CCL11/CCL19/HRAS/PTPN2/JUN/PTPN11/OXTR/ADIPOQ/F2R/CSF1R/CIB1/ZFP36L1/C1QL4/SPRY4/CARD9/HMGB1/SRC/SPRED2/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/PTPRC/CCL5/CCL5/CCL4/CCL18/CCL4/MIF/CCL4/CCL18/CCL18/PTEN 125
GO:0007162 negative regulation of cell adhesion 116/3662 278/15509 1.21175e-11 3.69972e-10 2.22495e-10 CD9/HFE/SNAI2/CD74/RUNX3/CDH1/FOXP3/ERBB3/SPI1/RHOA/CBFB/FCGR2B/TBX21/PLXNA2/IL4R/FBLN1/ARG2/PTPRC/MMP2/ANGPT2/ABL1/CTSG/SMAD7/LILRB1/TGFB1/JAK3/SERPINE1/AKNA/CXCL12/LPXN/MDK/CORO1C/SH2B3/IL4/BCL6/CD86/ARG1/CD80/BMP2/PODXL/TWSG1/FOXJ1/ASS1/NDFIP1/EPHB2/SFTPD/MEN1/PTPN22/IL2RA/SERPINE2/HLX/IL10/IL1RN/CCL21/RDX/THBS1/CYP1B1/ADAMTS18/ARHGDIA/TBCD/PIK3R1/TNFRSF21/NOTCH1/BMP6/MMP14/DMTN/RUNX1/CTLA4/PRKCD/MELTF/CASP3/SHH/PRDX2/LGALS9/PTK2/SEMA3E/FGG/CEBPB/FZD4/GLMN/RAG2/PTPN2/RCC2/PTPN11/ADIPOQ/ZNF703/SOCS1/MUC1/NF2/LILRB4/SPRY4/HMGB1/SRC/PDCD1LG2/MBP/NRARP/CR1/HLA-G/HLA-G/SIPA1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/PTPRC/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/PTEN/ITCH 116
GO:0046638 positive regulation of alpha-beta T cell differentiation 37/3662 56/15509 1.73906e-11 5.28369e-10 3.17752e-10 RUNX3/FOXP3/AP3D1/RHOA/CBFB/IL4R/IL12RB1/ZBTB16/IFNG/IL12B/CD86/ZAP70/MYB/CD80/RARA/AP3B1/HLX/IL2RG/IL18/RUNX1/TGFBR2/SHH/SYK/LGALS9/CCL19/KLHL25/SOCS1/LILRB4/PNP/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/LILRB4/HLA-DRA/LILRB4/LILRB4 37
GO:0061081 positive regulation of myeloid leukocyte cytokine production involved in immune response 31/3662 43/15509 2.33955e-11 7.07344e-10 4.25384e-10 CD74/DDX1/MAVS/P2RX7/PYCARD/LILRB1/NOD1/WNT5A/NR4A3/CD36/TLR4/KIT/MAPKAPK2/TLR3/SYK/NOD2/CARD9/TLR7/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/HLA-G/LILRB1/MIF/LILRB1/LILRB1 31
GO:0002507 tolerance induction 35/3662 52/15509 2.75917e-11 8.30161e-10 4.99244e-10 FOXP3/CLC/TNFAIP3/FOXJ1/IL2RA/XKR8/TGFBR2/LGALS9/CCR4/LILRB4/HMGB1/HLA-E/HLA-G/HLA-B/HLA-E/HLA-G/HLA-B/HLA-B/HLA-E/HLA-B/HLA-E/HLA-E/HLA-G/HLA-B/HLA-G/HLA-E/HLA-G/HLA-G/HLA-E/HLA-G/LILRB4/HLA-G/LILRB4/LILRB4/ITCH 35
GO:0032640 tumor necrosis factor production 77/3662 163/15509 3.08869e-11 9.20371e-10 5.53495e-10 BTK/TYROBP/LTF/IGF1/FOXP3/CYBA/ARG2/PTPRC/MAVS/ACP5/PYCARD/LILRB1/IL27RA/CD33/NOD1/HSPB1/IFNG/IL17A/IL12B/IL4/WNT5A/IL1A/TNFAIP3/CLU/TNFRSF8/ZFP36/AKAP12/RARA/SYT11/EPHB2/PTPN22/CD36/IL6/IL10/TLR4/THBS1/ARRB2/APP/PIK3R1/MAPKAPK2/PF4/TLR3/SYK/CYBB/NOD2/FADD/CX3CR1/LGALS9/PTAFR/CD14/CCL19/LEP/LPL/PTPN11/ADIPOQ/LILRB4/CARD9/HMGB1/CD47/UBE2J1/HLA-E/HLA-E/HLA-E/HLA-E/ORM1/HLA-E/HLA-E/HLA-E/PTPRC/LILRB1/LILRB4/LILRB1/MIF/LILRB1/LILRB1/LILRB4/LILRB4 77
GO:0032680 regulation of tumor necrosis factor production 77/3662 163/15509 3.08869e-11 9.20371e-10 5.53495e-10 BTK/TYROBP/LTF/IGF1/FOXP3/CYBA/ARG2/PTPRC/MAVS/ACP5/PYCARD/LILRB1/IL27RA/CD33/NOD1/HSPB1/IFNG/IL17A/IL12B/IL4/WNT5A/IL1A/TNFAIP3/CLU/TNFRSF8/ZFP36/AKAP12/RARA/SYT11/EPHB2/PTPN22/CD36/IL6/IL10/TLR4/THBS1/ARRB2/APP/PIK3R1/MAPKAPK2/PF4/TLR3/SYK/CYBB/NOD2/FADD/CX3CR1/LGALS9/PTAFR/CD14/CCL19/LEP/LPL/PTPN11/ADIPOQ/LILRB4/CARD9/HMGB1/CD47/UBE2J1/HLA-E/HLA-E/HLA-E/HLA-E/ORM1/HLA-E/HLA-E/HLA-E/PTPRC/LILRB1/LILRB4/LILRB1/MIF/LILRB1/LILRB1/LILRB4/LILRB4 77
GO:0070374 positive regulation of ERK1 and ERK2 cascade 92/3662 208/15509 3.8017e-11 1.12741e-09 6.78007e-10 CD4/IGF1/CD74/CD44/CASR/FLT4/FGFR2/FGFR3/PTPRC/NOX4/ICAM1/ABL1/PDGFB/CCL22/CCL17/NDRG4/PYCARD/PRKD2/TGFB1/NOD1/ACTA2/CCL2/PDGFRB/IL1A/CCL20/TEK/PTK2B/INHBA/BMP2/CCR7/KDR/APOE/EPO/AKAP12/CHI3L1/PTPN22/NOTCH2/PDGFRA/CD36/SPRY2/TLR4/CCL21/FGF2/MAP3K12/ARRB2/TNFRSF11A/APP/PDGFC/TPBG/EGFR/NOTCH1/PRKCA/NODAL/SHC1/ALOX15/GPER1/NOD2/LGALS9/FGG/FGA/CCL11/CCL19/HRAS/JUN/PTPN11/F2R/CSF1R/CIB1/CARD9/HMGB1/SRC/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/PTPRC/CCL5/CCL5/CCL4/CCL18/CCL4/MIF/CCL4/CCL18/CCL18/PTEN 92
GO:0002701 negative regulation of production of molecular mediator of immune response 37/3662 57/15509 3.82937e-11 1.13021e-09 6.79688e-10 HFE/CD22/PARP3/FOXP3/FCGR2B/TBX21/SMAD7/ACP5/LILRB1/TGFB1/JAK3/BCL6/ARG1/NDFIP1/IL10/TMBIM6/CD96/NLRX1/NOD2/PRG2/LILRB4/CR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 37
GO:0042326 negative regulation of phosphorylation 130/3662 327/15509 3.95624e-11 1.16212e-09 6.98881e-10 SLC4A1/SPAG9/MVP/HGF/BAK1/IPO5/ROCK1/HYAL2/SIRT2/SIRT6/FBLN1/PTPRC/PIBF1/TMED2/BAX/RTRAF/ABL1/GADD45B/PIK3IP1/GSKIP/BMP7/RASSF2/SMAD7/PARD6A/TSC2/PYCARD/CSK/SFRP1/TGFB1/HSPB1/ENG/DVL1/DKK1/CHORDC1/CORO1C/SH2B3/IFNG/PDE4D/PPP2CA/MACROH2A1/KAT2B/PRKAR2A/PARK7/GADD45A/TNFAIP3/TARDBP/INHBA/PKN1/LRP1/CDKN1A/IL1B/BMP2/ATG14/AJUBA/CDKN1C/CBFA2T3/APOE/CEP85/VPS25/EPHB2/MEN1/PTPN22/APC/MICAL1/NIBAN1/SPRY2/SORL1/SMAD6/TARBP2/RB1/WARS1/ARRB2/DUSP10/CALM2/CTDSP1/SLIT2/IGFBP3/NCAPG2/C9orf72/PARD3/HHEX/CNKSR3/UCHL1/GNAQ/PPP1R15B/DMTN/CALM3/CAMK2N1/PRKCD/DUSP7/CASP3/DDIT4/PKIG/RGS14/CTDSP2/PTPN2/CHMP6/ANKLE2/JUN/PLEC/TAF7/PAK2/ADIPOQ/NPM1/SLC8A1/NOG/CIB1/INPP5J/SOCS1/PRKN/NF2/LILRB4/HEXIM1/SPRY4/PPIA/SPRED2/AKT1S1/IPO7/DBNDD2/CEBPA/PRKDC/PTPRC/CDKN1C/LILRB4/PIP4K2B/LILRB4/LILRB4/LRP6/PTEN/CHORDC1 130
GO:0070372 regulation of ERK1 and ERK2 cascade 116/3662 283/15509 4.71676e-11 1.37899e-09 8.29297e-10 CD4/IGF1/CD74/CD44/CASR/FLT4/FGFR2/FGFR3/RPS6KA6/FBLN1/PTPRC/NOX4/ICAM1/ABL1/PDGFB/CCL22/CCL17/NDRG4/PYCARD/CSK/PRKD2/TGFB1/NOD1/ACTA2/CCL2/PDGFRB/IL1A/CCL20/FN1/TEK/PTK2B/INHBA/IL1B/BMP2/CCR7/RRAS/PIN1/KDR/LIF/APOE/EPO/AKAP12/CHI3L1/EPHB2/PTPN22/NOTCH2/PDGFRA/CD36/SPRY2/TLR4/CCL21/FGF2/MAP3K12/ARRB2/SMAD4/TNFRSF11A/APP/EPHA2/CCN1/DUSP10/PDGFC/TPBG/EGFR/NOTCH1/CNKSR3/PRKCA/NODAL/SHC1/ALOX15/ATF3/GPER1/SYK/NDRG2/FRS2/NOD2/LGALS9/RGS14/FGG/FGA/CCL11/CCL19/HRAS/PTPN2/JUN/PTPN11/ADIPOQ/F2R/CSF1R/CIB1/C1QL4/SPRY4/CARD9/HMGB1/SRC/SPRED2/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/PTPRC/CCL5/CCL5/CCL4/CCL18/CCL4/MIF/CCL4/CCL18/CCL18/PTEN 116
GO:0050730 regulation of peptidyl-tyrosine phosphorylation 106/3662 252/15509 5.23325e-11 1.5228e-09 9.15786e-10 CD4/MVP/IGF1/CNTN1/CD74/HGF/CD44/ERBB3/HYAL2/FGFR3/PTPRC/DLG3/PIBF1/NOX4/ABL1/OSM/PDGFB/CD40/ADNP/GATA1/EHD4/SFRP1/IL7/TGFB1/CSF3/UNC119/AREG/HPX/CD81/SH2B3/IFNG/NEDD9/HBEGF/IL12B/IL4/IL5/PPP2CA/HES1/NCL/PDCL3/PTK2B/CD80/FLT3/LIF/EPO/VPS25/LRP4/CD36/IL6/IL21/EGF/ARRB2/APP/PDGFC/EGFR/NCAPG2/IL18/BMP6/KIT/DMTN/ITGB2/SHC1/IL6R/IL24/PRKCD/RICTOR/IL3/CSF2/SYK/ZNF592/NOD2/EFNA1/ALK/PRKCE/CSPG4/LEP/PTPN2/CHMP6/PTPN11/PAK2/ADIPOQ/CSF1R/SOCS1/NF2/LILRB4/SRC/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/GH1/PECAM1/PTPRC/CCL5/CD24/CCL5/LILRB4/MIF/LILRB4/LILRB4 106
GO:0032635 interleukin-6 production 74/3662 156/15509 5.82717e-11 1.67985e-09 1.01023e-09 BTK/TYROBP/CD74/HGF/POU2F2/FOXP3/CYBA/HYAL2/MAVS/P2RX7/XBP1/TLR8/PYCARD/CSK/IL27RA/NOD1/POU2AF1/IFNG/IL17A/WNT5A/IL1A/TNFAIP3/IL1B/FOXJ1/SYT11/PTPN22/CD36/AKIRIN2/IL6/IL10/TLR4/ARRB2/APP/NLRX1/IL6R/MAPKAPK2/CAPN2/TLR3/SYK/NOD2/INPP5D/LGALS9/PTAFR/CEBPB/IL16/LEP/LPL/PTPN11/F2R/LILRB4/CARD9/HMGB1/IL1RAP/TLR7/CD47/MBP/TNF/TNF/HLA-B/HLA-B/TNF/HLA-B/TNF/TNF/HLA-B/TNF/ORM1/TNF/HLA-B/TNF/LILRB4/LILRB4/LILRB4/INPP5D 74
GO:0032675 regulation of interleukin-6 production 74/3662 156/15509 5.82717e-11 1.67985e-09 1.01023e-09 BTK/TYROBP/CD74/HGF/POU2F2/FOXP3/CYBA/HYAL2/MAVS/P2RX7/XBP1/TLR8/PYCARD/CSK/IL27RA/NOD1/POU2AF1/IFNG/IL17A/WNT5A/IL1A/TNFAIP3/IL1B/FOXJ1/SYT11/PTPN22/CD36/AKIRIN2/IL6/IL10/TLR4/ARRB2/APP/NLRX1/IL6R/MAPKAPK2/CAPN2/TLR3/SYK/NOD2/INPP5D/LGALS9/PTAFR/CEBPB/IL16/LEP/LPL/PTPN11/F2R/LILRB4/CARD9/HMGB1/IL1RAP/TLR7/CD47/MBP/TNF/TNF/HLA-B/HLA-B/TNF/HLA-B/TNF/TNF/HLA-B/TNF/ORM1/TNF/HLA-B/TNF/LILRB4/LILRB4/LILRB4/INPP5D 74
GO:0007249 I-kappaB kinase/NF-kappaB signaling 108/3662 259/15509 6.47387e-11 1.85764e-09 1.11715e-09 CASP10/MAP3K14/CD4/BTK/PPP5C/LTF/UFL1/CD74/BIRC3/TRAF1/RHOA/ROCK1/TRAF4/DDX1/MID2/ERC1/FKBP1A/MAVS/ESR1/ABL1/NFKBIA/CD40/VAPA/RIOK3/TLR8/NDFIP2/UBE2I/PYCARD/EEF1D/NOD1/HSPB1/TRIM14/WNT5A/IL1A/STAT1/HDAC1/ASH1L/FASLG/TNFAIP3/TNFRSF10B/TRIM25/TNFSF10/IL1B/RBCK1/CCR7/NR1D1/IRF3/AJUBA/EDA2R/TRAF3/NDFIP1/CC2D1A/TRIM5/TRIM22/CD36/EDNRB/TANK/TLR4/CCL21/PPM1B/PLK2/GJA1/TAB3/FAIM/NLRX1/SHISA5/TLR3/BTRC/NOD2/TRIM68/FADD/NKIRAS2/CX3CR1/RHOH/TNIP2/LGALS9/PRKCE/TRIM8/LURAP1/CCL19/RELA/TMEM9B/ADIPOQ/F2R/IRAK1/PRKN/ROR1/LILRB4/CARD9/TLR7/MIB2/NKIRAS1/TNF/TRIM13/TNF/CHUK/CPNE1/TNF/TNF/TNF/TNF/TNF/TNF/IKBKG/LILRB4/LILRB4/LILRB4/SQSTM1 108
GO:0071706 tumor necrosis factor superfamily cytokine production 78/3662 168/15509 6.66898e-11 1.89607e-09 1.14026e-09 BTK/TYROBP/LTF/IGF1/FOXP3/CYBA/ARG2/PTPRC/MAVS/ACP5/PYCARD/LILRB1/IL27RA/CD33/NOD1/HSPB1/IFNG/IL17A/IL12B/IL4/CD86/WNT5A/IL1A/TNFAIP3/CLU/TNFRSF8/ZFP36/AKAP12/RARA/SYT11/EPHB2/PTPN22/CD36/IL6/IL10/TLR4/THBS1/ARRB2/APP/PIK3R1/MAPKAPK2/PF4/TLR3/SYK/CYBB/NOD2/FADD/CX3CR1/LGALS9/PTAFR/CD14/CCL19/LEP/LPL/PTPN11/ADIPOQ/LILRB4/CARD9/HMGB1/CD47/UBE2J1/HLA-E/HLA-E/HLA-E/HLA-E/ORM1/HLA-E/HLA-E/HLA-E/PTPRC/LILRB1/LILRB4/LILRB1/MIF/LILRB1/LILRB1/LILRB4/LILRB4 78
GO:1903555 regulation of tumor necrosis factor superfamily cytokine production 78/3662 168/15509 6.66898e-11 1.89607e-09 1.14026e-09 BTK/TYROBP/LTF/IGF1/FOXP3/CYBA/ARG2/PTPRC/MAVS/ACP5/PYCARD/LILRB1/IL27RA/CD33/NOD1/HSPB1/IFNG/IL17A/IL12B/IL4/CD86/WNT5A/IL1A/TNFAIP3/CLU/TNFRSF8/ZFP36/AKAP12/RARA/SYT11/EPHB2/PTPN22/CD36/IL6/IL10/TLR4/THBS1/ARRB2/APP/PIK3R1/MAPKAPK2/PF4/TLR3/SYK/CYBB/NOD2/FADD/CX3CR1/LGALS9/PTAFR/CD14/CCL19/LEP/LPL/PTPN11/ADIPOQ/LILRB4/CARD9/HMGB1/CD47/UBE2J1/HLA-E/HLA-E/HLA-E/HLA-E/ORM1/HLA-E/HLA-E/HLA-E/PTPRC/LILRB1/LILRB4/LILRB1/MIF/LILRB1/LILRB1/LILRB4/LILRB4 78
GO:0016032 viral process 144/3662 375/15509 6.98114e-11 1.97576e-09 1.18819e-09 ST3GAL1/CD4/PTBP1/LTF/CD74/YTHDC2/EIF2AK2/HYAL2/ST6GAL1/MID2/GSK3B/ATG16L1/CHMP5/MAVS/CCNK/ICAM1/HSP90AB1/SMARCB1/CHMP4B/VAPA/KPNA3/N4BP1/PARD6A/MON1B/SLC1A5/USF2/GSK3A/EIF3B/TRIM14/EIF3A/CCL2/EFNB3/HSPA8/DDX6/CD81/HCFC2/AICDA/CD86/SPCS1/STAT1/HDAC1/NR5A2/VAMP8/TARDBP/TRIM25/CD80/CXCR4/STAU1/NUP153/DEK/PRMT1/ZFP36/NECTIN2/APOE/CHMP1A/TOP2A/TRIM5/TRIM22/ARL8B/SRPK2/MDFIC/ST6GALNAC4/ITGAV/SLC7A1/TARBP2/FURIN/EPHA2/EGFR/GSN/NOTCH1/NCAM1/HMGA2/ITGB1/BICD1/NMT2/EEF1A1/ST3GAL2/CTBP1/CCR5/GFI1/VCP/MBL2/PSMC3/ANPEP/TRIM68/SLC3A2/ATG16L2/LGALS9/CXCL8/GYPA/PDCD6IP/CDK1/TRIM8/BCL2L1/PAIP1/BSG/HCFC1/CFL1/DAG1/LIG4/LARP7/PDE12/CTBP2/BANF1/CHMP6/TMEM39A/JUN/CD28/CIITA/CSF1R/ST6GALNAC3/PRKN/SLC52A2/IFITM1/HEXIM1/PLSCR1/HMGB1/PPIA/CD55/IGF2R/PCBP2/DPP4/WWP2/CR1/TNF/TRIM13/TNF/ZBED1/TNF/TNF/TNF/TNF/TNF/TNF/TRIM26/TMEM250/ITGB3/CCL5/CCL5/CCL4/CCL4/SMARCB1/CCL4/ITCH 144
GO:0002695 negative regulation of leukocyte activation 87/3662 195/15509 7.40447e-11 2.08604e-09 1.25451e-09 BTK/HFE/TYROBP/CD74/RUNX3/HMGB3/GRN/PARP3/FOXP3/SPI1/CBFB/FCGR2B/TBX21/IL4R/ARG2/PTPRC/PIBF1/CTSG/SMAD7/SFRP1/LILRB1/JAK3/MDK/IL4/BCL6/CD86/ID2/TNFAIP3/ARG1/CD80/INHBA/PKN1/NR1D1/TWSG1/FOXJ1/NDFIP1/SYT11/SFTPD/PTPN22/IL2RA/HLX/IL10/TNFRSF21/MERTK/RUNX1/CTLA4/CASP3/SHH/GPER1/PRDX2/INPP5D/LGALS9/CEBPB/GLMN/RAG2/PTPN2/MICA/SOCS1/LILRB4/CNR2/HMGB1/PDCD1LG2/NRARP/CR1/HLA-G/HLA-G/HLA-G/MICA/MICA/HLA-G/MICA/HLA-G/HLA-G/HLA-G/TNFRSF13B/PTPRC/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 87
GO:0009991 response to extracellular stimulus 171/3662 466/15509 8.56915e-11 2.40324e-09 1.44527e-09 MPO/PON1/HFE/SNAI2/CPS1/GLRX2/RRAGD/FAS/CASR/CLEC16A/HSPA5/CYBA/EIF2AK2/F7/KDM4A/SIRT2/NUCB2/ASNS/MBD3/PTPRC/OXCT1/SEH1L/BAX/P2RX7/GCN1/COMT/SH3GLB1/XBP1/PCK2/ADNP/BMP7/NPRL3/SFRP1/TLE5/HAMP/USF2/MAPK8/RPS6KB1/RNF167/HSPA8/CCND1/FOLR1/CYP27B1/VDR/PPARD/MAPK14/IL1A/ITGA4/STAT1/IGFBP2/ELAPOR1/SLC2A1/NENF/ARG1/FOXO3/SPP1/DNMT3A/TRIM25/CAT/TRIM24/SIRT5/CDKN1A/RUNX2/MAX/BECN1/ATG14/ZFP36/ALDH1A2/CD68/APOE/EPO/GDF15/ASS1/SESN2/RARA/PRKAA1/MYBBP1A/HNRNPA1/GLUL/TTC5/SORL1/CYP1B1/GABARAPL1/BNIP2/IGF1R/BBS4/CYP1A1/MEAK7/TNFRSF11A/PMAIP1/SOD1/ENSA/PKLR/OGT/ALAD/ZEB1/SESN3/FOXO1/NR4A2/KLF10/WIPI2/STC1/ARHGAP35/BRSK1/WNT4/OMA1/VCAM1/ATF3/INHBB/TGFBR2/ALB/RICTOR/TNFRSF11B/CYBB/AQP3/ZFYVE1/SLC27A4/NOD2/MN1/ADRB2/FOS/MGMT/PPM1D/EIF2AK3/KAT5/BRSK2/LEP/DDIT3/LPL/FOSL1/A2M/TYMS/PLEC/RMI1/DCTPP1/SSTR2/NQO1/ADIPOQ/SLC8A1/CNTN2/FOXO4/GAS2L1/PRR5/AKR1C3/TRPV1/SRC/KANK2/MAP3K5/ATG7/NTRK1/F5/MTOR/TNF/TNF/SIPA1/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/ADSL/GH1/PTPRC/PKLR/LOC102724560 171
GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent 16/3662 16/15509 9.10464e-11 2.54192e-09 1.52866e-09 TAP2/TAP2/TAP2/HLA-A/HLA-A/TAP2/HLA-A/HLA-A/TAP2/HLA-A/TAP2/HLA-A/HLA-A/TAP2/HLA-A/TAP2 16
GO:0050673 epithelial cell proliferation 153/3662 406/15509 9.14858e-11 2.54273e-09 1.52915e-09 BAD/WNT16/BTK/IGF1/SNAI2/HGF/RUNX3/BAK1/GRN/FLT4/CYBA/RASGRF1/CDH3/NGFR/TIE1/FGFR2/CDC42/TP63/RAP1GAP/SIRT6/FGFR1/PGR/BAX/APOH/ESR1/XBP1/PDGFB/FERMT1/PPP1R16B/FLT1/EYA1/SFRP1/PRKD2/TGFB1/PTN/HOXA5/TGFBR1/GATA3/CXCL12/BMPR1A/CCL2/AREG/CCND1/MDK/VDR/PPARD/IL12B/WNT5A/HES1/ITGA4/STAT1/PDCL3/ID2/KDM5B/IRF6/NRP2/TNFAIP3/ARG1/KLF9/NR4A3/PGF/TEK/TRIM24/NR4A1/RUNX2/BMP2/ID1/NR1D1/STAT5A/BCL11B/ZFP36/KDR/ALDH1A2/BCL2L2/CDKN1C/APOE/LAMA5/MEN1/LOXL2/NOTCH2/GLUL/LAMC1/EDNRB/IL6/HLX/IL10/CCN3/THBS1/FGF2/EGF/BRCA2/RB1/EPHA2/ARNT/DUSP10/EGFR/IGFBP3/NOTCH1/ZEB1/TCF7L2/VEGFC/BMP6/PRKCA/NODAL/MMP14/KIT/EMC10/PYGO2/AIMP1/AGGF1/SHH/HTRA1/BTRC/FRS2/NOD2/RBPJ/BCL2L1/SCG2/CCL11/CEBPB/CYP7B1/EGFL7/LEP/HRAS/JUN/ERN1/NKX2-5/NOG/ZNF703/ZFP36L1/HMGB1/NRARP/TNF/TNF/ZNF580/NRAS/TNF/TNF/TNF/TNF/TNF/TNF/NME1/NEAT1/PDCD6/PRKDC/ITGB3/B2M/CDKN1C/AKT3/UHRF1/PTEN/TINF2 153
GO:0002710 negative regulation of T cell mediated immunity 28/3662 38/15509 9.40957e-11 2.60359e-09 1.56576e-09 HFE/FOXP3/FCGR2B/TBX21/PTPRC/SMAD7/LILRB1/AHR/PPP3CB/ARG1/NOD2/LILRB4/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/PTPRC/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 28
GO:2000351 regulation of endothelial cell apoptotic process 39/3662 63/15509 9.618e-11 2.64944e-09 1.59333e-09 ICAM1/ABL1/CD40/CD40LG/SERPINE1/GATA3/CCL2/IL4/ITGA4/CD160/FASLG/TNFAIP3/FOXO3/TEK/KDR/THBS1/TERT/GPER1/TNIP2/FGG/FGA/SCG2/AKR1C3/TNF/HLA-G/TNF/HLA-G/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 39
GO:0022408 negative regulation of cell-cell adhesion 86/3662 193/15509 1.02884e-10 2.82157e-09 1.69684e-09 CD9/HFE/CD74/RUNX3/CDH1/FOXP3/SPI1/CBFB/FCGR2B/TBX21/IL4R/ARG2/ABL1/CTSG/SMAD7/LILRB1/TGFB1/JAK3/AKNA/CXCL12/MDK/SH2B3/IL4/BCL6/CD86/ARG1/CD80/BMP2/PODXL/TWSG1/FOXJ1/ASS1/NDFIP1/SFTPD/PTPN22/IL2RA/SERPINE2/HLX/IL10/IL1RN/CCL21/RDX/ADAMTS18/TNFRSF21/NOTCH1/BMP6/RUNX1/CTLA4/PRKCD/CASP3/SHH/PRDX2/LGALS9/PTK2/FGG/CEBPB/GLMN/RAG2/PTPN2/ADIPOQ/ZNF703/SOCS1/NF2/LILRB4/HMGB1/PDCD1LG2/MBP/NRARP/CR1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/PTEN/ITCH 86
GO:1904019 epithelial cell apoptotic process 64/3662 129/15509 1.05917e-10 2.89196e-09 1.73917e-09 BAD/E2F2/BAX/ICAM1/ESR1/ABL1/CD40/CD40LG/PIK3CG/SERPINE1/SFRP4/GATA3/CCL2/MDK/KRT18/IL4/ITGA4/CD160/FASLG/TNFAIP3/FOXO3/DNMT3A/TEK/ZFP36/KDR/PRKAA1/IL6/IL10/THBS1/RB1/IGF1R/ARRB2/GSN/TCF7L2/CAST/TGFBR2/CASP3/TERT/GPER1/TNIP2/BCL2L1/FGG/FGA/SCG2/NKX2-5/ZFP36L1/AKR1C3/MAP3K5/TNF/HLA-G/TNF/HLA-G/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 64
GO:0002922 positive regulation of humoral immune response 25/3662 32/15509 1.12459e-10 3.05711e-09 1.83849e-09 FCGR2B/PTPRC/FCER2/HPX/IL17A/IL1B/C3/CCR7/NOD2/ZP3/CR1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/PTPRC 25
GO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling 98/3662 230/15509 1.17502e-10 3.18024e-09 1.91254e-09 CASP10/MAP3K14/CD4/PPP5C/LTF/UFL1/CD74/BIRC3/TRAF1/RHOA/TRAF4/DDX1/MID2/FKBP1A/MAVS/ESR1/ABL1/CD40/VAPA/RIOK3/NDFIP2/UBE2I/PYCARD/EEF1D/NOD1/HSPB1/TRIM14/WNT5A/IL1A/STAT1/HDAC1/ASH1L/FASLG/TNFAIP3/TNFRSF10B/TRIM25/TNFSF10/IL1B/RBCK1/CCR7/NR1D1/IRF3/AJUBA/EDA2R/TRAF3/NDFIP1/CC2D1A/TRIM5/TRIM22/CD36/TANK/TLR4/CCL21/PPM1B/PLK2/GJA1/TAB3/NLRX1/SHISA5/TLR3/BTRC/NOD2/TRIM68/FADD/NKIRAS2/RHOH/TNIP2/LGALS9/PRKCE/TRIM8/LURAP1/CCL19/RELA/TMEM9B/ADIPOQ/F2R/IRAK1/PRKN/ROR1/LILRB4/CARD9/MIB2/TNF/TRIM13/TNF/CHUK/CPNE1/TNF/TNF/TNF/TNF/TNF/TNF/IKBKG/LILRB4/LILRB4/LILRB4/SQSTM1 98
GO:0048732 gland development 151/3662 401/15509 1.29666e-10 3.49422e-09 2.10136e-09 HOXA11/SNAI2/HGF/CPS1/CDH1/NTN1/FGFR2/PITX1/CSNK2A2/TP63/GLI2/RAP1GAP/HOXA9/PGR/ZMPSTE24/BAX/MMP2/ESR1/ABL1/SMARCB1/XBP1/ACO2/PCK2/BMP7/LAMA1/RPGRIP1L/SFRP1/TGFB1/HAMP/USF2/PTN/MET/HOXA5/EZH2/TGFBR1/GATA3/BMPR1A/WNT3/AREG/CCND1/CCKBR/MDK/VDR/SLC29A1/NPHP3/WNT5A/HES1/ID2/ASH1L/KDM5B/IRF6/TNFAIP3/ARG1/PKD2/CRHR1/BMP2/THRA/STAT5A/ELK1/BCL11B/HOXD3/HOXD9/TWSG1/ALDH1A2/CDO1/LAMA5/ASS1/RARA/NOTCH2/PDGFRA/HNF1A/SERPINE2/IL6/NKX2-1/HLX/IL10/CYP19A1/CYP1B1/FGF2/EGF/BRCA2/CYP1A1/ARMC5/SMAD4/TNFRSF11A/SOD1/EPHA2/EGFR/MSN/NOTCH1/ARID5B/BCL2L11/NODAL/ARHGAP35/WNT4/FRZB/INHBB/PYGO2/TGFBR2/PITX2/SHH/BTRC/FRS2/RAG1/PRDX2/FADD/RBPJ/MGMT/CCL11/CEBPB/CYP7B1/RARG/RELA/DAG1/STAT5B/SMAD2/ZDHHC21/TYMS/JUN/OXTR/PLAG1/CACNB4/CSF1R/EPHB3/NKX2-5/NOG/ZNF703/CSF1/POU3F2/PBX1/WNT7B/IGF2R/SRC/PHF2/TGM2/MAFB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NME1/CEBPA/HOXA10/SMARCB1/WNT3/WNT3/PTEN 151
GO:0002719 negative regulation of cytokine production involved in immune response 31/3662 45/15509 1.52269e-10 4.08555e-09 2.45698e-09 HFE/FOXP3/TBX21/SMAD7/ACP5/LILRB1/TGFB1/JAK3/BCL6/ARG1/IL10/CD96/NLRX1/NOD2/PRG2/LILRB4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 31
GO:1904035 regulation of epithelial cell apoptotic process 55/3662 105/15509 1.54312e-10 4.12253e-09 2.47922e-09 BAD/BAX/ICAM1/ESR1/ABL1/CD40/CD40LG/SERPINE1/SFRP4/GATA3/CCL2/MDK/IL4/ITGA4/CD160/FASLG/TNFAIP3/FOXO3/TEK/ZFP36/KDR/PRKAA1/IL6/THBS1/RB1/IGF1R/ARRB2/GSN/TCF7L2/CAST/TERT/GPER1/TNIP2/FGG/FGA/SCG2/NKX2-5/ZFP36L1/AKR1C3/TNF/HLA-G/TNF/HLA-G/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 55
GO:0061082 myeloid leukocyte cytokine production 37/3662 59/15509 1.69348e-10 4.48554e-09 2.69753e-09 CD74/DDX1/MAVS/P2RX7/ACP5/PYCARD/LILRB1/TGFB1/NOD1/BCL6/WNT5A/NR4A3/CD36/TLR4/KIT/NLRX1/MAPKAPK2/TLR3/SYK/NOD2/PRG2/CARD9/TLR7/UBE2J1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/HLA-G/LILRB1/MIF/LILRB1/LILRB1 37
GO:0097028 dendritic cell differentiation 37/3662 59/15509 1.69348e-10 4.48554e-09 2.69753e-09 SPI1/FCGR2B/DHRS2/GATA1/LILRB1/IL4/FLT3/CCR7/NOTCH2/IRF4/IRF8/TGFBR2/CSF2/RBPJ/LGALS9/CEBPB/CCL19/HMGB1/PRTN3/HLA-G/HLA-B/HLA-G/HLA-B/HLA-B/HLA-B/HLA-G/HLA-B/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/HLA-G/LILRB1/LILRB1/PRTN3/LILRB1 37
GO:0014066 regulation of phosphatidylinositol 3-kinase signaling 56/3662 108/15509 1.76224e-10 4.64782e-09 2.79511e-09 WNT16/DCN/IGF1/HGF/ERBB3/FGFR1/OSM/PIK3IP1/PDGFB/PPP1R16B/FLT1/TSC2/UNC5B/CSF3/PPARD/PDGFRB/FN1/TEK/CAT/FLT3/BECN1/KDR/PDGFRA/SERPINE2/FGF2/EGF/IGF1R/PDGFC/EGFR/NTRK2/IL18/KIT/GPER1/PTK2/SEMA3E/SELP/LEP/CD28/F2/F2R/ROR1/PRR5/SRC/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/CCL5/CCL5/PTEN 56
GO:0032757 positive regulation of interleukin-8 production 39/3662 64/15509 1.90211e-10 4.99545e-09 3.00418e-09 CD74/HYAL2/MAVS/TLR8/PYCARD/PRKD2/NOD1/SERPINE1/WNT5A/PARK7/CD244/IL1B/CHI3L1/IL6/TLR4/TLR3/SYK/NOD2/FADD/LGALS9/CD14/RELA/LEP/DDIT3/ADIPOQ/F2R/HMGB1/TLR7/ELANE/TNF/TNF/ZNF580/TNF/TNF/TNF/TNF/TNF/TNF/ELANE 39
GO:0050679 positive regulation of epithelial cell proliferation 88/3662 201/15509 1.92673e-10 5.03876e-09 3.03022e-09 BAD/BTK/IGF1/GRN/FLT4/CYBA/CDH3/FGFR2/CDC42/TP63/SIRT6/FGFR1/XBP1/PDGFB/PPP1R16B/EYA1/SFRP1/PRKD2/PTN/TGFBR1/CXCL12/BMPR1A/AREG/CCND1/MDK/WNT5A/ITGA4/PDCL3/KDM5B/NRP2/TNFAIP3/ARG1/NR4A3/PGF/TEK/NR4A1/RUNX2/BMP2/ID1/STAT5A/KDR/NOTCH2/GLUL/LAMC1/HLX/IL10/FGF2/EGF/ARNT/EGFR/NOTCH1/TCF7L2/VEGFC/BMP6/PRKCA/NODAL/EMC10/AGGF1/SHH/HTRA1/NOD2/RBPJ/SCG2/CCL11/CYP7B1/EGFL7/HRAS/JUN/NKX2-5/NOG/ZNF703/HMGB1/NRARP/TNF/TNF/ZNF580/NRAS/TNF/TNF/TNF/TNF/TNF/TNF/NME1/NEAT1/PDCD6/ITGB3/AKT3 88
GO:0072577 endothelial cell apoptotic process 41/3662 69/15509 1.99469e-10 5.19457e-09 3.12392e-09 ICAM1/ABL1/CD40/CD40LG/SERPINE1/GATA3/CCL2/IL4/ITGA4/CD160/FASLG/TNFAIP3/FOXO3/TEK/KDR/IL10/THBS1/TERT/GPER1/TNIP2/FGG/FGA/SCG2/AKR1C3/MAP3K5/TNF/HLA-G/TNF/HLA-G/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 41
GO:0002009 morphogenesis of an epithelium 176/3662 488/15509 2.24204e-10 5.81429e-09 3.49661e-09 WNT16/HOXA11/PAFAH1B1/SNAI2/HGF/CD44/CASR/LAMA3/NGFR/NTN1/TIE1/FGFR2/RHOA/CDC42/WDR1/PRKACA/TP63/GLI2/ACTB/GPC4/SIRT6/TULP3/LRP2/PGR/DLG3/RAB10/TMED2/MMP2/KDM2B/ESR1/HECTD1/ABL1/CECR2/MTHFD1/BMP7/FERMT1/LAMA1/NDRG4/TSC2/RPGRIP1L/EYA1/SFRP1/PRKD2/TGFB1/TMEM59L/MET/HOXA5/ENG/DVL1/GATA3/DKK1/AREG/FOLR1/MDK/WNT5B/VDR/HBEGF/NPHP3/WNT5A/HES1/STAT1/KDM5B/PKD2/GNA13/MTHFD1L/GORAB/CXCR4/SOX4/BMP2/FLRT3/KDR/LIF/PODXL/ALDH1A2/AJUBA/COL5A1/LAMA5/RARA/GRSF1/KRAS/NOTCH2/AHI1/SPRY2/CCM2/NKX2-1/IL10/TFAP2A/FGF2/EGF/BBS4/ITGAX/GREB1L/SMAD4/EPHA2/CCN1/CELSR2/RHOB/SLIT2/ADAMTS16/KLHL3/EGFR/MSN/NOTCH1/ITGB1/VEGFC/FREM2/GJA1/NODAL/MMP14/SKI/ARHGAP35/BRSK1/DVL3/WNT4/VANGL2/RBM15/FRZB/TGFBR2/CASP3/FOXQ1/SHH/ARHGAP12/TTC8/BTRC/FRS2/RBPJ/SEMA4C/ARL13B/SEMA3E/CCL11/CYP7B1/RARG/DAG1/HOXB2/BRSK2/GLMN/GRB2/CTNNBIP1/CXCR2/SETD2/RGMA/CSF1R/NKX2-5/NOG/CSF1/ROR1/PBX1/MAGI2/WNT7B/MRTFA/SRC/NRARP/MTOR/TGM2/BRD2/FKBPL/CSNK2B/TNF/TCTN1/TNF/BRD2/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/BRD2/TNF/CSNK2B/BRD2/BRD2/PTEN/PRKACA 176
GO:0050678 regulation of epithelial cell proliferation 134/3662 348/15509 2.58358e-10 6.67209e-09 4.01248e-09 BAD/BTK/IGF1/SNAI2/RUNX3/GRN/FLT4/CYBA/CDH3/NGFR/TIE1/FGFR2/CDC42/TP63/RAP1GAP/SIRT6/FGFR1/PGR/BAX/APOH/XBP1/PDGFB/PPP1R16B/FLT1/EYA1/SFRP1/PRKD2/TGFB1/PTN/HOXA5/TGFBR1/GATA3/CXCL12/BMPR1A/CCL2/AREG/CCND1/MDK/VDR/PPARD/IL12B/WNT5A/HES1/ITGA4/STAT1/PDCL3/KDM5B/IRF6/NRP2/TNFAIP3/ARG1/KLF9/NR4A3/PGF/TEK/TRIM24/NR4A1/RUNX2/BMP2/ID1/NR1D1/STAT5A/BCL11B/ZFP36/KDR/ALDH1A2/CDKN1C/APOE/LAMA5/MEN1/NOTCH2/GLUL/LAMC1/EDNRB/HLX/IL10/THBS1/FGF2/EGF/BRCA2/RB1/ARNT/DUSP10/EGFR/NOTCH1/ZEB1/TCF7L2/VEGFC/BMP6/PRKCA/NODAL/EMC10/PYGO2/AIMP1/AGGF1/SHH/HTRA1/FRS2/NOD2/RBPJ/SCG2/CCL11/CYP7B1/EGFL7/LEP/HRAS/JUN/NKX2-5/NOG/ZNF703/ZFP36L1/HMGB1/NRARP/TNF/TNF/ZNF580/NRAS/TNF/TNF/TNF/TNF/TNF/TNF/NME1/NEAT1/PDCD6/PRKDC/ITGB3/B2M/CDKN1C/AKT3/UHRF1/PTEN/TINF2 134
GO:0045445 myoblast differentiation 53/3662 101/15509 3.03707e-10 7.81068e-09 4.6972e-09 IFRD1/IGF1/ARID1B/PITX1/ACTB/MBNL3/SMARCB1/CCL17/TGFB1/SMARCD2/DDX5/PPARD/MAPK14/SDC1/EPAS1/BCL9/ARID1A/SOX4/SOX15/FLOT2/BTG1/RB1/IGFBP3/NOTCH1/TCF7L2/ITGB1/IL18/MBNL1/XKR8/MAML1/RANBP3L/SHH/HIF1AN/BRD7/RBPJ/KAT5/DDIT3/PLEC/PLCB1/ZFP36L1/BCL9L/ARID2/MAP3K5/TNF/TNF/NRAS/TNF/TNF/TNF/TNF/TNF/TNF/SMARCB1 53
GO:0060907 positive regulation of macrophage cytokine production 25/3662 33/15509 3.59414e-10 9.20515e-09 5.53581e-09 CD74/P2RX7/PYCARD/LILRB1/NOD1/WNT5A/CD36/TLR4/MAPKAPK2/TLR3/NOD2/CARD9/TLR7/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1 25
GO:0045589 regulation of regulatory T cell differentiation 31/3662 46/15509 3.61223e-10 9.21342e-09 5.54079e-09 FOXP3/MDK/IFNG/BCL6/FOXO3/DUSP10/IL2RG/CTLA4/LGALS9/KAT5/CD28/KLHL25/SOCS1/LILRB4/CR1/HLA-G/HLA-DRA/HLA-G/HLA-DRA/HLA-DRA/HLA-G/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4 31
GO:0002544 chronic inflammatory response 24/3662 31/15509 3.75111e-10 9.52844e-09 5.73024e-09 FOXP3/IL4/TNFAIP3/IL10/THBS1/CYP19A1/CXCL13/VCAM1/CCL11/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/CCL5/CCL5 24
GO:0006959 humoral immune response 102/3662 247/15509 4.20731e-10 1.06436e-08 6.40089e-09 LTF/SLC11A1/POU2F2/TFE3/FCGR2B/ST6GAL1/PTPRC/CD59/LYZ/CTSG/IL7/FCER2/GPI/GATA3/C1QBP/CCL2/HPX/CD81/POU2AF1/IFNG/IL17A/GNLY/CFHR3/CLU/SEMG1/H2BC11/IL1B/C3/CCR7/FOXJ1/SFTPD/NOTCH2/IL6/TNFRSF21/NOTCH1/CXCL13/MS4A1/PF4/MBL2/NOD2/RBPJ/CXCL8/FGA/A2M/CD28/HLA-DQB1/F2/H2BC21/ZP3/CD55/PRTN3/ELANE/IFNA1/HMGN2/RPL39/CR1/TNF/HLA-E/PSMB10/HLA-DQB1/HLA-DQB1/TNF/HLA-E/HLA-A/HLA-A/LTA/TNF/HLA-A/HLA-A/HLA-E/HLA-DQB1/LTA/HLA-A/TNF/TNF/TNF/HLA-A/HLA-E/TNF/HLA-E/LTA/HLA-DQB1/LTA/HLA-A/HLA-DQB1/TNF/HLA-DQB1/HLA-E/HLA-A/HLA-E/LTA/CFB/CFB/CFB/CFB/CFB/PTPRC/H2BC6/H2BC7/ELANE/PRTN3/GPI 102
GO:1901652 response to peptide 165/3662 454/15509 4.27532e-10 1.07717e-08 6.47792e-09 CRY1/IGF1/CPS1/CASR/CYBA/KCNQ1/F7/NGFR/PKM/ROCK1/FCGR2B/ACTN2/OPRK1/GSK3B/RAB10/CHMP5/MMP2/PXN/NUDC/ICAM1/CDC6/XBP1/RANGAP1/APEX1/PCK2/NFKBIA/MMP9/BMP7/TSC2/ABCC1/CSK/PLAT/SLC39A14/KLF1/JAK3/GSK3A/NOD1/CXCL12/RPS6KB1/AREG/MAPK14/CCND3/KAT2B/NCL/ITGA4/STAT1/SRSF4/SLC2A1/TNFAIP3/ARG1/FOXO3/NR4A3/EIF2B2/CRHR1/EGR1/CRY2/CAT/TNFSF10/INHBA/EGR2/NR4A1/LRP1/NCOA5/IL1B/MAX/ID1/STAT5A/IRF5/BCL2L2/CDO1/GDF15/ASS1/SESN2/PRKAA1/LPIN3/EPHB2/MEN1/PTPN22/APC/CD36/EDNRB/IL10/TLR4/SORL1/KHK/CYP1B1/RB1/IGF1R/MEAK7/TNFRSF11A/APP/RAB13/PKLR/PARP1/CCNA2/PIK3R1/OGT/NOTCH1/EIF4EBP2/SESN3/SOGA1/FOXO1/POU4F2/GJA1/BCL2L11/NR4A2/APPL1/ADIPOR1/BTG2/SHC1/JAK1/SCNN1D/VCAM1/INHBB/PRKCD/GPER1/CDK5/CYBB/ZNF592/SLC27A4/NOD2/AHCYL1/ADRB2/PTK2/FOS/SLC25A33/KLF11/BSG/RELA/ESRRA/DAG1/STAT5B/LEP/PTPN2/LPL/GRB2/ERFE/PTPN11/OXTR/ADIPOQ/PLCB1/FOXO4/SOCS1/ZFP36L1/CARD9/TRPV1/SRC/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/PRKDC/ITGB3/GH1/PKLR/PIP4K2B/NEFL/ABCC1/LRP6 165
GO:0060284 regulation of cell development 174/3662 485/15509 4.55042e-10 1.14184e-08 6.86683e-09 BAD/KDM1A/HOXA11/TMEM98/IFRD1/PAFAH1B1/TYROBP/LTF/UFL1/IGF1/TNFRSF1B/GRN/CDH1/NTN1/KDM4A/ROCK1/SIRT2/CDC42/PLXNA2/FBLN1/PCM1/TP73/XRCC5/LRP2/GSK3B/ADD1/ABL1/ADNP/BMP7/SMAD7/OLFM4/LILRB1/TGFB1/GSK3A/PTN/EZH2/CXCL12/BMPR1A/WNT3/C1QBP/EFNB3/MDK/CORO1C/IFNG/NEDD9/IL5/DBN1/WNT5A/HES1/IL1A/FN1/ID2/HDAC1/MPL/SPP1/CXCR4/RECK/EGR2/OBSL1/IL1B/NKX2-2/BMP2/ID1/NR1D1/YWHAH/LIF/PER2/EPHB2/KRAS/BHLHE40/NOTCH2/NGF/LRP4/SERPINE2/EDNRB/IL6/DBNL/KIAA0319/SORL1/ACTR2/FGF2/RB1/SMAD4/CRABP2/DUSP10/HES6/CTDSP1/SLIT2/NTRK2/NOTCH1/ITGB1/VEGFC/POU4F2/POU4F1/NODAL/KIT/DPYSL5/SKI/FAIM/DMTN/TBC1D24/DISC1/FRZB/HEYL/MELTF/SLC9B2/SHH/GPER1/CDK5/CX3CR1/SEMA4C/RGS14/LIMS1/SEMA3E/LPAR3/MAP6/FGG/FGA/CCL11/PDE3A/DAG1/LIG4/ZDHHC21/BDNF/RCC2/CALR/CDH4/F2/ADIPOQ/PLAG1/PLCB1/ANXA2/RFLNB/NOG/SS18L1/CIB1/NF2/DCC/SPRY4/MME/TRPV1/SYNGAP1/MBP/MTOR/GPRASP3/TGM2/GDI1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/TWF2/SHANK3/PRKDC/CUX1/ITGB3/B2M/LILRB1/LILRB1/LILRB1/NEFL/WNT3/WNT3/LILRB1/PTEN 174
GO:0034101 erythrocyte homeostasis 62/3662 127/15509 4.78794e-10 1.1966e-08 7.19613e-09 SLC4A1/KMT2E/UFL1/ALAS1/KCNQ1/HIPK2/SPI1/ACIN1/GATA1/ERCC2/GPI/KLF1/JAK3/HOXA5/GATA3/HOXB6/SLC11A2/SH2B3/MAPK14/RHAG/HSPA9/SMAD5/BCL6/STAT1/ID2/EPAS1/PRDX1/MYB/FOXO3/PTBP3/INHBA/THRA/PRMT1/ZFP36/EPO/ABCB10/IREB2/RB1/ARNT/DYRK3/NCAPG2/KIT/ALAS2/DMTN/TAL1/BAP1/CASP3/SFXN1/EPB42/INPP5D/AHSP/STAT5B/PTPN2/RPS17/ZFP36L1/CDIN1/L3MBTL3/MAFB/PRKDC/B2M/INPP5D/GPI 62
GO:0050727 regulation of inflammatory response 137/3662 361/15509 5.12881e-10 1.27664e-08 7.6775e-09 SELE/BTK/UFL1/IGF1/HGF/BIRC3/TNFRSF1B/GRN/FOXP3/KARS1/HYAL2/VPS35/FCGR2B/MKRN2/PTPRC/ESR1/OSM/PSMA6/NFKBIA/MMP9/HCK/ACP5/SETD6/ABCC1/MEFV/PYCARD/HAMP/PIK3CG/SERPINE1/AKNA/GATA3/CTSC/MDK/CD81/MVK/IFNG/PPARD/MAPK14/IL12B/IL4/BCL6/WNT5A/SNX4/PARK7/ASH1L/TNFAIP3/VAMP8/AREL1/TEK/IL1B/C3/CCR7/NR1D1/IRF3/ZFP36/APOE/NDFIP1/SYT11/IL2RA/DAGLA/NT5E/EDNRB/IL6/IL10/TLR4/CCN3/CYP19A1/IL21/RB1/FURIN/TNFRSF11A/SOD1/APP/DUSP10/PLK2/IL18/NDUFC2/PSMB4/NLRX1/ALOX15/CAMK2N1/BAP1/PRKCD/RICTOR/TLR3/GPER1/SYK/NOD2/GPX4/CEBPB/IL16/RELA/STAT5B/PTPN2/LPL/CD28/LACC1/ADIPOQ/ZP3/CNR2/TLR7/CD47/SRC/SHPK/ELANE/TNF/HLA-E/TMSB4X/TNF/HLA-E/LTA/TNF/HLA-E/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/LTA/TNF/HLA-E/HLA-E/LTA/NEAT1/CEBPA/NAIP/PTPRC/CCL5/CCL5/NAIP/ELANE/ABCC1/NAIP/GGT1 137
GO:0034248 regulation of cellular amide metabolic process 149/3662 401/15509 5.17008e-10 1.28177e-08 7.70831e-09 UPF1/IGF1/EIF2AK2/PUM2/EIF4B/ELAVL1/PKM/RHOA/ROCK1/PDK3/ELP1/PICALM/MLH1/MKNK1/DDX1/BZW1/TUT7/TMED2/PPP1R15A/MAPKAPK5/GCN1/AARS1/AGO1/CIRBP/MKNK2/GZMB/PCIF1/GSK3A/MTPN/HSPB1/EIF3B/EIF4H/EXOSC3/LARP4B/CASC3/RPS6KB1/C1QBP/DPH1/EIF4G2/DDX6/IFNG/XRN1/EIF1B/NCL/PASK/DPH5/FOXO3/EIF2B2/MTRF1/PAIP2/SERP1/CLU/PTK2B/TARDBP/ORMDL2/SOX4/CNOT1/TRAP1/PIN1/ZFP36/APOE/SESN2/RARA/PER2/PRKAA1/RTN3/ELP2/NIBAN1/EIF4E2/IL6/BZW2/IREB2/NCBP1/SORL1/THBS1/CYP1B1/LARP1B/TARBP2/RTN1/TOB1/EIF4A3/GRB7/APP/CCN1/POLR2D/CNOT9/EIF3H/NTRK2/EIF4EBP2/MTG1/SLC2A13/CDC123/GUF1/ZFP36L2/RMND1/USP16/EIF4A2/CNOT11/PPP1R15B/BTG2/ZNF385A/RPL26/PRKCD/CASP3/RPUSD4/NOD2/EFNA1/PTAFR/ELP5/PA2G4/PGAM1/ENC1/ORMDL3/EIF2AK3/PAIP1/DCP2/RELA/EIF1/PDE12/TYMS/SHMT1/CD28/CALR/TRNAU1AP/NPM1/KLHL25/EIF3C/ZFP36L1/YTHDF3/SECISBP2/DAPK1/MTOR/SELENOT/GIGYF2/TNF/SARNP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/PRKDC/LSM14A/RBM8A/CCL5/CCL5 149
GO:0002263 cell activation involved in immune response 107/3662 264/15509 5.74075e-10 1.40637e-08 8.45767e-09 ITGAL/TMEM98/ST3GAL1/BTK/TYROBP/SLC11A1/CD74/GRN/GAB2/PARP3/C12orf4/FOXP3/KARS1/SPI1/FCGR2B/TBX21/MLH1/STXBP2/IL4R/PTPRC/LAT2/ICAM1/MSH2/IL12RB1/ABL1/XBP1/CD40/SMAD7/GATA1/CD40LG/PYCARD/NBN/LILRB1/IL27RA/TGFB1/JAK3/PIK3CG/EXOSC3/GATA3/NSD2/MDK/CD81/POU2AF1/IFNG/AICDA/IL12B/IL4/BCL6/CD86/SNX4/MYB/VAMP8/NR4A3/PTK2B/CD80/CD244/SHLD2/LRP1/RAC2/NDFIP1/RARA/NOTCH2/LCP1/IL6/HLX/IL10/STXBP1/TLR4/IRF4/IL21/SLC15A4/IRF8/APP/CPLX2/IL18/KIT/CD1C/ITGB2/IL6R/TNFSF13/SYK/CX3CR1/LGALS9/PTAFR/ITGAM/PRKCE/CCL19/LIG4/RAG2/CD19/CD28/HMGB1/IFNA1/ENTPD7/MTOR/CR1/CD177/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/PTPRC/LILRB1/LILRB1/LILRB1/HLA-DRA/LILRB1 107
GO:0002429 immune response-activating cell surface receptor signaling pathway 107/3662 264/15509 5.74075e-10 1.40637e-08 8.45767e-09 CD38/CD79B/BTK/TYROBP/CD22/BTN3A1/FOXP3/FCGR2B/PTPRC/LAT2/BAX/SPG21/BAG6/ABL1/NFATC2/HCK/CSK/KCNN4/PRKD2/CD79A/GATA3/LPXN/CD81/PDE4D/ZAP70/CD160/NR4A3/EIF2B2/RBCK1/CCR7/NECTIN2/PTPN22/CMTM3/TNFRSF21/CD8A/MS4A1/APPL1/SPPL3/ICOSLG/CTLA4/PRKCD/SYK/MBL2/BTNL9/INPP5D/PTK2/PRKCE/RELA/HRAS/PTPN2/CD19/CD28/HLA-DQB1/PAK2/CACNB4/PDE4B/BTN3A2/LILRB4/PLSCR1/CD47/SRC/CR1/BAG6/HLA-DQB1/HLA-DQB1/MICB/HLA-A/HLA-A/HLA-DPB1/NCR3/HLA-DPB1/HLA-A/HLA-A/MICB/NCR3/HLA-DQB1/HLA-DPB1/HLA-A/MICB/BAG6/HLA-A/HLA-DPB1/BAG6/HLA-DPB1/HLA-DPB1/MICB/HLA-DQB1/MICB/HLA-A/HLA-DQB1/HLA-DQB1/BAG6/BAG6/HLA-A/NCR3/HLA-DPB1/NCR3/NCR3/HLA-DPB1/NCR3/MICB/PTPRC/IKBKG/LILRB4/LILRB4/LILRB4/INPP5D 107
GO:0002757 immune response-activating signal transduction 107/3662 264/15509 5.74075e-10 1.40637e-08 8.45767e-09 CD38/CD79B/BTK/TYROBP/CD22/BTN3A1/FOXP3/FCGR2B/PTPRC/LAT2/BAX/SPG21/BAG6/ABL1/NFATC2/HCK/CSK/KCNN4/PRKD2/CD79A/GATA3/LPXN/CD81/PDE4D/ZAP70/CD160/NR4A3/EIF2B2/RBCK1/CCR7/NECTIN2/PTPN22/CMTM3/TNFRSF21/CD8A/MS4A1/APPL1/SPPL3/ICOSLG/CTLA4/PRKCD/SYK/MBL2/BTNL9/INPP5D/PTK2/PRKCE/RELA/HRAS/PTPN2/CD19/CD28/HLA-DQB1/PAK2/CACNB4/PDE4B/BTN3A2/LILRB4/PLSCR1/CD47/SRC/CR1/BAG6/HLA-DQB1/HLA-DQB1/MICB/HLA-A/HLA-A/HLA-DPB1/NCR3/HLA-DPB1/HLA-A/HLA-A/MICB/NCR3/HLA-DQB1/HLA-DPB1/HLA-A/MICB/BAG6/HLA-A/HLA-DPB1/BAG6/HLA-DPB1/HLA-DPB1/MICB/HLA-DQB1/MICB/HLA-A/HLA-DQB1/HLA-DQB1/BAG6/BAG6/HLA-A/NCR3/HLA-DPB1/NCR3/NCR3/HLA-DPB1/NCR3/MICB/PTPRC/IKBKG/LILRB4/LILRB4/LILRB4/INPP5D 107
GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin 18/3662 20/15509 5.7861e-10 1.4119e-08 8.49091e-09 PTPRC/FCER2/HPX/NOD2/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/PTPRC 18
GO:0051402 neuron apoptotic process 98/3662 236/15509 6.44751e-10 1.56712e-08 9.42441e-09 TYROBP/FAS/GRN/HSPA5/NGFR/HIPK2/ERBB3/MAP2K4/RHOA/ROCK1/TP63/BAX/KDM2B/AARS1/MSH2/HSP90AB1/ABL1/MYBL2/ADNP/IL27RA/GPI/GSK3A/CASP2/GATA3/UNC5B/CCL2/ZPR1/CCND1/MDK/PARK7/FASLG/FOXO3/PTK2B/CNTFR/TMTC4/MAX/KDR/APOE/KRAS/NGF/SRPK2/IL10/STXBP1/TFAP2A/MAP3K12/TMBIM6/RB1/ARRB2/SOD1/APP/PARP1/TNFRSF21/NONO/NTRK2/THRB/POU4F1/BCL2L11/NR4A2/BTG2/CASP3/TERT/FOXQ1/CDK5/NSMF/FADD/CX3CR1/ITGAM/SEMA3E/BCL2L1/CEBPB/LIG4/HRAS/DDIT3/BDNF/CDK5R1/JUN/NQO1/F2R/PRKN/CLN3/FZD9/SYNGAP1/NTRK1/GPRASP3/TNF/AKT1S1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NEFL/NAIP/GPI 98
GO:0031667 response to nutrient levels 159/3662 436/15509 6.69743e-10 1.62151e-08 9.75148e-09 MPO/PON1/HFE/SNAI2/CPS1/RRAGD/FAS/CASR/CLEC16A/HSPA5/CYBA/EIF2AK2/F7/KDM4A/SIRT2/NUCB2/ASNS/MBD3/OXCT1/SEH1L/BAX/GCN1/COMT/SH3GLB1/XBP1/PCK2/BMP7/NPRL3/SFRP1/HAMP/USF2/MAPK8/RPS6KB1/RNF167/HSPA8/CCND1/FOLR1/CYP27B1/VDR/PPARD/MAPK14/IL1A/STAT1/IGFBP2/ELAPOR1/SLC2A1/NENF/ARG1/FOXO3/SPP1/DNMT3A/TRIM25/CAT/TRIM24/SIRT5/CDKN1A/RUNX2/MAX/BECN1/ATG14/ZFP36/ALDH1A2/CD68/APOE/EPO/GDF15/ASS1/SESN2/RARA/PRKAA1/MYBBP1A/HNRNPA1/GLUL/TTC5/SORL1/CYP1B1/GABARAPL1/BNIP2/IGF1R/BBS4/CYP1A1/MEAK7/TNFRSF11A/PMAIP1/SOD1/ENSA/PKLR/OGT/ALAD/ZEB1/SESN3/FOXO1/KLF10/WIPI2/STC1/BRSK1/WNT4/OMA1/VCAM1/ATF3/INHBB/TGFBR2/ALB/RICTOR/TNFRSF11B/CYBB/AQP3/ZFYVE1/SLC27A4/NOD2/MN1/ADRB2/FOS/MGMT/PPM1D/EIF2AK3/KAT5/BRSK2/LEP/DDIT3/LPL/A2M/TYMS/PLEC/RMI1/SSTR2/NQO1/ADIPOQ/SLC8A1/CNTN2/FOXO4/GAS2L1/PRR5/AKR1C3/TRPV1/SRC/KANK2/MAP3K5/ATG7/NTRK1/F5/MTOR/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/ADSL/GH1/PKLR/LOC102724560 159
GO:0046641 positive regulation of alpha-beta T cell proliferation 27/3662 38/15509 7.92718e-10 1.91178e-08 1.14971e-08 PTPRC/CD81/IL12B/ZAP70/PTPN22/IL18/TGFBR2/SYK/LGALS9/CD28/CD55/HLA-E/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-A/HLA-E/PTPRC 27
GO:0002253 activation of immune response 130/3662 340/15509 8.12721e-10 1.95242e-08 1.17415e-08 CD38/CD79B/BTK/TYROBP/CD22/BTN3A1/FOXP3/FCGR2B/XRCC5/PTPRC/CD59/LAT2/BAX/MAVS/SPG21/BAG6/ABL1/NFATC2/HCK/PYCARD/CSK/KCNN4/PRKD2/CD79A/GATA3/C1QBP/LPXN/CD81/PDE4D/ZAP70/CFHR3/CD160/NR4A3/EIF2B2/CLU/IL1B/C3/RBCK1/CCR7/NECTIN2/TRIM5/PTPN22/TLR4/CMTM3/TNFRSF21/NONO/CD8A/MS4A1/APPL1/SPPL3/ICOSLG/CTLA4/PRKCD/SYK/MBL2/BTNL9/NOD2/INPP5D/PTK2/PRKCE/RELA/HRAS/PTPN2/A2M/CD19/CD28/HLA-DQB1/PAK2/CACNB4/PDE4B/BTN3A2/LILRB4/HEXIM1/PLSCR1/HMGB1/CD55/CD47/SRC/CR1/BAG6/HLA-DQB1/HLA-DQB1/MICB/HLA-A/HLA-A/HLA-DPB1/NCR3/HLA-DPB1/HLA-A/HLA-A/MICB/NCR3/HLA-DQB1/HLA-DPB1/HLA-A/MICB/BAG6/HLA-A/HLA-DPB1/BAG6/HLA-DPB1/HLA-DPB1/MICB/HLA-DQB1/MICB/HLA-A/HLA-DQB1/HLA-DQB1/BAG6/BAG6/HLA-A/NCR3/HLA-DPB1/NCR3/NCR3/HLA-DPB1/NCR3/MICB/CFB/CFB/CFB/CFB/CFB/PRKDC/PTPRC/IKBKG/LILRB4/LILRB4/LILRB4/INPP5D 130
GO:0050864 regulation of B cell activation 65/3662 137/15509 8.33574e-10 1.99478e-08 1.19963e-08 BAD/CD38/BTK/TYROBP/CD22/CD74/HMGB3/PARP3/FOXP3/FCGR2B/TBX21/MLH1/PTPRC/MSH2/XBP1/CD40/NFATC2/SFRP1/IL7/IL27RA/TGFB1/AHR/EXOSC3/NSD2/CD81/IL4/IL5/BCL6/ID2/TNFAIP3/SHLD2/INHBA/PKN1/CDKN1A/FOXJ1/NDFIP1/EPHB2/AKIRIN2/IL6/IL10/TLR4/IL21/SLC15A4/TNFRSF21/IL2RG/ZFP36L2/MMP14/TNFRSF13C/TNFSF13/CTLA4/CASP3/SYK/NOD2/TNIP2/INPP5D/STAT5B/CD19/CD28/ZFP36L1/CR1/TNFRSF13B/PTPRC/MIF/INPP5D/PTEN 65
GO:0007346 regulation of mitotic cell cycle 157/3662 431/15509 9.42027e-10 2.24565e-08 1.35049e-08 CDC27/KMT2E/PAFAH1B1/IGF1/FHL1/YTHDC2/ARID1B/SIRT2/ASNS/CDC42/ACTB/TP73/NDC80/ZMPSTE24/ZW10/ANAPC5/BIRC5/ZNF268/PSME1/CDC6/MSH2/ABL1/CDC7/BCL7C/SMARCB1/TTC28/PDGFB/APEX1/BMP7/CDC25B/RBBP8/RAB11A/NBN/ERCC2/CASP2/EZH2/RPS6KB1/SMARCD2/CCL2/CCND1/BCL7A/FBXO5/SMOC2/CCND3/CUL9/CCNG1/RAD50/PPP2CA/PDGFRB/BCL6/HES1/TTL/IL1A/ID2/CDC20/ARID1A/PKD2/TEX14/INHBA/OBSL1/CDKN1A/IL1B/HSPA2/PIN1/PKMYT1/CDKN1C/PSME3/BTG1/CCNB1/CCNH/CDCA8/APC/BORA/IL10/TMEM8B/RDX/NUSAP1/CENPE/EGF/NABP2/BRCA2/RB1/CUL4A/CYP1A1/APP/DTL/INTS3/CTDSP1/PLK2/EGFR/MKI67/SPC25/ZFP36L2/PRKCA/ADAMTS1/XPC/EME1/LSM11/APPL1/CUL4B/BTG2/PRMT2/BRSK1/MRNIP/DBF4B/RPL26/TAL1/ERCC3/TERT/BRD7/WEE1/RRM1/RFWD3/BUB1/AVEN/CDK1/TRIAP1/RRM2/CKS1B/NABP1/STAT5B/ZWILCH/ANGEL2/CTDSP2/AURKAIP1/CD28/AURKB/RCC2/PTPN11/CACNB4/PLCB1/CHEK2/FOXO4/CDK10/MUC1/PBX1/ZFP36L1/ASAH2/ARID2/KANK2/TFDP1/PIM3/GIGYF2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PDXP/PRKDC/CDKN1C/AATF/SMARCB1/PTEN 157
GO:0045639 positive regulation of myeloid cell differentiation 51/3662 98/15509 9.61737e-10 2.28385e-08 1.37347e-08 SCIN/CD4/TYROBP/CD74/ACIN1/GATA1/TGFB1/HOXA5/CSF3/IFNG/NEDD9/MAPK14/IL17A/IL12B/IL5/STAT1/ID2/MPL/FOXO3/INHBA/PRMT1/LIF/NOTCH2/ABCB10/RB1/ARNT/POU4F2/POU4F1/PRKCA/KLF10/RUNX1/TAL1/PF4/SLC9B2/FADD/INPP5D/FOS/STAT5B/CTNNBIP1/CSF1/ZFP36L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/INPP5D 51
GO:0001503 ossification 143/3662 384/15509 9.7012e-10 2.29496e-08 1.38015e-08 MRC2/LTF/UFL1/IGF1/SNAI2/HGF/RUNX3/CASR/FGFR2/RHOA/CBFB/FGFR3/PRKACA/TP63/GLI2/GSK3B/ZMPSTE24/TXLNG/ACHE/MMP2/P2RX7/HNRNPC/MMP9/BMP7/RASSF2/SMAD7/GATA1/XYLT1/SFRP1/ERCC2/FBL/TGFB1/CLEC11A/PTN/BMPR1A/KAZALD1/DKK1/WNT3/CCDC47/DDX5/MAP2K6/AREG/ZBTB16/MDK/CALCA/CYP27B1/VDR/FBXO5/MAPK14/PEX7/SMAD5/WNT5A/HSPE1/FHL2/SPP1/PTK2B/CAT/SRGN/EGR2/RUNX2/RRBP1/BMP2/THRA/SBDS/TWSG1/MYBBP1A/HSD17B4/MEN1/LRP4/IL6/ADAMTS7/TFAP2A/ITGA11/SMAD6/FGF2/FBN2/COL2A1/TOB1/SMAD4/TNFRSF11A/EPHA2/CCN1/EGFR/IGFBP3/RBMX/NOTCH1/VEGFC/CRIM1/BMP6/KLF10/SLC26A2/MMP14/SKI/STC1/RUNX1/IL6R/PSMC2/ALOX15/WNT4/H3-3A/RANBP3L/SHH/TPM4/RBPJ/BMP1/MN1/ADRB2/PTK2/RIOX1/S1PR1/EIF2AK3/CEBPB/ESRRA/LEP/FAM20C/CTNNBIP1/PTPN11/SLC8A1/RFLNB/NOG/CSF1/NOTUM/PBX1/IFITM1/WNT7B/FZD9/COL13A1/RXRB/TNF/TNF/CEBPD/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/LOC102724560/CRIM1/WNT3/WNT3/PRKACA 143
GO:0032677 regulation of interleukin-8 production 45/3662 82/15509 9.885e-10 2.32955e-08 1.40095e-08 CD74/HYAL2/PTPRC/MAVS/TLR8/PYCARD/PRKD2/CD33/NOD1/SERPINE1/WNT5A/PARK7/CD244/IL1B/CHI3L1/PTPN22/IL6/IL10/TLR4/TLR3/SYK/NOD2/FADD/LGALS9/CD14/RELA/LEP/DDIT3/ADIPOQ/F2R/HMGB1/TLR7/ELANE/TNF/TMSB4X/TNF/ZNF580/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC/ELANE 45
GO:1904646 cellular response to amyloid-beta 30/3662 45/15509 1.04194e-09 2.44618e-08 1.47109e-08 IGF1/NGFR/FCGR2B/GSK3B/ICAM1/ABCC1/ITGA4/FOXO3/LRP1/BCL2L2/EPHB2/CD36/TLR4/IGF1R/APP/PARP1/GJA1/BCL2L11/VCAM1/CDK5/ADRB2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ABCC1 30
GO:0002676 regulation of chronic inflammatory response 20/3662 24/15509 1.0761e-09 2.51685e-08 1.51359e-08 FOXP3/IL4/TNFAIP3/IL10/CYP19A1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/CCL5/CCL5 20
GO:0042742 defense response to bacterium 109/3662 273/15509 1.10961e-09 2.58547e-08 1.55486e-08 MPO/CD4/LTF/SLC11A1/GRN/CYBA/SIRT2/GSDMB/ARG2/SEH1L/MAVS/P2RX7/LYZ/MARCHF2/CTSG/ACP5/PYCARD/IL27RA/HAMP/NOD1/SERPINE1/TNFSF8/AICDA/IL17A/IL12B/CCL20/GNLY/CD160/SEMG1/H2BC11/IL1B/RBCK1/RNASE1/SYT11/SFTPD/NOTCH2/CD36/AKIRIN2/IL6/IL10/TLR4/IRF8/EPHA2/LYST/LCN2/IL18/MR1/CXCL13/SHC1/IL6R/PRKCD/TLR3/SYK/MBL2/NOD2/RBPJ/FGA/CEBPB/RNF213/SELP/RAG2/F2/ADGRB1/MICA/H2BC21/PRG2/CARD9/ELANE/RPL39/TNF/HLA-E/PPP1R11/TNF/HLA-E/HLA-A/HLA-A/LTA/TNF/HLA-A/HLA-A/HLA-E/LTA/HLA-A/TNF/TNF/TNF/HLA-A/HLA-E/TNF/HLA-E/LTA/MICA/LTA/HLA-A/TNF/MICA/HLA-E/MICA/HLA-A/HLA-E/LTA/NAIP/HP/RNASE4/H2BC6/NAIP/H2BC7/ELANE/NAIP 109
GO:0060326 cell chemotaxis 113/3662 286/15509 1.14192e-09 2.6508e-08 1.59414e-08 CD74/HGF/F7/SPI1/FGFR1/MMP2/DNM1L/PDGFB/CTSG/FLT1/CCL22/CCL17/ABCC1/PRKD2/PIK3CG/PTN/MET/HSPB1/SERPINE1/CREB3/CXCL12/C1QBP/CCL2/MDK/CALCA/NEDD9/SMOC2/HBEGF/IL4/PDGFRB/WNT5A/CCL20/PADI2/CSF3R/PGF/PTK2B/CXCR4/NR4A1/NUP85/IL1B/CCR7/SBDS/KDR/RAC2/MTUS1/SFTPD/PDGFRA/EDNRB/IL6/IL10/CCN3/CCL21/THBS1/CYP19A1/FGF2/ARRB2/TNFRSF11A/EPHA2/RAB13/LYST/SLIT2/TPBG/NOTCH1/VEGFC/CXCL13/KIT/ITGB2/CXCR5/IL6R/CCR5/VCAM1/CXCR1/PF4/PRKCD/SYK/NOD2/CX3CR1/LGALS9/PTK2/CXCL8/S1PR1/SCG2/CCL11/BSG/IL16/CCL19/CYP7B1/CCR9/PLEC/CALR/CXCR2/CSF1R/CCR4/CSF1/PDE4B/CXCR3/CNR2/HMGB1/PPIA/DPP4/PARVA/TMSB4X/ZNF580/CCL5/CCL5/CCL4/CCL18/CCL4/MIF/CCL4/CCL18/CCL18/ABCC1 113
GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib 16/3662 17/15509 1.20497e-09 2.77636e-08 1.66965e-08 TAP2/HLA-E/TAP2/TAP2/HLA-E/TAP2/HLA-E/TAP2/TAP2/HLA-E/HLA-E/TAP2/HLA-E/HLA-E/TAP2/B2M 16
GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation 16/3662 17/15509 1.20497e-09 2.77636e-08 1.66965e-08 PTPN22/HLA-E/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-A/HLA-E 16
GO:2001198 regulation of dendritic cell differentiation 22/3662 28/15509 1.263e-09 2.89929e-08 1.74358e-08 FCGR2B/LILRB1/LGALS9/CEBPB/HMGB1/HLA-G/HLA-B/HLA-G/HLA-B/HLA-B/HLA-B/HLA-G/HLA-B/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1 22
GO:0035967 cellular response to topologically incorrect protein 59/3662 121/15509 1.32779e-09 3.03676e-08 1.82626e-08 MBTPS2/UFL1/BAK1/HSPA5/HERPUD1/EIF2AK2/ATXN3/DERL2/TMED2/PPP1R15A/BAX/BAG6/XBP1/UGGT2/BFAR/CREB3/TMEM33/HSPA8/CCND1/PACRG/HSPA9/SERP1/TMTC4/HSPA2/AKIRIN2/ABCB10/DERL1/TMBIM6/PIK3R1/DNAJB12/BAG3/HSPB8/BCL2L11/PPP1R15B/ATF3/VCP/EIF2AK3/DDIT3/PTPN2/ERN1/YOD1/CREB3L2/PRKN/RNF5/HSPA1L/BAG6/DAXX/DAXX/HSPA1L/HSPA1L/DAXX/BAG6/DAXX/BAG6/DAXX/BAG6/HSPA1L/BAG6/HSPA1L 59
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage 54/3662 107/15509 1.3523e-09 3.08145e-08 1.85313e-08 BAD/KDM1A/SNAI2/CD74/CD44/TNFRSF1B/BAK1/USP28/FNIP2/HIPK2/TMEM161A/TP63/MLH1/TP73/BAX/MSH2/BAG6/ABL1/PYCARD/CASP2/CXCL12/CLU/CDKN1A/DYRK2/BCL2L2/BCL2L10/BRCA2/BCL2A1/EPHA2/PIK3R1/BCL2L11/ZNF385A/RPL26/SHISA5/DDIT4/TRIAP1/BCL2L1/CHEK2/MUC1/BAG6/TNF/TNF/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/PRKDC/MIF 54
GO:0010631 epithelial cell migration 113/3662 287/15509 1.45142e-09 3.29519e-08 1.98167e-08 ITGA3/DCN/SNAI2/GRN/FLT4/ATP2B4/SP100/RHOA/ROCK1/FGFR1/PXN/APOH/ANGPT2/ABL1/PDGFB/MYH9/MMP9/CD40/FERMT1/RAB11A/GPI/PRKD2/TGFB1/PIK3CG/PTN/MET/HSPB1/TGFBR1/GATA3/LPXN/CORO1C/IFNG/PPARD/SMOC2/HBEGF/IL4/WNT5A/GADD45A/NRP2/TEK/PTK2B/PKN1/NR4A1/ID1/RRAS/STAT5A/KDR/APOE/LOXL2/GLUL/CCN3/THBS1/CYP1B1/FGF2/EGF/EPHA2/DUSP10/RAB13/RHOB/SLIT2/PLK2/NOTCH1/ITGB1/VEGFC/PRKCA/CXCL13/KIT/STC1/ADIPOR1/PKN3/EMC10/TGFBR2/NOS3/MAPRE2/ADAM9/EFNA1/PTK2/ZEB2/PRKCE/SCG2/JUN/SVBP/CALR/PTPN11/ADGRB1/PTP4A3/CIB1/CLN3/HMGB1/SRC/KANK2/DPP4/MTOR/CSNK2B/TNF/TMSB4X/TNF/ZNF580/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PDCD6/ITGB3/AKT3/GPI/PTEN 113
GO:1904892 regulation of receptor signaling pathway via STAT 51/3662 99/15509 1.53091e-09 3.46298e-08 2.08257e-08 PTPRC/PIBF1/DOT1L/TGFB1/JAK3/SH2B3/IFNG/IL12B/IL4/IL5/PPP2CA/HES1/GADD45A/PTK2B/LIF/EPHB2/ELP2/IL6/IL10/CYP1B1/EGF/NOTCH1/KIT/ADIPOR1/IL6R/IL24/CDK5/MST1/LEP/PTPN2/CDK5R1/F2/F2R/SOCS1/HGS/NF2/IFNA1/TNF/CRLF2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL10RB/GH1/PTPRC/CCL5/CCL5 51
GO:0046632 alpha-beta T cell differentiation 56/3662 113/15509 1.61468e-09 3.6392e-08 2.18855e-08 TMEM98/RUNX3/FOXP3/PRDM1/AP3D1/RHOA/CBFB/TBX21/IL4R/IL12RB1/ABL1/SMAD7/JAK3/TNFSF8/GATA3/ZBTB16/IFNG/IL12B/IL4/BCL6/CD86/ZAP70/MYB/CD80/BCL11B/RARA/AP3B1/IL6/HLX/IRF4/IL21/ARMC5/IL2RG/IL18/RUNX1/IL6R/TGFBR2/SHH/SYK/LGALS9/CCL19/KLHL25/SOCS1/LILRB4/HMGB1/ENTPD7/MTOR/PNP/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/LILRB4/HLA-DRA/LILRB4/LILRB4 56
GO:0009612 response to mechanical stimulus 87/3662 205/15509 1.62461e-09 3.64831e-08 2.19403e-08 BAD/MPO/MAP3K14/FAS/BAK1/CYBA/KCNQ1/MAP2K4/RHOA/MMP2/P2RX7/ANGPT2/NFKBIA/CD40/TLR8/PIEZO1/GPI/MTPN/PTN/CASP2/ENG/CXCL12/MAPK8/RPS6KB1/MDK/MAPK14/STAT1/IGFBP2/GADD45A/SLC2A1/PKD2/PPL/TNFRSF10B/PTK2B/TNFRSF8/CXCR4/KCNJ2/IL1B/FOSB/CHI3L1/SERPINE2/TLR4/KIAA0319/THBS1/FGF2/IGF1R/TNFRSF11A/GSN/BAG3/BMP6/XPC/MMP14/KIT/BTG2/CAPN2/ANKRD23/TGFBR2/TLR3/STRBP/FADD/PTK2/MAP3K2/FOS/CDH2/RELA/DAG1/FOSL1/JUN/PLEC/SLC8A1/CSF1/TLR7/SRC/LHFPL5/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SHANK3/ITGB3/TXNIP/GPI 87
GO:0042176 regulation of protein catabolic process 126/3662 330/15509 1.63553e-09 3.65956e-08 2.2008e-08 OSBPL7/RHBDF1/MYLIP/HFE/PSMC4/RNF14/UFL1/TNFRSF1B/CDH1/HERPUD1/CTSA/ATXN3/ROCK1/SIRT2/VPS35/PRKACA/NSF/MKRN2/SIRT6/UBE2K/LRP2/GSK3B/XPO1/PSMC5/PSME1/HECTD1/BAG6/HSP90AB1/MARCHF2/PSMC6/EEF1A2/USP14/SMAD7/N4BP1/AXIN1/SNRNP70/SGTA/HAMP/GSK3A/DVL1/PSMD3/SH3D19/CD81/IFNG/USP5/WNT5A/ODC1/PARK7/CDC20/TNFAIP3/FBXL5/RAD23B/CLU/LRP1/USP9X/IL1B/PIN1/MGAT3/CBFA2T3/APOE/PSME3/NDFIP1/HSPBP1/APC/SERPINE2/IL10/SORL1/RDX/FURIN/CSNK1D/SMAD4/DTL/PLK2/GNA12/EGFR/TLK2/MSN/OGT/SNX12/EIF3H/ALAD/FOXO1/RNF144A/USP25/EEF1A1/CUL4B/PSMC2/RYBP/RCHY1/SHH/VCP/PSMC3/BTRC/ADAM9/RELA/PSMD1/GLMN/PSMD2/CHMP6/NQO1/ADGRB1/RGMA/ANXA2/CHEK2/PRKN/HGS/USP7/ATG7/SVIP/BAG6/TNF/TNF/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/CEBPA/PRKACA/F8A1/ITCH 126
GO:0032637 interleukin-8 production 45/3662 83/15509 1.66719e-09 3.717e-08 2.23534e-08 CD74/HYAL2/PTPRC/MAVS/TLR8/PYCARD/PRKD2/CD33/NOD1/SERPINE1/WNT5A/PARK7/CD244/IL1B/CHI3L1/PTPN22/IL6/IL10/TLR4/TLR3/SYK/NOD2/FADD/LGALS9/CD14/RELA/LEP/DDIT3/ADIPOQ/F2R/HMGB1/TLR7/ELANE/TNF/TMSB4X/TNF/ZNF580/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC/ELANE 45
GO:0002820 negative regulation of adaptive immune response 40/3662 70/15509 1.68454e-09 3.7422e-08 2.2505e-08 HFE/PARP3/FOXP3/FCGR2B/TBX21/IL4R/PTPRC/SMAD7/LILRB1/IL27RA/JAK3/AHR/PPP3CB/IL4/BCL6/CD160/ARG1/FOXJ1/NDFIP1/ALOX15/NOD2/LILRB4/CD55/CR1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/PTPRC/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 40
GO:0002366 leukocyte activation involved in immune response 105/3662 262/15509 1.74908e-09 3.87171e-08 2.32838e-08 ITGAL/TMEM98/ST3GAL1/BTK/TYROBP/SLC11A1/CD74/GRN/GAB2/PARP3/C12orf4/FOXP3/KARS1/SPI1/FCGR2B/TBX21/MLH1/STXBP2/IL4R/PTPRC/LAT2/ICAM1/MSH2/IL12RB1/ABL1/XBP1/CD40/SMAD7/GATA1/CD40LG/PYCARD/NBN/LILRB1/IL27RA/TGFB1/JAK3/PIK3CG/EXOSC3/GATA3/NSD2/MDK/CD81/POU2AF1/IFNG/AICDA/IL12B/IL4/BCL6/CD86/SNX4/MYB/VAMP8/NR4A3/PTK2B/CD80/CD244/SHLD2/RAC2/NDFIP1/RARA/NOTCH2/LCP1/IL6/HLX/IL10/STXBP1/TLR4/IRF4/IL21/SLC15A4/IRF8/CPLX2/IL18/KIT/CD1C/ITGB2/IL6R/TNFSF13/SYK/CX3CR1/LGALS9/PTAFR/ITGAM/PRKCE/CCL19/LIG4/RAG2/CD19/CD28/HMGB1/IFNA1/ENTPD7/MTOR/CR1/CD177/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/PTPRC/LILRB1/LILRB1/LILRB1/HLA-DRA/LILRB1 105
GO:0002823 negative regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains 38/3662 65/15509 1.75859e-09 3.87892e-08 2.33272e-08 HFE/PARP3/FOXP3/FCGR2B/TBX21/IL4R/PTPRC/SMAD7/LILRB1/IL27RA/JAK3/AHR/PPP3CB/IL4/BCL6/ARG1/FOXJ1/NDFIP1/NOD2/LILRB4/CD55/CR1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/PTPRC/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 38
GO:0036037 CD8-positive, alpha-beta T cell activation 31/3662 48/15509 1.79333e-09 3.94152e-08 2.37036e-08 HFE/RUNX3/CBFB/LILRB1/TNFSF8/PTPN22/RUNX1/SOCS1/LILRB4/HLA-E/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-A/HLA-E/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 31
GO:0002285 lymphocyte activation involved in immune response 80/3662 184/15509 1.8914e-09 4.13806e-08 2.48856e-08 ITGAL/TMEM98/ST3GAL1/SLC11A1/CD74/PARP3/FOXP3/SPI1/FCGR2B/TBX21/MLH1/IL4R/PTPRC/ICAM1/MSH2/IL12RB1/ABL1/XBP1/CD40/SMAD7/CD40LG/NBN/LILRB1/IL27RA/TGFB1/JAK3/EXOSC3/GATA3/NSD2/MDK/CD81/POU2AF1/IFNG/AICDA/IL12B/IL4/BCL6/CD86/MYB/PTK2B/CD80/CD244/SHLD2/NDFIP1/RARA/NOTCH2/LCP1/IL6/HLX/IL10/TLR4/IRF4/IL21/SLC15A4/IRF8/IL18/CD1C/IL6R/TNFSF13/LGALS9/CCL19/LIG4/RAG2/CD19/CD28/HMGB1/IFNA1/ENTPD7/MTOR/CR1/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/PTPRC/LILRB1/LILRB1/LILRB1/HLA-DRA/LILRB1 80
GO:0046425 regulation of receptor signaling pathway via JAK-STAT 49/3662 94/15509 1.89611e-09 4.13806e-08 2.48856e-08 PTPRC/PIBF1/DOT1L/JAK3/SH2B3/IFNG/IL12B/IL4/IL5/PPP2CA/HES1/GADD45A/PTK2B/LIF/EPHB2/ELP2/IL6/IL10/CYP1B1/EGF/NOTCH1/KIT/ADIPOR1/IL6R/IL24/CDK5/MST1/LEP/PTPN2/CDK5R1/F2/F2R/SOCS1/HGS/NF2/IFNA1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL10RB/GH1/PTPRC/CCL5/CCL5 49
GO:0048015 phosphatidylinositol-mediated signaling 76/3662 172/15509 1.97594e-09 4.29715e-08 2.58423e-08 WNT16/DCN/IGF1/HGF/GAB2/PREX2/ERBB3/SIRT2/FGFR1/OSM/PIK3IP1/PDGFB/PPP1R16B/FLT1/TSC2/PIK3CG/GATA3/UNC5B/CSF3/RPS6KB1/C1QBP/PPARD/PDGFRB/FN1/CD160/TEK/CAT/FLT3/BECN1/KDR/PDGFRA/SERPINE2/PLCB2/PLCE1/FGF2/EGF/IGF1R/KCNH1/PDGFC/PIK3R1/EGFR/OGT/NTRK2/PLCH2/IL18/KIT/PLCD3/GPER1/PTK2/PTAFR/SEMA3E/SELP/LEP/CD28/F2/F2R/CSF1R/PLCB1/ROR1/ZFP36L1/PRR5/PLCD1/SRC/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/CCL5/CCL5/PTEN 76
GO:0050868 negative regulation of T cell activation 61/3662 128/15509 2.19992e-09 4.76751e-08 2.8671e-08 HFE/CD74/RUNX3/FOXP3/CBFB/FCGR2B/TBX21/IL4R/ARG2/CTSG/SMAD7/LILRB1/JAK3/MDK/IL4/BCL6/CD86/ARG1/CD80/TWSG1/FOXJ1/NDFIP1/SFTPD/PTPN22/IL2RA/HLX/IL10/TNFRSF21/RUNX1/CTLA4/CASP3/SHH/PRDX2/LGALS9/CEBPB/GLMN/RAG2/PTPN2/SOCS1/LILRB4/HMGB1/PDCD1LG2/NRARP/CR1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/PTEN/ITCH 61
GO:0010934 macrophage cytokine production 30/3662 46/15509 2.31827e-09 4.98912e-08 3.00037e-08 CD74/P2RX7/ACP5/PYCARD/LILRB1/TGFB1/NOD1/WNT5A/CD36/TLR4/NLRX1/MAPKAPK2/TLR3/NOD2/PRG2/CARD9/TLR7/UBE2J1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1 30
GO:0010935 regulation of macrophage cytokine production 30/3662 46/15509 2.31827e-09 4.98912e-08 3.00037e-08 CD74/P2RX7/ACP5/PYCARD/LILRB1/TGFB1/NOD1/WNT5A/CD36/TLR4/NLRX1/MAPKAPK2/TLR3/NOD2/PRG2/CARD9/TLR7/UBE2J1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1 30
GO:0007584 response to nutrient 66/3662 143/15509 2.59536e-09 5.56611e-08 3.34736e-08 SNAI2/CASR/F7/OXCT1/XBP1/BMP7/SFRP1/HAMP/USF2/RPS6KB1/CCND1/FOLR1/CYP27B1/VDR/PPARD/IL1A/STAT1/IGFBP2/ARG1/SPP1/DNMT3A/TRIM25/CAT/TRIM24/RUNX2/BECN1/ALDH1A2/EPO/ASS1/RARA/CYP1B1/IGF1R/CYP1A1/ENSA/PKLR/OGT/ALAD/STC1/VCAM1/TGFBR2/TNFRSF11B/CYBB/AQP3/SLC27A4/NOD2/MN1/MGMT/LEP/LPL/A2M/TYMS/NQO1/ADIPOQ/SLC8A1/AKR1C3/KANK2/F5/MTOR/LTA/LTA/LTA/LTA/LTA/ADSL/PKLR/LOC102724560 66
GO:0140014 mitotic nuclear division 111/3662 283/15509 2.61631e-09 5.59168e-08 3.36274e-08 CDC27/BAZ1B/IGF1/SPAST/ARID1B/RHOA/SIRT2/CDC42/SMC1A/NDE1/ACTB/SPAG5/NDC80/PIBF1/ATRX/SEH1L/CHMP5/ZW10/TPX2/NSFL1C/ANAPC5/BIRC5/NUDC/KIF4A/CDC6/BCL7C/SMARCB1/PDGFB/MYBL2/BMP7/CHMP4B/UBE2I/RAB11A/ARHGEF10/BCCIP/SMC3/SMARCD2/BCL7A/FBXO5/CUL9/MACROH2A1/PDGFRB/SMC4/KAT2B/IL1A/CDC20/NSL1/ARID1A/SLF2/TEX14/NAA50/PDS5A/CENPK/OBSL1/IL1B/BECN1/PIN1/PKMYT1/MAU2/CEP85/CHMP1A/CCNB1/PSRC1/CDCA8/APC/BORA/NUMA1/NUSAP1/KIF23/CENPE/EGF/RB1/KIF2C/CENPC/BOD1/NCAPG2/MKI67/SPC25/SMARCA5/USP16/MAP9/REEP3/BRD7/GOLGA2/BUB1/KAT5/ZWILCH/BANF1/AURKAIP1/CHMP6/ANKLE2/CD28/AURKB/CHEK2/KMT5A/DRG1/ARID2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/KIFC1/PDXP/LSM14A/SMARCB1/NDE1/SPICE1 111
GO:2000514 regulation of CD4-positive, alpha-beta T cell activation 42/3662 76/15509 2.67449e-09 5.69398e-08 3.42426e-08 RUNX3/FOXP3/CBFB/TBX21/IL4R/ARG2/IL12RB1/SMAD7/JAK3/GATA3/CD81/IFNG/IL12B/IL4/BCL6/CD86/CD160/MYB/CD80/TWSG1/NDFIP1/RARA/IL2RA/HLX/IRF4/IL2RG/IL18/RUNX1/TGFBR2/LGALS9/CCL19/CD28/KLHL25/SOCS1/HMGB1/CD55/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/ITCH 42
GO:0031098 stress-activated protein kinase signaling cascade 96/3662 235/15509 2.68255e-09 5.69398e-08 3.42426e-08 WNT16/PAFAH1B1/NOX1/MAPK8IP2/HGF/FAS/CASR/FLT4/EIF2AK2/TRAF1/HIPK2/MAP2K4/SPI1/RHOA/FCGR2B/TRAF4/OPRK1/RNF13/ZMPSTE24/MECOM/GADD45B/BIRC7/RASSF2/AXIN1/PYCARD/SFRP1/NOD1/FKTN/AMBP/MAPK8/MAP2K6/CRYAB/FOXM1/MAPK14/WNT5A/IL1A/GADD45A/PRDX1/PTK2B/IL1B/BMP2/CCR7/PRMT1/ZFP36/EDA2R/TRAF3/MEN1/PTPN22/MDFIC/CCM2/TLR4/CCL21/MAP3K12/IGF1R/APP/DUSP10/ARL6IP5/EGFR/FOXO1/MBIP/MAPKAPK2/TLR3/NOD2/SEMA4C/LGALS9/GPS1/CCL19/LEP/HRAS/PLCB1/IRAK1/PRKN/ZFP36L1/CARD9/WNT7B/HMGB1/PPIA/TLR7/MAP3K5/TNF/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF/NAIP/NAIP/NAIP/ITCH 96
GO:0006338 chromatin remodeling 125/3662 329/15509 2.70018e-09 5.71184e-08 3.435e-08 KDM1A/BAZ1B/ARID1B/FOXP3/BICRA/KDM4A/SIRT2/MBD3/TP63/ACTB/SIRT6/ATRX/MECOM/RAD54L/ESR1/HNRNPC/SUPT16H/BCL7C/CECR2/SMARCB1/CHD8/ACTR5/SMARCA1/RBBP7/AXIN1/CHRAC1/DOT1L/ZNHIT1/EZH2/GATA3/SMARCD2/EZH1/BCL7A/CHD4/HCFC2/AICDA/FAM172A/MACROH2A1/KAT2B/INO80D/SF3B1/HDAC1/PADI2/KDM5B/DR1/ARID1A/MYB/DNMT3A/HELLS/CHD6/H1-3/H2BC11/DEK/YEATS4/HP1BP3/DNMT1/MYBBP1A/WBP2/LOXL2/PPHLN1/ANP32B/HMGA1/TET1/SMARCAL1/RB1/ANP32E/SSRP1/HMGA2/SMARCA5/H2BC5/CHAF1B/PADI4/CTBP1/LMNA/TAF6L/RBBP4/MYSM1/H3-3A/NUDT5/BRD7/GATAD2A/CHAF1A/H1-4/BRD3/PPM1D/HCFC1/KAT5/NPM1/H2AC25/SETD2/H2BC21/H1-2/CENPP/H2AX/H1-0/ARID2/HMGB1/H2BC26/PHF2/L3MBTL3/BRD2/DAXX/DAXX/DNAJC9/BRD2/DAXX/DAXX/BRD2/DAXX/H2BC15/BRD2/BRD2/H4C15/H4C14/H4C12/H2BC6/H3C6/SMARCB1/TADA2A/H4C5/H4C4/H2BC7/H3C10/PADI4/H3C2 125
GO:0060562 epithelial tube morphogenesis 121/3662 316/15509 2.81617e-09 5.93695e-08 3.57038e-08 HOXA11/CASR/NTN1/TIE1/FGFR2/RHOA/PRKACA/GLI2/SIRT6/TULP3/LRP2/PGR/TMED2/KDM2B/ESR1/HECTD1/ABL1/CECR2/MTHFD1/BMP7/LAMA1/NDRG4/TSC2/EYA1/SFRP1/PRKD2/TGFB1/TMEM59L/MET/HOXA5/ENG/DVL1/GATA3/AREG/FOLR1/MDK/VDR/NPHP3/WNT5A/HES1/KDM5B/PKD2/GNA13/MTHFD1L/CXCR4/SOX4/BMP2/KDR/PODXL/LAMA5/RARA/KRAS/NOTCH2/AHI1/SPRY2/CCM2/NKX2-1/FGF2/EGF/BBS4/ITGAX/GREB1L/SMAD4/EPHA2/RHOB/SLIT2/ADAMTS16/KLHL3/NOTCH1/NODAL/MMP14/SKI/ARHGAP35/DVL3/WNT4/VANGL2/RBM15/TGFBR2/CASP3/SHH/BTRC/RBPJ/SEMA4C/ARL13B/SEMA3E/CCL11/RARG/DAG1/GLMN/CTNNBIP1/CXCR2/SETD2/RGMA/CSF1R/NKX2-5/NOG/CSF1/PBX1/SRC/NRARP/BRD2/FKBPL/CSNK2B/TNF/TCTN1/TNF/BRD2/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/BRD2/TNF/CSNK2B/BRD2/BRD2/PRKACA 121
GO:0090132 epithelium migration 113/3662 290/15509 2.94058e-09 6.1782e-08 3.71546e-08 ITGA3/DCN/SNAI2/GRN/FLT4/ATP2B4/SP100/RHOA/ROCK1/FGFR1/PXN/APOH/ANGPT2/ABL1/PDGFB/MYH9/MMP9/CD40/FERMT1/RAB11A/GPI/PRKD2/TGFB1/PIK3CG/PTN/MET/HSPB1/TGFBR1/GATA3/LPXN/CORO1C/IFNG/PPARD/SMOC2/HBEGF/IL4/WNT5A/GADD45A/NRP2/TEK/PTK2B/PKN1/NR4A1/ID1/RRAS/STAT5A/KDR/APOE/LOXL2/GLUL/CCN3/THBS1/CYP1B1/FGF2/EGF/EPHA2/DUSP10/RAB13/RHOB/SLIT2/PLK2/NOTCH1/ITGB1/VEGFC/PRKCA/CXCL13/KIT/STC1/ADIPOR1/PKN3/EMC10/TGFBR2/NOS3/MAPRE2/ADAM9/EFNA1/PTK2/ZEB2/PRKCE/SCG2/JUN/SVBP/CALR/PTPN11/ADGRB1/PTP4A3/CIB1/CLN3/HMGB1/SRC/KANK2/DPP4/MTOR/CSNK2B/TNF/TMSB4X/TNF/ZNF580/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PDCD6/ITGB3/AKT3/GPI/PTEN 113
GO:0051052 regulation of DNA metabolic process 168/3662 475/15509 3.0441e-09 6.37409e-08 3.83327e-08 KDM1A/UPF1/DBF4/HGF/PARP3/ARID1B/FOXP3/RAD51/FAM168A/TMEM161A/MAP2K4/SPI1/SMG6/MBD3/TBX21/GLI2/ACTB/MLH1/SIRT6/XRCC5/PTPRC/ZMPSTE24/ATRX/NOX4/BAX/ATXN7L3/MAPKAPK5/FUS/HNRNPC/CDC6/MSH2/BRPF3/HSP90AB1/CDC7/BCL7C/SMARCB1/TFIP11/PDGFB/GINS1/CD40/ACTR5/RBBP8/JADE3/EYA1/NBN/CHRAC1/ERCC2/IL27RA/PRKD2/TGFB1/GSK3A/EXOSC3/GATA3/SMC3/RECQL5/SMARCD2/NSD2/BCL7A/FOXM1/AICDA/FBXO5/EYA4/SMOC2/IL4/RAD50/PPP2CA/PDGFRB/BCL6/KPNA1/XRN1/KAT2B/INO80D/ARID1A/SLF2/PTK2B/PDS5A/SHLD2/MORF4L2/USP9X/H1-3/CDKN1A/DEK/YEATS4/AUNIP/POT1/DKC1/NDFIP1/MEN1/HNRNPA1/CCT7/TAF5L/EPC2/IL6/IL10/CYP1B1/ACTR2/SMARCAL1/FGF2/EGF/SLC15A4/NABP2/BRCA2/CUL4A/IGF1R/PIF1/ARRB2/PARP1/CCNA2/EGFR/RADX/PPP4C/HMGA2/SMARCA5/CCDC117/MRNIP/DBF4B/TNFSF13/TAF6L/S100A11/PRKCD/BRD7/CCT2/RNF169/MCM7/ZNF91/NUDT16L1/H1-4/CDK1/MGMT/TADA3/EXOSC10/DCP2/KAT5/KCTD13/RMI2/ZBTB38/MAGEF1/CD28/TAF7/AURKB/MAPK15/ADIPOQ/NPM1/SETD2/USP7/H1-2/H2AX/H1-0/ARID2/HMGB1/TRRAP/SRC/TFDP1/SMG5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/TEN1/RTEL1/PTPRC/SMARCB1/TINF2 168
GO:0001667 ameboidal-type cell migration 146/3662 400/15509 3.13335e-09 6.53889e-08 3.93237e-08 ITGA3/PAFAH1B1/DCN/SNAI2/GRN/FLT4/ATP2B4/SP100/RHOA/ROCK1/HYAL2/CDC42/FGFR1/PXN/APOH/ANGPT2/ABL1/PDGFB/MYH9/MMP9/CD40/BMP7/FERMT1/RAB11A/SYDE1/GPI/PRKD2/TGFB1/HAS1/PIK3CG/PTN/MET/HSPB1/TGFBR1/GATA3/ACTA2/C1QBP/LPXN/FOLR1/CORO1C/IFNG/PPARD/SMOC2/HBEGF/IL4/AMOTL2/WNT5A/ITGA4/FN1/GADD45A/NRP2/GNA13/TEK/PTK2B/PKN1/NR4A1/ID1/RRAS/STAT5A/KDR/APOE/LAMA5/AKAP12/CAP1/LOXL2/GLUL/EDNRB/CCN3/THBS1/CYP1B1/FGF2/EGF/EPHA2/DUSP10/RAB13/RHOB/SLIT2/PLK2/TPBG/GNA12/NOTCH1/ITGB1/ARID5B/VEGFC/GJA1/PRKCA/CXCL13/NODAL/KIT/APPL1/DMTN/STC1/ADIPOR1/PKN3/EMC10/TGFBR2/PITX2/SHH/NOS3/MAPRE2/ADAM9/SEMA4C/EFNA1/PTK2/ZEB2/SEMA3E/CDH2/PRKCE/SCG2/JUN/SVBP/PLEC/RCC2/CALR/PTPN11/ADGRB1/SLC8A1/PTP4A3/CIB1/YTHDF3/CLN3/HMGB1/SRC/KANK2/DPP4/MTOR/CSNK2B/TNF/TMSB4X/TNF/ZNF580/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PDCD6/ITGB3/AKT3/GPI/PTEN 146
GO:0071887 leukocyte apoptotic process 55/3662 112/15509 3.44195e-09 7.1588e-08 4.30518e-08 ST3GAL1/BTK/CD74/FAS/BAK1/ST6GAL1/ARG2/BAX/P2RX7/BIRC7/LILRB1/CLC/PRKD2/KDELR1/JAK3/CXCL12/BCL6/WNT5A/FASLG/GPAM/PKN1/CCR7/IRF3/BCL11B/IL2RA/IL6/IL10/CCL21/TNFRSF21/BCL2L11/MERTK/TSC22D3/CASP3/RAG1/NOD2/FADD/LGALS9/PRELID1/EFNA1/BCL2L1/PTCRA/ORMDL3/CCL19/AURKB/CXCR2/CHEK2/NOC2L/CCL5/CCL5/LILRB1/LILRB1/MIF/LILRB1/LILRB1/PTEN 55
GO:0045066 regulatory T cell differentiation 31/3662 49/15509 3.77749e-09 7.83039e-08 4.70906e-08 FOXP3/MDK/IFNG/BCL6/FOXO3/DUSP10/IL2RG/CTLA4/LGALS9/KAT5/CD28/KLHL25/SOCS1/LILRB4/CR1/HLA-G/HLA-DRA/HLA-G/HLA-DRA/HLA-DRA/HLA-G/HLA-G/HLA-DRA/HLA-G/HLA-G/HLA-G/LILRB4/HLA-G/HLA-DRA/LILRB4/LILRB4 31
GO:0002664 regulation of T cell tolerance induction 22/3662 29/15509 4.05976e-09 8.38747e-08 5.04408e-08 FOXP3/CLC/IL2RA/TGFBR2/LILRB4/HLA-G/HLA-B/HLA-G/HLA-B/HLA-B/HLA-B/HLA-G/HLA-B/HLA-G/HLA-G/HLA-G/HLA-G/LILRB4/HLA-G/LILRB4/LILRB4/ITCH 22
GO:0090130 tissue migration 114/3662 295/15509 4.37864e-09 9.01621e-08 5.42219e-08 ITGA3/DCN/SNAI2/GRN/FLT4/ATP2B4/SP100/RHOA/ROCK1/FGFR1/PXN/APOH/ANGPT2/ABL1/PDGFB/MYH9/MMP9/CD40/FERMT1/RAB11A/GPI/PRKD2/TGFB1/PIK3CG/PTN/MET/HSPB1/TGFBR1/GATA3/ACTA2/LPXN/CORO1C/IFNG/PPARD/SMOC2/HBEGF/IL4/WNT5A/GADD45A/NRP2/TEK/PTK2B/PKN1/NR4A1/ID1/RRAS/STAT5A/KDR/APOE/LOXL2/GLUL/CCN3/THBS1/CYP1B1/FGF2/EGF/EPHA2/DUSP10/RAB13/RHOB/SLIT2/PLK2/NOTCH1/ITGB1/VEGFC/PRKCA/CXCL13/KIT/STC1/ADIPOR1/PKN3/EMC10/TGFBR2/NOS3/MAPRE2/ADAM9/EFNA1/PTK2/ZEB2/PRKCE/SCG2/JUN/SVBP/CALR/PTPN11/ADGRB1/PTP4A3/CIB1/CLN3/HMGB1/SRC/KANK2/DPP4/MTOR/CSNK2B/TNF/TMSB4X/TNF/ZNF580/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PDCD6/ITGB3/AKT3/GPI/PTEN 114
GO:0006979 response to oxidative stress 146/3662 402/15509 4.59422e-09 9.4288e-08 5.67032e-08 BAD/WNT16/CD38/MPO/NOX1/BTK/HGF/GLRX2/BAK1/AIFM2/TMEM161A/HYAL2/SIRT2/SLC25A24/MMP2/SLC23A2/PXN/PTGS1/ABL1/GSKIP/APEX1/DHRS2/MMP9/BMP7/ABCC1/GSR/ERCC2/MET/HSPB1/EZH2/MAPK8/PPIF/AREG/CRYAB/MACROH2A1/PDGFRB/IL1A/STAT1/SDC1/EPAS1/PARK7/PRDX1/PRDX6/TNFAIP3/ARG1/FOXO3/PKD2/NR4A3/PTK2B/CAT/CHD6/STAU1/BECN1/TRAP1/MGAT3/APOE/PXDN/CYP2E1/SESN2/C19orf12/PRKAA1/PDGFRA/CD36/IL6/IL10/TLR4/IL18BP/CYP1B1/MEAK7/SOD1/APP/ARNT/PARP1/RHOB/ARL6IP5/EGFR/NONO/NAPRT/ALAD/SESN3/FOXO1/NR4A2/MMP14/FANCC/PPP1R15B/NDUFS2/TBC1D24/SELENON/CAPN2/ERCC3/FABP1/PRKCD/CASP3/NOS3/TP53INP1/FXN/MBL2/GPX4/PRDX2/ADAM9/RGS14/CDK1/FOS/MGMT/RELA/ATP2A2/BANF1/FOSL1/JUN/ERN1/NQO1/ADIPOQ/SLC8A1/PRKN/AKR1C3/PPIA/DAPK1/SRC/MAP3K5/ND6/ZNF277/TNF/TNF/MICB/GPX3/ZNF580/CHUK/TNF/MICB/MICB/TNF/TNF/TNF/TNF/MICB/MICB/TNF/GAS5/MICB/HBB/HP/TXNIP/SRXN1/PCGF2/TPO/ABCC1 146
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation 80/3662 187/15509 4.68214e-09 9.57752e-08 5.75975e-08 CD4/IGF1/CNTN1/CD74/HGF/CD44/ERBB3/FGFR3/PTPRC/DLG3/PIBF1/NOX4/ABL1/OSM/PDGFB/CD40/ADNP/GATA1/EHD4/TGFB1/CSF3/UNC119/AREG/HPX/CD81/IFNG/NEDD9/HBEGF/IL12B/IL4/IL5/HES1/PTK2B/CD80/FLT3/LIF/EPO/LRP4/CD36/IL6/IL21/EGF/ARRB2/EGFR/IL18/BMP6/KIT/IL6R/IL24/RICTOR/IL3/CSF2/SYK/NOD2/EFNA1/ALK/CSPG4/LEP/PTPN11/PAK2/ADIPOQ/CSF1R/SRC/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/GH1/PECAM1/PTPRC/CCL5/CD24/CCL5/MIF 80
GO:0030183 B cell differentiation 63/3662 136/15509 4.95652e-09 1.00808e-07 6.06241e-08 BAD/CD79B/ST3GAL1/BTK/HMGB3/BAK1/SPI1/KLF6/TCF3/FCGR2B/PTPRC/BAX/MSH2/ABL1/XBP1/CD40LG/SFRP1/IL7/LYL1/CD79A/JAK3/EZH2/POU2AF1/AICDA/IL4/BCL6/ITGA4/ID2/PTK2B/FLT3/INHBA/NOTCH2/IL6/IL10/IL21/IRF8/DCAF1/PIK3R1/IL2RG/ITGB1/ZFP36L2/HHEX/MS4A1/MMP14/KIT/VCAM1/SYK/RAG1/RBPJ/INPP5D/STAT5B/RAG2/PTPN2/CD19/ZFP36L1/FZD9/PAX5/IFNA1/NTRK1/CR1/PRKDC/PTPRC/INPP5D 63
GO:0032735 positive regulation of interleukin-12 production 30/3662 47/15509 4.9607e-09 1.00808e-07 6.06241e-08 CD40/CD40LG/MDK/IFNG/MAPK14/IL17A/IL12B/CCR7/IRF5/CD36/TLR4/IRF8/TLR3/SYK/NOD2/LGALS9/IL16/CCL19/RELA/LEP/PLCB1/HMGB1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 30
GO:0000302 response to reactive oxygen species 77/3662 178/15509 4.98397e-09 1.0095e-07 6.07094e-08 BAD/MPO/BTK/HGF/GLRX2/BAK1/HYAL2/MMP2/PXN/ABL1/APEX1/MMP9/BMP7/MET/EZH2/MAPK8/PPIF/AREG/CRYAB/PDGFRB/IL1A/STAT1/SDC1/PARK7/PRDX1/TNFAIP3/ARG1/FOXO3/PKD2/NR4A3/PTK2B/CAT/BECN1/TRAP1/APOE/CYP2E1/SESN2/PRKAA1/PDGFRA/CD36/IL6/IL10/IL18BP/CYP1B1/SOD1/RHOB/EGFR/SESN3/FANCC/PPP1R15B/CAPN2/FABP1/PRKCD/CASP3/NOS3/FXN/PRDX2/ADAM9/CDK1/FOS/RELA/FOSL1/JUN/ERN1/NQO1/SLC8A1/AKR1C3/SRC/MAP3K5/ND6/ZNF277/ZNF580/CHUK/HBB/HP/TXNIP/PCGF2 77
GO:1903038 negative regulation of leukocyte cell-cell adhesion 64/3662 139/15509 5.06696e-09 1.02296e-07 6.15193e-08 HFE/CD74/RUNX3/FOXP3/CBFB/FCGR2B/TBX21/IL4R/ARG2/CTSG/SMAD7/LILRB1/JAK3/CXCL12/MDK/IL4/BCL6/CD86/ARG1/CD80/TWSG1/FOXJ1/ASS1/NDFIP1/SFTPD/PTPN22/IL2RA/HLX/IL10/CCL21/TNFRSF21/RUNX1/CTLA4/CASP3/SHH/PRDX2/LGALS9/CEBPB/GLMN/RAG2/PTPN2/SOCS1/LILRB4/HMGB1/PDCD1LG2/NRARP/CR1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/PTEN/ITCH 64
GO:0051403 stress-activated MAPK cascade 93/3662 228/15509 5.178e-09 1.04199e-07 6.26634e-08 WNT16/PAFAH1B1/NOX1/MAPK8IP2/HGF/FAS/CASR/FLT4/EIF2AK2/TRAF1/HIPK2/MAP2K4/SPI1/FCGR2B/TRAF4/OPRK1/MECOM/GADD45B/BIRC7/RASSF2/AXIN1/PYCARD/SFRP1/NOD1/FKTN/AMBP/MAPK8/MAP2K6/CRYAB/FOXM1/MAPK14/WNT5A/IL1A/GADD45A/PRDX1/PTK2B/IL1B/BMP2/CCR7/PRMT1/ZFP36/EDA2R/TRAF3/MEN1/PTPN22/MDFIC/CCM2/TLR4/CCL21/MAP3K12/IGF1R/APP/DUSP10/ARL6IP5/EGFR/FOXO1/MBIP/MAPKAPK2/TLR3/NOD2/SEMA4C/LGALS9/GPS1/CCL19/LEP/HRAS/PLCB1/IRAK1/PRKN/ZFP36L1/CARD9/WNT7B/HMGB1/PPIA/TLR7/MAP3K5/TNF/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF/NAIP/NAIP/NAIP/ITCH 93
GO:0043523 regulation of neuron apoptotic process 86/3662 206/15509 5.22556e-09 1.04816e-07 6.30342e-08 TYROBP/GRN/HIPK2/ERBB3/MAP2K4/RHOA/ROCK1/BAX/KDM2B/AARS1/MSH2/HSP90AB1/ABL1/MYBL2/ADNP/IL27RA/GPI/GSK3A/CASP2/GATA3/UNC5B/CCL2/ZPR1/CCND1/MDK/PARK7/FASLG/FOXO3/PTK2B/CNTFR/KDR/APOE/KRAS/NGF/SRPK2/IL10/STXBP1/TFAP2A/MAP3K12/ARRB2/SOD1/PARP1/NONO/NTRK2/POU4F1/BCL2L11/NR4A2/BTG2/CASP3/TERT/FOXQ1/CDK5/NSMF/CX3CR1/ITGAM/SEMA3E/BCL2L1/CEBPB/LIG4/HRAS/DDIT3/BDNF/CDK5R1/JUN/NQO1/F2R/PRKN/CLN3/FZD9/SYNGAP1/NTRK1/GPRASP3/TNF/AKT1S1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NEFL/NAIP/GPI 86
GO:0045787 positive regulation of cell cycle 118/3662 309/15509 5.30969e-09 1.0616e-07 6.38425e-08 CDC27/KMT2E/DBF4/PAF1/PAFAH1B1/IGF1/SPAST/YTHDC2/FGFR2/RHOA/SIRT2/ASNS/CDC42/SPAG5/NDC80/ATRX/NSFL1C/ANAPC5/BIRC5/CCNK/CDC6/ABL1/CDC7/PDGFB/APEX1/CDC25B/RAB11A/EZH2/RPS6KB1/ZPR1/CCND1/FBXO5/SMOC2/CCND3/MACROH2A1/PDGFRB/SMC4/KAT2B/WNT5A/HES1/TTL/IL1A/PKD2/SLF2/IL1B/BECN1/HSPA2/SOX15/RARA/CCNB1/PSRC1/RPS15A/CDCA8/SRPK2/IL10/NUMA1/RDX/NUSAP1/KIF23/EGF/BRCA2/RB1/CUL4A/IGF1R/CYP1A1/APP/DTL/DYRK3/PKP4/EGFR/NCAPG2/BCL2L11/PRKCA/ADAMTS1/LSM11/CUL4B/CXCR5/DBF4B/TAL1/WNT4/TERT/RRM1/CDK1/PRKCE/RHNO1/RRM2/HCFC1/KAT5/CKS1B/STAT5B/FOSL1/CDK5R1/CD28/AURKB/RCC2/CALR/PTPN11/MAPK15/NPM1/PLCB1/CHEK2/CDK10/PBX1/PLSCR1/SRC/TFDP1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ZBED6/CCPG1/PAGR1/LRP6 118
GO:0043370 regulation of CD4-positive, alpha-beta T cell differentiation 32/3662 52/15509 5.75513e-09 1.14695e-07 6.89758e-08 RUNX3/FOXP3/CBFB/TBX21/IL4R/IL12RB1/SMAD7/JAK3/GATA3/IFNG/IL12B/IL4/BCL6/CD86/MYB/CD80/RARA/HLX/IRF4/IL2RG/IL18/RUNX1/LGALS9/CCL19/KLHL25/SOCS1/HMGB1/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 32
GO:0043542 endothelial cell migration 88/3662 213/15509 6.38492e-09 1.26839e-07 7.62786e-08 DCN/SNAI2/GRN/FLT4/ATP2B4/SP100/RHOA/FGFR1/PXN/APOH/ANGPT2/ABL1/PDGFB/MYH9/CD40/GPI/PRKD2/TGFB1/PIK3CG/PTN/MET/HSPB1/TGFBR1/GATA3/LPXN/SMOC2/WNT5A/GADD45A/NRP2/TEK/PTK2B/NR4A1/ID1/RRAS/STAT5A/KDR/APOE/LOXL2/GLUL/CCN3/THBS1/CYP1B1/FGF2/EGF/EPHA2/RAB13/RHOB/SLIT2/PLK2/NOTCH1/ITGB1/VEGFC/PRKCA/CXCL13/STC1/EMC10/NOS3/EFNA1/PTK2/SCG2/SVBP/CALR/ADGRB1/PTP4A3/CIB1/CLN3/HMGB1/DPP4/CSNK2B/TNF/TMSB4X/TNF/ZNF580/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PDCD6/ITGB3/AKT3/GPI/PTEN 88
GO:0050798 activated T cell proliferation 29/3662 45/15509 6.47472e-09 1.28212e-07 7.71043e-08 IGF1/BTN3A1/FOXP3/IL12RB1/ABL1/PYCARD/IL27RA/CLC/JAK3/IL12B/IGFBP2/ARG1/GPAM/TNFSF9/EPO/IL2RA/IL18/ICOSLG/CASP3/FADD/LGALS9/STAT5B/LILRB4/HMGB1/PDCD1LG2/CD24/LILRB4/LILRB4/LILRB4 29
GO:0048017 inositol lipid-mediated signaling 76/3662 176/15509 6.87853e-09 1.35774e-07 8.16523e-08 WNT16/DCN/IGF1/HGF/GAB2/PREX2/ERBB3/SIRT2/FGFR1/OSM/PIK3IP1/PDGFB/PPP1R16B/FLT1/TSC2/PIK3CG/GATA3/UNC5B/CSF3/RPS6KB1/C1QBP/PPARD/PDGFRB/FN1/CD160/TEK/CAT/FLT3/BECN1/KDR/PDGFRA/SERPINE2/PLCB2/PLCE1/FGF2/EGF/IGF1R/KCNH1/PDGFC/PIK3R1/EGFR/OGT/NTRK2/PLCH2/IL18/KIT/PLCD3/GPER1/PTK2/PTAFR/SEMA3E/SELP/LEP/CD28/F2/F2R/CSF1R/PLCB1/ROR1/ZFP36L1/PRR5/PLCD1/SRC/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/CCL5/CCL5/PTEN 76
GO:0014065 phosphatidylinositol 3-kinase signaling 64/3662 140/15509 7.19954e-09 1.4166e-07 8.51916e-08 WNT16/DCN/IGF1/HGF/PREX2/ERBB3/SIRT2/FGFR1/OSM/PIK3IP1/PDGFB/PPP1R16B/FLT1/TSC2/PIK3CG/GATA3/UNC5B/CSF3/C1QBP/PPARD/PDGFRB/FN1/CD160/TEK/CAT/FLT3/BECN1/KDR/PDGFRA/SERPINE2/FGF2/EGF/IGF1R/PDGFC/PIK3R1/EGFR/NTRK2/IL18/KIT/GPER1/PTK2/SEMA3E/SELP/LEP/CD28/F2/F2R/ROR1/ZFP36L1/PRR5/SRC/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/CCL5/CCL5/PTEN 64
GO:0009636 response to toxic substance 91/3662 223/15509 7.35413e-09 1.44243e-07 8.67454e-08 KDM1A/MPO/PON1/CPS1/BAK1/CDH1/RAD51/ABCB1/BAX/SLC7A8/PTGS1/DHRS2/BMP7/GSR/AHR/RPS6KB1/SRSF9/PDGFRB/SDC1/PARK7/KDM5B/PRDX1/PRDX6/MTARC2/ARG1/ABCG2/DNMT3A/EPHX2/UBIAD1/CAT/APOE/PXDN/ASS1/SESN2/GSTM1/CD36/CYP1B1/CYP1A1/SOD1/SLC47A1/EPHX1/ALAD/GSTO1/FANCC/ADAMTS13/INHBB/FABP1/ALB/NOS3/TP53INP1/GPX4/NXN/PRDX2/CDK1/FOS/MGMT/CNP/PDZK1/TYMS/NQO1/SNN/PRKN/SLC22A5/MBP/TXNRD1/SELENOT/TNF/TNF/GPX3/LTC4S/HBE1/HBD/TNF/TNF/TNF/TNF/TNF/TNF/HBB/HP/SRXN1/CCL5/CCL5/CCL4/CCL4/NEFL/TPO/GSTT1/CCL4/ADAMTS13/LTC4S 91
GO:0032642 regulation of chemokine production 49/3662 97/15509 7.43636e-09 1.45396e-07 8.74386e-08 SNAI2/CD74/EIF2AK2/IL4R/ARG2/MAVS/MEFV/PYCARD/IL7/IFNG/IL17A/WNT5A/EGR1/IL1B/IL6/IL10/TLR4/APP/EPHA2/IL18/IL6R/TLR3/SYK/NOD2/LGALS9/LPL/ADIPOQ/CSF1R/SIGIRR/LILRB4/CARD9/HMGB1/TLR7/ELANE/MBP/TNF/TNF/ACKR1/TNF/TNF/TNF/TNF/TNF/TNF/LILRB4/MIF/ELANE/LILRB4/LILRB4 49
GO:0045620 negative regulation of lymphocyte differentiation 31/3662 50/15509 7.6927e-09 1.49915e-07 9.01565e-08 CD74/RUNX3/HMGB3/FOXP3/CBFB/TBX21/IL4R/SMAD7/SFRP1/JAK3/MDK/IL4/BCL6/ID2/INHBA/FOXJ1/HLX/RUNX1/CTLA4/SHH/PRDX2/RAG2/PTPN2/SOCS1/LILRB4/HMGB1/NRARP/CR1/LILRB4/LILRB4/LILRB4 31
GO:0050830 defense response to Gram-positive bacterium 55/3662 114/15509 7.71588e-09 1.49915e-07 9.01565e-08 SEH1L/P2RX7/LYZ/CTSG/ACP5/PYCARD/IL27RA/NOD1/TNFSF8/IL17A/H2BC11/IL1B/RNASE1/CD36/IL6/EPHA2/IL18/MR1/MBL2/NOD2/H2BC21/CARD9/RPL39/TNF/HLA-E/PPP1R11/TNF/HLA-E/HLA-A/HLA-A/LTA/TNF/HLA-A/HLA-A/HLA-E/LTA/HLA-A/TNF/TNF/TNF/HLA-A/HLA-E/TNF/HLA-E/LTA/LTA/HLA-A/TNF/HLA-E/HLA-A/HLA-E/LTA/RNASE4/H2BC6/H2BC7 55
GO:0030218 erythrocyte differentiation 56/3662 117/15509 8.13151e-09 1.57497e-07 9.47161e-08 SLC4A1/KMT2E/UFL1/ALAS1/KCNQ1/HIPK2/SPI1/ACIN1/GATA1/ERCC2/KLF1/JAK3/HOXA5/GATA3/SLC11A2/SH2B3/MAPK14/RHAG/HSPA9/SMAD5/BCL6/STAT1/ID2/EPAS1/MYB/FOXO3/PTBP3/INHBA/THRA/PRMT1/ZFP36/EPO/ABCB10/RB1/ARNT/DYRK3/NCAPG2/KIT/ALAS2/DMTN/TAL1/BAP1/CASP3/SFXN1/EPB42/INPP5D/AHSP/STAT5B/PTPN2/ZFP36L1/CDIN1/L3MBTL3/MAFB/PRKDC/B2M/INPP5D 56
GO:0010506 regulation of autophagy 114/3662 298/15509 8.56552e-09 1.65387e-07 9.94606e-08 BAD/OSBPL7/DCN/UFL1/HGF/RRAGD/ATP6V0A1/CLEC16A/PHF23/CTSA/KDM4A/ROCK1/TBC1D25/SIRT2/VPS35/CSNK2A2/PRKACA/MID2/GSK3B/ZMPSTE24/ATG16L1/DNM1L/ABL1/SH3GLB1/EEF1A2/CHMP4B/NPRL3/TSC2/MEFV/PYCARD/SNRNP70/GSK3A/MET/NOD1/HSPB1/TRIM14/MAPK8/EIF4G2/IFNG/IL4/SNX4/ATP6V1A/TMEM59/PARK7/ELAPOR1/LEPR/ATP6V0B/FOXO3/CAPNS1/BECN1/ATG14/KDR/SESN2/TRIM5/TRIM22/PRKAA1/TBC1D14/PTPN22/IL10/ATP6V1G1/TRIM65/ABL2/PLK2/TLK2/ATP6V1B2/C9orf72/SESN3/SOGA1/FOXO1/ITPR1/BAG3/HSPB8/BCL2L11/UCHL1/ATP6V1C1/DRAM2/EEF1A1/TAB3/FYCO1/CASP3/CDK5/TP53INP1/DEPP1/GOLGA2/NOD2/TRIM68/ADRB2/TRIM8/ORMDL3/SNX32/KAT5/GPR137/LEP/DDIT3/ATG13/TMEM39A/CDK5R1/WDR6/ERN1/MAPK15/EXOC7/PRKN/CLN3/HMGB1/DAPK1/SVIP/MTOR/DCAF12/RNF5/TRIM13/MAGEA3/IKBKG/PIP4K2B/PRKACA 114
GO:0090218 positive regulation of lipid kinase activity 24/3662 34/15509 8.71583e-09 1.67766e-07 1.00892e-07 FGFR3/CDC42/EPHA8/PDGFB/EEF1A2/FLT1/TGFB1/CD81/PDGFRB/TEK/PTK2B/FLT3/CCR7/ATG14/PDGFRA/CCL21/FGF2/KIT/NOD2/PTK2/CCL19/CD19/F2/SRC 24
GO:0045862 positive regulation of proteolysis 128/3662 345/15509 9.50036e-09 1.82301e-07 1.09633e-07 BAD/CASP10/OSBPL7/PSMC4/RNF14/FAS/TNFRSF1B/BAK1/GRN/HERPUD1/CYFIP2/NGFR/ATXN3/RHOA/PSME4/SIRT2/FBXW11/PICALM/MKRN2/SIRT6/FBLN1/GSK3B/BAX/PSMC5/PSME1/HECTD1/BAG6/MYH9/PSMC6/SMAD7/AXIN1/MEFV/PYCARD/SGTA/PDCD5/GSK3A/NOD1/CASP2/PLGRKT/DVL1/SH3D19/CTSC/IFNG/USP5/PERP/FN1/HSPE1/CDC20/FASLG/CLU/PTK2B/TNFSF10/SEMG1/IL1B/CBFA2T3/APOE/ADRM1/PSME3/HSPBP1/AKIRIN2/TANK/ANP32B/MTCH1/BCL2L10/EGF/FURIN/CSNK1D/PMAIP1/APP/CCN1/ARL6IP5/OGT/GSN/RNF144A/BCL2L11/NODAL/MMP14/PSMC2/DISC1/RCHY1/MELTF/GPER1/SYK/VCP/PSMC3/BTRC/FADD/ADAM9/LGALS9/PRELID1/EFNA1/PTK2/ANTXR1/EIF2AK3/AURKAIP1/GRIN1/MAGEF1/SVBP/F2R/RGMA/ANXA2/CNTN2/PRKN/CARD9/HMGB1/DAPK1/SRC/MAP3K5/MBP/CR1/BAG6/TNF/PSENEN/TNF/FIS1/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/CEBPA/PDCD6/PTEN 128
GO:0016571 histone methylation 65/3662 144/15509 1.02554e-08 1.96183e-07 1.17981e-07 NFYA/KDM1A/KMT2E/PAF1/AASS/ARID4B/PRDM1/KDM4A/NFYC/ATRX/MECOM/DNMT3B/SMARCB1/SETD6/DOT1L/FBL/EZH2/GATA3/EZH1/NSD2/HCFC2/MACROH2A1/KDM3A/ASH1L/MYB/PHF19/H1-3/PRMT1/ASH2L/PRDM12/DNMT1/PRMT7/MEN1/TET1/SKIC8/SMAD4/CARM1/BOD1/OGT/NSD3/SMARCA5/RNF20/PRMT2/LMNA/GFI1/PYGO2/NSD1/NNMT/SETD5/H1-4/COPRS/HCFC1/TRMT112/SUZ12/SETD2/SETD3/KMT5A/TET3/H1-2/PAX5/WDR5/WDR5B/NCOA6/SMARCB1/PAGR1 65
GO:1904645 response to amyloid-beta 32/3662 53/15509 1.12384e-08 2.14325e-07 1.28891e-07 IGF1/NGFR/FCGR2B/GSK3B/MMP2/ICAM1/MMP9/ABCC1/ITGA4/FOXO3/LRP1/BCL2L2/EPHB2/CD36/TLR4/IGF1R/APP/PARP1/GJA1/BCL2L11/VCAM1/CDK5/ADRB2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ABCC1 32
GO:2000112 regulation of cellular macromolecule biosynthetic process 151/3662 424/15509 1.14158e-08 2.17041e-07 1.30525e-07 UPF1/IGF1/EIF2AK2/PUM2/SOAT1/EIF4B/ELAVL1/PKM/RHOA/ROCK1/ELP1/MLH1/MKNK1/DDX1/BZW1/GSK3B/TUT7/TMED2/PPP1R15A/MAPKAPK5/GCN1/AARS1/AGO1/CIRBP/MKNK2/GZMB/PCIF1/GATA1/JAK3/GSK3A/MTPN/HSPB1/EIF3B/EIF4H/FKTN/EXOSC3/LARP4B/CASC3/RPS6KB1/C1QBP/DPH1/EIF4G2/DDX6/HBEGF/XRN1/EIF1B/NCL/PASK/DPH5/FOXO3/EIF2B2/PPP1R3C/MTRF1/PAIP2/SERP1/PTK2B/TARDBP/SOX4/CNOT1/NECAB3/CCR7/PRMT1/TRAP1/DYRK2/ZFP36/SESN2/RARA/PER2/ELP2/ABCB10/NIBAN1/ITM2C/EIF4E2/IL6/BZW2/IREB2/NCBP1/CCL21/THBS1/CYP1B1/LARP1B/TARBP2/TOB1/EIF4A3/GRB7/APP/POLR2D/CNOT9/SLC25A37/EIF3H/EIF4EBP2/TCF7L2/MTG1/CDC123/GUF1/ZFP36L2/RMND1/USP16/EIF4A2/CNOT11/PPP1R15B/BTG2/ZNF385A/RPL26/RPUSD4/GOLGA2/PTAFR/ELP5/PA2G4/ENC1/EIF2AK3/PAIP1/CCL19/DCP2/EIF1/PDE12/ATG13/TYMS/SHMT1/CD28/CALR/TRNAU1AP/NPM1/PLCB1/KLHL25/EIF3C/ZFP36L1/YTHDF3/SECISBP2/DAPK1/SLC2A10/SVIP/MTOR/SELENOT/GIGYF2/TNF/SARNP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/PRKDC/LSM14A/RBM8A/CCL5/CCL5/AATF 151
GO:0032602 chemokine production 49/3662 98/15509 1.14825e-08 2.17642e-07 1.30886e-07 SNAI2/CD74/EIF2AK2/IL4R/ARG2/MAVS/MEFV/PYCARD/IL7/IFNG/IL17A/WNT5A/EGR1/IL1B/IL6/IL10/TLR4/APP/EPHA2/IL18/IL6R/TLR3/SYK/NOD2/LGALS9/LPL/ADIPOQ/CSF1R/SIGIRR/LILRB4/CARD9/HMGB1/TLR7/ELANE/MBP/TNF/TNF/ACKR1/TNF/TNF/TNF/TNF/TNF/TNF/LILRB4/MIF/ELANE/LILRB4/LILRB4 49
GO:0002517 T cell tolerance induction 22/3662 30/15509 1.18141e-08 2.23243e-07 1.34254e-07 FOXP3/CLC/IL2RA/TGFBR2/LILRB4/HLA-G/HLA-B/HLA-G/HLA-B/HLA-B/HLA-B/HLA-G/HLA-B/HLA-G/HLA-G/HLA-G/HLA-G/LILRB4/HLA-G/LILRB4/LILRB4/ITCH 22
GO:0042063 gliogenesis 111/3662 290/15509 1.29497e-08 2.43959e-07 1.46713e-07 TMEM98/PAFAH1B1/CD9/UFL1/CNTN1/TNFRSF1B/GRN/HEXB/SYNE2/NTN1/ERBB3/KDM4A/RHOA/SIRT2/WDR1/TP73/LRP2/ABL1/CSK/ARHGEF10/ERCC2/TGFB1/PTN/EZH2/ZMIZ1/CCL2/CNTNAP1/AREG/MDK/IFNG/HES1/ID2/HDAC1/LEPR/EIF2B2/CLU/PTK2B/CXCR4/EGR2/LRP1/SOX4/MYRF/IL1B/NKX2-2/BMP2/NR1D1/RRAS/LIF/WASF3/KRAS/TSPAN2/SERPINE2/IL6/NKX2-1/TLR4/FGF2/RB1/SOD1/APP/DUSP10/TNFRSF21/NTRK2/NOTCH1/PARD3/VEGFC/MMP14/SKI/CUL4B/B4GALT5/NDUFS2/MXRA8/DISC1/SLC25A46/SHH/CDK5/CX3CR1/CDK1/CDH2/LAMB2/DAG1/CSPG4/CNP/CDK5R1/KCNJ10/PLEC/SUZ12/PTPN11/F2/PLAG1/CSF1R/NOG/CNTN2/CSF1/POU3F2/ROR1/NF2/MTOR/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/PTEN 111
GO:0051348 negative regulation of transferase activity 95/3662 238/15509 1.30265e-08 2.44661e-07 1.47135e-07 MVP/PARP3/IPO5/HYAL2/PTPRC/GSK3B/RTRAF/ABL1/GADD45B/PIK3IP1/GSKIP/BMP7/SMAD7/TSC2/PYCARD/CSK/SFRP1/GSK3A/HSPB1/DVL1/CHORDC1/CORO1C/SH2B3/IFNG/FBXO5/MACROH2A1/KAT2B/PRKAR2A/PARK7/GADD45A/CDC20/TNFAIP3/PKN1/CDKN1A/IL1B/BMP2/ZFP36/POT1/AJUBA/CDKN1C/APOE/CEP85/VPS25/EPHB2/MEN1/PTPN22/APC/SPRY2/SORL1/TARBP2/RB1/WARS1/PIF1/DUSP10/NCAPG2/HHEX/UCHL1/GNAQ/EIF4A2/CAMK2N1/PRKCD/DUSP7/CASP3/PKIG/RGS14/ORMDL3/PTPN2/CHMP6/PLEC/TAF7/PAK2/ADIPOQ/NPM1/SLC8A1/PRKN/NF2/LILRB4/HEXIM1/SPRY4/PPIA/SRC/AKT1S1/IPO7/DBNDD2/CEBPA/TEN1/PTPRC/CDKN1C/LILRB4/PIP4K2B/LILRB4/LILRB4/LRP6/PTEN/CHORDC1 95
GO:0001818 negative regulation of cytokine production 106/3662 274/15509 1.41658e-08 2.65256e-07 1.5952e-07 BTK/HFE/TYROBP/LTF/IGF1/SLC11A1/HGF/SARS1/FOXP3/CDH3/NAV3/FCGR2B/TBX21/ARG2/PTPRC/PIBF1/HSP90AB1/SMAD7/TLR8/ACP5/N4BP1/MEFV/PYCARD/CSK/LILRB1/IL27RA/TGFB1/CD33/JAK3/EZH2/GATA3/C1QBP/IFNG/IL12B/IL4/BCL6/FN1/TNFAIP3/ARG1/INHBA/SRGN/CCR7/ZFP36/TWSG1/FOXJ1/NDFIP1/RARA/SYT11/EPHB2/SFTPD/PTPN22/IL6/IL10/TLR4/THBS1/PPM1B/FURIN/ARRB2/EPHA2/TNFRSF21/MERTK/CD96/NLRX1/INHBB/NDRG2/NOD2/CX3CR1/INPP5D/LGALS9/KAT5/DDIT3/BANF1/F2/ADIPOQ/TRAIP/SIGIRR/PRG2/LILRB4/HMGB1/SLC2A10/ELANE/PDCD1LG2/CR1/TNF/PPP1R11/TMSB4X/TNF/TNF/TNF/TNF/TNF/ORM1/TNF/TNF/PTPRC/CD24/LILRB1/LILRB4/LILRB1/LILRB1/ELANE/LILRB1/LILRB4/LILRB4/INPP5D/ITCH 106
GO:0051897 positive regulation of protein kinase B signaling 52/3662 107/15509 1.43584e-08 2.68052e-07 1.61202e-07 IGF1/F7/FGFR1/LRP2/NOX4/HSP90AB1/OSM/RASD2/TGFB1/PIK3CG/MET/TGFBR1/ENG/GATA3/CSF3/C1QBP/HBEGF/PARK7/TEK/IAPP/CCR7/GDF15/CHI3L1/SPRY2/CCL21/THBS1/FGF2/EGF/IGF1R/ARRB2/TPBG/EGFR/TCF7L2/ITGB1/IL18/RICTOR/CX3CR1/PTK2/CCL19/LEP/CD28/AKR1C3/SRC/TNF/TNF/CPNE1/TNF/TNF/TNF/TNF/TNF/TNF 52
GO:0002675 positive regulation of acute inflammatory response 25/3662 37/15509 1.73022e-08 3.22038e-07 1.93668e-07 BTK/OSM/PIK3CG/PARK7/IL1B/C3/CCR7/IL6/TNFRSF11A/ZP3/TNF/HLA-E/TNF/HLA-E/TNF/HLA-E/TNF/TNF/TNF/HLA-E/TNF/HLA-E/TNF/HLA-E/HLA-E 25
GO:0016570 histone modification 147/3662 413/15509 1.8588e-08 3.44935e-07 2.07438e-07 NFYA/KDM1A/KMT2E/PAF1/AASS/MED24/BAZ1B/UFL1/SNAI2/FOXP3/RAD51/ARID4B/HPF1/PRDM1/KDM4A/NFYC/SPI1/SIRT2/MBD3/ACTB/SIRT6/UBE2A/ZMPSTE24/ATRX/MECOM/ATXN7L3/DNMT3B/KDM2B/BRPF3/SMARCB1/RBBP7/JADE3/SETD6/DOT1L/FBL/PRKD2/EZH2/GATA3/MAPK8/EZH1/NSD2/NAA40/CHD4/HCFC2/PHC1/ZNF451/SKP1/MACROH2A1/BCL6/KAT2B/SF3B1/KDM3A/PARK7/HDAC1/ASH1L/KDM5B/DR1/MYB/PHF19/KDM3B/NAA50/MORF4L2/H1-3/DEK/PRMT1/YEATS4/LIF/ASH2L/PRDM12/DNMT1/PER2/MYBBP1A/WBP2/PRMT7/MEN1/DDB2/TAF5L/EPC2/IRF4/TET1/BRCA2/SKIC8/SMAD4/CARM1/BOD1/NCAPG2/OGT/NSD3/KAT14/MBIP/SMARCA5/RNF20/USP16/BRPF1/SKI/CUL4B/ELK4/CTBP1/PRMT2/LMNA/TAF6L/RBBP4/MYSM1/GFI1/PYGO2/RYBP/BAP1/NSD1/BRD7/RAG1/NNMT/GATAD2A/SETD5/H1-4/RIOX1/RIOX2/TADA3/JMJD1C/COPRS/HCFC1/KAT5/TRMT112/KDM2A/MSL2/SUZ12/TAF7/AURKB/PCGF5/SETD2/SETD3/KMT5A/MUC1/USP7/TET3/H1-2/NOC2L/PAX5/WDR5/TRRAP/WDR5B/PHF2/NCOA6/SMARCB1/UHRF1/TADA2A/PCGF2/PAGR1 147
GO:1901653 cellular response to peptide 124/3662 335/15509 1.88915e-08 3.49521e-07 2.10196e-07 IGF1/CPS1/CASR/CYBA/NGFR/PKM/ROCK1/FCGR2B/ACTN2/GSK3B/RAB10/CHMP5/PXN/ICAM1/CDC6/XBP1/RANGAP1/APEX1/PCK2/TSC2/ABCC1/CSK/PLAT/SLC39A14/KLF1/JAK3/GSK3A/NOD1/RPS6KB1/CCND3/KAT2B/NCL/ITGA4/STAT1/ARG1/FOXO3/NR4A3/CRHR1/INHBA/NR4A1/LRP1/NCOA5/IL1B/MAX/ID1/STAT5A/BCL2L2/GDF15/ASS1/PRKAA1/LPIN3/EPHB2/MEN1/PTPN22/APC/CD36/TLR4/SORL1/CYP1B1/RB1/IGF1R/APP/RAB13/PKLR/PARP1/CCNA2/PIK3R1/OGT/EIF4EBP2/SESN3/SOGA1/FOXO1/POU4F2/GJA1/BCL2L11/NR4A2/APPL1/ADIPOR1/SHC1/JAK1/SCNN1D/VCAM1/INHBB/PRKCD/GPER1/CDK5/ZNF592/SLC27A4/NOD2/AHCYL1/ADRB2/PTK2/FOS/SLC25A33/KLF11/RELA/ESRRA/STAT5B/LEP/PTPN2/LPL/GRB2/ERFE/PTPN11/ADIPOQ/PLCB1/FOXO4/SOCS1/ZFP36L1/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/ITGB3/GH1/PKLR/PIP4K2B/ABCC1 124
GO:0043666 regulation of phosphoprotein phosphatase activity 36/3662 64/15509 1.93378e-08 3.56714e-07 2.14521e-07 ROCK1/PTPRC/GSK3B/PPP1R15A/FKBP1A/HSP90AB1/PPP6R2/CD33/PDGFRB/PTPA/MASTL/CRY2/STYXL1/CALM2/BOD1/GNA12/PPP1R15B/CALM3/PPP1R2/MAGI2/MTOR/CSNK2B/TNF/PPP1R11/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PTPRC 36
GO:0001936 regulation of endothelial cell proliferation 61/3662 134/15509 1.95529e-08 3.58778e-07 2.15763e-07 FLT4/CYBA/NGFR/TIE1/SIRT6/FGFR1/APOH/PDGFB/PPP1R16B/FLT1/PRKD2/TGFBR1/CXCL12/CCL2/MDK/IL12B/WNT5A/ITGA4/STAT1/PDCL3/NRP2/ARG1/PGF/TEK/NR4A1/BMP2/STAT5A/KDR/ALDH1A2/APOE/IL10/THBS1/FGF2/EGF/ARNT/VEGFC/BMP6/PRKCA/EMC10/AIMP1/AGGF1/SCG2/CCL11/EGFL7/LEP/JUN/HMGB1/NRARP/TNF/TNF/ZNF580/NRAS/TNF/TNF/TNF/TNF/TNF/TNF/PDCD6/ITGB3/AKT3 61
GO:0031960 response to corticosteroid 68/3662 155/15509 1.95655e-08 3.58778e-07 2.15763e-07 BAD/CPS1/CYBA/PTPRU/RHOA/PCK2/PLAT/GSK3A/ENG/RPS6KB1/AREG/CCND1/MDK/IGFBP2/SDC1/ARG1/FOXO3/KLF9/FLT3/FOSB/ZFP36/CDO1/EPO/ASS1/IL6/IL10/IL1RN/CYP1B1/IGF1R/PARP1/SLIT2/ALAD/NOTCH1/ZFP36L2/BCL2L11/BMP6/STC1/CALM3/SCNN1D/CASP3/GPER1/CYBB/ABCA3/DDIT4/ADAM9/PTAFR/FOS/FOSL1/A2M/TYMS/SSTR2/ADIPOQ/PAPPA/SLIT3/ZFP36L1/UBE2L3/WNT7B/AKR1C3/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEFL 68
GO:0072594 establishment of protein localization to organelle 143/3662 400/15509 2.11208e-08 3.86155e-07 2.32227e-07 AGK/POLA2/TOMM34/CDH1/HSPA5/HERPUD1/SEC61A1/TNPO3/AP3D1/IPO5/SEC61A2/ELAVL1/HYAL2/CSNK2A2/LMAN1/SIRT6/TNPO1/RAB10/IPO11/BAX/MAVS/NUP50/BAG6/HSP90AB1/SH3GLB1/TIMM13/RNF215/SAMM50/GZMB/TIMM9/NFKBIA/FERMT1/CHMP4B/NXT2/UBL4A/KPNA3/MON1B/TSC2/RAB11A/SGTA/PDCD5/TGFB1/TNPO2/GSK3A/MAPK8/RANGRF/GRPEL1/ZPR1/HSPA8/IFNG/MAN1A1/MAPK14/PEX7/MACROH2A1/KPNA1/SPCS1/MFN2/TNFAIP3/CLU/TARDBP/CRY2/CSE1L/CDKN1A/NUP153/NUP85/BECN1/ATG14/RAC2/POT1/CD68/DKC1/HACL1/VPS25/TIMM10B/PRKAA1/WBP2/NXT1/AP3B1/IPO8/CD36/MDFIC/AKIRIN2/CCT7/VPS36/NMT1/SORL1/NABP2/BRCA2/SRP14/SAE1/SRPRB/PIK3R1/NOTCH1/IMMP1L/TIMM8B/BAG3/RANBP2/HEATR3/APPL1/ZFAND2B/CALM3/LMNA/PEX19/BAP1/PRKCD/TERT/SHH/SYK/CCT2/CHP2/SRP68/PKIG/MFF/CDK1/TOMM20/LEP/DDIT3/ATG13/TOMM5/PTTG1IP/AP3M1/PRKN/HGS/UBE2L3/IPO4/UBL5/IPO9/HSPA1L/BAG6/IPO7/HSPA1L/FIS1/HSPA1L/BAG6/BAG6/BAG6/HSPA1L/BAG6/HSPA1L/TIMM23/TXNIP/SQSTM1/IPO4 143
GO:0002274 myeloid leukocyte activation 90/3662 224/15509 2.15677e-08 3.93167e-07 2.36444e-07 KMT2E/BTK/TYROBP/SLC11A1/CD74/GRN/GAB2/C12orf4/KARS1/SPI1/HYAL2/FCGR2B/STXBP2/IL4R/PTPRC/LAT2/CTSG/DHRS2/GATA1/PYCARD/CD33/HAMP/PIK3CG/CTSC/IFNG/IL4/WNT5A/SNX4/FN1/VAMP8/NR4A3/CLU/NR1D1/RAC2/NECTIN2/SYT11/NOTCH2/IL6/IL10/STXBP1/TLR4/IRF4/THBS1/APP/CPLX2/IL18/KIT/ITGB2/TGFBR2/PRKCD/TLR3/CSF2/SYK/RBPJ/CX3CR1/RHOH/ADAM9/TNIP2/LGALS9/PTAFR/CXCL8/ITGAM/PRKCE/JUN/CXCR2/CSF1/LILRB4/PLSCR1/CNR2/HMGB1/TRPV1/SHPK/TNF/CD177/CRLF2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/PTPRC/CCL5/CCL5/LILRB4/MIF/LILRB4/LILRB4 90
GO:0006469 negative regulation of protein kinase activity 77/3662 183/15509 2.16907e-08 3.94249e-07 2.37095e-07 MVP/IPO5/HYAL2/PTPRC/RTRAF/ABL1/GADD45B/GSKIP/BMP7/TSC2/PYCARD/SFRP1/HSPB1/DVL1/CHORDC1/CORO1C/SH2B3/IFNG/MACROH2A1/KAT2B/PRKAR2A/PARK7/GADD45A/TNFAIP3/PKN1/CDKN1A/IL1B/BMP2/CDKN1C/APOE/CEP85/VPS25/EPHB2/MEN1/PTPN22/APC/SPRY2/SORL1/TARBP2/RB1/WARS1/DUSP10/NCAPG2/HHEX/UCHL1/GNAQ/CAMK2N1/PRKCD/DUSP7/CASP3/PKIG/RGS14/PTPN2/CHMP6/PLEC/TAF7/PAK2/ADIPOQ/NPM1/SLC8A1/NF2/LILRB4/HEXIM1/SPRY4/PPIA/AKT1S1/IPO7/DBNDD2/CEBPA/PTPRC/CDKN1C/LILRB4/LILRB4/LILRB4/LRP6/PTEN/CHORDC1 77
GO:0042542 response to hydrogen peroxide 53/3662 111/15509 2.24823e-08 4.07443e-07 2.45029e-07 BAD/HGF/GLRX2/BAK1/MMP2/ABL1/APEX1/MET/EZH2/PPIF/AREG/CRYAB/PDGFRB/STAT1/SDC1/PARK7/TNFAIP3/ARG1/FOXO3/NR4A3/PTK2B/CAT/BECN1/TRAP1/PRKAA1/IL6/IL10/IL18BP/CYP1B1/SOD1/RHOB/PPP1R15B/CAPN2/FABP1/PRKCD/CASP3/FXN/ADAM9/CDK1/RELA/FOSL1/ERN1/NQO1/SLC8A1/SRC/MAP3K5/ND6/ZNF277/ZNF580/HBB/HP/TXNIP/PCGF2 53
GO:0035304 regulation of protein dephosphorylation 47/3662 94/15509 2.2725e-08 4.1064e-07 2.46952e-07 PTBP1/ROCK1/PTPRC/GSK3B/PPP1R15A/FKBP1A/HSP90AB1/PPP6R2/PPP1R16B/TGFB1/CD33/PPP2R5D/PDGFRB/PTPA/MASTL/CRY2/PIN1/STYXL1/ENSA/CALM2/BOD1/GNA12/SPPL3/PPP1R15B/CALM3/PRKCD/NSMF/ANKLE2/PPP1R2/MAGI2/PPIA/MTOR/CSNK2B/TNF/PPP1R11/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PTPRC 47
GO:0046006 regulation of activated T cell proliferation 27/3662 42/15509 2.34024e-08 4.20429e-07 2.52838e-07 IGF1/FOXP3/IL12RB1/PYCARD/IL27RA/CLC/JAK3/IL12B/IGFBP2/ARG1/GPAM/TNFSF9/EPO/IL2RA/IL18/ICOSLG/CASP3/FADD/LGALS9/STAT5B/LILRB4/HMGB1/PDCD1LG2/CD24/LILRB4/LILRB4/LILRB4 27
GO:1904707 positive regulation of vascular associated smooth muscle cell proliferation 27/3662 42/15509 2.34024e-08 4.20429e-07 2.52838e-07 IGF1/MMP2/PDGFB/MMP9/BMPR1A/MFN2/NR4A3/DNMT1/IL10/FGF2/GJA1/ADAMTS1/LDLRAP1/TERT/FRS2/JUN/ERN1/SRC/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 27
GO:0043254 regulation of protein-containing complex assembly 134/3662 370/15509 2.40101e-08 4.301e-07 2.58654e-07 DHX33/SCIN/BAK1/HSPA5/FNIP2/CYFIP2/EIF2AK2/RNF4/RHOA/NAV3/SIRT2/VPS35/SPTB/CDC42/ADD2/GSK3B/BAX/ADD1/ESR1/ABL1/SH3GLB1/TFIP11/PSMC6/TCL1A/FERMT1/HCK/RIOK3/COTL1/MEFV/PIEZO1/PYCARD/MED25/TGFB1/MTPN/MET/DKK1/CSF3/RANGRF/CRYAB/HSPA8/ARPC3/IFNG/IL5/DBN1/HES1/PARK7/CAPZA1/STMN1/SLF2/CLU/PTK2B/IAPP/EML2/THRA/CCR7/CDC42EP1/AJUBA/APOE/ARPC1B/PSRC1/HRK/CD36/LCP1/DBNL/STXBP1/TLR4/CCL21/ATAT1/NUMA1/SORL1/RDX/SMAD6/RB1/SLAIN1/WARS1/BBS4/TBCD/PARP1/SLIT2/ARHGAP18/MSN/GSN/CDC42EP2/BCL2L11/GBP5/CXCL13/DMTN/SPTBN4/ALOX15/TAL1/ARPC5/H3-3A/CDC42EP3/SPTA1/PRKCD/RICTOR/ANKRA2/CSF2/SYK/VCP/ABCA3/PRKCE/CCL11/HCFC1/SPTBN2/SELP/CDK5R1/FLII/GRB2/CTNNBIP1/PTPN11/BBS10/MAPK15/INPP5J/DRG1/HMGB1/MMP1/SRC/SPTAN1/SVIP/MTOR/IQANK1/TNF/TMSB4X/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ARPC1A/TWF2/BRK1 134
GO:0042060 wound healing 148/3662 418/15509 2.45189e-08 4.37948e-07 2.63374e-07 SLC4A1/ADIPOR2/CD9/IGF1/SLC11A1/CD44/F7/CDH3/ERBB3/MYLK/FGFR2/RHOA/LMAN1/ACTB/MCAM/FBLN1/CD59/CHMP5/APOH/DSP/XBP1/PDGFB/MYH9/CTSG/PROCR/CD40/FERMT1/CHMP4B/GATA1/CD40LG/DGKH/PLAT/TGFB1/TFPI2/PIK3CG/HSPB1/SERPINE1/TGFBR1/ACTA2/HGFAC/VWF/WNT5B/SH2B3/PPARD/MAPK14/SMOC2/HBEGF/PDGFRB/WNT5A/IL1A/FN1/SDC1/MPL/SERPINC1/TNFAIP3/PPL/GNA13/CXCR4/F13A1/CDKN1A/AHNAK/KDR/AJUBA/APOE/COL5A1/CHMP1A/SYT11/AP3B1/EPHB2/ARL8B/NOTCH2/PDGFRA/CD36/SERPINE2/IL6/STXBP1/TLR4/THBS1/MYOF/FGF2/ADAMTS18/SMAD4/FKBP10/CCN1/GNA12/AK3/ITGB1/DST/MERTK/DGKE/PRKCA/GNAQ/DMTN/ARHGAP35/ADAMTS13/ALOX15/WNT4/IL24/TGFBR2/PF4/PRKCD/ANXA5/F2RL2/CASP3/SHH/NOS3/SYK/FUNDC2/HPS6/PRDX2/PTK2/PRKCE/C1GALT1C1/FGG/FGA/JMJD1C/DAG1/SELP/HRAS/SMAD2/CHMP6/PLEC/F2/F2R/ANXA2/NOG/ADRA2C/PLSCR1/BLOC1S3/PPIA/MRTFA/SRC/MAP3K5/F5/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/SFTA3/TNF/TNF/HBB/ITGB3/ADAMTS13/PTEN 148
GO:0048511 rhythmic process 104/3662 270/15509 2.52028e-08 4.48871e-07 2.69943e-07 NFYA/CRY1/BMAL2/HSPA5/PER3/F7/NGFR/FBXW11/SIRT6/PGR/OPRK1/GSK3B/MMP2/DNM1L/ESR1/ADNP/PTN/CASP2/EZH2/AHR/MAPK8/RAI1/DDX5/HLF/MAP2K6/MDK/KAT2B/ID2/HDAC1/KDM5B/FOXO3/KLF9/ENOX1/EGR1/TARDBP/CRY2/INHBA/USP9X/ID1/NR1D1/FBXL12/ASS1/TOP2A/PER2/PRKAA1/MYBBP1A/BHLHE40/PDGFRA/NKX2-1/CYP1B1/CUL4A/IGF1R/ARRB2/CSNK1D/TNFRSF11A/DTL/PARP1/SLIT2/NONO/OGT/NTRK2/GAS2/ADAMTS1/KLF10/GNAQ/NR2F6/CASP3/CSF2/GDF9/ADCY1/NOS3/CDK5/ENOX2/BTRC/CDK1/KAT5/KDM2A/STAT5B/LEP/FZD4/A2M/CDK5R1/TYMS/OXTR/ADIPOQ/BTBD9/SLIT3/USP7/ZP3/SRC/ATG7/NTRK1/MTOR/CIPC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/PTEN 104
GO:0097696 receptor signaling pathway via STAT 70/3662 162/15509 2.58967e-08 4.59908e-07 2.76581e-07 IGF1/FGFR3/PTPRC/PIBF1/OSM/CD40/DOT1L/TGFB1/JAK3/HAMP/CCL2/HPX/SH2B3/IFNG/IL12B/IL4/IL5/PPP2CA/HES1/STAT1/GADD45A/PKD2/PTK2B/FLT3/STAT5A/LIF/EPO/EPHB2/ELP2/IL6/IL10/CYP1B1/IL21/EGF/NOTCH1/IL18/KIT/ADIPOR1/IL6R/JAK1/IL24/IL3/CSF2/CDK5/MST1/STAT5B/LEP/PTPN2/CDK5R1/F2/F2R/CSF1R/SOCS1/HGS/NF2/IFNA1/TNF/CRLF2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL10RB/GH1/PTPRC/CCL5/CCL5 70
GO:0032760 positive regulation of tumor necrosis factor production 49/3662 100/15509 2.65761e-08 4.70624e-07 2.83025e-07 BTK/TYROBP/CYBA/PTPRC/MAVS/PYCARD/NOD1/HSPB1/IFNG/IL17A/IL12B/WNT5A/IL1A/CLU/TNFRSF8/AKAP12/EPHB2/CD36/IL6/TLR4/THBS1/APP/PIK3R1/MAPKAPK2/PF4/TLR3/SYK/CYBB/NOD2/FADD/LGALS9/PTAFR/CD14/CCL19/LEP/LPL/PTPN11/CARD9/HMGB1/HLA-E/HLA-E/HLA-E/HLA-E/ORM1/HLA-E/HLA-E/HLA-E/PTPRC/MIF 49
GO:0007259 receptor signaling pathway via JAK-STAT 68/3662 156/15509 2.67517e-08 4.72267e-07 2.84013e-07 IGF1/FGFR3/PTPRC/PIBF1/OSM/CD40/DOT1L/JAK3/HAMP/CCL2/HPX/SH2B3/IFNG/IL12B/IL4/IL5/PPP2CA/HES1/STAT1/GADD45A/PKD2/PTK2B/FLT3/STAT5A/LIF/EPO/EPHB2/ELP2/IL6/IL10/CYP1B1/IL21/EGF/NOTCH1/IL18/KIT/ADIPOR1/IL6R/JAK1/IL24/IL3/CSF2/CDK5/MST1/STAT5B/LEP/PTPN2/CDK5R1/F2/F2R/CSF1R/SOCS1/HGS/NF2/IFNA1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL10RB/GH1/PTPRC/CCL5/CCL5 68
GO:0034504 protein localization to nucleus 103/3662 267/15509 2.68212e-08 4.72267e-07 2.84013e-07 TMEM98/PAF1/POLA2/CDH1/NGFR/TNPO3/IPO5/ELAVL1/SP100/HYAL2/SIRT6/GSK3B/XPO1/TNPO1/IPO11/MAVS/NUP50/HSP90AB1/RANGAP1/NFKBIA/BMP7/FERMT1/NXT2/KPNA3/TSC2/TGFB1/TNPO2/DNAJB6/DVL1/RANGRF/ZBTB16/ZPR1/IFNG/MAPK14/SKP1/KPNA1/PARK7/TARDBP/CRY2/CSE1L/CDKN1A/NUP153/NUP85/PIN1/LIF/SESN2/DKC1/SYNE1/NXT1/IPO8/CD36/MDFIC/AKIRIN2/CCT7/GLUL/XPA/TAF8/TRIM29/BBS4/TOR1AIP1/PARP1/PIK3R1/NOTCH1/BAG3/HHEX/RANBP2/HEATR3/APPL1/LMNA/PRKCD/TERT/SHH/CDK5/SYK/CCT2/CHP2/PKIG/NMD3/CDK1/TRIM8/ORMDL3/EIF2AK3/LEP/LARP7/CALR/F2/NPM1/CACNB4/PTTG1IP/SUMO3/NF2/LILRB4/RRP7A/IPO4/SRC/IPO9/IPO7/TXNIP/LILRB4/LILRB4/LILRB4/SQSTM1/IPO4 103
GO:0001935 endothelial cell proliferation 65/3662 147/15509 2.75667e-08 4.84019e-07 2.9108e-07 FLT4/CYBA/NGFR/TIE1/SIRT6/FGFR1/APOH/PDGFB/PPP1R16B/FLT1/PRKD2/TGFBR1/CXCL12/CCL2/MDK/IL12B/WNT5A/ITGA4/STAT1/PDCL3/NRP2/ARG1/PGF/TEK/NR4A1/BMP2/STAT5A/KDR/ALDH1A2/APOE/LOXL2/IL10/THBS1/FGF2/EGF/EPHA2/ARNT/VEGFC/BMP6/PRKCA/MMP14/EMC10/AIMP1/AGGF1/SCG2/CCL11/EGFL7/LEP/JUN/ERN1/HMGB1/NRARP/TNF/TNF/ZNF580/NRAS/TNF/TNF/TNF/TNF/TNF/TNF/PDCD6/ITGB3/AKT3 65
GO:0034341 response to interferon-gamma 62/3662 138/15509 2.76713e-08 4.84463e-07 2.91348e-07 SLC11A1/CD74/SP100/CDC42/IL12RB1/CD40/HCK/CCL22/CCL17/MEFV/RPS6KB1/CCL2/HPX/CYP27B1/IFNG/IL12B/WNT5A/CCL20/STAT1/FASLG/ARG1/ASS1/STXBP1/TLR4/CCL21/ACTR2/IRF8/GSN/CDC42EP2/GBP5/ADAMTS13/JAK1/TLR3/LGALS9/KIF5B/CCL11/CCL19/PDE12/PTPN2/CIITA/SOCS1/IFITM1/DAPK1/CD47/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HLA-DPA1/TNF/CCL5/CCL5/CCL4/CCL18/CCL4/CCL4/CCL18/CCL18/ADAMTS13 62
GO:0001822 kidney development 106/3662 277/15509 2.77484e-08 4.84463e-07 2.91348e-07 HOXA11/ITGA3/PROM1/IFT88/PRDM1/SEC61A1/FGFR2/RHOA/HYAL2/GLI2/NOTCH3/ITGA8/TP73/ARG2/LRP2/HSPB11/ZMPSTE24/BAX/ANGPT2/BAG6/PDGFB/MMP9/BMP7/SMAD7/RPGRIP1L/EYA1/SFRP1/TMEM59L/TGFBR1/GATA3/ACTA2/ZBTB16/SMAD5/PDGFRB/NPHP3/WNT5A/HES1/SNX17/STAT1/ODC1/SDC1/PKD2/HELLS/TEK/EGR1/CAT/SOX4/NUP85/BMP2/LIF/PODXL/ALDH1A2/FOXJ1/LAMA5/ASS1/RARA/NOTCH2/LRP4/PDGFRA/AHI1/EDNRB/TFAP2A/SMAD6/ARL3/PLCE1/FGF2/ENPEP/GREB1L/SMAD4/REN/SLIT2/ADAMTS16/KLHL3/NOTCH1/ARID5B/FREM2/BCL2L11/BMP6/ADAMTS1/IL6R/WNT4/VANGL2/PYGO2/HEYL/SHH/FADD/LAMB2/ZNG1A/SMAD2/CTNNBIP1/CXCR2/ADIPOQ/NOG/PBX1/MAGI2/WNT7B/MME/KANK2/BAG6/BAG6/BAG6/BAG6/BAG6/ITGB3/PECAM1/CD24 106
GO:0046640 regulation of alpha-beta T cell proliferation 33/3662 57/15509 2.87128e-08 4.99893e-07 3.00627e-07 FOXP3/ARG2/PTPRC/CD81/IL12B/ZAP70/TWSG1/NDFIP1/PTPN22/IL2RA/IL18/TGFBR2/SYK/LGALS9/CD28/CD55/HLA-E/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-A/HLA-E/PTPRC/ITCH 33
GO:0006914 autophagy 165/3662 478/15509 2.92408e-08 5.06241e-07 3.04444e-07 BAD/OSBPL7/DCN/UFL1/HGF/RRAGD/IFT88/ATP6V0A1/CLEC16A/PHF23/VMP1/CTSA/KDM4A/ROCK1/TBC1D25/SIRT2/VPS35/CSNK2A2/PRKACA/MARK2/MID2/GSK3B/ZMPSTE24/ATG16L1/CHMP5/DNM1L/NSFL1C/ABL1/SH3GLB1/SNAP29/XBP1/EEF1A2/CHMP4B/SRPX/NPRL3/TSC2/MEFV/PYCARD/SNRNP70/GSK3A/MET/NOD1/HSPB1/TRIM14/MAPK8/ACBD5/HSPA8/EIF4G2/IFNG/IL4/SNX4/ATP6V1A/TMEM59/PARK7/ELAPOR1/LEPR/MFN2/ATP6V0B/VAMP8/FOXO3/STBD1/CLU/CAPNS1/BECN1/ATG14/KDR/SESN2/CHMP1A/VPS25/C19orf12/TRIM5/TRIM22/PRKAA1/TBC1D14/SYT11/ARL8B/PTPN22/SNX14/VPS36/IL10/ATP6V1G1/GABARAPL1/TMBIM6/ULK3/IRF8/TRIM65/RETREG3/ABL2/SNAPIN/PLK2/KLHL3/TLK2/OGT/ATP6V1B2/C9orf72/SESN3/EI24/SOGA1/VPS51/FOXO1/ITPR1/VTI1A/BAG3/HSPB8/BCL2L11/UCHL1/ATP6V1C1/DRAM2/EEF1A1/TAB3/WIPI2/FYCO1/SLC25A46/CASP3/CDK5/TP53INP1/VCP/DEPP1/FUNDC2/ZFYVE1/GOLGA2/NOD2/TRIM68/UBXN6/ATG16L2/ADRB2/TRIM8/ORMDL3/SNX32/KAT5/GPR137/RNF213/ATP2A2/LEP/DDIT3/ATG13/CHMP6/TMEM39A/CDK5R1/WDR6/ERN1/YOD1/MAPK15/EXOC7/PRKN/HGS/CLN3/HMGB1/DAPK1/SRC/ATG7/SVIP/MTOR/DCAF12/RNF5/TRIM13/RIMOC1/FIS1/MAGEA3/PGAM5/IKBKG/LIX1L/PIP4K2B/SQSTM1/PRKACA 165
GO:0061919 process utilizing autophagic mechanism 165/3662 478/15509 2.92408e-08 5.06241e-07 3.04444e-07 BAD/OSBPL7/DCN/UFL1/HGF/RRAGD/IFT88/ATP6V0A1/CLEC16A/PHF23/VMP1/CTSA/KDM4A/ROCK1/TBC1D25/SIRT2/VPS35/CSNK2A2/PRKACA/MARK2/MID2/GSK3B/ZMPSTE24/ATG16L1/CHMP5/DNM1L/NSFL1C/ABL1/SH3GLB1/SNAP29/XBP1/EEF1A2/CHMP4B/SRPX/NPRL3/TSC2/MEFV/PYCARD/SNRNP70/GSK3A/MET/NOD1/HSPB1/TRIM14/MAPK8/ACBD5/HSPA8/EIF4G2/IFNG/IL4/SNX4/ATP6V1A/TMEM59/PARK7/ELAPOR1/LEPR/MFN2/ATP6V0B/VAMP8/FOXO3/STBD1/CLU/CAPNS1/BECN1/ATG14/KDR/SESN2/CHMP1A/VPS25/C19orf12/TRIM5/TRIM22/PRKAA1/TBC1D14/SYT11/ARL8B/PTPN22/SNX14/VPS36/IL10/ATP6V1G1/GABARAPL1/TMBIM6/ULK3/IRF8/TRIM65/RETREG3/ABL2/SNAPIN/PLK2/KLHL3/TLK2/OGT/ATP6V1B2/C9orf72/SESN3/EI24/SOGA1/VPS51/FOXO1/ITPR1/VTI1A/BAG3/HSPB8/BCL2L11/UCHL1/ATP6V1C1/DRAM2/EEF1A1/TAB3/WIPI2/FYCO1/SLC25A46/CASP3/CDK5/TP53INP1/VCP/DEPP1/FUNDC2/ZFYVE1/GOLGA2/NOD2/TRIM68/UBXN6/ATG16L2/ADRB2/TRIM8/ORMDL3/SNX32/KAT5/GPR137/RNF213/ATP2A2/LEP/DDIT3/ATG13/CHMP6/TMEM39A/CDK5R1/WDR6/ERN1/YOD1/MAPK15/EXOC7/PRKN/HGS/CLN3/HMGB1/DAPK1/SRC/ATG7/SVIP/MTOR/DCAF12/RNF5/TRIM13/RIMOC1/FIS1/MAGEA3/PGAM5/IKBKG/LIX1L/PIP4K2B/SQSTM1/PRKACA 165
GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell 22/3662 31/15509 3.15836e-08 5.45278e-07 3.27921e-07 SELE/RHOA/NFAT5/MDK/ITGA4/IL6/ITGB2/PTAFR/RELA/SELP/IRAK1/FUT4/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ELANE 22
GO:0046967 cytosol to endoplasmic reticulum transport 15/3662 17/15509 3.19596e-08 5.50238e-07 3.30903e-07 TAP1/ATP2A2/TAP2/TAP2/TAP1/TAP2/TAP2/TAP1/TAP2/TAP1/TAP1/TAP2/TAP1/TAP2/TAP2 15
GO:0071674 mononuclear cell migration 81/3662 197/15509 3.25393e-08 5.58667e-07 3.35973e-07 ITGAL/SPI1/RHOA/CDC42/TBX21/ICAM1/ABL1/PDGFB/CTSG/FLT1/CCL22/CCL17/PYCARD/IL27RA/PIK3CG/SERPINE1/CREB3/GATA3/CXCL12/C1QBP/CCL2/MDK/CALCA/NEDD9/IL4/WNT5A/CCL20/ZAP70/ITGA4/PADI2/PTK2B/CXCR4/CCR7/IL6/CCN3/CCL21/THBS1/TNFRSF11A/APP/ABL2/SLIT2/MSN/CXCL13/IL6R/CCR5/CXCR1/FADD/CX3CR1/LGALS9/PTK2/S1PR1/CCL11/CCL19/CYP7B1/PLEC/CALR/CXCR2/CSF1R/PLCB1/CSF1/HMGB1/FUT4/CD47/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/PECAM1/CCL5/CCL5/CCL4/CCL18/CCL4/CCL4/CCL18/CCL18 81
GO:0010594 regulation of endothelial cell migration 71/3662 166/15509 3.42218e-08 5.85931e-07 3.52369e-07 DCN/GRN/FLT4/ATP2B4/SP100/RHOA/FGFR1/APOH/ANGPT2/ABL1/PDGFB/CD40/GPI/PRKD2/TGFB1/PIK3CG/PTN/MET/HSPB1/GATA3/SMOC2/WNT5A/GADD45A/NRP2/TEK/PTK2B/RRAS/STAT5A/KDR/APOE/GLUL/THBS1/FGF2/EGF/EPHA2/RHOB/SLIT2/PLK2/NOTCH1/VEGFC/PRKCA/CXCL13/STC1/EMC10/NOS3/EFNA1/PTK2/SVBP/CALR/ADGRB1/CIB1/HMGB1/CSNK2B/TNF/TMSB4X/TNF/ZNF580/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PDCD6/ITGB3/AKT3/GPI 71
GO:0014015 positive regulation of gliogenesis 39/3662 73/15509 3.45974e-08 5.90729e-07 3.55254e-07 UFL1/TNFRSF1B/NTN1/TP73/LRP2/TGFB1/PTN/MDK/HES1/ID2/HDAC1/CXCR4/EGR2/IL1B/NKX2-2/BMP2/LIF/KRAS/SERPINE2/IL6/NOTCH1/VEGFC/SHH/DAG1/PLAG1/MTOR/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA 39
GO:0035966 response to topologically incorrect protein 69/3662 160/15509 3.57348e-08 6.06806e-07 3.64922e-07 MBTPS2/UFL1/BAK1/HSPA5/HERPUD1/EIF2AK2/ATXN3/DERL2/TMED2/PPP1R15A/BAX/BAG6/HSP90AB1/XBP1/UGGT2/BFAR/HSPB1/CREB3/TMEM33/HSPA8/CCND1/PACRG/HSPA9/HSPE1/MFN2/SERP1/CLU/TMTC4/HSPA2/CHAC1/AKIRIN2/ABCB10/DERL1/THBS1/TMBIM6/MANF/PIK3R1/DNAJB12/SERPINH1/BAG3/HSPB8/BCL2L11/PPP1R15B/ATF3/CREBRF/VCP/EIF2AK3/DDIT3/PTPN2/ERN1/YOD1/CREB3L2/PRKN/RNF5/HSPA1L/BAG6/DAXX/DAXX/HSPA1L/HSPA1L/DAXX/BAG6/DAXX/BAG6/DAXX/BAG6/HSPA1L/BAG6/HSPA1L 69
GO:0072331 signal transduction by p53 class mediator 69/3662 160/15509 3.57348e-08 6.06806e-07 3.64922e-07 KDM1A/E2F2/SNAI2/CD74/CD44/USP28/HIPK2/SP100/RPS6KA6/TP63/TP73/ZMPSTE24/ATRX/BAX/MAPKAPK5/MSH2/BAG6/PYCARD/NBN/YJU2/CASP2/ZNHIT1/DDX5/MAP2K6/FOXM1/NOP2/PERP/FOXO3/TRIM24/CDKN1A/SOX4/EEF1E1/DYRK2/SESN2/EDA2R/MYBBP1A/BRCA2/PMAIP1/DYRK3/TP53BP2/PLK2/POU4F2/POU4F1/ZNF385A/RPL26/SHISA5/DDIT4/HINT1/PPM1D/TRIAP1/KAT5/AURKB/NPM1/PTTG1IP/CHEK2/KMT5A/PRKN/MUC1/HEXIM1/USP7/SPRED2/MTOR/BAG6/BAG6/BAG6/BAG6/BAG6/BOP1/MIF 69
GO:0009896 positive regulation of catabolic process 160/3662 462/15509 3.70158e-08 6.26842e-07 3.76972e-07 BAD/UPF1/OSBPL7/MYLIP/DCN/PSMC4/RNF14/UFL1/IGF1/TNFRSF1B/HERPUD1/ATXN3/ROCK1/SIRT2/VPS35/NSF/MKRN2/MLH1/SIRT6/MID2/LRP2/GSK3B/TUT7/ATG16L1/BAX/PSMC5/P2RX7/HECTD1/BAG6/SH3GLB1/MARCHF2/PSMC6/SMAD7/AXIN1/NPRL3/TSC2/MEFV/SGTA/HAMP/GSK3A/NOD1/TRIM14/EXOSC3/DVL1/SH3D19/CD81/IFNG/USP5/IL4/WNT5A/SNX4/TMEM59/PARK7/ELAPOR1/CDC20/TNFAIP3/FBXL5/FOXO3/CLU/PTK2B/TARDBP/LRP1/CNOT1/IL1B/BECN1/ZFP36/KDR/CBFA2T3/APOE/SESN2/NDFIP1/TRIM5/TRIM22/PRKAA1/GRSF1/HSPBP1/APC/IL6/TTC5/SORL1/RDX/EGF/FURIN/TOB1/CSNK1D/TRIM65/APP/ARNT/DTL/POLR2D/CNOT9/PLK2/MSN/C9orf72/SESN3/FOXO1/RNF144A/BAG3/HSPB8/ZFP36L2/BCL2L11/CUL4B/CNOT11/ZC3H18/BTG2/PSMC2/DISC1/FABP1/RCHY1/FYCO1/PRKCD/TP53INP1/VCP/PSMC3/NOD2/TRIM68/GPD1/ADAM9/ADRB2/PTK2/PRKCE/TRIM8/ORMDL3/PAIP1/DCP2/KAT5/PDE12/ATG13/MAGEF1/RGMA/PRKN/ZFP36L1/YTHDF3/HMGB1/DAPK1/ATG7/SVIP/MTOR/GIGYF2/DXO/BAG6/TNF/TRIM13/TNF/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/GAS5/CEBPA/IKBKG/PIP4K2B/PTEN/ITCH 160
GO:0046633 alpha-beta T cell proliferation 34/3662 60/15509 3.7206e-08 6.27396e-07 3.77305e-07 FOXP3/ARG2/PTPRC/ELF4/CD81/IL12B/ZAP70/TWSG1/NDFIP1/PTPN22/IL2RA/IL18/TGFBR2/SYK/LGALS9/CD28/CD55/HLA-E/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-A/HLA-E/PTPRC/ITCH 34
GO:0010608 post-transcriptional regulation of gene expression 166/3662 483/15509 3.7251e-08 6.27396e-07 3.77305e-07 UPF1/SLC11A1/TNFRSF1B/EIF2AK2/PUM2/EIF4B/ELAVL1/PKM/RHOA/ROCK1/ELP1/MLH1/MKNK1/DDX1/BZW1/TUT7/ZMPSTE24/TMED2/PPP1R15A/MAPKAPK5/GCN1/FUS/AARS1/ALKBH5/ESR1/HNRNPC/AGO1/CIRBP/MKNK2/ZC3H7B/GZMB/ZC3H14/APEX1/PCIF1/TGFB1/DDX49/MTPN/HSPB1/EIF3B/EIF4H/EXOSC3/TRDMT1/LARP4B/CASC3/RPS6KB1/C1QBP/DDX5/DPH1/EIF4G2/DDX6/MAPK14/XRN1/EIF1B/NCL/PASK/DPH5/FOXO3/EIF2B2/NRDE2/MTRF1/PAIP2/SERP1/PTK2B/TARDBP/ZC3H7A/SOX4/CNOT1/TRAP1/ATG14/ZFP36/AJUBA/SESN2/DKC1/RARA/PER2/MYCN/ELP2/NIBAN1/EIF4E2/IL6/BZW2/IREB2/NCBP1/THBS1/CYP1B1/LARP1B/TARBP2/TOB1/EIF4A3/GRB7/APP/POLR2D/CNOT9/EGFR/EIF3H/EIF4EBP2/MTG1/CDC123/GUF1/ZFP36L2/CARHSP1/PRKCA/RMND1/USP16/EIF4A2/CNOT11/ZC3H18/PPP1R15B/BTG2/ZNF385A/RPL26/MAPKAPK2/PRKCD/TERT/FASTK/RPUSD4/TRUB1/PTAFR/ELP5/PA2G4/ENC1/EIF2AK3/PAIP1/CLP1/DCP2/EIF1/ANGEL2/PDE12/TYMS/SHMT1/CD28/CALR/TRNAU1AP/NPM1/RBM10/KLHL25/EIF3C/ZFP36L1/YTHDF3/SECISBP2/FOCAD/DAPK1/MTOR/SELENOT/SPOUT1/GIGYF2/DXO/TNF/SARNP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GAS5/EIF6/NEAT1/PRKDC/LSM14A/RBM8A/SPACA6-AS1/CCL5/CCL5/TAF15 166
GO:0034620 cellular response to unfolded protein 48/3662 98/15509 3.7372e-08 6.27728e-07 3.77505e-07 MBTPS2/UFL1/BAK1/HSPA5/HERPUD1/EIF2AK2/DERL2/TMED2/PPP1R15A/BAX/XBP1/BFAR/CREB3/TMEM33/HSPA8/CCND1/PACRG/HSPA9/SERP1/TMTC4/HSPA2/ABCB10/DERL1/TMBIM6/PIK3R1/BAG3/HSPB8/BCL2L11/PPP1R15B/ATF3/VCP/EIF2AK3/DDIT3/PTPN2/ERN1/YOD1/CREB3L2/PRKN/HSPA1L/DAXX/DAXX/HSPA1L/HSPA1L/DAXX/DAXX/DAXX/HSPA1L/HSPA1L 48
GO:0001655 urogenital system development 120/3662 325/15509 3.75105e-08 6.28351e-07 3.77879e-07 HOXA11/ITGA3/PROM1/IFT88/PRDM1/SEC61A1/FGFR2/RHOA/HYAL2/TP63/GLI2/NOTCH3/ITGA8/HOXA9/TP73/ARG2/LRP2/HSPB11/ZMPSTE24/BAX/MMP2/ESR1/ANGPT2/BAG6/PDGFB/MMP9/BMP7/SMAD7/RPGRIP1L/EYA1/SFRP1/TMEM59L/TGFBR1/GATA3/ACTA2/ZBTB16/SMAD5/PDGFRB/NPHP3/WNT5A/HES1/SNX17/STAT1/ODC1/SDC1/PKD2/HELLS/TEK/EGR1/CAT/SOX4/NUP85/BMP2/LIF/PODXL/ALDH1A2/FOXJ1/LAMA5/ASS1/RARA/EPHB2/NOTCH2/LRP4/PDGFRA/AHI1/EDNRB/TFAP2A/SMAD6/CYP19A1/ARL3/PLCE1/FGF2/ENPEP/GREB1L/SMAD4/REN/SLIT2/ADAMTS16/KLHL3/NOTCH1/ARID5B/FREM2/BCL2L11/BMP6/ADAMTS1/IL6R/WNT4/VANGL2/PYGO2/HEYL/SHH/TTC8/FRS2/FADD/LAMB2/ZNG1A/CYP7B1/RARG/SMAD2/CTNNBIP1/CXCR2/ADIPOQ/PLAG1/EPHB3/NOG/PBX1/MAGI2/WNT7B/MME/KANK2/BAG6/BAG6/BAG6/BAG6/BAG6/HOXA10/ITGB3/PECAM1/CD24/PTEN 120
GO:0002687 positive regulation of leukocyte migration 65/3662 148/15509 3.79187e-08 6.33478e-07 3.80963e-07 CD74/F7/SPI1/RHOA/DNM1L/ICAM1/ABL1/PYCARD/PTN/SERPINE1/CREB3/CXCL12/C1QBP/MDK/NEDD9/IL4/WNT5A/IL1A/CCL20/ITGA4/PGF/PTK2B/CCR7/RAC2/IL6/CCL21/THBS1/APP/ABL2/PIK3R1/VEGFC/CXCL13/MMP14/IL6R/FADD/CX3CR1/LGALS9/PTK2/PTAFR/CXCL8/CCL19/SELP/CALR/CXCR2/CSF1R/CSF1/ZP3/HMGB1/FUT4/CD47/TNF/TNF/ZNF580/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/CCL5/CCL5/CCL4/CCL4/CCL4 65
GO:2001236 regulation of extrinsic apoptotic signaling pathway 64/3662 145/15509 3.82375e-08 6.37085e-07 3.83132e-07 IGF1/SNAI2/HGF/TRAF1/SP100/HYAL2/FGFR1/PTPRC/GSK3B/ICAM1/SRPX/GATA1/PYCARD/EYA1/SFRP1/IL7/SERPINE1/TGFBR1/UNC5B/RPS6KB1/EYA4/IL4/IL1A/PARK7/TNFAIP3/TNFSF10/INHBA/IL1B/RBCK1/PSME3/ITM2C/THBS1/ITGAV/COL2A1/PMAIP1/TCF7L2/FAIM/LMNA/PEA15/ATF3/PF4/TERT/CSF2/GPER1/NOS3/PRDX2/FADD/BCL2L1/FGG/FGA/SCG2/RELA/PAK2/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC/PTEN 64
GO:1904994 regulation of leukocyte adhesion to vascular endothelial cell 25/3662 38/15509 3.92109e-08 6.51553e-07 3.91832e-07 SELE/RHOA/NFAT5/CXCL12/MDK/ITGA4/IL6/CCL21/ITGB2/PTAFR/RELA/SELP/ZDHHC21/IRAK1/FUT4/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ELANE 25
GO:0010632 regulation of epithelial cell migration 88/3662 220/15509 3.93805e-08 6.52249e-07 3.92251e-07 ITGA3/DCN/GRN/FLT4/ATP2B4/SP100/RHOA/FGFR1/APOH/ANGPT2/ABL1/PDGFB/MMP9/CD40/RAB11A/GPI/PRKD2/TGFB1/PIK3CG/PTN/MET/HSPB1/GATA3/CORO1C/IFNG/SMOC2/HBEGF/IL4/WNT5A/GADD45A/NRP2/TEK/PTK2B/RRAS/STAT5A/KDR/APOE/GLUL/THBS1/FGF2/EGF/EPHA2/DUSP10/RHOB/SLIT2/PLK2/NOTCH1/VEGFC/PRKCA/CXCL13/STC1/ADIPOR1/EMC10/TGFBR2/NOS3/MAPRE2/ADAM9/EFNA1/PTK2/PRKCE/JUN/SVBP/CALR/ADGRB1/CIB1/HMGB1/SRC/MTOR/CSNK2B/TNF/TMSB4X/TNF/ZNF580/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PDCD6/ITGB3/AKT3/GPI/PTEN 88
GO:0002639 positive regulation of immunoglobulin production 32/3662 55/15509 3.95022e-08 6.52249e-07 3.92251e-07 BTK/TBX21/MLH1/IL4R/PTPRC/MSH2/XBP1/CD40/GPI/TGFB1/EXOSC3/NSD2/HPX/IL4/IL5/CD86/SHLD2/EPHB2/IL6/IL10/IL21/TNFSF13/CD28/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/PTPRC/GPI 32
GO:0002347 response to tumor cell 30/3662 50/15509 3.95685e-08 6.52249e-07 3.92251e-07 DLEC1/SPI1/AHR/IL12B/CD160/TNFRSF10B/NECTIN2/NOTCH2/IGFBPL1/RBMS3/NOTCH1/MR1/PRDX2/RELA/PRF1/MICA/HMGB1/DAPK1/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/MICA/HLA-A/MICA/MICA/HLA-A/TXNIP 30
GO:1990874 vascular associated smooth muscle cell proliferation 37/3662 68/15509 4.07845e-08 6.7051e-07 4.03233e-07 IGF1/RHOA/MMP2/PDGFB/MMP9/BMPR1A/MFN2/NR4A3/GNA13/CDKN1A/DNMT1/IL10/FGF2/GNA12/GJA1/ADAMTS1/LDLRAP1/TERT/GPER1/NDRG2/FRS2/DDIT3/JUN/ERN1/ADIPOQ/RBM10/SRC/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTEN 37
GO:1903557 positive regulation of tumor necrosis factor superfamily cytokine production 50/3662 104/15509 4.21702e-08 6.91458e-07 4.15831e-07 BTK/TYROBP/CYBA/PTPRC/MAVS/PYCARD/NOD1/HSPB1/IFNG/IL17A/IL12B/CD86/WNT5A/IL1A/CLU/TNFRSF8/AKAP12/EPHB2/CD36/IL6/TLR4/THBS1/APP/PIK3R1/MAPKAPK2/PF4/TLR3/SYK/CYBB/NOD2/FADD/LGALS9/PTAFR/CD14/CCL19/LEP/LPL/PTPN11/CARD9/HMGB1/HLA-E/HLA-E/HLA-E/HLA-E/ORM1/HLA-E/HLA-E/HLA-E/PTPRC/MIF 50
GO:0002643 regulation of tolerance induction 24/3662 36/15509 5.00395e-08 8.1617e-07 4.9083e-07 FOXP3/CLC/FOXJ1/IL2RA/TGFBR2/LILRB4/HMGB1/HLA-G/HLA-B/HLA-G/HLA-B/HLA-B/HLA-B/HLA-G/HLA-B/HLA-G/HLA-G/HLA-G/HLA-G/LILRB4/HLA-G/LILRB4/LILRB4/ITCH 24
GO:0045671 negative regulation of osteoclast differentiation 24/3662 36/15509 5.00395e-08 8.1617e-07 4.9083e-07 LTF/SFRP1/LILRB1/IL4/IAPP/LRRC17/PIAS3/TLR4/TCTA/PIK3R1/TLR3/TNFRSF11B/INPP5D/GPR137/LILRB4/MAFB/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D 24
GO:0071346 cellular response to interferon-gamma 55/3662 119/15509 5.06108e-08 8.23322e-07 4.95131e-07 SP100/CDC42/IL12RB1/HCK/CCL22/CCL17/RPS6KB1/CCL2/HPX/IFNG/IL12B/WNT5A/CCL20/STAT1/FASLG/ARG1/ASS1/STXBP1/TLR4/CCL21/ACTR2/IRF8/GSN/CDC42EP2/GBP5/ADAMTS13/JAK1/TLR3/LGALS9/KIF5B/CCL11/CCL19/PDE12/PTPN2/SOCS1/DAPK1/CD47/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HLA-DPA1/TNF/CCL5/CCL5/CCL4/CCL18/CCL4/CCL4/CCL18/CCL18/ADAMTS13 55
GO:0014009 glial cell proliferation 33/3662 58/15509 5.15434e-08 8.36299e-07 5.02935e-07 UFL1/NTN1/AREG/HES1/LEPR/CLU/PTK2B/SOX4/IL1B/KRAS/IL6/RB1/NOTCH1/VEGFC/SKI/SHH/PLAG1/CSF1R/CSF1/NF2/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA 33
GO:0061756 leukocyte adhesion to vascular endothelial cell 31/3662 53/15509 5.42619e-08 8.75821e-07 5.26703e-07 SELE/RHOA/ROCK1/ADD2/NFAT5/CXCL12/MDK/ITGA4/IL6/CCL21/ITGB1/ITGB2/VCAM1/CX3CR1/PTAFR/RELA/SELP/LEP/ZDHHC21/IRAK1/FUT4/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ELANE 31
GO:1904894 positive regulation of receptor signaling pathway via STAT 31/3662 53/15509 5.42619e-08 8.75821e-07 5.26703e-07 PIBF1/TGFB1/IL12B/IL4/IL5/HES1/PTK2B/IL6/IL10/CYP1B1/NOTCH1/KIT/ADIPOR1/IL6R/LEP/F2/F2R/SOCS1/TNF/CRLF2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL10RB/GH1/CCL5/CCL5 31
GO:0048285 organelle fission 163/3662 475/15509 5.55682e-08 8.94575e-07 5.37982e-07 CDC27/BAZ1B/DCN/IGF1/SPAST/ARID1B/RAD51/MSH4/RHOA/SIRT2/VPS35/CDC42/SMC1A/NDE1/ACTB/MLH1/SPAG5/NDC80/PIBF1/ATRX/SEH1L/RAD54L/CHMP5/ZW10/DNM1L/TPX2/NSFL1C/ANAPC5/BIRC5/NUDC/KIF4A/CDC6/BAG6/BCL7C/SMARCB1/PDGFB/CCNB1IP1/MYBL2/BMP7/CDC25B/CHMP4B/UBE2I/RAB11A/ARHGEF10/CCNE1/BCCIP/SMC3/SMARCD2/CORO1C/BCL7A/FBXO5/CUL9/RAD50/MACROH2A1/PDGFRB/SMC4/KAT2B/WNT5A/IL1A/CDC20/NSL1/ARID1A/SLF2/MASTL/TEX14/NAA50/PDS5A/CENPK/OBSL1/KLHDC3/IL1B/BECN1/HSPA2/PIN1/PKMYT1/KDR/LIF/MAU2/CEP85/CHMP1A/TOP2A/BRME1/AP3B1/CCNA1/CCNB1/PSRC1/CDCA8/APC/BORA/NUMA1/NUSAP1/KIF23/ACTR2/CENPE/EGF/BRCA2/RB1/KIF2C/CENPC/BOD1/NCAPG2/MKI67/SPC25/BCL2L11/SMARCA5/SYCP2L/EME1/USP16/WNT4/PEX19/MAP9/SLC25A46/REEP3/RPL10L/BRD7/GOLGA2/MFF/BUB1/CENPX/PDE3A/KAT5/TDRD12/ZWILCH/CCNE2/BANF1/AURKAIP1/CHMP6/ANKLE2/MIEF2/CD28/RMI1/AURKB/CALR/MAPK15/PLCB1/CHEK2/KMT5A/PRKN/DRG1/ARID2/BAG6/TNF/SYCE1L/TNF/FIS1/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/KIFC1/PDXP/MTFP1/PGAM5/LSM14A/SMARCB1/NDE1/SPICE1 163
GO:0072593 reactive oxygen species metabolic process 86/3662 215/15509 5.5968e-08 8.98677e-07 5.40449e-07 MPO/NOX1/TYROBP/CYBA/RHOA/PDK3/SIRT2/ARG2/NOX4/P2RX7/PDGFB/BMP7/ACP5/TGFB1/SH3PXD2A/CRYAB/FOXM1/MAPK14/NNT/PDGFRB/PARK7/GADD45A/PRDX1/FOXO3/PTK2B/CAT/SIRT5/CDKN1A/BECN1/TRAP1/RAC2/PXDN/SESN2/SFTPD/CD36/TLR4/TFAP2A/THBS1/CYP1B1/CYP1A1/CYP1A2/PMAIP1/SOD1/CCN1/FOXO1/NDUFC2/FANCC/ITGB2/TGFBR2/PRKCD/STK17A/NOS3/SYK/CYBB/PRDX2/DDIT4/ITGAM/SLC25A33/LEP/GRIN1/GRB2/F2/NQO1/ADGRB1/PRKN/AKR1C3/SLC5A3/TNF/CD177/TNF/GPX3/NDUFS3/HBE1/HBD/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/HBB/HP/LOC102724560/AATF/TPO 86
GO:0031663 lipopolysaccharide-mediated signaling pathway 36/3662 66/15509 5.70278e-08 9.10975e-07 5.47844e-07 LTF/SPI1/NFKBIA/HCK/TGFB1/CCL2/MAPK14/TNFAIP3/IL1B/IRF3/TRIM5/PTPN22/CD36/TLR4/IL18/BMP6/PRKCA/NOS3/PRDX2/PTAFR/CD14/PRKCE/IRAK1/SIGIRR/CD55/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CCL5/CCL5/MIF 36
GO:0061614 miRNA transcription 36/3662 66/15509 5.70278e-08 9.10975e-07 5.47844e-07 NGFR/SPI1/PDGFB/TGFB1/GATA3/BMPR1A/DDX5/PPARD/MYB/FOXO3/EGR1/BMP2/RARA/IL10/SMAD6/FGF2/SMAD4/TERT/FOS/RELA/FOSL1/JUN/LILRB4/TEAD1/MRTFA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/LILRB4/LILRB4/LILRB4 36
GO:0009410 response to xenobiotic stimulus 139/3662 392/15509 5.87573e-08 9.35803e-07 5.62775e-07 BAD/CD38/ITGA3/CPS1/ABCC2/BAK1/CDH1/HSPA5/RAD51/CYBA/KCNQ1/KCNH2/CDH3/PDE4A/RHOA/TP73/XRCC5/OXCT1/ABCB1/RAD54L/MMP2/P2RX7/HSP90AB1/ABL1/CYP2D6/CBX7/APEX1/NFATC2/ABCC1/SFRP1/CYP3A5/AHR/ENG/GATA3/RPS6KB1/RECQL5/ABCC3/EFTUD2/MAP2K6/CCND1/MDK/SLCO1B3/STAT1/IGFBP2/ARG1/FOXO3/PGF/DNMT3A/PTK2B/CAT/CXCR4/INHBA/ABCC4/IL1B/FOSB/BECN1/CYP2E1/ASS1/PRKAA1/GSTM1/IL10/TPMT/THBS1/CYP1B1/RB1/CYP1A1/CYP1A2/SOD1/GUK1/EPHX1/REN/GNA12/ALAD/GSTO1/VEGFC/UCHL1/XPC/NAT2/CBR3/CYP3A4/RNF149/ATP1A1/TGFBR2/CASP3/TLR3/ADCY1/TNFRSF11B/CYBB/CYP2C19/MCM7/NNMT/SRP68/ABCA3/CDK1/FOS/MGMT/NAT1/PDE3A/CES3/LPL/FOSL1/GRIN1/TYMS/JUN/CALR/OXTR/NQO1/ADIPOQ/SLC8A1/CHEK2/PDE4B/KCNJ11/CARD9/BLOC1S3/SRC/CYP2B6/NTRK1/PNP/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/ITGB3/TXNIP/CYP2D6/CYP2D6/ABCC1/CYP2D6/CYP2D6/CYP2D6 139
GO:0071902 positive regulation of protein serine/threonine kinase activity 85/3662 212/15509 5.8884e-08 9.35803e-07 5.62775e-07 DBF4/LTF/ATP2B4/RHOA/FGFR1/PTPRC/NOX4/P2RX7/CCNK/CDC6/HSP90AB1/PDGFB/TCL1A/CD40/CD40LG/FLT1/AXIN1/CSK/TGFB1/PIK3CG/EZH2/BMPR1A/DKK1/MAP2K6/CCND1/FZD10/IFNG/CCND3/PPP2CA/PDGFRB/WNT5A/PKD2/PTK2B/FLT3/IL1B/BMP2/AJUBA/CCNB1/PSRC1/SPRY2/TLR4/THBS1/FGF2/EGF/MAP3K12/TNFRSF11A/CALM2/PDGFC/EGFR/HMGA2/KIT/CALM3/DVL3/DBF4B/RICTOR/SYK/NOD2/ADAM9/ADRB2/CCL19/CKS1B/HRAS/FZD4/CDK5R1/ERN1/ADIPOQ/CSF1R/IRAK1/CIB1/SRC/MAP3K5/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/PTPRC/CD24/MIF/ELANE 85
GO:0070482 response to oxygen levels 116/3662 314/15509 6.09635e-08 9.66373e-07 5.8116e-07 BAD/CD38/NOX1/FAS/CASR/CYBA/F7/HIPK2/RHOA/PDK3/SIRT2/ATP6AP1/MMP2/ALKBH5/ANGPT2/BMP7/SFRP1/PLAT/CXCL12/CRYAB/SLC11A2/PPARD/SLC29A1/PDGFRB/ATP6V1A/IL1A/EPAS1/SLC2A1/MPL/FOXO3/PGF/DNMT3A/EGR1/PTK2B/CAT/CXCR4/BMP2/BECN1/PIN1/HP1BP3/GNGT1/AJUBA/CBFA2T3/EPO/PRKAA1/LOXL2/ATP6V1G1/THBS1/TMBIM6/BNIP2/CYP1A1/SMAD4/PMAIP1/ARNT/PKLR/PSEN2/CCNA2/ALAD/NOTCH1/VEGFC/FOXO1/ITPR1/POU4F2/NR4A2/DDAH1/MMP14/ALAS2/NDUFS2/STC1/LMNA/AK4/VCAM1/CAPN2/ERCC3/TGFBR2/FABP1/CASP3/TERT/CYBB/AQP3/HIF1AN/DDIT4/RBPJ/FOS/PRKCE/ARNT2/LEP/OXTR/ADIPOQ/SLC8A1/IRAK1/ZFP36L1/P2RX2/SRC/ATG7/DPP4/MTOR/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/ADSL/TMEM199/PKLR/CD24/LOC102724560/PTEN 116
GO:0014013 regulation of gliogenesis 50/3662 105/15509 6.21629e-08 9.82871e-07 5.91081e-07 TMEM98/UFL1/TNFRSF1B/NTN1/KDM4A/SIRT2/TP73/LRP2/TGFB1/PTN/EZH2/MDK/HES1/ID2/HDAC1/CXCR4/EGR2/IL1B/NKX2-2/BMP2/NR1D1/LIF/KRAS/SERPINE2/IL6/RB1/DUSP10/NOTCH1/VEGFC/SKI/SHH/DAG1/F2/PLAG1/NOG/NF2/MTOR/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA 50
GO:0045581 negative regulation of T cell differentiation 26/3662 41/15509 6.44511e-08 1.01646e-06 6.1128e-07 CD74/RUNX3/FOXP3/CBFB/TBX21/IL4R/SMAD7/JAK3/MDK/IL4/BCL6/FOXJ1/HLX/RUNX1/CTLA4/SHH/PRDX2/RAG2/PTPN2/SOCS1/LILRB4/HMGB1/NRARP/LILRB4/LILRB4/LILRB4 26
GO:0002763 positive regulation of myeloid leukocyte differentiation 34/3662 61/15509 6.50316e-08 1.02301e-06 6.1522e-07 CD4/TYROBP/CD74/ACIN1/TGFB1/IFNG/NEDD9/IL17A/IL12B/IL5/ID2/LIF/NOTCH2/RB1/POU4F2/POU4F1/PRKCA/KLF10/RUNX1/PF4/SLC9B2/FADD/FOS/CTNNBIP1/CSF1/ZFP36L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 34
GO:0018209 peptidyl-serine modification 112/3662 301/15509 6.61392e-08 1.0378e-06 6.24114e-07 DYRK4/DCN/CLK1/HGF/CD44/BAK1/FNIP2/HPF1/ATP2B4/HIPK2/ROCK1/PDK3/CSNK2A2/PRKACA/RPS6KA6/MARK2/MKNK1/GSK3B/MAST2/BAX/MAPKAPK5/HSP90AB1/CDC7/MKNK2/OSM/PDGFB/TCL1A/RASSF2/SMAD7/AXIN1/PRKD2/TGFB1/GSK3A/TGFBR1/MAPK8/DKK1/CSF3/RPS6KB1/IFNG/MAPK14/PDE4D/WNT5A/GALNT3/PARK7/GADD45A/MASTL/PKN1/DYRK2/LIF/EPO/PRKAA1/NGF/SRPK2/SPRY2/IL6/MAP3K12/ULK3/ARRB2/CSNK1D/APP/DYRK3/CNOT9/PLK2/EGFR/TLK2/NTRK2/CNKSR3/PRKCA/DMTN/PKN3/SPTBN4/BRSK1/MAPKAPK2/IL24/POGLUT1/TGFBR2/PRKCD/EGFLAM/RICTOR/CDK5/SYK/NSD1/STK32C/DDIT4/CDK1/PRKCE/EIF2AK3/BRSK2/BDNF/CDK5R1/ERN1/PAK2/CHEK2/INPP5J/SPOCK3/SRC/IFNA1/MTOR/TNF/TNF/CHUK/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/AKT3/MIF/PTEN/PRKACA 112
GO:0032945 negative regulation of mononuclear cell proliferation 46/3662 94/15509 7.39226e-08 1.15409e-06 6.94047e-07 BTK/TYROBP/FOXP3/FCGR2B/ARG2/LILRB1/CD86/ARG1/CD80/PKN1/TWSG1/FOXJ1/NDFIP1/SFTPD/IL2RA/IL10/TNFRSF21/CTLA4/CASP3/SHH/INPP5D/LGALS9/CEBPB/GLMN/LILRB4/PDCD1LG2/CR1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/TNFRSF13B/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 46
GO:0050672 negative regulation of lymphocyte proliferation 46/3662 94/15509 7.39226e-08 1.15409e-06 6.94047e-07 BTK/TYROBP/FOXP3/FCGR2B/ARG2/LILRB1/CD86/ARG1/CD80/PKN1/TWSG1/FOXJ1/NDFIP1/SFTPD/IL2RA/IL10/TNFRSF21/CTLA4/CASP3/SHH/INPP5D/LGALS9/CEBPB/GLMN/LILRB4/PDCD1LG2/CR1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/TNFRSF13B/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 46
GO:0060558 regulation of calcidiol 1-monooxygenase activity 13/3662 14/15509 7.63205e-08 1.18853e-06 7.1476e-07 CYP27B1/VDR/IFNG/IL1B/GFI1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 13
GO:0006417 regulation of translation 126/3662 349/15509 7.67305e-08 1.19192e-06 7.16799e-07 UPF1/EIF2AK2/PUM2/EIF4B/ELAVL1/PKM/RHOA/ROCK1/ELP1/MLH1/MKNK1/DDX1/BZW1/TUT7/TMED2/PPP1R15A/MAPKAPK5/GCN1/AARS1/AGO1/CIRBP/MKNK2/GZMB/PCIF1/MTPN/HSPB1/EIF3B/EIF4H/EXOSC3/LARP4B/CASC3/RPS6KB1/C1QBP/DPH1/EIF4G2/DDX6/XRN1/EIF1B/NCL/PASK/DPH5/FOXO3/EIF2B2/MTRF1/PAIP2/SERP1/PTK2B/TARDBP/SOX4/CNOT1/TRAP1/ZFP36/SESN2/RARA/PER2/ELP2/NIBAN1/EIF4E2/IL6/BZW2/IREB2/NCBP1/THBS1/CYP1B1/LARP1B/TARBP2/TOB1/EIF4A3/GRB7/APP/POLR2D/CNOT9/EIF3H/EIF4EBP2/MTG1/CDC123/GUF1/ZFP36L2/RMND1/USP16/EIF4A2/CNOT11/PPP1R15B/BTG2/ZNF385A/RPL26/RPUSD4/PTAFR/ELP5/PA2G4/ENC1/EIF2AK3/PAIP1/DCP2/EIF1/PDE12/TYMS/SHMT1/CD28/CALR/TRNAU1AP/NPM1/KLHL25/EIF3C/ZFP36L1/YTHDF3/SECISBP2/DAPK1/MTOR/SELENOT/GIGYF2/TNF/SARNP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/PRKDC/LSM14A/RBM8A/CCL5/CCL5 126
GO:0002923 regulation of humoral immune response mediated by circulating immunoglobulin 22/3662 32/15509 7.84563e-08 1.21568e-06 7.31089e-07 FCGR2B/PTPRC/FCER2/HPX/FOXJ1/NOD2/CD55/CR1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/PTPRC 22
GO:0032755 positive regulation of interleukin-6 production 47/3662 97/15509 7.8753e-08 1.21703e-06 7.31901e-07 BTK/TYROBP/CD74/POU2F2/CYBA/HYAL2/MAVS/P2RX7/XBP1/TLR8/PYCARD/NOD1/POU2AF1/IFNG/IL17A/WNT5A/IL1A/IL1B/CD36/AKIRIN2/IL6/TLR4/APP/IL6R/TLR3/SYK/NOD2/LGALS9/PTAFR/IL16/LEP/LPL/PTPN11/F2R/CARD9/HMGB1/IL1RAP/TLR7/MBP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 47
GO:0007254 JNK cascade 72/3662 172/15509 7.89361e-08 1.21703e-06 7.31901e-07 WNT16/PAFAH1B1/NOX1/MAPK8IP2/CASR/FLT4/TRAF1/HIPK2/MAP2K4/FCGR2B/TRAF4/MECOM/GADD45B/BIRC7/RASSF2/AXIN1/PYCARD/SFRP1/NOD1/FKTN/AMBP/MAPK8/WNT5A/IL1A/GADD45A/PTK2B/IL1B/CCR7/PRMT1/EDA2R/TRAF3/MEN1/PTPN22/MDFIC/TLR4/CCL21/MAP3K12/IGF1R/APP/DUSP10/EGFR/MBIP/TLR3/NOD2/GPS1/CCL19/HRAS/PLCB1/IRAK1/PRKN/CARD9/WNT7B/HMGB1/TLR7/MAP3K5/TNF/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF/NAIP/NAIP/NAIP/ITCH 72
GO:0018105 peptidyl-serine phosphorylation 106/3662 282/15509 8.14207e-08 1.25101e-06 7.52336e-07 DYRK4/CLK1/HGF/CD44/BAK1/FNIP2/ATP2B4/HIPK2/ROCK1/PDK3/CSNK2A2/PRKACA/RPS6KA6/MARK2/MKNK1/GSK3B/MAST2/BAX/MAPKAPK5/HSP90AB1/CDC7/MKNK2/OSM/PDGFB/TCL1A/RASSF2/SMAD7/AXIN1/PRKD2/TGFB1/GSK3A/TGFBR1/MAPK8/DKK1/CSF3/RPS6KB1/IFNG/MAPK14/PDE4D/WNT5A/PARK7/GADD45A/MASTL/PKN1/DYRK2/LIF/EPO/PRKAA1/NGF/SRPK2/SPRY2/IL6/MAP3K12/ULK3/ARRB2/CSNK1D/APP/DYRK3/CNOT9/PLK2/EGFR/TLK2/NTRK2/CNKSR3/PRKCA/DMTN/PKN3/SPTBN4/BRSK1/MAPKAPK2/IL24/TGFBR2/PRKCD/RICTOR/CDK5/SYK/NSD1/STK32C/DDIT4/CDK1/PRKCE/EIF2AK3/BRSK2/BDNF/CDK5R1/ERN1/PAK2/CHEK2/INPP5J/SRC/IFNA1/MTOR/TNF/TNF/CHUK/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/AKT3/MIF/PTEN/PRKACA 106
GO:1904951 positive regulation of establishment of protein localization 109/3662 292/15509 8.15438e-08 1.25101e-06 7.52336e-07 BAD/CD38/IGF1/CASR/CDH1/NNAT/IPO5/HYAL2/VPS35/CSNK2A2/PRKACA/SIRT6/PCM1/GSK3B/OXCT1/ACHE/DNM1L/MAVS/P2RX7/HSP90AB1/SH3GLB1/GZMB/PCK2/PARD6A/KCNN4/PDCD5/TGFB1/CD33/GSK3A/MAPK8/PPP3CB/ZPR1/CD81/PSMD9/IFNG/PPARD/MAPK14/TMEM30A/APBB3/IL1A/SERP1/TARDBP/ACSL3/SOX4/IL1B/ERGIC3/RAC2/DKC1/PRKAA1/XPO4/CCT7/GLUL/NMT1/TLR4/ANP32B/SORL1/CEP131/SAE1/PIK3R1/GLUD1/TCF7L2/VEGFC/BAG3/BMP6/ITGB2/PCNT/BAP1/PRKCD/SHH/GPER1/CDK5/CCT2/CHP2/ADAM9/MFF/ITGAM/CDK1/PRKCE/FGG/FGA/LEP/HRAS/CEP135/PDZK1/ATG13/CDK5R1/MIEF2/PTP4A3/CIB1/UBE2L3/CLN3/PPIA/SRC/UBL5/HSPA1L/TNF/HSPA1L/TNF/FIS1/TNF/HSPA1L/TNF/TNF/TNF/TNF/TNF/HSPA1L/HSPA1L/PRKACA 109
GO:0033673 negative regulation of kinase activity 82/3662 204/15509 8.79689e-08 1.34625e-06 8.09611e-07 MVP/IPO5/HYAL2/PTPRC/RTRAF/ABL1/GADD45B/PIK3IP1/GSKIP/BMP7/TSC2/PYCARD/CSK/SFRP1/HSPB1/DVL1/CHORDC1/CORO1C/SH2B3/IFNG/MACROH2A1/KAT2B/PRKAR2A/PARK7/GADD45A/TNFAIP3/PKN1/CDKN1A/IL1B/BMP2/AJUBA/CDKN1C/APOE/CEP85/VPS25/EPHB2/MEN1/PTPN22/APC/SPRY2/SORL1/TARBP2/RB1/WARS1/DUSP10/NCAPG2/HHEX/UCHL1/GNAQ/CAMK2N1/PRKCD/DUSP7/CASP3/PKIG/RGS14/PTPN2/CHMP6/PLEC/TAF7/PAK2/ADIPOQ/NPM1/SLC8A1/PRKN/NF2/LILRB4/HEXIM1/SPRY4/PPIA/AKT1S1/IPO7/DBNDD2/CEBPA/PTPRC/CDKN1C/LILRB4/PIP4K2B/LILRB4/LILRB4/LRP6/PTEN/CHORDC1 82
GO:0070302 regulation of stress-activated protein kinase signaling cascade 76/3662 185/15509 8.92565e-08 1.36259e-06 8.19438e-07 WNT16/PAFAH1B1/NOX1/MAPK8IP2/HGF/FAS/FLT4/EIF2AK2/TRAF1/HIPK2/MAP2K4/SPI1/FCGR2B/TRAF4/OPRK1/RNF13/ZMPSTE24/MECOM/GADD45B/BIRC7/RASSF2/AXIN1/PYCARD/SFRP1/NOD1/FKTN/AMBP/FOXM1/WNT5A/IL1A/GADD45A/PRDX1/PTK2B/IL1B/BMP2/CCR7/PRMT1/EDA2R/TRAF3/MEN1/PTPN22/MDFIC/TLR4/CCL21/IGF1R/APP/DUSP10/ARL6IP5/EGFR/FOXO1/MBIP/TLR3/NOD2/SEMA4C/CCL19/LEP/HRAS/PLCB1/PRKN/CARD9/WNT7B/HMGB1/PPIA/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NAIP/ITCH 76
GO:0006446 regulation of translational initiation 39/3662 75/15509 9.10726e-08 1.3869e-06 8.34056e-07 EIF2AK2/EIF4B/DDX1/BZW1/TMED2/PPP1R15A/HSPB1/EIF3B/EIF4H/RPS6KB1/EIF4G2/EIF1B/EIF2B2/PAIP2/BZW2/NCBP1/POLR2D/EIF3H/EIF4EBP2/CDC123/EIF4A2/PPP1R15B/EIF2AK3/PAIP1/EIF1/NPM1/KLHL25/YTHDF3/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CCL5/CCL5 39
GO:0043393 regulation of protein binding 75/3662 182/15509 9.29782e-08 1.41245e-06 8.49422e-07 KDM1A/HFE/HIPK2/BTBD1/ROCK1/CDC42/PRKACA/MARK2/ADD2/ACTB/GSK3B/BAX/ADD1/FKBP1A/HSP90AB1/ABL1/TFIP11/PDGFB/MMP9/ADNP/TLE5/TGFBR1/DVL1/MAPK8/DKK1/CSF3/PPP2CA/NPHP3/WNT5A/ITGA4/PARK7/IFIT2/TEX14/LRP1/USP9X/CDKN1A/BMP2/ID1/PIN1/APOE/PRMT7/MEN1/IL10/DERL1/SORL1/TDG/TMBIM6/ARRB2/APP/SNAPIN/TCF7L2/SPPL3/LDLRAP1/EPB41/DISC1/SPTA1/PRKCD/TERT/CDK5/GOLGA2/NMD3/ADRB2/ATP2A2/BDNF/CTNNBIP1/AURKB/ADIPOQ/PHLDA2/RGMA/ANXA2/NOG/PRKN/SRC/B2M/PRKACA 75
GO:0072001 renal system development 107/3662 286/15509 9.36541e-08 1.41924e-06 8.53504e-07 HOXA11/ITGA3/PROM1/IFT88/PRDM1/SEC61A1/FGFR2/RHOA/HYAL2/GLI2/NOTCH3/ITGA8/TP73/ARG2/LRP2/HSPB11/ZMPSTE24/BAX/ANGPT2/BAG6/PDGFB/MMP9/BMP7/SMAD7/RPGRIP1L/EYA1/SFRP1/TMEM59L/TGFBR1/GATA3/ACTA2/ZBTB16/SMAD5/PDGFRB/NPHP3/WNT5A/HES1/SNX17/STAT1/ODC1/SDC1/PKD2/HELLS/TEK/EGR1/CAT/SOX4/NUP85/BMP2/LIF/PODXL/ALDH1A2/FOXJ1/LAMA5/ASS1/RARA/NOTCH2/LRP4/PDGFRA/AHI1/EDNRB/TFAP2A/SMAD6/ARL3/PLCE1/FGF2/ENPEP/GREB1L/SMAD4/REN/SLIT2/ADAMTS16/KLHL3/NOTCH1/ARID5B/FREM2/BCL2L11/BMP6/ADAMTS1/IL6R/WNT4/VANGL2/PYGO2/HEYL/SHH/TTC8/FADD/LAMB2/ZNG1A/SMAD2/CTNNBIP1/CXCR2/ADIPOQ/NOG/PBX1/MAGI2/WNT7B/MME/KANK2/BAG6/BAG6/BAG6/BAG6/BAG6/ITGB3/PECAM1/CD24 107
GO:0030330 DNA damage response, signal transduction by p53 class mediator 36/3662 67/15509 9.53288e-08 1.43759e-06 8.64539e-07 KDM1A/SNAI2/CD74/CD44/HIPK2/SP100/RPS6KA6/ZMPSTE24/ATRX/NBN/YJU2/CASP2/ZNHIT1/DDX5/FOXM1/FOXO3/CDKN1A/SOX4/EEF1E1/SESN2/BRCA2/PMAIP1/DYRK3/PLK2/ZNF385A/RPL26/PPM1D/TRIAP1/KAT5/NPM1/PTTG1IP/CHEK2/KMT5A/MUC1/SPRED2/MIF 36
GO:1904705 regulation of vascular associated smooth muscle cell proliferation 36/3662 67/15509 9.53288e-08 1.43759e-06 8.64539e-07 IGF1/RHOA/MMP2/PDGFB/MMP9/BMPR1A/MFN2/NR4A3/GNA13/CDKN1A/DNMT1/IL10/FGF2/GNA12/GJA1/ADAMTS1/LDLRAP1/TERT/GPER1/NDRG2/FRS2/JUN/ERN1/ADIPOQ/RBM10/SRC/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTEN 36
GO:0062197 cellular response to chemical stress 115/3662 313/15509 9.73511e-08 1.46452e-06 8.80737e-07 BAD/WNT16/MPO/NOX1/BTK/HGF/GLRX2/FAS/AIFM2/TMEM161A/MYLK/SIRT2/XRCC5/SLC25A24/MMP2/PXN/ABL1/GSKIP/APEX1/DHRS2/MMP9/BMP7/NFAT5/ABCC1/PYCARD/GSR/MET/HSPB1/EZH2/MAPK8/PPIF/EPAS1/PARK7/SLC2A1/PRDX1/TNFAIP3/ARG1/FOXO3/PKD2/NR4A3/CAT/CHD6/STAU1/SLC25A23/BECN1/TRAP1/MGAT3/EPO/SESN2/PRKAA1/PDGFRA/CD36/IL6/IL10/TLR4/IL18BP/CYP1B1/MEAK7/SOD1/ARNT/PARP1/RHOB/ARL6IP5/EGFR/NONO/FOXO1/NR4A2/FANCC/AQP5/TBC1D24/SELENON/FABP1/PRKCD/CASP3/NOS3/TP53INP1/FXN/PRDX2/LETM1/CDK1/FOS/MGMT/EIF2AK3/RELA/ATP2A2/DDIT3/JUN/PLEC/ERN1/NQO1/PRKN/ZFP36L1/CLN3/AKR1C3/PPIA/DAPK1/SRC/MAP3K5/ATG7/MTOR/ZNF277/TNF/TNF/ZNF580/CHUK/TNF/TNF/TNF/TNF/TNF/TNF/GAS5/SRXN1/PCGF2/ABCC1 115
GO:0002920 regulation of humoral immune response 31/3662 54/15509 9.86272e-08 1.48012e-06 8.90121e-07 FCGR2B/PTPRC/CD59/FCER2/C1QBP/HPX/IL17A/IL1B/C3/CCR7/FOXJ1/CXCL13/NOD2/A2M/ZP3/CD55/CR1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/PTPRC 31
GO:0022612 gland morphogenesis 54/3662 118/15509 1.00727e-07 1.50798e-06 9.06872e-07 SNAI2/HGF/NTN1/FGFR2/TP63/PGR/BAX/MMP2/ESR1/XBP1/BMP7/LAMA1/SFRP1/TGFB1/PTN/AREG/MDK/VDR/WNT5A/KDM5B/TNFAIP3/ARG1/TWSG1/LAMA5/NOTCH2/IL6/EPHA2/EGFR/MSN/NOTCH1/WNT4/TGFBR2/SHH/BTRC/FRS2/CCL11/CEBPB/CYP7B1/RARG/DAG1/PLAG1/CSF1R/NOG/CSF1/SRC/TGM2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 54
GO:0006953 acute-phase response 29/3662 49/15509 1.0183e-07 1.51731e-06 9.12486e-07 HAMP/TFR2/IL1A/FN1/IL1B/EPO/ASS1/EDNRB/IL6/TNFRSF11A/IL6R/MBL2/CEBPB/A2M/CD163/F2/SIGIRR/PLSCR1/TRPV1/TNF/TNF/TNF/TNF/TNF/TNF/ORM1/TNF/TNF/HP 29
GO:0046328 regulation of JNK cascade 61/3662 139/15509 1.0184e-07 1.51731e-06 9.12486e-07 WNT16/PAFAH1B1/NOX1/MAPK8IP2/FLT4/TRAF1/HIPK2/MAP2K4/FCGR2B/TRAF4/MECOM/GADD45B/BIRC7/RASSF2/AXIN1/PYCARD/SFRP1/NOD1/FKTN/AMBP/WNT5A/IL1A/GADD45A/PTK2B/IL1B/CCR7/PRMT1/EDA2R/TRAF3/MEN1/PTPN22/MDFIC/TLR4/CCL21/IGF1R/APP/DUSP10/EGFR/MBIP/TLR3/NOD2/CCL19/HRAS/PLCB1/PRKN/CARD9/WNT7B/HMGB1/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NAIP/ITCH 61
GO:0071677 positive regulation of mononuclear cell migration 40/3662 78/15509 1.02757e-07 1.52732e-06 9.18501e-07 SPI1/RHOA/ABL1/PYCARD/SERPINE1/CREB3/CXCL12/C1QBP/NEDD9/IL4/WNT5A/CCL20/ITGA4/PTK2B/CCR7/CCL21/APP/ABL2/CXCL13/FADD/CX3CR1/LGALS9/CALR/CSF1/HMGB1/CD47/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/CCL5/CCL5/CCL4/CCL4/CCL4 40
GO:0000280 nuclear division 149/3662 430/15509 1.04563e-07 1.55044e-06 9.32408e-07 CDC27/BAZ1B/IGF1/SPAST/ARID1B/RAD51/MSH4/RHOA/SIRT2/CDC42/SMC1A/NDE1/ACTB/MLH1/SPAG5/NDC80/PIBF1/ATRX/SEH1L/RAD54L/CHMP5/ZW10/TPX2/NSFL1C/ANAPC5/BIRC5/NUDC/KIF4A/CDC6/BAG6/BCL7C/SMARCB1/PDGFB/CCNB1IP1/MYBL2/BMP7/CDC25B/CHMP4B/UBE2I/RAB11A/ARHGEF10/CCNE1/BCCIP/SMC3/SMARCD2/BCL7A/FBXO5/CUL9/RAD50/MACROH2A1/PDGFRB/SMC4/KAT2B/WNT5A/IL1A/CDC20/NSL1/ARID1A/SLF2/MASTL/TEX14/NAA50/PDS5A/CENPK/OBSL1/KLHDC3/IL1B/BECN1/HSPA2/PIN1/PKMYT1/LIF/MAU2/CEP85/CHMP1A/TOP2A/BRME1/CCNA1/CCNB1/PSRC1/CDCA8/APC/BORA/NUMA1/NUSAP1/KIF23/ACTR2/CENPE/EGF/BRCA2/RB1/KIF2C/CENPC/BOD1/NCAPG2/MKI67/SPC25/BCL2L11/SMARCA5/SYCP2L/EME1/USP16/WNT4/MAP9/REEP3/RPL10L/BRD7/GOLGA2/BUB1/CENPX/PDE3A/KAT5/TDRD12/ZWILCH/CCNE2/BANF1/AURKAIP1/CHMP6/ANKLE2/CD28/RMI1/AURKB/CALR/MAPK15/PLCB1/CHEK2/KMT5A/DRG1/ARID2/BAG6/TNF/SYCE1L/TNF/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/KIFC1/PDXP/LSM14A/SMARCB1/NDE1/SPICE1 149
GO:0030595 leukocyte chemotaxis 87/3662 221/15509 1.10237e-07 1.63067e-06 9.80657e-07 CD74/F7/SPI1/MMP2/DNM1L/PDGFB/CTSG/FLT1/CCL22/CCL17/PIK3CG/PTN/SERPINE1/CREB3/CXCL12/C1QBP/CCL2/MDK/CALCA/NEDD9/IL4/WNT5A/CCL20/PADI2/CSF3R/PGF/PTK2B/CXCR4/NUP85/IL1B/CCR7/SBDS/RAC2/MTUS1/SFTPD/EDNRB/IL6/IL10/CCN3/CCL21/THBS1/CYP19A1/TNFRSF11A/LYST/SLIT2/VEGFC/CXCL13/KIT/ITGB2/CXCR5/IL6R/CCR5/CXCR1/PF4/SYK/NOD2/CX3CR1/LGALS9/PTK2/CXCL8/S1PR1/SCG2/CCL11/BSG/IL16/CCL19/CYP7B1/PLEC/CALR/CXCR2/CSF1R/CSF1/PDE4B/CNR2/HMGB1/PPIA/DPP4/ZNF580/CCL5/CCL5/CCL4/CCL18/CCL4/MIF/CCL4/CCL18/CCL18 87
GO:0007260 tyrosine phosphorylation of STAT protein 41/3662 81/15509 1.14284e-07 1.68651e-06 1.01424e-06 IGF1/FGFR3/PIBF1/OSM/CD40/JAK3/HPX/SH2B3/IFNG/IL12B/IL4/PPP2CA/HES1/FLT3/LIF/EPO/IL6/IL21/IL18/KIT/IL6R/JAK1/IL24/IL3/CSF2/LEP/PTPN2/CSF1R/SOCS1/NF2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/CCL5/CCL5 41
GO:0002439 chronic inflammatory response to antigenic stimulus 14/3662 16/15509 1.20071e-07 1.75934e-06 1.05804e-06 IL10/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA 14
GO:0002874 regulation of chronic inflammatory response to antigenic stimulus 14/3662 16/15509 1.20071e-07 1.75934e-06 1.05804e-06 IL10/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA 14
GO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production 14/3662 16/15509 1.20071e-07 1.75934e-06 1.05804e-06 CD74/TLR4/LPL/HMGB1/MBP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MIF 14
GO:0034976 response to endoplasmic reticulum stress 93/3662 241/15509 1.2298e-07 1.79772e-06 1.08112e-06 MBTPS2/UFL1/BAK1/HSPA5/HERPUD1/EIF2AK2/RASGRF1/ATXN3/SEL1L/FCGR2B/DERL2/GSK3B/TMED2/PPP1R15A/BAX/BAG6/ABL1/XBP1/PSMC6/USP14/SRPX/UGGT2/BFAR/SGTA/CREB3/CCDC47/TMEM33/CCND1/UBE4A/MAN1A1/PARK7/SERP1/CLU/TNFRSF10B/TRIM25/TMTC4/CHAC1/SESN2/SERINC3/FBXO44/NIBAN1/ECPAS/DERL1/FAM8A1/RNF121/THBS1/TMBIM6/TMX1/PMAIP1/TMCO1/MANF/PIK3R1/ERLIN2/DNAJB12/ITPR1/BCL2L11/CLGN/USP25/PDIA4/PPP1R15B/ALOX15/ATF3/TMUB1/VCP/UBXN6/CXCL8/BCL2L1/EIF2AK3/CEBPB/ATP2A2/BRSK2/DDIT3/PTPN2/JUN/ERN1/GRINA/CALR/YOD1/CREB3L2/PRKN/MAP3K5/SVIP/UBE2J1/RNF5/BAG6/TRIM13/MAGEA3/BAG6/BAG6/BAG6/BAG6/FBXO17/MARCKS 93
GO:0001649 osteoblast differentiation 84/3662 212/15509 1.30111e-07 1.89748e-06 1.14111e-06 MRC2/LTF/UFL1/IGF1/SNAI2/HGF/FGFR2/CBFB/PRKACA/TP63/GLI2/GSK3B/ACHE/HNRNPC/BMP7/RASSF2/SFRP1/FBL/BMPR1A/WNT3/CCDC47/DDX5/MAP2K6/AREG/FBXO5/MAPK14/SMAD5/HSPE1/FHL2/SPP1/CAT/RUNX2/RRBP1/BMP2/TWSG1/MYBBP1A/HSD17B4/MEN1/IL6/ITGA11/SMAD6/FGF2/FBN2/TOB1/SMAD4/EPHA2/CCN1/IGFBP3/RBMX/NOTCH1/VEGFC/CRIM1/BMP6/SKI/IL6R/PSMC2/WNT4/H3-3A/RANBP3L/SHH/TPM4/PTK2/RIOX1/CEBPB/ESRRA/FAM20C/CTNNBIP1/NOG/IFITM1/WNT7B/TNF/TNF/CEBPD/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/CRIM1/WNT3/WNT3/PRKACA 84
GO:0050729 positive regulation of inflammatory response 64/3662 149/15509 1.31938e-07 1.91961e-06 1.15442e-06 BTK/GRN/KARS1/HYAL2/OSM/NFKBIA/ABCC1/PYCARD/PIK3CG/SERPINE1/CTSC/MDK/CD81/IFNG/IL12B/WNT5A/SNX4/PARK7/VAMP8/IL1B/C3/CCR7/IL6/TLR4/IL21/TNFRSF11A/APP/IL18/CAMK2N1/TLR3/CEBPB/IL16/STAT5B/LPL/CD28/ZP3/TLR7/CD47/TNF/HLA-E/TNF/HLA-E/LTA/TNF/HLA-E/LTA/TNF/TNF/TNF/HLA-E/TNF/HLA-E/LTA/LTA/TNF/HLA-E/HLA-E/LTA/NEAT1/CEBPA/NAIP/NAIP/ABCC1/NAIP 64
GO:0051960 regulation of nervous system development 148/3662 428/15509 1.33328e-07 1.93055e-06 1.161e-06 KDM1A/TMEM98/IFRD1/PAFAH1B1/UFL1/HGF/TNFRSF1B/CDH1/NTN1/KDM4A/SIRT2/PLXNA2/PCM1/TP73/XRCC5/LRP2/ADNP/BMP7/TGFB1/PTN/EZH2/CXCL12/BMPR1A/DKK1/WNT3/EFNB3/CTSC/ZPR1/MDK/IFNG/DBN1/NPHP3/WNT5A/HES1/FN1/ID2/HDAC1/SPP1/CXCR4/EGR2/OBSL1/MYRF/IL1B/NKX2-2/BMP2/FLRT3/ID1/NR1D1/YWHAH/LIF/RARA/PER2/WASF3/EPHB2/KRAS/BHLHE40/NGF/LRP4/SERPINE2/IL6/DBNL/KIAA0319/SORL1/ACTR2/FGF2/CLSTN3/RB1/ST8SIA2/ITGAX/CRABP2/DUSP10/HES6/CTDSP1/SLIT2/TNFRSF21/TPBG/NTRK2/NOTCH1/PARD3/ITGB1/VEGFC/POU4F2/POU4F1/KIT/DPYSL5/SKI/FAIM/TBC1D24/DISC1/HEYL/ELAPOR2/SHH/GPER1/CDK5/CX3CR1/SEMA4C/RGS14/SEMA3E/LPAR3/MAP6/EIF2AK3/CCL11/RARG/DAG1/LIG4/BDNF/CDH4/F2/OXTR/PLAG1/ADGRB1/EPHB3/ANXA2/NOG/SS18L1/THBS2/NF2/DCC/IL1RAP/MME/SYNGAP1/MBP/NTRK1/MTOR/GPRASP3/TGM2/GDI1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/TWF2/SHANK3/CUX1/B2M/NEFL/WNT3/WNT3/PTEN 148
GO:0045661 regulation of myoblast differentiation 35/3662 65/15509 1.33625e-07 1.93055e-06 1.161e-06 ARID1B/ACTB/MBNL3/SMARCB1/CCL17/TGFB1/SMARCD2/PPARD/MAPK14/ARID1A/SOX4/FLOT2/BTG1/IGFBP3/NOTCH1/IL18/XKR8/RANBP3L/HIF1AN/BRD7/KAT5/DDIT3/PLCB1/ZFP36L1/ARID2/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SMARCB1 35
GO:1902893 regulation of miRNA transcription 35/3662 65/15509 1.33625e-07 1.93055e-06 1.161e-06 NGFR/SPI1/PDGFB/TGFB1/GATA3/BMPR1A/PPARD/MYB/FOXO3/EGR1/BMP2/RARA/IL10/SMAD6/FGF2/SMAD4/TERT/FOS/RELA/FOSL1/JUN/LILRB4/TEAD1/MRTFA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/LILRB4/LILRB4/LILRB4 35
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling 72/3662 174/15509 1.37206e-07 1.97768e-06 1.18934e-06 CASP10/MAP3K14/CD4/PPP5C/LTF/CD74/BIRC3/RHOA/DDX1/MID2/FKBP1A/MAVS/ABL1/CD40/VAPA/NDFIP2/UBE2I/EEF1D/NOD1/TRIM14/IL1A/FASLG/TNFRSF10B/TRIM25/TNFSF10/IL1B/RBCK1/CCR7/IRF3/AJUBA/EDA2R/NDFIP1/CC2D1A/TRIM5/TRIM22/CD36/TLR4/CCL21/PLK2/GJA1/TAB3/SHISA5/TLR3/NOD2/TRIM68/FADD/TNIP2/LGALS9/PRKCE/TRIM8/LURAP1/CCL19/RELA/TMEM9B/ADIPOQ/F2R/IRAK1/PRKN/ROR1/CARD9/MIB2/TNF/TRIM13/TNF/CHUK/TNF/TNF/TNF/TNF/TNF/TNF/IKBKG 72
GO:0051607 defense response to virus 101/3662 268/15509 1.41043e-07 2.02827e-06 1.21976e-06 MAP3K14/BIRC3/FOXP3/EIF2AK2/PUM2/HYAL2/DDX1/MID2/PTPRC/OPRK1/ZMPSTE24/ATG16L1/MAVS/IL12RB1/MARCHF2/CD40/RIOK3/TLR8/PYCARD/LILRB1/C1QBP/IFNG/AICDA/IL12B/IL4/STAT1/TNFAIP3/VAMP8/IFIT2/GPAM/TRIM25/IL1B/IRF3/BECN1/IRF5/TRAF3/TRIM5/TRIM22/POLR3F/SERINC3/PTPN22/IL6/TANK/NCBP1/DDX60/PPM1B/SENP7/HERC5/IL21/TARBP2/ITGAX/ARMC5/PMAIP1/LYST/NLRX1/POLR3K/CLPB/TLR3/MBL2/HTRA1/TRIM44/FADD/DDIT4/IRF2/POLR3D/TRIM56/TRIM8/BCL2L1/RELA/PDE12/PRF1/DDX60L/SETD2/MICA/IFITM1/CARD9/PLSCR1/TLR7/PCBP2/ATG7/ATAD3A/IFNA1/TRIM13/MICB/MICB/MICB/MICB/MICA/MICB/MICA/TRIM26/MICA/MICB/IL10RB/LSM14A/PTPRC/LILRB1/LILRB1/LILRB1/LILRB1/ITCH 101
GO:0051384 response to glucocorticoid 59/3662 134/15509 1.42474e-07 2.04411e-06 1.22929e-06 BAD/CPS1/PTPRU/RHOA/PCK2/PLAT/GSK3A/RPS6KB1/AREG/CCND1/MDK/IGFBP2/SDC1/ARG1/FOXO3/KLF9/FLT3/FOSB/ZFP36/CDO1/EPO/ASS1/IL6/IL10/IL1RN/CYP1B1/IGF1R/SLIT2/ALAD/ZFP36L2/BCL2L11/BMP6/STC1/CALM3/CASP3/ABCA3/DDIT4/ADAM9/PTAFR/FOS/FOSL1/A2M/TYMS/SSTR2/ADIPOQ/PAPPA/SLIT3/ZFP36L1/UBE2L3/WNT7B/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEFL 59
GO:0050869 negative regulation of B cell activation 23/3662 35/15509 1.42839e-07 2.0446e-06 1.22959e-06 BTK/TYROBP/HMGB3/PARP3/FOXP3/FCGR2B/SFRP1/BCL6/ID2/TNFAIP3/INHBA/PKN1/FOXJ1/NDFIP1/IL10/TNFRSF21/CTLA4/CASP3/INPP5D/CR1/TNFRSF13B/INPP5D/PTEN 23
GO:0002765 immune response-inhibiting signal transduction 18/3662 24/15509 1.49973e-07 2.14178e-06 1.28803e-06 LILRB1/CD33/LILRB4/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 18
GO:0006913 nucleocytoplasmic transport 108/3662 292/15509 1.60882e-07 2.27304e-06 1.36697e-06 UPF1/POLA2/RANBP3/CDH1/THOC3/TNPO3/IPO5/ELAVL1/SP100/HYAL2/SMG6/PRKACA/SIRT6/GSK3B/XPO1/TNPO1/SEH1L/IPO11/MAVS/ALKBH5/NUP50/HSP90AB1/RANGAP1/PABPN1/NFKBIA/FERMT1/NXT2/KPNA3/AXIN1/TSC2/UBE2I/TGFB1/TNPO2/CASC3/RANGRF/ZPR1/IFNG/MAPK14/HSPA9/KPNA1/PARK7/NRDE2/TARDBP/CRY2/EGR2/CSE1L/CDKN1A/NUP153/NUP85/IL1B/NUP210/NXT1/XPO4/IPO8/CD36/MDFIC/AKIRIN2/HNRNPA1/LTV1/NCBP1/ANP32B/ANP32A/EIF4A3/POLR2D/PIK3R1/NOTCH1/TCF7L2/BAG3/HHEX/RANBP2/HEATR3/APPL1/LMNA/NXF1/THOC7/PRKCD/RANBP3L/SHH/CDK5/SYK/NEMF/CHP2/AHCYL1/PKIG/DDX19A/RGS14/NMD3/CDK1/LEP/CALR/PTPN11/NPM1/SETD2/PTTG1IP/XPOT/IPO4/SDAD1/IPO9/SMG5/SARNP/IPO7/EIF6/RBM15B/RBM8A/TXNIP/SQSTM1/IPO4/PRKACA 108
GO:0051169 nuclear transport 108/3662 292/15509 1.60882e-07 2.27304e-06 1.36697e-06 UPF1/POLA2/RANBP3/CDH1/THOC3/TNPO3/IPO5/ELAVL1/SP100/HYAL2/SMG6/PRKACA/SIRT6/GSK3B/XPO1/TNPO1/SEH1L/IPO11/MAVS/ALKBH5/NUP50/HSP90AB1/RANGAP1/PABPN1/NFKBIA/FERMT1/NXT2/KPNA3/AXIN1/TSC2/UBE2I/TGFB1/TNPO2/CASC3/RANGRF/ZPR1/IFNG/MAPK14/HSPA9/KPNA1/PARK7/NRDE2/TARDBP/CRY2/EGR2/CSE1L/CDKN1A/NUP153/NUP85/IL1B/NUP210/NXT1/XPO4/IPO8/CD36/MDFIC/AKIRIN2/HNRNPA1/LTV1/NCBP1/ANP32B/ANP32A/EIF4A3/POLR2D/PIK3R1/NOTCH1/TCF7L2/BAG3/HHEX/RANBP2/HEATR3/APPL1/LMNA/NXF1/THOC7/PRKCD/RANBP3L/SHH/CDK5/SYK/NEMF/CHP2/AHCYL1/PKIG/DDX19A/RGS14/NMD3/CDK1/LEP/CALR/PTPN11/NPM1/SETD2/PTTG1IP/XPOT/IPO4/SDAD1/IPO9/SMG5/SARNP/IPO7/EIF6/RBM15B/RBM8A/TXNIP/SQSTM1/IPO4/PRKACA 108
GO:1905897 regulation of response to endoplasmic reticulum stress 40/3662 79/15509 1.6091e-07 2.27304e-06 1.36697e-06 MBTPS2/UFL1/BAK1/HSPA5/HERPUD1/ATXN3/FCGR2B/PPP1R15A/BAX/BAG6/XBP1/USP14/BFAR/SGTA/CREB3/TMEM33/PARK7/CLU/SERINC3/TMBIM6/PMAIP1/MANF/PIK3R1/BCL2L11/USP25/PPP1R15B/BCL2L1/EIF2AK3/DDIT3/PTPN2/ERN1/GRINA/PRKN/SVIP/BAG6/MAGEA3/BAG6/BAG6/BAG6/BAG6 40
GO:0001915 negative regulation of T cell mediated cytotoxicity 17/3662 22/15509 1.60998e-07 2.27304e-06 1.36697e-06 FCGR2B/PTPRC/LILRB1/PPP3CB/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/PTPRC/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1 17
GO:0002767 immune response-inhibiting cell surface receptor signaling pathway 17/3662 22/15509 1.60998e-07 2.27304e-06 1.36697e-06 LILRB1/LILRB4/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 17
GO:0071801 regulation of podosome assembly 16/3662 20/15509 1.62299e-07 2.28621e-06 1.37489e-06 RHOA/HCK/IL5/LCP1/MSN/GSN/CSF2/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 16
GO:0045786 negative regulation of cell cycle 128/3662 360/15509 1.63893e-07 2.30342e-06 1.38524e-06 CRY1/BAZ1B/RUNX3/FHL1/YTHDC2/USP28/RAD51/IPO5/NDC80/ATRX/ZW10/BIRC5/CDC6/MSH2/ABL1/BMP7/RBBP8/NUBP1/NBN/DOT1L/LILRB1/TGFB1/CASP2/EZH2/GATA3/RNF167/CCL2/CCND1/FBXO5/MAPK14/CCNG1/RAD50/MACROH2A1/BCL6/KAT2B/ZBTB17/CDC20/TNFAIP3/PKD2/TEX14/INHBA/NR4A1/CDKN1A/BMP2/LIF/CDKN1C/BTG1/MEN1/CCNB1/CDCA8/APC/IL10/NABP2/BRCA2/RB1/CUL4A/DTL/TP53BP2/INTS3/RHOB/CTDSP1/PLK2/SPC25/ZFP36L2/HHEX/SMARCA5/XPC/EME1/BTG2/PRMT2/BRSK1/MRNIP/RPL26/CASP3/GPER1/CDK5/BRD7/WEE1/RFWD3/BUB1/AVEN/CDK1/TRIAP1/RHNO1/NABP1/ZWILCH/ANGEL2/CTDSP2/AURKAIP1/AURKB/PTPN11/NPM1/CACNB4/CEP63/CHEK2/FOXO4/MUC1/ZFP36L1/HEXIM1/H2AX/KANK2/GIGYF2/TNF/HLA-G/IPO7/TNF/HLA-G/SIPA1/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/CEBPA/PRKDC/CDKN1C/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1/PTEN 128
GO:0009314 response to radiation 145/3662 419/15509 1.69198e-07 2.3726e-06 1.42684e-06 KDM1A/CRY1/SNAI2/BAK1/HSPA5/USP28/PER3/FOXP3/RAD51/CYBA/PRDM1/TMEM161A/KARS1/HYAL2/SMC1A/SIRT6/UBE2A/XRCC5/PTPRC/OPRK1/ZMPSTE24/RAD54L/BAX/MMP2/ANGPT2/MSH2/CIRBP/MMP9/ACTR5/N4BP1/NDRG4/EYA1/SFRP1/EEF1D/ERCC2/HAMP/BRAT1/GATA3/CXCL12/MAPK8/UNC119/CRYAB/B3GAT1/CCND1/PITPNM1/MAPK14/PDE8B/IL12B/IL1A/ID2/GADD45A/DNMT3A/EGR1/CRY2/CAT/CDKN1A/ELK1/FBXL12/GNGT1/PER2/PRKAA1/KRAS/MEN1/BHLHE40/DDB2/NMT1/TANK/XPA/NABP2/BRCA2/CUL4A/TNFRSF11A/APP/DTL/INTS3/PARP1/RHOB/PIK3R1/EGFR/TLK2/ALAD/ITGB1/NMT2/XPC/GNAQ/KIT/CUL4B/NR2F6/BRSK1/MRNIP/RPL26/VCAM1/ERCC3/PRKCD/UVSSA/CASP3/CDK5/TP53INP1/RAG1/RFWD3/RGS14/FOS/MGMT/PPM1D/TRIAP1/BCL2L1/RHNO1/CCL11/KAT5/RELA/NABP1/LIG4/HRAS/GRIN1/GRB2/AURKB/NPM1/H2AC25/CACNB4/NOG/CHEK2/CCR4/H2AX/NOC2L/MME/MMP1/SYNGAP1/ELANE/NTRK1/TAFA2/FKBPL/TNF/TRIM13/TNF/FANCG/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/ITGB3/PTPRC/ELANE 145
GO:0140546 defense response to symbiont 101/3662 269/15509 1.74071e-07 2.43053e-06 1.46168e-06 MAP3K14/BIRC3/FOXP3/EIF2AK2/PUM2/HYAL2/DDX1/MID2/PTPRC/OPRK1/ZMPSTE24/ATG16L1/MAVS/IL12RB1/MARCHF2/CD40/RIOK3/TLR8/PYCARD/LILRB1/C1QBP/IFNG/AICDA/IL12B/IL4/STAT1/TNFAIP3/VAMP8/IFIT2/GPAM/TRIM25/IL1B/IRF3/BECN1/IRF5/TRAF3/TRIM5/TRIM22/POLR3F/SERINC3/PTPN22/IL6/TANK/NCBP1/DDX60/PPM1B/SENP7/HERC5/IL21/TARBP2/ITGAX/ARMC5/PMAIP1/LYST/NLRX1/POLR3K/CLPB/TLR3/MBL2/HTRA1/TRIM44/FADD/DDIT4/IRF2/POLR3D/TRIM56/TRIM8/BCL2L1/RELA/PDE12/PRF1/DDX60L/SETD2/MICA/IFITM1/CARD9/PLSCR1/TLR7/PCBP2/ATG7/ATAD3A/IFNA1/TRIM13/MICB/MICB/MICB/MICB/MICA/MICB/MICA/TRIM26/MICA/MICB/IL10RB/LSM14A/PTPRC/LILRB1/LILRB1/LILRB1/LILRB1/ITCH 101
GO:0051222 positive regulation of protein transport 104/3662 279/15509 1.74114e-07 2.43053e-06 1.46168e-06 BAD/CD38/IGF1/CASR/CDH1/NNAT/IPO5/HYAL2/VPS35/CSNK2A2/PRKACA/SIRT6/PCM1/GSK3B/OXCT1/ACHE/DNM1L/MAVS/P2RX7/HSP90AB1/SH3GLB1/GZMB/PCK2/PARD6A/KCNN4/PDCD5/TGFB1/CD33/GSK3A/MAPK8/PPP3CB/ZPR1/CD81/PSMD9/IFNG/PPARD/MAPK14/TMEM30A/APBB3/IL1A/SERP1/TARDBP/ACSL3/SOX4/IL1B/ERGIC3/RAC2/PRKAA1/XPO4/GLUL/NMT1/TLR4/ANP32B/SORL1/CEP131/SAE1/PIK3R1/GLUD1/TCF7L2/VEGFC/BAG3/BMP6/ITGB2/PCNT/BAP1/PRKCD/SHH/GPER1/CDK5/CHP2/ADAM9/MFF/ITGAM/CDK1/PRKCE/FGG/FGA/LEP/HRAS/PDZK1/ATG13/CDK5R1/MIEF2/CIB1/UBE2L3/CLN3/PPIA/SRC/UBL5/HSPA1L/TNF/HSPA1L/TNF/FIS1/TNF/HSPA1L/TNF/TNF/TNF/TNF/TNF/HSPA1L/HSPA1L/PRKACA 104
GO:0055072 iron ion homeostasis 41/3662 82/15509 1.76675e-07 2.46075e-06 1.47985e-06 HFE/LTF/SLC11A1/HYAL2/ATP6AP1/PICALM/SLC46A1/FTL/SLC22A17/NUBP1/SLC39A14/HAMP/TFR2/HPX/SLC11A2/IFNG/RHAG/ATP6V1A/EPAS1/FBXL5/NDFIP1/ISCU/IREB2/ATP6V1G1/SMAD4/SOD1/SLC25A37/LCN2/BMP6/STEAP2/ALAS2/CYB561A3/MELTF/FXN/EPB42/FTH1/ERFE/BTBD9/TMPRSS6/TMEM199/B2M 41
GO:0070664 negative regulation of leukocyte proliferation 48/3662 102/15509 1.78674e-07 2.48301e-06 1.49324e-06 BTK/TYROBP/FOXP3/FCGR2B/ARG2/LILRB1/BCL6/CD86/TNFAIP3/ARG1/CD80/PKN1/TWSG1/FOXJ1/NDFIP1/SFTPD/IL2RA/IL10/TNFRSF21/CTLA4/CASP3/SHH/INPP5D/LGALS9/CEBPB/GLMN/LILRB4/PDCD1LG2/CR1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/TNFRSF13B/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D/PTEN/ITCH 48
GO:0002762 negative regulation of myeloid leukocyte differentiation 29/3662 50/15509 1.87811e-07 2.59254e-06 1.55911e-06 LTF/SFRP1/LILRB1/IL4/IAPP/INHBA/LRRC17/RARA/PIAS3/TLR4/CUL4A/TCTA/PIK3R1/TLR3/TNFRSF11B/INPP5D/GPR137/PTPN2/ADIPOQ/LILRB4/MAFB/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/INPP5D 29
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT 29/3662 50/15509 1.87811e-07 2.59254e-06 1.55911e-06 PIBF1/IL12B/IL4/IL5/HES1/PTK2B/IL6/IL10/CYP1B1/NOTCH1/KIT/ADIPOR1/IL6R/LEP/F2/F2R/SOCS1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL10RB/GH1/CCL5/CCL5 29
GO:1902895 positive regulation of miRNA transcription 29/3662 50/15509 1.87811e-07 2.59254e-06 1.55911e-06 NGFR/SPI1/PDGFB/TGFB1/GATA3/BMPR1A/MYB/FOXO3/EGR1/BMP2/IL10/SMAD6/FGF2/SMAD4/TERT/FOS/RELA/FOSL1/JUN/TEAD1/MRTFA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 29
GO:0002369 T cell cytokine production 27/3662 45/15509 1.89394e-07 2.60281e-06 1.56528e-06 HFE/TNFRSF1B/FOXP3/TBX21/SMAD7/CLC/GATA3/CD81/IL4/ARG1/IL1B/IL6/IL18/LILRB4/CD55/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/B2M/LILRB4/LILRB4/LILRB4 27
GO:0002724 regulation of T cell cytokine production 27/3662 45/15509 1.89394e-07 2.60281e-06 1.56528e-06 HFE/TNFRSF1B/FOXP3/TBX21/SMAD7/CLC/GATA3/CD81/IL4/ARG1/IL1B/IL6/IL18/LILRB4/CD55/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/B2M/LILRB4/LILRB4/LILRB4 27
GO:0001101 response to acid chemical 55/3662 123/15509 2.00325e-07 2.74694e-06 1.65196e-06 BAD/UFL1/CPS1/RRAGD/CYBA/F7/ATP2B4/IPO5/RHOA/MMP2/XBP1/RPS6KB1/LAMTOR3/ARG1/PKD2/DNMT3A/BCL2L2/CDO1/ASS1/SESN2/DNMT1/PDGFRA/TMBIM6/IGF1R/MEAK7/PDGFC/EGFR/NTRK2/ALAD/ZEB1/SESN3/CAPN2/CASP3/CYBB/NSMF/BCL2L1/CEBPB/GRIN1/SLC38A9/PLEC/NQO1/SOCS1/LAMTOR4/COL4A6/NTRK1/MTOR/TNF/TNF/SIPA1/TNF/TNF/TNF/TNF/TNF/TNF 55
GO:0010721 negative regulation of cell development 74/3662 182/15509 2.14816e-07 2.93266e-06 1.76365e-06 TMEM98/IFRD1/LTF/IGF1/CDH1/NTN1/KDM4A/SIRT2/FBLN1/PCM1/GSK3B/BMP7/LILRB1/GSK3A/PTN/BMPR1A/WNT3/EFNB3/CORO1C/WNT5A/HES1/IL1A/SPP1/IL1B/ID1/NR1D1/YWHAH/EPHB2/LRP4/EDNRB/IL6/KIAA0319/SORL1/RB1/DUSP10/CTDSP1/NOTCH1/NODAL/DPYSL5/SKI/DMTN/FRZB/MELTF/CDK5/SEMA4C/SEMA3E/CCL11/RCC2/F2/RFLNB/NOG/NF2/DCC/SPRY4/TRPV1/SYNGAP1/MBP/GDI1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/B2M/LILRB1/LILRB1/LILRB1/WNT3/WNT3/LILRB1/PTEN 74
GO:0032872 regulation of stress-activated MAPK cascade 74/3662 182/15509 2.14816e-07 2.93266e-06 1.76365e-06 WNT16/PAFAH1B1/NOX1/MAPK8IP2/HGF/FAS/FLT4/EIF2AK2/TRAF1/HIPK2/MAP2K4/SPI1/FCGR2B/TRAF4/OPRK1/MECOM/GADD45B/BIRC7/RASSF2/AXIN1/PYCARD/SFRP1/NOD1/FKTN/AMBP/FOXM1/WNT5A/IL1A/GADD45A/PRDX1/PTK2B/IL1B/BMP2/CCR7/PRMT1/EDA2R/TRAF3/MEN1/PTPN22/MDFIC/TLR4/CCL21/IGF1R/APP/DUSP10/ARL6IP5/EGFR/FOXO1/MBIP/TLR3/NOD2/SEMA4C/CCL19/LEP/HRAS/PLCB1/PRKN/CARD9/WNT7B/HMGB1/PPIA/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NAIP/ITCH 74
GO:0071496 cellular response to external stimulus 109/3662 297/15509 2.22538e-07 3.03141e-06 1.82304e-06 BAD/MAP3K14/SNAI2/GLRX2/RRAGD/FAS/BAK1/CASR/CLEC16A/HSPA5/CYBA/EIF2AK2/MAP2K4/ASNS/PTPRC/SEH1L/P2RX7/GCN1/COMT/SH3GLB1/XBP1/CD40/ADNP/TLR8/NPRL3/PIEZO1/SFRP1/TLE5/USF2/MTPN/CASP2/ENG/MAPK8/RNF167/HSPA8/FOLR1/CYP27B1/VDR/ITGA4/ELAPOR1/GADD45A/SLC2A1/FOXO3/TNFRSF10B/TNFRSF8/TRIM24/KCNJ2/CDKN1A/IL1B/MAX/BECN1/ATG14/CD68/SESN2/PRKAA1/MYBBP1A/HNRNPA1/GLUL/TTC5/TLR4/FGF2/GABARAPL1/IGF1R/TNFRSF11A/PMAIP1/SESN3/FOXO1/BAG3/BMP6/NR4A2/KLF10/WIPI2/ARHGAP35/BRSK1/WNT4/VCAM1/ATF3/INHBB/ALB/RICTOR/TLR3/AQP3/ZFYVE1/FADD/MN1/MAP3K2/FOS/PPM1D/EIF2AK3/KAT5/DAG1/BRSK2/LEP/LPL/FOSL1/PLEC/DCTPP1/GAS2L1/PRR5/AKR1C3/TLR7/KANK2/MAP3K5/ATG7/MTOR/SIPA1/ITGB3/PTPRC/LOC102724560 109
GO:0042509 regulation of tyrosine phosphorylation of STAT protein 39/3662 77/15509 2.26599e-07 3.07322e-06 1.84818e-06 IGF1/FGFR3/PIBF1/OSM/CD40/HPX/SH2B3/IFNG/IL12B/IL4/PPP2CA/HES1/FLT3/LIF/EPO/IL6/IL21/IL18/KIT/IL6R/IL24/IL3/CSF2/LEP/PTPN2/CSF1R/SOCS1/NF2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/CCL5/CCL5 39
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator 39/3662 77/15509 2.26599e-07 3.07322e-06 1.84818e-06 KDM1A/E2F2/CD74/CD44/USP28/HIPK2/TP63/TP73/BAX/MSH2/BAG6/PYCARD/DDX5/PERP/CDKN1A/DYRK2/EDA2R/MYBBP1A/BRCA2/PMAIP1/TP53BP2/POU4F2/POU4F1/ZNF385A/RPL26/SHISA5/DDIT4/HINT1/TRIAP1/PTTG1IP/CHEK2/PRKN/MUC1/BAG6/BAG6/BAG6/BAG6/BAG6/MIF 39
GO:1901222 regulation of NIK/NF-kappaB signaling 45/3662 94/15509 2.30709e-07 3.11711e-06 1.87457e-06 EIF2AK2/SPI1/RHOA/MKRN2/NFKBIA/BMP7/RASSF2/NFAT5/NOD1/IL12B/CD86/PRDX1/IL1B/RBCK1/PTPN22/TLR4/CCN3/PPM1B/APP/EGFR/IL18/NDUFC2/ADIPOR1/TLR3/TRIM44/NOD2/LGALS9/LIMS1/CD14/CCL19/RELA/CALR/IRAK1/PTP4A3/TLR7/TNF/TMSB4X/TNF/CPNE1/TNF/TNF/TNF/TNF/TNF/TNF 45
GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity 21/3662 31/15509 2.30841e-07 3.11711e-06 1.87457e-06 FGFR3/CDC42/EPHA8/PDGFB/FLT1/TGFB1/PDGFRB/TEK/PTK2B/FLT3/CCR7/ATG14/PDGFRA/CCL21/FGF2/KIT/NOD2/PTK2/CCL19/CD19/SRC 21
GO:0033157 regulation of intracellular protein transport 81/3662 205/15509 2.48779e-07 3.35202e-06 2.01585e-06 CDH1/IPO5/SP100/HYAL2/CSNK2A2/PRKACA/DERL2/LMAN1/SIRT6/PCM1/GSK3B/XPO1/MAVS/HSP90AB1/SH3GLB1/RANGAP1/GZMB/FERMT1/PDCD5/TGFB1/GSK3A/MAPK8/ZPR1/CD81/IFNG/MAPK14/TMEM30A/PARK7/TARDBP/IL1B/ERGIC3/RAC2/PRKAA1/XPO4/CD36/MDFIC/LCP1/NMT1/ANP32B/SORL1/CEP131/SAE1/PIK3R1/TCF7L2/BAG3/DMTN/ITGB2/PCNT/BAP1/PRKCD/SHH/CDK5/CHP2/PKIG/MFF/ITGAM/CDK1/BRSK2/LEP/HRAS/PDZK1/ATG13/CDK5R1/MIEF2/PTPN11/YOD1/ADIPOQ/CIB1/PRKN/UBE2L3/SVIP/UBL5/UBE2J1/GDI1/HSPA1L/HSPA1L/FIS1/HSPA1L/HSPA1L/HSPA1L/PRKACA 81
GO:0061138 morphogenesis of a branching epithelium 70/3662 170/15509 2.55196e-07 3.43103e-06 2.06336e-06 HOXA11/SNAI2/HGF/CASR/TIE1/FGFR2/TP63/GLI2/SIRT6/PGR/TMED2/ESR1/ABL1/BMP7/LAMA1/EYA1/SFRP1/TMEM59L/MET/HOXA5/ENG/AREG/MDK/VDR/WNT5A/KDM5B/PKD2/GNA13/BMP2/KDR/LAMA5/KRAS/SPRY2/NKX2-1/IL10/FGF2/EGF/GREB1L/SMAD4/EPHA2/SLIT2/ADAMTS16/NOTCH1/MMP14/WNT4/RBM15/TGFBR2/SHH/BTRC/FRS2/SEMA3E/CCL11/DAG1/GRB2/CTNNBIP1/NOG/CSF1/PBX1/SRC/NRARP/TGM2/FKBPL/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 70
GO:0010212 response to ionizing radiation 57/3662 130/15509 2.73701e-07 3.67186e-06 2.20819e-06 KDM1A/SNAI2/BAK1/HSPA5/USP28/RAD51/CYBA/KARS1/XRCC5/PTPRC/ZMPSTE24/RAD54L/BAX/MSH2/EYA1/SFRP1/EEF1D/HAMP/BRAT1/GATA3/CRYAB/CCND1/MAPK14/IL1A/GADD45A/DNMT3A/EGR1/CDKN1A/ELK1/PRKAA1/MEN1/TANK/NABP2/BRCA2/INTS3/PARP1/RHOB/TLK2/ALAD/MRNIP/RPL26/VCAM1/CASP3/RFWD3/MGMT/BCL2L1/RHNO1/KAT5/NABP1/LIG4/HRAS/GRB2/CHEK2/H2AX/TRIM13/PRKDC/PTPRC 57
GO:0002526 acute inflammatory response 52/3662 115/15509 2.76812e-07 3.70557e-06 2.22847e-06 BTK/FCGR2B/OSM/HAMP/PIK3CG/TFR2/GATA3/IL4/IL1A/FN1/PARK7/ASH1L/IL1B/C3/CCR7/EPO/ASS1/EDNRB/IL6/TNFRSF11A/IL6R/VCAM1/MBL2/CEBPB/A2M/CD163/CTNNBIP1/F2/CXCR2/SIGIRR/PLSCR1/ZP3/TRPV1/ELANE/TNF/HLA-E/TNF/HLA-E/TNF/HLA-E/TNF/TNF/TNF/HLA-E/ORM1/TNF/HLA-E/TNF/HLA-E/HLA-E/HP/ELANE 52
GO:0043406 positive regulation of MAP kinase activity 55/3662 124/15509 2.77927e-07 3.71249e-06 2.23262e-06 FGFR1/PTPRC/NOX4/P2RX7/PDGFB/CD40/FLT1/AXIN1/CSK/TGFB1/PIK3CG/EZH2/DKK1/MAP2K6/FZD10/PDGFRB/WNT5A/PTK2B/FLT3/IL1B/AJUBA/TLR4/THBS1/FGF2/EGF/MAP3K12/TNFRSF11A/PDGFC/EGFR/KIT/DVL3/SYK/NOD2/ADAM9/CCL19/HRAS/FZD4/ERN1/IRAK1/SRC/MAP3K5/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/PTPRC/CD24/MIF/ELANE 55
GO:0001666 response to hypoxia 103/3662 278/15509 2.80435e-07 3.73793e-06 2.24793e-06 BAD/CD38/CASR/CYBA/F7/HIPK2/RHOA/PDK3/SIRT2/MMP2/ALKBH5/ANGPT2/BMP7/SFRP1/PLAT/CXCL12/CRYAB/SLC11A2/PPARD/SLC29A1/IL1A/EPAS1/SLC2A1/MPL/FOXO3/PGF/DNMT3A/EGR1/PTK2B/CAT/CXCR4/BMP2/BECN1/PIN1/HP1BP3/GNGT1/AJUBA/CBFA2T3/EPO/PRKAA1/LOXL2/THBS1/TMBIM6/CYP1A1/SMAD4/PMAIP1/ARNT/PKLR/PSEN2/CCNA2/ALAD/NOTCH1/VEGFC/ITPR1/NR4A2/DDAH1/MMP14/ALAS2/STC1/LMNA/AK4/VCAM1/CAPN2/ERCC3/TGFBR2/FABP1/CASP3/TERT/CYBB/AQP3/HIF1AN/DDIT4/RBPJ/FOS/PRKCE/ARNT2/LEP/ADIPOQ/SLC8A1/IRAK1/ZFP36L1/P2RX2/SRC/DPP4/MTOR/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/ADSL/PKLR/CD24/LOC102724560/PTEN 103
GO:0051054 positive regulation of DNA metabolic process 102/3662 275/15509 3.0097e-07 3.99126e-06 2.40027e-06 DBF4/HGF/PARP3/ARID1B/RAD51/FAM168A/TMEM161A/MAP2K4/TBX21/GLI2/ACTB/MLH1/SIRT6/XRCC5/PTPRC/ATRX/NOX4/BAX/MAPKAPK5/FUS/MSH2/BRPF3/HSP90AB1/CDC7/BCL7C/SMARCB1/PDGFB/GINS1/CD40/RBBP8/EYA1/NBN/ERCC2/PRKD2/TGFB1/EXOSC3/SMARCD2/NSD2/BCL7A/FOXM1/EYA4/SMOC2/IL4/RAD50/PDGFRB/INO80D/ARID1A/SLF2/PTK2B/SHLD2/MORF4L2/USP9X/YEATS4/POT1/DKC1/HNRNPA1/CCT7/EPC2/IL6/CYP1B1/ACTR2/FGF2/EGF/NABP2/IGF1R/ARRB2/PARP1/EGFR/SMARCA5/CCDC117/MRNIP/DBF4B/TNFSF13/PRKCD/BRD7/CCT2/CDK1/MGMT/KAT5/KCTD13/CD28/AURKB/MAPK15/USP7/H2AX/ARID2/HMGB1/TRRAP/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/RTEL1/PTPRC/SMARCB1/TINF2 102
GO:0048302 regulation of isotype switching to IgG isotypes 12/3662 13/15509 3.01373e-07 3.99126e-06 2.40027e-06 FOXP3/TBX21/MLH1/PTPRC/MSH2/CD40/IL27RA/IL4/NDFIP1/SLC15A4/CD28/PTPRC 12
GO:1902565 positive regulation of neutrophil activation 12/3662 13/15509 3.01373e-07 3.99126e-06 2.40027e-06 ITGB2/PTAFR/ITGAM/TNF/CD177/TNF/TNF/TNF/TNF/TNF/TNF/TNF 12
GO:0032611 interleukin-1 beta production 45/3662 95/15509 3.38707e-07 4.46661e-06 2.68614e-06 TYROBP/IGF1/ARG2/P2RX7/TLR8/ACP5/MEFV/PYCARD/CD33/NOD1/HSPB1/IFNG/IL17A/WNT5A/TNFAIP3/EGR1/CCR7/CD36/IL6/TLR4/ARRB2/APP/GBP5/NOD2/CX3CR1/LGALS9/CCL19/LPL/F2R/LILRB4/TNF/TNF/TNF/TNF/TNF/TNF/ORM1/TNF/TNF/NAIP/LILRB4/NAIP/LILRB4/LILRB4/NAIP 45
GO:0032651 regulation of interleukin-1 beta production 45/3662 95/15509 3.38707e-07 4.46661e-06 2.68614e-06 TYROBP/IGF1/ARG2/P2RX7/TLR8/ACP5/MEFV/PYCARD/CD33/NOD1/HSPB1/IFNG/IL17A/WNT5A/TNFAIP3/EGR1/CCR7/CD36/IL6/TLR4/ARRB2/APP/GBP5/NOD2/CX3CR1/LGALS9/CCL19/LPL/F2R/LILRB4/TNF/TNF/TNF/TNF/TNF/TNF/ORM1/TNF/TNF/NAIP/LILRB4/NAIP/LILRB4/LILRB4/NAIP 45
GO:0030101 natural killer cell activation 46/3662 98/15509 3.51343e-07 4.6234e-06 2.78043e-06 TYROBP/SLAMF7/PRDM1/PTPRC/PIBF1/HECTD1/BAG6/ELF4/IL21R/GATA3/IL12B/PRDX1/CD244/ULBP2/PTPN22/SNX27/IL18/MERTK/STAT5B/LEP/MICA/PBX1/BLOC1S3/IFNA1/BAG6/HLA-E/HLA-E/NCR3/HLA-E/NCR3/BAG6/HLA-E/BAG6/HLA-E/MICA/MICA/BAG6/HLA-E/BAG6/MICA/NCR3/HLA-E/NCR3/NCR3/NCR3/PTPRC 46
GO:0019058 viral life cycle 105/3662 286/15509 3.61656e-07 4.74903e-06 2.85598e-06 CD4/LTF/CD74/YTHDC2/EIF2AK2/HYAL2/MID2/ATG16L1/CHMP5/MAVS/CCNK/ICAM1/HSP90AB1/SMARCB1/CHMP4B/VAPA/KPNA3/N4BP1/SLC1A5/TRIM14/CCL2/EFNB3/HSPA8/DDX6/CD81/AICDA/CD86/SPCS1/NR5A2/VAMP8/TRIM25/CD80/CXCR4/STAU1/NUP153/DEK/NECTIN2/APOE/CHMP1A/TOP2A/TRIM5/TRIM22/ARL8B/SRPK2/ITGAV/SLC7A1/TARBP2/FURIN/EPHA2/EGFR/GSN/NOTCH1/NCAM1/HMGA2/ITGB1/NMT2/EEF1A1/CTBP1/CCR5/VCP/ANPEP/TRIM68/SLC3A2/ATG16L2/LGALS9/CXCL8/GYPA/PDCD6IP/CDK1/TRIM8/BSG/DAG1/PDE12/CTBP2/BANF1/CHMP6/TMEM39A/CD28/CIITA/PRKN/SLC52A2/IFITM1/PLSCR1/HMGB1/PPIA/CD55/PCBP2/DPP4/WWP2/CR1/TNF/TNF/ZBED1/TNF/TNF/TNF/TNF/TNF/TNF/TRIM26/ITGB3/CCL5/CCL5/SMARCB1/ITCH 105
GO:0030522 intracellular receptor signaling pathway 93/3662 246/15509 3.68931e-07 4.83433e-06 2.90728e-06 KDM1A/CRY1/RNF14/UFL1/SNAI2/BIRC3/PUM2/PLPP1/RHOA/PDK3/TP63/PIAS2/PGR/ESR1/RBFOX2/NFKBIA/RIOK3/SFRP1/EZH2/AHR/ZMIZ1/C1QBP/DDX5/MAP2K6/CYP27B1/VDR/PPARD/KDM3A/PARK7/HDAC1/NR5A2/PADI2/ARID1A/TNFAIP3/NR4A3/CRY2/TRIM24/PKN1/NR4A1/CNOT1/BMP2/THRA/NR1D1/IRF3/YWHAH/ALDH1A2/RARA/WBP2/PTPN22/TLR4/DDX60/SLC15A4/CARM1/ARNT/PARP1/CNOT9/THRB/POU4F2/NR4A2/NODAL/NR2F6/PRMT2/NLRX1/ALOX15/CLPB/HEYL/GPER1/NOD2/TRIM68/MN1/TADA3/CYP7B1/RARG/RELA/ESRRA/LEP/CTBP2/TAF7/CALR/LACC1/PRAME/AKR1C3/SRC/KANK2/RXRB/DAXX/DAXX/DAXX/DAXX/DAXX/LSM14A/PAGR1/ITCH 93
GO:0090068 positive regulation of cell cycle process 86/3662 223/15509 3.73493e-07 4.88377e-06 2.93701e-06 CDC27/KMT2E/DBF4/PAF1/IGF1/SPAST/RHOA/SIRT2/CDC42/SPAG5/NDC80/ATRX/NSFL1C/ANAPC5/BIRC5/CDC6/CDC7/PDGFB/APEX1/CDC25B/RAB11A/EZH2/CCND1/FBXO5/CCND3/MACROH2A1/PDGFRB/SMC4/KAT2B/WNT5A/IL1A/SLF2/IL1B/BECN1/HSPA2/SOX15/CCNB1/CDCA8/NUMA1/RDX/NUSAP1/KIF23/EGF/RB1/CUL4A/IGF1R/CYP1A1/APP/DTL/DYRK3/PKP4/EGFR/NCAPG2/ADAMTS1/LSM11/CUL4B/CXCR5/DBF4B/WNT4/TERT/RRM1/CDK1/PRKCE/RHNO1/RRM2/KAT5/CD28/AURKB/RCC2/MAPK15/NPM1/PLCB1/CHEK2/CDK10/PBX1/PLSCR1/TFDP1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PAGR1 86
GO:0022411 cellular component disassembly 145/3662 424/15509 3.77202e-07 4.9219e-06 2.95994e-06 UPF1/SCIN/PAFAH1B1/UFL1/SNAI2/SPAST/CLEC16A/PHF23/VMP1/NAV3/TBC1D25/SPTB/CSNK2A2/WDR1/MARK2/NSF/ADD2/ACTN2/GSK3B/ZMPSTE24/CHMP5/BAX/MMP2/ADD1/DNM1L/TPX2/SUPT16H/SNAP29/MMP11/CECR2/SMARCB1/TFIP11/CTSG/ACIN1/MMP9/CHMP4B/TSC2/TGFB1/GSK3A/MTPN/TGFBR1/DKK1/SMARCD2/HSPA8/NEDD9/PARK7/CAPZA1/MFN2/STMN1/ARID1A/VAMP8/MTRF1/LRP1/C3/DSTN/BECN1/ATG14/HSPA2/CHMP1A/TOP2A/PRKAA1/APC/SNX14/MICAL1/LAMC1/LCP1/IL6/HMGA1/MMP7/RDX/GABARAPL1/IGF1R/FURIN/RETREG3/SH3GL1/KIF2C/DYRK3/SNAPIN/PIK3R1/OGT/GSN/MRRF/SSRP1/PLEKHH2/PRKCA/SCAF4/MMP14/WIPI2/DMTN/ADAMTS4/SPTBN4/SPTA1/FYCO1/MELTF/SLC25A46/GPER1/CDK5/VCP/FUNDC2/MAPRE2/GOLGA2/DDIT4/CX3CR1/ADRB2/ITGAM/CDK1/KIF5B/CFL1/KAT5/SPTBN2/ATP2A2/ATG13/CHMP6/TMEM39A/PLAAT3/FLII/H2AC25/CIB1/PRKN/TMPRSS6/CLN3/ARID2/RRP7A/MMP1/ATG7/ELANE/DPP4/SPTAN1/IQANK1/TNF/RIMOC1/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/PDXP/TWF2/LIX1L/SMARCB1/ELANE/SQSTM1 145
GO:0010720 positive regulation of cell development 107/3662 293/15509 3.79825e-07 4.94571e-06 2.97426e-06 BAD/KDM1A/HOXA11/PAFAH1B1/TYROBP/UFL1/TNFRSF1B/NTN1/SIRT2/CDC42/PLXNA2/TP73/XRCC5/LRP2/ADD1/ABL1/ADNP/SMAD7/OLFM4/TGFB1/PTN/CXCL12/WNT3/C1QBP/MDK/IFNG/NEDD9/IL5/DBN1/HES1/FN1/ID2/HDAC1/MPL/CXCR4/EGR2/OBSL1/IL1B/NKX2-2/BMP2/LIF/EPHB2/KRAS/NGF/SERPINE2/IL6/DBNL/ACTR2/FGF2/CRABP2/SLIT2/NTRK2/NOTCH1/ITGB1/VEGFC/POU4F2/KIT/FAIM/DMTN/TBC1D24/DISC1/SLC9B2/SHH/GPER1/CX3CR1/RGS14/LIMS1/LPAR3/MAP6/FGG/FGA/PDE3A/DAG1/LIG4/BDNF/CALR/CDH4/ADIPOQ/PLAG1/SS18L1/CIB1/MME/MTOR/GPRASP3/TGM2/GDI1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/TWF2/SHANK3/PRKDC/CUX1/ITGB3/NEFL/WNT3/WNT3 107
GO:0035303 regulation of dephosphorylation 55/3662 125/15509 3.83165e-07 4.97873e-06 2.99412e-06 PTBP1/MTMR1/ROCK1/SMG6/PTPRC/GSK3B/PPP1R15A/FKBP1A/HSP90AB1/PPP6R2/PPP1R16B/URI1/TGFB1/CD33/IFNG/PPP2R5D/PDGFRB/PTPA/MASTL/CRY2/BMP2/PIN1/STYXL1/ENSA/CALM2/BOD1/GNA12/SPPL3/PPP1R15B/CALM3/PRKCD/NSMF/CHP2/ANKLE2/PPP1R2/MAGI2/PPIA/SRC/MTOR/SMG5/CSNK2B/TNF/PPP1R11/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PTPRC 55
GO:0034968 histone lysine methylation 51/3662 113/15509 3.85875e-07 5.00346e-06 3.00899e-06 NFYA/KDM1A/KMT2E/ARID4B/KDM4A/NFYC/ATRX/DNMT3B/SMARCB1/SETD6/DOT1L/EZH2/GATA3/EZH1/NSD2/HCFC2/MACROH2A1/KDM3A/ASH1L/MYB/PHF19/H1-3/ASH2L/PRDM12/DNMT1/MEN1/SKIC8/SMAD4/BOD1/OGT/NSD3/LMNA/GFI1/PYGO2/NSD1/NNMT/SETD5/H1-4/HCFC1/TRMT112/SETD2/SETD3/KMT5A/TET3/H1-2/PAX5/WDR5/WDR5B/NCOA6/SMARCB1/PAGR1 51
GO:0038061 NIK/NF-kappaB signaling 53/3662 119/15509 3.87431e-07 5.01314e-06 3.01482e-06 MAP3K14/BIRC3/EIF2AK2/SPI1/RHOA/MKRN2/TRAF4/NFKBIA/BMP7/RASSF2/NFAT5/NOD1/IL12B/CD86/PRDX1/TNFRSF10B/IL1B/RBCK1/CHI3L1/PTPN22/TLR4/CCN3/PPM1B/APP/EGFR/PPP4C/IL18/NDUFC2/ADIPOR1/TLR3/TRIM44/NOD2/LGALS9/LIMS1/CD14/ALK/CCL19/RELA/CALR/IRAK1/PTP4A3/TLR7/TNF/TMSB4X/TNF/CHUK/CPNE1/TNF/TNF/TNF/TNF/TNF/TNF 53
GO:0002888 positive regulation of myeloid leukocyte mediated immunity 18/3662 25/15509 4.1682e-07 5.371e-06 3.23002e-06 BTK/TYROBP/SPI1/DDX1/MAVS/ARG1/C3/ITGB2/PTAFR/ITGAM/HLA-E/CD177/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 18
GO:2000353 positive regulation of endothelial cell apoptotic process 18/3662 25/15509 4.1682e-07 5.371e-06 3.23002e-06 CD40/CD40LG/CCL2/ITGA4/CD160/FASLG/FOXO3/THBS1/GPER1/AKR1C3/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 18
GO:0018205 peptidyl-lysine modification 129/3662 369/15509 4.29152e-07 5.51844e-06 3.31869e-06 NFYA/KDM1A/KMT2E/MED24/BAZ1B/SNAI2/FOXP3/NNAT/ARID4B/KDM4A/NFYC/SPI1/SIRT2/MBD3/ACTB/PIAS2/ZMPSTE24/ATRX/ATXN7L3/DNMT3B/BRPF3/BAG6/SMARCB1/RASD2/RANGAP1/JADE3/SETD6/UBE2I/EYA1/DOT1L/EZH2/GATA3/ZMIZ1/EZH1/NSD2/NAA40/HCFC2/ZNF451/MACROH2A1/KAT2B/SF3B1/KDM3A/PARK7/ASH1L/DR1/MYB/PHF19/SLF2/EGR1/NAA50/EGR2/EEF1AKMT3/MORF4L2/SIRT5/H1-3/SOX4/DEK/RNF113A/YEATS4/LIF/ASH2L/PRDM12/DNMT1/PIAS3/PRKAA1/MYBBP1A/WBP2/MEN1/LOXL2/TAF5L/EPC2/IRF4/ATAT1/SENP7/BRCA2/SKIC8/SMAD4/FKBP10/SAE1/ARNT/BOD1/OGT/NSD3/KAT14/MBIP/SMARCA5/RANBP2/BRPF1/CTBP1/LMNA/TAF6L/GFI1/PYGO2/NSD1/BRD7/NNMT/SETD5/H1-4/HINT1/TADA3/HCFC1/KAT5/RELA/TRMT112/MSL2/TAF7/SETD2/SETD3/KMT5A/SUMO3/MUC1/TET3/H1-2/NOC2L/PAX5/WDR5/TRRAP/WDR5B/NCOA6/BAG6/ZBED1/BAG6/BAG6/BAG6/BAG6/SMARCB1/TADA2A/PCGF2/PAGR1 129
GO:0002876 positive regulation of chronic inflammatory response to antigenic stimulus 13/3662 15/15509 4.47414e-07 5.74135e-06 3.45275e-06 TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA 13
GO:0034284 response to monosaccharide 74/3662 185/15509 4.61367e-07 5.87726e-06 3.53448e-06 BAD/CASR/CYBA/RHOA/PDK3/PRKACA/OPRK1/OXCT1/NOX4/ICAM1/ANGPT2/SMARCB1/XBP1/PCK2/SLC39A14/PPP3CB/RPS6KB1/PPARD/SLC29A1/IL1A/FOXO3/EIF2B2/GPAM/EGR1/PTK2B/CAT/SOX4/RUNX2/NKX2-2/NR1D1/SESN2/PRKAA1/MEN1/GLUL/THBS1/KHK/IGF1R/SMAD4/COL6A2/PKLR/EPHA5/TCF7L2/TGFBR2/SLC9B2/CASP3/GPER1/CCDC186/PRKCE/NPTX1/KAT5/BRSK2/LEP/SMAD2/LPL/ERN1/RMI1/ADIPOQ/PLCB1/MAFA/SLC8A1/PIM3/SELENOT/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PKLR/TXNIP/SMARCB1/PRKACA 74
GO:0043405 regulation of MAP kinase activity 74/3662 185/15509 4.61367e-07 5.87726e-06 3.53448e-06 HYAL2/FGFR1/PTPRC/NOX4/P2RX7/PDGFB/CD40/BMP7/FLT1/AXIN1/CSK/SFRP1/TGFB1/PIK3CG/EZH2/DKK1/MAP2K6/SH2B3/FZD10/PDGFRB/WNT5A/PTK2B/FLT3/IL1B/BMP2/AJUBA/APOE/PTPN22/SPRY2/TLR4/SORL1/THBS1/FGF2/EGF/MAP3K12/TNFRSF11A/DUSP10/PDGFC/EGFR/UCHL1/KIT/DVL3/PRKCD/DUSP7/SYK/NOD2/CDK12/ADAM9/RGS14/CCL19/HRAS/FZD4/ERN1/ADIPOQ/IRAK1/HGS/SPRY4/SRC/MAP3K5/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/PTPRC/CD24/LOC102724560/MIF/ELANE 74
GO:0048754 branching morphogenesis of an epithelial tube 61/3662 144/15509 4.61799e-07 5.87726e-06 3.53448e-06 HOXA11/CASR/TIE1/FGFR2/GLI2/SIRT6/PGR/ESR1/ABL1/BMP7/LAMA1/EYA1/TMEM59L/MET/HOXA5/ENG/AREG/MDK/VDR/WNT5A/KDM5B/PKD2/GNA13/BMP2/KDR/LAMA5/KRAS/SPRY2/NKX2-1/FGF2/EGF/GREB1L/SMAD4/EPHA2/SLIT2/ADAMTS16/NOTCH1/MMP14/WNT4/RBM15/TGFBR2/SHH/BTRC/SEMA3E/CCL11/DAG1/CTNNBIP1/NOG/CSF1/PBX1/SRC/NRARP/FKBPL/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 61
GO:0090316 positive regulation of intracellular protein transport 61/3662 144/15509 4.61799e-07 5.87726e-06 3.53448e-06 CDH1/IPO5/HYAL2/CSNK2A2/PRKACA/SIRT6/PCM1/GSK3B/MAVS/HSP90AB1/SH3GLB1/GZMB/PDCD5/TGFB1/GSK3A/MAPK8/ZPR1/CD81/IFNG/MAPK14/TMEM30A/TARDBP/IL1B/ERGIC3/RAC2/PRKAA1/XPO4/NMT1/ANP32B/SORL1/CEP131/SAE1/PIK3R1/TCF7L2/BAG3/ITGB2/PCNT/BAP1/PRKCD/SHH/CDK5/CHP2/MFF/ITGAM/CDK1/LEP/HRAS/PDZK1/ATG13/CDK5R1/MIEF2/CIB1/UBE2L3/UBL5/HSPA1L/HSPA1L/FIS1/HSPA1L/HSPA1L/HSPA1L/PRKACA 61
GO:0006509 membrane protein ectodomain proteolysis 28/3662 49/15509 4.67615e-07 5.93909e-06 3.57166e-06 TNFRSF1B/ROCK1/P2RX7/MYH9/SH3D19/IFNG/IL1B/APOE/ADAM19/IL10/MMP7/FURIN/PSEN2/RBMX/ADAM9/DAG1/RGMA/PRTN3/TNF/PSENEN/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRTN3 28
GO:0009743 response to carbohydrate 82/3662 211/15509 4.76594e-07 6.04076e-06 3.6328e-06 BAD/CASR/CYBA/MAP2K4/RHOA/PDK3/PRKACA/OPRK1/OXCT1/APOB/NOX4/ICAM1/ANGPT2/SMARCB1/XBP1/PCK2/ADNP/SLC39A14/PPP3CB/RPS6KB1/MAP2K6/PPARD/SLC29A1/IL1A/FOXO3/EIF2B2/GPAM/EGR1/PTK2B/CAT/SOX4/RUNX2/IL1B/NKX2-2/NR1D1/SESN2/PRKAA1/MEN1/GLUL/THBS1/KHK/IGF1R/SMAD4/COL6A2/PKLR/EPHA5/TCF7L2/TGFBR2/SLC9B2/CASP3/GPER1/CCDC186/PRKCE/NPTX1/KAT5/BRSK2/LEP/SMAD2/LPL/ERN1/RMI1/NQO1/ADIPOQ/PLCB1/MAFA/SLC8A1/ZFP36L1/P2RX2/PIM3/SELENOT/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PKLR/TXNIP/SMARCB1/PRKACA 82
GO:0097305 response to alcohol 89/3662 234/15509 4.8044e-07 6.07707e-06 3.65464e-06 BAD/OSBPL7/BAK1/CDH1/H6PD/FOXP3/RAD51/CYBA/F7/FGFR2/RHOA/ST6GAL1/GNB1/OPRK1/OXCT1/SLC23A2/MLC1/SFRP1/TGFB1/HAMP/AHR/TGFBR1/GATA3/CSF3/RPS6KB1/RECQL5/CCND1/XRN1/FOXO3/KLF9/DNMT3A/CRHR1/PTK2B/CAT/INHBA/FOSB/CCR7/CDO1/CYP2E1/RARA/PRKAA1/CCL21/FDX1/CYP1B1/ACTR2/IGF1R/TNFRSF11A/SOD1/PARP1/SLIT2/ALAD/CALM3/CCR5/SCNN1D/VCAM1/INHBB/TGFBR2/ADCY1/TP53INP1/CYBB/CDK1/FOS/MGMT/CD14/PRKCE/BCL2L1/CCL19/DAG1/LEP/SMAD2/FOSL1/A2M/GRIN1/TYMS/NQO1/ADIPOQ/SLIT3/AKR1C3/RPL10A/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEFL/LRP6 89
GO:2000377 regulation of reactive oxygen species metabolic process 59/3662 138/15509 4.86696e-07 6.14199e-06 3.69369e-06 TYROBP/CYBA/RHOA/PDK3/SIRT2/ARG2/PDGFB/BMP7/ACP5/TGFB1/CRYAB/FOXM1/MAPK14/PDGFRB/PARK7/GADD45A/FOXO3/PTK2B/SIRT5/CDKN1A/BECN1/TRAP1/RAC2/CD36/TLR4/TFAP2A/THBS1/CYP1B1/SOD1/FOXO1/NDUFC2/ITGB2/TGFBR2/PRKCD/STK17A/SYK/PRDX2/ITGAM/SLC25A33/LEP/GRIN1/GRB2/F2/ADGRB1/PRKN/AKR1C3/SLC5A3/TNF/CD177/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/HP/AATF 59
GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation 26/3662 44/15509 4.87554e-07 6.14199e-06 3.69369e-06 FOXP3/IL4R/IL12RB1/CD81/IFNG/IL12B/CD86/CD160/MYB/CD80/RARA/HLX/IL2RG/IL18/TGFBR2/LGALS9/CCL19/CD28/KLHL25/SOCS1/CD55/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 26
GO:0070227 lymphocyte apoptotic process 38/3662 76/15509 4.937e-07 6.2068e-06 3.73266e-06 ST3GAL1/BTK/CD74/FAS/BAK1/ARG2/BAX/P2RX7/BIRC7/CLC/PRKD2/KDELR1/JAK3/BCL6/WNT5A/FASLG/GPAM/PKN1/BCL11B/IL2RA/IL10/TNFRSF21/BCL2L11/TSC22D3/RAG1/FADD/LGALS9/PRELID1/EFNA1/PTCRA/ORMDL3/AURKB/CHEK2/NOC2L/CCL5/CCL5/MIF/PTEN 38
GO:0046330 positive regulation of JNK cascade 46/3662 99/15509 5.07085e-07 6.36217e-06 3.8261e-06 WNT16/NOX1/FLT4/TRAF1/HIPK2/MAP2K4/FCGR2B/TRAF4/GADD45B/BIRC7/RASSF2/AXIN1/PYCARD/NOD1/WNT5A/IL1A/GADD45A/PTK2B/IL1B/CCR7/EDA2R/TRAF3/TLR4/CCL21/APP/MBIP/TLR3/NOD2/CCL19/HRAS/PLCB1/CARD9/WNT7B/HMGB1/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NAIP 46
GO:0051099 positive regulation of binding 66/3662 160/15509 5.14074e-07 6.43683e-06 3.871e-06 KDM1A/PON1/HFE/IGF1/HIPK2/SIRT2/ADD2/GSK3B/ADD1/FKBP1A/HSP90AB1/ABL1/MMP9/ERCC2/MED25/TGFB1/MET/EDF1/GATA3/CSF3/IFNG/PPP2CA/NPHP3/WNT5A/HES1/PARK7/STMN1/LRP1/USP9X/BMP2/PIN1/APOE/RARA/MEN1/NGF/NCBP1/DERL1/IRF4/EGF/RB1/APP/PARP1/CALM2/TCF7L2/POU4F2/POU4F1/ZNF618/SPPL3/SKI/EPB41/CALM3/PYGO2/SPTA1/TERT/CDK5/NMD3/CTBP2/BDNF/ANXA2/EIF3C/PRKN/H1-0/HMGB1/EBF2/NME1/B2M 66
GO:0070304 positive regulation of stress-activated protein kinase signaling cascade 56/3662 129/15509 5.17252e-07 6.46357e-06 3.88708e-06 WNT16/NOX1/MAPK8IP2/FLT4/EIF2AK2/TRAF1/HIPK2/MAP2K4/SPI1/FCGR2B/TRAF4/OPRK1/RNF13/GADD45B/BIRC7/RASSF2/AXIN1/PYCARD/NOD1/WNT5A/IL1A/GADD45A/PTK2B/IL1B/BMP2/CCR7/PRMT1/EDA2R/TRAF3/TLR4/CCL21/APP/ARL6IP5/MBIP/TLR3/NOD2/SEMA4C/CCL19/LEP/HRAS/PLCB1/CARD9/WNT7B/HMGB1/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NAIP 56
GO:0071383 cellular response to steroid hormone stimulus 76/3662 192/15509 5.30777e-07 6.54627e-06 3.93681e-06 KDM1A/CRY1/RNF14/UFL1/PLPP1/RHOA/TP63/PIAS2/PGR/ESR1/RBFOX2/PCK2/BMP7/SFRP1/PLAT/URI1/GSK3A/ZMIZ1/RPS6KB1/DDX5/HSPA8/PPARD/KDM3A/PARK7/HDAC1/PADI2/ARID1A/ARG1/FOXO3/KLF9/NR4A3/CRY2/FLT3/PKN1/CNOT1/NR1D1/ZFP36/YWHAH/ASS1/WBP2/CYP1B1/IGF1R/CARM1/PARP1/CNOT9/POU4F2/ZFP36L2/BCL2L11/NODAL/STC1/PRMT2/SCNN1D/ATP1A1/HEYL/GPER1/TRIM68/DDIT4/PAQR8/TADA3/CYP7B1/ESRRA/TAF7/CALR/SSTR2/ZFP36L1/UBE2L3/AKR1C3/SRC/KANK2/RXRB/DAXX/DAXX/DAXX/DAXX/DAXX/PAGR1 76
GO:0045667 regulation of osteoblast differentiation 54/3662 123/15509 5.31252e-07 6.54627e-06 3.93681e-06 LTF/IGF1/SNAI2/HGF/FGFR2/PRKACA/TP63/BMP7/RASSF2/SFRP1/BMPR1A/DDX5/AREG/FBXO5/SMAD5/RUNX2/BMP2/TWSG1/MEN1/IL6/SMAD6/FGF2/FBN2/TOB1/CCN1/NOTCH1/VEGFC/CRIM1/BMP6/SKI/IL6R/WNT4/RANBP3L/PTK2/RIOX1/CEBPB/ESRRA/FAM20C/CTNNBIP1/NOG/IFITM1/WNT7B/TNF/TNF/CEBPD/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/CRIM1/PRKACA 54
GO:0071803 positive regulation of podosome assembly 14/3662 17/15509 5.31259e-07 6.54627e-06 3.93681e-06 RHOA/IL5/LCP1/MSN/CSF2/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 14
GO:2001199 negative regulation of dendritic cell differentiation 14/3662 17/15509 5.31259e-07 6.54627e-06 3.93681e-06 FCGR2B/LILRB1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/HLA-G/LILRB1/LILRB1/LILRB1 14
GO:0035740 CD8-positive, alpha-beta T cell proliferation 16/3662 21/15509 5.31264e-07 6.54627e-06 3.93681e-06 PTPN22/HLA-E/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-A/HLA-E 16
GO:1902563 regulation of neutrophil activation 16/3662 21/15509 5.31264e-07 6.54627e-06 3.93681e-06 GRN/SPI1/FCGR2B/ITGB2/SYK/PTAFR/ITGAM/TNF/CD177/TNF/TNF/TNF/TNF/TNF/TNF/TNF 16
GO:2000564 regulation of CD8-positive, alpha-beta T cell proliferation 16/3662 21/15509 5.31264e-07 6.54627e-06 3.93681e-06 PTPN22/HLA-E/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-A/HLA-E 16
GO:0002514 B cell tolerance induction 10/3662 10/15509 5.3366e-07 6.54975e-06 3.9389e-06 FOXJ1/TGFBR2/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 10
GO:0060559 positive regulation of calcidiol 1-monooxygenase activity 10/3662 10/15509 5.3366e-07 6.54975e-06 3.9389e-06 IFNG/IL1B/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 10
GO:0042130 negative regulation of T cell proliferation 39/3662 79/15509 5.35234e-07 6.55608e-06 3.94271e-06 FOXP3/ARG2/LILRB1/CD86/ARG1/CD80/TWSG1/FOXJ1/NDFIP1/SFTPD/IL2RA/IL10/TNFRSF21/CTLA4/CASP3/SHH/LGALS9/CEBPB/GLMN/LILRB4/PDCD1LG2/CR1/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB1/LILRB4/HLA-G/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/PTEN/ITCH 39
GO:0009408 response to heat 52/3662 117/15509 5.38562e-07 6.58384e-06 3.9594e-06 IGF1/ATXN3/PRKACA/GSK3B/HSP90AB1/RBBP7/DNAJB6/HSPB1/CXCL12/RPS6KB1/CRYAB/CHORDC1/CALCA/IL1A/EIF2B2/HSPA2/THBS1/SOD1/PKLR/POLR2D/STAC/BAG3/CLPB/IER5/MAPKAPK2/NOS3/TP53INP1/VCP/CD14/MICA/IRAK1/TRPV1/MTOR/DAXX/DAXX/MICB/MICB/HSBP1L1/DAXX/MICB/DAXX/MICB/MICA/MICB/DAXX/MICA/MICA/MICB/PDCD6/PKLR/CHORDC1/PRKACA 52
GO:0019722 calcium-mediated signaling 78/3662 199/15509 6.02784e-07 7.35443e-06 4.42283e-06 SELE/CD4/BTK/PTBP1/CD22/IGF1/ATP2B4/ERBB3/PRKACA/PTPRC/GSK3B/P2RX5/ZMPSTE24/LAT2/P2RX7/NFATC2/NFAT5/PPP3CB/CCL20/ZAP70/FHL2/NR5A2/RCAN3/PTK2B/CXCR4/CCR7/DYRK2/KDR/TNNI3/PRKAA1/EDNRB/PLCE1/CALM2/ANK2/GSTO1/ITPR1/SPPL3/DMTN/CALM3/CXCR5/CCR5/VCAM1/CXCR1/SYK/CHP2/CX3CR1/CXCL8/HINT1/KSR2/EIF2AK3/RCAN2/CCR9/SELP/ATP2A2/GRIN1/CXCR2/SLC8A1/CCR4/CIB1/CXCR3/P2RX2/MTOR/TNF/TNF/STIMATE/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/P2RY11/PTPRC/CCL4/CCL4/CCL4/PRKACA 78
GO:0070098 chemokine-mediated signaling pathway 41/3662 85/15509 6.08762e-07 7.41278e-06 4.45791e-06 CCL22/CCL17/CXCL12/CCL2/SH2B3/CCL20/PADI2/MPL/GPR75/PTK2B/CXCR4/RNF113A/CCR7/CCL21/SLIT2/CXCL13/CXCR5/CCR5/RBM15/CXCR1/PF4/WBP1L/CX3CR1/CXCL8/CCL11/CCL19/CCR9/CXCR2/CCR4/SLIT3/CIB1/CXCR3/ACKR1/CCL5/CCL5/CCL4/CCL18/CCL4/CCL4/CCL18/CCL18 41
GO:2000107 negative regulation of leukocyte apoptotic process 32/3662 60/15509 6.10257e-07 7.41642e-06 4.4601e-06 ST3GAL1/CD74/ST6GAL1/ARG2/LILRB1/JAK3/CXCL12/BCL6/GPAM/CCR7/BCL11B/CCL21/MERTK/TSC22D3/RAG1/NOD2/FADD/EFNA1/BCL2L1/PTCRA/ORMDL3/CCL19/AURKB/CXCR2/NOC2L/CCL5/CCL5/LILRB1/LILRB1/MIF/LILRB1/LILRB1 32
GO:0050852 T cell receptor signaling pathway 61/3662 145/15509 6.15247e-07 7.46243e-06 4.48778e-06 BTN3A1/FOXP3/PTPRC/ABL1/CSK/KCNN4/PRKD2/GATA3/CD81/PDE4D/ZAP70/CD160/EIF2B2/RBCK1/CCR7/NECTIN2/PTPN22/TNFRSF21/CD8A/SPPL3/ICOSLG/CTLA4/BTNL9/INPP5D/RELA/HRAS/PTPN2/CD28/HLA-DQB1/CACNB4/PDE4B/BTN3A2/LILRB4/HLA-DQB1/HLA-DQB1/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-DQB1/HLA-DPB1/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/HLA-DPB1/HLA-DQB1/HLA-A/HLA-DQB1/HLA-DQB1/HLA-A/HLA-DPB1/HLA-DPB1/PTPRC/IKBKG/LILRB4/LILRB4/LILRB4/INPP5D 61
GO:0032388 positive regulation of intracellular transport 73/3662 183/15509 6.22866e-07 7.54009e-06 4.53448e-06 CDH1/IPO5/HYAL2/CSNK2A2/PRKACA/SPAG5/SIRT6/ACTN2/PCM1/GSK3B/MAVS/HSP90AB1/SH3GLB1/MLC1/GZMB/PDCD5/TGFB1/GSK3A/MAPK8/ZPR1/CD81/IFNG/MAPK14/TMEM30A/NRDE2/TARDBP/IL1B/ERGIC3/RAC2/PRKAA1/XPO4/NMT1/ANP32B/NUMA1/SORL1/RDX/CEP131/SAE1/SNAPIN/PIK3R1/MSN/TCF7L2/BAG3/LDLRAP1/ITGB2/PCNT/BAP1/PRKCD/SHH/CDK5/CHP2/MFF/ITGAM/CDK1/LEP/HRAS/PDZK1/ATG13/CDK5R1/MIEF2/ANXA2/CIB1/PRKN/UBE2L3/PGAP1/UBL5/HSPA1L/HSPA1L/FIS1/HSPA1L/HSPA1L/HSPA1L/PRKACA 73
GO:0050767 regulation of neurogenesis 124/3662 354/15509 6.34878e-07 7.67051e-06 4.61291e-06 KDM1A/TMEM98/IFRD1/PAFAH1B1/UFL1/TNFRSF1B/CDH1/NTN1/KDM4A/SIRT2/PLXNA2/PCM1/TP73/XRCC5/LRP2/ADNP/BMP7/TGFB1/PTN/EZH2/CXCL12/BMPR1A/WNT3/EFNB3/MDK/IFNG/DBN1/WNT5A/HES1/FN1/ID2/HDAC1/SPP1/CXCR4/EGR2/OBSL1/IL1B/NKX2-2/BMP2/ID1/NR1D1/YWHAH/LIF/PER2/EPHB2/KRAS/BHLHE40/NGF/LRP4/SERPINE2/IL6/DBNL/KIAA0319/SORL1/ACTR2/FGF2/RB1/CRABP2/DUSP10/HES6/CTDSP1/SLIT2/NTRK2/NOTCH1/ITGB1/VEGFC/POU4F2/POU4F1/KIT/DPYSL5/SKI/FAIM/TBC1D24/DISC1/HEYL/SHH/GPER1/CDK5/CX3CR1/SEMA4C/RGS14/SEMA3E/LPAR3/MAP6/CCL11/DAG1/LIG4/BDNF/CDH4/F2/PLAG1/ANXA2/NOG/SS18L1/NF2/DCC/MME/SYNGAP1/MBP/MTOR/GPRASP3/TGM2/GDI1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/TWF2/SHANK3/CUX1/B2M/NEFL/WNT3/WNT3/PTEN 124
GO:0036293 response to decreased oxygen levels 105/3662 289/15509 6.45556e-07 7.78435e-06 4.68137e-06 BAD/CD38/CASR/CYBA/F7/HIPK2/RHOA/PDK3/SIRT2/MMP2/ALKBH5/ANGPT2/BMP7/SFRP1/PLAT/CXCL12/CRYAB/SLC11A2/PPARD/SLC29A1/IL1A/EPAS1/SLC2A1/MPL/FOXO3/PGF/DNMT3A/EGR1/PTK2B/CAT/CXCR4/BMP2/BECN1/PIN1/HP1BP3/GNGT1/AJUBA/CBFA2T3/EPO/PRKAA1/LOXL2/THBS1/TMBIM6/BNIP2/CYP1A1/SMAD4/PMAIP1/ARNT/PKLR/PSEN2/CCNA2/ALAD/NOTCH1/VEGFC/ITPR1/NR4A2/DDAH1/MMP14/ALAS2/STC1/LMNA/AK4/VCAM1/CAPN2/ERCC3/TGFBR2/FABP1/CASP3/TERT/CYBB/AQP3/HIF1AN/DDIT4/RBPJ/FOS/PRKCE/ARNT2/LEP/OXTR/ADIPOQ/SLC8A1/IRAK1/ZFP36L1/P2RX2/SRC/DPP4/MTOR/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/ADSL/PKLR/CD24/LOC102724560/PTEN 105
GO:0010498 proteasomal protein catabolic process 155/3662 463/15509 6.61533e-07 7.96152e-06 4.78792e-06 CDC27/OSBPL7/RHBDF1/PSMB1/HFE/PSMC4/RNF14/UFL1/HSPA5/HERPUD1/RNF4/ATXN3/PSME4/SIRT2/SEL1L/PRKACA/FBXW11/DERL2/TBX21/MKRN2/TRAF4/SIRT6/UBE2A/UBE2K/PCNP/GSK3B/XPO1/PSMC5/NSFL1C/ANAPC5/PSME1/HECTD1/BAG6/HSP90AB1/PSMD8/XBP1/KCTD17/PSMC6/PSMA3/PSMA6/USP14/SMAD7/UGGT2/N4BP1/AXIN1/BFAR/SGTA/GSK3A/DVL1/ATE1/FBXW4/PSMD3/CCDC47/UBE4A/USP5/MAN1A1/SKP1/PARK7/CDC20/FBXL5/RAD23B/AREL1/CLU/TRIM25/USP9X/KLHDC3/RBCK1/NR1D1/FBXL12/CBFA2T3/APOE/ADRM1/PSME3/UBE2G1/FBXO44/HSPBP1/RNF122/APC/AKIRIN2/ECPAS/DERL1/FAM8A1/RNF121/CUL4A/ARRB2/CSNK1D/PMAIP1/DTL/SPOPL/FEM1C/GNA12/TLK2/OGT/ERLIN2/EIF3H/ALAD/DNAJB12/RNF144A/CLGN/UCHL1/FBXL18/USP25/UBXN11/CUL4B/ZFAND2B/PSMB4/PSMC2/SPSB3/WDR26/RYBP/PSMD6/RCHY1/SHH/TMUB1/VCP/NEMF/PSMC3/BTRC/UBXN6/RNF187/ENC1/SPSB1/KAT5/PSMD1/BRSK2/GLMN/KCTD13/PSMD2/DDIT3/CALR/YOD1/PRKN/PRAME/USP7/PCBP2/DDI2/SVIP/WWP2/UBE2J1/DCAF12/RNF5/BAG6/FBXO48/TRIM13/PSMB10/BAG6/BAG6/BAG6/BAG6/CEBPA/FBXO17/PSMB3/PRKACA/F8A1/ITCH 155
GO:0097242 amyloid-beta clearance 25/3662 42/15509 6.67238e-07 8.00183e-06 4.81216e-06 ROCK1/PICALM/LRP2/RAB11A/IFNG/IL4/HDAC1/CLU/LRP1/C3/APOE/LRP4/CD36/IGF1R/ITGB2/ITGAM/MME/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 25
GO:2000106 regulation of leukocyte apoptotic process 43/3662 91/15509 6.67465e-07 8.00183e-06 4.81216e-06 ST3GAL1/BTK/CD74/ST6GAL1/ARG2/BAX/P2RX7/BIRC7/LILRB1/PRKD2/JAK3/CXCL12/BCL6/WNT5A/GPAM/CCR7/BCL11B/IL10/CCL21/BCL2L11/MERTK/TSC22D3/RAG1/NOD2/FADD/LGALS9/PRELID1/EFNA1/BCL2L1/PTCRA/ORMDL3/CCL19/AURKB/CXCR2/NOC2L/CCL5/CCL5/LILRB1/LILRB1/MIF/LILRB1/LILRB1/PTEN 43
GO:0060252 positive regulation of glial cell proliferation 20/3662 30/15509 6.69547e-07 8.0113e-06 4.81785e-06 UFL1/NTN1/IL1B/KRAS/IL6/VEGFC/PLAG1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA 20
GO:0098727 maintenance of cell number 66/3662 161/15509 6.72248e-07 8.02812e-06 4.82797e-06 PAF1/IGF1/MED17/ARID4B/BICRA/ELAVL1/SPI1/SMC1A/TP63/ACTB/PCM1/KDM2B/BCL7C/MED15/SMARCB1/BMP7/RBBP7/SETD6/SFRP1/PTN/EZH2/BMPR1A/SMC3/DDX6/BCL7A/HES1/KDM3A/BCL9/PRRX1/HDAC1/ARID1A/FOXO3/PHF19/SOX4/CNOT1/LIF/MED6/LOXL2/TAF5L/TET1/CUL4A/OGT/NOTCH1/HMGA2/FOXO1/ZFP36L2/KLF10/NODAL/KIT/SKI/FANCC/PADI4/TAF6L/SELENON/RBBP4/SAP30/MED30/RBPJ/CDH2/TRIM8/LIG4/NOG/BCL9L/ZNF358/SMARCB1/PADI4 66
GO:0050851 antigen receptor-mediated signaling pathway 76/3662 193/15509 6.75321e-07 8.0493e-06 4.84071e-06 CD38/CD79B/BTK/CD22/BTN3A1/FOXP3/FCGR2B/PTPRC/LAT2/BAX/SPG21/ABL1/NFATC2/CSK/KCNN4/PRKD2/CD79A/GATA3/LPXN/CD81/PDE4D/ZAP70/CD160/EIF2B2/RBCK1/CCR7/NECTIN2/PTPN22/CMTM3/TNFRSF21/CD8A/MS4A1/SPPL3/ICOSLG/CTLA4/SYK/BTNL9/INPP5D/RELA/HRAS/PTPN2/CD19/CD28/HLA-DQB1/CACNB4/PDE4B/BTN3A2/LILRB4/HLA-DQB1/HLA-DQB1/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/HLA-A/HLA-A/HLA-DQB1/HLA-DPB1/HLA-A/HLA-A/HLA-DPB1/HLA-DPB1/HLA-DPB1/HLA-DQB1/HLA-A/HLA-DQB1/HLA-DQB1/HLA-A/HLA-DPB1/HLA-DPB1/PTPRC/IKBKG/LILRB4/LILRB4/LILRB4/INPP5D 76
GO:0070201 regulation of establishment of protein localization 158/3662 474/15509 6.94641e-07 8.26369e-06 4.96964e-06 BAD/CD38/RHBDF1/IGF1/CASR/CDH1/NNAT/IPO5/SP100/HYAL2/VPS35/CSNK2A2/PRKACA/DERL2/LLGL2/LMAN1/SIRT6/PCM1/GSK3B/XPO1/OXCT1/ACHE/DNM1L/MAVS/P2RX7/HSP90AB1/SH3GLB1/RANGAP1/GZMB/PCK2/FERMT1/NDFIP2/PARD6A/CSK/SFRP1/KCNN4/PDCD5/TGFB1/CD33/GSK3A/MAPK8/PPP3CB/NSD2/ZPR1/HSPA8/CD81/PSMD9/IFNG/PPARD/MAPK14/TMEM30A/APBB3/IL12B/IL1A/PARK7/P3H1/SERP1/TARDBP/ACSL3/SOX4/IL1B/ERGIC3/NR1D1/RAC2/APOE/DKC1/NDFIP1/PER2/PRKAA1/XPO4/CD36/MDFIC/CCT7/GLUL/LCP1/IL6/NMT1/TLR4/ANP32B/CCN3/SORL1/CEP131/SAE1/ENSA/EPHA5/PIK3R1/SNX12/GLUD1/TCF7L2/VEGFC/FOXO1/BAG3/BMP6/DMTN/ITGB2/PCNT/INHBB/BAP1/PRKCD/SLC9B2/ARFIP1/SHH/GPER1/CDK5/GAPVD1/CCT2/CHP2/ADAM9/PKIG/MFF/ITGAM/CDK1/PRKCE/FGG/FGA/BRSK2/LEP/HRAS/CEP135/PDZK1/ATG13/CDK5R1/MIEF2/PTPN11/YOD1/ADIPOQ/F2R/PTP4A3/CIB1/PRKN/UBE2L3/KCNJ11/CLN3/PPIA/SRC/SVIP/UBL5/PIM3/WWP2/UBE2J1/GDI1/HSPA1L/TNF/HSPA1L/TNF/FIS1/TNF/HSPA1L/TNF/TNF/TNF/TNF/TNF/HSPA1L/HSPA1L/CCL5/CCL5/PRKACA 158
GO:2001237 negative regulation of extrinsic apoptotic signaling pathway 45/3662 97/15509 7.10214e-07 8.43277e-06 5.07132e-06 IGF1/SNAI2/HGF/GSK3B/ICAM1/GATA1/EYA1/IL7/SERPINE1/TGFBR1/UNC5B/RPS6KB1/EYA4/IL4/IL1A/PARK7/TNFAIP3/IL1B/PSME3/THBS1/ITGAV/COL2A1/TCF7L2/FAIM/LMNA/PEA15/PF4/TERT/CSF2/NOS3/PRDX2/BCL2L1/FGG/FGA/SCG2/RELA/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 45
GO:0032874 positive regulation of stress-activated MAPK cascade 55/3662 127/15509 7.15014e-07 8.47353e-06 5.09583e-06 WNT16/NOX1/MAPK8IP2/FLT4/EIF2AK2/TRAF1/HIPK2/MAP2K4/SPI1/FCGR2B/TRAF4/OPRK1/GADD45B/BIRC7/RASSF2/AXIN1/PYCARD/NOD1/WNT5A/IL1A/GADD45A/PTK2B/IL1B/BMP2/CCR7/PRMT1/EDA2R/TRAF3/TLR4/CCL21/APP/ARL6IP5/MBIP/TLR3/NOD2/SEMA4C/CCL19/LEP/HRAS/PLCB1/CARD9/WNT7B/HMGB1/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NAIP 55
GO:0051223 regulation of protein transport 152/3662 453/15509 7.27209e-07 8.60161e-06 5.17286e-06 BAD/CD38/RHBDF1/IGF1/CASR/CDH1/NNAT/IPO5/SP100/HYAL2/VPS35/CSNK2A2/PRKACA/DERL2/LLGL2/LMAN1/SIRT6/PCM1/GSK3B/XPO1/OXCT1/ACHE/DNM1L/MAVS/P2RX7/HSP90AB1/SH3GLB1/RANGAP1/GZMB/PCK2/FERMT1/NDFIP2/PARD6A/CSK/SFRP1/KCNN4/PDCD5/TGFB1/CD33/GSK3A/MAPK8/PPP3CB/ZPR1/HSPA8/CD81/PSMD9/IFNG/PPARD/MAPK14/TMEM30A/APBB3/IL12B/IL1A/PARK7/P3H1/SERP1/TARDBP/ACSL3/SOX4/IL1B/ERGIC3/NR1D1/RAC2/APOE/NDFIP1/PER2/PRKAA1/XPO4/CD36/MDFIC/GLUL/LCP1/IL6/NMT1/TLR4/ANP32B/CCN3/SORL1/CEP131/SAE1/ENSA/EPHA5/PIK3R1/SNX12/GLUD1/TCF7L2/VEGFC/FOXO1/BAG3/BMP6/DMTN/ITGB2/PCNT/INHBB/BAP1/PRKCD/SLC9B2/ARFIP1/SHH/GPER1/CDK5/GAPVD1/CHP2/ADAM9/PKIG/MFF/ITGAM/CDK1/PRKCE/FGG/FGA/BRSK2/LEP/HRAS/PDZK1/ATG13/CDK5R1/MIEF2/PTPN11/YOD1/ADIPOQ/F2R/CIB1/PRKN/UBE2L3/KCNJ11/CLN3/PPIA/SRC/SVIP/UBL5/PIM3/WWP2/UBE2J1/GDI1/HSPA1L/TNF/HSPA1L/TNF/FIS1/TNF/HSPA1L/TNF/TNF/TNF/TNF/TNF/HSPA1L/HSPA1L/CCL5/CCL5/PRKACA 152
GO:0002286 T cell activation involved in immune response 47/3662 103/15509 7.37158e-07 8.68613e-06 5.22369e-06 ITGAL/TMEM98/SLC11A1/CD74/FOXP3/FCGR2B/TBX21/IL4R/ICAM1/IL12RB1/SMAD7/LILRB1/JAK3/GATA3/MDK/CD81/IFNG/IL12B/IL4/BCL6/CD86/MYB/CD80/RARA/LCP1/IL6/HLX/IRF4/IL21/IL18/CD1C/IL6R/LGALS9/CCL19/HMGB1/IFNA1/ENTPD7/MTOR/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/LILRB1/LILRB1/LILRB1/HLA-DRA/LILRB1 47
GO:0018107 peptidyl-threonine phosphorylation 47/3662 103/15509 7.37158e-07 8.68613e-06 5.22369e-06 DYRK4/CLK1/HIPK2/ROCK1/SIRT2/CSNK2A2/PRKACA/MARK2/UBE2K/GSK3B/BMP7/SMAD7/AXIN1/PRKD2/TGFB1/GSK3A/TGFBR1/MAPK8/WNT5A/DYRK2/CHI3L1/SPRY2/EGF/MAP3K12/APP/DYRK3/CALM2/PARD3/PRKCA/DMTN/CALM3/TGFBR2/PRKCD/CDK5/DDIT4/CDK1/CDK5R1/CDK10/SPRED2/MTOR/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CSNK2B/PRKDC/PRKACA 47
GO:0035710 CD4-positive, alpha-beta T cell activation 49/3662 109/15509 7.4935e-07 8.80877e-06 5.29744e-06 TMEM98/RUNX3/FOXP3/CBFB/TBX21/IL4R/ARG2/IL12RB1/SMAD7/JAK3/GATA3/CD81/IFNG/IL12B/IL4/BCL6/CD86/CD160/MYB/CD80/TWSG1/NDFIP1/RARA/IL2RA/IL6/HLX/IRF4/IL21/ARMC5/IL2RG/IL18/RUNX1/IL6R/TGFBR2/LGALS9/CCL19/CD28/KLHL25/SOCS1/HMGB1/CD55/ENTPD7/MTOR/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/ITCH 49
GO:0043200 response to amino acid 50/3662 112/15509 7.50408e-07 8.80877e-06 5.29744e-06 BAD/UFL1/CPS1/RRAGD/CYBA/F7/IPO5/RHOA/MMP2/XBP1/RPS6KB1/LAMTOR3/ARG1/DNMT3A/BCL2L2/CDO1/ASS1/SESN2/DNMT1/PDGFRA/TMBIM6/IGF1R/MEAK7/PDGFC/EGFR/NTRK2/ALAD/ZEB1/SESN3/CAPN2/CASP3/CYBB/NSMF/BCL2L1/CEBPB/GRIN1/SLC38A9/NQO1/SOCS1/LAMTOR4/COL4A6/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 50
GO:0097529 myeloid leukocyte migration 85/3662 223/15509 7.75015e-07 9.08042e-06 5.4608e-06 PAFAH1B1/CD9/CD74/SPI1/WDR1/MMP2/DNM1L/PDGFB/CTSG/FLT1/CCL22/CCL17/PIK3CG/SERPINE1/CREB3/CXCL12/C1QBP/CCL2/MDK/CD81/CALCA/IL17A/IL4/IL1A/CCL20/CSF3R/PGF/PTK2B/NUP85/IL1B/CCR7/RAC2/MTUS1/SFTPD/EDNRB/IL6/CCN3/CCL21/THBS1/CYP19A1/TNFRSF11A/SLIT2/PIK3R1/VEGFC/CXCL13/MMP14/KIT/ITGB2/IL6R/CXCR1/PF4/SYK/NOD2/CX3CR1/RHOH/PTK2/CXCL8/SCG2/CCL11/BSG/CCL19/STAT5B/CXCR2/CSF1R/PLCB1/CSF1/PDE4B/HMGB1/PPIA/FUT4/PRTN3/CD47/DPP4/CD177/PECAM1/CCL5/CCL5/CCL4/CCL18/CCL4/MIF/PRTN3/CCL4/CCL18/CCL18 85
GO:0001763 morphogenesis of a branching structure 73/3662 184/15509 7.96473e-07 9.31423e-06 5.60141e-06 HOXA11/SNAI2/HGF/CASR/PRDM1/TIE1/FGFR2/TP63/GLI2/SIRT6/PGR/TMED2/ESR1/ABL1/BMP7/LAMA1/EYA1/SFRP1/TMEM59L/MET/HOXA5/ENG/AREG/MDK/VDR/WNT5A/KDM5B/PKD2/GNA13/BMP2/KDR/LAMA5/KRAS/SPRY2/NKX2-1/IL10/FGF2/EGF/GREB1L/SMAD4/EPHA2/SLIT2/ADAMTS16/NOTCH1/MMP14/WNT4/RBM15/TGFBR2/SHH/BTRC/FRS2/SEMA3E/CCL11/DAG1/GRB2/CTNNBIP1/SETD2/NOG/CSF1/PBX1/SRC/COL13A1/NRARP/TGM2/FKBPL/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 73
GO:0002312 B cell activation involved in immune response 39/3662 80/15509 8.07693e-07 9.42765e-06 5.66962e-06 ST3GAL1/PARP3/FOXP3/SPI1/FCGR2B/TBX21/MLH1/PTPRC/MSH2/ABL1/XBP1/CD40/CD40LG/NBN/IL27RA/TGFB1/EXOSC3/NSD2/POU2AF1/AICDA/IL4/BCL6/PTK2B/SHLD2/NDFIP1/NOTCH2/IL6/IL10/TLR4/IL21/SLC15A4/IRF8/TNFSF13/LIG4/RAG2/CD19/CD28/CR1/PTPRC 39
GO:0034599 cellular response to oxidative stress 96/3662 260/15509 8.41429e-07 9.80296e-06 5.89533e-06 WNT16/MPO/NOX1/BTK/HGF/GLRX2/AIFM2/TMEM161A/SIRT2/SLC25A24/MMP2/PXN/ABL1/GSKIP/APEX1/DHRS2/MMP9/BMP7/ABCC1/GSR/MET/HSPB1/EZH2/MAPK8/PPIF/EPAS1/PARK7/PRDX1/TNFAIP3/ARG1/FOXO3/PKD2/NR4A3/CAT/CHD6/STAU1/BECN1/TRAP1/MGAT3/SESN2/PRKAA1/PDGFRA/CD36/IL6/IL10/TLR4/IL18BP/CYP1B1/MEAK7/SOD1/ARNT/PARP1/RHOB/ARL6IP5/EGFR/NONO/FOXO1/NR4A2/FANCC/TBC1D24/SELENON/FABP1/PRKCD/NOS3/TP53INP1/FXN/PRDX2/CDK1/FOS/MGMT/RELA/ATP2A2/JUN/ERN1/NQO1/PRKN/AKR1C3/PPIA/DAPK1/SRC/MAP3K5/ZNF277/TNF/TNF/ZNF580/CHUK/TNF/TNF/TNF/TNF/TNF/TNF/GAS5/SRXN1/PCGF2/ABCC1 96
GO:0044403 biological process involved in symbiotic interaction 101/3662 277/15509 8.66769e-07 1.00792e-05 6.06148e-06 CD4/LTF/CD74/YTHDC2/THOC3/HYAL2/CDC42/MID2/CHMP5/CCNK/ICAM1/HSP90AB1/SMARCB1/CTSG/CHMP4B/VAPA/KPNA3/SLC1A5/TRIM14/EFNB3/HSPA8/CD81/CD86/FN1/HDAC1/ARG1/VAMP8/TARDBP/TRIM25/CD80/CXCR4/NUP153/NECTIN2/APOE/CHMP1A/TRIM5/TRIM22/SFTPD/ARL8B/ITGAV/SLC7A1/FURIN/EPHA2/EGFR/GSN/NCAM1/HMGA2/ITGB1/EEF1A1/CCR5/INHBB/THOC7/PF4/SAP30/MBL2/PSMC3/ANPEP/TRIM68/SLC3A2/CX3CR1/LGALS9/CXCL8/GYPA/CDK1/TRIM8/BCL2L1/PAIP1/BSG/CFL1/DAG1/CHMP6/JUN/CIITA/F2/EXOC7/CSF1R/PRKN/SLC52A2/IFITM1/CARD9/PLSCR1/HMGB1/PPIA/CD55/IGF2R/SRC/ELANE/DPP4/WWP2/CR1/ZBED1/TRIM26/ITGB3/CCL5/CCL5/CCL4/CCL4/SMARCB1/ELANE/CCL4/ITCH 101
GO:0150076 neuroinflammatory response 35/3662 69/15509 8.92993e-07 1.03647e-05 6.23317e-06 TYROBP/IGF1/TNFRSF1B/GRN/PTPRC/MMP9/CTSC/IFNG/IL4/CLU/LRP1/IL1B/NR1D1/SYT11/DAGLA/IL6/APP/ITGB1/IL18/ITGB2/TLR3/ADCY1/CX3CR1/ITGAM/JUN/TRPV1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC 35
GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 26/3662 45/15509 8.95562e-07 1.03751e-05 6.23942e-06 KDM1A/CD74/CD44/USP28/HIPK2/TP63/TP73/MSH2/BAG6/PYCARD/CDKN1A/DYRK2/BRCA2/ZNF385A/RPL26/SHISA5/DDIT4/TRIAP1/CHEK2/MUC1/BAG6/BAG6/BAG6/BAG6/BAG6/MIF 26
GO:2000045 regulation of G1/S transition of mitotic cell cycle 58/3662 137/15509 8.97252e-07 1.03753e-05 6.23953e-06 KMT2E/FHL1/ARID1B/ACTB/PSME1/CDC6/BCL7C/SMARCB1/APEX1/CASP2/EZH2/SMARCD2/CCL2/CCND1/BCL7A/CCND3/PPP2CA/ID2/ARID1A/PKD2/INHBA/CDKN1A/PSME3/CCNH/APC/RDX/RB1/CUL4A/CYP1A1/CTDSP1/PLK2/EGFR/ADAMTS1/LSM11/APPL1/CUL4B/PRMT2/RPL26/TERT/BRD7/WEE1/RRM1/RFWD3/TRIAP1/RRM2/CTDSP2/CACNB4/PLCB1/CHEK2/CDK10/MUC1/ARID2/KANK2/TFDP1/GIGYF2/PRKDC/SMARCB1/PTEN 58
GO:0032722 positive regulation of chemokine production 36/3662 72/15509 9.80506e-07 1.13169e-05 6.80579e-06 CD74/EIF2AK2/IL4R/MAVS/PYCARD/IL7/IFNG/IL17A/WNT5A/EGR1/IL1B/IL6/TLR4/APP/IL18/IL6R/TLR3/SYK/NOD2/LGALS9/LPL/ADIPOQ/CSF1R/CARD9/HMGB1/TLR7/MBP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MIF 36
GO:0010332 response to gamma radiation 29/3662 53/15509 1.01113e-06 1.16487e-05 7.00533e-06 KDM1A/BAK1/HSPA5/RAD51/CYBA/XRCC5/PTPRC/ZMPSTE24/BAX/GATA3/CRYAB/IL1A/EGR1/CDKN1A/ELK1/PRKAA1/MEN1/BRCA2/PARP1/TLK2/RPL26/BCL2L1/LIG4/HRAS/CHEK2/H2AX/TRIM13/PRKDC/PTPRC 29
GO:0002685 regulation of leukocyte migration 84/3662 221/15509 1.02844e-06 1.18186e-05 7.10752e-06 SELE/CD9/CD74/F7/SPI1/RHOA/DNM1L/ICAM1/ABL1/PYCARD/IL27RA/PTN/SERPINE1/CREB3/CXCL12/C1QBP/CCL2/MDK/CD81/NEDD9/IL4/WNT5A/IL1A/CCL20/ITGA4/PADI2/PGF/PTK2B/CCR7/RAC2/MTUS1/IL6/CCN3/CCL21/THBS1/CYP19A1/APP/ABL2/SLIT2/PIK3R1/MSN/VEGFC/CXCL13/MMP14/IL6R/NOD2/FADD/CX3CR1/RHOH/LGALS9/PTK2/PTAFR/CXCL8/CCL19/SELP/CALR/CXCR2/CSF1R/PLCB1/CSF1/CXCR3/ZP3/HMGB1/FUT4/CD47/ELANE/DPP4/TNF/TNF/ZNF580/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/CCL5/CCL5/CCL4/CCL4/MIF/ELANE/CCL4 84
GO:1905477 positive regulation of protein localization to membrane 46/3662 101/15509 1.0297e-06 1.18186e-05 7.10752e-06 ITGA3/EPHA3/ATP2B4/GZMB/PDCD5/MAPK8/RANGRF/CD81/IFNG/LRP1/ACSL3/EPHB2/LRP4/NMT1/EPHA2/STAC/PIK3R1/EGFR/ITGB1/RER1/ITGB2/GPER1/CDK5/MFF/ITGAM/KIF5B/PRKCE/HRAS/PDZK1/CDK5R1/MIEF2/CIB1/PRKN/STAC3/CLN3/SLC5A3/TNF/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/SQSTM1 46
GO:0001501 skeletal system development 164/3662 499/15509 1.14674e-06 1.31377e-05 7.90078e-06 HOXA11/SCIN/PAFAH1B1/TYROBP/MBTPS2/LTF/IGF1/SNAI2/RUNX3/CD44/BARX2/HEXB/ALX4/PUM2/FGFR2/RHOA/HYAL2/FGFR3/PITX1/NDST1/ATP6AP1/TP63/GLI2/FGFR1/TULP3/HOXA9/PTPRC/HSPB11/ZMPSTE24/MMP2/P2RX7/GLG1/MTHFD1/MMP9/BMP7/RASSF2/SMAD7/PLS3/ACP5/XYLT1/EYA1/SFRP1/SLC39A14/TLE5/LILRB1/TGFB1/HOXA5/SFRP4/TGFBR1/ENG/BMPR1A/HOXB6/RAI1/MAP2K6/NSD2/ZBTB16/MDK/WNT5B/SH2B3/VDR/MAPK14/PEX7/SMAD5/WNT5A/PRRX1/ASH1L/LEPR/P3H1/PRDX1/MTHFD1L/SNX19/SERP1/SOX4/RUNX2/BMP2/THRA/SBDS/KDR/LRRC17/HOXD3/HOXD9/TWSG1/RARA/CHI3L1/LOXL2/NOTCH2/PDGFRA/ADAMTS7/CCN3/TFAP2A/FGF2/FBN2/COL2A1/RB1/HAPLN3/EIF4A3/DYM/EPHA2/CCN1/MEIS1/CSRNP1/PDGFC/ZEB1/SERPINH1/HMGA2/ARID5B/SPEF2/GJA1/BMP6/NODAL/MMP14/KIT/SLC38A10/SKI/ADAMTS4/STC1/RUNX1/ZNF385A/FRZB/TGFBR2/SLC9B2/PITX2/RANBP3L/SHH/TNFRSF11B/RPL13/BMP1/HOXD4/EIF2AK3/RARG/ESRRA/HOXB2/LEP/SMAD2/TYMS/FAM20C/MAF/PTPN11/SETD2/CREB3L2/ANXA2/RFLNB/NOG/NOTUM/PBX1/WNT7B/PAX5/WDR5/COL27A1/SRC/COL13A1/SLC2A10/HOXA4/TGM2/COL11A2/HOXA10/GH1/PTPRC/LOC102724560/LILRB1/LILRB1/LILRB1/PCGF2/LILRB1 164
GO:0002885 positive regulation of hypersensitivity 11/3662 12/15509 1.18309e-06 1.35291e-05 8.13619e-06 BTK/C3/CCR7/ZP3/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 11
GO:0050921 positive regulation of chemotaxis 58/3662 138/15509 1.19491e-06 1.36391e-05 8.20231e-06 CD74/CASR/F7/SPI1/FGFR1/DNM1L/PDGFB/PRKD2/TGFB1/PTN/MET/HSPB1/SERPINE1/CREB3/CXCL12/C1QBP/MDK/NEDD9/SMOC2/IL4/PDGFRB/WNT5A/PGF/PTK2B/CXCR4/CCR7/KDR/RAC2/IL6/CCL21/THBS1/FGF2/SLIT2/TPBG/VEGFC/CXCL13/IL6R/CX3CR1/LGALS9/PTK2/CXCL8/S1PR1/SCG2/IL16/CCL19/CALR/CXCR2/CSF1R/CCR4/CSF1/HMGB1/TMSB4X/ZNF580/CCL5/CCL5/CCL4/CCL4/CCL4 58
GO:0043367 CD4-positive, alpha-beta T cell differentiation 39/3662 81/15509 1.2048e-06 1.37267e-05 8.25502e-06 TMEM98/RUNX3/FOXP3/CBFB/TBX21/IL4R/IL12RB1/SMAD7/JAK3/GATA3/IFNG/IL12B/IL4/BCL6/CD86/MYB/CD80/RARA/IL6/HLX/IRF4/IL21/ARMC5/IL2RG/IL18/RUNX1/IL6R/LGALS9/CCL19/KLHL25/SOCS1/HMGB1/ENTPD7/MTOR/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 39
GO:2000146 negative regulation of cell motility 104/3662 289/15509 1.22075e-06 1.3883e-05 8.34899e-06 NISCH/DCN/CD74/CDH1/ARID4B/ATP2B4/PTPRU/NGFR/TIE1/SP100/RHOA/NAV3/HYAL2/FBLN1/APOH/ANGPT2/APEX1/SMAD7/RBBP7/NDRG4/SFRP1/IL27RA/TGFB1/HAS1/SERPINE1/ENG/GATA3/CXCL12/BMPR1A/CCL2/CORO1C/NEDD9/PPARD/IL4/HDAC1/GADD45A/PADI2/FOXO3/GNA13/RECK/LRP1/SEMG1/RRAS/PIN1/APOE/NKX2-1/CCN3/CCL21/THBS1/CYP19A1/CYP1B1/TET1/FGF2/DUSP10/RHOB/SLIT2/GNA12/IGFBP3/OGT/NOTCH1/GJA1/RNF20/CXCL13/NODAL/STC1/ADIPOR1/RBBP4/WNT4/IL24/SAP30/SHH/TP53INP1/CX3CR1/DAG1/SVBP/CALR/MAPK15/ADIPOQ/ADGRB1/PLCB1/NOG/IFITM1/NF2/MAGI2/ARID2/HMGB1/SPOCK3/SRGAP3/DPP4/CSNK2B/TNF/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/MIF/PTEN 104
GO:0006986 response to unfolded protein 57/3662 135/15509 1.23261e-06 1.39922e-05 8.41467e-06 MBTPS2/UFL1/BAK1/HSPA5/HERPUD1/EIF2AK2/DERL2/TMED2/PPP1R15A/BAX/HSP90AB1/XBP1/BFAR/HSPB1/CREB3/TMEM33/HSPA8/CCND1/PACRG/HSPA9/HSPE1/MFN2/SERP1/TMTC4/HSPA2/CHAC1/ABCB10/DERL1/THBS1/TMBIM6/MANF/PIK3R1/SERPINH1/BAG3/HSPB8/BCL2L11/PPP1R15B/ATF3/CREBRF/VCP/EIF2AK3/DDIT3/PTPN2/ERN1/YOD1/CREB3L2/PRKN/HSPA1L/DAXX/DAXX/HSPA1L/HSPA1L/DAXX/DAXX/DAXX/HSPA1L/HSPA1L 57
GO:0031100 animal organ regeneration 34/3662 67/15509 1.25894e-06 1.42389e-05 8.563e-06 HGF/BAK1/F7/PTPRU/CSNK2A2/ANGPT2/PRPS2/GATA1/HAMP/EZH2/CXCL12/CCND1/NR4A3/PGF/FLT3/LCP1/IL6/IL10/CCNA2/NOTCH1/TGFBR2/NNMT/CDK1/CEBPB/TYMS/IGF2R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 34
GO:0042531 positive regulation of tyrosine phosphorylation of STAT protein 34/3662 67/15509 1.25894e-06 1.42389e-05 8.563e-06 IGF1/FGFR3/PIBF1/OSM/CD40/HPX/IFNG/IL12B/IL4/HES1/FLT3/LIF/EPO/IL6/IL21/IL18/KIT/IL6R/IL24/IL3/CSF2/LEP/CSF1R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GH1/CCL5/CCL5 34
GO:0010921 regulation of phosphatase activity 40/3662 84/15509 1.26431e-06 1.42736e-05 8.58387e-06 ROCK1/PTPRC/GSK3B/PPP1R15A/FKBP1A/HSP90AB1/PPP6R2/URI1/CD33/IFNG/PDGFRB/PTPA/MASTL/CRY2/BMP2/STYXL1/CALM2/BOD1/GNA12/PPP1R15B/CALM3/CHP2/PPP1R2/MAGI2/MTOR/CSNK2B/TNF/PPP1R11/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PTPRC 40
GO:0040013 negative regulation of locomotion 114/3662 324/15509 1.38464e-06 1.56036e-05 9.38374e-06 NISCH/DCN/CD74/CDH1/ARID4B/ATP2B4/PTPRU/NGFR/TIE1/SP100/RHOA/NAV3/HYAL2/ST6GAL1/FBLN1/APOH/ANGPT2/APEX1/SMAD7/RBBP7/NDRG4/SFRP1/IL27RA/TGFB1/HAS1/SERPINE1/ENG/GATA3/CXCL12/BMPR1A/WNT3/CCL2/CORO1C/NEDD9/PPARD/IL4/WNT5A/HDAC1/GADD45A/PADI2/FOXO3/GNA13/RECK/LRP1/SEMG1/RRAS/PIN1/APOE/NKX2-1/CCN3/CCL21/THBS1/CYP19A1/CYP1B1/TET1/FGF2/DUSP10/RHOB/SLIT2/GNA12/IGFBP3/OGT/NOTCH1/GJA1/RNF20/CXCL13/NODAL/STC1/ADIPOR1/RBBP4/WNT4/IL24/SAP30/SHH/TP53INP1/CX3CR1/SEMA4C/SEMA3E/DAG1/PTPN2/SVBP/CALR/MAPK15/ADIPOQ/ADGRB1/PLCB1/NOG/IFITM1/NF2/MAGI2/ARID2/HMGB1/SPOCK3/SRGAP3/ELANE/DPP4/CSNK2B/TNF/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/MIF/ELANE/WNT3/WNT3/PTEN 114
GO:1900180 regulation of protein localization to nucleus 52/3662 120/15509 1.39039e-06 1.56401e-05 9.40565e-06 TMEM98/CDH1/NGFR/IPO5/HYAL2/SIRT6/GSK3B/MAVS/HSP90AB1/FERMT1/TGFB1/ZPR1/IFNG/MAPK14/PARK7/TARDBP/PIN1/LIF/SESN2/DKC1/CD36/MDFIC/CCT7/GLUL/TRIM29/PARP1/PIK3R1/BAG3/LMNA/PRKCD/TERT/SHH/CCT2/CHP2/PKIG/NMD3/CDK1/TRIM8/ORMDL3/EIF2AK3/LEP/LARP7/F2/NPM1/CACNB4/SUMO3/NF2/LILRB4/SRC/LILRB4/LILRB4/LILRB4 52
GO:2000630 positive regulation of miRNA metabolic process 31/3662 59/15509 1.39944e-06 1.57133e-05 9.44969e-06 NGFR/SPI1/PDGFB/TGFB1/GATA3/BMPR1A/MYB/FOXO3/EGR1/BMP2/IL10/SMAD6/FGF2/SMAD4/TERT/FOS/RELA/HRAS/FOSL1/JUN/TEAD1/MRTFA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GAS5 31
GO:0032616 interleukin-13 production 16/3662 22/15509 1.51864e-06 1.6929e-05 1.01808e-05 ARG2/GATA3/IL4/RARA/IRF4/TNFRSF21/IL18/LGALS9/IL1RAP/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 16
GO:0032656 regulation of interleukin-13 production 16/3662 22/15509 1.51864e-06 1.6929e-05 1.01808e-05 ARG2/GATA3/IL4/RARA/IRF4/TNFRSF21/IL18/LGALS9/IL1RAP/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 16
GO:0032695 negative regulation of interleukin-12 production 16/3662 22/15509 1.51864e-06 1.6929e-05 1.01808e-05 PIBF1/TLR8/ACP5/MEFV/LILRB1/JAK3/C1QBP/CCR7/IL10/THBS1/ARRB2/NOD2/LILRB1/LILRB1/LILRB1/LILRB1 16
GO:0051044 positive regulation of membrane protein ectodomain proteolysis 16/3662 22/15509 1.51864e-06 1.6929e-05 1.01808e-05 TNFRSF1B/SH3D19/IFNG/IL1B/APOE/FURIN/ADAM9/RGMA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 16
GO:0033619 membrane protein proteolysis 32/3662 62/15509 1.59096e-06 1.77034e-05 1.06465e-05 MBTPS2/TNFRSF1B/ROCK1/P2RX7/MYH9/TGFB1/SH3D19/IFNG/IL1B/APOE/ADAM19/IL10/MMP7/FURIN/PSEN2/RBMX/SPPL3/ADAM9/DAG1/RGMA/TMPRSS6/PRTN3/TNF/PSENEN/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRTN3 32
GO:0060251 regulation of glial cell proliferation 26/3662 46/15509 1.59773e-06 1.77468e-05 1.06726e-05 UFL1/NTN1/HES1/IL1B/KRAS/IL6/RB1/NOTCH1/VEGFC/SKI/SHH/PLAG1/NF2/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA 26
GO:2000628 regulation of miRNA metabolic process 37/3662 76/15509 1.60169e-06 1.7759e-05 1.068e-05 NGFR/SPI1/PDGFB/TGFB1/GATA3/BMPR1A/PPARD/MYB/FOXO3/EGR1/BMP2/RARA/IL10/SMAD6/FGF2/SMAD4/TERT/FOS/RELA/HRAS/FOSL1/JUN/LILRB4/TEAD1/MRTFA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GAS5/LILRB4/LILRB4/LILRB4 37
GO:0002866 positive regulation of acute inflammatory response to antigenic stimulus 12/3662 14/15509 1.65169e-06 1.8151e-05 1.09157e-05 BTK/PARK7/C3/CCR7/ZP3/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 12
GO:0048291 isotype switching to IgG isotypes 12/3662 14/15509 1.65169e-06 1.8151e-05 1.09157e-05 FOXP3/TBX21/MLH1/PTPRC/MSH2/CD40/IL27RA/IL4/NDFIP1/SLC15A4/CD28/PTPRC 12
GO:0060556 regulation of vitamin D biosynthetic process 12/3662 14/15509 1.65169e-06 1.8151e-05 1.09157e-05 SNAI2/CYP27B1/IFNG/GFI1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 12
GO:0071316 cellular response to nicotine 12/3662 14/15509 1.65169e-06 1.8151e-05 1.09157e-05 BAD/RELA/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/B2M 12
GO:0097527 necroptotic signaling pathway 12/3662 14/15509 1.65169e-06 1.8151e-05 1.09157e-05 FAS/FASLG/TLR3/FADD/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 12
GO:0070316 regulation of G0 to G1 transition 22/3662 36/15509 1.67959e-06 1.84249e-05 1.10804e-05 ARID1B/ACTB/BCL7C/SMARCB1/SMARCD2/BCL7A/ARID1A/SOX15/BRD7/RRM1/RHNO1/FOXO4/ARID2/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/SMARCB1/HLA-G 22
GO:0002468 dendritic cell antigen processing and presentation 15/3662 20/15509 1.72931e-06 1.89035e-05 1.13682e-05 SLC11A1/CD74/FCGR2B/NOD1/CCR7/CD68/CCL21/THBS1/NOD2/CCL19/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 15
GO:0002666 positive regulation of T cell tolerance induction 15/3662 20/15509 1.72931e-06 1.89035e-05 1.13682e-05 FOXP3/TGFBR2/LILRB4/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB4/HLA-G/LILRB4/LILRB4/ITCH 15
GO:0070555 response to interleukin-1 53/3662 124/15509 1.84042e-06 2.00826e-05 1.20773e-05 CD38/UPF1/SELE/YTHDC2/CYBA/HYAL2/MMP2/CD40/CCL22/CCL17/PYCARD/SFRP1/TLE5/CCL2/IL17A/HES1/CCL20/EGR1/IL1B/NR1D1/EPO/AKAP12/CHI3L1/IL6/ADAMTS7/TANK/IL1RN/CCL21/TNFRSF11A/APP/RBMX/PRKCA/INHBB/TNIP2/LGALS9/CXCL8/FGG/CCL11/CEBPB/CCL19/RELA/PLCB1/IRAK1/CD47/SRC/CCL5/CCL5/CCL4/CCL18/CCL4/CCL4/CCL18/CCL18 53
GO:0061043 regulation of vascular wound healing 13/3662 16/15509 1.8659e-06 2.03044e-05 1.22107e-05 XBP1/SERPINE1/SMOC2/TNFAIP3/CXCR4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 13
GO:0032736 positive regulation of interleukin-13 production 14/3662 18/15509 1.8673e-06 2.03044e-05 1.22107e-05 GATA3/IL4/RARA/IRF4/IL18/LGALS9/IL1RAP/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 14
GO:2001235 positive regulation of apoptotic signaling pathway 52/3662 121/15509 1.88334e-06 2.04301e-05 1.22863e-05 BAD/NOX1/FAS/NGFR/HYAL2/TP63/PTPRC/BAX/DNM1L/SRPX/PYCARD/SFRP1/GSDME/CASP2/TGFBR1/SEPTIN4/CTSC/PARK7/TNFSF10/INHBA/EEF1E1/RBCK1/PLAGL2/BECN1/STYXL1/SERINC3/ITM2C/THBS1/PMAIP1/SOD1/BCL2L11/RPL26/PEA15/ATF3/INHBB/PRKCD/GPER1/FADD/DDIT3/PTPN2/PAK2/TNF/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC/PTEN 52
GO:1905475 regulation of protein localization to membrane 66/3662 165/15509 1.88545e-06 2.04301e-05 1.22863e-05 ITGA3/EPHA3/ATP2B4/PICALM/ACTB/GPC4/HECTD1/GZMB/CSK/PDCD5/TGFB1/MAPK8/RANGRF/CD81/IFNG/TMEM59/VAMP8/LRP1/ACSL3/PPFIA1/EPHB2/LRP4/NMT1/EPHA2/STAC/PIK3R1/EGFR/GSN/ITGB1/MMP14/APPL1/RER1/LDLRAP1/DMTN/ITGB2/AP2M1/GPER1/CDK5/MFF/ITGAM/CDH2/KIF5B/PRKCE/BCL2L1/DAG1/HRAS/PDZK1/CDK5R1/MIEF2/CIB1/PRKN/STAC3/CLN3/FZD9/SLC5A3/GDI1/TNF/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/SQSTM1 66
GO:0009895 negative regulation of catabolic process 103/3662 288/15509 1.89902e-06 2.05412e-05 1.23531e-05 SLC4A1/HFE/SLC11A1/HGF/CLEC16A/PHF23/ATP2B4/HIPK2/CTSA/ELAVL1/KDM4A/ROCK1/SIRT2/VPS35/CSNK2A2/SIRT6/FUS/HNRNPC/BAG6/HSP90AB1/CIRBP/CHMP4B/USP14/N4BP1/TSC2/SNRNP70/SGTA/GSK3A/PIK3CG/MET/TRDMT1/LARP4B/EIF4G2/MAPK14/PDCL3/PARK7/LEPR/SLIRP/NRDE2/TARDBP/USP9X/IL1B/BECN1/PIN1/ZFP36/MGAT3/CBFA2T3/DKC1/PRKAA1/TBC1D14/PTPN22/SERPINE2/IL10/SORL1/FURIN/TOB1/SMAD4/EGFR/TLK2/OGT/SNX12/EIF3H/ALAD/USP25/TAB3/MAPKAPK2/RYBP/SHH/GOLGA2/DDIT4/ALK/PAIP1/RELA/ANGEL2/LEP/TMEM39A/WDR6/NQO1/ADGRB1/ANXA2/RBM10/USP7/SECISBP2/SVIP/MTOR/RNF5/BAG6/TNF/TNF/MAGEA3/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/HP/TAF15/F8A1 103
GO:0050920 regulation of chemotaxis 81/3662 214/15509 1.92958e-06 2.08354e-05 1.25301e-05 CD74/CASR/F7/SPI1/ST6GAL1/FGFR1/DNM1L/ANGPT2/PDGFB/USP14/PRKD2/TGFB1/PTN/MET/HSPB1/SERPINE1/CREB3/CXCL12/WNT3/C1QBP/CCL2/MDK/NEDD9/SMOC2/IL4/PDGFRB/WNT5A/PADI2/PGF/PTK2B/CXCR4/CCR7/KDR/RAC2/MTUS1/PDGFRA/IL6/CCN3/CCL21/TUBB2B/THBS1/CYP19A1/FGF2/SLIT2/TPBG/NOTCH1/VEGFC/POU4F2/CXCL13/IL6R/NOD2/CX3CR1/SEMA4C/LGALS9/PTK2/CXCL8/SEMA3E/S1PR1/SCG2/IL16/CCL19/PTPN2/CALR/CXCR2/CSF1R/CCR4/CSF1/HMGB1/ELANE/DPP4/TMSB4X/ZNF580/CCL5/CCL5/CCL4/CCL4/MIF/ELANE/WNT3/WNT3/CCL4 81
GO:0001776 leukocyte homeostasis 42/3662 91/15509 1.95061e-06 2.0953e-05 1.26008e-05 BTK/CD74/FAS/BAK1/TNFRSF17/FOXP3/BAX/P2RX7/ABL1/MTHFD1/JAK3/PPP3CB/SH2B3/MPL/TNFAIP3/GPAM/FLT3/PKN1/IL2RA/IL6/SLC15A4/PMAIP1/BCL2L11/MERTK/TSC22D3/XKR8/SPTA1/BAP1/CASP3/RAG1/LMO1/PRDX2/FADD/LGALS9/STAT5B/CXCR2/F2R/CSF1/PDE4B/HMGB1/TNFRSF13B/MIF 42
GO:1990868 response to chemokine 42/3662 91/15509 1.95061e-06 2.0953e-05 1.26008e-05 RHOA/CCL22/CCL17/CXCL12/CCL2/SH2B3/CCL20/PADI2/MPL/GPR75/PTK2B/CXCR4/RNF113A/CCR7/CCL21/SLIT2/CXCL13/CXCR5/CCR5/RBM15/CXCR1/PF4/WBP1L/CX3CR1/CXCL8/CCL11/CCL19/CCR9/CXCR2/CCR4/SLIT3/CIB1/CXCR3/ACKR1/CCL5/CCL5/CCL4/CCL18/CCL4/CCL4/CCL18/CCL18 42
GO:1990869 cellular response to chemokine 42/3662 91/15509 1.95061e-06 2.0953e-05 1.26008e-05 RHOA/CCL22/CCL17/CXCL12/CCL2/SH2B3/CCL20/PADI2/MPL/GPR75/PTK2B/CXCR4/RNF113A/CCR7/CCL21/SLIT2/CXCL13/CXCR5/CCR5/RBM15/CXCR1/PF4/WBP1L/CX3CR1/CXCL8/CCL11/CCL19/CCR9/CXCR2/CCR4/SLIT3/CIB1/CXCR3/ACKR1/CCL5/CCL5/CCL4/CCL18/CCL4/CCL4/CCL18/CCL18 42
GO:0050435 amyloid-beta metabolic process 30/3662 57/15509 1.9706e-06 2.11311e-05 1.27079e-05 IGF1/ROCK1/PICALM/GSK3A/IFNG/CLU/BECN1/PIN1/MGAT3/APOE/RTN3/SORL1/RTN1/PSEN2/REN/NTRK2/SLC2A13/CASP3/EFNA1/RELA/MME/TNF/PSENEN/TNF/TNF/TNF/TNF/TNF/TNF/TNF 30
GO:0006413 translational initiation 49/3662 112/15509 1.98333e-06 2.11578e-05 1.27239e-05 DHX33/EIF2AK2/EIF4B/DDX1/BZW1/TMED2/PPP1R15A/EIF3J/HSPB1/EIF3B/EIF4H/EIF3A/RPS6KB1/EIF4G2/EIF1B/EIF2B2/PAIP2/EIF2S2/EIF4E2/BZW2/NCBP1/POLR2D/EIF3H/EIF4EBP2/EIF3M/CDC123/EIF4A2/PPP1R15B/EIF4A1/EIF2AK3/PAIP1/EIF1/NPM1/RPS17/KLHL25/EIF3C/YTHDF3/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/CCL5/CCL5 49
GO:0018210 peptidyl-threonine modification 49/3662 112/15509 1.98333e-06 2.11578e-05 1.27239e-05 DYRK4/CLK1/HIPK2/ROCK1/SIRT2/CSNK2A2/PRKACA/MARK2/UBE2K/GSK3B/BMP7/SMAD7/AXIN1/PRKD2/TGFB1/GSK3A/TGFBR1/MAPK8/WNT5A/GALNT3/DYRK2/CHI3L1/SPRY2/EGF/MAP3K12/APP/DYRK3/CALM2/PARD3/PRKCA/DMTN/CALM3/TGFBR2/PRKCD/CDK5/DDIT4/CDK1/CDK5R1/GALNT11/CDK10/SPRED2/MTOR/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CSNK2B/PRKDC/PRKACA 49
GO:0032355 response to estradiol 49/3662 112/15509 1.98333e-06 2.11578e-05 1.27239e-05 BAD/CD38/F7/MBD3/APOB/MMP2/ESR1/BMP7/SFRP1/GPI/TGFB1/EZH2/AREG/CRYAB/CCND1/PDGFRB/IGFBP2/DNMT3A/CAT/ALDH1A2/BCL2L2/ARPC1B/ASS1/RARA/IL10/STXBP1/CYP19A1/CYP1B1/IGF1R/CCNA2/EGFR/POU4F2/POU4F1/BCL2L11/CASP3/GPER1/GPX4/KAT5/ESRRA/STAT5B/LEP/CALR/SSTR2/OXTR/NQO1/ZNF703/GH1/TXNIP/GPI 49
GO:2000181 negative regulation of blood vessel morphogenesis 47/3662 106/15509 2.01848e-06 2.14958e-05 1.29272e-05 E2F2/DCN/SARS1/ATP2B4/EPN1/TIE1/ROCK1/APOH/ANGPT2/AGO1/HOXA5/SERPINE1/STAT1/GADD45A/CD160/FASLG/TEK/SPRY2/THBS1/EPHA2/PLK2/HHEX/ADAMTS1/WNT4/PF4/SEMA3E/ADGRB1/FOXO4/HGS/THBS2/TNF/HLA-G/TNF/HLA-G/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/YJEFN3/HLA-G 47
GO:0010638 positive regulation of organelle organization 149/3662 450/15509 2.20025e-06 2.33914e-05 1.40672e-05 BAD/CDC27/SCIN/DCN/IGF1/SPAST/ZDHHC6/BAK1/GRN/IFT88/RHOA/NAV3/SIRT2/VPS35/CDC42/WDR1/LMAN1/ARHGEF10L/SPAG5/SIRT6/ACTN2/XRCC5/GSK3B/ATRX/BAX/DNM1L/MAPKAPK5/P2RX7/ANAPC5/PXN/ABL1/SH3GLB1/PDGFB/KCTD17/GZMB/MMP9/HCK/PYCARD/NBN/SFRP1/ARHGEF10/PDCD5/GSK3A/MET/TGFBR1/MAPK8/PPIF/CSF3/RAD50/IL5/MACROH2A1/PDGFRB/SMC4/WNT5A/SNX4/INO80D/IL1A/SDC1/PARK7/ELAPOR1/SLF2/TEK/PTK2B/TNFSF10/CNOT1/IL1B/DSTN/ID1/CCR7/BECN1/KDR/CDC42EP1/POT1/DNMT1/DKC1/WASF3/KATNBL1/PSRC1/PPHLN1/HRK/HNRNPA1/CCT7/LCP1/NMT1/CCL21/NUMA1/NUSAP1/ABI2/EGF/NABP2/RB1/SLAIN1/BBS4/PMAIP1/MSN/GSN/CDC42EP2/BCL2L11/ARHGAP35/ALOX15/TAL1/WNT4/CDC42EP3/FYCO1/RICTOR/CSF2/GPER1/CDK5/CCT2/ATMIN/MFF/ADRB2/PDCD6IP/PRKCE/CCL11/KAT5/LIG4/HRAS/CEP135/CDK5R1/MIEF2/GRB2/CD28/AURKB/MAPK15/PLCB1/ANXA2/PRKN/DRG1/NF2/CD47/SRC/MTOR/TNF/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/PDXP/PGAM5/BRK1/RTEL1/PIP4K2B/SEPTIN9/TINF2 149
GO:0030225 macrophage differentiation 25/3662 44/15509 2.22246e-06 2.35467e-05 1.41605e-05 CD4/SPI1/CDC42/CEBPE/MMP9/TGFB1/IFNG/ID2/INHBA/LIF/TSPAN2/RB1/APP/PARP1/PRKCA/PF4/CSF2/FADD/PTPN2/ADIPOQ/CSF1R/CSF1/SOCS1/L3MBTL3/CEBPA 25
GO:0090199 regulation of release of cytochrome c from mitochondria 25/3662 44/15509 2.22246e-06 2.35467e-05 1.41605e-05 BAD/IGF1/HGF/BAK1/BAX/DNM1L/MMP9/PYCARD/PDCD5/PPIF/CLU/TNFSF10/BCL2L2/HRK/ARRB2/PMAIP1/BCL2L11/LMNA/GPER1/FXN/MFF/PRELID1/TRIAP1/BCL2L1/PRKN 25
GO:0031056 regulation of histone modification 62/3662 153/15509 2.29463e-06 2.42698e-05 1.45954e-05 NFYA/KDM1A/KMT2E/PAF1/AASS/BAZ1B/SNAI2/FOXP3/HPF1/KDM4A/NFYC/SPI1/ZMPSTE24/ATRX/DNMT3B/SMARCB1/PRKD2/GATA3/MAPK8/ZNF451/MACROH2A1/BCL6/SF3B1/KDM3A/PARK7/DR1/MYB/PHF19/DEK/LIF/PRDM12/DNMT1/MYBBP1A/WBP2/TET1/SKIC8/SMAD4/NCAPG2/OGT/NSD3/KAT14/MBIP/SMARCA5/RNF20/SKI/CTBP1/LMNA/GFI1/PYGO2/NSD1/BRD7/NNMT/SETD5/TADA3/HCFC1/TAF7/MUC1/NOC2L/PAX5/WDR5/SMARCB1/TADA2A 62
GO:0045622 regulation of T-helper cell differentiation 23/3662 39/15509 2.34548e-06 2.47233e-05 1.48682e-05 FOXP3/TBX21/IL4R/IL12RB1/SMAD7/JAK3/GATA3/IL12B/IL4/BCL6/CD86/MYB/CD80/RARA/HLX/IRF4/IL18/CCL19/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 23
GO:0050901 leukocyte tethering or rolling 23/3662 39/15509 2.34548e-06 2.47233e-05 1.48682e-05 SELE/ROCK1/ADD2/CXCL12/ITGA4/CCL21/ITGB1/VCAM1/CX3CR1/PTAFR/SELP/LEP/FUT4/ELANE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ELANE 23
GO:0001836 release of cytochrome c from mitochondria 28/3662 52/15509 2.37845e-06 2.49858e-05 1.5026e-05 BAD/GGCT/IGF1/HGF/BAK1/BAX/DNM1L/MMP9/PYCARD/PDCD5/PPIF/CLU/TNFSF10/BCL2L2/HRK/ARRB2/PMAIP1/BCL2L11/LMNA/GPER1/FXN/MFF/PRELID1/TRIAP1/BCL2L1/PRKN/FZD9/FIS1 28
GO:0032768 regulation of monooxygenase activity 28/3662 52/15509 2.37845e-06 2.49858e-05 1.5026e-05 ATP2B4/CDH3/FCER2/NOD1/CYP27B1/VDR/IFNG/IL1A/PARK7/PTK2B/IL1B/APOE/EGFR/DDAH1/CALM3/GFI1/TERT/LEP/ZDHHC21/CNR2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 28
GO:0032984 protein-containing complex disassembly 81/3662 215/15509 2.3879e-06 2.50426e-05 1.50602e-05 UPF1/SCIN/SPAST/CLEC16A/PHF23/VMP1/NAV3/TBC1D25/SPTB/WDR1/NSF/ADD2/ACTN2/GSK3B/ZMPSTE24/CHMP5/ADD1/TPX2/SUPT16H/SNAP29/SMARCB1/TFIP11/CHMP4B/MTPN/SMARCD2/HSPA8/CAPZA1/STMN1/ARID1A/VAMP8/MTRF1/DSTN/BECN1/ATG14/CHMP1A/APC/SNX14/MICAL1/HMGA1/RDX/IGF1R/SH3GL1/KIF2C/DYRK3/SNAPIN/GSN/SSRP1/PLEKHH2/SCAF4/DMTN/SPTBN4/SPTA1/FYCO1/VCP/DDIT4/ADRB2/KIF5B/CFL1/SPTBN2/ATP2A2/CHMP6/TMEM39A/FLII/H2AC25/CIB1/CLN3/ARID2/SPTAN1/IQANK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PDXP/TWF2/LIX1L/SMARCB1 81
GO:0032693 negative regulation of interleukin-10 production 18/3662 27/15509 2.46301e-06 2.57868e-05 1.55077e-05 BTK/TYROBP/FOXP3/FCGR2B/LILRB1/JAK3/IL12B/TNFRSF21/PRG2/LILRB4/PDCD1LG2/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 18
GO:0061515 myeloid cell development 38/3662 80/15509 2.49835e-06 2.59126e-05 1.55834e-05 SLC4A1/PAFAH1B1/TYROBP/LTF/ALAS1/ATP6AP1/GATA1/ERCC2/LILRB1/SLC11A2/SH2B3/RHAG/BCL6/MYB/PTBP3/EPO/TSPAN2/NOTCH2/ABCB10/APP/MEIS1/KIT/ALAS2/DMTN/ZNF385A/BAP1/SLC9B2/EPB42/CEBPB/FAM20C/PTPN11/ANXA2/SRC/L3MBTL3/LILRB1/LILRB1/LILRB1/LILRB1 38
GO:0002294 CD4-positive, alpha-beta T cell differentiation involved in immune response 32/3662 63/15509 2.5043e-06 2.59126e-05 1.55834e-05 TMEM98/FOXP3/TBX21/IL4R/IL12RB1/SMAD7/JAK3/GATA3/IFNG/IL12B/IL4/BCL6/CD86/MYB/CD80/RARA/IL6/HLX/IRF4/IL21/IL18/IL6R/LGALS9/CCL19/HMGB1/ENTPD7/MTOR/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 32
GO:0032613 interleukin-10 production 32/3662 63/15509 2.5043e-06 2.59126e-05 1.55834e-05 BTK/TYROBP/HGF/FOXP3/FCGR2B/PIBF1/CD40LG/PYCARD/LILRB1/JAK3/IL12B/IL4/IL6/TLR4/IRF4/TNFRSF21/SYK/NOD2/LGALS9/CD28/PRG2/LILRB4/HMGB1/CD47/PDCD1LG2/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 32
GO:0032623 interleukin-2 production 32/3662 63/15509 2.5043e-06 2.59126e-05 1.55834e-05 CD4/FOXP3/NAV3/TBX21/PTPRC/ABL1/PRKD2/GATA3/PDE4D/CD86/IL1A/TNFAIP3/CD80/IL1B/ZFP36/SFTPD/IRF4/RUNX1/NOD2/KAT5/STAT5B/GLMN/CD28/PDE4B/LILRB4/CARD9/PNP/CR1/PTPRC/LILRB4/LILRB4/LILRB4 32
GO:0032653 regulation of interleukin-10 production 32/3662 63/15509 2.5043e-06 2.59126e-05 1.55834e-05 BTK/TYROBP/HGF/FOXP3/FCGR2B/PIBF1/CD40LG/PYCARD/LILRB1/JAK3/IL12B/IL4/IL6/TLR4/IRF4/TNFRSF21/SYK/NOD2/LGALS9/CD28/PRG2/LILRB4/HMGB1/CD47/PDCD1LG2/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 32
GO:0032663 regulation of interleukin-2 production 32/3662 63/15509 2.5043e-06 2.59126e-05 1.55834e-05 CD4/FOXP3/NAV3/TBX21/PTPRC/ABL1/PRKD2/GATA3/PDE4D/CD86/IL1A/TNFAIP3/CD80/IL1B/ZFP36/SFTPD/IRF4/RUNX1/NOD2/KAT5/STAT5B/GLMN/CD28/PDE4B/LILRB4/CARD9/PNP/CR1/PTPRC/LILRB4/LILRB4/LILRB4 32
GO:0032731 positive regulation of interleukin-1 beta production 32/3662 63/15509 2.5043e-06 2.59126e-05 1.55834e-05 TYROBP/P2RX7/TLR8/MEFV/PYCARD/NOD1/HSPB1/IFNG/IL17A/WNT5A/EGR1/CD36/IL6/TLR4/APP/GBP5/NOD2/LGALS9/CCL19/LPL/TNF/TNF/TNF/TNF/TNF/TNF/ORM1/TNF/TNF/NAIP/NAIP/NAIP 32
GO:0071214 cellular response to abiotic stimulus 108/3662 307/15509 2.62245e-06 2.70449e-05 1.62643e-05 BAD/KDM1A/MAP3K14/NOX1/CRY1/SNAI2/FAS/BAK1/HSPA5/USP28/RAD51/CYBA/TMEM161A/MYLK/MAP2K4/HYAL2/XRCC5/ZMPSTE24/BAX/MMP2/MMP9/CD40/ACTR5/TLR8/NFAT5/N4BP1/PIEZO1/PYCARD/SFRP1/EEF1D/HAMP/MTPN/CASP2/ENG/GATA3/MAPK8/CRYAB/ASIC1/MAPK14/GADD45A/SLC2A1/PKD2/EGR1/TNFRSF10B/TNFRSF8/CRY2/KCNJ2/CDKN1A/IL1B/SLC25A23/ELK1/EPO/DDB2/NMT1/TANK/TLR4/XPA/FGF2/BRCA2/CUL4A/IGF1R/PARP1/RHOB/PIK3R1/TLK2/BAG3/NMT2/BMP6/XPC/CUL4B/AQP5/RPL26/SCNN1D/PRKCD/CASP3/TLR3/TP53INP1/NSMF/FADD/LETM1/PTAFR/MAP3K2/MGMT/TRIAP1/BCL2L1/RHNO1/DAG1/LIG4/HRAS/GRB2/PLEC/AURKB/CALR/NPM1/H2AC25/CHEK2/ZFP36L1/H2AX/CLN3/NOC2L/MME/MMP1/TLR7/TRPV1/MTOR/SIPA1/ITGB3/PTEN 108
GO:0104004 cellular response to environmental stimulus 108/3662 307/15509 2.62245e-06 2.70449e-05 1.62643e-05 BAD/KDM1A/MAP3K14/NOX1/CRY1/SNAI2/FAS/BAK1/HSPA5/USP28/RAD51/CYBA/TMEM161A/MYLK/MAP2K4/HYAL2/XRCC5/ZMPSTE24/BAX/MMP2/MMP9/CD40/ACTR5/TLR8/NFAT5/N4BP1/PIEZO1/PYCARD/SFRP1/EEF1D/HAMP/MTPN/CASP2/ENG/GATA3/MAPK8/CRYAB/ASIC1/MAPK14/GADD45A/SLC2A1/PKD2/EGR1/TNFRSF10B/TNFRSF8/CRY2/KCNJ2/CDKN1A/IL1B/SLC25A23/ELK1/EPO/DDB2/NMT1/TANK/TLR4/XPA/FGF2/BRCA2/CUL4A/IGF1R/PARP1/RHOB/PIK3R1/TLK2/BAG3/NMT2/BMP6/XPC/CUL4B/AQP5/RPL26/SCNN1D/PRKCD/CASP3/TLR3/TP53INP1/NSMF/FADD/LETM1/PTAFR/MAP3K2/MGMT/TRIAP1/BCL2L1/RHNO1/DAG1/LIG4/HRAS/GRB2/PLEC/AURKB/CALR/NPM1/H2AC25/CHEK2/ZFP36L1/H2AX/CLN3/NOC2L/MME/MMP1/TLR7/TRPV1/MTOR/SIPA1/ITGB3/PTEN 108
GO:0042100 B cell proliferation 41/3662 89/15509 2.73138e-06 2.81214e-05 1.69117e-05 CD38/BTK/TYROBP/CD22/CD74/FCGR2B/PTPRC/BAX/ABL1/CD40/NFATC2/CD40LG/IL7/CD79A/AHR/CD81/IL4/IL5/BCL6/PKN1/CDKN1A/CD70/EPHB2/IL10/TLR4/IL21/TNFRSF21/MS4A1/TNFRSF13C/CTLA4/PRKCD/CASP3/INPP5D/RAG2/CD19/IFNA1/TNFRSF13B/PTPRC/MIF/INPP5D/PTEN 41
GO:0032612 interleukin-1 production 48/3662 110/15509 2.74831e-06 2.82021e-05 1.69602e-05 TYROBP/IGF1/ARG2/P2RX7/TLR8/ACP5/MEFV/PYCARD/CD33/NOD1/HSPB1/IFNG/IL17A/WNT5A/TNFAIP3/EGR1/CCR7/CD36/IL6/IL10/TLR4/ARRB2/APP/GBP5/NOD2/CX3CR1/LGALS9/IL16/CCL19/LPL/F2R/LILRB4/HMGB1/TNF/TNF/TNF/TNF/TNF/TNF/ORM1/TNF/TNF/NAIP/LILRB4/NAIP/LILRB4/LILRB4/NAIP 48
GO:0032652 regulation of interleukin-1 production 48/3662 110/15509 2.74831e-06 2.82021e-05 1.69602e-05 TYROBP/IGF1/ARG2/P2RX7/TLR8/ACP5/MEFV/PYCARD/CD33/NOD1/HSPB1/IFNG/IL17A/WNT5A/TNFAIP3/EGR1/CCR7/CD36/IL6/IL10/TLR4/ARRB2/APP/GBP5/NOD2/CX3CR1/LGALS9/IL16/CCL19/LPL/F2R/LILRB4/HMGB1/TNF/TNF/TNF/TNF/TNF/TNF/ORM1/TNF/TNF/NAIP/LILRB4/NAIP/LILRB4/LILRB4/NAIP 48
GO:0042119 neutrophil activation 26/3662 47/15509 2.77414e-06 2.82931e-05 1.7015e-05 KMT2E/TYROBP/GRN/SPI1/FCGR2B/STXBP2/CTSG/IL18/ITGB2/PRKCD/SYK/PTAFR/CXCL8/ITGAM/CXCR2/TNF/CD177/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CCL5/CCL5 26
GO:0008625 extrinsic apoptotic signaling pathway via death domain receptors 42/3662 92/15509 2.77539e-06 2.82931e-05 1.7015e-05 BAD/HGF/SPI1/SP100/GSK3B/BAX/ICAM1/SFRP1/SERPINE1/PARK7/FASLG/TNFAIP3/TNFRSF10B/NGF/THBS1/PMAIP1/PIK3R1/BAG3/FAIM/PEA15/ATF3/ZDHHC3/NOS3/FADD/BCL2L1/FGG/FGA/DAPK1/TNF/DAXX/DAXX/TNF/TNF/DAXX/TNF/TNF/TNF/DAXX/TNF/DAXX/TNF/PTEN 42
GO:0002673 regulation of acute inflammatory response 29/3662 55/15509 2.77544e-06 2.82931e-05 1.7015e-05 BTK/FCGR2B/OSM/PIK3CG/IL4/PARK7/ASH1L/IL1B/C3/CCR7/EDNRB/IL6/TNFRSF11A/ZP3/TNF/HLA-E/TNF/HLA-E/TNF/HLA-E/TNF/TNF/TNF/HLA-E/TNF/HLA-E/TNF/HLA-E/HLA-E 29
GO:0043525 positive regulation of neuron apoptotic process 29/3662 55/15509 2.77544e-06 2.82931e-05 1.7015e-05 TYROBP/GRN/MAP2K4/RHOA/BAX/ABL1/MYBL2/GSK3A/CASP2/FASLG/FOXO3/SRPK2/TFAP2A/POU4F1/BCL2L11/CASP3/CDK5/ITGAM/DDIT3/CDK5R1/NQO1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 29
GO:1901343 negative regulation of vasculature development 47/3662 107/15509 2.78192e-06 2.83125e-05 1.70266e-05 E2F2/DCN/SARS1/ATP2B4/EPN1/TIE1/ROCK1/APOH/ANGPT2/AGO1/HOXA5/SERPINE1/STAT1/GADD45A/CD160/FASLG/TEK/SPRY2/THBS1/EPHA2/PLK2/HHEX/ADAMTS1/WNT4/PF4/SEMA3E/ADGRB1/FOXO4/HGS/THBS2/TNF/HLA-G/TNF/HLA-G/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/YJEFN3/HLA-G 47
GO:0019827 stem cell population maintenance 63/3662 157/15509 2.82136e-06 2.86669e-05 1.72397e-05 PAF1/MED17/ARID4B/BICRA/ELAVL1/SPI1/SMC1A/TP63/ACTB/PCM1/KDM2B/BCL7C/MED15/SMARCB1/BMP7/RBBP7/SETD6/SFRP1/PTN/BMPR1A/SMC3/DDX6/BCL7A/HES1/KDM3A/BCL9/PRRX1/HDAC1/ARID1A/FOXO3/PHF19/SOX4/CNOT1/LIF/MED6/LOXL2/TAF5L/TET1/CUL4A/OGT/NOTCH1/HMGA2/FOXO1/ZFP36L2/KLF10/NODAL/KIT/SKI/FANCC/PADI4/TAF6L/RBBP4/SAP30/MED30/RBPJ/CDH2/TRIM8/LIG4/NOG/BCL9L/ZNF358/SMARCB1/PADI4 63
GO:0032753 positive regulation of interleukin-4 production 20/3662 32/15509 3.04292e-06 3.08171e-05 1.85328e-05 FOXP3/CD40LG/GATA3/CD86/RARA/IRF4/SYK/LGALS9/CEBPB/CD28/PRG2/ZP3/IL1RAP/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 20
GO:0045672 positive regulation of osteoclast differentiation 20/3662 32/15509 3.04292e-06 3.08171e-05 1.85328e-05 TYROBP/IFNG/NEDD9/IL17A/IL12B/NOTCH2/POU4F2/POU4F1/KLF10/SLC9B2/FOS/CSF1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 20
GO:0030336 negative regulation of cell migration 99/3662 277/15509 3.08526e-06 3.10978e-05 1.87017e-05 NISCH/DCN/CD74/CDH1/ARID4B/ATP2B4/PTPRU/NGFR/TIE1/SP100/RHOA/NAV3/HYAL2/APOH/ANGPT2/APEX1/SMAD7/RBBP7/NDRG4/SFRP1/IL27RA/TGFB1/HAS1/SERPINE1/ENG/CXCL12/BMPR1A/CCL2/CORO1C/NEDD9/PPARD/IL4/HDAC1/GADD45A/PADI2/FOXO3/GNA13/RECK/LRP1/RRAS/APOE/NKX2-1/CCN3/CCL21/THBS1/CYP19A1/CYP1B1/TET1/FGF2/DUSP10/RHOB/SLIT2/GNA12/IGFBP3/OGT/NOTCH1/GJA1/RNF20/CXCL13/NODAL/STC1/ADIPOR1/RBBP4/WNT4/IL24/SAP30/SHH/TP53INP1/CX3CR1/DAG1/SVBP/CALR/MAPK15/ADIPOQ/ADGRB1/PLCB1/NOG/IFITM1/NF2/MAGI2/ARID2/HMGB1/SRGAP3/DPP4/CSNK2B/TNF/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/MIF/PTEN 99
GO:1902003 regulation of amyloid-beta formation 24/3662 42/15509 3.08838e-06 3.10978e-05 1.87017e-05 IGF1/ROCK1/PICALM/GSK3A/IFNG/CLU/PIN1/APOE/RTN3/SORL1/RTN1/NTRK2/SLC2A13/CASP3/EFNA1/RELA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 24
GO:1904037 positive regulation of epithelial cell apoptotic process 24/3662 42/15509 3.08838e-06 3.10978e-05 1.87017e-05 BAD/BAX/CD40/CD40LG/SFRP4/CCL2/ITGA4/CD160/FASLG/FOXO3/IL6/THBS1/ARRB2/GSN/GPER1/AKR1C3/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 24
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process 134/3662 399/15509 3.09072e-06 3.10978e-05 1.87017e-05 CDC27/PSMB1/HFE/PSMC4/RNF14/UFL1/HSPA5/HERPUD1/RNF4/ATXN3/SIRT2/SEL1L/FBXW11/DERL2/TBX21/MKRN2/TRAF4/SIRT6/UBE2A/UBE2K/PCNP/GSK3B/XPO1/PSMC5/NSFL1C/ANAPC5/HECTD1/BAG6/HSP90AB1/PSMD8/KCTD17/PSMC6/PSMA3/PSMA6/USP14/SMAD7/N4BP1/AXIN1/BFAR/SGTA/GSK3A/DVL1/FBXW4/PSMD3/CCDC47/UBE4A/USP5/MAN1A1/SKP1/PARK7/CDC20/FBXL5/RAD23B/AREL1/CLU/TRIM25/USP9X/KLHDC3/RBCK1/FBXL12/CBFA2T3/ADRM1/UBE2G1/FBXO44/HSPBP1/RNF122/APC/AKIRIN2/ECPAS/DERL1/FAM8A1/RNF121/CUL4A/ARRB2/CSNK1D/DTL/SPOPL/FEM1C/GNA12/TLK2/OGT/ERLIN2/EIF3H/DNAJB12/RNF144A/CLGN/UCHL1/FBXL18/UBXN11/CUL4B/ZFAND2B/PSMB4/PSMC2/SPSB3/WDR26/RYBP/PSMD6/RCHY1/SHH/TMUB1/VCP/NEMF/PSMC3/BTRC/RNF187/SPSB1/KAT5/PSMD1/GLMN/KCTD13/PSMD2/DDIT3/CALR/YOD1/PRKN/PRAME/USP7/PCBP2/SVIP/WWP2/UBE2J1/DCAF12/RNF5/BAG6/FBXO48/TRIM13/BAG6/BAG6/BAG6/BAG6/CEBPA/FBXO17/PSMB3/ITCH 134
GO:0006479 protein methylation 70/3662 180/15509 3.10206e-06 3.1111e-05 1.87096e-05 NFYA/KDM1A/KMT2E/PAF1/AASS/ARID4B/PRDM1/KDM4A/NFYC/ATRX/MECOM/DNMT3B/SMARCB1/SNRPD3/SETD6/DOT1L/FBL/EZH2/GATA3/EZH1/NSD2/HCFC2/MACROH2A1/KDM3A/ASH1L/MYB/PHF19/DNMT3A/EEF1AKMT3/H1-3/PRMT1/ASH2L/PRDM12/DNMT1/PRMT7/MEN1/TET1/SKIC8/SMAD4/CARM1/BOD1/OGT/NSD3/SMARCA5/RNF20/BTG2/PRMT2/LMNA/GFI1/PYGO2/NSD1/NNMT/SETD5/H1-4/COPRS/HCFC1/TRMT112/SUZ12/SETD2/SETD3/KMT5A/TET3/H1-2/PAX5/WDR5/WDR5B/NCOA6/PCMTD2/SMARCB1/PAGR1 70
GO:0008213 protein alkylation 70/3662 180/15509 3.10206e-06 3.1111e-05 1.87096e-05 NFYA/KDM1A/KMT2E/PAF1/AASS/ARID4B/PRDM1/KDM4A/NFYC/ATRX/MECOM/DNMT3B/SMARCB1/SNRPD3/SETD6/DOT1L/FBL/EZH2/GATA3/EZH1/NSD2/HCFC2/MACROH2A1/KDM3A/ASH1L/MYB/PHF19/DNMT3A/EEF1AKMT3/H1-3/PRMT1/ASH2L/PRDM12/DNMT1/PRMT7/MEN1/TET1/SKIC8/SMAD4/CARM1/BOD1/OGT/NSD3/SMARCA5/RNF20/BTG2/PRMT2/LMNA/GFI1/PYGO2/NSD1/NNMT/SETD5/H1-4/COPRS/HCFC1/TRMT112/SUZ12/SETD2/SETD3/KMT5A/TET3/H1-2/PAX5/WDR5/WDR5B/NCOA6/PCMTD2/SMARCB1/PAGR1 70
GO:0060445 branching involved in salivary gland morphogenesis 17/3662 25/15509 3.12555e-06 3.12454e-05 1.87905e-05 SNAI2/HGF/FGFR2/BMP7/LAMA1/LAMA5/SHH/DAG1/TGM2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 17
GO:0071800 podosome assembly 17/3662 25/15509 3.12555e-06 3.12454e-05 1.87905e-05 RHOA/HCK/IL5/LCP1/DBNL/MSN/GSN/CSF2/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 17
GO:0050769 positive regulation of neurogenesis 83/3662 223/15509 3.15565e-06 3.14955e-05 1.89409e-05 KDM1A/PAFAH1B1/UFL1/TNFRSF1B/NTN1/PLXNA2/TP73/XRCC5/LRP2/ADNP/TGFB1/PTN/CXCL12/WNT3/MDK/IFNG/DBN1/HES1/FN1/ID2/HDAC1/CXCR4/EGR2/OBSL1/IL1B/NKX2-2/BMP2/LIF/EPHB2/KRAS/NGF/SERPINE2/IL6/DBNL/ACTR2/FGF2/CRABP2/SLIT2/NTRK2/NOTCH1/ITGB1/VEGFC/POU4F2/KIT/FAIM/TBC1D24/DISC1/SHH/GPER1/CX3CR1/RGS14/LPAR3/MAP6/DAG1/LIG4/BDNF/CDH4/PLAG1/SS18L1/MME/MTOR/GPRASP3/TGM2/GDI1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/TWF2/SHANK3/CUX1/NEFL/WNT3/WNT3 83
GO:0032633 interleukin-4 production 22/3662 37/15509 3.21911e-06 3.20257e-05 1.92597e-05 FOXP3/CD40LG/GATA3/CD86/NDFIP1/RARA/IRF4/SYK/LGALS9/CEBPB/DDIT3/CD28/PRG2/ZP3/IL1RAP/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 22
GO:0032673 regulation of interleukin-4 production 22/3662 37/15509 3.21911e-06 3.20257e-05 1.92597e-05 FOXP3/CD40LG/GATA3/CD86/NDFIP1/RARA/IRF4/SYK/LGALS9/CEBPB/DDIT3/CD28/PRG2/ZP3/IL1RAP/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 22
GO:0032386 regulation of intracellular transport 107/3662 305/15509 3.36555e-06 3.34289e-05 2.01036e-05 CDH1/ATP9A/IPO5/SP100/HYAL2/VPS35/CSNK2A2/PRKACA/DERL2/LMAN1/SPAG5/SIRT6/ACTN2/PCM1/GSK3B/XPO1/MAVS/HSP90AB1/SH3GLB1/RANGAP1/MLC1/GZMB/FERMT1/NDRG4/PDCD5/TGFB1/GSK3A/MAPK8/CRYAB/ZPR1/CD81/IFNG/MAPK14/BVES/TMEM30A/PARK7/TNNT2/NRDE2/TARDBP/NUP153/IL1B/ERGIC3/RAC2/PRKAA1/REEP2/XPO4/CD36/MDFIC/LCP1/NMT1/ANP32B/NUMA1/SORL1/RDX/CEP131/SAE1/SNAPIN/PIK3R1/MSN/SNX12/TCF7L2/BAG3/LDLRAP1/DMTN/ITGB2/PCNT/BAP1/PRKCD/ARFIP1/SHH/CDK5/CHP2/PKIG/MFF/ITGAM/CDK1/ARV1/BRSK2/LEP/HRAS/PDZK1/ATG13/CDK5R1/MIEF2/PTPN11/YOD1/MAPK15/ADIPOQ/SETD2/ANXA2/CIB1/PRKN/UBE2L3/USP7/PGAP1/SRC/SVIP/UBL5/UBE2J1/GDI1/HSPA1L/HSPA1L/FIS1/HSPA1L/HSPA1L/HSPA1L/PRKACA 107
GO:0031331 positive regulation of cellular catabolic process 127/3662 375/15509 3.45247e-06 3.42374e-05 2.05898e-05 BAD/UPF1/DCN/RNF14/UFL1/IGF1/TNFRSF1B/HERPUD1/ROCK1/SIRT2/MKRN2/MLH1/SIRT6/MID2/GSK3B/TUT7/ATG16L1/BAX/P2RX7/HECTD1/SH3GLB1/SMAD7/AXIN1/NPRL3/TSC2/MEFV/SGTA/GSK3A/NOD1/TRIM14/EXOSC3/DVL1/SH3D19/IFNG/USP5/IL4/SNX4/TMEM59/PARK7/ELAPOR1/CDC20/FOXO3/CLU/PTK2B/TARDBP/CNOT1/IL1B/BECN1/ZFP36/KDR/CBFA2T3/APOE/SESN2/TRIM5/TRIM22/PRKAA1/GRSF1/HSPBP1/IL6/TTC5/EGF/FURIN/TOB1/CSNK1D/TRIM65/APP/ARNT/POLR2D/CNOT9/PLK2/C9orf72/SESN3/FOXO1/RNF144A/BAG3/HSPB8/ZFP36L2/BCL2L11/CNOT11/ZC3H18/BTG2/DISC1/FABP1/RCHY1/FYCO1/PRKCD/TP53INP1/VCP/NOD2/TRIM68/GPD1/ADAM9/ADRB2/PTK2/TRIM8/ORMDL3/PAIP1/DCP2/KAT5/PDE12/ATG13/MAGEF1/RGMA/PRKN/ZFP36L1/YTHDF3/HMGB1/DAPK1/SVIP/MTOR/GIGYF2/DXO/TNF/TRIM13/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GAS5/CEBPA/IKBKG/PIP4K2B/PTEN/ITCH 127
GO:0010596 negative regulation of endothelial cell migration 31/3662 61/15509 3.53372e-06 3.49314e-05 2.10071e-05 DCN/ATP2B4/SP100/RHOA/APOH/ANGPT2/TGFB1/GADD45A/APOE/THBS1/FGF2/SLIT2/NOTCH1/CXCL13/STC1/SVBP/ADGRB1/HMGB1/CSNK2B/TNF/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B 31
GO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress 31/3662 61/15509 3.53372e-06 3.49314e-05 2.10071e-05 BAK1/HERPUD1/PPP1R15A/BAX/BAG6/XBP1/CREB3/PARK7/TNFRSF10B/CHAC1/SERINC3/TMBIM6/PMAIP1/ITPR1/BCL2L11/BCL2L1/EIF2AK3/CEBPB/BRSK2/DDIT3/PTPN2/ERN1/GRINA/PRKN/MAP3K5/BAG6/MAGEA3/BAG6/BAG6/BAG6/BAG6 31
GO:0030323 respiratory tube development 71/3662 184/15509 3.67025e-06 3.62233e-05 2.1784e-05 ITGA3/FLT4/FGFR2/CDC42/GLI2/TRAF4/TULP3/TP73/HSPB11/PGR/ADAMTS2/RBBP9/BAG6/LAMA1/HOXA5/AIMP2/BMPR1A/PDGFRB/NPHP3/WNT5A/HES1/EPAS1/ARG1/THRA/ELK1/KDR/LIF/ALDH1A2/FOXJ1/LAMA5/AP3B1/CHI3L1/SFTPD/KRAS/PDGFRA/SPRY2/NKX2-1/FGF2/CYP1A2/NOTCH1/THRB/NODAL/MMP14/SELENON/TGFBR2/SHH/NOS3/ABCA3/RBPJ/NKIRAS2/ZFPM2/DAG1/SMAD2/NOG/WNT7B/MME/NKIRAS1/BAG6/TNF/TNF/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/CEBPA 71
GO:0045732 positive regulation of protein catabolic process 74/3662 194/15509 3.79337e-06 3.73789e-05 2.2479e-05 OSBPL7/MYLIP/PSMC4/RNF14/TNFRSF1B/HERPUD1/ATXN3/SIRT2/VPS35/NSF/MKRN2/SIRT6/LRP2/GSK3B/PSMC5/HECTD1/BAG6/MARCHF2/PSMC6/SMAD7/AXIN1/SGTA/HAMP/GSK3A/DVL1/SH3D19/CD81/IFNG/USP5/WNT5A/CDC20/TNFAIP3/FBXL5/CLU/LRP1/IL1B/CBFA2T3/APOE/NDFIP1/HSPBP1/APC/SORL1/RDX/FURIN/CSNK1D/DTL/PLK2/MSN/FOXO1/RNF144A/CUL4B/PSMC2/RCHY1/VCP/PSMC3/ADAM9/RGMA/PRKN/ATG7/BAG6/TNF/TNF/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/CEBPA/ITCH 74
GO:0045766 positive regulation of angiogenesis 62/3662 155/15509 3.81496e-06 3.74725e-05 2.25353e-05 HGF/GRN/HIPK2/TIE1/PKM/SIRT6/ANGPT2/ABL1/XBP1/CD40/FLT1/TJP1/PRKD2/HSPB1/SERPINE1/ENG/MDK/SMOC2/WNT5A/IL1A/PDCL3/WARS2/PGF/TEK/PTK2B/CXCR4/IL1B/C3/RRAS/KDR/CHI3L1/BTG1/IL10/THBS1/CYP1B1/FGF2/ITGAX/RHOB/HMGA2/ITGB1/VEGFC/DDAH1/PRKCA/NODAL/RUNX1/EMC10/JAK1/TGFBR2/AGGF1/TLR3/TERT/NOS3/CYBB/STIM1/CX3CR1/CXCL8/CCL11/CXCR2/PDCD6/ITGB3/AKT3/TJP1 62
GO:1904018 positive regulation of vasculature development 62/3662 155/15509 3.81496e-06 3.74725e-05 2.25353e-05 HGF/GRN/HIPK2/TIE1/PKM/SIRT6/ANGPT2/ABL1/XBP1/CD40/FLT1/TJP1/PRKD2/HSPB1/SERPINE1/ENG/MDK/SMOC2/WNT5A/IL1A/PDCL3/WARS2/PGF/TEK/PTK2B/CXCR4/IL1B/C3/RRAS/KDR/CHI3L1/BTG1/IL10/THBS1/CYP1B1/FGF2/ITGAX/RHOB/HMGA2/ITGB1/VEGFC/DDAH1/PRKCA/NODAL/RUNX1/EMC10/JAK1/TGFBR2/AGGF1/TLR3/TERT/NOS3/CYBB/STIM1/CX3CR1/CXCL8/CCL11/CXCR2/PDCD6/ITGB3/AKT3/TJP1 62
GO:0016525 negative regulation of angiogenesis 46/3662 105/15509 3.85923e-06 3.76844e-05 2.26627e-05 E2F2/DCN/SARS1/ATP2B4/EPN1/TIE1/ROCK1/APOH/ANGPT2/AGO1/HOXA5/SERPINE1/STAT1/GADD45A/CD160/FASLG/TEK/SPRY2/THBS1/EPHA2/PLK2/HHEX/ADAMTS1/PF4/SEMA3E/ADGRB1/FOXO4/HGS/THBS2/TNF/HLA-G/TNF/HLA-G/TNF/TNF/TNF/TNF/TNF/HLA-G/TNF/HLA-G/HLA-G/HLA-G/HLA-G/YJEFN3/HLA-G 46
GO:0002287 alpha-beta T cell activation involved in immune response 32/3662 64/15509 3.87984e-06 3.76844e-05 2.26627e-05 TMEM98/FOXP3/TBX21/IL4R/IL12RB1/SMAD7/JAK3/GATA3/IFNG/IL12B/IL4/BCL6/CD86/MYB/CD80/RARA/IL6/HLX/IRF4/IL21/IL18/IL6R/LGALS9/CCL19/HMGB1/ENTPD7/MTOR/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 32
GO:0002293 alpha-beta T cell differentiation involved in immune response 32/3662 64/15509 3.87984e-06 3.76844e-05 2.26627e-05 TMEM98/FOXP3/TBX21/IL4R/IL12RB1/SMAD7/JAK3/GATA3/IFNG/IL12B/IL4/BCL6/CD86/MYB/CD80/RARA/IL6/HLX/IRF4/IL21/IL18/IL6R/LGALS9/CCL19/HMGB1/ENTPD7/MTOR/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 32
GO:0002886 regulation of myeloid leukocyte mediated immunity 32/3662 64/15509 3.87984e-06 3.76844e-05 2.26627e-05 BTK/TYROBP/GAB2/C12orf4/SPI1/FCGR2B/STXBP2/IL4R/DDX1/MAVS/GATA1/IL4/SNX4/ARG1/VAMP8/C3/RAC2/STXBP1/ITGB2/SYK/CX3CR1/LGALS9/PTAFR/ITGAM/HLA-E/CD177/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 32
GO:0046850 regulation of bone remodeling 25/3662 45/15509 3.88108e-06 3.76844e-05 2.26627e-05 CD38/P2RX7/CSK/SFRP1/HAMP/MDK/CALCA/LEPR/TNFAIP3/SPP1/IAPP/IL6/DEF8/TNFRSF11A/PRKCA/TNFRSF11B/SYK/INPP5D/S1PR1/GPR137/LEP/CSF1R/SRC/ITGB3/INPP5D 25
GO:0050850 positive regulation of calcium-mediated signaling 25/3662 45/15509 3.88108e-06 3.76844e-05 2.26627e-05 CD4/PTBP1/IGF1/ERBB3/P2RX5/PPP3CB/ZAP70/SPPL3/SYK/CHP2/HINT1/CIB1/P2RX2/TNF/TNF/STIMATE/TNF/TNF/TNF/TNF/TNF/TNF/CCL4/CCL4/CCL4 25
GO:2001239 regulation of extrinsic apoptotic signaling pathway in absence of ligand 25/3662 45/15509 3.88108e-06 3.76844e-05 2.26627e-05 SNAI2/FGFR1/SRPX/GATA1/EYA1/IL7/UNC5B/EYA4/IL1A/INHBA/IL1B/COL2A1/PF4/TERT/CSF2/PRDX2/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 25
GO:0010001 glial cell differentiation 80/3662 214/15509 3.88658e-06 3.76844e-05 2.26627e-05 TMEM98/CNTN1/TNFRSF1B/GRN/ERBB3/KDM4A/RHOA/SIRT2/WDR1/TP73/ABL1/CSK/ARHGEF10/ERCC2/TGFB1/PTN/CNTNAP1/MDK/IFNG/HES1/ID2/HDAC1/EIF2B2/CLU/CXCR4/EGR2/LRP1/SOX4/MYRF/IL1B/NKX2-2/BMP2/NR1D1/LIF/WASF3/KRAS/TSPAN2/SERPINE2/IL6/NKX2-1/TLR4/FGF2/SOD1/APP/DUSP10/TNFRSF21/NTRK2/NOTCH1/PARD3/SKI/CUL4B/B4GALT5/MXRA8/SLC25A46/SHH/CDK5/CDK1/CDH2/LAMB2/DAG1/CNP/KCNJ10/PLEC/SUZ12/PTPN11/F2/NOG/CNTN2/POU3F2/ROR1/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTEN 80
GO:0002645 positive regulation of tolerance induction 16/3662 23/15509 3.89126e-06 3.76844e-05 2.26627e-05 FOXP3/FOXJ1/TGFBR2/LILRB4/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/LILRB4/HLA-G/LILRB4/LILRB4/ITCH 16
GO:0007059 chromosome segregation 113/3662 327/15509 4.09422e-06 3.95881e-05 2.38076e-05 CDC27/BAZ1B/CENPQ/ARID1B/PUM2/MSH4/SIRT2/CSNK2A2/CDC42/SMC1A/NDE1/ACTB/MLH1/SPAG5/NDC80/PIBF1/ATRX/SEH1L/CHMP5/ZW10/ANAPC5/BIRC5/NUDC/KIF4A/CDC6/BAG6/BCL7C/SMARCB1/CCNB1IP1/CHMP4B/RIOK3/UBE2I/RAB11A/ERCC2/CCNE1/SMC3/RECQL5/SMARCD2/BCL7A/FBXO5/MACROH2A1/SMC4/KAT2B/TTL/CDC20/NSL1/ARID1A/SLF2/TEX14/NAA50/PDS5A/CENPK/USP9X/BECN1/MAU2/CEP85/CHMP1A/TOP2A/CCNB1/ARL8B/PSRC1/CDCA8/APC/NUMA1/NUSAP1/KIF23/KNL1/ACTR2/CENPE/RB1/KIF2C/ARL8A/CIAO1/CENPC/BOD1/TLK2/NCAPG2/MKI67/SPC25/SMARCA5/SKA1/EME1/GEM/SKA3/BRD7/CENPN/RGS14/BUB1/CENPX/KAT5/ZWILCH/CCNE2/BANF1/RMI2/CHMP6/RMI1/AURKB/RCC2/MAPK15/KMT5A/PLSCR1/ARID2/BAG6/SYCE1L/BAG6/BAG6/BAG6/BAG6/KIFC1/SMARCB1/NDE1/TOP3A/SPICE1 113
GO:0009746 response to hexose 69/3662 178/15509 4.14877e-06 4.00531e-05 2.40872e-05 BAD/CASR/CYBA/RHOA/PDK3/PRKACA/OPRK1/OXCT1/NOX4/ICAM1/ANGPT2/SMARCB1/XBP1/PCK2/SLC39A14/PPP3CB/RPS6KB1/PPARD/SLC29A1/FOXO3/EIF2B2/GPAM/EGR1/PTK2B/SOX4/NKX2-2/NR1D1/SESN2/PRKAA1/MEN1/GLUL/THBS1/KHK/IGF1R/SMAD4/COL6A2/PKLR/EPHA5/TCF7L2/TGFBR2/SLC9B2/CASP3/GPER1/CCDC186/PRKCE/NPTX1/KAT5/BRSK2/SMAD2/LPL/ERN1/RMI1/ADIPOQ/MAFA/SLC8A1/PIM3/SELENOT/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PKLR/TXNIP/SMARCB1/PRKACA 69
GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation 21/3662 35/15509 4.4056e-06 4.24664e-05 2.55386e-05 FOXP3/IL4R/IL12RB1/IFNG/IL12B/CD86/MYB/CD80/RARA/HLX/IL2RG/IL18/LGALS9/CCL19/KLHL25/SOCS1/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 21
GO:2001020 regulation of response to DNA damage stimulus 99/3662 279/15509 4.41481e-06 4.24891e-05 2.55522e-05 KDM1A/CRY1/BAZ1B/SNAI2/CD74/CD44/PARP3/ARID1B/RAD51/FAM168A/TMEM161A/ACTB/SIRT6/ZMPSTE24/ATXN7L3/FUS/ABL1/BCL7C/SMARCB1/TFIP11/RBBP8/EYA1/YJU2/ZNHIT1/CXCL12/RECQL5/SMARCD2/DDX5/NSD2/BCL7A/FOXM1/FBXO5/EYA4/KAT2B/NEK4/INO80D/ARID1A/SLF2/CLU/SHLD2/MORF4L2/SOX4/DEK/EEF1E1/YEATS4/AUNIP/POT1/TAF5L/EPC2/IER3/ACTR2/BRCA2/CUL4A/PMAIP1/DYRK3/PARP1/EGFR/RADX/PPP4C/HMGA2/SMARCA5/CCDC117/MRNIP/ZNF385A/RPL26/TAF6L/PRKCD/BRD7/RNF169/NUDT16L1/RFWD3/MGMT/TRIAP1/TADA3/BCL2L1/KAT5/RMI2/MAGEF1/TAF7/NPM1/SETD2/PTTG1IP/CHEK2/KMT5A/MUC1/H2AX/ARID2/HMGB1/TRRAP/SPRED2/IER3/IER3/IER3/IER3/IER3/PRKDC/RTEL1/SMARCB1/MIF 99
GO:0034250 positive regulation of cellular amide metabolic process 59/3662 146/15509 4.42777e-06 4.25478e-05 2.55875e-05 ELAVL1/PKM/RHOA/PICALM/PPP1R15A/GCN1/CIRBP/PCIF1/GSK3A/LARP4B/RPS6KB1/C1QBP/IFNG/PASK/SERP1/CLU/PTK2B/SOX4/NIBAN1/IL6/THBS1/CYP1B1/LARP1B/TARBP2/TOB1/EIF4A3/CCN1/POLR2D/SLC2A13/CDC123/GUF1/RMND1/USP16/RPL26/PRKCD/CASP3/RPUSD4/NOD2/EFNA1/PTAFR/PAIP1/RELA/CD28/NPM1/EIF3C/YTHDF3/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/PRKDC/CCL5/CCL5 59
GO:0002604 regulation of dendritic cell antigen processing and presentation 10/3662 11/15509 4.6128e-06 4.39849e-05 2.64517e-05 SLC11A1/CD74/FCGR2B/NOD1/CCR7/CD68/CCL21/THBS1/NOD2/CCL19 10
GO:0002941 synoviocyte proliferation 10/3662 11/15509 4.6128e-06 4.39849e-05 2.64517e-05 BTK/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 10
GO:0016098 monoterpenoid metabolic process 10/3662 11/15509 4.6128e-06 4.39849e-05 2.64517e-05 CYP2D6/CYP2E1/CYP1A2/CYP3A4/CYP2C19/CYP2D6/CYP2D6/CYP2D6/CYP2D6/CYP2D6 10
GO:1901645 regulation of synoviocyte proliferation 10/3662 11/15509 4.6128e-06 4.39849e-05 2.64517e-05 BTK/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 10
GO:1901647 positive regulation of synoviocyte proliferation 10/3662 11/15509 4.6128e-06 4.39849e-05 2.64517e-05 BTK/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 10
GO:1902991 regulation of amyloid precursor protein catabolic process 26/3662 48/15509 4.69638e-06 4.4713e-05 2.68896e-05 IGF1/ROCK1/PICALM/FKBP1A/GSK3A/IFNG/CLU/PIN1/APOE/FLOT2/RTN3/SORL1/RTN1/NTRK2/SLC2A13/CASP3/EFNA1/RELA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 26
GO:0034728 nucleosome organization 57/3662 140/15509 4.85995e-06 4.61993e-05 2.77835e-05 ATRX/SUPT16H/SMARCB1/CHRAC1/ZNHIT1/SMARCD2/MACROH2A1/ARID1A/H1-3/H2BC11/YEATS4/HP1BP3/ANP32B/HMGA1/ANP32E/SSRP1/SMARCA5/H2BC5/CHAF1B/PADI4/H3-3A/CHAF1A/H1-4/KAT5/NPM1/H2AC25/SETD2/H2BC21/H1-2/H2AX/H1-0/ARID2/H2BC26/BRD2/DAXX/DAXX/DNAJC9/BRD2/DAXX/DAXX/BRD2/DAXX/H2BC15/BRD2/BRD2/H4C15/H4C14/H4C12/H2BC6/H3C6/SMARCB1/H4C5/H4C4/H2BC7/H3C10/PADI4/H3C2 57
GO:0010633 negative regulation of epithelial cell migration 36/3662 76/15509 4.93924e-06 4.68095e-05 2.81504e-05 DCN/ATP2B4/SP100/RHOA/APOH/ANGPT2/TGFB1/CORO1C/IL4/GADD45A/APOE/THBS1/FGF2/DUSP10/SLIT2/NOTCH1/CXCL13/STC1/ADIPOR1/SVBP/ADGRB1/HMGB1/CSNK2B/TNF/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PTEN 36
GO:0042982 amyloid precursor protein metabolic process 36/3662 76/15509 4.93924e-06 4.68095e-05 2.81504e-05 IGF1/SOAT1/ROCK1/PICALM/ACHE/FKBP1A/GSK3A/IFNG/CLU/NECAB3/PIN1/APOE/FLOT2/RTN3/ADAM19/ITM2C/SORL1/RTN1/PSEN2/NTRK2/SLC2A13/LDLRAP1/CASP3/EFNA1/RELA/CLN3/TNF/PSENEN/TNF/TNF/TNF/TNF/TNF/TNF/TNF/AATF 36
GO:0060541 respiratory system development 76/3662 202/15509 5.10963e-06 4.83503e-05 2.9077e-05 ITGA3/FLT4/FGFR2/CDC42/GLI2/TULP3/TP73/HSPB11/PGR/ADAMTS2/RBBP9/BAG6/LAMA1/RPGRIP1L/HOXA5/AIMP2/BMPR1A/PDGFRB/NPHP3/WNT5A/HES1/EPAS1/ARG1/THRA/ELK1/KDR/LIF/ALDH1A2/FOXJ1/LAMA5/ASS1/RARA/AP3B1/CHI3L1/SFTPD/KRAS/PDGFRA/SPRY2/NKX2-1/FGF2/CYP1A2/NOTCH1/THRB/SPEF2/NODAL/MMP14/SKI/SELENON/TGFBR2/SHH/NOS3/ABCA3/RBPJ/NKIRAS2/ZFPM2/RARG/DAG1/SMAD2/NOG/WNT7B/MME/NKIRAS1/BAG6/TNF/TNF/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/CEBPA 76
GO:0010038 response to metal ion 114/3662 332/15509 5.2213e-06 4.93317e-05 2.96672e-05 BAD/HFE/PPP5C/CPS1/CASR/CDH1/HSPA5/RASGRP2/SLC25A24/ADD1/P2RX7/MMP9/GPI/HAMP/GSK3A/TFR2/MAPK8/PPIF/CCND1/SLC11A2/CUTA/PPP2CA/WNT5A/IL1A/SLC30A3/IGFBP2/SDC1/PARK7/TNNT2/ARG1/PKD2/DNMT3A/PTK2B/CAT/SLC25A23/FOSB/BECN1/ASS1/PRKAA1/SYT11/LOXL2/TFAP2A/THBS1/KHK/CARF/CYP1A1/CYP1A2/IMPA2/SOD1/APP/KCNH1/PKLR/PARP1/SYT2/CALM2/EGFR/ALAD/BMP6/KIT/DMTN/CALM3/ADAMTS13/ALOX15/VCAM1/INHBB/CASP3/TERT/SHH/ADCY1/TNFRSF11B/FXN/TRPV6/CYBB/AQP3/CHP2/STIM1/ADAM9/AHCYL1/ARL13B/CDK1/FOS/CD14/NPTX1/FGG/FGA/GPHN/EIF2AK3/BSG/LIG4/JUN/KCNJ10/CALR/NQO1/PRKN/PLSCR1/AKR1C3/CACNA1H/MBP/GDI1/DAXX/DAXX/CHUK/CPNE1/DAXX/DAXX/DAXX/CEBPA/PDCD6/PKLR/TXNIP/B2M/TRPV6/ADAMTS13/GPI 114
GO:0002444 myeloid leukocyte mediated immunity 46/3662 106/15509 5.27047e-06 4.97205e-05 2.9901e-05 KMT2E/BTK/TYROBP/GAB2/C12orf4/SPI1/WDR1/FCGR2B/STXBP2/IL4R/DDX1/LAT2/MAVS/CTSG/GATA1/PIK3CG/IL4/SNX4/ARG1/VAMP8/NR4A3/C3/RAC2/IL6/STXBP1/CPLX2/KIT/ITGB2/SYK/CX3CR1/LGALS9/PTAFR/ITGAM/SERPINB9/F2/CARD9/ELANE/HLA-E/CD177/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/ELANE 46
GO:0033209 tumor necrosis factor-mediated signaling pathway 45/3662 103/15509 5.35161e-06 5.04092e-05 3.03152e-05 BIRC3/FAS/TNFRSF1B/TNFRSF17/TRAF1/UBE2K/NFKBIA/BIRC7/PYCARD/KRT18/STAT1/TNFAIP3/FOXO3/PTK2B/H2BC11/CD70/EDA2R/TRAF3/PIAS3/TNFRSF11A/COMMD7/TNFRSF13C/SYK/NKIRAS2/LIMS1/RELA/PTPN2/ADIPOQ/TRAIP/PRKN/NKIRAS1/TNF/TMSB4X/TNF/CHUK/CPNE1/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NAIP 45
GO:0071824 protein-DNA complex subunit organization 89/3662 246/15509 5.4478e-06 5.12374e-05 3.08133e-05 MED24/MED17/RAD51/MED29/RNF4/SIRT6/ATRX/ESR1/SUPT16H/MED15/SMARCB1/PSMC6/TAF1C/CHRAC1/MED25/ZNHIT1/SMARCD2/MACROH2A1/DR1/ARID1A/HELLS/CENPK/H1-3/H2BC11/THRA/YEATS4/HP1BP3/MED6/ANP32B/HMGA1/TAF8/CENPE/RB1/ANP32E/CENPC/BDP1/SSRP1/SMARCA5/H2BC5/CHAF1B/PADI4/TAF6L/H3-3A/MED30/GTF2A1/CENPN/CHAF1A/H1-4/CENPX/KAT5/MED16/TAF7/NPM1/H2AC25/SETD2/H2BC21/BRF1/H1-2/CENPP/H2AX/H1-0/ARID2/HMGB1/H2BC26/TAF13/BRD2/DAXX/DAXX/DNAJC9/BRD2/DAXX/DAXX/BRD2/DAXX/H2BC15/BRD2/BRD2/H4C15/H4C14/H4C12/H2BC6/H3C6/SMARCB1/H4C5/H4C4/H2BC7/H3C10/PADI4/H3C2 89
GO:0043550 regulation of lipid kinase activity 31/3662 62/15509 5.47647e-06 5.14291e-05 3.09285e-05 FGFR3/CDC42/EPHA8/PIK3IP1/PDGFB/EEF1A2/FLT1/TGFB1/CCKBR/CD81/PDGFRB/CISH/TEK/PTK2B/FLT3/CCR7/ATG14/PDGFRA/CCL21/FGF2/RB1/PIK3R1/KIT/NOD2/PTK2/CCL19/CD19/F2/SOCS1/SRC/PIP4K2B 31
GO:0051090 regulation of DNA-binding transcription factor activity 132/3662 396/15509 5.62727e-06 5.27652e-05 3.17321e-05 KDM1A/DHX33/BTK/MBTPS2/LTF/UFL1/FOXP3/EIF2AK2/TRAF1/HIPK2/SPI1/SP100/TCF3/MID2/ERC1/MAVS/ESR1/SMARCB1/PSMA6/NFKBIA/CD40/BMP7/HCK/SMAD7/CD40LG/SETD6/PYCARD/PRKD2/MTPN/TAX1BP1/NOD1/EZH2/SFRP4/TRIM14/MAPK8/CSF3/IL5/WNT5A/HES1/ID2/PARK7/TNFAIP3/PKD2/SFRP5/CLU/TRIM25/CAT/IL1B/RBCK1/BMP2/ID1/FOXJ1/EDA2R/TRAF3/TRIM5/TRIM22/FLOT2/BEX1/MEN1/BHLHE40/CD36/IL6/IL10/TLR4/CYP1B1/CARF/RB1/ARRB2/TNFRSF11A/APP/HES6/EPHA5/TCF7L2/PPRC1/COMMD7/ARID5B/IL18/POU4F2/POU4F1/NODAL/KIT/PRMT2/GFI1/HEYL/TLR3/SHH/ADCY1/SYK/BTRC/NOD2/TRIM68/PRDX2/CX3CR1/LGALS9/ALK/TRIM8/RELA/FZD4/DDIT3/FOSL1/CTNNBIP1/NPM1/TRAIP/IRAK1/CIB1/SIGIRR/ROR1/RNF220/USP7/CARD9/IL1RAP/PPIA/TFDP1/WWP2/NTRK1/TNF/TRIM13/TMSB4X/TNF/CHUK/TNF/TNF/TNF/TNF/TNF/TNF/TRIM26/IKBKG/SMARCB1/LRP6/PTEN/ITCH 132
GO:1901990 regulation of mitotic cell cycle phase transition 100/3662 284/15509 5.80056e-06 5.43079e-05 3.26598e-05 CDC27/KMT2E/FHL1/ARID1B/SIRT2/ACTB/NDC80/ZW10/ANAPC5/BIRC5/PSME1/CDC6/CDC7/BCL7C/SMARCB1/APEX1/CDC25B/RBBP8/RAB11A/NBN/ERCC2/CASP2/EZH2/SMARCD2/CCL2/CCND1/BCL7A/FBXO5/CCND3/CCNG1/RAD50/PPP2CA/ID2/CDC20/ARID1A/PKD2/TEX14/INHBA/CDKN1A/HSPA2/PSME3/CCNB1/CCNH/CDCA8/APC/RDX/CENPE/NABP2/RB1/CUL4A/CYP1A1/APP/DTL/INTS3/CTDSP1/PLK2/EGFR/SPC25/ZFP36L2/ADAMTS1/XPC/LSM11/APPL1/CUL4B/PRMT2/BRSK1/MRNIP/DBF4B/RPL26/ERCC3/TERT/BRD7/WEE1/RRM1/RFWD3/BUB1/AVEN/CDK1/TRIAP1/RRM2/NABP1/ZWILCH/CTDSP2/AURKB/RCC2/CACNB4/PLCB1/CHEK2/FOXO4/CDK10/MUC1/PBX1/ZFP36L1/ARID2/KANK2/TFDP1/GIGYF2/PRKDC/SMARCB1/PTEN 100
GO:1902806 regulation of cell cycle G1/S phase transition 63/3662 160/15509 5.89736e-06 5.51309e-05 3.31548e-05 KMT2E/PAF1/FHL1/ARID1B/ATP2B4/ACTB/PSME1/CDC6/BCL7C/SMARCB1/APEX1/CASP2/EZH2/SMARCD2/CCL2/CCND1/BCL7A/CCND3/PPP2CA/ID2/ARID1A/PKD2/INHBA/CDKN1A/PSME3/MEN1/CCNH/APC/RDX/RB1/CUL4A/CYP1A1/CTDSP1/PLK2/EGFR/ADAMTS1/LSM11/APPL1/CUL4B/PRMT2/RPL26/TERT/BRD7/WEE1/RRM1/RFWD3/MN1/TRIAP1/RRM2/CTDSP2/CACNB4/PLCB1/CHEK2/CDK10/MUC1/ARID2/KANK2/TFDP1/GIGYF2/PRKDC/SMARCB1/PAGR1/PTEN 63
GO:0045023 G0 to G1 transition 22/3662 38/15509 5.94167e-06 5.5295e-05 3.32535e-05 ARID1B/ACTB/BCL7C/SMARCB1/SMARCD2/BCL7A/ARID1A/SOX15/BRD7/RRM1/RHNO1/FOXO4/ARID2/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/SMARCB1/HLA-G 22
GO:1901099 negative regulation of signal transduction in absence of ligand 22/3662 38/15509 5.94167e-06 5.5295e-05 3.32535e-05 SNAI2/GATA1/EYA1/IL7/UNC5B/EYA4/IL1A/IL1B/COL2A1/PF4/TERT/CSF2/PRDX2/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 22
GO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand 22/3662 38/15509 5.94167e-06 5.5295e-05 3.32535e-05 SNAI2/GATA1/EYA1/IL7/UNC5B/EYA4/IL1A/IL1B/COL2A1/PF4/TERT/CSF2/PRDX2/BCL2L1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 22
GO:0010508 positive regulation of autophagy 51/3662 122/15509 6.19048e-06 5.73013e-05 3.446e-05 BAD/DCN/UFL1/ROCK1/MID2/GSK3B/ATG16L1/SH3GLB1/NPRL3/TSC2/MEFV/GSK3A/NOD1/TRIM14/IFNG/IL4/SNX4/TMEM59/PARK7/ELAPOR1/FOXO3/BECN1/KDR/SESN2/TRIM5/TRIM22/PRKAA1/TRIM65/PLK2/C9orf72/SESN3/FOXO1/BAG3/HSPB8/BCL2L11/FYCO1/TP53INP1/NOD2/TRIM68/ADRB2/TRIM8/ORMDL3/KAT5/ATG13/PRKN/HMGB1/DAPK1/SVIP/TRIM13/IKBKG/PIP4K2B 51
GO:0044772 mitotic cell cycle phase transition 129/3662 386/15509 6.19371e-06 5.73013e-05 3.446e-05 CDC27/KMT2E/USH1C/DBF4/SPAST/FHL1/ARID1B/SIRT2/ACTB/NDC80/ABCB1/ZW10/ANAPC5/BIRC5/PSME1/CDC6/CDC7/BCL7C/SMARCB1/CDKN3/APEX1/CDC25B/CHMP4B/RBBP8/RAB11A/NBN/ERCC2/CCNE1/CASP2/EZH2/RPS6KB1/SMARCD2/CCL2/ZPR1/CCND1/BCL7A/FOXM1/FBXO5/CCND3/CCNG1/RAD50/PPP2CA/ID2/CDC20/ARID1A/PKD2/CCNI/PPP6C/MASTL/TEX14/INHBA/CDKN1A/HSPA2/FBXL12/PKMYT1/PSME3/CCNA1/CCNB1/CCNH/CDCA8/APC/RDX/CENPE/NABP2/RB1/CUL4A/CYP1A1/APP/ENSA/DTL/INTS3/CALM2/CTDSP1/CCNA2/PLK2/EGFR/ITGB1/CACUL1/SPC25/ZFP36L2/ADAMTS1/XPC/LSM11/APPL1/CUL4B/CALM3/PRMT2/BRSK1/MRNIP/DBF4B/RPL26/GFI1/ERCC3/TERT/CDK5/BRD7/WEE1/RRM1/RFWD3/BUB1/AVEN/CDK1/PPM1D/TRIAP1/RRM2/KLF11/CKS1B/NABP1/ZWILCH/BRSK2/CTDSP2/CCNE2/AURKB/RCC2/CACNB4/PLCB1/CHEK2/FOXO4/CDK10/MUC1/PBX1/ZFP36L1/ARID2/KANK2/TFDP1/GIGYF2/PRKDC/SMARCB1/PTEN 129
GO:0002678 positive regulation of chronic inflammatory response 13/3662 17/15509 6.20348e-06 5.73013e-05 3.446e-05 TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA 13
GO:0031642 negative regulation of myelination 13/3662 17/15509 6.20348e-06 5.73013e-05 3.446e-05 TMEM98/CTSC/TNFRSF21/EIF2AK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTEN 13
GO:0042368 vitamin D biosynthetic process 13/3662 17/15509 6.20348e-06 5.73013e-05 3.446e-05 SNAI2/CYP27B1/IFNG/CYP3A4/GFI1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 13
GO:0002883 regulation of hypersensitivity 12/3662 15/15509 6.46879e-06 5.9663e-05 3.58803e-05 BTK/FCGR2B/C3/CCR7/ZP3/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 12
GO:0044770 cell cycle phase transition 154/3662 476/15509 6.51928e-06 5.99622e-05 3.60602e-05 CDC27/UPF1/KMT2E/USH1C/DBF4/PAF1/CRY1/SPAST/FHL1/USP28/ARID1B/RAD51/ATP2B4/SIRT2/ACTB/NDC80/PTPRC/ABCB1/ZW10/ANAPC5/BIRC5/PSME1/CDC6/MSH2/CDC7/BCL7C/SMARCB1/CDKN3/APEX1/CDC25B/CHMP4B/RBBP8/RAB11A/NBN/ERCC2/DOT1L/CCNE1/CASP2/EZH2/RPS6KB1/SMARCD2/CCL2/ZPR1/CCND1/BCL7A/FOXM1/FBXO5/MAPK14/CCND3/CCNG1/RAD50/PPP2CA/MACROH2A1/ID2/CDC20/ARID1A/PKD2/CCNI/PPP6C/MASTL/TEX14/INHBA/CDKN1A/HSPA2/FBXL12/PKMYT1/PSME3/CCNA1/MEN1/CCNB1/CCNH/CDCA8/APC/RDX/CENPE/NABP2/BRCA2/RB1/CUL4A/CYP1A1/APP/ENSA/DTL/DYRK3/INTS3/CALM2/CTDSP1/CCNA2/PLK2/EGFR/ITGB1/CACUL1/SPC25/ZFP36L2/ADAMTS1/XPC/EME1/LSM11/APPL1/CUL4B/CALM3/PRMT2/BRSK1/MRNIP/DBF4B/RPL26/GFI1/ERCC3/TERT/CDK5/BRD7/WEE1/RRM1/RFWD3/MN1/BUB1/AVEN/CDK1/PPM1D/TRIAP1/RHNO1/RRM2/KLF11/CKS1B/NABP1/ZWILCH/BRSK2/CTDSP2/CCNE2/AURKB/RCC2/PTPN11/MAPK15/NPM1/CACNB4/PLCB1/CEP63/CHEK2/FOXO4/CDK10/MUC1/PBX1/ZFP36L1/UBE2L3/H2AX/ARID2/KANK2/TFDP1/GIGYF2/PRKDC/PTPRC/SMARCB1/PAGR1/PTEN 154
GO:0030324 lung development 69/3662 180/15509 6.52057e-06 5.99622e-05 3.60602e-05 ITGA3/FLT4/FGFR2/CDC42/GLI2/TP73/HSPB11/PGR/ADAMTS2/RBBP9/BAG6/LAMA1/HOXA5/AIMP2/BMPR1A/PDGFRB/NPHP3/WNT5A/HES1/EPAS1/ARG1/THRA/ELK1/KDR/LIF/ALDH1A2/FOXJ1/LAMA5/AP3B1/CHI3L1/SFTPD/KRAS/PDGFRA/SPRY2/NKX2-1/FGF2/CYP1A2/NOTCH1/THRB/NODAL/MMP14/SELENON/TGFBR2/SHH/NOS3/ABCA3/RBPJ/NKIRAS2/ZFPM2/DAG1/SMAD2/NOG/WNT7B/MME/NKIRAS1/BAG6/TNF/TNF/TNF/TNF/BAG6/TNF/TNF/BAG6/TNF/TNF/BAG6/BAG6/CEBPA 69
GO:0043409 negative regulation of MAPK cascade 61/3662 154/15509 6.5891e-06 6.05026e-05 3.63852e-05 PAFAH1B1/HYAL2/RPS6KA6/FBLN1/PTPRC/MECOM/P2RX7/PEBP1/ABL1/BMP7/CSK/SFRP1/FKTN/AMBP/FOXM1/SH2B3/ASH1L/IL1B/BMP2/PRMT1/PIN1/LIF/APOE/EPHB2/MEN1/PTPN22/SPRY2/TLR4/SORL1/DUSP5/IGF1R/SMAD4/DUSP10/FOXO1/CNKSR3/UCHL1/DUSP2/ATF3/RNF149/PRKCD/DUSP7/GPER1/NDRG2/RGS14/EFNA1/DAG1/PTPN2/ADIPOQ/PRKN/NF2/LILRB4/C1QL4/SPRY4/PPIA/SPRED2/PTPRC/LILRB4/LILRB4/LILRB4/PTEN/ITCH 61
GO:0046636 negative regulation of alpha-beta T cell activation 25/3662 46/15509 6.59935e-06 6.0507e-05 3.63879e-05 HFE/RUNX3/FOXP3/CBFB/TBX21/IL4R/ARG2/SMAD7/LILRB1/JAK3/IL4/BCL6/TWSG1/NDFIP1/HLX/RUNX1/SHH/LGALS9/SOCS1/HMGB1/LILRB1/LILRB1/LILRB1/LILRB1/ITCH 25
GO:0021782 glial cell development 47/3662 110/15509 6.98173e-06 6.39184e-05 3.84394e-05 CNTN1/GRN/SIRT2/ARHGEF10/ERCC2/CNTNAP1/MDK/IFNG/EIF2B2/CLU/LRP1/SOX4/MYRF/IL1B/NKX2-2/NR1D1/WASF3/KRAS/TSPAN2/IL6/TLR4/SOD1/APP/NTRK2/PARD3/SKI/B4GALT5/MXRA8/SLC25A46/SHH/CDK5/LAMB2/DAG1/KCNJ10/PLEC/CNTN2/POU3F2/ROR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTEN 47
GO:0042104 positive regulation of activated T cell proliferation 17/3662 26/15509 7.0376e-06 6.43349e-05 3.86899e-05 IGF1/IL12RB1/PYCARD/IL27RA/JAK3/IL12B/IGFBP2/GPAM/TNFSF9/EPO/IL2RA/IL18/ICOSLG/FADD/STAT5B/HMGB1/CD24 17
GO:0045123 cellular extravasation 36/3662 77/15509 7.18123e-06 6.55512e-05 3.94214e-05 ITGAL/SELE/ROCK1/ADD2/ICAM1/IL27RA/PIK3CG/CXCL12/CCL2/MDK/ITGA4/CCL21/ITGB1/VCAM1/FADD/CX3CR1/PTAFR/SELP/LEP/PLCB1/FUT4/PRTN3/CD47/ELANE/TNF/CD177/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PECAM1/ELANE/PRTN3 36
GO:0046849 bone remodeling 37/3662 80/15509 7.36388e-06 6.71196e-05 4.03645e-05 WNT16/CD38/NOX4/P2RX7/RASSF2/ACP5/CSK/SFRP1/IL7/TGFB1/HAMP/PTN/MDK/CALCA/LEPR/TNFAIP3/SPP1/PTK2B/IAPP/NOTCH2/IL6/DEF8/TNFRSF11A/EPHA2/GJA1/PRKCA/TNFRSF11B/SYK/INPP5D/ADRB2/S1PR1/GPR137/LEP/CSF1R/SRC/ITGB3/INPP5D 37
GO:0071229 cellular response to acid chemical 38/3662 83/15509 7.49632e-06 6.82264e-05 4.10302e-05 RRAGD/CYBA/IPO5/MMP2/XBP1/LAMTOR3/PKD2/DNMT3A/BCL2L2/ASS1/SESN2/DNMT1/PDGFRA/PDGFC/EGFR/NTRK2/ZEB1/SESN3/CAPN2/CYBB/NSMF/BCL2L1/CEBPB/SLC38A9/PLEC/SOCS1/LAMTOR4/COL4A6/MTOR/TNF/TNF/SIPA1/TNF/TNF/TNF/TNF/TNF/TNF 38
GO:0034614 cellular response to reactive oxygen species 53/3662 129/15509 7.542e-06 6.85415e-05 4.12197e-05 MPO/BTK/HGF/GLRX2/MMP2/PXN/ABL1/APEX1/MMP9/BMP7/MET/EZH2/MAPK8/PPIF/PARK7/PRDX1/TNFAIP3/ARG1/FOXO3/PKD2/NR4A3/CAT/BECN1/TRAP1/PRKAA1/PDGFRA/CD36/IL6/IL10/IL18BP/CYP1B1/SOD1/RHOB/EGFR/FANCC/FABP1/PRKCD/NOS3/FXN/PRDX2/CDK1/FOS/RELA/JUN/ERN1/NQO1/AKR1C3/SRC/MAP3K5/ZNF277/ZNF580/CHUK/PCGF2 53
GO:0007163 establishment or maintenance of cell polarity 79/3662 214/15509 7.67769e-06 6.96725e-05 4.18998e-05 PAFAH1B1/ANK1/SDCCAG8/RHOA/ROCK1/CDC42/WDR1/MARK2/FBXW11/NDE1/LLGL2/ACTB/SPAG5/NDC80/DLG3/GSK3B/RAB10/ZW10/NSFL1C/HSP90AB1/ABL1/MYH9/FERMT1/LAMA1/PARD6A/RPGRIP1L/GATA3/CYTH1/LIN7A/CAP2/NPHP3/AMOTL2/WNT5A/HES1/SFRP5/TEK/PDZD11/PTK2B/CCR7/PLEKHG3/RAC2/FOXJ1/CAP1/FLOT2/SPRY2/CCL21/NUMA1/ACTR2/IGF1R/KIF2C/ABL2/SNX27/RHOB/MSN/GSN/PARD3/ITGB1/DST/GJA1/ARHGAP35/BRSK1/LMNA/ARPC5/RICTOR/SHH/TTC8/WEE1/RHOH/PTK2/PDCD6IP/CCL19/KAT5/BRSK2/WNT7B/PARVA/CCL4/CCL4/NDE1/CCL4 79
GO:0043524 negative regulation of neuron apoptotic process 58/3662 145/15509 7.72578e-06 6.99697e-05 4.20785e-05 GRN/HIPK2/ERBB3/MAP2K4/RHOA/ROCK1/BAX/KDM2B/AARS1/MSH2/HSP90AB1/ADNP/IL27RA/GPI/UNC5B/CCL2/ZPR1/CCND1/MDK/PARK7/PTK2B/CNTFR/KDR/APOE/KRAS/NGF/IL10/STXBP1/MAP3K12/ARRB2/SOD1/NONO/NTRK2/POU4F1/NR4A2/BTG2/TERT/FOXQ1/CX3CR1/SEMA3E/BCL2L1/CEBPB/LIG4/HRAS/BDNF/JUN/F2R/PRKN/CLN3/FZD9/SYNGAP1/NTRK1/GPRASP3/NAIP/NAIP/NEFL/NAIP/GPI 58
GO:0042987 amyloid precursor protein catabolic process 30/3662 60/15509 7.73301e-06 6.99697e-05 4.20785e-05 IGF1/ROCK1/PICALM/FKBP1A/GSK3A/IFNG/CLU/PIN1/APOE/FLOT2/RTN3/ADAM19/SORL1/RTN1/PSEN2/NTRK2/SLC2A13/CASP3/EFNA1/RELA/CLN3/TNF/PSENEN/TNF/TNF/TNF/TNF/TNF/TNF/TNF 30
GO:0001774 microglial cell activation 26/3662 49/15509 7.76459e-06 7.00508e-05 4.21273e-05 TYROBP/GRN/PTPRC/CTSC/IFNG/IL4/CLU/NR1D1/SYT11/IL6/APP/ITGB2/TLR3/CX3CR1/ITGAM/JUN/TRPV1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC 26
GO:0034205 amyloid-beta formation 26/3662 49/15509 7.76459e-06 7.00508e-05 4.21273e-05 IGF1/ROCK1/PICALM/GSK3A/IFNG/CLU/PIN1/APOE/RTN3/SORL1/RTN1/PSEN2/NTRK2/SLC2A13/CASP3/EFNA1/RELA/TNF/PSENEN/TNF/TNF/TNF/TNF/TNF/TNF/TNF 26
GO:0018022 peptidyl-lysine methylation 52/3662 126/15509 7.85772e-06 7.0788e-05 4.25707e-05 NFYA/KDM1A/KMT2E/ARID4B/KDM4A/NFYC/ATRX/DNMT3B/SMARCB1/SETD6/DOT1L/EZH2/GATA3/EZH1/NSD2/HCFC2/MACROH2A1/KDM3A/ASH1L/MYB/PHF19/EEF1AKMT3/H1-3/ASH2L/PRDM12/DNMT1/MEN1/SKIC8/SMAD4/BOD1/OGT/NSD3/LMNA/GFI1/PYGO2/NSD1/NNMT/SETD5/H1-4/HCFC1/TRMT112/SETD2/SETD3/KMT5A/TET3/H1-2/PAX5/WDR5/WDR5B/NCOA6/SMARCB1/PAGR1 52
GO:0035107 appendage morphogenesis 57/3662 142/15509 8.12909e-06 7.29148e-05 4.38497e-05 HOXA11/BAK1/ALX4/FGFR2/PITX1/TP63/PLXNA2/TULP3/HOXA9/ATRX/BAX/BMP7/RPGRIP1L/LMBR1/BMPR1A/FBXW4/DKK1/WNT3/ZBTB16/WNT5A/PRRX1/HDAC1/RECK/SOX4/RUNX2/HOXD9/ALDH1A2/NOTCH2/LRP4/TFAP2A/FBN2/COL2A1/RNF165/SMAD4/CRABP2/AFF3/GNA12/NOTCH1/FREM2/MBNL1/BCL2L11/SKI/SHH/RARG/NOG/PBX1/ZNF358/PBX2/PBX2/SP9/PBX2/PBX2/PBX2/PBX2/HOXA10/WNT3/WNT3 57
GO:0035108 limb morphogenesis 57/3662 142/15509 8.12909e-06 7.29148e-05 4.38497e-05 HOXA11/BAK1/ALX4/FGFR2/PITX1/TP63/PLXNA2/TULP3/HOXA9/ATRX/BAX/BMP7/RPGRIP1L/LMBR1/BMPR1A/FBXW4/DKK1/WNT3/ZBTB16/WNT5A/PRRX1/HDAC1/RECK/SOX4/RUNX2/HOXD9/ALDH1A2/NOTCH2/LRP4/TFAP2A/FBN2/COL2A1/RNF165/SMAD4/CRABP2/AFF3/GNA12/NOTCH1/FREM2/MBNL1/BCL2L11/SKI/SHH/RARG/NOG/PBX1/ZNF358/PBX2/PBX2/SP9/PBX2/PBX2/PBX2/PBX2/HOXA10/WNT3/WNT3 57
GO:0051092 positive regulation of NF-kappaB transcription factor activity 57/3662 142/15509 8.12909e-06 7.29148e-05 4.38497e-05 DHX33/BTK/LTF/EIF2AK2/TRAF1/MID2/ERC1/PSMA6/CD40/CD40LG/PYCARD/PRKD2/MTPN/NOD1/TRIM14/WNT5A/CLU/TRIM25/CAT/IL1B/RBCK1/EDA2R/TRIM5/TRIM22/FLOT2/CD36/TLR4/TNFRSF11A/APP/IL18/TLR3/NOD2/TRIM68/CX3CR1/LGALS9/ALK/TRIM8/RELA/NPM1/IRAK1/CIB1/ROR1/CARD9/IL1RAP/PPIA/NTRK1/TNF/TRIM13/TNF/CHUK/TNF/TNF/TNF/TNF/TNF/TNF/IKBKG 57
GO:0071675 regulation of mononuclear cell migration 51/3662 123/15509 8.17185e-06 7.31923e-05 4.40166e-05 SPI1/RHOA/ABL1/PYCARD/IL27RA/SERPINE1/CREB3/CXCL12/C1QBP/CCL2/MDK/NEDD9/IL4/WNT5A/CCL20/ITGA4/PADI2/PTK2B/CCR7/CCN3/CCL21/THBS1/APP/ABL2/SLIT2/MSN/CXCL13/FADD/CX3CR1/LGALS9/PTK2/CALR/CSF1R/PLCB1/CSF1/HMGB1/CD47/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/CCL5/CCL5/CCL4/CCL4/CCL4 51
GO:0042698 ovulation cycle 31/3662 63/15509 8.35577e-06 7.47317e-05 4.49423e-05 HSPA5/PGR/OPRK1/MMP2/ESR1/ADNP/PTN/CASP2/MAP2K6/MDK/FOXO3/EGR1/INHBA/PDGFRA/CYP1B1/IGF1R/ARRB2/SLIT2/GAS2/ADAMTS1/CASP3/GDF9/NOS3/STAT5B/LEP/FZD4/A2M/OXTR/SLIT3/ZP3/SRC 31
GO:0030326 embryonic limb morphogenesis 50/3662 120/15509 8.48204e-06 7.56427e-05 4.54902e-05 HOXA11/ALX4/PITX1/TP63/TULP3/HOXA9/BAX/BMP7/RPGRIP1L/LMBR1/BMPR1A/FBXW4/DKK1/WNT3/ZBTB16/WNT5A/PRRX1/HDAC1/RECK/RUNX2/HOXD9/ALDH1A2/NOTCH2/LRP4/TFAP2A/FBN2/SMAD4/CRABP2/AFF3/GNA12/NOTCH1/FREM2/MBNL1/BCL2L11/SKI/SHH/RARG/NOG/PBX1/ZNF358/PBX2/PBX2/SP9/PBX2/PBX2/PBX2/PBX2/HOXA10/WNT3/WNT3 50
GO:0035113 embryonic appendage morphogenesis 50/3662 120/15509 8.48204e-06 7.56427e-05 4.54902e-05 HOXA11/ALX4/PITX1/TP63/TULP3/HOXA9/BAX/BMP7/RPGRIP1L/LMBR1/BMPR1A/FBXW4/DKK1/WNT3/ZBTB16/WNT5A/PRRX1/HDAC1/RECK/RUNX2/HOXD9/ALDH1A2/NOTCH2/LRP4/TFAP2A/FBN2/SMAD4/CRABP2/AFF3/GNA12/NOTCH1/FREM2/MBNL1/BCL2L11/SKI/SHH/RARG/NOG/PBX1/ZNF358/PBX2/PBX2/SP9/PBX2/PBX2/PBX2/PBX2/HOXA10/WNT3/WNT3 50
GO:0030856 regulation of epithelial cell differentiation 56/3662 139/15509 8.54325e-06 7.60791e-05 4.57526e-05 BAD/PROM1/ROCK1/TP63/TP73/ADD1/MMP9/BMP7/ESRP1/SERPINE1/EZH2/SFRP4/GATA3/CCND1/CYP27B1/VDR/IFNG/MACROH2A1/HES1/IL1A/STAT1/IL1B/NKX2-2/BMP2/ID1/ZFP36/LIF/FOXJ1/BTG1/KRAS/AHI1/SPRY2/NUMA1/FGF2/NOTCH1/ZEB1/BMP6/NODAL/FRZB/AQP3/CEBPB/STAT5B/ZDHHC21/PLCB1/ZFP36L1/MAFG/SPRED2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CD24 56
GO:0031641 regulation of myelination 27/3662 52/15509 8.89035e-06 7.88474e-05 4.74174e-05 TMEM98/HGF/TNFRSF1B/SIRT2/PTN/CTSC/ZPR1/EGR2/MYRF/RARA/WASF3/ITGAX/TNFRSF21/PARD3/EIF2AK3/RARG/DAG1/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTEN 27
GO:0036230 granulocyte activation 27/3662 52/15509 8.89035e-06 7.88474e-05 4.74174e-05 KMT2E/TYROBP/GRN/KARS1/SPI1/FCGR2B/STXBP2/CTSG/IL18/ITGB2/PRKCD/SYK/PTAFR/CXCL8/ITGAM/CXCR2/TNF/CD177/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CCL5/CCL5 27
GO:0034113 heterotypic cell-cell adhesion 32/3662 66/15509 8.90499e-06 7.88474e-05 4.74174e-05 CD44/PKP2/PTPRC/CEACAM6/DSP/BMP7/PERP/ITGA4/IL1B/IL10/IL1RN/ITGAV/ITGAX/ITGB1/ITGB2/VCAM1/FGG/FGA/ADIPOQ/CD47/PARVA/MBP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/PTPRC 32
GO:1901224 positive regulation of NIK/NF-kappaB signaling 32/3662 66/15509 8.90499e-06 7.88474e-05 4.74174e-05 EIF2AK2/RHOA/NFAT5/NOD1/IL12B/CD86/IL1B/RBCK1/TLR4/APP/EGFR/IL18/TLR3/TRIM44/NOD2/LGALS9/LIMS1/CD14/CCL19/RELA/CALR/IRAK1/PTP4A3/TLR7/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 32
GO:0061042 vascular wound healing 16/3662 24/15509 9.10654e-06 8.05169e-05 4.84215e-05 ADIPOR2/MCAM/XBP1/SERPINE1/SMOC2/TNFAIP3/CXCR4/KDR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 16
GO:0009266 response to temperature stimulus 70/3662 185/15509 9.46079e-06 8.35299e-05 5.02334e-05 IGF1/GLRX2/NGFR/ATXN3/PRKACA/ACADVL/GSK3B/HSP90AB1/CIRBP/NFKBIA/RBBP7/DNAJB6/HSPB1/CXCL12/RPS6KB1/CRYAB/CHORDC1/CALCA/IL1A/EIF2B2/CXCR4/THRA/HSPA2/PRDM12/PRKAA1/THBS1/ARRB2/SOD1/PKLR/POLR2D/STAC/FOXO1/BAG3/SLC25A27/NR2F6/CLPB/IER5/MAPKAPK2/NOS3/TP53INP1/VCP/ADRB2/FOS/CD14/EIF2AK3/LPL/MICA/IRAK1/TRPV1/NTRK1/MTOR/DAXX/DAXX/MICB/MICB/HSBP1L1/DAXX/MICB/DAXX/MICB/MICA/MICB/DAXX/MICA/MICA/MICB/PDCD6/PKLR/CHORDC1/PRKACA 70
GO:0014909 smooth muscle cell migration 34/3662 72/15509 9.7702e-06 8.61389e-05 5.18025e-05 IGF1/RHOA/PDGFB/APEX1/NDRG4/PLAT/SERPINE1/BMPR1A/RPS6KB1/MDK/PPARD/PDGFRB/NR4A3/GNA13/LRP1/TLR4/CCN3/SORL1/CYP1B1/SLIT2/GNA12/IGFBP3/ADAMTS1/ARPC5/S100A11/TERT/DDIT3/ADIPOQ/FOXO4/SRC/PARVA/ITGB3/CCL5/CCL5 34
GO:0061900 glial cell activation 28/3662 55/15509 9.95013e-06 8.76007e-05 5.26815e-05 TYROBP/GRN/PTPRC/CTSC/IFNG/IL4/CLU/LRP1/IL1B/NR1D1/SYT11/IL6/APP/ITGB2/TLR3/CX3CR1/ITGAM/JUN/TRPV1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC 28
GO:0002064 epithelial cell development 75/3662 202/15509 1.01952e-05 8.96309e-05 5.39025e-05 BAD/FOXP3/ARID4B/PRDM1/ROCK1/TP63/FOSL2/PGR/GSK3B/ATRX/ADD1/ICAM1/ESR1/PDGFB/PPP1R16B/GATA1/TJP1/GSK3A/MET/HOXA5/RAPGEF1/ACTA2/WNT5B/PDE4D/WNT5A/IL1A/SDC1/EPAS1/CXCR4/IL1B/NKX2-2/BCL11B/KDR/PODXL/FOXJ1/RARA/HSD17B4/NOTCH2/EDNRB/CCM2/RDX/ABI2/EPHA2/RAB13/MSN/NOTCH1/BMP6/STC1/FRZB/FRS2/CDH2/LAMB2/RARG/ZDHHC21/TYMS/PLEC/ADIPOQ/YIPF6/PLCB1/COL18A1/MAGI2/WNT7B/SRC/NTRK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/PECAM1/TJP1 75
GO:0033627 cell adhesion mediated by integrin 37/3662 81/15509 1.04941e-05 9.21278e-05 5.5404e-05 ITGAL/ITGA3/ITGA2B/SNAI2/EPHA8/ITGA8/ICAM1/FERMT1/PIEZO1/PIK3CG/SERPINE1/LPXN/ITGA4/LIF/PODXL/CCN3/CCL21/ITGA11/CYP1B1/ITGAV/ITGAX/EPHA2/ITGB1/CXCL13/ITGB2/SYK/ADAM9/EFNA1/PTK2/ITGAM/PTPN11/CIB1/MUC1/DPP4/ITGB3/CCL5/CCL5 37
GO:0001938 positive regulation of endothelial cell proliferation 41/3662 93/15509 1.05469e-05 9.24607e-05 5.56043e-05 FLT4/CYBA/SIRT6/FGFR1/PDGFB/PPP1R16B/PRKD2/TGFBR1/CXCL12/MDK/WNT5A/ITGA4/PDCL3/NRP2/ARG1/PGF/TEK/NR4A1/BMP2/STAT5A/KDR/IL10/FGF2/EGF/ARNT/VEGFC/BMP6/PRKCA/EMC10/AGGF1/SCG2/CCL11/EGFL7/JUN/HMGB1/NRARP/ZNF580/NRAS/PDCD6/ITGB3/AKT3 41
GO:0046629 gamma-delta T cell activation 22/3662 39/15509 1.05956e-05 9.26253e-05 5.57032e-05 PTPRC/LILRB1/SOX4/SYK/NOD2/CCR9/STAT5B/MICA/MICB/MICB/MICB/MICB/MICA/MICB/MICA/MICA/MICB/PTPRC/LILRB1/LILRB1/LILRB1/LILRB1 22
GO:0150077 regulation of neuroinflammatory response 22/3662 39/15509 1.05956e-05 9.26253e-05 5.57032e-05 IGF1/TNFRSF1B/GRN/PTPRC/MMP9/CTSC/IL4/IL1B/NR1D1/SYT11/DAGLA/IL6/IL18/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC 22
GO:0050871 positive regulation of B cell activation 40/3662 90/15509 1.0616e-05 9.26729e-05 5.57319e-05 BAD/CD38/BTK/CD74/TBX21/MLH1/PTPRC/MSH2/XBP1/CD40/NFATC2/IL7/TGFB1/EXOSC3/NSD2/CD81/IL4/IL5/BCL6/SHLD2/CDKN1A/EPHB2/AKIRIN2/IL6/IL10/TLR4/IL21/IL2RG/MMP14/TNFRSF13C/TNFSF13/SYK/NOD2/TNIP2/INPP5D/STAT5B/CD28/PTPRC/MIF/INPP5D 40
GO:0033135 regulation of peptidyl-serine phosphorylation 51/3662 124/15509 1.07268e-05 9.35086e-05 5.62345e-05 HGF/CD44/BAK1/FNIP2/ATP2B4/BAX/HSP90AB1/OSM/TCL1A/RASSF2/SMAD7/AXIN1/PRKD2/TGFB1/GSK3A/DKK1/CSF3/IFNG/PDE4D/WNT5A/PARK7/GADD45A/LIF/PRKAA1/NGF/SPRY2/IL6/ARRB2/APP/CNOT9/EGFR/NTRK2/CNKSR3/DMTN/SPTBN4/RICTOR/NSD1/DDIT4/BDNF/INPP5J/IFNA1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MIF/PTEN 51
GO:0031334 positive regulation of protein-containing complex assembly 68/3662 179/15509 1.07997e-05 9.40121e-05 5.65372e-05 DHX33/BAK1/FNIP2/RHOA/NAV3/GSK3B/BAX/ESR1/SH3GLB1/PSMC6/TCL1A/FERMT1/HCK/PIEZO1/PYCARD/MED25/TGFB1/MET/CSF3/IFNG/IL5/PARK7/SLF2/CLU/PTK2B/CCR7/CDC42EP1/AJUBA/PSRC1/HRK/CD36/LCP1/TLR4/CCL21/ATAT1/NUMA1/SLAIN1/WARS1/MSN/CDC42EP2/BCL2L11/GBP5/CXCL13/ALOX15/TAL1/CDC42EP3/RICTOR/CSF2/SYK/VCP/ABCA3/PRKCE/CCL11/CDK5R1/GRB2/DRG1/MMP1/SRC/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/BRK1 68
GO:0032515 negative regulation of phosphoprotein phosphatase activity 18/3662 29/15509 1.10307e-05 9.56883e-05 5.75453e-05 ROCK1/GSK3B/PPP1R15A/FKBP1A/PTPA/MASTL/CRY2/STYXL1/BOD1/TNF/PPP1R11/TNF/TNF/TNF/TNF/TNF/TNF/TNF 18
GO:0051043 regulation of membrane protein ectodomain proteolysis 18/3662 29/15509 1.10307e-05 9.56883e-05 5.75453e-05 TNFRSF1B/ROCK1/SH3D19/IFNG/IL1B/APOE/IL10/FURIN/ADAM9/RGMA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 18
GO:0051091 positive regulation of DNA-binding transcription factor activity 87/3662 243/15509 1.10386e-05 9.56883e-05 5.75453e-05 KDM1A/DHX33/BTK/MBTPS2/LTF/EIF2AK2/TRAF1/HIPK2/TCF3/MID2/ERC1/MAVS/ESR1/SMARCB1/PSMA6/CD40/CD40LG/PYCARD/PRKD2/MTPN/NOD1/TRIM14/CSF3/IL5/WNT5A/PARK7/CLU/TRIM25/CAT/IL1B/RBCK1/BMP2/EDA2R/TRIM5/TRIM22/FLOT2/BEX1/CD36/IL6/IL10/TLR4/TNFRSF11A/APP/EPHA5/PPRC1/ARID5B/IL18/NODAL/KIT/TLR3/SHH/ADCY1/NOD2/TRIM68/CX3CR1/LGALS9/ALK/TRIM8/RELA/FZD4/DDIT3/FOSL1/NPM1/IRAK1/CIB1/ROR1/RNF220/CARD9/IL1RAP/PPIA/TFDP1/NTRK1/TNF/TRIM13/TNF/CHUK/TNF/TNF/TNF/TNF/TNF/TNF/TRIM26/IKBKG/SMARCB1/LRP6/PTEN 87
GO:0035308 negative regulation of protein dephosphorylation 20/3662 34/15509 1.13549e-05 9.82929e-05 5.91116e-05 ROCK1/GSK3B/PPP1R15A/FKBP1A/PPP1R16B/PTPA/MASTL/CRY2/STYXL1/ENSA/BOD1/TNF/PPP1R11/TNF/TNF/TNF/TNF/TNF/TNF/TNF 20
GO:0034116 positive regulation of heterotypic cell-cell adhesion 15/3662 22/15509 1.1594e-05 0.000100108 6.02034e-05 CD44/CEACAM6/BMP7/IL1B/IL10/FGG/FGA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:0000018 regulation of DNA recombination 49/3662 118/15509 1.16131e-05 0.000100108 6.02034e-05 KDM1A/PARP3/FOXP3/RAD51/TBX21/ACTB/MLH1/SIRT6/PTPRC/FUS/MSH2/CD40/RBBP8/ERCC2/IL27RA/TGFB1/EXOSC3/RECQL5/NSD2/IL4/RAD50/BCL6/KPNA1/SHLD2/MORF4L2/H1-3/YEATS4/NDFIP1/EPC2/IL10/ACTR2/SLC15A4/PARP1/RADX/PPP4C/MRNIP/TNFSF13/H1-4/KAT5/RMI2/MAGEF1/CD28/SETD2/H1-2/H1-0/ARID2/TRRAP/RTEL1/PTPRC 49
GO:0051101 regulation of DNA binding 49/3662 118/15509 1.16131e-05 0.000100108 6.02034e-05 KDM1A/IGF1/HIPK2/SP100/SIRT2/ZMPSTE24/NFKBIA/MMP9/GATA1/ERCC2/DOT1L/TGFB1/EDF1/GATA3/MAPK8/IFNG/HES1/PARK7/ID1/LIF/PER2/NGF/IRF4/EGF/RB1/PARP1/CALM2/HMGA2/POU4F2/POU4F1/SKI/CALM3/NSD1/DDIT3/JUN/CTNNBIP1/SUMO3/PRKN/RNF220/H1-0/HMGB1/CSNK2B/TMSB4X/CPNE1/CSNK2B/CSNK2B/CSNK2B/CSNK2B/NME1 49
GO:0006879 cellular iron ion homeostasis 30/3662 61/15509 1.17968e-05 0.00010127 6.09019e-05 HFE/SLC11A1/ATP6AP1/SLC46A1/FTL/SLC22A17/NUBP1/SLC39A14/HAMP/TFR2/HPX/SLC11A2/IFNG/ATP6V1A/NDFIP1/ISCU/IREB2/ATP6V1G1/SMAD4/SOD1/LCN2/BMP6/STEAP2/ALAS2/CYB561A3/FXN/FTH1/ERFE/TMPRSS6/TMEM199 30
GO:0042093 T-helper cell differentiation 30/3662 61/15509 1.17968e-05 0.00010127 6.09019e-05 TMEM98/FOXP3/TBX21/IL4R/IL12RB1/SMAD7/JAK3/GATA3/IL12B/IL4/BCL6/CD86/MYB/CD80/RARA/IL6/HLX/IRF4/IL21/IL18/IL6R/CCL19/HMGB1/ENTPD7/MTOR/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 30
GO:0051310 metaphase plate congression 30/3662 61/15509 1.17968e-05 0.00010127 6.09019e-05 CENPQ/MLH1/SPAG5/NDC80/PIBF1/SEH1L/CHMP5/ZW10/BIRC5/NUDC/CHMP4B/RAB11A/KAT2B/TTL/BECN1/CHMP1A/CCNB1/PSRC1/CDCA8/NUMA1/CENPE/KIF2C/CENPC/BOD1/GEM/KAT5/CHMP6/AURKB/KIFC1/SPICE1 30
GO:2001238 positive regulation of extrinsic apoptotic signaling pathway 26/3662 50/15509 1.25556e-05 0.000107527 6.46648e-05 HYAL2/PTPRC/SRPX/PYCARD/SFRP1/TNFSF10/INHBA/RBCK1/ITM2C/THBS1/PMAIP1/PEA15/ATF3/GPER1/FADD/PAK2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC/PTEN 26
GO:0030888 regulation of B cell proliferation 31/3662 64/15509 1.25604e-05 0.000107527 6.46648e-05 CD38/BTK/TYROBP/CD22/CD74/FCGR2B/PTPRC/CD40/NFATC2/IL7/AHR/CD81/IL4/IL5/BCL6/PKN1/CDKN1A/EPHB2/IL10/TLR4/IL21/TNFRSF21/TNFRSF13C/CTLA4/CASP3/INPP5D/TNFRSF13B/PTPRC/MIF/INPP5D/PTEN 31
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process 71/3662 190/15509 1.34799e-05 0.000115239 6.93029e-05 BAD/CASP10/HGF/BIRC3/FAS/CD44/BAK1/NGFR/RHOA/TP63/BAX/BIRC5/MMP9/BIRC7/PYCARD/PDCD5/GPI/DNAJB6/NOD1/CASP2/CRYAB/HSPE1/PARK7/FASLG/TNFSF10/NR4A1/MICAL1/ANP32B/MTCH1/THBS1/BCL2L10/ARRB2/PMAIP1/CCN1/ARL6IP5/GSN/BCL2L11/NODAL/FABP1/GPER1/INTS1/SYK/VCP/RAG1/LGALS9/MGMT/SERPINB9/TRIAP1/EIF2AK3/PAK2/F2R/CARD9/HMGB1/DAPK1/SRC/MAP3K5/TNF/TNF/FIS1/MAGEA3/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/PDCD6/NAIP/NAIP/GPI 71
GO:0016055 Wnt signaling pathway 135/3662 413/15509 1.35001e-05 0.000115253 6.93112e-05 WNT16/ITGA3/PAF1/SNAI2/PTPRU/CDH3/FGFR2/RHOA/VPS35/CSNK2A2/CDC42/MARK2/FBXW11/GPC4/GSK3B/ABL1/GSKIP/CHD8/FERMT1/AXIN1/TSC2/SFRP1/TLE5/CCNE1/TGFB1/GSK3A/HBP1/SFRP4/SPIN1/DVL1/GATA3/FBXW4/DKK1/RNF43/WNT3/CCND1/FOLR1/MDK/WNT5B/FZD10/MAPK14/PPP2CA/ARL6/NPHP3/AMOTL2/KPNA1/WNT5A/IGFBP2/SDC1/BCL9/HDAC1/TNFAIP3/FOXO3/PKD2/SFRP5/EGR1/RECK/PFDN5/LRP1/SOX4/BMP2/PIN1/APOE/PRKAA1/LRP4/APC/MDFIC/EDNRB/PPM1B/FGF2/EGF/SKIC8/CSNK1D/APP/CELSR2/RBMS3/TPBG/EGFR/NOTCH1/TCF7L2/FOXO1/HHEX/NR4A2/GNAQ/WIF1/SKI/DVL3/WNT4/VANGL2/DISC1/FRZB/PYGO2/TERT/SHH/VCP/AMER2/NDRG2/BRD7/BTRC/NXN/RBPJ/ZEB2/CTNND2/CDH2/RARG/RNF213/FZD4/DDIT3/FOXL1/CTNNBIP1/NKX2-5/NOG/ZNF703/NOTUM/PRKN/ROR1/BCL9L/RNF220/MAGI2/WNT7B/FZD9/SRC/GRK6/NRARP/GRK5/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CD24/WNT3/WNT3/LRP6/PTEN 135
GO:0050810 regulation of steroid biosynthetic process 33/3662 70/15509 1.37444e-05 0.000117177 7.04682e-05 MBTPS2/SNAI2/H6PD/DDX20/APOB/ASAH1/CYP27B1/IFNG/PDE8B/IL1A/EGR1/BMP2/NR1D1/APOE/PRKAA1/IGF1R/ARMC5/SOD1/ERLIN2/BMP6/WNT4/GFI1/ATP1A1/LEP/AKR1C3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 33
GO:0045834 positive regulation of lipid metabolic process 56/3662 141/15509 1.40943e-05 0.000119995 7.21628e-05 CD74/FGFR3/CDC42/EPHA8/PDGFB/EEF1A2/FLT1/TGFB1/CD81/IFNG/PPARD/PDGFRB/IL1A/NR4A3/TEK/PTK2B/FLT3/RAB38/ACSL3/IL1B/CCR7/NR1D1/ATG14/APOE/PRKAA1/PDGFRA/CCL21/FGF2/IGF1R/CCN1/BMP6/KIT/LDLRAP1/WNT4/CAPN2/FABP1/PRKCD/NOD2/PTK2/PRKCE/CCL19/KAT5/CD19/F2/ADIPOQ/KLHL25/SRC/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 56
GO:0032732 positive regulation of interleukin-1 production 34/3662 73/15509 1.4166e-05 0.00012044 7.24305e-05 TYROBP/P2RX7/TLR8/MEFV/PYCARD/NOD1/HSPB1/IFNG/IL17A/WNT5A/EGR1/CD36/IL6/TLR4/APP/GBP5/NOD2/LGALS9/IL16/CCL19/LPL/HMGB1/TNF/TNF/TNF/TNF/TNF/TNF/ORM1/TNF/TNF/NAIP/NAIP/NAIP 34
GO:0009755 hormone-mediated signaling pathway 70/3662 187/15509 1.44437e-05 0.000122263 7.35267e-05 KDM1A/ADIPOR2/CRY1/RNF14/UFL1/PLPP1/RHOA/TP63/PIAS2/PGR/ESR1/RBFOX2/BMP7/SFRP1/ZMIZ1/DDX5/GTF2H1/PPARD/KDM3A/PARK7/HDAC1/NR5A2/PADI2/ARID1A/NR4A3/CRHR1/CRY2/PKN1/CNOT1/THRA/NR1D1/YWHAH/RARA/WBP2/CARM1/PARP1/REN/CNOT9/THRB/POU4F2/NODAL/APPL1/ADIPOR1/PRMT2/HEYL/GPER1/TRIM68/PAQR8/TADA3/CYP7B1/RARG/ESRRA/TAF7/CALR/PTPN11/SSTR2/SRC/KANK2/RXRB/CSNK2B/DAXX/DAXX/CSNK2B/CSNK2B/DAXX/CSNK2B/DAXX/DAXX/CSNK2B/PAGR1 70
GO:0042362 fat-soluble vitamin biosynthetic process 14/3662 20/15509 1.44462e-05 0.000122263 7.35267e-05 SNAI2/CYP27B1/IFNG/UBIAD1/CYP3A4/GFI1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 14
GO:0031589 cell-substrate adhesion 111/3662 328/15509 1.44585e-05 0.000122263 7.35267e-05 ITGAL/ITGA3/ITGA2B/CD44/EPHA3/PKP2/ATXN3/RHOA/ROCK1/CDC42/ST6GAL1/ACTN2/FBLN1/ITGA8/GSK3B/CEACAM6/NID2/PXN/ANGPT2/ABL1/PDGFB/FERMT1/OLFM4/MSLN/SFRP1/SERPINE1/ATRNL1/C1QBP/LPXN/MDK/VWF/CORO1C/NEDD9/PPARD/BVES/BCL6/ITGA4/FN1/TEK/PTK2B/ID1/CCR7/RRAS/KDR/RAC2/HOXD3/AJUBA/LAMA5/PPFIA1/TIMM10B/MEN1/CD36/LAMC1/CCL21/TMEM8B/THBS1/ITGA11/SMAD6/ITGAV/ITGAX/TBCD/CCN1/PIK3R1/NOTCH1/ITGB1/BCL2L11/MERTK/CD96/ABI3BP/MMP14/DMTN/ITGB2/ADAMTS13/COL26A1/ALOX15/WNT4/VCAM1/SNED1/DISC1/MELTF/EDIL3/EGFLAM/CDK5/ADAM9/EFNA1/PTK2/PLEKHA2/ANTXR1/LIMS1/ITGAM/SEMA3E/PRKCE/FGG/FGA/LAMB2/DAG1/FZD4/RCC2/CALR/EPHB3/CSF1/CIB1/NF2/BCAM/SPRY4/SRC/COL13A1/PARVA/ITGB3/ADAMTS13/PTEN 111
GO:0071230 cellular response to amino acid stimulus 35/3662 76/15509 1.4479e-05 0.000122263 7.35267e-05 RRAGD/CYBA/IPO5/MMP2/XBP1/LAMTOR3/DNMT3A/BCL2L2/ASS1/SESN2/DNMT1/PDGFRA/PDGFC/EGFR/NTRK2/ZEB1/SESN3/CAPN2/CYBB/NSMF/BCL2L1/CEBPB/SLC38A9/SOCS1/LAMTOR4/COL4A6/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 35
GO:1900182 positive regulation of protein localization to nucleus 35/3662 76/15509 1.4479e-05 0.000122263 7.35267e-05 CDH1/NGFR/IPO5/HYAL2/MAVS/HSP90AB1/TGFB1/ZPR1/IFNG/MAPK14/PARK7/TARDBP/LIF/SESN2/DKC1/CCT7/PARP1/PIK3R1/BAG3/PRKCD/TERT/SHH/CCT2/CHP2/NMD3/CDK1/TRIM8/ORMDL3/EIF2AK3/LEP/LARP7/F2/NPM1/CACNB4/SRC 35
GO:0019932 second-messenger-mediated signaling 101/3662 293/15509 1.46378e-05 0.000123436 7.42321e-05 SELE/CD4/BTK/PTBP1/CD22/IGF1/ATP2B4/ERBB3/INPP5A/PRKACA/PTPRC/GSK3B/P2RX5/ZMPSTE24/LAT2/P2RX7/RASD2/NFATC2/ADNP/MGRN1/NFAT5/AHR/PPP3CB/CAP2/PDE4D/PPP2CA/CCL20/ZAP70/FHL2/NR5A2/RCAN3/PTK2B/CXCR4/CCR7/DYRK2/KDR/TNNI3/APOE/CAP1/PRKAA1/CD36/EDNRB/THBS1/PLCE1/CALM2/EPHA5/ANK2/EGFR/GSTO1/ITPR1/DDAH1/GPR61/SPPL3/DMTN/CALM3/PDE9A/CXCR5/CCR5/VCAM1/CXCR1/ADCY1/NOS3/SYK/CHP2/CX3CR1/CXCL8/HINT1/PDE7B/KSR2/EIF2AK3/RCAN2/PDE3A/CCR9/SELP/ATP2A2/GRIN1/CXCR2/MAFA/SLC8A1/CCR4/CIB1/CXCR3/P2RX2/MTOR/TNF/TNF/STIMATE/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/P2RY11/PTPRC/LOC102724560/CCL4/CCL4/CCL4/PRKACA 101
GO:0048708 astrocyte differentiation 36/3662 79/15509 1.46895e-05 0.000123703 7.43928e-05 GRN/KDM4A/ABL1/IFNG/HES1/ID2/LRP1/IL1B/NKX2-2/BMP2/NR1D1/LIF/KRAS/TSPAN2/SERPINE2/IL6/TLR4/APP/NOTCH1/CUL4B/SHH/LAMB2/PTPN11/F2/NOG/CNTN2/POU3F2/ROR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 36
GO:1905898 positive regulation of response to endoplasmic reticulum stress 21/3662 37/15509 1.47883e-05 0.000124366 7.47918e-05 BAK1/HERPUD1/ATXN3/FCGR2B/BAX/BAG6/XBP1/SGTA/TMEM33/SERINC3/PMAIP1/PIK3R1/BCL2L11/DDIT3/PTPN2/ERN1/BAG6/BAG6/BAG6/BAG6/BAG6 21
GO:2000116 regulation of cysteine-type endopeptidase activity 78/3662 214/15509 1.48741e-05 0.000124919 7.51239e-05 BAD/CASP10/LTF/HGF/BIRC3/FAS/CD44/BAK1/CYFIP2/NGFR/RHOA/TP63/BAX/BIRC5/MMP9/BIRC7/MEFV/PYCARD/PDCD5/GPI/DNAJB6/NOD1/CASP2/CRYAB/PERP/HSPE1/PARK7/FASLG/TNFSF10/NR4A1/MICAL1/ANP32B/MTCH1/THBS1/BCL2L10/ARRB2/PMAIP1/CCN1/ARL6IP5/GSN/BCL2L11/CAST/NODAL/FABP1/GPER1/INTS1/SYK/VCP/RAG1/FADD/LGALS9/MGMT/SERPINB9/TRIAP1/EIF2AK3/GRIN1/PAK2/F2R/CARD9/HMGB1/DAPK1/SRC/MAP3K5/TNF/TNF/FIS1/MAGEA3/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/PDCD6/NAIP/NAIP/GPI 78
GO:0031330 negative regulation of cellular catabolic process 75/3662 204/15509 1.52257e-05 0.000127698 7.67952e-05 HFE/SLC11A1/HGF/CLEC16A/PHF23/ATP2B4/HIPK2/CTSA/ELAVL1/KDM4A/ROCK1/SIRT2/CSNK2A2/FUS/HNRNPC/BAG6/HSP90AB1/CIRBP/CHMP4B/USP14/N4BP1/TSC2/SNRNP70/SGTA/GSK3A/PIK3CG/MET/TRDMT1/LARP4B/EIF4G2/MAPK14/PDCL3/PARK7/LEPR/SLIRP/NRDE2/TARDBP/USP9X/BECN1/ZFP36/DKC1/TBC1D14/PTPN22/IL10/SORL1/FURIN/TOB1/TLK2/OGT/EIF3H/TAB3/MAPKAPK2/RYBP/SHH/GOLGA2/PAIP1/ANGEL2/LEP/TMEM39A/WDR6/ANXA2/RBM10/USP7/SECISBP2/SVIP/MTOR/RNF5/BAG6/MAGEA3/BAG6/BAG6/BAG6/BAG6/HP/TAF15 75
GO:0000082 G1/S transition of mitotic cell cycle 72/3662 194/15509 1.54345e-05 0.000129274 7.77434e-05 KMT2E/DBF4/FHL1/ARID1B/ACTB/PSME1/CDC6/CDC7/BCL7C/SMARCB1/CDKN3/APEX1/RBBP8/CCNE1/CASP2/EZH2/RPS6KB1/SMARCD2/CCL2/ZPR1/CCND1/BCL7A/CCND3/PPP2CA/ID2/ARID1A/PKD2/PPP6C/INHBA/CDKN1A/PSME3/CCNH/APC/RDX/RB1/CUL4A/CYP1A1/CTDSP1/PLK2/EGFR/ITGB1/CACUL1/ADAMTS1/LSM11/APPL1/CUL4B/PRMT2/RPL26/GFI1/TERT/CDK5/BRD7/WEE1/RRM1/RFWD3/TRIAP1/RRM2/KLF11/CTDSP2/CCNE2/CACNB4/PLCB1/CHEK2/CDK10/MUC1/ARID2/KANK2/TFDP1/GIGYF2/PRKDC/SMARCB1/PTEN 72
GO:0098543 detection of other organism 19/3662 32/15509 1.56437e-05 0.00013085 7.86907e-05 NOD1/TLR4/NOD2/HLA-B/HLA-A/HLA-A/HLA-B/HLA-A/HLA-A/HLA-B/HLA-A/HLA-B/HLA-A/HLA-A/HLA-B/HLA-A/NAIP/NAIP/NAIP 19
GO:0007568 aging 58/3662 148/15509 1.60408e-05 0.000133991 8.05797e-05 MPO/GLRX2/TNFRSF1B/BAK1/HYAL2/MBD3/TP63/MMP2/APEX1/ERCC2/HAMP/GSK3A/CASP2/RPS6KB1/CRYAB/CTSC/CALCA/PDGFRB/IGFBP2/ARG1/FOXO3/DNMT3A/GNA13/SERP1/CAT/INHBA/BECN1/CD68/EPO/ASS1/LOXL2/EDNRB/IL10/FGF2/IGF1R/CYP1A1/RNF165/SMAD4/SOD1/CARM1/GNA12/VCAM1/INHBB/TGFBR2/GPX4/FOS/DAG1/CNP/TYMS/GRB2/AURKB/NQO1/IRAK1/FOXO4/PAX5/MME/MBP/NTRK1 58
GO:1901215 negative regulation of neuron death 74/3662 201/15509 1.63629e-05 0.000136497 8.20869e-05 TNFRSF1B/GRN/HIPK2/ERBB3/MAP2K4/RHOA/ROCK1/INPP5A/VPS35/GSK3B/BAX/SLC23A2/KDM2B/AARS1/MSH2/HSP90AB1/ADNP/CHMP4B/IL27RA/GPI/UNC5B/CSF3/CCL2/ZPR1/CCND1/MDK/PARK7/NENF/NR4A3/PTK2B/CNTFR/KDR/APOE/EPO/KRAS/NGF/IL10/STXBP1/SORL1/MAP3K12/MEAK7/ARRB2/SOD1/NONO/NTRK2/POU4F1/NR4A2/BTG2/TBC1D24/TERT/FOXQ1/CDK5/CX3CR1/SEMA3E/BCL2L1/CEBPB/LIG4/HRAS/BDNF/JUN/F2R/CSF1/PRKN/CLN3/FZD9/SYNGAP1/NTRK1/GPRASP3/NAIP/IKBKG/NAIP/NEFL/NAIP/GPI 74
GO:0065004 protein-DNA complex assembly 79/3662 218/15509 1.67222e-05 0.000139307 8.37766e-05 MED24/MED17/RAD51/MED29/RNF4/SIRT6/ATRX/ESR1/SUPT16H/MED15/SMARCB1/PSMC6/TAF1C/CHRAC1/MED25/MACROH2A1/DR1/HELLS/CENPK/H1-3/H2BC11/THRA/HP1BP3/MED6/ANP32B/TAF8/CENPE/RB1/CENPC/BDP1/SSRP1/SMARCA5/H2BC5/CHAF1B/PADI4/TAF6L/H3-3A/MED30/GTF2A1/CENPN/CHAF1A/H1-4/CENPX/MED16/TAF7/NPM1/H2BC21/BRF1/H1-2/CENPP/H2AX/H1-0/HMGB1/H2BC26/TAF13/BRD2/DAXX/DAXX/DNAJC9/BRD2/DAXX/DAXX/BRD2/DAXX/H2BC15/BRD2/BRD2/H4C15/H4C14/H4C12/H2BC6/H3C6/SMARCB1/H4C5/H4C4/H2BC7/H3C10/PADI4/H3C2 79
GO:0001660 fever generation 13/3662 18/15509 1.74776e-05 0.000144821 8.70926e-05 IL1A/IL1B/EDNRB/TNFRSF11A/TRPV1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 13
GO:0002524 hypersensitivity 13/3662 18/15509 1.74776e-05 0.000144821 8.70926e-05 BTK/FCGR2B/GATA3/C3/CCR7/ZP3/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 13
GO:0030656 regulation of vitamin metabolic process 13/3662 18/15509 1.74776e-05 0.000144821 8.70926e-05 SNAI2/CYP27B1/IFNG/GFI1/AKR1C3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 13
GO:0046851 negative regulation of bone remodeling 13/3662 18/15509 1.74776e-05 0.000144821 8.70926e-05 CD38/P2RX7/CSK/SFRP1/HAMP/CALCA/TNFAIP3/IAPP/IL6/TNFRSF11B/INPP5D/GPR137/INPP5D 13
GO:0198738 cell-cell signaling by wnt 135/3662 415/15509 1.76359e-05 0.000145937 8.77642e-05 WNT16/ITGA3/PAF1/SNAI2/PTPRU/CDH3/FGFR2/RHOA/VPS35/CSNK2A2/CDC42/MARK2/FBXW11/GPC4/GSK3B/ABL1/GSKIP/CHD8/FERMT1/AXIN1/TSC2/SFRP1/TLE5/CCNE1/TGFB1/GSK3A/HBP1/SFRP4/SPIN1/DVL1/GATA3/FBXW4/DKK1/RNF43/WNT3/CCND1/FOLR1/MDK/WNT5B/FZD10/MAPK14/PPP2CA/ARL6/NPHP3/AMOTL2/KPNA1/WNT5A/IGFBP2/SDC1/BCL9/HDAC1/TNFAIP3/FOXO3/PKD2/SFRP5/EGR1/RECK/PFDN5/LRP1/SOX4/BMP2/PIN1/APOE/PRKAA1/LRP4/APC/MDFIC/EDNRB/PPM1B/FGF2/EGF/SKIC8/CSNK1D/APP/CELSR2/RBMS3/TPBG/EGFR/NOTCH1/TCF7L2/FOXO1/HHEX/NR4A2/GNAQ/WIF1/SKI/DVL3/WNT4/VANGL2/DISC1/FRZB/PYGO2/TERT/SHH/VCP/AMER2/NDRG2/BRD7/BTRC/NXN/RBPJ/ZEB2/CTNND2/CDH2/RARG/RNF213/FZD4/DDIT3/FOXL1/CTNNBIP1/NKX2-5/NOG/ZNF703/NOTUM/PRKN/ROR1/BCL9L/RNF220/MAGI2/WNT7B/FZD9/SRC/GRK6/NRARP/GRK5/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CD24/WNT3/WNT3/LRP6/PTEN 135
GO:0051493 regulation of cytoskeleton organization 151/3662 473/15509 1.7695e-05 0.000146072 8.78453e-05 SCIN/PAFAH1B1/SPAST/PARP3/EPHA3/CYFIP2/RNF4/RHOA/NAV3/ROCK1/SPTB/CDC42/WDR1/MARK2/ARHGEF10L/ADD2/SPAG5/ACTN2/GSK3B/CHMP5/ADD1/TPX2/P2RX7/PXN/ABL1/HCK/CHMP4B/COTL1/NUBP1/PYCARD/TJP1/SFRP1/ARHGEF10/SYDE1/MTPN/MET/TGFBR1/CXCL12/CSF3/RANGRF/MDK/ARPC3/FZD10/NEDD9/PDGFRB/DBN1/CEP70/KAT2B/IL1A/CAPZA1/STMN1/TEK/PTK2B/LRP1/EML2/DSTN/ID1/CCR7/CDC42EP1/RAC2/ARPC1B/CHMP1A/PPFIA1/PRKAA1/WASF3/KATNBL1/PSRC1/NOTCH2/PDGFRA/APC/BORA/DBNL/CCL21/ATAT1/NUMA1/RDX/ABI2/SLAIN1/BBS4/ARHGDIA/TBCD/SMAD4/ABL2/RHOB/SLIT2/EPHA5/PIK3R1/IQGAP2/ARHGAP18/C9orf72/GSN/CDC42EP2/BICD1/PLEKHH2/SKA1/DMTN/ARHGAP35/SPTBN4/ALOX15/WNT4/ARPC5/CAPN2/ANKRD23/CDC42EP3/SPTA1/PRKCD/MAP9/ARFIP1/RICTOR/CDK5/SKA3/TTC8/MAPRE2/RHOH/PTK2/SEMA3E/S1PR1/PRKCE/MAP6/CCL11/SPTBN2/HRAS/CHMP6/CDK5R1/FLII/GRB2/PAK2/MAPK15/NPM1/CSF1R/CIB1/INPP5J/CDK10/GAS2L1/PRKN/DRG1/NF2/CLN3/CD47/GMFB/SPTAN1/MTOR/IQANK1/TMSB4X/PDXP/ARPC1A/TWF2/SHANK3/BRK1/ITGB3/TJP1 151
GO:0045931 positive regulation of mitotic cell cycle 45/3662 107/15509 1.77003e-05 0.000146072 8.78453e-05 CDC27/KMT2E/PAFAH1B1/ASNS/ANAPC5/CDC6/ABL1/CDC7/APEX1/CDC25B/RAB11A/RPS6KB1/CCND1/FBXO5/SMOC2/CCND3/HES1/TTL/HSPA2/CCNB1/RDX/BRCA2/RB1/CUL4A/CYP1A1/APP/DTL/EGFR/PRKCA/ADAMTS1/LSM11/CUL4B/DBF4B/TAL1/TERT/RRM1/CDK1/RRM2/STAT5B/RCC2/PTPN11/PLCB1/CDK10/PBX1/TFDP1 45
GO:0010952 positive regulation of peptidase activity 67/3662 178/15509 1.77316e-05 0.000146072 8.78453e-05 BAD/CASP10/FAS/BAK1/GRN/CYFIP2/NGFR/RHOA/PSME4/PICALM/FBLN1/BAX/PSME1/MEFV/PYCARD/PDCD5/NOD1/CASP2/PERP/FN1/HSPE1/FASLG/TNFSF10/SEMG1/ADRM1/PSME3/AKIRIN2/TANK/ANP32B/MTCH1/BCL2L10/PMAIP1/APP/CCN1/ARL6IP5/GSN/BCL2L11/NODAL/GPER1/SYK/VCP/FADD/LGALS9/PRELID1/EFNA1/ANTXR1/EIF2AK3/GRIN1/SVBP/F2R/CARD9/HMGB1/DAPK1/MAP3K5/MBP/CR1/TNF/PSENEN/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/PDCD6 67
GO:0001796 regulation of type IIa hypersensitivity 9/3662 10/15509 1.78407e-05 0.000146072 8.78453e-05 FCGR2B/C3/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 9
GO:0002419 T cell mediated cytotoxicity directed against tumor cell target 9/3662 10/15509 1.78407e-05 0.000146072 8.78453e-05 MR1/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A 9
GO:0002481 antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent 9/3662 10/15509 1.78407e-05 0.000146072 8.78453e-05 TAP2/TAP2/TAP2/TAP2/TAP2/TAP2/TAP2/TAP2/B2M 9
GO:0002892 regulation of type II hypersensitivity 9/3662 10/15509 1.78407e-05 0.000146072 8.78453e-05 FCGR2B/C3/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 9
GO:1904997 regulation of leukocyte adhesion to arterial endothelial cell 9/3662 10/15509 1.78407e-05 0.000146072 8.78453e-05 ZDHHC21/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 9
GO:1902850 microtubule cytoskeleton organization involved in mitosis 56/3662 142/15509 1.79785e-05 0.000147007 8.84072e-05 PAFAH1B1/SPAST/PARP3/EML1/RHOA/SMC1A/FBXW11/NDE1/NDC80/PIBF1/CHMP5/ZW10/TPX2/NSFL1C/BIRC5/NUDC/KIF4A/MYBL2/CHMP4B/RAB11A/ARHGEF10/BCCIP/SMC3/CDC20/STMN1/PTPA/SBDS/CHMP1A/CCNB1/PSRC1/CDCA8/BORA/SPRY2/NUMA1/NUSAP1/KIF23/CENPE/PLK2/ITGB1/SPC25/GJA1/PCNT/MAP9/VCP/GOLGA2/KAT5/CHMP6/AURKB/SETD2/CHEK2/DRG1/KIFC1/LSM14A/NDE1/TBCE/SPICE1 56
GO:0008608 attachment of spindle microtubules to kinetochore 22/3662 40/15509 1.83064e-05 0.000149294 8.97826e-05 SIRT2/CDC42/SPAG5/NDC80/SEH1L/BIRC5/KAT2B/TEX14/BECN1/CCNB1/CDCA8/APC/KNL1/CENPE/RB1/KIF2C/CENPC/BOD1/SPC25/KAT5/AURKB/RCC2 22
GO:0050999 regulation of nitric-oxide synthase activity 22/3662 40/15509 1.83064e-05 0.000149294 8.97826e-05 ATP2B4/FCER2/NOD1/IL1A/PTK2B/IL1B/APOE/EGFR/DDAH1/CALM3/TERT/LEP/ZDHHC21/CNR2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 22
GO:0061564 axon development 147/3662 459/15509 1.89562e-05 0.000154389 9.28471e-05 IFRD1/PAFAH1B1/CNTN1/SPAST/GRN/CDH1/EPHA3/LAMA3/NGFR/NTN1/FGFR2/EPHA8/MARK2/PICALM/GLI2/NOTCH3/ACTB/PLXNA2/EPHA6/GSK3B/RAB10/MMP2/DPYSL2/HSP90AB1/ABL1/ADNP/BMP7/LAMA1/SCN1B/PTN/DVL1/GATA3/CXCL12/UNC5B/PPP3CB/WNT3/CNTNAP1/EFNB3/ZPR1/FOLR1/DBN1/WNT5A/TTL/ITGA4/FN1/MTR/STMN1/NRP2/SPP1/EGR2/USP9X/FLRT3/BCL11B/RAC2/CHN1/APOE/LAMA5/EPHB2/TSPAN2/NOTCH2/NGF/LRP4/DBNL/NKX2-1/STXBP1/KIAA0319/TUBB2B/IGF1R/RNF165/SMAD4/APP/EPHA2/CRABP2/SLIT2/EPHA5/TNFRSF21/C9orf72/NTRK2/NOTCH1/PARD3/NCAM1/ITGB1/POU4F2/POU4F1/NR4A2/UCHL1/DPYSL5/B4GALT5/ISL2/ARHGAP35/SPTBN4/BRSK1/TBC1D24/DISC1/SLC25A46/CASP3/SHH/ADCY1/CDK5/TTC8/RHOH/SEMA4C/EFNA1/PTK2/SEMA3E/CDH2/KIF5B/NPTX1/LPAR3/MAP6/LAMB2/BSG/DAG1/CNP/BRSK2/BDNF/CDK5R1/JUN/SVBP/CDH4/PTPN11/PAK2/ADGRB1/RGMA/CSF1R/EPHB3/NOG/CNTN2/SLIT3/POU3F2/DCC/SYNGAP1/SIPA1L1/MBP/NTRK1/GDI1/TCTN1/TMEFF1/EFNA4/TWF2/TUBB3/EPHB6/NEFL/WNT3/WNT3/TBCE/PTEN 147
GO:0051168 nuclear export 55/3662 139/15509 1.90067e-05 0.000154598 9.29722e-05 UPF1/RANBP3/THOC3/SP100/SMG6/PRKACA/SIRT6/GSK3B/XPO1/ALKBH5/RANGAP1/PABPN1/UBE2I/TGFB1/CASC3/HSPA9/PARK7/NRDE2/EGR2/CSE1L/NUP153/NUP85/IL1B/NXT1/XPO4/HNRNPA1/LTV1/NCBP1/ANP32B/EIF4A3/POLR2D/TCF7L2/BAG3/HHEX/RANBP2/NXF1/THOC7/RANBP3L/CDK5/NEMF/AHCYL1/DDX19A/NMD3/CALR/PTPN11/NPM1/SETD2/XPOT/SDAD1/SMG5/SARNP/EIF6/RBM15B/RBM8A/PRKACA 55
GO:0014823 response to activity 32/3662 68/15509 1.93384e-05 0.000156884 9.43474e-05 CRY1/CYBA/OXCT1/MMP2/ANGPT2/PPARD/CRY2/CAT/CXCR4/PRKAA1/IL6/IL10/ALAD/ZEB1/BMP6/FNDC5/SELENON/CDK1/FOS/LEP/ADIPOQ/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ADSL/MTFP1/ITGB3 32
GO:0034103 regulation of tissue remodeling 32/3662 68/15509 1.93384e-05 0.000156884 9.43474e-05 CD38/FLT4/ROCK1/P2RX7/CSK/SFRP1/TGFB1/HAMP/MDK/CALCA/IL12B/LEPR/TNFAIP3/SPP1/IAPP/IL6/IL21/DEF8/TNFRSF11A/IL18/PRKCA/RUNX1/TNFRSF11B/SYK/INPP5D/S1PR1/GPR137/LEP/CSF1R/SRC/ITGB3/INPP5D 32
GO:0007599 hemostasis 79/3662 219/15509 2.01835e-05 0.000163526 9.83418e-05 SLC4A1/CD9/F7/LMAN1/ACTB/FBLN1/CD59/APOH/PDGFB/MYH9/CTSG/PROCR/CD40/GATA1/CD40LG/DGKH/PLAT/GPI/TFPI2/PIK3CG/HSPB1/SERPINE1/HGFAC/VWF/SH2B3/MAPK14/FN1/MPL/SERPINC1/GNA13/F13A1/APOE/AP3B1/EPHB2/PDGFRA/CD36/SERPINE2/IL6/STXBP1/TLR4/THBS1/ADAMTS18/GNA12/AK3/MERTK/DGKE/PRKCA/GNAQ/DMTN/ADAMTS13/ZNF385A/PF4/PRKCD/ANXA5/F2RL2/SHH/NOS3/SYK/FUNDC2/HPS6/PRDX2/C1GALT1C1/FGG/FGA/JMJD1C/SELP/F2/F2R/ANXA2/ADRA2C/PLSCR1/BLOC1S3/PPIA/SRC/F5/HBB/ITGB3/ADAMTS13/GPI 79
GO:0045779 negative regulation of bone resorption 12/3662 16/15509 2.02774e-05 0.000163645 9.84134e-05 CD38/P2RX7/CSK/HAMP/CALCA/TNFAIP3/IAPP/IL6/TNFRSF11B/INPP5D/GPR137/INPP5D 12
GO:0051988 regulation of attachment of spindle microtubules to kinetochore 12/3662 16/15509 2.02774e-05 0.000163645 9.84134e-05 SIRT2/CDC42/SPAG5/BIRC5/KAT2B/BECN1/CCNB1/CDCA8/APC/KAT5/AURKB/RCC2 12
GO:2000347 positive regulation of hepatocyte proliferation 12/3662 16/15509 2.02774e-05 0.000163645 9.84134e-05 XBP1/PTN/MDK/TNFAIP3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 12
GO:0043434 response to peptide hormone 123/3662 373/15509 2.04375e-05 0.000164723 9.90615e-05 CRY1/CPS1/CYBA/KCNQ1/F7/PKM/ROCK1/ACTN2/OPRK1/GSK3B/RAB10/PXN/NUDC/CDC6/XBP1/RANGAP1/APEX1/PCK2/BMP7/TSC2/CSK/PLAT/SLC39A14/JAK3/GSK3A/CXCL12/RPS6KB1/AREG/MAPK14/CCND3/KAT2B/NCL/STAT1/SRSF4/SLC2A1/ARG1/NR4A3/EIF2B2/CRHR1/EGR1/CRY2/CAT/TNFSF10/INHBA/EGR2/NR4A1/NCOA5/IL1B/MAX/STAT5A/CDO1/GDF15/ASS1/SESN2/PRKAA1/LPIN3/MEN1/APC/EDNRB/IL10/SORL1/KHK/CYP1B1/RB1/IGF1R/MEAK7/TNFRSF11A/RAB13/PKLR/PARP1/CCNA2/PIK3R1/OGT/EIF4EBP2/SESN3/SOGA1/FOXO1/POU4F2/NR4A2/APPL1/ADIPOR1/BTG2/SHC1/JAK1/SCNN1D/INHBB/PRKCD/GPER1/CYBB/ZNF592/SLC27A4/AHCYL1/PTK2/FOS/SLC25A33/BSG/RELA/ESRRA/DAG1/STAT5B/LEP/PTPN2/LPL/GRB2/ERFE/PTPN11/OXTR/ADIPOQ/PLCB1/FOXO4/SOCS1/ZFP36L1/TRPV1/SRC/MTOR/EIF6/PRKDC/ITGB3/GH1/PKLR/PIP4K2B/NEFL/LRP6 123
GO:0033273 response to vitamin 35/3662 77/15509 2.05605e-05 0.000165498 9.95279e-05 SNAI2/CASR/F7/BMP7/SFRP1/HAMP/CCND1/FOLR1/CYP27B1/VDR/PPARD/IL1A/ARG1/SPP1/DNMT3A/TRIM25/CAT/TRIM24/RUNX2/BECN1/ALDH1A2/EPO/RARA/IGF1R/CYP1A1/ALAD/STC1/AQP3/MN1/MGMT/LEP/TYMS/KANK2/F5/LOC102724560 35
GO:0032770 positive regulation of monooxygenase activity 20/3662 35/15509 2.06207e-05 0.000165553 9.95606e-05 CDH3/FCER2/NOD1/CYP27B1/VDR/IFNG/PARK7/PTK2B/IL1B/APOE/CALM3/TERT/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 20
GO:0045191 regulation of isotype switching 20/3662 35/15509 2.06207e-05 0.000165553 9.95606e-05 PARP3/FOXP3/TBX21/MLH1/PTPRC/MSH2/CD40/IL27RA/TGFB1/EXOSC3/NSD2/IL4/BCL6/SHLD2/NDFIP1/IL10/SLC15A4/TNFSF13/CD28/PTPRC 20
GO:0016045 detection of bacterium 18/3662 30/15509 2.14886e-05 0.000172075 0.000103483 NOD1/NOD2/HLA-B/HLA-A/HLA-A/HLA-B/HLA-A/HLA-A/HLA-B/HLA-A/HLA-B/HLA-A/HLA-A/HLA-B/HLA-A/NAIP/NAIP/NAIP 18
GO:1903798 regulation of miRNA maturation 18/3662 30/15509 2.14886e-05 0.000172075 0.000103483 ZMPSTE24/ESR1/TGFB1/DDX5/MYCN/IL6/TARBP2/EGFR/TERT/TRUB1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 18
GO:0000070 mitotic sister chromatid segregation 64/3662 169/15509 2.16925e-05 0.000172786 0.00010391 CDC27/BAZ1B/ARID1B/SMC1A/ACTB/SPAG5/NDC80/PIBF1/ATRX/SEH1L/CHMP5/ZW10/ANAPC5/BIRC5/NUDC/KIF4A/CDC6/BCL7C/SMARCB1/CHMP4B/RAB11A/SMC3/SMARCD2/BCL7A/FBXO5/MACROH2A1/SMC4/KAT2B/CDC20/NSL1/ARID1A/SLF2/TEX14/NAA50/PDS5A/CENPK/BECN1/MAU2/CHMP1A/CCNB1/PSRC1/CDCA8/APC/NUMA1/NUSAP1/KIF23/CENPE/RB1/KIF2C/CENPC/BOD1/NCAPG2/SPC25/SMARCA5/BRD7/BUB1/KAT5/ZWILCH/CHMP6/AURKB/KMT5A/ARID2/KIFC1/SMARCB1 64
GO:0019216 regulation of lipid metabolic process 104/3662 306/15509 2.17012e-05 0.000172786 0.00010391 MBTPS2/SNAI2/CD74/H6PD/MTMR1/DDX20/PLPP1/PDK3/FGFR3/CDC42/EPHA8/ACADVL/SIRT6/PIBF1/ZMPSTE24/APOB/PIK3IP1/PDGFB/EEF1A2/FLT1/ASAH1/TGFB1/PIK3CG/EDF1/CD81/CYP27B1/IFNG/PPARD/PDE8B/MACROH2A1/PDGFRB/IL1A/ID2/NR4A3/TEK/EGR1/PTK2B/EPHX2/FLT3/ORMDL2/RAB38/ACSL3/IL1B/C3/BMP2/THRA/CCR7/NR1D1/ATG14/BCL11B/APOE/PRKAA1/PDGFRA/CCL21/SORL1/FGF2/IGF1R/BBS4/ARMC5/ASXL3/SOD1/CCN1/ERLIN2/BMP6/KIT/LDLRAP1/ADIPOR1/WNT4/GFI1/CAPN2/ATP1A1/FABP1/PRKCD/GPER1/NOD2/ABCA3/PTK2/ALK/PRKCE/ORMDL3/CCL19/KAT5/ARV1/STAT5B/RNF213/LEP/CD19/ERFE/F2/ADIPOQ/KLHL25/AKR1C3/SRC/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/PIP4K2B 104
GO:0009820 alkaloid metabolic process 10/3662 12/15509 2.17614e-05 0.000172786 0.00010391 CYP2D6/CYP3A5/CYP1A2/CYP3A4/NNMT/CYP2D6/CYP2D6/CYP2D6/CYP2D6/CYP2D6 10
GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 10/3662 12/15509 2.17614e-05 0.000172786 0.00010391 FOXP3/IFNG/IL2RG/LGALS9/KLHL25/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 10
GO:0032831 positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 10/3662 12/15509 2.17614e-05 0.000172786 0.00010391 FOXP3/IFNG/IL2RG/LGALS9/KLHL25/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 10
GO:0060664 epithelial cell proliferation involved in salivary gland morphogenesis 10/3662 12/15509 2.17614e-05 0.000172786 0.00010391 FGFR2/SHH/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 10
GO:0051898 negative regulation of protein kinase B signaling 23/3662 43/15509 2.17725e-05 0.000172786 0.00010391 HYAL2/TSC2/SH2B3/PPP2CA/SFRP5/ARRB2/EPHA2/GPER1/OTUD3/DAG1/DDIT3/CIB1/MAGI2/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/PDCD6/HLA-G/PTEN 23
GO:0002036 regulation of L-glutamate import across plasma membrane 11/3662 14/15509 2.20957e-05 0.000174903 0.000105183 PER2/ARL6IP5/ITGB1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 11
GO:0046645 positive regulation of gamma-delta T cell activation 11/3662 14/15509 2.20957e-05 0.000174903 0.000105183 PTPRC/LILRB1/SOX4/SYK/NOD2/STAT5B/PTPRC/LILRB1/LILRB1/LILRB1/LILRB1 11
GO:1901987 regulation of cell cycle phase transition 122/3662 370/15509 2.21449e-05 0.000175069 0.000105283 CDC27/KMT2E/DBF4/PAF1/CRY1/FHL1/USP28/ARID1B/RAD51/ATP2B4/SIRT2/ACTB/NDC80/ZW10/ANAPC5/BIRC5/PSME1/CDC6/MSH2/CDC7/BCL7C/SMARCB1/APEX1/CDC25B/RBBP8/RAB11A/NBN/ERCC2/DOT1L/CASP2/EZH2/SMARCD2/CCL2/CCND1/BCL7A/FBXO5/MAPK14/CCND3/CCNG1/RAD50/PPP2CA/MACROH2A1/ID2/CDC20/ARID1A/PKD2/TEX14/INHBA/CDKN1A/HSPA2/PSME3/MEN1/CCNB1/CCNH/CDCA8/APC/RDX/CENPE/NABP2/BRCA2/RB1/CUL4A/CYP1A1/APP/DTL/DYRK3/INTS3/CTDSP1/PLK2/EGFR/SPC25/ZFP36L2/ADAMTS1/XPC/EME1/LSM11/APPL1/CUL4B/PRMT2/BRSK1/MRNIP/DBF4B/RPL26/ERCC3/TERT/BRD7/WEE1/RRM1/RFWD3/MN1/BUB1/AVEN/CDK1/TRIAP1/RHNO1/RRM2/NABP1/ZWILCH/CTDSP2/AURKB/RCC2/PTPN11/MAPK15/NPM1/CACNB4/PLCB1/CEP63/CHEK2/FOXO4/CDK10/MUC1/PBX1/ZFP36L1/H2AX/ARID2/KANK2/TFDP1/GIGYF2/PRKDC/SMARCB1/PAGR1/PTEN 122
GO:0043401 steroid hormone mediated signaling pathway 52/3662 130/15509 2.23141e-05 0.000176182 0.000105953 KDM1A/CRY1/RNF14/UFL1/PLPP1/RHOA/TP63/PIAS2/PGR/ESR1/RBFOX2/BMP7/SFRP1/ZMIZ1/DDX5/PPARD/KDM3A/PARK7/HDAC1/PADI2/ARID1A/NR4A3/CRY2/PKN1/CNOT1/NR1D1/YWHAH/WBP2/CARM1/PARP1/CNOT9/POU4F2/NODAL/PRMT2/HEYL/GPER1/TRIM68/PAQR8/TADA3/CYP7B1/ESRRA/TAF7/CALR/SRC/KANK2/RXRB/DAXX/DAXX/DAXX/DAXX/DAXX/PAGR1 52
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 89/3662 254/15509 2.28663e-05 0.000180312 0.000108437 ITGA3/HFE/HSPA5/ARID4B/HIPK2/ITGA8/LRP2/FKBP1A/GLG1/HSP90AB1/ABL1/BMP7/FERMT1/SMAD7/RBBP7/AXIN1/SFRP1/TGFB1/SFRP4/TGFBR1/ENG/BMPR1A/DKK1/FOLR1/ZNF451/WNT5A/HES1/HDAC1/SFRP5/INHBA/LRP1/BMP2/PIN1/KDR/TWSG1/CDKN1C/GDF15/MEN1/NOTCH2/SPRY2/NKX2-1/CCN3/KIAA0319/NUMA1/SORL1/THBS1/SMAD6/TET1/FBN2/TOB1/RNF165/SMAD4/CCN1/PARP1/OGT/NOTCH1/ZEB1/CRIM1/BMP6/NODAL/SKI/RBBP4/INHBB/TGFBR2/SAP30/GDF9/ELAPOR2/SHH/HTRA1/RBPJ/ZEB2/SMAD2/EID2/RGMA/NOG/ZNF703/BCL9L/TMPRSS6/MAGI2/TRIM33/SLC2A10/SPRED2/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CDKN1C/CRIM1 89
GO:0051962 positive regulation of nervous system development 93/3662 268/15509 2.33826e-05 0.000184149 0.000110744 KDM1A/PAFAH1B1/UFL1/TNFRSF1B/NTN1/PLXNA2/TP73/XRCC5/LRP2/ADNP/TGFB1/PTN/CXCL12/WNT3/MDK/IFNG/DBN1/HES1/FN1/ID2/HDAC1/CXCR4/EGR2/OBSL1/IL1B/NKX2-2/BMP2/FLRT3/LIF/EPHB2/KRAS/NGF/SERPINE2/IL6/DBNL/ACTR2/FGF2/CLSTN3/ST8SIA2/CRABP2/SLIT2/TPBG/NTRK2/NOTCH1/ITGB1/VEGFC/POU4F2/KIT/FAIM/TBC1D24/DISC1/SHH/GPER1/CX3CR1/RGS14/LPAR3/MAP6/DAG1/LIG4/BDNF/CDH4/OXTR/PLAG1/ADGRB1/EPHB3/SS18L1/THBS2/IL1RAP/MME/NTRK1/MTOR/GPRASP3/TGM2/GDI1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/TWF2/SHANK3/CUX1/NEFL/WNT3/WNT3 93
GO:0006470 protein dephosphorylation 84/3662 237/15509 2.38063e-05 0.000187248 0.000112608 PTBP1/PPP5C/PHLPP2/PTPRU/ROCK1/FBXW11/PTPRC/DUSP12/GSK3B/PPP1R15A/FKBP1A/HSP90AB1/PPP6R2/CDKN3/CDC25B/PPP1R16B/EYA1/TGFB1/CD33/PPP3CB/PTPMT1/PPM1H/PTP4A1/PPP2R5D/PPP2CA/PDGFRB/PTPA/PPP6C/MASTL/CRY2/PIN1/STYXL1/PTPN22/PPM1B/DUSP5/MTMR6/ENSA/DUSP10/ACP1/CALM2/CTDSP1/BOD1/GNA12/PPP4C/PPP2R5E/SPPL3/DUSP2/PPP1R15B/CALM3/SSU72/PRKCD/DUSP7/NSMF/BTRC/PPP2R3B/PPM1D/PDP2/CTDSP2/PTPN2/ANKLE2/PTPN11/PPP1R2/PTP4A3/MAGI2/PPIA/MTOR/CSNK2B/TNF/PPP1R11/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PDXP/PGAM5/PTPRC/PTEN 84
GO:0071559 response to transforming growth factor beta 86/3662 244/15509 2.43084e-05 0.000190756 0.000114718 ITGA3/RUNX3/HSPA5/ARID4B/HIPK2/SPI1/FGFR2/ROCK1/HYAL2/ITGA8/FKBP1A/PXN/GLG1/HSP90AB1/ABL1/FERMT1/SMAD7/RBBP7/AXIN1/SFRP1/PDCD5/TGFB1/TGFBR1/ENG/BMPR1A/ZMIZ1/LPXN/FOLR1/ZNF451/IL4/SMAD5/WNT5A/STK16/HDAC1/ARG1/FMOD/USP9X/BMP2/ID1/PIN1/TWSG1/CDKN1C/GDF15/MEN1/SPRY2/NKX2-1/THBS1/SMAD6/TET1/FBN2/IGF1R/FURIN/ARRB2/SMAD4/PARP1/OGT/ZEB1/ZFP36L2/NODAL/APPL1/SKI/RBBP4/WNT4/TGFBR2/SAP30/GDF9/HTRA1/CX3CR1/ADAM9/PTK2/ZEB2/LIMS1/FOS/PDE3A/SMAD2/EID2/JUN/PAK2/ZNF703/ZFP36L1/BCL9L/SRC/TRIM33/SLC2A10/SPRED2/CDKN1C 86
GO:0048144 fibroblast proliferation 44/3662 105/15509 2.43139e-05 0.000190756 0.000114718 IGF1/CD74/NGFR/DAZAP1/FOSL2/SIRT6/ZMPSTE24/BAX/ESR1/CDC6/ABL1/PDGFB/SFRP1/MED25/ZMIZ1/PDGFRB/WNT5A/FN1/PRDX1/CDKN1A/LIF/CCNB1/PDGFRA/CCNA2/PDGFC/EGFR/SKI/TP53INP1/FTH1/CDK1/CKS1B/LIG4/HRAS/JUN/C1QL4/WNT7B/LTA/LTA/LTA/LTA/LTA/BRK1/ITGB3/MIF 44
GO:0032970 regulation of actin filament-based process 119/3662 360/15509 2.44974e-05 0.000191953 0.000115437 SCIN/EPHA3/CYFIP2/PKP2/RHOA/ROCK1/SPTB/CDC42/WDR1/ARHGEF10L/ADD2/ACTN2/ADD1/PXN/DSP/ABL1/MYH9/HCK/COTL1/PYCARD/TJP1/SFRP1/ARHGEF10/MTPN/MET/TGFBR1/CXCL12/ACTA2/CSF3/RANGRF/MDK/ARPC3/FZD10/NEDD9/PDE4D/PDGFRB/DBN1/IL1A/CAPZA1/STMN1/TNNT2/TEK/PTK2B/LRP1/KCNJ2/DSTN/ID1/CCR7/CDC42EP1/RAC2/ARPC1B/PPFIA1/WASF3/NOTCH2/PDGFRA/DBNL/CCL21/RDX/ABI2/BBS4/ARHGDIA/SMAD4/ABL2/RHOB/SLIT2/EPHA5/ANK2/PIK3R1/IQGAP2/ARHGAP18/C9orf72/GSN/CDC42EP2/PLEKHH2/DMTN/STC1/ARHGAP35/SPTBN4/ALOX15/WNT4/ARPC5/ANKRD23/CDC42EP3/SPTA1/PRKCD/ARFIP1/RICTOR/CDK5/TTC8/RHOH/SEMA3E/S1PR1/PRKCE/CCL11/SPTBN2/ATP2A2/HRAS/CDK5R1/FLII/GRB2/PAK2/CSF1R/PDE4B/CDK10/PRKN/NF2/CD47/GMFB/SPTAN1/MTOR/IQANK1/TMSB4X/PDXP/ARPC1A/TWF2/SHANK3/BRK1/ITGB3/TJP1 119
GO:0046777 protein autophosphorylation 76/3662 210/15509 2.52594e-05 0.000197674 0.000118878 MAP3K9/BTK/MVP/CLK1/FLT4/EIF2AK2/FGFR2/FGFR3/EPHA8/PRKACA/MARK2/FGFR1/MKNK1/PTPRC/STK17B/GSK3B/MAPKAPK5/ABL1/MKNK2/PDGFB/RASSF2/HCK/FLT1/CSK/NBN/PRKD2/ENG/RAD50/PDGFRB/ZAP70/STK16/PASK/TEK/PTK2B/FLT3/TRIM24/KDR/PDGFRA/MAP3K12/IGF1R/ULK3/MAP3K21/CALM2/PDGFC/EGFR/NTRK2/VEGFC/KIT/CALM3/MAPKAPK2/CDK5/SYK/CDK12/PTK2/ALK/EIF2AK3/ATG13/JUN/FAM20C/ERN1/AURKB/PAK2/MAPK15/ADIPOQ/CSF1R/EPHB3/CHEK2/IRAK1/DAPK1/SRC/PIM3/NTRK1/MTOR/GRK5/PTPRC/PRKACA 76
GO:0045124 regulation of bone resorption 21/3662 38/15509 2.57166e-05 0.000200998 0.000120877 CD38/P2RX7/CSK/HAMP/CALCA/TNFAIP3/SPP1/IAPP/IL6/DEF8/TNFRSF11A/PRKCA/TNFRSF11B/SYK/INPP5D/S1PR1/GPR137/CSF1R/SRC/ITGB3/INPP5D 21
GO:1900221 regulation of amyloid-beta clearance 15/3662 23/15509 2.60366e-05 0.000203243 0.000122227 ROCK1/IFNG/IL4/HDAC1/CLU/LRP1/APOE/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:0140694 non-membrane-bounded organelle assembly 111/3662 332/15509 2.62545e-05 0.000204686 0.000123094 PUM2/RNF4/RHOA/WDR1/SMC1A/MLH1/SPAG5/ACTN2/XRCC5/NDC80/PIBF1/CHMP5/TPX2/RPL6/BIRC5/KIF4A/CIRBP/MYBL2/HCK/CHMP4B/RAB11A/CEP152/SQLE/ARHGEF10/BCCIP/SMC3/C1QBP/DDX6/NOP2/FBXO5/BRIX1/IL5/PDGFRB/KAT2B/CDC20/TNNT2/CENPK/OBSL1/CNOT1/SBDS/STYXL1/CHMP1A/PRKAA1/ERAL1/MYH11/CDCA8/PDGFRA/LCP1/DBNL/NUMA1/KIF23/HAUS2/CENPE/CSNK1D/SMAD4/GRB7/UBAP2L/CENPC/PLK2/ABT1/MSN/C9orf72/GSN/ITGB1/DHX37/BICD1/ANKRD23/MAP9/CSF2/RPL10L/ZFYVE1/CENPN/MAPRE2/GOLGA2/CENPX/RNF213/CEP135/CHMP6/FLII/PLEC/AURKB/MAPK15/NPM1/CEP63/NKX2-5/CHEK2/DRG1/YTHDF3/RRP7A/TUBB/SRC/RPL23A/CCDC69/TNF/TNF/HAUS3/TNF/TNF/TNF/TNF/TNF/TNF/KIFC1/PISD/PWP2/EIF6/PRKDC/LSM14A/BOP1/MYH11/SPICE1 111
GO:0008585 female gonad development 41/3662 96/15509 2.66115e-05 0.000207208 0.000124611 HSPA5/MSH4/PGR/BAX/MMP2/ESR1/PCYT1B/SFRP1/CASP2/FOXO3/EIF2B2/INHBA/KDR/PDGFRA/CYP19A1/BRCA2/ARRB2/SMAD4/SOD1/SLIT2/GAS2/ARID5B/ADAMTS1/MMP14/KIT/WNT4/INHBB/CASP3/GDF9/NOS3/ZFPM2/BCL2L1/CEBPB/STAT5B/LEP/FZD4/A2M/SLIT3/ZP3/SRC/FANCG 41
GO:0061180 mammary gland epithelium development 31/3662 66/15509 2.72142e-05 0.000211635 0.000127274 NTN1/FGFR2/PGR/BAX/ESR1/HOXA5/GATA3/WNT3/AREG/CCND1/VDR/WNT5A/ID2/KDM5B/IRF6/FGF2/BRCA2/EPHA2/WNT4/PYGO2/BTRC/MGMT/CCL11/CEBPB/CSF1R/ZNF703/CSF1/WNT7B/SRC/WNT3/WNT3 31
GO:0051341 regulation of oxidoreductase activity 40/3662 93/15509 2.72566e-05 0.0002117 0.000127313 SLC4A1/CYBA/ATP2B4/CDH3/ABL1/FCER2/NOD1/CYP27B1/VDR/IFNG/IL1A/PARK7/PTK2B/IL1B/ECSIT/APOE/FDX1/COX17/ABL2/EGFR/DDAH1/CALM3/GFI1/TERT/FXN/NOD2/PDP2/LEP/ZDHHC21/PRKN/CNR2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HP 40
GO:1904377 positive regulation of protein localization to cell periphery 32/3662 69/15509 2.79538e-05 0.000216843 0.000130406 ITGA3/EPHA3/ATP2B4/RANGRF/IFNG/LRP1/RAB38/ACSL3/EPHB2/NUMA1/EPHA2/STAC/PIK3R1/EGFR/ITGB1/RER1/EPB41/GPER1/KIF5B/PRKCE/CIB1/STAC3/CLN3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SQSTM1 32
GO:0097300 programmed necrotic cell death 25/3662 49/15509 2.81299e-05 0.000217936 0.000131063 BIRC3/FAS/BAX/DNM1L/ASAH1/PPIF/FASLG/RBCK1/IRF3/MUTYH/PARP1/OGT/TLR3/FADD/FZD9/MAP3K5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PGAM5 25
GO:0007409 axonogenesis 134/3662 415/15509 2.82735e-05 0.000218776 0.000131568 IFRD1/PAFAH1B1/CNTN1/SPAST/CDH1/EPHA3/LAMA3/NGFR/NTN1/FGFR2/EPHA8/MARK2/PICALM/GLI2/NOTCH3/ACTB/PLXNA2/EPHA6/GSK3B/RAB10/DPYSL2/HSP90AB1/ABL1/ADNP/BMP7/LAMA1/SCN1B/DVL1/GATA3/CXCL12/UNC5B/PPP3CB/WNT3/CNTNAP1/EFNB3/DBN1/WNT5A/TTL/ITGA4/FN1/STMN1/NRP2/SPP1/EGR2/USP9X/FLRT3/BCL11B/RAC2/CHN1/APOE/LAMA5/EPHB2/NOTCH2/NGF/LRP4/DBNL/NKX2-1/STXBP1/KIAA0319/TUBB2B/IGF1R/RNF165/SMAD4/APP/EPHA2/CRABP2/SLIT2/EPHA5/C9orf72/NTRK2/NOTCH1/PARD3/NCAM1/ITGB1/POU4F2/POU4F1/NR4A2/UCHL1/DPYSL5/B4GALT5/ISL2/ARHGAP35/SPTBN4/BRSK1/DISC1/SLC25A46/SHH/ADCY1/CDK5/TTC8/RHOH/SEMA4C/EFNA1/PTK2/SEMA3E/CDH2/KIF5B/NPTX1/LPAR3/MAP6/LAMB2/BSG/DAG1/CNP/BRSK2/BDNF/CDK5R1/CDH4/PTPN11/PAK2/ADGRB1/CSF1R/EPHB3/NOG/CNTN2/SLIT3/POU3F2/DCC/SYNGAP1/SIPA1L1/MBP/NTRK1/GDI1/TCTN1/TMEFF1/EFNA4/TWF2/TUBB3/EPHB6/NEFL/WNT3/WNT3/TBCE/PTEN 134
GO:0071560 cellular response to transforming growth factor beta stimulus 84/3662 238/15509 2.83847e-05 0.000219362 0.00013192 ITGA3/HSPA5/ARID4B/HIPK2/SPI1/FGFR2/HYAL2/ITGA8/FKBP1A/PXN/GLG1/HSP90AB1/ABL1/FERMT1/SMAD7/RBBP7/AXIN1/SFRP1/PDCD5/TGFB1/TGFBR1/ENG/BMPR1A/ZMIZ1/LPXN/FOLR1/ZNF451/IL4/SMAD5/WNT5A/STK16/HDAC1/ARG1/FMOD/USP9X/BMP2/ID1/PIN1/TWSG1/CDKN1C/GDF15/MEN1/SPRY2/NKX2-1/THBS1/SMAD6/TET1/FBN2/IGF1R/FURIN/ARRB2/SMAD4/PARP1/OGT/ZEB1/ZFP36L2/NODAL/APPL1/SKI/RBBP4/WNT4/TGFBR2/SAP30/GDF9/HTRA1/CX3CR1/ADAM9/PTK2/ZEB2/LIMS1/FOS/PDE3A/SMAD2/EID2/JUN/PAK2/ZNF703/ZFP36L1/BCL9L/SRC/TRIM33/SLC2A10/SPRED2/CDKN1C 84
GO:0045577 regulation of B cell differentiation 19/3662 33/15509 2.87195e-05 0.000221673 0.00013331 BAD/BTK/HMGB3/XBP1/SFRP1/IL7/BCL6/ID2/INHBA/IL10/IL2RG/ZFP36L2/MMP14/SYK/INPP5D/STAT5B/ZFP36L1/CR1/INPP5D 19
GO:0043484 regulation of RNA splicing 56/3662 144/15509 2.88651e-05 0.00022252 0.00013382 PTBP1/CLK1/DAZAP1/FAM50A/MBNL3/ATXN7L3/FUS/CIRBP/RBFOX2/ESRP1/SNRNP70/C1QBP/DDX5/ZPR1/HSPA8/SRSF9/FAM172A/KAT2B/NCL/SRSF7/SRSF4/PTBP2/PRDX6/PTBP3/SMU1/AHNAK/RBM42/HNRNPH2/GRSF1/SRPK2/HNRNPA1/TAF5L/SRSF1/NCBP1/TMBIM6/SF3B4/PIK3R1/WTAP/RBMX/MBNL1/TAF6L/RBM15/CCNL1/FASTK/CDK12/HNRNPH1/TADA3/LARP7/ERN1/NPM1/RBM10/TRRAP/CCNL2/RBM15B/RBM8A/SRSF1 56
GO:0045930 negative regulation of mitotic cell cycle 76/3662 211/15509 3.04682e-05 0.000234295 0.000140901 FHL1/YTHDC2/NDC80/ZW10/BIRC5/CDC6/MSH2/ABL1/BMP7/RBBP8/NBN/CASP2/EZH2/CCL2/CCND1/FBXO5/CCNG1/RAD50/BCL6/CDC20/PKD2/TEX14/INHBA/CDKN1A/CDKN1C/BTG1/CCNB1/CDCA8/APC/IL10/NABP2/RB1/DTL/INTS3/CTDSP1/PLK2/SPC25/ZFP36L2/XPC/EME1/BTG2/PRMT2/BRSK1/MRNIP/RPL26/BRD7/WEE1/RFWD3/BUB1/AVEN/CDK1/TRIAP1/NABP1/ZWILCH/ANGEL2/CTDSP2/AURKAIP1/AURKB/CACNB4/CHEK2/FOXO4/MUC1/ZFP36L1/KANK2/GIGYF2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PRKDC/CDKN1C/PTEN 76
GO:1903050 regulation of proteolysis involved in protein catabolic process 76/3662 211/15509 3.04682e-05 0.000234295 0.000140901 OSBPL7/RHBDF1/HFE/PSMC4/RNF14/UFL1/HERPUD1/HIPK2/ATXN3/SIRT2/CSNK2A2/PRKACA/MKRN2/SIRT6/UBE2K/GSK3B/XPO1/PSMC5/PSME1/HECTD1/BAG6/HSP90AB1/PSMC6/USP14/SMAD7/N4BP1/AXIN1/SGTA/GSK3A/DVL1/CTSC/USP5/PDCL3/PARK7/CDC20/RAD23B/CLU/PTK2B/USP9X/CBFA2T3/APOE/PSME3/HSPBP1/EGF/CSNK1D/GNA12/TLK2/OGT/EIF3H/ALAD/RNF144A/USP25/PSMC2/DISC1/RYBP/RCHY1/SHH/VCP/PSMC3/BTRC/EFNA1/PTK2/GLMN/MAGEF1/PRKN/USP7/SVIP/BAG6/BAG6/BAG6/BAG6/BAG6/CEBPA/PTEN/PRKACA/F8A1 76
GO:0031668 cellular response to extracellular stimulus 83/3662 235/15509 3.06699e-05 0.000235554 0.000141658 SNAI2/GLRX2/RRAGD/FAS/CASR/CLEC16A/HSPA5/EIF2AK2/ASNS/PTPRC/SEH1L/P2RX7/GCN1/COMT/SH3GLB1/XBP1/ADNP/NPRL3/SFRP1/TLE5/USF2/MAPK8/RNF167/HSPA8/FOLR1/CYP27B1/VDR/ITGA4/ELAPOR1/SLC2A1/FOXO3/TRIM24/CDKN1A/MAX/BECN1/ATG14/CD68/SESN2/PRKAA1/MYBBP1A/HNRNPA1/GLUL/TTC5/GABARAPL1/IGF1R/TNFRSF11A/PMAIP1/SESN3/FOXO1/NR4A2/KLF10/WIPI2/ARHGAP35/BRSK1/WNT4/VCAM1/ATF3/INHBB/ALB/RICTOR/AQP3/ZFYVE1/MN1/FOS/PPM1D/EIF2AK3/KAT5/BRSK2/LEP/LPL/FOSL1/PLEC/DCTPP1/GAS2L1/PRR5/AKR1C3/KANK2/MAP3K5/ATG7/MTOR/SIPA1/PTPRC/LOC102724560 83
GO:0042770 signal transduction in response to DNA damage 62/3662 164/15509 3.07441e-05 0.000235832 0.000141825 KDM1A/CRY1/SNAI2/CD74/CD44/USP28/RAD51/HIPK2/SP100/RPS6KA6/ZMPSTE24/ATRX/MSH2/ABL1/NBN/DOT1L/YJU2/CASP2/ZNHIT1/DDX5/CCND1/FOXM1/MAPK14/CCNG1/GADD45A/FOXO3/CDKN1A/SOX4/EEF1E1/SESN2/BRCA2/CUL4A/PMAIP1/DTL/DYRK3/PLK2/XPC/EME1/BRSK1/MRNIP/ZNF385A/RPL26/RFWD3/CDK1/PPM1D/TRIAP1/RHNO1/KAT5/GRB2/PTPN11/NPM1/CEP63/PTTG1IP/CHEK2/KMT5A/FOXO4/MUC1/H2AX/SPRED2/GIGYF2/PRKDC/MIF 62
GO:0002269 leukocyte activation involved in inflammatory response 26/3662 52/15509 3.08773e-05 0.000235977 0.000141913 TYROBP/GRN/PTPRC/CTSC/IFNG/IL4/CLU/NR1D1/SYT11/IL6/APP/ITGB2/TLR3/CX3CR1/ITGAM/JUN/TRPV1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC 26
GO:0043551 regulation of phosphatidylinositol 3-kinase activity 26/3662 52/15509 3.08773e-05 0.000235977 0.000141913 FGFR3/CDC42/EPHA8/PIK3IP1/PDGFB/FLT1/TGFB1/CCKBR/PDGFRB/CISH/TEK/PTK2B/FLT3/CCR7/ATG14/PDGFRA/CCL21/FGF2/PIK3R1/KIT/NOD2/PTK2/CCL19/CD19/SOCS1/SRC 26
GO:0070231 T cell apoptotic process 26/3662 52/15509 3.08773e-05 0.000235977 0.000141913 ST3GAL1/FAS/BAK1/ARG2/BAX/P2RX7/CLC/PRKD2/KDELR1/JAK3/WNT5A/FASLG/GPAM/BCL11B/IL2RA/BCL2L11/TSC22D3/RAG1/FADD/LGALS9/PRELID1/EFNA1/PTCRA/CHEK2/CCL5/CCL5 26
GO:0051656 establishment of organelle localization 126/3662 387/15509 3.17263e-05 0.000242167 0.000145635 PAFAH1B1/TRAPPC6A/STARD3NL/BTK/SPAST/CENPQ/GAB2/C12orf4/SYNE2/ATP9A/CDH3/AP3D1/NTN1/AP3M2/CDC42/FBXW11/NDE1/LLGL2/PICALM/MLH1/SPAG5/STXBP2/IL4R/PCM1/NDC80/XPO1/PIBF1/SEH1L/CHMP5/TMED2/LAT2/ZW10/NSFL1C/BIRC5/NUDC/SNAP29/MYH9/CHMP4B/GATA1/RAB11A/KXD1/PIK3CG/YKT6/LIN7A/IFNG/IL4/ARL6/KAT2B/SNX4/TTL/ITGA4/SDC1/TRAK2/VAMP8/PPP6C/NR4A3/WDR11/BECN1/UXT/RAC2/NECTIN2/CHMP1A/SYT11/AP3B1/CCNB1/PSRC1/CDCA8/BICDL1/LTV1/SPRY2/STXBP1/KIF13A/NUMA1/NUSAP1/CENPE/BBS4/CSNK1D/KIF2C/SNAPIN/CENPC/BOD1/CPLX2/PARD3/ITGB1/BICD1/GJA1/UCHL1/KIT/COPG2/TRAPPC10/LMNA/FYCO1/CDK5/GEM/SYK/CCDC186/BORCS7/LGALS9/NMD3/TRAPPC1/PDCD6IP/KIF5B/CFL1/KAT5/CHMP6/SYNE3/AURKB/MAPK15/NPM1/EXOC7/TRAK1/AP3M1/PRKN/HGS/CLN3/BLOC1S3/SDAD1/KIFC1/EIF6/PDCD6/TRAPPC2B/IKBKG/NDE1/NEFL/SPICE1/F8A1 126
GO:0030168 platelet activation 50/3662 125/15509 3.18018e-05 0.000242445 0.000145802 CD9/ACTB/PDGFB/MYH9/CTSG/CD40/GATA1/CD40LG/DGKH/PIK3CG/HSPB1/VWF/SH2B3/MAPK14/FN1/MPL/GNA13/APOE/PDGFRA/SERPINE2/IL6/STXBP1/TLR4/ADAMTS18/MERTK/DGKE/PRKCA/GNAQ/DMTN/ADAMTS13/PF4/PRKCD/F2RL2/NOS3/SYK/FUNDC2/C1GALT1C1/FGG/FGA/SELP/F2/F2R/ADRA2C/PLSCR1/BLOC1S3/PPIA/SRC/HBB/ITGB3/ADAMTS13 50
GO:0048771 tissue remodeling 58/3662 151/15509 3.20519e-05 0.000244051 0.000146768 WNT16/CD38/BAK1/FLT4/TIE1/ROCK1/NOX4/BAX/MMP2/P2RX7/RASSF2/ACP5/CSK/SFRP1/IL7/TGFB1/HAMP/PTN/MDK/CALCA/VDR/IL12B/IL1A/EPAS1/LEPR/TNFAIP3/ARG1/SPP1/PTK2B/IAPP/LIF/NOTCH2/IL6/IL21/DEF8/TNFRSF11A/EPHA2/IL18/GJA1/PRKCA/MMP14/RUNX1/TNFRSF11B/NOS3/SYK/RBPJ/INPP5D/ADRB2/S1PR1/GPR137/CSPG4/LEP/F2R/CSF1R/SRC/ITGB3/LOC102724560/INPP5D 58
GO:0006766 vitamin metabolic process 44/3662 106/15509 3.21572e-05 0.000244552 0.00014707 NPC1L1/SNAI2/SLC2A3/SLC46A1/MCCC1/LRP2/SLC23A2/ABCC1/PNPO/FOLR1/CYP27B1/IFNG/PPARD/MTR/SLC2A1/SLC19A2/UBIAD1/ALDH1A2/CBLIF/MMAB/CYP1A1/GSTO1/CYP3A4/GFI1/AMN/NNMT/MMADHC/SLC19A1/SHMT1/NQO1/TCN2/SLC52A2/AKR1C3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PDXP/THTPA/ABCC1 44
GO:1903076 regulation of protein localization to plasma membrane 43/3662 103/15509 3.33735e-05 0.000253491 0.000152445 ITGA3/EPHA3/ATP2B4/PICALM/ACTB/HECTD1/CSK/TGFB1/RANGRF/IFNG/TMEM59/VAMP8/LRP1/ACSL3/PPFIA1/EPHB2/EPHA2/STAC/PIK3R1/EGFR/ITGB1/MMP14/APPL1/RER1/LDLRAP1/AP2M1/GPER1/CDK5/KIF5B/PRKCE/BCL2L1/CIB1/STAC3/CLN3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SQSTM1 43
GO:0036035 osteoclast development 14/3662 21/15509 3.38899e-05 0.000257098 0.000154614 PAFAH1B1/TYROBP/LTF/ATP6AP1/LILRB1/NOTCH2/SLC9B2/FAM20C/ANXA2/SRC/LILRB1/LILRB1/LILRB1/LILRB1 14
GO:0050817 coagulation 77/3662 215/15509 3.39761e-05 0.000257438 0.000154819 SLC4A1/CD9/F7/LMAN1/ACTB/FBLN1/CD59/APOH/PDGFB/MYH9/CTSG/PROCR/CD40/GATA1/CD40LG/DGKH/PLAT/TFPI2/PIK3CG/HSPB1/SERPINE1/HGFAC/VWF/SH2B3/MAPK14/FN1/MPL/SERPINC1/GNA13/SEMG1/F13A1/APOE/AP3B1/EPHB2/PDGFRA/CD36/SERPINE2/IL6/STXBP1/TLR4/THBS1/ADAMTS18/GNA12/AK3/MERTK/DGKE/PRKCA/GNAQ/DMTN/ADAMTS13/PF4/PRKCD/ANXA5/F2RL2/SHH/NOS3/SYK/FUNDC2/HPS6/PRDX2/C1GALT1C1/FGG/FGA/JMJD1C/SELP/F2/F2R/ANXA2/ADRA2C/PLSCR1/BLOC1S3/PPIA/SRC/F5/HBB/ITGB3/ADAMTS13 77
GO:0021915 neural tube development 57/3662 148/15509 3.41387e-05 0.000258354 0.000155369 PRKACA/GLI2/PLXNA2/TULP3/LRP2/TMED2/KDM2B/HECTD1/ABL1/CECR2/MTHFD1/BMP7/TSC2/RPGRIP1L/SFRP1/TGFB1/DVL1/FOLR1/NPHP3/WNT5A/HES1/PKD2/MTHFD1L/GORAB/SOX4/ALDH1A2/RARA/CPLANE2/BBS4/EPHA2/NOTCH1/NODAL/SKI/ARHGAP35/DVL3/VANGL2/CASP3/SHH/SEMA4C/ARL13B/RARG/KAT5/GLMN/SETD2/RGMA/NOG/ZFP36L1/RNF220/ZNF358/BRD2/TCTN1/BRD2/BRD2/BRD2/BRD2/MARCKS/PRKACA 57
GO:0002688 regulation of leukocyte chemotaxis 48/3662 119/15509 3.51819e-05 0.000265924 0.000159922 CD74/F7/SPI1/DNM1L/PTN/SERPINE1/CREB3/CXCL12/C1QBP/CCL2/MDK/NEDD9/IL4/WNT5A/PADI2/PGF/PTK2B/CCR7/RAC2/MTUS1/IL6/CCN3/CCL21/THBS1/CYP19A1/SLIT2/VEGFC/CXCL13/IL6R/NOD2/CX3CR1/LGALS9/PTK2/CXCL8/CCL19/CALR/CXCR2/CSF1R/CSF1/HMGB1/DPP4/ZNF580/CCL5/CCL5/CCL4/CCL4/MIF/CCL4 48
GO:0034605 cellular response to heat 28/3662 58/15509 3.53198e-05 0.000266641 0.000160353 ATXN3/PRKACA/GSK3B/HSP90AB1/RBBP7/DNAJB6/CHORDC1/IL1A/THBS1/POLR2D/STAC/BAG3/CLPB/IER5/MAPKAPK2/VCP/IRAK1/TRPV1/MTOR/DAXX/DAXX/HSBP1L1/DAXX/DAXX/DAXX/PDCD6/CHORDC1/PRKACA 28
GO:0022602 ovulation cycle process 23/3662 44/15509 3.54622e-05 0.00026739 0.000160804 HSPA5/PGR/MMP2/ESR1/CASP2/MAP2K6/FOXO3/INHBA/PDGFRA/ARRB2/SLIT2/GAS2/ADAMTS1/CASP3/GDF9/NOS3/STAT5B/LEP/FZD4/A2M/SLIT3/ZP3/SRC 23
GO:0018393 internal peptidyl-lysine acetylation 63/3662 168/15509 3.55193e-05 0.000267496 0.000160867 NFYA/KMT2E/MED24/BAZ1B/SNAI2/FOXP3/NFYC/SPI1/MBD3/ACTB/ZMPSTE24/ATXN7L3/BRPF3/BAG6/SMARCB1/JADE3/GATA3/NAA40/ZNF451/KAT2B/SF3B1/PARK7/DR1/NAA50/MORF4L2/DEK/YEATS4/LIF/MYBBP1A/WBP2/TAF5L/EPC2/IRF4/ATAT1/BRCA2/SMAD4/OGT/KAT14/MBIP/SMARCA5/BRPF1/CTBP1/TAF6L/PYGO2/BRD7/SETD5/TADA3/HCFC1/KAT5/MSL2/TAF7/MUC1/NOC2L/WDR5/TRRAP/BAG6/BAG6/BAG6/BAG6/BAG6/SMARCB1/TADA2A/PCGF2 63
GO:0007435 salivary gland morphogenesis 20/3662 36/15509 3.61189e-05 0.000271681 0.000163384 SNAI2/HGF/FGFR2/BMP7/LAMA1/TGFB1/TWSG1/LAMA5/EGFR/SHH/DAG1/TGM2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 20
GO:0070228 regulation of lymphocyte apoptotic process 29/3662 61/15509 3.69922e-05 0.000277576 0.000166929 ST3GAL1/BTK/CD74/ARG2/BAX/P2RX7/BIRC7/PRKD2/JAK3/BCL6/WNT5A/GPAM/BCL11B/IL10/BCL2L11/TSC22D3/RAG1/FADD/LGALS9/PRELID1/EFNA1/PTCRA/ORMDL3/AURKB/NOC2L/CCL5/CCL5/MIF/PTEN 29
GO:2000379 positive regulation of reactive oxygen species metabolic process 29/3662 61/15509 3.69922e-05 0.000277576 0.000166929 TYROBP/CYBA/PDGFB/TGFB1/MAPK14/PDGFRB/PARK7/GADD45A/FOXO3/PTK2B/CDKN1A/CD36/TLR4/THBS1/CYP1B1/SOD1/ITGB2/TGFBR2/PRKCD/SYK/ITGAM/LEP/GRIN1/GRB2/F2/ADGRB1/AKR1C3/SLC5A3/CD177 29
GO:0051235 maintenance of location 103/3662 306/15509 3.70997e-05 0.000278046 0.000167212 CIAPIN1/SCIN/PAFAH1B1/CRY1/CD4/CPS1/HSPA5/HEXB/CYBA/SOAT1/AP3D1/SP100/PRKACA/LMAN1/PTPRC/APOB/FTL/BAX/FKBP1A/P2RX7/ABL1/RANGAP1/NFKBIA/SQLE/FCER2/KDELR1/PPARD/PDE4D/SKP1/DBN1/SLC30A3/PARK7/FASLG/PKD2/PTK2B/CRY2/SRGN/IL1B/SLC25A23/C3/CCR7/APOE/SYNE1/CD36/IL6/IL10/CCL21/TAF8/SORL1/ITGAV/COX17/FGF2/FBN2/BBS4/CALM2/OSBPL11/ANK2/GSN/LCN2/GSTO1/ITPR1/RER1/CALM3/CCR5/SELENON/SLC30A7/ALB/GPER1/CDK5/ZFYVE1/FTH1/LETM1/PRKCE/CCL19/STAT5B/RNF213/LEP/DDIT3/PTPN2/LPL/CD19/CALR/F2/F2R/SLC8A1/TRPV1/GM2A/SPOUT1/TNF/TMSB4X/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PISD/TWF2/ITGB3/PTPRC/RASA3/PRKACA 103
GO:0043414 macromolecule methylation 101/3662 299/15509 3.74586e-05 0.000280397 0.000168626 NFYA/KDM1A/KMT2E/PAF1/AASS/ARID4B/PRDM1/KDM4A/NFYC/SPI1/BUD23/MBD3/ZMPSTE24/ATRX/MECOM/DNMT3B/SMARCB1/SNRPD3/PCIF1/SETD6/DOT1L/FBL/GSK3A/EZH2/GATA3/TRDMT1/EZH1/NSD2/NOP2/HCFC2/MACROH2A1/KDM3A/ASH1L/NSUN4/MYB/PHF19/DNMT3A/HELLS/EEF1AKMT3/H1-3/PRMT1/ASH2L/PRDM12/DNMT1/PRMT7/MEN1/CMTR1/ALKBH8/THUMPD2/TET1/SNRPF/SKIC8/CYP1A1/SMAD4/CARM1/METTL25B/PARP1/SNRPG/BOD1/WTAP/OGT/NSD3/SMARCA5/RNF20/BTG2/PRMT2/LMNA/GFI1/RBM15/PYGO2/NSD1/NNMT/SNRPD1/GATAD2A/SETD5/H1-4/FOS/MGMT/PPM1D/COPRS/HCFC1/TRMT112/TDRD12/LARP7/WDR6/SUZ12/SETD2/SETD3/KMT5A/TET3/H1-2/TRMT2B/PAX5/WDR5/WDR5B/NCOA6/PCMTD2/RBM15B/SMARCB1/PAGR1/EMG1 101
GO:0010586 miRNA metabolic process 39/3662 91/15509 3.76881e-05 0.000281177 0.000169095 NGFR/SPI1/TUT7/PDGFB/TGFB1/GATA3/BMPR1A/DDX5/PPARD/MYB/FOXO3/EGR1/BMP2/RARA/IL10/SMAD6/FGF2/SMAD4/TERT/FOS/RELA/HRAS/FOSL1/JUN/LILRB4/TEAD1/MRTFA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GAS5/LILRB4/LILRB4/LILRB4 39
GO:0048145 regulation of fibroblast proliferation 39/3662 91/15509 3.76881e-05 0.000281177 0.000169095 IGF1/CD74/NGFR/FOSL2/SIRT6/ZMPSTE24/BAX/ESR1/CDC6/ABL1/PDGFB/SFRP1/MED25/ZMIZ1/PDGFRB/WNT5A/FN1/CDKN1A/LIF/CCNB1/PDGFRA/CCNA2/PDGFC/EGFR/SKI/TP53INP1/FTH1/LIG4/HRAS/JUN/C1QL4/LTA/LTA/LTA/LTA/LTA/BRK1/ITGB3/MIF 39
GO:0042886 amide transport 99/3662 292/15509 3.77438e-05 0.000281177 0.000169095 BAD/CD38/HFE/CD74/CASR/NNAT/SLC46A1/SIRT6/LRP2/OXCT1/ABCB1/RAPGEF4/PCK2/VAPA/ABCC1/SFRP1/PLEKHA8/TFR2/PPP3CB/FOLR1/PSMD9/IFNG/PPARD/PASK/PARK7/SLC19A2/ABCG2/CRHR1/SNX19/SERP1/SOX4/ABCC4/IL1B/NR1D1/PER2/HNF1A/GLUL/IL6/IL1RN/CCN3/SLC15A4/GLTP/SLC47A1/ENSA/EPHA5/SLC16A2/CAMK2G/GLUD1/TCF7L2/FOXO1/GJA1/SLC13A3/INHBB/AIMP1/SLC9B2/GPER1/AQP3/CCDC186/TAP1/PRKCE/FGG/FGA/SLC19A1/BRSK2/LEP/SMAD2/PTPN11/MAFA/PRKN/KCNJ11/TRPV1/PIM3/SELENOT/TAP2/TNF/TAP2/TAP1/TAP2/TNF/TAP2/TNF/TAP1/TAP2/TAP1/TAP1/TNF/TAP2/TNF/TNF/TNF/TAP1/TAPBP/TAP2/TNF/TAP2/RASL10B/CCL5/CCL5/ABCC1 99
GO:0044843 cell cycle G1/S phase transition 78/3662 219/15509 3.77444e-05 0.000281177 0.000169095 KMT2E/DBF4/PAF1/FHL1/ARID1B/ATP2B4/ACTB/PSME1/CDC6/CDC7/BCL7C/SMARCB1/CDKN3/APEX1/RBBP8/CCNE1/CASP2/EZH2/RPS6KB1/SMARCD2/CCL2/ZPR1/CCND1/BCL7A/CCND3/PPP2CA/ID2/ARID1A/PKD2/PPP6C/INHBA/CDKN1A/PSME3/MEN1/CCNH/APC/RDX/RB1/CUL4A/CYP1A1/CTDSP1/CCNA2/PLK2/EGFR/ITGB1/CACUL1/ADAMTS1/LSM11/APPL1/CUL4B/PRMT2/RPL26/GFI1/TERT/CDK5/BRD7/WEE1/RRM1/RFWD3/MN1/TRIAP1/RRM2/KLF11/CTDSP2/CCNE2/CACNB4/PLCB1/CHEK2/CDK10/MUC1/ARID2/KANK2/TFDP1/GIGYF2/PRKDC/SMARCB1/PAGR1/PTEN 78
GO:0048608 reproductive structure development 93/3662 271/15509 3.80848e-05 0.000283373 0.000170415 HOXA11/BAK1/HSPA5/ARID4B/MSH4/FGFR2/TP63/HOXA9/LRP2/PGR/ATRX/BAX/MMP2/ESR1/MSH2/BMP7/GATA1/PCYT1B/SFRP1/CASP2/TGFBR1/GATA3/CCND1/PDGFRB/WNT5A/IL1A/SDC1/ASH1L/KDM5B/FOXO3/EIF2B2/TNFSF10/INHBA/MEA1/C3/EIF2S2/KDR/SOX15/BCL2L2/RARA/HSD17B4/PDGFRA/SERPINE2/NKX2-1/CYP19A1/CYP1B1/BRCA2/GREB1L/ARRB2/SMAD4/SOD1/RAB13/REN/SLIT2/NOTCH1/GAS2/ARID5B/DHX37/BCL2L11/BMP6/MERTK/ADAMTS1/MMP14/KIT/WNT4/H3-3A/INHBB/CASP3/TLR3/GDF9/SHH/NOS3/FRS2/ZFPM2/BCL2L1/CEBPB/CYP7B1/RARG/STAT5B/LEP/FZD4/A2M/PTPN11/PLAG1/NOG/SLIT3/ZP3/AKR1C3/SRC/NTRK1/FANCG/HOXA10/PTEN 93
GO:0050792 regulation of viral process 55/3662 142/15509 3.86504e-05 0.000287236 0.000172739 CD4/LTF/CD74/EIF2AK2/MID2/MAVS/N4BP1/TRIM14/AICDA/STAT1/NR5A2/TRIM25/CXCR4/STAU1/ZFP36/NECTIN2/TOP2A/TRIM5/TRIM22/SRPK2/MDFIC/TARBP2/FURIN/GSN/NOTCH1/HMGA2/MBL2/TRIM68/LGALS9/CXCL8/TRIM8/LARP7/PDE12/BANF1/TMEM39A/CD28/CIITA/IFITM1/HEXIM1/PLSCR1/HMGB1/PPIA/TNF/TRIM13/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TRIM26/TMEM250/CCL5/CCL5 55
GO:0002562 somatic diversification of immune receptors via germline recombination within a single locus 31/3662 67/15509 3.92734e-05 0.000291168 0.000175103 PARP3/FOXP3/TCF3/TBX21/MLH1/PTPRC/MSH2/CD40/CD40LG/NBN/IL27RA/TGFB1/EXOSC3/NSD2/AICDA/IL4/BCL6/SHLD2/BCL11B/NDFIP1/IL10/SLC15A4/DCAF1/TNFSF13/RAG1/LIG4/RAG2/CD28/HMGB1/PRKDC/PTPRC 31
GO:0016444 somatic cell DNA recombination 31/3662 67/15509 3.92734e-05 0.000291168 0.000175103 PARP3/FOXP3/TCF3/TBX21/MLH1/PTPRC/MSH2/CD40/CD40LG/NBN/IL27RA/TGFB1/EXOSC3/NSD2/AICDA/IL4/BCL6/SHLD2/BCL11B/NDFIP1/IL10/SLC15A4/DCAF1/TNFSF13/RAG1/LIG4/RAG2/CD28/HMGB1/PRKDC/PTPRC 31
GO:0050848 regulation of calcium-mediated signaling 36/3662 82/15509 3.98143e-05 0.000292814 0.000176093 CD4/PTBP1/CD22/IGF1/ATP2B4/ERBB3/GSK3B/P2RX5/NFAT5/PPP3CB/ZAP70/FHL2/PTK2B/DYRK2/CALM2/ITPR1/SPPL3/CALM3/SYK/CHP2/HINT1/CIB1/P2RX2/MTOR/TNF/TNF/STIMATE/TNF/TNF/TNF/TNF/TNF/TNF/CCL4/CCL4/CCL4 36
GO:0031294 lymphocyte costimulation 24/3662 47/15509 3.98184e-05 0.000292814 0.000176093 CD40LG/CSK/MAP3K8/EFNB3/CD5/CD81/IL4/CD86/CD160/CD80/CCR7/CCL21/TNFRSF13C/CCL19/CD28/PTPN11/LILRB4/SRC/DPP4/PDCD1LG2/CD24/LILRB4/LILRB4/LILRB4 24
GO:0033628 regulation of cell adhesion mediated by integrin 24/3662 47/15509 3.98184e-05 0.000292814 0.000176093 SNAI2/EPHA8/FERMT1/PIEZO1/PIK3CG/SERPINE1/LPXN/LIF/PODXL/CCL21/CYP1B1/EPHA2/CXCL13/SYK/ADAM9/EFNA1/PTK2/PTPN11/CIB1/MUC1/DPP4/ITGB3/CCL5/CCL5 24
GO:0002292 T cell differentiation involved in immune response 32/3662 70/15509 3.99196e-05 0.000292814 0.000176093 TMEM98/FOXP3/TBX21/IL4R/IL12RB1/SMAD7/JAK3/GATA3/IFNG/IL12B/IL4/BCL6/CD86/MYB/CD80/RARA/IL6/HLX/IRF4/IL21/IL18/IL6R/LGALS9/CCL19/HMGB1/ENTPD7/MTOR/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 32
GO:0002438 acute inflammatory response to antigenic stimulus 18/3662 31/15509 3.99408e-05 0.000292814 0.000176093 BTK/FCGR2B/GATA3/PARK7/C3/CCR7/A2M/CXCR2/ZP3/ELANE/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/ELANE 18
GO:0034114 regulation of heterotypic cell-cell adhesion 18/3662 31/15509 3.99408e-05 0.000292814 0.000176093 CD44/CEACAM6/BMP7/IL1B/IL10/IL1RN/FGG/FGA/ADIPOQ/MBP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 18
GO:0045663 positive regulation of myoblast differentiation 18/3662 31/15509 3.99408e-05 0.000292814 0.000176093 ARID1B/ACTB/SMARCB1/SMARCD2/MAPK14/ARID1A/SOX4/BTG1/IGFBP3/XKR8/RANBP3L/HIF1AN/BRD7/KAT5/PLCB1/ARID2/MAP3K5/SMARCB1 18
GO:0060055 angiogenesis involved in wound healing 18/3662 31/15509 3.99408e-05 0.000292814 0.000176093 ADIPOR2/MCAM/XBP1/SERPINE1/SMOC2/TNFAIP3/CXCR4/KDR/DAG1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3 18
GO:0070920 regulation of production of small RNA involved in gene silencing by RNA 18/3662 31/15509 3.99408e-05 0.000292814 0.000176093 ZMPSTE24/ESR1/TGFB1/DDX5/MYCN/IL6/TARBP2/EGFR/TERT/TRUB1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 18
GO:0070886 positive regulation of calcineurin-NFAT signaling cascade 16/3662 26/15509 4.00623e-05 0.000292814 0.000176093 PTBP1/IGF1/ERBB3/PPP3CB/SPPL3/CHP2/CIB1/TNF/TNF/STIMATE/TNF/TNF/TNF/TNF/TNF/TNF 16
GO:0106058 positive regulation of calcineurin-mediated signaling 16/3662 26/15509 4.00623e-05 0.000292814 0.000176093 PTBP1/IGF1/ERBB3/PPP3CB/SPPL3/CHP2/CIB1/TNF/TNF/STIMATE/TNF/TNF/TNF/TNF/TNF/TNF 16
GO:1902004 positive regulation of amyloid-beta formation 16/3662 26/15509 4.00623e-05 0.000292814 0.000176093 PICALM/GSK3A/IFNG/CLU/SLC2A13/CASP3/EFNA1/RELA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 16
GO:0050000 chromosome localization 35/3662 79/15509 4.01878e-05 0.000293385 0.000176437 IFFO1/CENPQ/NDE1/MLH1/SPAG5/NDC80/PIBF1/SEH1L/CHMP5/ZW10/BIRC5/NUDC/CHMP4B/RAB11A/KAT2B/TTL/BECN1/CHMP1A/CCNB1/PSRC1/CDCA8/NUMA1/ACTR2/CENPE/KIF2C/CENPC/BOD1/LMNA/GEM/KAT5/CHMP6/AURKB/KIFC1/NDE1/SPICE1 35
GO:0030518 intracellular steroid hormone receptor signaling pathway 45/3662 110/15509 4.04707e-05 0.000295103 0.00017747 KDM1A/CRY1/RNF14/UFL1/PLPP1/RHOA/TP63/PIAS2/PGR/ESR1/RBFOX2/SFRP1/ZMIZ1/DDX5/KDM3A/PARK7/HDAC1/PADI2/ARID1A/CRY2/PKN1/CNOT1/YWHAH/WBP2/CARM1/PARP1/CNOT9/POU4F2/NODAL/PRMT2/HEYL/GPER1/TRIM68/TADA3/CYP7B1/TAF7/CALR/SRC/KANK2/DAXX/DAXX/DAXX/DAXX/DAXX/PAGR1 45
GO:0032956 regulation of actin cytoskeleton organization 107/3662 321/15509 4.18564e-05 0.000304848 0.00018333 SCIN/EPHA3/CYFIP2/RHOA/ROCK1/SPTB/CDC42/WDR1/ARHGEF10L/ADD2/ACTN2/ADD1/PXN/ABL1/HCK/COTL1/PYCARD/TJP1/SFRP1/ARHGEF10/MTPN/MET/TGFBR1/CXCL12/CSF3/MDK/ARPC3/FZD10/NEDD9/PDGFRB/DBN1/IL1A/CAPZA1/STMN1/TEK/PTK2B/LRP1/DSTN/ID1/CCR7/CDC42EP1/RAC2/ARPC1B/PPFIA1/WASF3/NOTCH2/PDGFRA/DBNL/CCL21/RDX/ABI2/BBS4/ARHGDIA/SMAD4/ABL2/RHOB/SLIT2/EPHA5/PIK3R1/IQGAP2/ARHGAP18/C9orf72/GSN/CDC42EP2/PLEKHH2/DMTN/ARHGAP35/SPTBN4/ALOX15/WNT4/ARPC5/ANKRD23/CDC42EP3/SPTA1/PRKCD/ARFIP1/RICTOR/CDK5/TTC8/RHOH/SEMA3E/S1PR1/PRKCE/CCL11/SPTBN2/HRAS/CDK5R1/FLII/GRB2/PAK2/CSF1R/CDK10/PRKN/NF2/CD47/GMFB/SPTAN1/MTOR/IQANK1/TMSB4X/PDXP/ARPC1A/TWF2/SHANK3/BRK1/ITGB3/TJP1 107
GO:2001242 regulation of intrinsic apoptotic signaling pathway 57/3662 149/15509 4.272e-05 0.000310773 0.000186893 BAD/KDM1A/NOX1/SNAI2/CD74/CD44/HERPUD1/TMEM161A/BAX/DNM1L/XBP1/MMP9/PYCARD/URI1/GSDME/HSPB1/CREB3/CXCL12/PPIF/SEPTIN4/PTPMT1/PARK7/HDAC1/HELLS/CLU/PLAGL2/BECN1/TRAP1/STYXL1/BCL2L2/EPO/SERINC3/BCL2L10/TMBIM6/PMAIP1/SOD1/PARP1/NONO/BCL2L11/ZNF385A/RPL26/TRIAP1/BCL2L1/EIF2AK3/DDIT3/PTPN2/GRINA/PTTG1IP/PRKN/MUC1/NOC2L/PPIA/SRC/NDUFS3/FIS1/MAGEA3/MIF 57
GO:1904375 regulation of protein localization to cell periphery 49/3662 123/15509 4.30188e-05 0.00031258 0.00018798 ITGA3/EPHA3/ATP2B4/PICALM/ACTB/GPC4/HECTD1/CSK/TGFB1/RANGRF/IFNG/TMEM59/VAMP8/LRP1/RAB38/ACSL3/PPFIA1/EPHB2/NUMA1/EPHA2/STAC/PIK3R1/EGFR/ITGB1/MMP14/APPL1/RER1/LDLRAP1/EPB41/AP2M1/GPER1/CDK5/KIF5B/PRKCE/BCL2L1/DAG1/HRAS/CIB1/STAC3/CLN3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SQSTM1 49
GO:0002577 regulation of antigen processing and presentation 13/3662 19/15509 4.33327e-05 0.000314124 0.000188909 HFE/SLC11A1/CD74/FCGR2B/PYCARD/NOD1/CCR7/CD68/CCL21/THBS1/NOD2/CCL19/HLA-DOA 13
GO:0090201 negative regulation of release of cytochrome c from mitochondria 13/3662 19/15509 4.33327e-05 0.000314124 0.000188909 IGF1/HGF/BAK1/PPIF/CLU/BCL2L2/ARRB2/LMNA/FXN/PRELID1/TRIAP1/BCL2L1/PRKN 13
GO:0007596 blood coagulation 76/3662 213/15509 4.39846e-05 0.000318409 0.000191486 SLC4A1/CD9/F7/LMAN1/ACTB/FBLN1/CD59/APOH/PDGFB/MYH9/CTSG/PROCR/CD40/GATA1/CD40LG/DGKH/PLAT/TFPI2/PIK3CG/HSPB1/SERPINE1/HGFAC/VWF/SH2B3/MAPK14/FN1/MPL/SERPINC1/GNA13/F13A1/APOE/AP3B1/EPHB2/PDGFRA/CD36/SERPINE2/IL6/STXBP1/TLR4/THBS1/ADAMTS18/GNA12/AK3/MERTK/DGKE/PRKCA/GNAQ/DMTN/ADAMTS13/PF4/PRKCD/ANXA5/F2RL2/SHH/NOS3/SYK/FUNDC2/HPS6/PRDX2/C1GALT1C1/FGG/FGA/JMJD1C/SELP/F2/F2R/ANXA2/ADRA2C/PLSCR1/BLOC1S3/PPIA/SRC/F5/HBB/ITGB3/ADAMTS13 76
GO:1904029 regulation of cyclin-dependent protein kinase activity 43/3662 104/15509 4.40265e-05 0.000318409 0.000191486 IPO5/ACTB/CCNK/CDC6/HSP90AB1/PDGFB/CDKN3/CCNE1/BCCIP/CCND1/GTF2H1/CCND3/CCNG1/KAT2B/CNPPD1/GADD45A/TNFAIP3/PKD2/CCNI/CDKN1A/PKMYT1/CDKN1C/CCNA1/MEN1/CCNB1/PSRC1/CCNH/APC/HERC5/CCNA2/EGFR/HHEX/CCNL1/CASP3/CKS1B/CCNE2/CDK5R1/HEXIM1/SRC/IPO7/CEBPA/CDKN1C/PTEN 43
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity 42/3662 101/15509 4.57722e-05 0.000330264 0.000198615 IPO5/ACTB/CCNK/CDC6/PDGFB/CDKN3/CCNE1/BCCIP/CCND1/GTF2H1/CCND3/CCNG1/KAT2B/CNPPD1/GADD45A/TNFAIP3/PKD2/CCNI/CDKN1A/PKMYT1/CDKN1C/CCNA1/MEN1/CCNB1/PSRC1/CCNH/APC/HERC5/CCNA2/EGFR/HHEX/CCNL1/CASP3/CKS1B/CCNE2/CDK5R1/HEXIM1/SRC/IPO7/CEBPA/CDKN1C/PTEN 42
GO:0034446 substrate adhesion-dependent cell spreading 42/3662 101/15509 4.57722e-05 0.000330264 0.000198615 PKP2/RHOA/CDC42/ST6GAL1/FBLN1/ITGA8/PXN/ABL1/OLFM4/ATRNL1/C1QBP/LPXN/MDK/CORO1C/NEDD9/BVES/ITGA4/FN1/TEK/LAMA5/LAMC1/ITGAV/PIK3R1/MERTK/DMTN/MELTF/EFNA1/PTK2/ANTXR1/LIMS1/FGG/FGA/LAMB2/FZD4/RCC2/CALR/EPHB3/CIB1/SPRY4/SRC/PARVA/ITGB3 42
GO:0050764 regulation of phagocytosis 41/3662 98/15509 4.74729e-05 0.000342136 0.000205755 BTK/SLC11A1/CYBA/FCGR2B/PTPRC/HCK/PYCARD/CSK/CCL2/IFNG/IL1B/C3/SYT11/SFTPD/CD36/ITGAV/SOD1/IL2RG/MERTK/APPL1/ALOX15/SYK/MBL2/NOD2/CALR/ADIPOQ/PLSCR1/HMGB1/PRTN3/CD47/TGM2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTPRC/PRTN3 41
GO:0001889 liver development 51/3662 130/15509 4.90793e-05 0.000353303 0.00021247 HGF/CPS1/CSNK2A2/ZMPSTE24/SMARCB1/XBP1/ACO2/PCK2/RPGRIP1L/HAMP/PTN/MET/EZH2/CCND1/MDK/NPHP3/HES1/TNFAIP3/ARG1/PKD2/ELK1/ALDH1A2/ASS1/RARA/NOTCH2/HNF1A/IL6/HLX/IL10/CYP1A1/NOTCH1/ARID5B/NODAL/WNT4/FRZB/CEBPB/RELA/TYMS/JUN/IGF2R/PHF2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/SMARCB1 51
GO:0046660 female sex differentiation 46/3662 114/15509 5.01719e-05 0.000360383 0.000216728 BAK1/HSPA5/MSH4/TP63/LRP2/PGR/BAX/MMP2/ESR1/PCYT1B/SFRP1/CASP2/WNT5A/FOXO3/EIF2B2/INHBA/KDR/PDGFRA/CYP19A1/BRCA2/ARRB2/SMAD4/SOD1/SLIT2/GAS2/ARID5B/MERTK/ADAMTS1/MMP14/KIT/WNT4/INHBB/CASP3/GDF9/NOS3/ZFPM2/BCL2L1/CEBPB/STAT5B/LEP/FZD4/A2M/SLIT3/ZP3/SRC/FANCG 46
GO:0010573 vascular endothelial growth factor production 22/3662 42/15509 5.01792e-05 0.000360383 0.000216728 NOX1/SARS1/FLT4/TGFB1/IL1A/IL1B/C3/IL6/CYP1B1/ARNT/NODAL/IL6R/NDRG2/EIF2AK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 22
GO:0032535 regulation of cellular component size 110/3662 333/15509 5.04416e-05 0.000361849 0.000217609 KDM1A/USH1C/IFRD1/SCIN/PAFAH1B1/CDH1/CYFIP2/NTN1/RHOA/SPTB/WDR1/PICALM/ADD2/ACTN2/GSK3B/PPP1R15A/ADD1/P2RX7/DPYSL2/HSP90AB1/ABL1/CDHR5/ADNP/HCK/COTL1/PYCARD/RAB11A/KCNN4/KXD1/MTPN/CXCL12/CSF3/WNT3/ARPC3/DBN1/WNT5A/TTL/FN1/CAPZA1/SPP1/PTK2B/DSTN/CCR7/HP1BP3/CDC42EP1/APOE/ARPC1B/NGF/DBNL/CCL21/KIAA0319/RDX/BBS4/CRABP2/SNAPIN/SLIT2/ARHGAP18/SLC12A9/MSN/GSN/CDC42EP2/POU4F2/PLEKHH2/DMTN/ARHGAP35/SPTBN4/AP2M1/ALOX15/ARPC5/DISC1/CDC42EP3/SPTA1/PRKCD/RICTOR/CDK5/BORCS7/SEMA4C/SEMA3E/PRKCE/LPAR3/CCL11/RARG/SPTBN2/BDNF/FLII/GRB2/CDH4/NPM1/CNTN2/DCC/WNT7B/LAMTOR4/CLN3/ABCB8/SPTAN1/MTOR/IQANK1/GDI1/AKT1S1/TMSB4X/PDXP/ARPC1A/TWF2/SHANK3/BRK1/AKT3/NEFL/WNT3/WNT3/PTEN 110
GO:0030851 granulocyte differentiation 19/3662 34/15509 5.07146e-05 0.000363386 0.000218534 SPI1/CEBPE/GATA1/CSF3/IL5/CBFA2T3/RARA/AP3B1/CUL4A/LBR/RUNX1/TAL1/BAP1/CSF2/INPP5D/ADIPOQ/L3MBTL3/CEBPA/INPP5D 19
GO:0061448 connective tissue development 85/3662 245/15509 5.18482e-05 0.00037108 0.000223161 HOXA11/SCIN/SNAI2/RUNX3/CD44/CASR/BARX2/PUM2/SPI1/HYAL2/FGFR3/PITX1/OXCT1/ZMPSTE24/GLG1/XBP1/PDGFB/BMP7/SMAD7/SLC39A14/TGFB1/HOXA5/TGFBR1/BMPR1A/ACTA2/ZBTB16/MDK/WNT5B/PPARD/MAPK14/SMAD5/PDGFRB/WNT5A/PRRX1/SNX19/EGR1/RUNX2/BMP2/THRA/HOXD3/TWSG1/COL5A1/RARA/CHI3L1/LOXL2/ADAMTS7/CCN3/SORL1/FGF2/COL2A1/RB1/BBS4/CCN1/NOTCH1/ZEB1/SERPINH1/HMGA2/ARID5B/POU4F2/BMP6/STC1/RUNX1/IL6R/FRZB/TGFBR2/BMP1/EIF2AK3/RARG/ESRRA/LEP/HRAS/PLAAT3/TYMS/MAF/PTPN11/CREB3L2/RFLNB/NOG/CSF1/WNT7B/COL27A1/COL11A2/EBF2/ITGB3/LOC102724560 85
GO:0045598 regulation of fat cell differentiation 50/3662 127/15509 5.19817e-05 0.000371606 0.000223477 SNAI2/TFE3/SIRT2/SIRT6/RUNX1T1/MMP11/XBP1/BMP7/AXIN1/SFRP1/TGFB1/GATA3/ZBTB16/PPARD/MAPK14/WNT5A/HES1/ID2/BMP2/NR1D1/ZFP36/IL6/ATAT1/TAF8/CARM1/DUSP10/FOXO1/ZFP36L2/WIF1/FNDC5/ZNF385A/FRZB/GPER1/ZFPM2/CEBPB/LEP/DDIT3/LPL/ADIPOQ/ZFP36L1/C1QL4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA 50
GO:0035065 regulation of histone acetylation 28/3662 59/15509 5.21724e-05 0.00037254 0.000224039 NFYA/KMT2E/BAZ1B/SNAI2/FOXP3/NFYC/SPI1/ZMPSTE24/SMARCB1/GATA3/ZNF451/SF3B1/PARK7/DEK/LIF/MYBBP1A/WBP2/SMAD4/SMARCA5/CTBP1/PYGO2/BRD7/SETD5/TAF7/MUC1/NOC2L/SMARCB1/TADA2A 28
GO:0006354 DNA-templated transcription elongation 76/3662 214/15509 5.26453e-05 0.000375484 0.00022581 PAF1/MED24/MED17/MED29/SIRT6/PIAS2/DDX1/PIR/KDM2B/PXN/FUS/CCNK/SUPT16H/MED15/SMARCB1/CBX7/AXIN1/ERCC2/MED25/POLR2I/ELL/EZH2/RECQL5/INTS2/SMARCD2/LPXN/POU2AF1/KAT2B/KDM3A/FHL2/ARID3A/KDM3B/MED13L/RALY/UXT/ADRM1/ZC3H4/PIAS3/BTG1/MED6/ELP2/AKIRIN2/NCBP1/HMGA1/INTS14/TDG/SKIC8/INTS3/PPRC1/HMGA2/ERCC3/RYBP/SAP30/SHH/MED30/INTS1/NSD1/CDK12/SETD5/JMJD1C/KAT5/KDM2A/LARP7/MED16/SETD2/EWSR1/MUC1/HEXIM1/TCEA1/NELFB/TRRAP/PHF2/ZXDA/ZBED1/SMARCB1/TAF15 76
GO:0006475 internal protein amino acid acetylation 63/3662 170/15509 5.36716e-05 0.000381586 0.000229479 NFYA/KMT2E/MED24/BAZ1B/SNAI2/FOXP3/NFYC/SPI1/MBD3/ACTB/ZMPSTE24/ATXN7L3/BRPF3/BAG6/SMARCB1/JADE3/GATA3/NAA40/ZNF451/KAT2B/SF3B1/PARK7/DR1/NAA50/MORF4L2/DEK/YEATS4/LIF/MYBBP1A/WBP2/TAF5L/EPC2/IRF4/ATAT1/BRCA2/SMAD4/OGT/KAT14/MBIP/SMARCA5/BRPF1/CTBP1/TAF6L/PYGO2/BRD7/SETD5/TADA3/HCFC1/KAT5/MSL2/TAF7/MUC1/NOC2L/WDR5/TRRAP/BAG6/BAG6/BAG6/BAG6/BAG6/SMARCB1/TADA2A/PCGF2 63
GO:1903078 positive regulation of protein localization to plasma membrane 29/3662 62/15509 5.39265e-05 0.000381586 0.000229479 ITGA3/EPHA3/ATP2B4/RANGRF/IFNG/LRP1/ACSL3/EPHB2/EPHA2/STAC/PIK3R1/EGFR/ITGB1/RER1/GPER1/KIF5B/PRKCE/CIB1/STAC3/CLN3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/SQSTM1 29
GO:0002249 lymphocyte anergy 12/3662 17/15509 5.4055e-05 0.000381586 0.000229479 FOXP3/CLC/LILRB4/HLA-B/HLA-B/HLA-B/HLA-B/HLA-B/LILRB4/LILRB4/LILRB4/ITCH 12
GO:0002667 regulation of T cell anergy 12/3662 17/15509 5.4055e-05 0.000381586 0.000229479 FOXP3/CLC/LILRB4/HLA-B/HLA-B/HLA-B/HLA-B/HLA-B/LILRB4/LILRB4/LILRB4/ITCH 12
GO:0002870 T cell anergy 12/3662 17/15509 5.4055e-05 0.000381586 0.000229479 FOXP3/CLC/LILRB4/HLA-B/HLA-B/HLA-B/HLA-B/HLA-B/LILRB4/LILRB4/LILRB4/ITCH 12
GO:0002911 regulation of lymphocyte anergy 12/3662 17/15509 5.4055e-05 0.000381586 0.000229479 FOXP3/CLC/LILRB4/HLA-B/HLA-B/HLA-B/HLA-B/HLA-B/LILRB4/LILRB4/LILRB4/ITCH 12
GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator 12/3662 17/15509 5.4055e-05 0.000381586 0.000229479 HIPK2/SP100/RPS6KA6/ZNHIT1/FOXM1/CDKN1A/BRCA2/ZNF385A/RPL26/KAT5/CHEK2/MUC1 12
GO:0032817 regulation of natural killer cell proliferation 12/3662 17/15509 5.4055e-05 0.000381586 0.000229479 IL12B/PTPN22/IL18/STAT5B/LEP/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 12
GO:1901856 negative regulation of cellular respiration 12/3662 17/15509 5.4055e-05 0.000381586 0.000229479 RHOA/PPIF/TRAP1/PDE12/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 12
GO:0031645 negative regulation of nervous system process 15/3662 24/15509 5.42533e-05 0.000382116 0.000229798 TMEM98/CTSC/IL10/CCN3/TNFRSF21/EIF2AK3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTEN 15
GO:0033598 mammary gland epithelial cell proliferation 15/3662 24/15509 5.42533e-05 0.000382116 0.000229798 BAX/ESR1/HOXA5/GATA3/AREG/CCND1/WNT5A/ID2/KDM5B/BRCA2/EPHA2/PYGO2/BTRC/CEBPB/ZNF703 15
GO:0007229 integrin-mediated signaling pathway 44/3662 108/15509 5.51694e-05 0.000388127 0.000233413 ITGAL/ITGA3/ITGA2B/LAMA3/CDC42/ADAM11/ITGA8/ABL1/MYH9/FERMT1/HCK/LAMA1/CD40LG/PTN/NEDD9/ITGA4/FN1/PTK2B/LAMA5/LAMC1/CCM2/ITGA11/ITGAV/ITGAX/ITGB1/DST/ADAMTS1/DMTN/ITGB2/ADAMTS13/SYK/ADAM9/PTK2/LIMS1/ITGAM/LAMB2/RCC2/PTPN11/CD47/SRC/SLC2A10/CD177/ITGB3/ADAMTS13 44
GO:0002828 regulation of type 2 immune response 17/3662 29/15509 5.54445e-05 0.00038962 0.000234311 CD74/TBX21/IL4R/ARG2/IL27RA/GATA3/CD81/IL4/BCL6/CD86/ARG1/NDFIP1/RARA/IL6/HLX/IL18/NOD2 17
GO:0006809 nitric oxide biosynthetic process 31/3662 68/15509 5.59757e-05 0.0003926 0.000236103 ATP2B4/ARG2/HSP90AB1/CYB5R3/ACP5/IFNG/MTARC2/PKD2/CLU/PTK2B/IL1B/ASS1/CD36/IL10/TLR4/CYP1B1/DDAH1/NOS3/CX3CR1/NQO1/TRPV1/CD47/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HBB 31
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process 34/3662 77/15509 5.59953e-05 0.0003926 0.000236103 HGF/BIRC3/CD44/BIRC5/MMP9/BIRC7/GPI/DNAJB6/CRYAB/PARK7/NR4A1/MICAL1/THBS1/ARRB2/FABP1/INTS1/RAG1/SERPINB9/TRIAP1/PAK2/SRC/TNF/TNF/MAGEA3/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NAIP/GPI 34
GO:0050688 regulation of defense response to virus 33/3662 74/15509 5.63391e-05 0.000394565 0.000237284 FOXP3/ZMPSTE24/MAVS/IL12RB1/RIOK3/PYCARD/LILRB1/C1QBP/IL12B/IL4/STAT1/TNFAIP3/IL1B/TRAF3/PTPN22/PPM1B/HERC5/TARBP2/NLRX1/HTRA1/TRIM44/PCBP2/MICB/MICB/MICB/MICB/MICB/MICB/LILRB1/LILRB1/LILRB1/LILRB1/ITCH 33
GO:0046683 response to organophosphorus 48/3662 121/15509 5.8126e-05 0.00040662 0.000244534 KDM1A/CPS1/HSPA5/KCNQ1/P2RX5/P2RX7/APEX1/GATA1/PLAT/PIK3CG/AHR/RAPGEF1/AREG/STAT1/SDC1/PKD2/PTK2B/IL1B/FOSB/CDO1/ASS1/NT5E/FDX1/CYP1B1/SOD1/APP/CARM1/PKLR/REN/DMTN/STC1/INHBB/GPD1/PTAFR/FOS/BSG/PDE3A/FOSL1/TYMS/ADIPOQ/SLC8A1/ZFP36L1/KCNJ11/P2RX2/TRPV1/PDXP/P2RY11/PKLR 48
GO:0010634 positive regulation of epithelial cell migration 52/3662 134/15509 5.8483e-05 0.000408656 0.000245759 ITGA3/GRN/FLT4/FGFR1/ABL1/PDGFB/MMP9/CD40/RAB11A/GPI/PRKD2/TGFB1/PIK3CG/MET/HSPB1/GATA3/IFNG/SMOC2/HBEGF/WNT5A/NRP2/TEK/PTK2B/RRAS/STAT5A/KDR/THBS1/FGF2/EGF/RHOB/PLK2/VEGFC/PRKCA/EMC10/TGFBR2/NOS3/MAPRE2/ADAM9/PTK2/PRKCE/JUN/CALR/CIB1/HMGB1/SRC/MTOR/TMSB4X/ZNF580/PDCD6/ITGB3/AKT3/GPI 52
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 113/3662 345/15509 6.00155e-05 0.000418892 0.000251914 ITGA3/HFE/HSPA5/ARID4B/HIPK2/SPI1/ITGA8/LRP2/FKBP1A/PXN/GLG1/HSP90AB1/ABL1/BMP7/FERMT1/SMAD7/RBBP7/AXIN1/SFRP1/TGFB1/SFRP4/TGFBR1/ENG/BMPR1A/DKK1/ZMIZ1/DDX5/LPXN/FOLR1/MAPK14/ZNF451/SMAD5/WNT5A/HES1/HDAC1/TGIF2/SFRP5/EGR1/FMOD/INHBA/LRP1/USP9X/RUNX2/BMP2/ID1/PIN1/KDR/TWSG1/CDKN1C/GDF15/MEN1/NOTCH2/SPRY2/NKX2-1/CCN3/KIAA0319/NUMA1/SORL1/THBS1/SMAD6/TET1/FBN2/FURIN/TOB1/ARRB2/RNF165/SMAD4/CCN1/PARP1/OGT/NOTCH1/ZEB1/CRIM1/BMP6/NODAL/APPL1/SKI/RBBP4/INHBB/TGFBR2/SAP30/GDF9/ELAPOR2/SHH/HTRA1/RBPJ/ADAM9/PTK2/ZEB2/FOS/RGMB/SMAD2/EID2/JUN/RGMA/NOG/ZNF703/BCL9L/TMPRSS6/MAGI2/FAM83G/SRC/TRIM33/SLC2A10/SPRED2/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CDKN1C/CRIM1/ZNF8 113
GO:0007431 salivary gland development 20/3662 37/15509 6.12138e-05 0.000426775 0.000256655 SNAI2/HGF/FGFR2/BMP7/LAMA1/TGFB1/TWSG1/LAMA5/EGFR/SHH/DAG1/TGM2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 20
GO:0019079 viral genome replication 47/3662 118/15509 6.13579e-05 0.000427299 0.00025697 LTF/YTHDC2/EIF2AK2/ATG16L1/MAVS/CCNK/SMARCB1/VAPA/N4BP1/CCL2/HSPA8/AICDA/NR5A2/STAU1/DEK/TOP2A/SRPK2/TARBP2/NOTCH1/HMGA2/EEF1A1/CTBP1/VCP/ATG16L2/CXCL8/PDE12/CTBP2/BANF1/TMEM39A/CD28/PRKN/IFITM1/PLSCR1/PPIA/PCBP2/TNF/TNF/ZBED1/TNF/TNF/TNF/TNF/TNF/TNF/CCL5/CCL5/SMARCB1 47
GO:0007565 female pregnancy 61/3662 164/15509 6.1829e-05 0.000430097 0.000258653 CD38/ITGA3/PRDM1/VMP1/EPN1/DAZAP1/FBLN1/PGR/OVGP1/TMED2/MMP2/ESR1/ANGPT2/MMP9/SYDE1/KLF1/PTN/AMBP/C1QBP/CALCA/CYP27B1/VDR/PPARD/IGFBP2/ASH1L/SLC2A1/ARG1/SPP1/PGF/CRHR1/RECK/IL1B/FOSB/LIF/EPO/RARA/MEN1/SOD1/PARP1/CORIN/GJA1/NODAL/STC1/WNT4/CAPN2/H3-3A/TGFBR2/LGALS9/FOS/BSG/SLC19A1/STAT5B/LEP/FOSL1/CALR/OXTR/PAPPA/YTHDF3/EPOR/ITGB3/LOC102724560 61
GO:0046545 development of primary female sexual characteristics 41/3662 99/15509 6.27247e-05 0.00043535 0.000261812 HSPA5/MSH4/PGR/BAX/MMP2/ESR1/PCYT1B/SFRP1/CASP2/FOXO3/EIF2B2/INHBA/KDR/PDGFRA/CYP19A1/BRCA2/ARRB2/SMAD4/SOD1/SLIT2/GAS2/ARID5B/ADAMTS1/MMP14/KIT/WNT4/INHBB/CASP3/GDF9/NOS3/ZFPM2/BCL2L1/CEBPB/STAT5B/LEP/FZD4/A2M/SLIT3/ZP3/SRC/FANCG 41
GO:0071347 cellular response to interleukin-1 41/3662 99/15509 6.27247e-05 0.00043535 0.000261812 UPF1/HYAL2/MMP2/CD40/CCL22/CCL17/PYCARD/SFRP1/CCL2/IL17A/HES1/CCL20/EGR1/IL1B/NR1D1/AKAP12/IL6/ADAMTS7/TANK/IL1RN/CCL21/RBMX/INHBB/TNIP2/CXCL8/FGG/CCL11/CEBPB/CCL19/RELA/PLCB1/IRAK1/CD47/CCL5/CCL5/CCL4/CCL18/CCL4/CCL4/CCL18/CCL18 41
GO:0031099 regeneration 66/3662 181/15509 6.41946e-05 0.000445054 0.000267648 IFRD1/CD9/IGF1/HGF/BAK1/GRN/F7/PTPRU/CSNK2A2/MMP2/ANGPT2/PRPS2/GATA1/HAMP/MTPN/PTN/EZH2/CXCL12/CCND1/FOLR1/MDK/CD81/PPARD/KPNA1/BCL9/PRRX1/MTR/SPP1/NR4A3/PGF/FLT3/CDKN1A/SOX15/LCP1/IL6/IL10/CCN3/KIAA0319/TARBP2/IGF1R/DUSP10/CCNA2/NOTCH1/RUNX1/SELENON/TGFBR2/NNMT/CDK1/LAMB2/CEBPB/DAG1/TYMS/JUN/RGMA/FZD9/IGF2R/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEFL/PTEN 66
GO:0043244 regulation of protein-containing complex disassembly 46/3662 115/15509 6.46862e-05 0.000447961 0.000269396 UPF1/SCIN/SPAST/CLEC16A/PHF23/NAV3/TBC1D25/SPTB/WDR1/ADD2/ACTN2/ZMPSTE24/ADD1/TPX2/MTPN/CAPZA1/MTRF1/DSTN/APC/RDX/IGF1R/GSN/PLEKHH2/SCAF4/DMTN/SPTBN4/SPTA1/FYCO1/ADRB2/SPTBN2/TMEM39A/FLII/CIB1/CLN3/SPTAN1/IQANK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PDXP/TWF2 46
GO:0045579 positive regulation of B cell differentiation 11/3662 15/15509 6.50695e-05 0.000449611 0.000270388 BAD/BTK/XBP1/IL7/IL10/IL2RG/MMP14/SYK/INPP5D/STAT5B/INPP5D 11
GO:0090324 negative regulation of oxidative phosphorylation 11/3662 15/15509 6.50695e-05 0.000449611 0.000270388 RHOA/PPIF/PDE12/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 11
GO:0043087 regulation of GTPase activity 110/3662 335/15509 6.65808e-05 0.000459541 0.00027636 PAFAH1B1/TRAPPC6A/RABGAP1/EPHA3/TBC1D22A/RASGRF1/ZC3H15/TBC1D25/RASGRP2/PICALM/PLXNA2/RAP1GAP/GSK3B/TMED2/GMIP/RAPGEF4/RANGAP1/CD40/CCL22/CCL17/TSC2/PYCARD/SFRP1/ARHGEF10/SYDE1/MET/EZH2/RAPGEF1/CCL2/CORO1C/FZD10/NEDD9/BVES/BCL6/WNT5A/CCL20/SIPA1L2/STMN1/PTK2B/TBC1D15/CCR7/PIN1/CHN1/AJUBA/FOXJ1/DOCK6/TBC1D14/TBC1D8B/SPRY2/CCL21/RDX/BBS4/ARRB2/SOD1/EPHA2/PKP4/EPHA5/IQGAP2/MMUT/C9orf72/NTRK2/ITGB1/ASAP2/CXCL13/AGAP1/ARHGAP27/ABR/ARHGAP35/DVL3/WNT4/RICTOR/GAPVD1/ARHGAP12/TTC8/MAPRE2/SLC27A4/TBC1D2B/RGS14/PTK2/LIMS1/S1PR1/CCL11/CCL19/HRAS/ALS2CL/RCC2/ARHGAP45/F2R/RGMA/EPHB3/PRTN3/TBC1D9B/SYNGAP1/SIPA1L1/NTRK1/MTOR/TGM2/SIPA1/CCPG1/CCL5/CCL5/TBC1D3/CCL4/CCL18/CCL4/PRTN3/CCL4/CCL18/CCL18/RASA3 110
GO:0006334 nucleosome assembly 45/3662 112/15509 6.81005e-05 0.000468985 0.00028204 ATRX/SUPT16H/CHRAC1/MACROH2A1/H1-3/H2BC11/HP1BP3/ANP32B/SSRP1/SMARCA5/H2BC5/CHAF1B/PADI4/H3-3A/CHAF1A/H1-4/NPM1/H2BC21/H1-2/H2AX/H1-0/H2BC26/BRD2/DAXX/DAXX/DNAJC9/BRD2/DAXX/DAXX/BRD2/DAXX/H2BC15/BRD2/BRD2/H4C15/H4C14/H4C12/H2BC6/H3C6/H4C5/H4C4/H2BC7/H3C10/PADI4/H3C2 45
GO:0030278 regulation of ossification 45/3662 112/15509 6.81005e-05 0.000468985 0.00028204 LTF/ZMPSTE24/TXLNG/P2RX7/BMP7/SMAD7/GATA1/SFRP1/TGFB1/PTN/BMPR1A/DKK1/ZBTB16/MDK/CALCA/CYP27B1/VDR/MAPK14/WNT5A/PTK2B/SRGN/EGR2/RUNX2/BMP2/LRP4/TFAP2A/SMAD6/FBN2/CCN1/NOTCH1/BMP6/WNT4/RBPJ/ADRB2/S1PR1/ESRRA/FAM20C/PTPN11/SLC8A1/RFLNB/CSF1/NOTUM/PBX1/FZD9/RXRB 45
GO:0030879 mammary gland development 49/3662 125/15509 6.99544e-05 0.000481218 0.000289396 NTN1/FGFR2/GLI2/HOXA9/PGR/BAX/ESR1/XBP1/USF2/HOXA5/GATA3/WNT3/AREG/CCND1/VDR/SLC29A1/WNT5A/ID2/KDM5B/IRF6/ARG1/STAT5A/HOXD9/CDO1/CYP19A1/FGF2/EGF/BRCA2/TNFRSF11A/EPHA2/BCL2L11/ARHGAP35/WNT4/PYGO2/TGFBR2/BTRC/MGMT/CCL11/CEBPB/STAT5B/OXTR/CSF1R/ZNF703/CSF1/WNT7B/SRC/NME1/WNT3/WNT3 49
GO:0048146 positive regulation of fibroblast proliferation 26/3662 54/15509 7.05086e-05 0.000484492 0.000291365 IGF1/CD74/NGFR/FOSL2/SIRT6/ESR1/CDC6/ABL1/PDGFB/ZMIZ1/PDGFRB/WNT5A/FN1/CDKN1A/LIF/CCNB1/PDGFRA/CCNA2/PDGFC/EGFR/LIG4/HRAS/JUN/BRK1/ITGB3/MIF 26
GO:0006606 protein import into nucleus 56/3662 148/15509 7.06938e-05 0.000485227 0.000291807 POLA2/CDH1/TNPO3/IPO5/ELAVL1/HYAL2/SIRT6/TNPO1/IPO11/MAVS/NUP50/HSP90AB1/NFKBIA/FERMT1/NXT2/KPNA3/TSC2/TGFB1/TNPO2/RANGRF/ZPR1/IFNG/MAPK14/KPNA1/TARDBP/CRY2/CSE1L/CDKN1A/NUP153/NUP85/NXT1/IPO8/CD36/MDFIC/AKIRIN2/PIK3R1/NOTCH1/BAG3/RANBP2/HEATR3/APPL1/LMNA/PRKCD/SHH/SYK/CHP2/PKIG/CDK1/LEP/PTTG1IP/IPO4/IPO9/IPO7/TXNIP/SQSTM1/IPO4 56
GO:0061458 reproductive system development 93/3662 275/15509 7.10824e-05 0.000487169 0.000292975 HOXA11/BAK1/HSPA5/ARID4B/MSH4/FGFR2/TP63/HOXA9/LRP2/PGR/ATRX/BAX/MMP2/ESR1/MSH2/BMP7/GATA1/PCYT1B/SFRP1/CASP2/TGFBR1/GATA3/CCND1/PDGFRB/WNT5A/IL1A/SDC1/ASH1L/KDM5B/FOXO3/EIF2B2/TNFSF10/INHBA/MEA1/C3/EIF2S2/KDR/SOX15/BCL2L2/RARA/HSD17B4/PDGFRA/SERPINE2/NKX2-1/CYP19A1/CYP1B1/BRCA2/GREB1L/ARRB2/SMAD4/SOD1/RAB13/REN/SLIT2/NOTCH1/GAS2/ARID5B/DHX37/BCL2L11/BMP6/MERTK/ADAMTS1/MMP14/KIT/WNT4/H3-3A/INHBB/CASP3/TLR3/GDF9/SHH/NOS3/FRS2/ZFPM2/BCL2L1/CEBPB/CYP7B1/RARG/STAT5B/LEP/FZD4/A2M/PTPN11/PLAG1/NOG/SLIT3/ZP3/AKR1C3/SRC/NTRK1/FANCG/HOXA10/PTEN 93
GO:0010950 positive regulation of endopeptidase activity 59/3662 158/15509 7.11338e-05 0.000487169 0.000292975 BAD/CASP10/FAS/BAK1/CYFIP2/NGFR/RHOA/PICALM/BAX/PSME1/MEFV/PYCARD/PDCD5/NOD1/CASP2/PERP/HSPE1/FASLG/TNFSF10/SEMG1/ADRM1/PSME3/AKIRIN2/ANP32B/MTCH1/BCL2L10/PMAIP1/CCN1/ARL6IP5/GSN/BCL2L11/NODAL/GPER1/SYK/VCP/FADD/LGALS9/PRELID1/EFNA1/EIF2AK3/GRIN1/F2R/CARD9/HMGB1/DAPK1/MAP3K5/MBP/CR1/TNF/PSENEN/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/PDCD6 59
GO:0002532 production of molecular mediator involved in inflammatory response 37/3662 87/15509 7.19264e-05 0.000492053 0.000295912 BTK/GRN/IL4R/MEFV/PYCARD/SERPINE1/EZH2/MAPK14/IL17A/SNX4/VAMP8/EPHB2/CD36/IL6/TLR4/DUSP10/GBP5/APPL1/BAP1/SYK/NOD2/PRDX2/LEP/F2/LILRB4/CARD9/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/LILRB4/LILRB4/LILRB4 37
GO:0031649 heat generation 14/3662 22/15509 7.29077e-05 0.000496028 0.000298303 IL1A/IL1B/EDNRB/TNFRSF11A/ADRB2/TRPV1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 14
GO:0036005 response to macrophage colony-stimulating factor 14/3662 22/15509 7.29077e-05 0.000496028 0.000298303 DOK1/SPP1/TLR4/PTPN2/CSF1R/CSF1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 14
GO:0046639 negative regulation of alpha-beta T cell differentiation 14/3662 22/15509 7.29077e-05 0.000496028 0.000298303 RUNX3/FOXP3/CBFB/TBX21/IL4R/SMAD7/JAK3/IL4/BCL6/HLX/RUNX1/SHH/SOCS1/HMGB1 14
GO:0072567 chemokine (C-X-C motif) ligand 2 production 14/3662 22/15509 7.29077e-05 0.000496028 0.000298303 CD74/TLR4/LPL/HMGB1/MBP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MIF 14
GO:2000341 regulation of chemokine (C-X-C motif) ligand 2 production 14/3662 22/15509 7.29077e-05 0.000496028 0.000298303 CD74/TLR4/LPL/HMGB1/MBP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/MIF 14
GO:0032715 negative regulation of interleukin-6 production 27/3662 57/15509 7.3607e-05 0.000500237 0.000300834 HGF/FOXP3/CSK/IL27RA/TNFAIP3/FOXJ1/SYT11/PTPN22/IL10/TLR4/ARRB2/NLRX1/INPP5D/LILRB4/TNF/TNF/TNF/TNF/TNF/TNF/ORM1/TNF/TNF/LILRB4/LILRB4/LILRB4/INPP5D 27
GO:0051591 response to cAMP 36/3662 84/15509 7.38509e-05 0.000501345 0.0003015 KDM1A/CPS1/HSPA5/KCNQ1/APEX1/GATA1/PLAT/PIK3CG/AHR/RAPGEF1/AREG/STAT1/SDC1/PKD2/PTK2B/FOSB/CDO1/ASS1/FDX1/CYP1B1/APP/CARM1/PKLR/REN/DMTN/STC1/INHBB/GPD1/PTAFR/FOS/BSG/FOSL1/ADIPOQ/SLC8A1/ZFP36L1/PKLR 36
GO:0045727 positive regulation of translation 48/3662 122/15509 7.41176e-05 0.000502003 0.000301896 ELAVL1/PKM/RHOA/PPP1R15A/GCN1/CIRBP/PCIF1/LARP4B/RPS6KB1/C1QBP/PASK/SERP1/PTK2B/SOX4/NIBAN1/IL6/THBS1/CYP1B1/LARP1B/TARBP2/TOB1/EIF4A3/POLR2D/CDC123/GUF1/RMND1/USP16/RPL26/RPUSD4/PTAFR/PAIP1/CD28/NPM1/EIF3C/YTHDF3/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/PRKDC/CCL5/CCL5 48
GO:0060693 regulation of branching involved in salivary gland morphogenesis 10/3662 13/15509 7.41908e-05 0.000502003 0.000301896 SNAI2/HGF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 10
GO:2000669 negative regulation of dendritic cell apoptotic process 10/3662 13/15509 7.41908e-05 0.000502003 0.000301896 LILRB1/CXCL12/CCR7/CCL21/BCL2L1/CCL19/LILRB1/LILRB1/LILRB1/LILRB1 10
GO:0042116 macrophage activation 43/3662 106/15509 7.5131e-05 0.000507257 0.000305055 TYROBP/SLC11A1/CD74/GRN/KARS1/FCGR2B/IL4R/PTPRC/HAMP/CTSC/IFNG/IL4/WNT5A/CLU/NR1D1/SYT11/IL6/IL10/TLR4/THBS1/APP/ITGB2/TLR3/CSF2/SYK/CX3CR1/TNIP2/ITGAM/PRKCE/JUN/TRPV1/SHPK/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/PTPRC/MIF 43
GO:0051983 regulation of chromosome segregation 43/3662 106/15509 7.5131e-05 0.000507257 0.000305055 CDC27/ARID1B/PUM2/SIRT2/CSNK2A2/ACTB/NDC80/ZW10/ANAPC5/BIRC5/CDC6/BCL7C/SMARCB1/SMARCD2/BCL7A/FBXO5/SMC4/KAT2B/CDC20/ARID1A/TEX14/BECN1/CCNB1/CDCA8/APC/NUMA1/CENPE/RB1/KIF2C/NCAPG2/MKI67/SPC25/BRD7/BUB1/KAT5/ZWILCH/RMI2/AURKB/RCC2/MAPK15/PLSCR1/ARID2/SMARCB1 43
GO:0051353 positive regulation of oxidoreductase activity 28/3662 60/15509 7.5936e-05 0.000512134 0.000307988 CYBA/CDH3/ABL1/FCER2/NOD1/CYP27B1/VDR/IFNG/PARK7/PTK2B/IL1B/APOE/FDX1/COX17/ABL2/CALM3/TERT/FXN/NOD2/PDP2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 28
GO:0001701 in utero embryonic development 115/3662 354/15509 7.64605e-05 0.000515055 0.000309745 PSMC4/IGF1/RCN1/PRDM1/EPN1/TIE1/FGFR2/MBD3/APOB/TMED2/HECTD1/MSH2/SMARCB1/PDGFB/MYH9/CCNB1IP1/CHD8/GINS1/BMP7/RBBP8/GATA1/AXIN1/RPGRIP1L/NBN/ERCC2/GPI/ELL/SMG9/DNAJB6/TGFBR1/GATA3/BMPR1A/SH3PXD2A/ZMIZ1/ZPR1/DBN1/HES1/EPAS1/MFN2/PKD2/GNA13/CNOT1/BMP2/EIF2S2/PRMT1/SBDS/LIF/SOX15/CCNB1/NOTCH2/PDGFRA/CCM2/NMT1/IL10/TAF8/TET1/CIR1/BRCA2/CUL4A/FURIN/ARMC5/CMTM3/SMAD4/FKBP10/ZFP14/CCN1/ARNT/RPL7L1/GNA12/EGFR/NCAPG2/NOTCH1/ITGB1/SEC24D/MBNL1/BCL2L11/GABPA/PHF6/NODAL/PLCD3/CAPN2/TGFBR2/BAP1/CSF2/NOS3/INTS1/RPL13/NXN/RBPJ/ZFPM2/BCL2L1/RRM2/CEBPB/ARNT2/LIG4/SMAD2/FOSL1/GRB2/SETD2/PHLDA2/NOG/ZFP36L1/WNT7B/ZP3/RRP7A/SLC35E2B/MAFG/ZNF568/TCTN1/CEBPA/BRK1/SMARCB1/PCGF2/GPI/EMG1 115
GO:0071480 cellular response to gamma radiation 16/3662 27/15509 7.67866e-05 0.000515055 0.000309745 KDM1A/HSPA5/RAD51/CYBA/XRCC5/ZMPSTE24/CRYAB/EGR1/CDKN1A/ELK1/TLK2/RPL26/BCL2L1/HRAS/CHEK2/H2AX 16
GO:0001794 type IIa hypersensitivity 9/3662 11/15509 7.73663e-05 0.000515055 0.000309745 FCGR2B/C3/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 9
GO:0002445 type II hypersensitivity 9/3662 11/15509 7.73663e-05 0.000515055 0.000309745 FCGR2B/C3/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 9
GO:0002465 peripheral tolerance induction 9/3662 11/15509 7.73663e-05 0.000515055 0.000309745 FOXP3/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 9
GO:0002725 negative regulation of T cell cytokine production 9/3662 11/15509 7.73663e-05 0.000515055 0.000309745 HFE/FOXP3/TBX21/SMAD7/ARG1/LILRB4/LILRB4/LILRB4/LILRB4 9
GO:0046136 positive regulation of vitamin metabolic process 9/3662 11/15509 7.73663e-05 0.000515055 0.000309745 IFNG/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 9
GO:0061044 negative regulation of vascular wound healing 9/3662 11/15509 7.73663e-05 0.000515055 0.000309745 SERPINE1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 9
GO:0061757 leukocyte adhesion to arterial endothelial cell 9/3662 11/15509 7.73663e-05 0.000515055 0.000309745 ZDHHC21/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 9
GO:0090235 regulation of metaphase plate congression 9/3662 11/15509 7.73663e-05 0.000515055 0.000309745 SPAG5/BIRC5/KAT2B/TTL/BECN1/CDCA8/NUMA1/KAT5/AURKB 9
GO:1901671 positive regulation of superoxide dismutase activity 9/3662 11/15509 7.73663e-05 0.000515055 0.000309745 PARK7/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 9
GO:1903347 negative regulation of bicellular tight junction assembly 9/3662 11/15509 7.73663e-05 0.000515055 0.000309745 ROCK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 9
GO:0002548 monocyte chemotaxis 29/3662 63/15509 7.75439e-05 0.000515131 0.000309791 PDGFB/CTSG/FLT1/CCL22/CCL17/SERPINE1/CREB3/CXCL12/CCL2/CALCA/CCL20/IL6/CCN3/CCL21/TNFRSF11A/SLIT2/IL6R/CX3CR1/CCL11/CCL19/HMGB1/CCL5/CCL5/CCL4/CCL18/CCL4/CCL4/CCL18/CCL18 29
GO:0051568 histone H3-K4 methylation 29/3662 63/15509 7.75439e-05 0.000515131 0.000309791 NFYA/KDM1A/KMT2E/NFYC/DNMT3B/GATA3/HCFC2/MACROH2A1/ASH1L/MYB/H1-3/ASH2L/DNMT1/MEN1/SKIC8/SMAD4/BOD1/OGT/GFI1/PYGO2/NNMT/H1-4/HCFC1/TET3/H1-2/WDR5/WDR5B/NCOA6/PAGR1 29
GO:0061008 hepaticobiliary system development 51/3662 132/15509 7.82934e-05 0.000519553 0.00031245 HGF/CPS1/CSNK2A2/ZMPSTE24/SMARCB1/XBP1/ACO2/PCK2/RPGRIP1L/HAMP/PTN/MET/EZH2/CCND1/MDK/NPHP3/HES1/TNFAIP3/ARG1/PKD2/ELK1/ALDH1A2/ASS1/RARA/NOTCH2/HNF1A/IL6/HLX/IL10/CYP1A1/NOTCH1/ARID5B/NODAL/WNT4/FRZB/CEBPB/RELA/TYMS/JUN/IGF2R/PHF2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA/SMARCB1 51
GO:0071479 cellular response to ionizing radiation 30/3662 66/15509 7.84891e-05 0.000520295 0.000312896 KDM1A/SNAI2/HSPA5/RAD51/CYBA/XRCC5/ZMPSTE24/SFRP1/EEF1D/HAMP/GATA3/CRYAB/MAPK14/GADD45A/EGR1/CDKN1A/ELK1/TANK/BRCA2/RHOB/TLK2/RPL26/MGMT/BCL2L1/RHNO1/LIG4/HRAS/GRB2/CHEK2/H2AX 30
GO:0071901 negative regulation of protein serine/threonine kinase activity 42/3662 103/15509 7.87108e-05 0.000521207 0.000313445 IPO5/HYAL2/ABL1/BMP7/PYCARD/SFRP1/CHORDC1/SH2B3/MACROH2A1/KAT2B/PRKAR2A/GADD45A/TNFAIP3/CDKN1A/IL1B/BMP2/CDKN1C/APOE/MEN1/PTPN22/APC/SPRY2/SORL1/RB1/DUSP10/HHEX/UCHL1/PRKCD/DUSP7/CASP3/PKIG/RGS14/ADIPOQ/SLC8A1/HEXIM1/SPRY4/IPO7/CEBPA/CDKN1C/LRP6/PTEN/CHORDC1 42
GO:0071260 cellular response to mechanical stimulus 31/3662 69/15509 7.88356e-05 0.000521476 0.000313607 BAD/MAP3K14/FAS/BAK1/CYBA/MAP2K4/CD40/TLR8/PIEZO1/MTPN/CASP2/ENG/MAPK8/GADD45A/SLC2A1/TNFRSF10B/TNFRSF8/KCNJ2/IL1B/TLR4/FGF2/IGF1R/BAG3/BMP6/TLR3/FADD/MAP3K2/DAG1/PLEC/TLR7/ITGB3 31
GO:0051170 import into nucleus 57/3662 152/15509 8.17204e-05 0.000539982 0.000324735 POLA2/CDH1/TNPO3/IPO5/ELAVL1/HYAL2/SIRT6/TNPO1/IPO11/MAVS/NUP50/HSP90AB1/NFKBIA/FERMT1/NXT2/KPNA3/TSC2/TGFB1/TNPO2/RANGRF/ZPR1/IFNG/MAPK14/KPNA1/TARDBP/CRY2/CSE1L/CDKN1A/NUP153/NUP85/NXT1/IPO8/CD36/MDFIC/AKIRIN2/HNRNPA1/PIK3R1/NOTCH1/BAG3/RANBP2/HEATR3/APPL1/LMNA/PRKCD/SHH/SYK/CHP2/PKIG/CDK1/LEP/PTTG1IP/IPO4/IPO9/IPO7/TXNIP/SQSTM1/IPO4 57
GO:0007005 mitochondrion organization 148/3662 475/15509 8.19265e-05 0.000540767 0.000325208 BAD/AGK/GGCT/TTC19/DCN/IGF1/HGF/ZDHHC6/TOMM34/BAK1/AIFM2/PUM2/VPS35/CSNK2A2/MARK2/LMAN1/GSK3B/BAX/DNM1L/P2RX7/TMEM14A/SH3GLB1/TIMM13/SAMM50/GZMB/TIMM9/MMP9/TSC2/PYCARD/PDCD5/MYH14/GSK3A/MAPK8/TFAM/PPIF/CNTNAP1/NDUFC1/GRPEL1/FOXRED1/HSPA9/SLC25A36/TRAK2/EPAS1/PARK7/MFN2/HMGCL/RAB32/NDUFA8/SLIRP/IFIT2/CLU/IAPP/TNFSF10/ATPAF1/RAB38/SIRT5/MGME1/BECN1/ATG14/KDR/RAC2/BCL2L2/ECSIT/NECTIN2/SESN2/TIMM10B/IMMT/PRKAA1/CLUH/AP3B1/HRK/NMT1/COX17/GABARAPL1/PIF1/ARRB2/PMAIP1/SAE1/PARP1/OGT/NDUFB9/IMMP1L/TIMM8B/NDUFC2/NUBPL/BAG3/BCL2L11/WIPI2/NDUFS2/THEM4/CALM3/LMNA/SELENON/OMA1/BAP1/SLC25A46/TERT/GPER1/NOS3/CDK5/FXN/FUNDC2/RRM1/NDUFS5/LETM1/MFF/PRELID1/TRIAP1/NPTX1/BCL2L1/SLC25A33/TOMM20/CNP/ATG13/TOMM5/MTX3/MIEF2/ACAD9/PLEC/HIGD1A/COA4/TRAK1/PRKN/UBE2L3/FZD9/ATG7/ATAD3A/UBL5/ND6/COX20/HSPA1L/RIMOC1/HSPA1L/NDUFS3/FIS1/FANCG/HSPA1L/HSPA1L/HSPA1L/PISD/MTFP1/CEBPA/PGAM5/TIMM23/AKT3/MARCKS/SQSTM1/TOP3A 148
GO:0045444 fat cell differentiation 77/3662 220/15509 8.22249e-05 0.000542159 0.000326045 SNAI2/TFE3/SIRT2/SIRT6/RUNX1T1/MMP11/XBP1/BMP7/AXIN1/SFRP1/TGFB1/GATA3/ZBTB16/CCND1/WNT5B/PPARD/MAPK14/WNT5A/HES1/ID2/NR4A3/EGR2/NR4A1/BMP2/NR1D1/ZFP36/PER2/PDGFRA/IL6/ATAT1/TAF8/SMAD6/BBS4/NUDT7/CARM1/DUSP10/OSBPL11/TCF7L2/HMGA2/ARID5B/FOXO1/ZFP36L2/NR4A2/WIF1/CTBP1/FNDC5/ZNF385A/FRZB/INHBB/GPER1/TTC8/ADRB2/ZFPM2/CEBPB/LEP/CTBP2/DDIT3/LPL/ADIPOQ/PLCB1/CNTN2/SOCS1/ZFP36L1/C1QL4/GRK5/MAFB/TNF/TNF/EBF2/CEBPD/TNF/TNF/TNF/TNF/TNF/TNF/CEBPA 77
GO:0018394 peptidyl-lysine acetylation 65/3662 179/15509 8.37998e-05 0.000551956 0.000331937 NFYA/KMT2E/MED24/BAZ1B/SNAI2/FOXP3/NFYC/SPI1/MBD3/ACTB/ZMPSTE24/ATXN7L3/BRPF3/BAG6/SMARCB1/JADE3/GATA3/NAA40/ZNF451/KAT2B/SF3B1/PARK7/DR1/NAA50/MORF4L2/SOX4/DEK/YEATS4/LIF/PRKAA1/MYBBP1A/WBP2/TAF5L/EPC2/IRF4/ATAT1/BRCA2/SMAD4/OGT/KAT14/MBIP/SMARCA5/BRPF1/CTBP1/TAF6L/PYGO2/BRD7/SETD5/TADA3/HCFC1/KAT5/MSL2/TAF7/MUC1/NOC2L/WDR5/TRRAP/BAG6/BAG6/BAG6/BAG6/BAG6/SMARCB1/TADA2A/PCGF2 65
GO:0015833 peptide transport 87/3662 255/15509 8.43161e-05 0.000554768 0.000333628 BAD/CD38/HFE/CD74/CASR/NNAT/SIRT6/OXCT1/RAPGEF4/PCK2/ABCC1/SFRP1/TFR2/PPP3CB/PSMD9/IFNG/PPARD/PASK/PARK7/CRHR1/SNX19/SERP1/SOX4/ABCC4/IL1B/NR1D1/PER2/HNF1A/GLUL/IL6/IL1RN/CCN3/SLC15A4/ENSA/EPHA5/SLC16A2/CAMK2G/GLUD1/TCF7L2/FOXO1/GJA1/SLC13A3/INHBB/AIMP1/SLC9B2/GPER1/CCDC186/TAP1/PRKCE/FGG/FGA/BRSK2/LEP/SMAD2/PTPN11/MAFA/PRKN/KCNJ11/TRPV1/PIM3/SELENOT/TAP2/TNF/TAP2/TAP1/TAP2/TNF/TAP2/TNF/TAP1/TAP2/TAP1/TAP1/TNF/TAP2/TNF/TNF/TNF/TAP1/TAPBP/TAP2/TNF/TAP2/RASL10B/CCL5/CCL5/ABCC1 87
GO:0062012 regulation of small molecule metabolic process 98/3662 294/15509 8.62192e-05 0.000566688 0.000340796 BAD/SLC4A1/CRY1/MBTPS2/IGF1/SNAI2/CD74/H6PD/ATP2B4/PDK3/ACADVL/SIRT6/DUSP12/PIBF1/ZMPSTE24/APOB/DNM1L/P2RX7/GSK3A/CYP27B1/IFNG/PPARD/IL4/KAT2B/PARK7/LEPR/NR4A3/EGR1/PTK2B/EPHX2/CD244/SIRT5/IL1B/BMP2/NR1D1/DYRK2/CBFA2T3/APOE/SESN2/PRKAA1/PMAIP1/SOD1/APP/ARNT/PARP1/IGFBP3/OGT/ERLIN2/SOGA1/FOXO1/NDUFC2/BMP6/RANBP2/KIT/LDLRAP1/ADIPOR1/SLC2A6/AK4/WNT4/GFI1/FABP1/GPER1/NOS3/VCP/NNMT/SLC27A4/GPD1/DDIT4/PTAFR/PRKCE/PGAM1/ARV1/MST1/LEP/PTPN2/DNAJC30/ERFE/LACC1/ADIPOQ/KLHL25/PRKN/USP7/CLN3/AKR1C3/WDR5/SRC/MTOR/TNF/TMSB4X/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/EIF6 98
GO:0002418 immune response to tumor cell 19/3662 35/15509 8.64512e-05 0.00056701 0.00034099 AHR/IL12B/CD160/NECTIN2/MR1/PRF1/MICA/HMGB1/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/MICA/HLA-A/MICA/MICA/HLA-A 19
GO:1901889 negative regulation of cell junction assembly 19/3662 35/15509 8.64512e-05 0.00056701 0.00034099 ROCK1/DKK1/CORO1C/WNT5A/IL1B/THBS1/MMP14/DMTN/RCC2/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTEN 19
GO:0016311 dephosphorylation 105/3662 319/15509 8.66256e-05 0.000567553 0.000341317 PTBP1/PPP5C/PHLPP2/PTPRU/MTMR1/PLPP1/ROCK1/INPP5A/SMG6/FBXW11/SYNJ2/PTPRC/DUSP12/GSK3B/PPP1R15A/FKBP1A/HSP90AB1/PPP6R2/CDKN3/CDC25B/PPP1R16B/ACP5/EYA1/URI1/TGFB1/CD33/PPP3CB/LHPP/PTPMT1/PPM1H/IFNG/PTP4A1/PPP2R5D/PPP2CA/PDGFRB/PTPA/PPP6C/MASTL/EPHX2/CRY2/BMP2/PIN1/STYXL1/PTPN22/PPM1B/DUSP5/MTMR6/IMPA2/ENSA/DUSP10/ACP1/CALM2/CTDSP1/BOD1/GNA12/PLPP5/PPP4C/PPP2R5E/SPPL3/DUSP2/PPP1R15B/CALM3/SSU72/PRKCD/DUSP7/NSMF/BTRC/CHP2/PPP2R3B/INPP5D/PPM1D/PDP2/CTDSP2/PTPN2/ANKLE2/PTPN11/PPP1R2/PTP4A3/INPP5J/MAGI2/PPIA/SRC/MTOR/SMG5/CSNK2B/TNF/PPP1R11/TNF/SACM1L/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PDXP/PGAM5/THTPA/PTPRC/INPP5D/PTEN 105
GO:0031295 T cell costimulation 23/3662 46/15509 8.77229e-05 0.00057353 0.000344911 CD40LG/CSK/MAP3K8/EFNB3/CD5/CD81/CD86/CD160/CD80/CCR7/CCL21/TNFRSF13C/CCL19/CD28/PTPN11/LILRB4/SRC/DPP4/PDCD1LG2/CD24/LILRB4/LILRB4/LILRB4 23
GO:0043537 negative regulation of blood vessel endothelial cell migration 23/3662 46/15509 8.77229e-05 0.00057353 0.000344911 ATP2B4/RHOA/ANGPT2/TGFB1/GADD45A/APOE/THBS1/FGF2/NOTCH1/HMGB1/CSNK2B/TNF/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B 23
GO:0002690 positive regulation of leukocyte chemotaxis 39/3662 94/15509 8.94062e-05 0.000582691 0.00035042 CD74/F7/SPI1/DNM1L/PTN/SERPINE1/CREB3/CXCL12/C1QBP/MDK/NEDD9/IL4/WNT5A/PGF/PTK2B/CCR7/RAC2/IL6/CCL21/THBS1/VEGFC/CXCL13/IL6R/CX3CR1/LGALS9/PTK2/CXCL8/CCL19/CALR/CXCR2/CSF1R/CSF1/HMGB1/ZNF580/CCL5/CCL5/CCL4/CCL4/CCL4 39
GO:0008637 apoptotic mitochondrial changes 39/3662 94/15509 8.94062e-05 0.000582691 0.00035042 BAD/GGCT/IGF1/HGF/BAK1/AIFM2/VPS35/GSK3B/BAX/DNM1L/TMEM14A/GZMB/MMP9/PYCARD/PDCD5/GSK3A/MAPK8/PPIF/IFIT2/CLU/TNFSF10/BCL2L2/HRK/NMT1/ARRB2/PMAIP1/BCL2L11/THEM4/LMNA/GPER1/FXN/MFF/PRELID1/TRIAP1/NPTX1/BCL2L1/PRKN/FZD9/FIS1 39
GO:0019218 regulation of steroid metabolic process 39/3662 94/15509 8.94062e-05 0.000582691 0.00035042 MBTPS2/SNAI2/H6PD/DDX20/ACADVL/APOB/ASAH1/CYP27B1/IFNG/PDE8B/IL1A/EGR1/EPHX2/BMP2/NR1D1/APOE/PRKAA1/IGF1R/ARMC5/SOD1/ERLIN2/BMP6/KIT/LDLRAP1/WNT4/GFI1/ATP1A1/ARV1/STAT5B/LEP/AKR1C3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 39
GO:0048568 embryonic organ development 135/3662 428/15509 8.97917e-05 0.000584589 0.000351562 WNT16/HOXA11/USH1C/ALX4/KCNQ1/PRDM1/EPN1/HIPK2/NTN1/FGFR2/NDST1/CDC42/MBD3/GLI2/ITGA8/TULP3/HOXA9/TMED2/KDM2B/HECTD1/PDGFB/MTHFD1/BMP7/GATA1/NDRG4/EYA1/TGFB1/DNAJB6/HOXA5/TGFBR1/ENG/DVL1/GATA3/CDH23/BMPR1A/HOXB6/FOLR1/SH2B3/SOBP/NPHP3/WNT5A/HES1/ID2/EPAS1/PRRX1/PKD2/MTHFD1L/RUNX2/KDR/LIF/HOXD3/HOXD9/ALDH1A2/SOX15/RARA/EPHB2/NOTCH2/PDGFRA/AHI1/SPRY2/HLX/IL10/TFAP2A/TUBB2B/FBN2/COL2A1/BBS4/EIF4A3/SOD1/EPHA2/CCN1/ARNT/LRIG1/PDGFC/EGFR/NOTCH1/ZEB1/NODAL/MMP14/KIT/PLCD3/TAL1/VANGL2/FRZB/ERCC3/TGFBR2/PITX2/IL3/CSF2/SHH/FRS2/RBPJ/EFNA1/ARL13B/CXCL8/ZFPM2/HOXD4/CEBPB/RARG/HOXB2/SMAD2/A2M/GRB2/SETD2/PHLDA2/NKX2-5/NOG/PBX1/ZFP36L1/TEAD1/WNT7B/ARID2/PAX5/COL13A1/HOXA4/LHFPL5/ZNF568/MAFB/PBX2/TNF/PBX2/TNF/TNF/PBX2/PBX2/TNF/TNF/TNF/TNF/TNF/PBX2/PBX2/CEBPA/PCGF2/TPO 135
GO:0016236 macroautophagy 90/3662 266/15509 9.03943e-05 0.000587895 0.00035355 DCN/UFL1/IFT88/ATP6V0A1/CLEC16A/PHF23/VMP1/TBC1D25/VPS35/PRKACA/ATG16L1/CHMP5/NSFL1C/SH3GLB1/SNAP29/CHMP4B/TSC2/NOD1/MAPK8/IL4/SNX4/ATP6V1A/ELAPOR1/MFN2/ATP6V0B/VAMP8/STBD1/CAPNS1/BECN1/ATG14/KDR/SESN2/CHMP1A/VPS25/TBC1D14/ARL8B/SNX14/VPS36/ATP6V1G1/GABARAPL1/ULK3/RETREG3/SNAPIN/KLHL3/OGT/ATP6V1B2/C9orf72/SESN3/EI24/VTI1A/BAG3/HSPB8/UCHL1/ATP6V1C1/WIPI2/FYCO1/CASP3/CDK5/TP53INP1/VCP/ZFYVE1/NOD2/UBXN6/ATG16L2/ADRB2/SNX32/RNF213/ATP2A2/ATG13/CHMP6/TMEM39A/CDK5R1/ERN1/YOD1/EXOC7/PRKN/HGS/CLN3/SRC/ATG7/MTOR/RNF5/TRIM13/RIMOC1/PGAM5/IKBKG/LIX1L/PIP4K2B/SQSTM1/PRKACA 90
GO:0090100 positive regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 44/3662 110/15509 9.23321e-05 0.000599868 0.00036075 HFE/HIPK2/ITGA8/HSP90AB1/BMP7/FERMT1/AXIN1/TGFB1/TGFBR1/ENG/BMPR1A/HES1/INHBA/BMP2/KDR/TWSG1/CDKN1C/GDF15/MEN1/NOTCH2/KIAA0319/NUMA1/THBS1/RNF165/SMAD4/CCN1/PARP1/NOTCH1/BMP6/NODAL/INHBB/TGFBR2/GDF9/ELAPOR2/RBPJ/ZEB2/SMAD2/SLC2A10/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CDKN1C 44
GO:0009749 response to glucose 61/3662 166/15509 9.25644e-05 0.000600748 0.000361279 BAD/CASR/CYBA/RHOA/PDK3/PRKACA/OPRK1/OXCT1/NOX4/ICAM1/ANGPT2/SMARCB1/XBP1/PCK2/SLC39A14/PPP3CB/RPS6KB1/PPARD/SLC29A1/FOXO3/EIF2B2/GPAM/EGR1/PTK2B/SOX4/NKX2-2/NR1D1/SESN2/PRKAA1/MEN1/GLUL/THBS1/KHK/IGF1R/SMAD4/COL6A2/PKLR/EPHA5/TCF7L2/TGFBR2/SLC9B2/CASP3/GPER1/CCDC186/PRKCE/NPTX1/KAT5/BRSK2/SMAD2/LPL/ERN1/RMI1/ADIPOQ/MAFA/SLC8A1/PIM3/SELENOT/PKLR/TXNIP/SMARCB1/PRKACA 61
GO:0044703 multi-organism reproductive process 66/3662 183/15509 9.39682e-05 0.000607019 0.000365051 CD38/ITGA3/TAC1/PRDM1/VMP1/EPN1/DAZAP1/FBLN1/PGR/OVGP1/TMED2/MMP2/ESR1/ANGPT2/MMP9/SYDE1/KLF1/PTN/AMBP/C1QBP/CALCA/CYP27B1/VDR/PPARD/IGFBP2/ASH1L/SLC2A1/ARG1/SPP1/PGF/CRHR1/RECK/SEMG1/IL1B/FOSB/LIF/EPO/RARA/MEN1/SERPINE2/CYP1A1/SOD1/PARP1/CORIN/GJA1/NODAL/STC1/WNT4/CAPN2/H3-3A/TGFBR2/LGALS9/PTAFR/FOS/BSG/SLC19A1/STAT5B/LEP/FOSL1/CALR/OXTR/PAPPA/YTHDF3/EPOR/ITGB3/LOC102724560 66
GO:0051701 biological process involved in interaction with host 66/3662 183/15509 9.39682e-05 0.000607019 0.000365051 CD4/LTF/CD74/THOC3/HYAL2/MID2/CHMP5/ICAM1/HSP90AB1/CHMP4B/VAPA/KPNA3/SLC1A5/TRIM14/EFNB3/CD81/CD86/VAMP8/TRIM25/CD80/CXCR4/NUP153/NECTIN2/CHMP1A/TRIM5/TRIM22/SFTPD/ARL8B/ITGAV/SLC7A1/FURIN/EPHA2/EGFR/GSN/NCAM1/ITGB1/CCR5/INHBB/THOC7/ANPEP/TRIM68/SLC3A2/LGALS9/CXCL8/GYPA/CDK1/TRIM8/BCL2L1/BSG/DAG1/CHMP6/CIITA/EXOC7/SLC52A2/IFITM1/PLSCR1/HMGB1/PPIA/CD55/SRC/DPP4/WWP2/CR1/TRIM26/ITGB3/ITCH 66
GO:0043534 blood vessel endothelial cell migration 48/3662 123/15509 9.40208e-05 0.000607019 0.000365051 ATP2B4/RHOA/FGFR1/ANGPT2/ABL1/PDGFB/MYH9/CD40/PRKD2/TGFB1/HSPB1/GADD45A/PTK2B/NR4A1/ID1/STAT5A/KDR/APOE/THBS1/CYP1B1/FGF2/EPHA2/SLIT2/PLK2/NOTCH1/ITGB1/VEGFC/PRKCA/NOS3/EFNA1/CIB1/CLN3/HMGB1/CSNK2B/TNF/TMSB4X/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/AKT3 48
GO:0045471 response to ethanol 48/3662 123/15509 9.40208e-05 0.000607019 0.000365051 BAD/BAK1/FGFR2/RHOA/ST6GAL1/OPRK1/OXCT1/SLC23A2/HAMP/GATA3/CSF3/RPS6KB1/CCND1/DNMT3A/CRHR1/PTK2B/CAT/CDO1/CYP2E1/RARA/PRKAA1/ACTR2/IGF1R/TNFRSF11A/SOD1/ALAD/VCAM1/TP53INP1/CYBB/CDK1/FOS/MGMT/CD14/PRKCE/LEP/GRIN1/TYMS/NQO1/ADIPOQ/RPL10A/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 48
GO:0097237 cellular response to toxic substance 48/3662 123/15509 9.40208e-05 0.000607019 0.000365051 MPO/PTGS1/BMP7/GSR/PARK7/PRDX1/PRDX6/MTARC2/ABCG2/UBIAD1/CAT/APOE/PXDN/SESN2/GSTM1/CD36/SOD1/GSTO1/FANCC/FABP1/ALB/NOS3/TP53INP1/GPX4/NXN/PRDX2/NQO1/PRKN/TXNRD1/SELENOT/TNF/TNF/GPX3/LTC4S/HBE1/HBD/TNF/TNF/TNF/TNF/TNF/TNF/HBB/HP/SRXN1/TPO/GSTT1/LTC4S 48
GO:0002204 somatic recombination of immunoglobulin genes involved in immune response 24/3662 49/15509 9.43142e-05 0.000607019 0.000365051 PARP3/FOXP3/TBX21/MLH1/PTPRC/MSH2/CD40/CD40LG/NBN/IL27RA/TGFB1/EXOSC3/NSD2/AICDA/IL4/BCL6/SHLD2/NDFIP1/IL10/SLC15A4/TNFSF13/LIG4/CD28/PTPRC 24
GO:0002208 somatic diversification of immunoglobulins involved in immune response 24/3662 49/15509 9.43142e-05 0.000607019 0.000365051 PARP3/FOXP3/TBX21/MLH1/PTPRC/MSH2/CD40/CD40LG/NBN/IL27RA/TGFB1/EXOSC3/NSD2/AICDA/IL4/BCL6/SHLD2/NDFIP1/IL10/SLC15A4/TNFSF13/LIG4/CD28/PTPRC 24
GO:0045190 isotype switching 24/3662 49/15509 9.43142e-05 0.000607019 0.000365051 PARP3/FOXP3/TBX21/MLH1/PTPRC/MSH2/CD40/CD40LG/NBN/IL27RA/TGFB1/EXOSC3/NSD2/AICDA/IL4/BCL6/SHLD2/NDFIP1/IL10/SLC15A4/TNFSF13/LIG4/CD28/PTPRC 24
GO:0008406 gonad development 73/3662 207/15509 9.45425e-05 0.000607857 0.000365555 HOXA11/HSPA5/ARID4B/MSH4/HOXA9/LRP2/PGR/ATRX/BAX/MMP2/ESR1/MSH2/GATA1/PCYT1B/SFRP1/CASP2/TGFBR1/GATA3/CCND1/PDGFRB/WNT5A/IL1A/SDC1/FOXO3/EIF2B2/TNFSF10/INHBA/MEA1/EIF2S2/KDR/SOX15/BCL2L2/RARA/HSD17B4/PDGFRA/NKX2-1/CYP19A1/CYP1B1/BRCA2/ARRB2/SMAD4/SOD1/RAB13/REN/SLIT2/GAS2/ARID5B/DHX37/BCL2L11/ADAMTS1/MMP14/KIT/WNT4/H3-3A/INHBB/CASP3/TLR3/GDF9/NOS3/ZFPM2/BCL2L1/CEBPB/STAT5B/LEP/FZD4/A2M/SLIT3/ZP3/AKR1C3/SRC/NTRK1/FANCG/HOXA10 73
GO:1902903 regulation of supramolecular fiber organization 109/3662 334/15509 9.46686e-05 0.000608038 0.000365663 SCIN/SPAST/CYFIP2/RHOA/NAV3/ROCK1/SPTB/CDC42/WDR1/ARHGEF10L/ADD2/ACTN2/ADD1/TPX2/PXN/ABL1/HCK/COTL1/PYCARD/TJP1/SFRP1/ARHGEF10/MTPN/MET/TGFBR1/CXCL12/CSF3/RANGRF/CRYAB/HSPA8/ARPC3/PFDN1/DBN1/PARK7/CAPZA1/STMN1/CLU/PTK2B/IAPP/PFDN5/EML2/DSTN/ID1/CCR7/CDC42EP1/APOE/COLGALT1/ARPC1B/PPFIA1/WASF3/PSRC1/APC/DBNL/CCL21/NUMA1/RDX/ABI2/RB1/SLAIN1/BBS4/TBCD/SMAD4/APP/SLIT2/PIK3R1/ARHGAP18/C9orf72/GSN/CDC42EP2/PLEKHH2/DMTN/ARHGAP35/SPTBN4/ALOX15/WNT4/ARPC5/ANKRD23/CDC42EP3/SPTA1/PRKCD/ARFIP1/RICTOR/TTC8/S1PR1/PRKCE/CCL11/SPTBN2/CDK5R1/FLII/GRB2/PAK2/CIB1/INPP5J/PRKN/DRG1/NF2/CD47/GMFB/SPTAN1/MTOR/IQANK1/PFDN6/TMSB4X/PDXP/ARPC1A/TWF2/SHANK3/BRK1/TJP1 109
GO:0001787 natural killer cell proliferation 13/3662 20/15509 9.69791e-05 0.000621589 0.000373813 ELF4/IL12B/PTPN22/IL18/STAT5B/LEP/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 13
GO:0002864 regulation of acute inflammatory response to antigenic stimulus 13/3662 20/15509 9.69791e-05 0.000621589 0.000373813 BTK/FCGR2B/PARK7/C3/CCR7/ZP3/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 13
GO:0014706 striated muscle tissue development 77/3662 221/15509 9.74095e-05 0.000623703 0.000375084 IFRD1/IGF1/PKP2/ERBB3/MAP2K4/FGFR2/SIRT2/CDC42/SIRT6/ACTN2/TP73/LRP2/ZMPSTE24/NOX4/FKBP1A/DSP/ABL1/BMP7/SMAD7/NDRG4/NPRL3/EYA1/TGFB1/HAMP/GSK3A/MTPN/TGFBR1/ENG/BMPR1A/DKK1/MAPK14/BVES/SMAD5/PDGFRB/WNT5A/FHL2/ID2/TNNT2/OBSL1/BMP2/PRMT1/ALDH1A2/SOX15/TNNI3/RARA/MYH11/NOTCH2/PDGFRA/FGF2/ARRB2/SMAD4/NOTCH1/ITGB1/POU4F1/GJA1/SKI/TNNI1/RUNX1/LMNA/MAML1/PDLIM5/TGFBR2/SHH/FRS2/RBPJ/ZFPM2/CDK1/S1PR1/PLEC/CALR/SLC8A1/NKX2-5/NOG/ARID2/MTOR/MYH11/PTEN 77
GO:0061136 regulation of proteasomal protein catabolic process 65/3662 180/15509 0.000101313 0.000648029 0.000389714 OSBPL7/RHBDF1/HFE/PSMC4/RNF14/UFL1/HERPUD1/ATXN3/SIRT2/PRKACA/MKRN2/SIRT6/UBE2K/GSK3B/XPO1/PSMC5/PSME1/HECTD1/BAG6/HSP90AB1/PSMC6/USP14/SMAD7/N4BP1/AXIN1/SGTA/GSK3A/DVL1/USP5/PARK7/CDC20/RAD23B/CLU/USP9X/CBFA2T3/APOE/PSME3/HSPBP1/CSNK1D/GNA12/TLK2/OGT/EIF3H/ALAD/RNF144A/USP25/PSMC2/RYBP/RCHY1/SHH/VCP/PSMC3/BTRC/GLMN/PRKN/USP7/SVIP/BAG6/BAG6/BAG6/BAG6/BAG6/CEBPA/PRKACA/F8A1 65
GO:0014812 muscle cell migration 35/3662 82/15509 0.000102143 0.000652659 0.000392498 IGF1/RHOA/ROCK1/PDGFB/APEX1/NDRG4/PLAT/SERPINE1/BMPR1A/RPS6KB1/MDK/PPARD/PDGFRB/NR4A3/GNA13/LRP1/TLR4/CCN3/SORL1/CYP1B1/SLIT2/GNA12/IGFBP3/ADAMTS1/ARPC5/S100A11/TERT/DDIT3/ADIPOQ/FOXO4/SRC/PARVA/ITGB3/CCL5/CCL5 35
GO:0032526 response to retinoic acid 46/3662 117/15509 0.000105735 0.000673987 0.000405324 CD38/EPHA3/TMEM161A/TIE1/FGFR2/GSK3B/MMP2/DKK1/WNT3/WNT5B/FZD10/PDGFRB/WNT5A/IGFBP2/PTK2B/ALDH1A2/RARA/ABL2/BMP6/AQP3/ZNF35/RARG/LEP/FZD4/WNT7B/GDAP2/IGF2R/RXRB/TNF/TNF/MICB/TNF/MICB/MICB/TNF/TNF/TNF/TNF/MICB/MICB/TNF/MICB/TWF2/OVCA2/WNT3/WNT3 46
GO:0010888 negative regulation of lipid storage 15/3662 25/15509 0.000106024 0.000673987 0.000405324 NFKBIA/PPARD/IL6/ITGAV/LEP/PTPN2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3 15
GO:0042359 vitamin D metabolic process 15/3662 25/15509 0.000106024 0.000673987 0.000405324 SNAI2/LRP2/CYP27B1/IFNG/CYP1A1/CYP3A4/GFI1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:0048143 astrocyte activation 15/3662 25/15509 0.000106024 0.000673987 0.000405324 GRN/IFNG/LRP1/IL1B/NR1D1/IL6/APP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:0051797 regulation of hair follicle development 15/3662 25/15509 0.000106024 0.000673987 0.000405324 CDH3/NGFR/FERMT1/WNT5A/NUMA1/SMAD4/MYSM1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:0051303 establishment of chromosome localization 32/3662 73/15509 0.000108605 0.000689687 0.000414765 CENPQ/NDE1/MLH1/SPAG5/NDC80/PIBF1/SEH1L/CHMP5/ZW10/BIRC5/NUDC/CHMP4B/RAB11A/KAT2B/TTL/BECN1/CHMP1A/CCNB1/PSRC1/CDCA8/NUMA1/CENPE/KIF2C/CENPC/BOD1/GEM/KAT5/CHMP6/AURKB/KIFC1/NDE1/SPICE1 32
GO:0043535 regulation of blood vessel endothelial cell migration 40/3662 98/15509 0.000112367 0.000712844 0.000428692 ATP2B4/RHOA/FGFR1/ANGPT2/ABL1/PDGFB/CD40/PRKD2/TGFB1/HSPB1/GADD45A/STAT5A/KDR/APOE/THBS1/FGF2/EPHA2/PLK2/NOTCH1/VEGFC/PRKCA/NOS3/EFNA1/CIB1/HMGB1/CSNK2B/TNF/TMSB4X/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/AKT3 40
GO:0050890 cognition 98/3662 296/15509 0.000114843 0.000727812 0.000437693 ITGA3/PAFAH1B1/MAPK8IP2/UBA6/RASGRF1/DGCR2/PICALM/ITGA8/OPRK1/ABL1/ADNP/NDRG4/GPI/PTN/PPP3CB/DKK1/RPS6KB1/B3GAT1/MDK/ASIC1/SLC11A2/NEDD9/SOBP/PDE8B/CHST10/PAIP2/EGR2/THRA/MGAT3/APOE/SYT11/EPHB2/KRAS/NGF/ACTR2/BBS4/EIF4A3/APP/ARL6IP5/PLK2/TPBG/EGFR/VLDLR/NTRK2/EIF4EBP2/ITGB1/KIT/CBR3/BTG2/BRSK1/ZNF385A/CAMK2N1/CASP3/ADCY1/CDK5/TTC8/RAG1/SETD5/CX3CR1/RGS14/FOS/CCL11/CEBPB/FOSL1/BDNF/GRIN1/OXTR/PLCB1/NOG/BTBD9/CNTN2/PRKN/CLN3/FZD9/MME/GM2A/SRC/SYNGAP1/NTRK1/TAFA2/GPRASP3/TNF/HLA-DRA/TNF/TNF/HLA-DRA/TNF/TNF/TNF/HLA-DRA/TNF/TNF/HLA-DRA/SHANK3/B2M/HLA-DRA/GPI/PTEN 98
GO:0051961 negative regulation of nervous system development 55/3662 147/15509 0.00011577 0.000732936 0.000440775 TMEM98/IFRD1/CDH1/NTN1/KDM4A/SIRT2/PCM1/BMP7/PTN/BMPR1A/DKK1/WNT3/EFNB3/WNT5A/HES1/SPP1/IL1B/ID1/NR1D1/YWHAH/EPHB2/LRP4/IL6/KIAA0319/SORL1/RB1/DUSP10/CTDSP1/NOTCH1/DPYSL5/SKI/ELAPOR2/CDK5/SEMA4C/SEMA3E/CCL11/F2/NOG/NF2/DCC/SYNGAP1/MBP/GDI1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/B2M/WNT3/WNT3/PTEN 55
GO:0006909 phagocytosis 81/3662 236/15509 0.000116112 0.000734348 0.000441624 ITGAL/BTK/TYROBP/SLC11A1/CYBA/CDC42/FCGR2B/PTPRC/P2RX7/CEBPE/ABL1/MYH9/HCK/SRPX/PYCARD/CSK/MET/CCL2/CORO1C/IFNG/LEPR/LRP1/IL1B/C3/BECN1/RAC2/RARA/SYT11/SFTPD/ARL8B/CD36/TLR4/THBS1/ITGAV/IRF8/SOD1/LYST/IL2RG/GSN/ITGB1/MERTK/APPL1/XKR8/ITGB2/ALOX15/PRKCD/SYK/ARHGAP12/MBL2/NOD2/RHOH/PTK2/ITGAM/CD14/PRKCE/LEP/CALR/ADIPOQ/ADGRB1/PLSCR1/CLN3/HMGB1/PRTN3/CD47/SRC/ELANE/TGM2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/CD302/ITGB3/PECAM1/PTPRC/ELANE/PRTN3 81
GO:0051051 negative regulation of transport 124/3662 390/15509 0.000117117 0.000739949 0.000444992 RHBDF1/CRY1/CD74/TNFRSF1B/EPHA3/ATP9A/KCNH2/ERBB3/SPI1/SP100/VPS35/FCGR2B/DERL2/PICALM/LMAN1/SIRT6/ACTN2/OPRK1/OSM/RANGAP1/MMP9/FERMT1/NDFIP2/CSK/SFRP1/LILRB1/CD33/HAMP/GSK3A/SFRP4/PPP3CB/PPIF/UNC119/CRYAB/PSMD9/ASIC1/IL12B/HES1/PARK7/VAMP8/PKD2/CRHR1/PTK2B/CRY2/INHBA/SEMG1/NUP153/IL1B/PNKD/LIF/APOE/EPO/NDFIP1/SYT11/EPHB2/CD36/MDFIC/SERPINE2/ISCU/CCN3/THBS1/ITGAV/EGF/TMBIM6/CALM2/ARL6IP5/SNX12/NOTCH1/GSTO1/FOXO1/BAG3/GJA1/APPL1/DMTN/STC1/CALM3/PEA15/INHBB/C4orf3/ARFIP1/SHH/NOS3/CDK5/GEM/SLC43A2/PXK/PKIG/LGALS9/PRKCE/LEP/PTPN11/YOD1/OXTR/ADIPOQ/F2R/ANXA2/ADRA2C/PRKN/KCNJ11/PLSCR1/HMGB1/PRTN3/CD47/SVIP/PIM3/WWP2/UBE2J1/GDI1/TNF/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/LILRB1/LILRB1/LILRB1/PRTN3/LILRB1/PTEN 124
GO:0042092 type 2 immune response 18/3662 33/15509 0.000122132 0.000770852 0.000463577 CD74/TBX21/IL4R/ARG2/IL27RA/GATA3/CD81/IL4/BCL6/CD86/ARG1/NDFIP1/RARA/IL6/HLX/IL10/IL18/NOD2 18
GO:0030010 establishment of cell polarity 51/3662 134/15509 0.000122597 0.000772996 0.000464866 PAFAH1B1/SDCCAG8/RHOA/ROCK1/CDC42/MARK2/FBXW11/NDE1/LLGL2/SPAG5/NDC80/GSK3B/RAB10/ZW10/NSFL1C/HSP90AB1/ABL1/MYH9/FERMT1/LAMA1/GATA3/CYTH1/AMOTL2/WNT5A/HES1/PTK2B/CCR7/PLEKHG3/FOXJ1/FLOT2/SPRY2/CCL21/NUMA1/IGF1R/ABL2/SNX27/MSN/GSN/PARD3/ITGB1/GJA1/BRSK1/RICTOR/SHH/TTC8/WEE1/PTK2/CCL19/KAT5/BRSK2/NDE1 51
GO:0051100 negative regulation of binding 57/3662 154/15509 0.000123516 0.000777998 0.000467874 KDM1A/HFE/SP100/ROCK1/ACTB/RAP1GAP/GSK3B/BAX/TFIP11/CYP2D6/PDGFB/NFKBIA/ADNP/GATA1/TLE5/DVL1/MAPK8/DKK1/ITGA4/PARK7/IFIT2/TEX14/CDKN1A/ID1/PIN1/PER2/IL10/SORL1/TDG/TMBIM6/ARRB2/EIF4A3/C9orf72/HMGA2/PEX19/DISC1/PRKCD/C4orf3/GOLGA2/ADRB2/ATP2A2/DDIT3/JUN/CTNNBIP1/AURKB/ADIPOQ/RGMA/NOG/SUMO3/TMSB4X/CPNE1/CYP2D6/B2M/CYP2D6/CYP2D6/CYP2D6/CYP2D6 57
GO:0070884 regulation of calcineurin-NFAT signaling cascade 22/3662 44/15509 0.000124415 0.000782868 0.000470803 PTBP1/IGF1/ATP2B4/ERBB3/GSK3B/NFAT5/PPP3CB/FHL2/DYRK2/SPPL3/CHP2/CIB1/MTOR/TNF/TNF/STIMATE/TNF/TNF/TNF/TNF/TNF/TNF 22
GO:0045927 positive regulation of growth 80/3662 233/15509 0.000125741 0.000790366 0.000475312 CD38/PAFAH1B1/IGF1/CYBA/NTN1/FGFR2/RHOA/CDC42/DERL2/SLC23A2/KDM2B/ADNP/SMAD7/SFRP1/IL7/DDX49/HAMP/MTPN/BRAT1/TGFBR1/CXCL12/BMPR1A/WNT3/RPS6KB1/ZPR1/EIF4G2/PPARD/MAPK14/HBEGF/DBN1/FN1/GPAM/SERP1/PTK2B/CXCR4/SOX15/NGF/DBNL/HLX/NCBP1/FGF2/BBS4/CRABP2/SYT2/EGFR/NOTCH1/POU4F2/MMP14/SPTBN4/DISC1/H3-3A/TGFBR2/RICTOR/FXN/RBPJ/CDKN2AIP/ZFPM2/CDK1/LPAR3/SLC25A33/STAT5B/LEP/RAG2/BDNF/CDH4/F2/PLCB1/CSF1/POU3F2/CIB1/PRKN/PRR5/TEAD1/ZP3/MTOR/GDI1/TWF2/GH1/WNT3/WNT3 80
GO:0007179 transforming growth factor beta receptor signaling pathway 67/3662 188/15509 0.000125862 0.000790366 0.000475312 ITGA3/HSPA5/ARID4B/HIPK2/SPI1/ITGA8/FKBP1A/PXN/GLG1/HSP90AB1/FERMT1/SMAD7/RBBP7/AXIN1/TGFB1/TGFBR1/ENG/BMPR1A/ZMIZ1/LPXN/FOLR1/ZNF451/SMAD5/HDAC1/FMOD/USP9X/BMP2/ID1/PIN1/TWSG1/CDKN1C/GDF15/MEN1/SPRY2/NKX2-1/THBS1/SMAD6/TET1/FBN2/FURIN/ARRB2/SMAD4/PARP1/OGT/ZEB1/NODAL/APPL1/SKI/RBBP4/TGFBR2/SAP30/GDF9/HTRA1/ADAM9/PTK2/ZEB2/FOS/SMAD2/EID2/JUN/ZNF703/BCL9L/SRC/TRIM33/SLC2A10/SPRED2/CDKN1C 67
GO:0030889 negative regulation of B cell proliferation 12/3662 18/15509 0.00012721 0.000795607 0.000478464 BTK/TYROBP/FCGR2B/PKN1/IL10/TNFRSF21/CTLA4/CASP3/INPP5D/TNFRSF13B/INPP5D/PTEN 12
GO:0042772 DNA damage response, signal transduction resulting in transcription 12/3662 18/15509 0.00012721 0.000795607 0.000478464 HIPK2/SP100/RPS6KA6/ZNHIT1/FOXM1/CDKN1A/BRCA2/ZNF385A/RPL26/KAT5/CHEK2/MUC1 12
GO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation 12/3662 18/15509 0.00012721 0.000795607 0.000478464 RUNX3/FOXP3/CBFB/TBX21/IL4R/SMAD7/JAK3/IL4/BCL6/HLX/RUNX1/HMGB1 12
GO:0051315 attachment of mitotic spindle microtubules to kinetochore 12/3662 18/15509 0.00012721 0.000795607 0.000478464 NDC80/SEH1L/BIRC5/KAT2B/BECN1/CDCA8/CENPE/KIF2C/CENPC/BOD1/KAT5/AURKB 12
GO:0072006 nephron development 50/3662 131/15509 0.000130926 0.000818026 0.000491947 HOXA11/ITGA3/PROM1/SEC61A1/NOTCH3/ANGPT2/PDGFB/BMP7/EYA1/TMEM59L/GATA3/ACTA2/PDGFRB/HES1/STAT1/PKD2/TEK/EGR1/NUP85/BMP2/LIF/PODXL/FOXJ1/LAMA5/NOTCH2/PDGFRA/AHI1/EDNRB/PLCE1/FGF2/ENPEP/GREB1L/SMAD4/ADAMTS16/KLHL3/NOTCH1/IL6R/WNT4/HEYL/SHH/LAMB2/CTNNBIP1/ADIPOQ/NOG/PBX1/MAGI2/WNT7B/ITGB3/PECAM1/CD24 50
GO:0008380 RNA splicing 121/3662 380/15509 0.000131353 0.000819865 0.000493052 KDM1A/PTBP1/CLK1/ZCCHC8/THOC3/SNRNP40/DDX20/DAZAP1/FAM50A/MBNL3/DDX1/ATXN7L3/RTRAF/SF3B2/FUS/RBM41/HNRNPC/CWF19L1/CIRBP/SNRPD3/TFIP11/SNU13/RBFOX2/ACIN1/PNN/PRPF6/ESRP1/SNRNP70/YJU2/CASC3/C1QBP/DDX5/EFTUD2/ZPR1/HSPA8/SRSF9/FAM172A/PPP2CA/KAT2B/NCL/SF3B1/SRSF7/SRSF4/PRPF3/PTBP2/PRDX6/PTBP3/NRDE2/TARDBP/COIL/SMU1/SNRPC/AHNAK/RNF113A/HNRNPR/RALY/RBM42/PRMT1/SCAF1/HNRNPH2/AAR2/GRSF1/PRMT7/RBM17/SRPK2/HNRNPA1/TAF5L/SRSF1/PRPF4/NCBP1/DBR1/CIR1/SCAF11/SNRPF/TMBIM6/DHX38/EIF4A3/SF3B4/SNRPG/PIK3R1/WTAP/LUC7L2/NONO/RBMX/TRPT1/CWC15/MBNL1/CWC27/TAF6L/RBM15/THOC7/CCNL1/FASTK/RPUSD4/SNRPD1/CDK12/SRRM2/SNRNP48/USP39/HNRNPH1/ZRSR2/HNRNPA3/TADA3/SMN1/CLP1/LARP7/PUS1/ERN1/NPM1/RBM10/RNPC3/TRRAP/UBL5/LSM2/CCNL2/RBM15B/SRSF8/RBM8A/SRSF1/PRPF8/TAF15 121
GO:2000117 negative regulation of cysteine-type endopeptidase activity 36/3662 86/15509 0.000132318 0.00082506 0.000496176 LTF/HGF/BIRC3/CD44/BIRC5/MMP9/BIRC7/GPI/DNAJB6/CRYAB/PARK7/NR4A1/MICAL1/THBS1/ARRB2/CAST/FABP1/INTS1/RAG1/SERPINB9/TRIAP1/PAK2/SRC/TNF/TNF/MAGEA3/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/NAIP/NAIP/GPI 36
GO:2000810 regulation of bicellular tight junction assembly 16/3662 28/15509 0.000139957 0.000871813 0.000524293 SNAI2/ROCK1/PRKACA/TJP1/IL17A/EPHA2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TJP1/PRKACA 16
GO:0043516 regulation of DNA damage response, signal transduction by p53 class mediator 19/3662 36/15509 0.000142705 0.000886257 0.00053298 KDM1A/SNAI2/CD74/CD44/ZMPSTE24/YJU2/ZNHIT1/DDX5/SOX4/EEF1E1/PMAIP1/DYRK3/ZNF385A/RPL26/NPM1/PTTG1IP/KMT5A/SPRED2/MIF 19
GO:0098581 detection of external biotic stimulus 19/3662 36/15509 0.000142705 0.000886257 0.00053298 NOD1/TLR4/NOD2/HLA-B/HLA-A/HLA-A/HLA-B/HLA-A/HLA-A/HLA-B/HLA-A/HLA-B/HLA-A/HLA-A/HLA-B/HLA-A/NAIP/NAIP/NAIP 19
GO:1903749 positive regulation of establishment of protein localization to mitochondrion 19/3662 36/15509 0.000142705 0.000886257 0.00053298 CSNK2A2/SH3GLB1/GZMB/PDCD5/GSK3A/MAPK8/RAC2/PRKAA1/NMT1/SAE1/BAP1/ATG13/UBE2L3/UBL5/HSPA1L/HSPA1L/HSPA1L/HSPA1L/HSPA1L 19
GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I 14/3662 23/15509 0.000145818 0.000904687 0.000544063 TAP1/TAP1/HLA-A/HLA-A/HLA-A/TAP1/HLA-A/TAP1/HLA-A/TAP1/HLA-A/TAP1/HLA-A/HLA-A 14
GO:0060627 regulation of vesicle-mediated transport 149/3662 484/15509 0.000146563 0.0009084 0.000546296 SELE/BTK/HFE/CD22/SLC11A1/GAB2/AP2S1/EPHA3/C12orf4/CYBA/ATP9A/SPI1/ROCK1/CDC42/FCGR2B/PICALM/NSF/STXBP2/IL4R/ACTN2/PTPRC/GSK3B/RAB10/RAPGEF4/ABL1/HCK/GATA1/NDRG4/TSC2/PYCARD/CSK/RAB11A/EHD4/LILRB1/TFR2/SERPINE1/SFRP4/DVL1/PPP3CB/DKK1/SEPTIN4/CCL2/RAB5C/UNC119/IFNG/BVES/IL4/WNT5A/SNX4/SNX17/SDC1/RIMS3/VAMP8/CLU/LRP1/ACSL3/IL1B/C3/RAC2/APOE/PRKAA1/SYT11/CPLANE2/SFTPD/CD36/AHI1/MICAL1/STXBP1/CCL21/SORL1/RDX/PREPL/ITGAV/EGF/ARRB2/SOD1/ABL2/RAB13/SNAPIN/SYT2/CPLX2/MSN/SNX12/IL2RG/NOTCH1/BICD1/MERTK/APPL1/LDLRAP1/CALM3/ITGB2/AP2M1/ALOX15/ARFIP1/ADCY1/CDK5/SYK/TRPV6/MBL2/NOD2/SEPTIN2/LGALS9/PTAFR/ITGAM/PDCD6IP/CD14/FGG/FGA/CCL19/ATP2A2/CDK5R1/CALR/MAPK15/ADIPOQ/CACNB4/ANXA2/BTBD9/PRKN/HGS/MAGI2/USP7/PLSCR1/ZP3/CLN3/HMGB1/PRTN3/CACNA1H/CD47/PGAP1/SRC/TGM2/TNF/CD177/TNF/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3/PTPRC/B2M/LILRB1/LILRB1/TRPV6/LILRB1/PRTN3/LILRB1 149
GO:0046209 nitric oxide metabolic process 32/3662 74/15509 0.000148427 0.00091903 0.000552689 CPS1/ATP2B4/ARG2/HSP90AB1/CYB5R3/ACP5/IFNG/MTARC2/PKD2/CLU/PTK2B/IL1B/ASS1/CD36/IL10/TLR4/CYP1B1/DDAH1/NOS3/CX3CR1/NQO1/TRPV1/CD47/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HBB 32
GO:0044706 multi-multicellular organism process 67/3662 189/15509 0.000150606 0.000930194 0.000559403 CD38/ITGA3/TAC1/HEXB/PRDM1/VMP1/EPN1/DAZAP1/FBLN1/PGR/OVGP1/TMED2/MMP2/ESR1/ANGPT2/MMP9/SYDE1/KLF1/PTN/AMBP/C1QBP/CALCA/CYP27B1/VDR/PPARD/IGFBP2/ASH1L/SLC2A1/ARG1/SPP1/PGF/CRHR1/RECK/SEMG1/IL1B/FOSB/LIF/EPO/RARA/MEN1/SERPINE2/CYP1A1/SOD1/PARP1/CORIN/GJA1/NODAL/STC1/WNT4/CAPN2/H3-3A/TGFBR2/LGALS9/PTAFR/FOS/BSG/SLC19A1/STAT5B/LEP/FOSL1/CALR/OXTR/PAPPA/YTHDF3/EPOR/ITGB3/LOC102724560 67
GO:0045453 bone resorption 26/3662 56/15509 0.00015068 0.000930194 0.000559403 CD38/NOX4/P2RX7/ACP5/CSK/IL7/HAMP/CALCA/TNFAIP3/SPP1/PTK2B/IAPP/IL6/DEF8/TNFRSF11A/PRKCA/TNFRSF11B/SYK/INPP5D/ADRB2/S1PR1/GPR137/CSF1R/SRC/ITGB3/INPP5D 26
GO:0046824 positive regulation of nucleocytoplasmic transport 26/3662 56/15509 0.00015068 0.000930194 0.000559403 CDH1/IPO5/HYAL2/PRKACA/SIRT6/GSK3B/MAVS/HSP90AB1/TGFB1/ZPR1/IFNG/MAPK14/NRDE2/TARDBP/IL1B/XPO4/ANP32B/PIK3R1/TCF7L2/BAG3/PRKCD/SHH/CHP2/CDK1/LEP/PRKACA 26
GO:0031060 regulation of histone methylation 31/3662 71/15509 0.000151171 0.000932296 0.000560666 KDM1A/KMT2E/PAF1/AASS/KDM4A/ATRX/DNMT3B/SMARCB1/GATA3/MACROH2A1/KDM3A/MYB/PHF19/PRDM12/DNMT1/TET1/SKIC8/SMAD4/OGT/NSD3/SMARCA5/RNF20/LMNA/GFI1/PYGO2/NSD1/NNMT/HCFC1/PAX5/WDR5/SMARCB1 31
GO:2000756 regulation of peptidyl-lysine acetylation 30/3662 68/15509 0.000153162 0.000942318 0.000566694 NFYA/KMT2E/BAZ1B/SNAI2/FOXP3/NFYC/SPI1/ZMPSTE24/SMARCB1/GATA3/ZNF451/SF3B1/PARK7/SOX4/DEK/LIF/PRKAA1/MYBBP1A/WBP2/SMAD4/SMARCA5/CTBP1/PYGO2/BRD7/SETD5/TAF7/MUC1/NOC2L/SMARCB1/TADA2A 30
GO:0051205 protein insertion into membrane 27/3662 59/15509 0.000153176 0.000942318 0.000566694 AGK/SEC61A1/BAX/BAG6/TIMM13/SAMM50/GZMB/TIMM9/UBL4A/SGTA/PDCD5/MAPK8/CCDC47/EMC3/EMC4/TIMM10B/NMT1/EGFR/TIMM8B/EMC10/TOMM20/TOMM5/BAG6/BAG6/BAG6/BAG6/BAG6 27
GO:0010595 positive regulation of endothelial cell migration 39/3662 96/15509 0.000153252 0.000942318 0.000566694 GRN/FLT4/FGFR1/ABL1/PDGFB/CD40/GPI/PRKD2/TGFB1/PIK3CG/MET/HSPB1/GATA3/SMOC2/WNT5A/NRP2/TEK/PTK2B/RRAS/STAT5A/KDR/THBS1/FGF2/EGF/RHOB/PLK2/VEGFC/PRKCA/EMC10/NOS3/CALR/CIB1/HMGB1/TMSB4X/ZNF580/PDCD6/ITGB3/AKT3/GPI 39
GO:0014910 regulation of smooth muscle cell migration 29/3662 65/15509 0.00015426 0.000946985 0.0005695 IGF1/RHOA/PDGFB/APEX1/NDRG4/SERPINE1/BMPR1A/RPS6KB1/MDK/PPARD/PDGFRB/NR4A3/GNA13/LRP1/TLR4/SORL1/CYP1B1/SLIT2/GNA12/IGFBP3/ADAMTS1/S100A11/TERT/ADIPOQ/FOXO4/SRC/ITGB3/CCL5/CCL5 29
GO:0035306 positive regulation of dephosphorylation 28/3662 62/15509 0.000154317 0.000946985 0.0005695 PTBP1/ROCK1/PTPRC/PPP1R15A/HSP90AB1/PPP1R16B/TGFB1/CD33/IFNG/PPP2R5D/PDGFRB/PTPA/BMP2/PIN1/CALM2/GNA12/SPPL3/PPP1R15B/CALM3/PRKCD/NSMF/CHP2/ANKLE2/MAGI2/PPIA/SRC/MTOR/PTPRC 28
GO:0042692 muscle cell differentiation 111/3662 345/15509 0.000155371 0.000952509 0.000572822 KDM1A/IFRD1/SPAG9/CD9/PTBP1/IGF1/BARX2/MAP2K4/FGFR2/WDR1/IL4R/SIRT6/ACTN2/ITGA8/ZMPSTE24/NOX4/XBP1/PDGFB/MYH9/NFATC2/LAMA1/PIEZO1/OLFM2/TGFB1/HAMP/GSK3A/MTPN/ZNHIT1/EZH2/ENG/PPP3CB/BMPR1A/DKK1/CNTNAP1/CD81/WNT5B/MAPK14/BVES/IL4/PDGFRB/HES1/FHL2/ID2/SDC1/BCL9/TNNT2/MORF4L2/OBSL1/BMP2/GDF15/DNMT1/SYNE1/RARA/MYH11/KRAS/PDGFRA/AKIRIN2/LAMC1/EDNRB/CCN3/MYOF/TARBP2/RB1/ARRB2/SMAD4/SYPL2/KCNH1/ANK2/NOTCH1/ZEB1/ITGB1/UCHL1/MMP14/KIT/SKI/LMNA/MAML1/SELENON/WNT4/CAPN2/H3-3A/PDLIM5/ANKRD23/CASP3/SHH/GPER1/FRS2/RBPJ/SEMA4C/CDK1/CDH2/LAMB2/ATP2A2/GLMN/BDNF/FLII/PLEC/CALR/ADGRB1/CACNB4/SLC8A1/NKX2-5/SETD3/FOXO4/STAC3/P2RX2/CACNA1H/MRTFA/MTOR/ZBED6/MYH11 111
GO:0048871 multicellular organismal homeostasis 151/3662 492/15509 0.000155715 0.000953679 0.000573526 CD38/KDM1A/USH1C/ADIPOR2/PROM1/HFE/LTF/SLC11A1/CDH3/HYAL2/TFE3/PRKACA/ACADVL/TP63/ACTB/IL4R/SIRT6/NOX4/ACHE/BAX/P2RX7/LYZ/SCD/CHMP4B/GATA1/ACP5/CSK/TJP1/IL7/HAMP/MET/HSPB1/CDH23/MAP2K6/CALCA/SLC11A2/RHAG/IL17A/IL4/NPHP3/IL1A/KDM3A/PASK/EPAS1/AMPD2/LEPR/MFN2/SLC2A1/PRDX1/STMN1/TNFAIP3/SPP1/NR4A3/EGR1/PTK2B/IAPP/CXCR4/USP45/IL1B/ID1/THRA/NR1D1/KDR/PER2/PRKAA1/SFTPD/KRAS/APC/CD36/LAMC1/EDNRB/IL6/TLR4/IRF4/COL2A1/RB1/IGF1R/BBS4/DEF8/TNFRSF11A/SOD1/FLG/PDGFC/OGT/UGCG/LCN2/NOTCH1/CDHR1/ITGB1/IL18/FOXO1/GJA1/BMP6/PRKCA/DRAM2/CLDN12/ADIPOR1/OMA1/ALB/BAP1/TNFRSF11B/NOS3/SYK/AQP3/NOD2/ABCA3/RBPJ/NKIRAS2/INPP5D/ADRB2/S1PR1/ALK/KSR2/CEBPB/IQCB1/GPR137/LEP/DDIT3/PLEC/PTPN11/BBS10/OXTR/ADIPOQ/F2R/CSF1R/BTBD9/CSF1/TRPV1/SRC/SLC22A5/NKIRAS1/MBP/GIGYF2/TNF/TNF/EBF2/TNF/TNF/TNF/TNF/TNF/TNF/PGAM5/ITGB3/PECAM1/B2M/AKT3/TJP1/INPP5D/SQSTM1/PRKACA 151
GO:0045137 development of primary sexual characteristics 73/3662 210/15509 0.000157952 0.000966421 0.000581189 HOXA11/HSPA5/ARID4B/MSH4/HOXA9/LRP2/PGR/ATRX/BAX/MMP2/ESR1/MSH2/GATA1/PCYT1B/SFRP1/CASP2/TGFBR1/GATA3/CCND1/PDGFRB/WNT5A/IL1A/SDC1/FOXO3/EIF2B2/TNFSF10/INHBA/MEA1/EIF2S2/KDR/SOX15/BCL2L2/RARA/HSD17B4/PDGFRA/NKX2-1/CYP19A1/CYP1B1/BRCA2/ARRB2/SMAD4/SOD1/RAB13/REN/SLIT2/GAS2/ARID5B/DHX37/BCL2L11/ADAMTS1/MMP14/KIT/WNT4/H3-3A/INHBB/CASP3/TLR3/GDF9/NOS3/ZFPM2/BCL2L1/CEBPB/STAT5B/LEP/FZD4/A2M/SLIT3/ZP3/AKR1C3/SRC/NTRK1/FANCG/HOXA10 73
GO:0072089 stem cell proliferation 43/3662 109/15509 0.000159862 0.000977146 0.000587639 KDM1A/SNAI2/EIF2AK2/TP63/SIRT6/FBLN1/XRCC5/PTPRC/MECOM/ABCB1/FERMT1/ERCC2/CCNE1/RNF43/WNT3/WNT5A/PRRX1/IRF6/RUNX2/KDR/FGF2/ETV6/BRCA2/NOTCH1/HMGA2/VEGFC/GJA1/RUNX1/TGFBR2/TERT/SHH/RBPJ/RARG/LIG4/PBX1/ZFP36L1/NF2/WNT7B/CEBPA/YJEFN3/PTPRC/WNT3/WNT3 43
GO:0032435 negative regulation of proteasomal ubiquitin-dependent protein catabolic process 20/3662 39/15509 0.000160968 0.000982937 0.000591121 HFE/BAG6/HSP90AB1/USP14/N4BP1/SGTA/PARK7/USP9X/TLK2/OGT/EIF3H/RYBP/SHH/USP7/SVIP/BAG6/BAG6/BAG6/BAG6/BAG6 20
GO:0001780 neutrophil homeostasis 11/3662 16/15509 0.000163612 0.000990788 0.000595843 BTK/MTHFD1/SH2B3/MPL/IL6/MERTK/XKR8/CXCR2/CSF1/PDE4B/HMGB1 11
GO:0002424 T cell mediated immune response to tumor cell 11/3662 16/15509 0.000163612 0.000990788 0.000595843 AHR/MR1/HMGB1/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A 11
GO:0020027 hemoglobin metabolic process 11/3662 16/15509 0.000163612 0.000990788 0.000595843 ALAS1/HPX/CAT/INHBA/PRMT1/EPO/ABCB10/SLC25A37/ALAS2/EPB42/AHSP 11
GO:0031620 regulation of fever generation 11/3662 16/15509 0.000163612 0.000990788 0.000595843 IL1B/EDNRB/TNFRSF11A/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 11
GO:0046643 regulation of gamma-delta T cell activation 11/3662 16/15509 0.000163612 0.000990788 0.000595843 PTPRC/LILRB1/SOX4/SYK/NOD2/STAT5B/PTPRC/LILRB1/LILRB1/LILRB1/LILRB1 11
GO:0071635 negative regulation of transforming growth factor beta production 11/3662 16/15509 0.000163612 0.000990788 0.000595843 TYROBP/CDH3/HSP90AB1/LILRB1/FN1/FURIN/CD24/LILRB1/LILRB1/LILRB1/LILRB1 11
GO:0097048 dendritic cell apoptotic process 11/3662 16/15509 0.000163612 0.000990788 0.000595843 LILRB1/CXCL12/CCR7/CCL21/LGALS9/BCL2L1/CCL19/LILRB1/LILRB1/LILRB1/LILRB1 11
GO:2000668 regulation of dendritic cell apoptotic process 11/3662 16/15509 0.000163612 0.000990788 0.000595843 LILRB1/CXCL12/CCR7/CCL21/LGALS9/BCL2L1/CCL19/LILRB1/LILRB1/LILRB1/LILRB1 11
GO:0008064 regulation of actin polymerization or depolymerization 53/3662 142/15509 0.000164012 0.000990788 0.000595843 SCIN/CYFIP2/RHOA/SPTB/WDR1/ADD2/ACTN2/ADD1/HCK/COTL1/PYCARD/MTPN/CXCL12/CSF3/ARPC3/DBN1/CAPZA1/PTK2B/DSTN/CCR7/CDC42EP1/ARPC1B/DBNL/CCL21/RDX/BBS4/SLIT2/ARHGAP18/GSN/CDC42EP2/PLEKHH2/DMTN/ARHGAP35/SPTBN4/ALOX15/ARPC5/CDC42EP3/SPTA1/PRKCD/RICTOR/PRKCE/CCL11/SPTBN2/FLII/GRB2/SPTAN1/MTOR/IQANK1/TMSB4X/PDXP/ARPC1A/TWF2/BRK1 53
GO:0032147 activation of protein kinase activity 53/3662 142/15509 0.000164012 0.000990788 0.000595843 IGF1/SLC11A1/MARK2/TRAF4/PIBF1/TPX2/ABL1/PDGFB/ADNP/AXIN1/AREG/CALCA/HBEGF/IL12B/IL4/CD86/WNT5A/MOB1A/PARK7/TNFRSF10B/PTK2B/EPO/CHI3L1/BORA/EGF/PDGFC/EGFR/IL18/IL6R/DBF4B/TGFBR2/PRKCD/TLR3/ADRB2/GPRC5C/MOB3A/LEP/CDK5R1/ADRA2C/IRAK1/SOCS1/PPIA/SRC/MTOR/DAXX/DAXX/DAXX/DAXX/DAXX/ITGB3/GH1/CCL5/CCL5 53
GO:0050768 negative regulation of neurogenesis 53/3662 142/15509 0.000164012 0.000990788 0.000595843 TMEM98/IFRD1/CDH1/NTN1/KDM4A/SIRT2/PCM1/BMP7/PTN/BMPR1A/WNT3/EFNB3/WNT5A/HES1/SPP1/IL1B/ID1/NR1D1/YWHAH/EPHB2/LRP4/IL6/KIAA0319/SORL1/RB1/DUSP10/CTDSP1/NOTCH1/DPYSL5/SKI/CDK5/SEMA4C/SEMA3E/CCL11/F2/NOG/NF2/DCC/SYNGAP1/MBP/GDI1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/B2M/WNT3/WNT3/PTEN 53
GO:0052547 regulation of peptidase activity 121/3662 382/15509 0.00016748 0.00101075 0.000607849 BAD/CASP10/LTF/HGF/BIRC3/FAS/CD44/BAK1/GRN/CYFIP2/NGFR/RHOA/ROCK1/PSME4/TP63/PICALM/FBLN1/BAX/PEBP1/BIRC5/PSME1/PSMA3/MMP9/BIRC7/USP14/MEFV/PYCARD/PDCD5/GPI/TFPI2/DNAJB6/NOD1/CASP2/SERPINE1/AMBP/CRYAB/PERP/FN1/HSPE1/PARK7/HDAC1/FASLG/SERPINC1/TNFSF10/RECK/NR4A1/LRP1/SEMG1/C3/SPINK2/ADRM1/PSME3/NGF/AKIRIN2/MICAL1/SERPINE2/TANK/ANP32B/MTCH1/SORL1/THBS1/BCL2L10/FURIN/ARRB2/PMAIP1/APP/CCN1/ARL6IP5/GSN/SERPINH1/CRIM1/BCL2L11/CAST/NODAL/FABP1/GPER1/INTS1/SYK/VCP/RAG1/FADD/LGALS9/PRELID1/EFNA1/ANTXR1/MGMT/SERPINB9/TRIAP1/EIF2AK3/A2M/GRIN1/SVBP/PAK2/F2R/ANXA2/CARD9/HMGB1/SPOCK3/DAPK1/SRC/MAP3K5/SSPOP/MBP/CR1/TNF/PSENEN/TNF/FIS1/MAGEA3/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/PDCD6/NAIP/CRIM1/NAIP/GPI 121
GO:0090287 regulation of cellular response to growth factor stimulus 93/3662 281/15509 0.000171675 0.00103506 0.000622467 ITGA3/DCN/HSPA5/ARID4B/CYFIP2/ATP2B4/NGFR/HIPK2/FGFR1/ITGA8/LRP2/FKBP1A/GLG1/HSP90AB1/ABL1/FERMT1/SMAD7/RBBP7/AXIN1/SFRP1/PRKD2/TGFB1/SFRP4/ENG/GATA3/DKK1/FOLR1/ZNF451/SMOC2/IL12B/IL4/WNT5A/HES1/HDAC1/SFRP5/RUNX2/IL1B/BMP2/PIN1/KDR/TWSG1/CDKN1C/MEN1/NOTCH2/SPRY2/NKX2-1/NUMA1/SORL1/THBS1/SMAD6/TET1/FGF2/FBN2/TOB1/RNF165/SMAD4/CCN1/ARNT/SLIT2/OGT/NOTCH1/ZEB1/VEGFC/CRIM1/HHEX/CXCL13/SKI/RBBP4/WNT4/SAP30/ELAPOR2/HTRA1/RBPJ/ZEB2/FZD4/SMAD2/EID2/FAM20C/RGMA/NOG/ZNF703/PTP4A3/HGS/BCL9L/TMPRSS6/SPRY4/TRIM33/SLC2A10/SPRED2/PDCD6/ITGB3/CDKN1C/CRIM1 93
GO:0070670 response to interleukin-4 17/3662 31/15509 0.000172593 0.00103959 0.000625189 HSPA5/IL4R/HSP90AB1/XBP1/JAK3/GATA3/ARG1/TUBA1B/IL2RG/ALAD/ADAMTS13/IL24/CCL11/STAT5B/PTPN2/SHPK/ADAMTS13 17
GO:2001243 negative regulation of intrinsic apoptotic signaling pathway 36/3662 87/15509 0.000174948 0.00105275 0.000633102 KDM1A/SNAI2/CD74/CD44/HERPUD1/TMEM161A/XBP1/MMP9/URI1/HSPB1/CREB3/CXCL12/PPIF/PARK7/HDAC1/HELLS/CLU/TRAP1/BCL2L2/EPO/BCL2L10/TMBIM6/NONO/ZNF385A/TRIAP1/BCL2L1/GRINA/PTTG1IP/PRKN/MUC1/NOC2L/PPIA/SRC/NDUFS3/MAGEA3/MIF 36
GO:0070266 necroptotic process 21/3662 42/15509 0.000176597 0.00106164 0.000638452 BIRC3/FAS/DNM1L/PPIF/FASLG/RBCK1/MUTYH/PARP1/OGT/TLR3/FADD/FZD9/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PGAM5 21
GO:0034502 protein localization to chromosome 41/3662 103/15509 0.000178677 0.0010731 0.000645343 IFFO1/CENPQ/PARP3/SPI1/SIRT6/XRCC5/NDC80/ATRX/ZW10/ESR1/MSH2/EZH2/MACROH2A1/SLF2/H2BC11/POT1/MAU2/DKC1/WBP2/PPHLN1/CCT7/KNL1/NABP2/BRCA2/RB1/BOD1/MRNIP/TERT/VCP/CCT2/CDK1/ZWILCH/AURKB/RCC2/SETD2/H4C15/H4C14/H4C12/H4C5/H4C4/TINF2 41
GO:0007548 sex differentiation 85/3662 253/15509 0.00018267 0.00109602 0.000659128 HOXA11/BAK1/HSPA5/ARID4B/MSH4/TP63/HOXA9/LRP2/PGR/ATRX/BAX/MMP2/ESR1/MSH2/GATA1/PCYT1B/SFRP1/CASP2/TGFBR1/GATA3/BMPR1A/CCND1/SMAD5/PDGFRB/WNT5A/IL1A/SDC1/FOXO3/EIF2B2/TNFSF10/INHBA/CNTFR/MEA1/EIF2S2/KDR/SOX15/BCL2L2/RARA/HSD17B4/PDGFRA/NKX2-1/CYP19A1/CYP1B1/BRCA2/GREB1L/ARRB2/SMAD4/SOD1/RAB13/REN/CNOT9/SLIT2/GAS2/ARID5B/DHX37/BCL2L11/BMP6/MERTK/ADAMTS1/MMP14/KIT/WNT4/H3-3A/INHBB/CASP3/TLR3/GDF9/SHH/NOS3/ZFPM2/BCL2L1/CEBPB/STAT5B/LEP/FZD4/A2M/PTPN11/SLIT3/PBX1/ZP3/AKR1C3/SRC/NTRK1/FANCG/HOXA10 85
GO:0048736 appendage development 62/3662 173/15509 0.000184593 0.00110542 0.000664777 HOXA11/BAK1/ALX4/FGFR2/PITX1/TP63/PLXNA2/TULP3/HOXA9/ATRX/BAX/BMP7/RPGRIP1L/LMBR1/BMPR1A/FBXW4/DKK1/WNT3/ZBTB16/KAT2B/WNT5A/PRRX1/HDAC1/IRF6/RECK/SOX4/RUNX2/HOXD9/ALDH1A2/RARA/CPLANE2/NOTCH2/LRP4/TFAP2A/FBN2/COL2A1/RNF165/SMAD4/CRABP2/AFF3/GNA12/NOTCH1/FREM2/MBNL1/BCL2L11/SKI/PITX2/SHH/RARG/NOG/PBX1/ZNF358/PBX2/PBX2/SP9/PBX2/PBX2/PBX2/PBX2/HOXA10/WNT3/WNT3 62
GO:0060173 limb development 62/3662 173/15509 0.000184593 0.00110542 0.000664777 HOXA11/BAK1/ALX4/FGFR2/PITX1/TP63/PLXNA2/TULP3/HOXA9/ATRX/BAX/BMP7/RPGRIP1L/LMBR1/BMPR1A/FBXW4/DKK1/WNT3/ZBTB16/KAT2B/WNT5A/PRRX1/HDAC1/IRF6/RECK/SOX4/RUNX2/HOXD9/ALDH1A2/RARA/CPLANE2/NOTCH2/LRP4/TFAP2A/FBN2/COL2A1/RNF165/SMAD4/CRABP2/AFF3/GNA12/NOTCH1/FREM2/MBNL1/BCL2L11/SKI/PITX2/SHH/RARG/NOG/PBX1/ZNF358/PBX2/PBX2/SP9/PBX2/PBX2/PBX2/PBX2/HOXA10/WNT3/WNT3 62
GO:0072073 kidney epithelium development 48/3662 126/15509 0.000186264 0.00111435 0.000670148 HOXA11/PROM1/FGFR2/ARG2/BMP7/SMAD7/EYA1/SFRP1/TMEM59L/GATA3/SMAD5/HES1/STAT1/SDC1/PKD2/CAT/BMP2/LIF/PODXL/FOXJ1/LAMA5/RARA/NOTCH2/AHI1/EDNRB/SMAD6/FGF2/GREB1L/SMAD4/SLIT2/ADAMTS16/KLHL3/NOTCH1/WNT4/HEYL/SHH/LAMB2/SMAD2/CTNNBIP1/CXCR2/ADIPOQ/NOG/PBX1/MAGI2/WNT7B/KANK2/PECAM1/CD24 48
GO:0030433 ubiquitin-dependent ERAD pathway 34/3662 81/15509 0.00018867 0.00112657 0.000677498 HSPA5/HERPUD1/SEL1L/DERL2/BAG6/PSMC6/USP14/SGTA/CCDC47/UBE4A/MAN1A1/TRIM25/FBXO44/ECPAS/DERL1/FAM8A1/RNF121/ERLIN2/DNAJB12/CLGN/TMUB1/VCP/CALR/YOD1/SVIP/UBE2J1/RNF5/BAG6/TRIM13/BAG6/BAG6/BAG6/BAG6/FBXO17 34
GO:0030901 midbrain development 34/3662 81/15509 0.00018867 0.00112657 0.000677498 HSPA5/FGFR2/RHOA/SIRT2/NDST1/CDC42/ACTB/KDM2B/SFRP1/DKK1/WNT3/WNT5A/HES1/GNB4/ATP5PB/PADI2/SYNGR3/YWHAH/FGF2/CSNK1D/SYPL2/CALM2/GLUD1/NR4A2/CALM3/SHH/NDRG2/CNP/CXCR2/MBP/NDUFS3/WNT3/WNT3/LRP6 34
GO:0106056 regulation of calcineurin-mediated signaling 22/3662 45/15509 0.000189474 0.00113028 0.000679729 PTBP1/IGF1/ATP2B4/ERBB3/GSK3B/NFAT5/PPP3CB/FHL2/DYRK2/SPPL3/CHP2/CIB1/MTOR/TNF/TNF/STIMATE/TNF/TNF/TNF/TNF/TNF/TNF 22
GO:0043242 negative regulation of protein-containing complex disassembly 33/3662 78/15509 0.000195012 0.00116108 0.000698255 SCIN/CLEC16A/PHF23/NAV3/SPTB/ADD2/ADD1/TPX2/MTPN/CAPZA1/APC/RDX/GSN/PLEKHH2/SCAF4/DMTN/SPTBN4/SPTA1/SPTBN2/TMEM39A/FLII/CIB1/SPTAN1/IQANK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TWF2 33
GO:1902117 positive regulation of organelle assembly 33/3662 78/15509 0.000195012 0.00116108 0.000698255 IFT88/RHOA/SPAG5/GSK3B/SH3GLB1/KCTD17/IL5/SNX4/SDC1/ELAPOR1/CNOT1/BECN1/LCP1/NUMA1/BBS4/MSN/ARHGAP35/CSF2/ATMIN/PDCD6IP/CEP135/MAPK15/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PIP4K2B/SEPTIN9 33
GO:0009110 vitamin biosynthetic process 15/3662 26/15509 0.000195972 0.00116456 0.000700344 SNAI2/PNPO/CYP27B1/IFNG/UBIAD1/CYP3A4/GFI1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:0010893 positive regulation of steroid biosynthetic process 15/3662 26/15509 0.000195972 0.00116456 0.000700344 IFNG/IL1A/NR1D1/PRKAA1/IGF1R/BMP6/WNT4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:0010958 regulation of amino acid import across plasma membrane 13/3662 21/15509 0.000199499 0.00117837 0.000708649 ARG1/PER2/ARL6IP5/ITGB1/SLC43A2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 13
GO:0051984 positive regulation of chromosome segregation 13/3662 21/15509 0.000199499 0.00117837 0.000708649 SIRT2/BIRC5/CDC6/SMC4/KAT2B/BECN1/CCNB1/CDCA8/NUMA1/NCAPG2/KAT5/AURKB/RCC2 13
GO:1903789 regulation of amino acid transmembrane transport 13/3662 21/15509 0.000199499 0.00117837 0.000708649 ARG1/PER2/ARL6IP5/ITGB1/SLC43A2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 13
GO:0007080 mitotic metaphase plate congression 23/3662 48/15509 0.000199627 0.00117837 0.000708649 NDC80/PIBF1/SEH1L/CHMP5/ZW10/BIRC5/NUDC/CHMP4B/RAB11A/KAT2B/BECN1/CHMP1A/CCNB1/PSRC1/CDCA8/CENPE/KIF2C/CENPC/BOD1/KAT5/CHMP6/AURKB/KIFC1 23
GO:0032689 negative regulation of interferon-gamma production 23/3662 48/15509 0.000199627 0.00117837 0.000708649 FOXP3/LILRB1/GATA3/C1QBP/INHBA/RARA/IL10/TLR4/CD96/NOD2/LGALS9/DDIT3/LILRB4/HMGB1/PDCD1LG2/CR1/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 23
GO:0033173 calcineurin-NFAT signaling cascade 23/3662 48/15509 0.000199627 0.00117837 0.000708649 PTBP1/IGF1/ATP2B4/ERBB3/GSK3B/NFATC2/NFAT5/PPP3CB/FHL2/DYRK2/SPPL3/CHP2/CIB1/MTOR/TNF/TNF/STIMATE/TNF/TNF/TNF/TNF/TNF/TNF 23
GO:0035307 positive regulation of protein dephosphorylation 23/3662 48/15509 0.000199627 0.00117837 0.000708649 PTBP1/PTPRC/PPP1R15A/HSP90AB1/PPP1R16B/TGFB1/CD33/PPP2R5D/PDGFRB/PTPA/PIN1/CALM2/GNA12/SPPL3/PPP1R15B/CALM3/PRKCD/NSMF/ANKLE2/MAGI2/PPIA/MTOR/PTPRC 23
GO:0032092 positive regulation of protein binding 32/3662 75/15509 0.00020084 0.00118328 0.000711602 HFE/HIPK2/ADD2/GSK3B/ADD1/FKBP1A/HSP90AB1/ABL1/MMP9/CSF3/PPP2CA/NPHP3/WNT5A/LRP1/USP9X/BMP2/PIN1/APOE/MEN1/DERL1/APP/TCF7L2/SPPL3/EPB41/SPTA1/TERT/CDK5/NMD3/BDNF/ANXA2/PRKN/B2M 32
GO:2001057 reactive nitrogen species metabolic process 32/3662 75/15509 0.00020084 0.00118328 0.000711602 CPS1/ATP2B4/ARG2/HSP90AB1/CYB5R3/ACP5/IFNG/MTARC2/PKD2/CLU/PTK2B/IL1B/ASS1/CD36/IL10/TLR4/CYP1B1/DDAH1/NOS3/CX3CR1/NQO1/TRPV1/CD47/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HBB 32
GO:0098813 nuclear chromosome segregation 91/3662 275/15509 0.00020165 0.00118692 0.000713794 CDC27/BAZ1B/CENPQ/ARID1B/MSH4/SIRT2/CDC42/SMC1A/ACTB/MLH1/SPAG5/NDC80/PIBF1/ATRX/SEH1L/CHMP5/ZW10/ANAPC5/BIRC5/NUDC/KIF4A/CDC6/BAG6/BCL7C/SMARCB1/CCNB1IP1/CHMP4B/RAB11A/CCNE1/SMC3/SMARCD2/BCL7A/FBXO5/MACROH2A1/SMC4/KAT2B/TTL/CDC20/NSL1/ARID1A/SLF2/TEX14/NAA50/PDS5A/CENPK/BECN1/MAU2/CHMP1A/TOP2A/CCNB1/PSRC1/CDCA8/APC/NUMA1/NUSAP1/KIF23/KNL1/ACTR2/CENPE/RB1/KIF2C/CENPC/BOD1/NCAPG2/SPC25/SMARCA5/EME1/GEM/BRD7/BUB1/CENPX/KAT5/ZWILCH/CCNE2/RMI2/CHMP6/RMI1/AURKB/RCC2/MAPK15/KMT5A/ARID2/BAG6/SYCE1L/BAG6/BAG6/BAG6/BAG6/KIFC1/SMARCB1/SPICE1 91
GO:0060348 bone development 74/3662 215/15509 0.000202821 0.00119268 0.000717258 HOXA11/PAFAH1B1/TYROBP/MBTPS2/LTF/IGF1/FGFR2/RHOA/FGFR3/ATP6AP1/TULP3/PTPRC/ZMPSTE24/GLG1/PLS3/ACP5/XYLT1/LILRB1/SFRP4/ENG/MAP2K6/NSD2/ZBTB16/SH2B3/MAPK14/PEX7/SMAD5/LEPR/P3H1/RUNX2/BMP2/SBDS/KDR/LRRC17/RARA/NOTCH2/ADAMTS7/TFAP2A/COL2A1/DYM/MEIS1/PDGFC/SERPINH1/GJA1/BMP6/MMP14/KIT/SLC38A10/SKI/STC1/ZNF385A/TGFBR2/SLC9B2/PITX2/RANBP3L/RPL13/RARG/LEP/FAM20C/PTPN11/ANXA2/RFLNB/NOTUM/COL27A1/SRC/COL13A1/TGM2/GH1/PTPRC/LOC102724560/LILRB1/LILRB1/LILRB1/LILRB1 74
GO:0009750 response to fructose 10/3662 14/15509 0.000204429 0.00119872 0.000720891 XBP1/KHK/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 10
GO:0031622 positive regulation of fever generation 10/3662 14/15509 0.000204429 0.00119872 0.000720891 IL1B/TNFRSF11A/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 10
GO:1905331 negative regulation of morphogenesis of an epithelium 10/3662 14/15509 0.000204429 0.00119872 0.000720891 BMP7/WNT5A/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 10
GO:0055065 metal ion homeostasis 146/3662 476/15509 0.000204815 0.00119985 0.00072157 HFE/LTF/SLC11A1/BAK1/CASR/HEXB/HERPUD1/CYBA/KCNQ1/KCNH2/ATP2B4/AP3D1/HYAL2/ATP6AP1/PRKACA/PICALM/SLC46A1/PTPRC/FTL/BAX/FKBP1A/P2RX7/SLC7A8/SLC22A17/ABL1/KCTD17/CD40/NUBP1/SLC39A14/HAMP/TFR2/ZNHIT1/CXCL12/CDH23/CCDC47/HPX/CALCA/SLC11A2/CYP27B1/VDR/IFNG/RHAG/PDE4D/WNT5A/ATP6V1A/IL1A/SLC30A3/EPAS1/FASLG/FBXL5/PKD2/CNNM1/PTK2B/TRIM24/KCNJ2/TMTC4/SLC25A23/CCR7/TRPV5/KDR/TNNI3/APOE/NDFIP1/C19orf12/IMMT/AP3B1/NT5E/ISCU/EDNRB/IREB2/ATP6V1G1/CCL21/FGF2/TMBIM6/SMAD4/SOD1/APP/SYPL2/TMCO1/CALM2/CORIN/ANK2/KLHL3/SLC12A9/SLC25A37/LCN2/GSTO1/ITPR1/BMP6/SLC24A2/STEAP2/ALAS2/STC1/CALM3/CCR5/CYB561A3/SELENON/SCNN1D/SLC30A7/DISC1/ATP1A1/MELTF/GPER1/FXN/TRPV6/EPB42/STIM1/FTH1/LETM1/PRKCE/CCL11/CCL19/ATP2A2/DDIT3/GRIN1/CD19/KCNJ10/GRINA/ERFE/CALR/F2/F2R/SLC8A1/SMDT1/BTBD9/PRKN/TMPRSS6/TMEM203/CLN3/FZD9/TRPV1/ELANE/TGM2/FIS1/KCTD7/TMEM199/ITGB3/PTPRC/CCL5/B2M/CCL5/TRPV5/TRPV6/ELANE/RASA3/PRKACA 146
GO:0002200 somatic diversification of immune receptors 31/3662 72/15509 0.000206004 0.00120568 0.000725074 PARP3/FOXP3/TCF3/TBX21/MLH1/PTPRC/MSH2/CD40/CD40LG/NBN/IL27RA/TGFB1/EXOSC3/NSD2/AICDA/IL4/BCL6/SHLD2/BCL11B/NDFIP1/IL10/SLC15A4/DCAF1/TNFSF13/RAG1/LIG4/RAG2/CD28/HMGB1/PRKDC/PTPRC 31
GO:1905952 regulation of lipid localization 58/3662 160/15509 0.000207134 0.0012103 0.000727855 PON1/CRY1/APOB/P2RX7/NFKBIA/MAP2K6/PPARD/TMEM30A/IL1A/KDM5B/FASLG/SPP1/CRHR1/CRY2/LRP1/IL1B/C3/APOE/CD36/IL6/THBS1/CYP19A1/ITGAV/EGF/FURIN/TNFRSF11A/REN/OSBPL11/BMP6/LDLRAP1/PRKCD/GDF9/SHH/SYK/ABCA3/PRELID1/TRIAP1/ARV1/LEP/PTPN2/LPL/ERFE/PTPN11/ADIPOQ/ANXA2/PRKN/TNF/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/YJEFN3/ITGB3/MIF 58
GO:0006611 protein export from nucleus 24/3662 51/15509 0.000207185 0.0012103 0.000727855 RANBP3/SP100/PRKACA/SIRT6/GSK3B/XPO1/RANGAP1/TGFB1/HSPA9/PARK7/EGR2/CSE1L/IL1B/NXT1/XPO4/ANP32B/TCF7L2/BAG3/RANBP3L/CDK5/AHCYL1/CALR/PTPN11/PRKACA 24
GO:0060840 artery development 38/3662 94/15509 0.000208784 0.00121849 0.000732781 PRDM1/NGFR/MYLK/NDST1/NOTCH3/LRP2/APOB/HECTD1/SMAD7/NPRL3/EYA1/TGFBR1/ENG/BMPR1A/ZMIZ1/FOLR1/MDK/PDGFRB/HES1/SNX17/PRRX1/PKD2/EGR2/LRP1/SOX4/APOE/SMAD6/FKBP10/NOTCH1/SHH/DCTN5/RBPJ/LEP/DDIT3/NOG/ARID2/SLC2A10/AKT3 38
GO:0043388 positive regulation of DNA binding 25/3662 54/15509 0.000212341 0.00123809 0.000744565 IGF1/HIPK2/SIRT2/MMP9/ERCC2/TGFB1/EDF1/GATA3/IFNG/HES1/PARK7/NGF/IRF4/EGF/RB1/PARP1/CALM2/POU4F2/POU4F1/SKI/CALM3/PRKN/H1-0/HMGB1/NME1 25
GO:0043627 response to estrogen 29/3662 66/15509 0.000213648 0.00124454 0.000748446 HOXA11/F7/IL4R/OPRK1/MMP2/ESR1/SFRP1/GATA3/CCND1/CYP27B1/PDGFRB/IGFBP2/TRIM25/TRIM24/ASH2L/EPO/ARPC1B/RARA/WBP2/SMAD6/HAPLN3/PELP1/MMP14/TGFBR2/TNFRSF11B/SERPINB9/MME/HOXA10/CD24 29
GO:0016447 somatic recombination of immunoglobulin gene segments 26/3662 57/15509 0.000215322 0.00125311 0.000753601 PARP3/FOXP3/TCF3/TBX21/MLH1/PTPRC/MSH2/CD40/CD40LG/NBN/IL27RA/TGFB1/EXOSC3/NSD2/AICDA/IL4/BCL6/SHLD2/NDFIP1/IL10/SLC15A4/TNFSF13/LIG4/CD28/PRKDC/PTPRC 26
GO:0019731 antibacterial humoral response 28/3662 63/15509 0.000215735 0.00125434 0.000754337 LTF/CTSG/SEMG1/H2BC11/SFTPD/NOD2/FGA/H2BC21/ELANE/RPL39/HLA-E/HLA-E/HLA-A/HLA-A/HLA-A/HLA-A/HLA-E/HLA-A/HLA-A/HLA-E/HLA-E/HLA-A/HLA-E/HLA-A/HLA-E/H2BC6/H2BC7/ELANE 28
GO:0035196 miRNA processing 27/3662 60/15509 0.000216372 0.00125487 0.000754658 PUM2/TUT7/ZMPSTE24/ESR1/AGO1/ZC3H7B/TGFB1/DDX5/ZC3H7A/MYCN/IL6/NCBP1/TARBP2/EGFR/PUS10/TERT/TRUB1/SMAD2/SPOUT1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 27
GO:0048565 digestive tract development 49/3662 130/15509 0.000216431 0.00125487 0.000754658 CPS1/ALX4/KCNQ1/PRDM1/FGFR2/TP63/GLI2/CHD8/SFRP1/HOXA5/CCKBR/NPHP3/WNT5A/HES1/ID2/SFRP5/NKX2-2/ALDH1A2/ASS1/PDGFRA/AHI1/EDNRB/HLX/RB1/CYP1A1/PDGFC/EGFR/NOTCH1/NODAL/KIT/TGFBR2/SHH/SLC4A2/CXCL8/SMAD2/FOXL1/TYMS/OXTR/YIPF6/EPHB3/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 49
GO:0016331 morphogenesis of embryonic epithelium 52/3662 140/15509 0.000216434 0.00125487 0.000754658 WNT16/FGFR2/PRKACA/TP63/TULP3/LRP2/TMED2/KDM2B/HECTD1/ABL1/CECR2/MTHFD1/BMP7/TSC2/SFRP1/TGFB1/DVL1/GATA3/FOLR1/NPHP3/WNT5A/MTHFD1L/SOX4/ALDH1A2/LAMA5/RARA/GRSF1/TFAP2A/BBS4/VEGFC/NODAL/SKI/ARHGAP35/DVL3/WNT4/VANGL2/CASP3/SHH/SEMA4C/RARG/GLMN/SETD2/RGMA/NOG/WNT7B/BRD2/TCTN1/BRD2/BRD2/BRD2/BRD2/PRKACA 52
GO:0006006 glucose metabolic process 62/3662 174/15509 0.000221611 0.00128369 0.000771987 BAD/CRY1/IGF1/H6PD/KCNQ1/PKM/PDK3/SIRT6/DUSP12/ZMPSTE24/SLC25A1/PCK2/SLC39A14/GPI/GSK3A/BRAT1/ENO3/ALDOC/PPARD/MAPK14/KAT2B/LEPR/SERP1/DYRK2/SESN2/G6PC1/PER2/PRKAA1/PMAIP1/GALM/IGFBP3/OGT/SOGA1/DLAT/FOXO1/RANBP2/ADIPOR1/OMA1/ATF3/NNMT/GPD1/MST1/LEP/PTPN2/ERFE/ADIPOQ/SLC25A10/GDPGP1/PRKN/KCNJ11/USP7/WDR5/SRC/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/GPI 62
GO:0010923 negative regulation of phosphatase activity 19/3662 37/15509 0.000228723 0.00132118 0.000794535 ROCK1/GSK3B/PPP1R15A/FKBP1A/URI1/PTPA/MASTL/CRY2/STYXL1/BOD1/TNF/PPP1R11/TNF/TNF/TNF/TNF/TNF/TNF/TNF 19
GO:0021762 substantia nigra development 19/3662 37/15509 0.000228723 0.00132118 0.000794535 HSPA5/RHOA/SIRT2/CDC42/ACTB/GNB4/ATP5PB/PADI2/SYNGR3/YWHAH/FGF2/SYPL2/CALM2/GLUD1/CALM3/NDRG2/CNP/MBP/NDUFS3 19
GO:0140467 integrated stress response signaling 19/3662 37/15509 0.000228723 0.00132118 0.000794535 HSPA5/TMED2/PPP1R15A/CEBPE/CREB3/TMEM33/PPP1R15B/OMA1/FOS/EIF2AK3/CEBPB/DDIT3/PTPN2/FOSL1/JUN/MAF/MAFB/CEBPD/CEBPA 19
GO:1901654 response to ketone 66/3662 188/15509 0.000231287 0.00133475 0.000802694 BAD/CD38/HOXA11/CPS1/FOXP3/CYBA/F7/GNB1/HOXA9/PCK2/SFRP1/PLAT/GPI/TGFB1/AHR/RPS6KB1/RECQL5/CCND1/XRN1/PARK7/ARG1/FOXO3/SPP1/KLF9/FOSB/NKX2-2/CCR7/ELK1/EPO/ASS1/PRKAA1/WBP2/CCL21/FDX1/THBS1/CYP1B1/IGF1R/PARP1/SLIT2/MSN/CALM3/SCNN1D/ADCY1/CYBB/DDIT4/PTAFR/FOS/PRKCE/BCL2L1/CCL19/FOSL1/A2M/TYMS/CALR/OXTR/NQO1/PAPPA/SLIT3/AKR1C3/SRC/MBP/F5/HOXA10/TXNIP/NEFL/GPI 66
GO:0040029 epigenetic regulation of gene expression 51/3662 137/15509 0.000232366 0.00133972 0.000805686 KDM1A/ARID1B/KCNQ1/ARID4B/SPI1/SIRT2/MBD3/SIRT6/AXIN1/DOT1L/GSK3A/EZH2/EZH1/AICDA/FAM172A/MACROH2A1/KAT2B/HDAC1/PADI2/ARID1A/DNMT3A/HELLS/DNMT1/WBP2/PRMT7/PPHLN1/TET1/TDG/RB1/OGT/HMGA2/SMARCA5/CTBP1/LMNA/RBM15/H3-3A/PPM1D/EXOSC10/MSL2/GLMN/SUZ12/PCGF5/H1-0/HMGB1/WDR5/PHF2/L3MBTL3/RBM15B/H3C6/H3C10/H3C2 51
GO:0001841 neural tube formation 40/3662 101/15509 0.000241771 0.00139136 0.000836741 PRKACA/TULP3/LRP2/TMED2/KDM2B/HECTD1/ABL1/CECR2/MTHFD1/BMP7/TSC2/SFRP1/TGFB1/DVL1/FOLR1/NPHP3/WNT5A/MTHFD1L/SOX4/RARA/BBS4/NODAL/SKI/ARHGAP35/DVL3/VANGL2/CASP3/SEMA4C/RARG/GLMN/SETD2/RGMA/NOG/BRD2/TCTN1/BRD2/BRD2/BRD2/BRD2/PRKACA 40
GO:1901989 positive regulation of cell cycle phase transition 40/3662 101/15509 0.000241771 0.00139136 0.000836741 CDC27/KMT2E/PAF1/ANAPC5/CDC6/CDC7/APEX1/CDC25B/RAB11A/EZH2/CCND1/FBXO5/CCND3/HSPA2/CCNB1/RDX/RB1/CUL4A/CYP1A1/APP/DTL/DYRK3/EGFR/ADAMTS1/LSM11/CUL4B/DBF4B/TERT/RRM1/CDK1/RRM2/RCC2/MAPK15/NPM1/PLCB1/CHEK2/CDK10/PBX1/TFDP1/PAGR1 40
GO:0035066 positive regulation of histone acetylation 16/3662 29/15509 0.000243972 0.00139487 0.000838851 BAZ1B/SNAI2/FOXP3/SMARCB1/GATA3/SF3B1/DEK/LIF/MYBBP1A/WBP2/SMAD4/SMARCA5/BRD7/MUC1/SMARCB1/TADA2A 16
GO:0061437 renal system vasculature development 16/3662 29/15509 0.000243972 0.00139487 0.000838851 NOTCH3/ANGPT2/PDGFB/BMP7/ACTA2/PDGFRB/HES1/PKD2/TEK/EGR1/NOTCH2/PDGFRA/NOTCH1/IL6R/ITGB3/PECAM1 16
GO:0061440 kidney vasculature development 16/3662 29/15509 0.000243972 0.00139487 0.000838851 NOTCH3/ANGPT2/PDGFB/BMP7/ACTA2/PDGFRB/HES1/PKD2/TEK/EGR1/NOTCH2/PDGFRA/NOTCH1/IL6R/ITGB3/PECAM1 16
GO:1902751 positive regulation of cell cycle G2/M phase transition 16/3662 29/15509 0.000243972 0.00139487 0.000838851 CDC7/CDC25B/RAB11A/CCND1/FBXO5/HSPA2/CCNB1/APP/DTL/DYRK3/DBF4B/RRM1/CDK1/RCC2/NPM1/PBX1 16
GO:0002774 Fc receptor mediated inhibitory signaling pathway 9/3662 12/15509 0.000244181 0.00139487 0.000838851 LILRB1/LILRB4/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 9
GO:0035509 negative regulation of myosin-light-chain-phosphatase activity 9/3662 12/15509 0.000244181 0.00139487 0.000838851 ROCK1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 9
GO:0071872 cellular response to epinephrine stimulus 9/3662 12/15509 0.000244181 0.00139487 0.000838851 KCNQ1/ATP2B4/SIRT2/PRKACA/PKLR/ADIPOQ/PDE4B/PKLR/PRKACA 9
GO:0120188 regulation of bile acid secretion 9/3662 12/15509 0.000244181 0.00139487 0.000838851 PRKAA1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 9
GO:0030832 regulation of actin filament length 53/3662 144/15509 0.000246626 0.00140754 0.000846469 SCIN/CYFIP2/RHOA/SPTB/WDR1/ADD2/ACTN2/ADD1/HCK/COTL1/PYCARD/MTPN/CXCL12/CSF3/ARPC3/DBN1/CAPZA1/PTK2B/DSTN/CCR7/CDC42EP1/ARPC1B/DBNL/CCL21/RDX/BBS4/SLIT2/ARHGAP18/GSN/CDC42EP2/PLEKHH2/DMTN/ARHGAP35/SPTBN4/ALOX15/ARPC5/CDC42EP3/SPTA1/PRKCD/RICTOR/PRKCE/CCL11/SPTBN2/FLII/GRB2/SPTAN1/MTOR/IQANK1/TMSB4X/PDXP/ARPC1A/TWF2/BRK1 53
GO:0014074 response to purine-containing compound 50/3662 134/15509 0.000249376 0.00142193 0.000855122 KDM1A/CPS1/HSPA5/KCNQ1/P2RX5/P2RX7/APEX1/GATA1/PLAT/PIK3CG/AHR/RAPGEF1/AREG/XRN1/STAT1/SDC1/PKD2/PTK2B/IL1B/FOSB/CDO1/ASS1/PRKAA1/NT5E/FDX1/CYP1B1/SOD1/APP/CARM1/PKLR/REN/DMTN/STC1/SELENON/INHBB/GPD1/PTAFR/FOS/BSG/PDE3A/FOSL1/ADIPOQ/SLC8A1/ZFP36L1/KCNJ11/P2RX2/TRPV1/PDXP/P2RY11/PKLR 50
GO:0060412 ventricular septum morphogenesis 20/3662 40/15509 0.00025089 0.00142925 0.000859523 FGFR2/SMAD7/TGFBR1/BMPR1A/NSD2/WNT5A/HES1/SOX4/SMAD4/SLIT2/NOTCH1/RBM15/TGFBR2/HEYL/NOS3/RBPJ/ZFPM2/NKX2-5/NOG/SLIT3 20
GO:0032259 methylation 108/3662 338/15509 0.000253834 0.00144469 0.000868809 NFYA/KDM1A/KMT2E/PAF1/AASS/ARID4B/PRDM1/KDM4A/NFYC/SPI1/BUD23/MBD3/ZMPSTE24/ATRX/MECOM/DNMT3B/COMT/SMARCB1/SNRPD3/PCIF1/SETD6/DOT1L/FBL/GSK3A/EZH2/GATA3/TRDMT1/EZH1/NSD2/NOP2/HCFC2/MACROH2A1/KDM3A/ASH1L/MTR/NSUN4/DPH5/MYB/PHF19/DNMT3A/HELLS/EEF1AKMT3/H1-3/PRMT1/ASH2L/PRDM12/DNMT1/PRMT7/MEN1/CMTR1/TPMT/ALKBH8/THUMPD2/TET1/SNRPF/SKIC8/CYP1A1/CYP1A2/SMAD4/CARM1/METTL25B/PARP1/SNRPG/BOD1/WTAP/OGT/NSD3/SMARCA5/RNF20/BTG2/PRMT2/LMNA/GFI1/RBM15/PYGO2/NSD1/NNMT/SNRPD1/GATAD2A/SETD5/H1-4/FOS/MGMT/PPM1D/COPRS/HCFC1/TRMT112/TDRD12/LARP7/TYMS/WDR6/SUZ12/SETD2/SETD3/KMT5A/TET3/H1-2/TRMT2B/PAX5/WDR5/WDR5B/NCOA6/SPOUT1/PCMTD2/RBM15B/SMARCB1/PAGR1/EMG1 108
GO:0048738 cardiac muscle tissue development 71/3662 206/15509 0.000257612 0.00146484 0.000880931 IGF1/PKP2/ERBB3/MAP2K4/FGFR2/CDC42/SIRT6/ACTN2/TP73/LRP2/ZMPSTE24/NOX4/FKBP1A/DSP/ABL1/BMP7/SMAD7/NDRG4/NPRL3/TGFB1/HAMP/GSK3A/TGFBR1/ENG/BMPR1A/DKK1/MAPK14/BVES/SMAD5/PDGFRB/WNT5A/FHL2/ID2/TNNT2/OBSL1/BMP2/PRMT1/ALDH1A2/TNNI3/RARA/MYH11/NOTCH2/PDGFRA/FGF2/ARRB2/SMAD4/NOTCH1/ITGB1/POU4F1/GJA1/SKI/TNNI1/RUNX1/LMNA/MAML1/PDLIM5/TGFBR2/FRS2/RBPJ/ZFPM2/CDK1/S1PR1/PLEC/CALR/SLC8A1/NKX2-5/NOG/ARID2/MTOR/MYH11/PTEN 71
GO:0014002 astrocyte development 21/3662 43/15509 0.000268863 0.00152595 0.000917678 GRN/IFNG/LRP1/IL1B/NR1D1/KRAS/TSPAN2/IL6/TLR4/APP/LAMB2/POU3F2/ROR1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 21
GO:0014020 primary neural tube formation 38/3662 95/15509 0.000269659 0.00152595 0.000917678 PRKACA/TULP3/LRP2/TMED2/KDM2B/HECTD1/ABL1/CECR2/MTHFD1/BMP7/TSC2/SFRP1/TGFB1/DVL1/FOLR1/NPHP3/WNT5A/MTHFD1L/RARA/BBS4/NODAL/SKI/ARHGAP35/DVL3/VANGL2/CASP3/SEMA4C/RARG/GLMN/SETD2/RGMA/NOG/BRD2/BRD2/BRD2/BRD2/BRD2/PRKACA 38
GO:0001788 antibody-dependent cellular cytotoxicity 8/3662 10/15509 0.000270328 0.00152595 0.000917678 FCGR2B/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 8
GO:0010693 negative regulation of alkaline phosphatase activity 8/3662 10/15509 0.000270328 0.00152595 0.000917678 TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 8
GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation 8/3662 10/15509 0.000270328 0.00152595 0.000917678 RUNX3/CBFB/RUNX1/SOCS1/LILRB4/LILRB4/LILRB4/LILRB4 8
GO:0046968 peptide antigen transport 8/3662 10/15509 0.000270328 0.00152595 0.000917678 TAP2/TAP2/TAP2/TAP2/TAP2/TAP2/TAP2/TAP2 8
GO:1905242 response to 3,3',5-triiodo-L-thyronine 8/3662 10/15509 0.000270328 0.00152595 0.000917678 TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 8
GO:2001272 positive regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 8/3662 10/15509 0.000270328 0.00152595 0.000917678 TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 8
GO:0032634 interleukin-5 production 12/3662 19/15509 0.000270999 0.00152696 0.000918285 FOXP3/IL5RA/GATA3/PDE4D/RARA/TNFRSF21/LILRB4/IL1RAP/CRLF2/LILRB4/LILRB4/LILRB4 12
GO:0032674 regulation of interleukin-5 production 12/3662 19/15509 0.000270999 0.00152696 0.000918285 FOXP3/IL5RA/GATA3/PDE4D/RARA/TNFRSF21/LILRB4/IL1RAP/CRLF2/LILRB4/LILRB4/LILRB4 12
GO:0071375 cellular response to peptide hormone stimulus 89/3662 270/15509 0.000272701 0.00153515 0.000923213 CPS1/CYBA/PKM/ROCK1/ACTN2/GSK3B/RAB10/PXN/CDC6/XBP1/RANGAP1/APEX1/PCK2/TSC2/CSK/PLAT/SLC39A14/JAK3/GSK3A/RPS6KB1/CCND3/KAT2B/NCL/STAT1/ARG1/NR4A3/CRHR1/INHBA/NR4A1/NCOA5/IL1B/MAX/STAT5A/GDF15/ASS1/PRKAA1/LPIN3/MEN1/APC/SORL1/CYP1B1/RB1/IGF1R/RAB13/PKLR/PARP1/CCNA2/PIK3R1/OGT/EIF4EBP2/SESN3/SOGA1/FOXO1/POU4F2/NR4A2/APPL1/ADIPOR1/SHC1/JAK1/SCNN1D/INHBB/PRKCD/GPER1/ZNF592/SLC27A4/AHCYL1/PTK2/FOS/SLC25A33/RELA/ESRRA/STAT5B/LEP/PTPN2/LPL/GRB2/ERFE/PTPN11/ADIPOQ/PLCB1/FOXO4/SOCS1/ZFP36L1/SRC/PRKDC/ITGB3/GH1/PKLR/PIP4K2B 89
GO:0032469 endoplasmic reticulum calcium ion homeostasis 14/3662 24/15509 0.000274009 0.00154112 0.0009268 BAK1/HERPUD1/BAX/KCTD17/CCDC47/TMTC4/TMBIM6/APP/TMCO1/ITPR1/ATP2A2/GRINA/TGM2/FIS1 14
GO:0048332 mesoderm morphogenesis 31/3662 73/15509 0.000277894 0.00156155 0.000939087 HOXA11/ITGA3/FGFR2/PRKACA/ITGA8/BMP7/AXIN1/EYA1/GPI/BMPR1A/DKK1/WNT3/WNT5A/INHBA/TWSG1/ARMC5/EPHA2/HMGA2/ITGB1/GJA1/NODAL/SMAD2/SETD2/NOG/NF2/TXNRD1/ITGB3/WNT3/WNT3/GPI/PRKACA 31
GO:0044000 movement in host 59/3662 165/15509 0.00027914 0.00156713 0.000942444 CD4/CD74/HYAL2/MID2/CHMP5/ICAM1/CHMP4B/VAPA/KPNA3/SLC1A5/TRIM14/EFNB3/CD81/CD86/VAMP8/TRIM25/CD80/CXCR4/NUP153/NECTIN2/CHMP1A/TRIM5/TRIM22/ARL8B/ITGAV/SLC7A1/FURIN/EPHA2/EGFR/GSN/NCAM1/ITGB1/CCR5/ANPEP/TRIM68/SLC3A2/LGALS9/CXCL8/GYPA/CDK1/TRIM8/BSG/DAG1/CHMP6/CIITA/EXOC7/SLC52A2/IFITM1/PLSCR1/HMGB1/PPIA/CD55/SRC/DPP4/WWP2/CR1/TRIM26/ITGB3/ITCH 59
GO:0060147 regulation of post-transcriptional gene silencing 23/3662 49/15509 0.000292788 0.00164226 0.000987626 PUM2/ELAVL1/ZMPSTE24/ESR1/TGFB1/DDX5/ZFP36/AJUBA/MYCN/IL6/EGFR/TERT/TRUB1/FOCAD/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 23
GO:1905330 regulation of morphogenesis of an epithelium 28/3662 64/15509 0.000297929 0.00166959 0.00100406 SNAI2/HGF/SIRT6/ESR1/ABL1/BMP7/SFRP1/GATA3/MDK/WNT5B/WNT5A/LIF/FGF2/EGF/ITGAX/GJA1/WNT4/SHH/NOG/FKBPL/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 28
GO:0001843 neural tube closure 36/3662 89/15509 0.000298782 0.00167135 0.00100512 PRKACA/TULP3/LRP2/TMED2/KDM2B/HECTD1/ABL1/CECR2/MTHFD1/TSC2/SFRP1/TGFB1/DVL1/FOLR1/NPHP3/WNT5A/MTHFD1L/RARA/BBS4/SKI/ARHGAP35/DVL3/VANGL2/CASP3/SEMA4C/RARG/GLMN/SETD2/RGMA/NOG/BRD2/BRD2/BRD2/BRD2/BRD2/PRKACA 36
GO:0032091 negative regulation of protein binding 36/3662 89/15509 0.000298782 0.00167135 0.00100512 KDM1A/HFE/ROCK1/ACTB/GSK3B/BAX/TFIP11/PDGFB/ADNP/TLE5/DVL1/MAPK8/DKK1/ITGA4/PARK7/IFIT2/TEX14/CDKN1A/ID1/PIN1/IL10/SORL1/TDG/TMBIM6/ARRB2/DISC1/PRKCD/GOLGA2/ADRB2/ATP2A2/CTNNBIP1/AURKB/ADIPOQ/RGMA/NOG/B2M 36
GO:0045599 negative regulation of fat cell differentiation 24/3662 52/15509 0.000299321 0.00167285 0.00100602 SIRT2/RUNX1T1/MMP11/AXIN1/TGFB1/GATA3/WNT5A/BMP2/IL6/FOXO1/ZFP36L2/GPER1/ZFPM2/DDIT3/ADIPOQ/C1QL4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 24
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 27/3662 61/15509 0.000301654 0.00168319 0.00101224 HFE/BMP7/SMAD7/TGFB1/TGFBR1/ENG/BMPR1A/DKK1/INHBA/LRP1/BMP2/PIN1/TWSG1/GDF15/SMAD6/SMAD4/BMP6/NODAL/INHBB/TGFBR2/GDF9/NOG/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CSNK2B 27
GO:0052548 regulation of endopeptidase activity 112/3662 354/15509 0.000301715 0.00168319 0.00101224 BAD/CASP10/LTF/HGF/BIRC3/FAS/CD44/BAK1/CYFIP2/NGFR/RHOA/ROCK1/TP63/PICALM/BAX/PEBP1/BIRC5/PSME1/PSMA3/MMP9/BIRC7/USP14/MEFV/PYCARD/PDCD5/GPI/TFPI2/DNAJB6/NOD1/CASP2/SERPINE1/AMBP/CRYAB/PERP/HSPE1/PARK7/HDAC1/FASLG/SERPINC1/TNFSF10/RECK/NR4A1/SEMG1/C3/SPINK2/ADRM1/PSME3/NGF/AKIRIN2/MICAL1/SERPINE2/ANP32B/MTCH1/SORL1/THBS1/BCL2L10/FURIN/ARRB2/PMAIP1/APP/CCN1/ARL6IP5/GSN/SERPINH1/CRIM1/BCL2L11/CAST/NODAL/FABP1/GPER1/INTS1/SYK/VCP/RAG1/FADD/LGALS9/PRELID1/EFNA1/MGMT/SERPINB9/TRIAP1/EIF2AK3/A2M/GRIN1/PAK2/F2R/ANXA2/CARD9/HMGB1/SPOCK3/DAPK1/SRC/MAP3K5/MBP/CR1/TNF/PSENEN/TNF/FIS1/MAGEA3/TNF/TNF/TNF/TNF/TNF/TNF/NAIP/PDCD6/NAIP/CRIM1/NAIP/GPI 112
GO:0060135 maternal process involved in female pregnancy 25/3662 55/15509 0.00030272 0.00168728 0.0010147 ITGA3/PRDM1/DAZAP1/PGR/TMED2/ESR1/ANGPT2/KLF1/PTN/CYP27B1/VDR/PPARD/ASH1L/ARG1/SPP1/LIF/MEN1/PARP1/NODAL/STC1/WNT4/LGALS9/BSG/EPOR/LOC102724560 25
GO:2000036 regulation of stem cell population maintenance 26/3662 58/15509 0.000303371 0.00168939 0.00101597 ARID4B/BICRA/ELAVL1/TP63/ACTB/KDM2B/BCL7C/SMARCB1/BMP7/RBBP7/PTN/BCL7A/KDM3A/HDAC1/ARID1A/CNOT1/LOXL2/TAF5L/TET1/OGT/HMGA2/NODAL/TAF6L/RBBP4/SAP30/SMARCB1 26
GO:2000758 positive regulation of peptidyl-lysine acetylation 18/3662 35/15509 0.000325329 0.00180889 0.00108783 BAZ1B/SNAI2/FOXP3/SMARCB1/GATA3/SF3B1/SOX4/DEK/LIF/PRKAA1/MYBBP1A/WBP2/SMAD4/SMARCA5/BRD7/MUC1/SMARCB1/TADA2A 18
GO:2000058 regulation of ubiquitin-dependent protein catabolic process 57/3662 159/15509 0.000325413 0.00180889 0.00108783 HFE/RNF14/UFL1/HERPUD1/HIPK2/SIRT2/CSNK2A2/MKRN2/SIRT6/UBE2K/GSK3B/XPO1/HECTD1/BAG6/HSP90AB1/USP14/SMAD7/N4BP1/AXIN1/SGTA/GSK3A/DVL1/USP5/PDCL3/PARK7/CDC20/RAD23B/CLU/PTK2B/USP9X/CBFA2T3/HSPBP1/EGF/CSNK1D/GNA12/TLK2/OGT/EIF3H/RNF144A/DISC1/RYBP/RCHY1/SHH/VCP/PTK2/GLMN/MAGEF1/PRKN/USP7/SVIP/BAG6/BAG6/BAG6/BAG6/BAG6/CEBPA/PTEN 57
GO:0031647 regulation of protein stability 93/3662 286/15509 0.000341366 0.00189587 0.00114014 RPAP3/MYLIP/TYROBP/IGF1/GRN/USP28/PER3/CTSA/VPS35/SEL1L/FBXW11/SIRT6/NDC80/BAG6/HSP90AB1/SH3GLB1/POLR2E/RASSF2/SMAD7/UBL4A/PYCARD/URI1/BAG1/DVL1/CRYAB/HSPA8/CD81/PFDN1/PDCL3/PARK7/P3H1/CLU/TARDBP/TRIM24/PFDN5/USP9X/SOX4/BMP2/NR1D1/UXT/PIN1/FLOT2/KRAS/CCNH/CCT7/STXBP1/DERL1/SERF2/ANK2/PIK3R1/GSN/BAG3/GNAQ/B4GALT5/LMNA/DVL3/PEX19/RNF149/PRKCD/NAA15/CASP3/TERT/BTRC/CCT2/TRIM44/CDKN2AIP/TNIP2/EFNA1/AHSP/OTUD3/TADA3/HCFC1/CALR/NPM1/CHEK2/PRKN/NF2/USP7/SRC/DDI2/PARVA/GLMP/PFDN6/RNF5/BAG6/ZSWIM7/BAG6/BAG6/BAG6/BAG6/DDOST/PRKDC/PTEN 93
GO:0006898 receptor-mediated endocytosis 79/3662 236/15509 0.00034365 0.00190554 0.00114596 SELE/CD9/HFE/AP2S1/HMMR/FCGR2B/PICALM/LRP2/ACHE/MICALL1/LILRB1/TFR2/SERPINE1/AP1S1/SFRP4/DKK1/UNC119/FOLR1/CD81/IL4/ITGA4/SNX17/SDC1/CLU/CLTA/LRP1/C3/APOE/CAP1/SFTPD/CD36/AHI1/DBNL/RABEPK/CCL21/SORL1/ITGAV/EGF/ARRB2/VLDLR/ITGB1/BICD1/LDLRAP1/ARHGAP27/ITGB2/AP2M1/CXCR1/TGFBR2/SLC9B2/SYK/AMN/ADRB2/CXCL8/ITGAM/CD14/CCL19/GRB2/CXCR2/ADIPOQ/ANXA2/CNTN2/HGS/LILRB4/MAGI2/CLN3/BTBD8/IGF2R/DPP4/DNM3/ITGB3/B2M/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4/LRP6 79
GO:0002082 regulation of oxidative phosphorylation 15/3662 27/15509 0.000344953 0.00190554 0.00114596 RHOA/PPIF/SLC25A23/AK4/VCP/SLC25A33/PDE12/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:0072012 glomerulus vasculature development 15/3662 27/15509 0.000344953 0.00190554 0.00114596 NOTCH3/ANGPT2/PDGFB/BMP7/ACTA2/PDGFRB/HES1/TEK/EGR1/NOTCH2/PDGFRA/NOTCH1/IL6R/ITGB3/PECAM1 15
GO:0072574 hepatocyte proliferation 15/3662 27/15509 0.000344953 0.00190554 0.00114596 XBP1/PTN/MDK/TNFAIP3/NOTCH2/IL6/CEBPB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:0072575 epithelial cell proliferation involved in liver morphogenesis 15/3662 27/15509 0.000344953 0.00190554 0.00114596 XBP1/PTN/MDK/TNFAIP3/NOTCH2/IL6/CEBPB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:1902235 regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway 15/3662 27/15509 0.000344953 0.00190554 0.00114596 HERPUD1/XBP1/CREB3/PARK7/SERINC3/TMBIM6/PMAIP1/BCL2L11/BCL2L1/EIF2AK3/DDIT3/PTPN2/GRINA/PRKN/MAGEA3 15
GO:0061041 regulation of wound healing 48/3662 129/15509 0.000353576 0.00195144 0.00117356 CD9/F7/MYLK/APOH/XBP1/PDGFB/FERMT1/PLAT/SERPINE1/ACTA2/SH2B3/SMOC2/HBEGF/SERPINC1/TNFAIP3/CXCR4/APOE/EPHB2/PDGFRA/CD36/SERPINE2/THBS1/FGF2/ADAMTS18/ITGB1/DMTN/WNT4/PRKCD/NOS3/PRDX2/PTK2/PRKCE/FGG/FGA/HRAS/F2/F2R/ANXA2/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTEN 48
GO:0010762 regulation of fibroblast migration 19/3662 38/15509 0.000356791 0.00196219 0.00118003 HYAL2/TGFB1/HAS1/ACTA2/CORO1C/GNA13/AKAP12/THBS1/FGF2/GNA12/ITGB1/APPL1/DMTN/PTK2/PRKCE/RCC2/SLC8A1/CLN3/ITGB3 19
GO:0035136 forelimb morphogenesis 19/3662 38/15509 0.000356791 0.00196219 0.00118003 HOXA11/ALX4/TP63/HOXA9/ATRX/RPGRIP1L/WNT3/ZBTB16/RECK/RUNX2/HOXD9/ALDH1A2/TFAP2A/RNF165/CRABP2/SHH/ZNF358/WNT3/WNT3 19
GO:0098751 bone cell development 19/3662 38/15509 0.000356791 0.00196219 0.00118003 PAFAH1B1/TYROBP/LTF/ATP6AP1/LILRB1/SH2B3/NOTCH2/MEIS1/KIT/ZNF385A/SLC9B2/FAM20C/PTPN11/ANXA2/SRC/LILRB1/LILRB1/LILRB1/LILRB1 19
GO:1903573 negative regulation of response to endoplasmic reticulum stress 19/3662 38/15509 0.000356791 0.00196219 0.00118003 UFL1/HSPA5/HERPUD1/PPP1R15A/XBP1/USP14/BFAR/SGTA/CREB3/PARK7/CLU/TMBIM6/USP25/PPP1R15B/BCL2L1/GRINA/PRKN/SVIP/MAGEA3 19
GO:0010948 negative regulation of cell cycle process 89/3662 272/15509 0.000359503 0.00197536 0.00118794 CRY1/BAZ1B/FHL1/USP28/RAD51/NDC80/ATRX/ZW10/BIRC5/CDC6/MSH2/BMP7/RBBP8/NUBP1/NBN/DOT1L/CASP2/EZH2/CCL2/CCND1/FBXO5/MAPK14/CCNG1/RAD50/MACROH2A1/BCL6/KAT2B/CDC20/PKD2/TEX14/INHBA/CDKN1A/LIF/MEN1/CCNB1/CDCA8/APC/NABP2/BRCA2/RB1/CUL4A/DTL/INTS3/CTDSP1/PLK2/SPC25/ZFP36L2/SMARCA5/XPC/EME1/PRMT2/BRSK1/MRNIP/RPL26/GPER1/BRD7/WEE1/RFWD3/BUB1/AVEN/CDK1/TRIAP1/RHNO1/NABP1/ZWILCH/CTDSP2/AURKAIP1/AURKB/PTPN11/NPM1/CACNB4/CEP63/CHEK2/FOXO4/MUC1/ZFP36L1/H2AX/KANK2/GIGYF2/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/PRKDC/HLA-G/PTEN 89
GO:0031650 regulation of heat generation 11/3662 17/15509 0.000364467 0.00199909 0.00120222 IL1B/EDNRB/TNFRSF11A/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 11
GO:0045945 positive regulation of transcription by RNA polymerase III 11/3662 17/15509 0.000364467 0.00199909 0.00120222 BAZ1B/CHD8/ELL/SF3B1/INHBA/DEK/ICE2/MYBBP1A/SMARCA5/BRF1/MTOR 11
GO:0030307 positive regulation of cell growth 53/3662 146/15509 0.00036507 0.00200062 0.00120314 CD38/PAFAH1B1/IGF1/CYBA/NTN1/RHOA/CDC42/DERL2/SLC23A2/KDM2B/ADNP/SMAD7/SFRP1/DDX49/HAMP/MTPN/BRAT1/TGFBR1/CXCL12/WNT3/EIF4G2/HBEGF/DBN1/FN1/PTK2B/CXCR4/NGF/DBNL/NCBP1/CRABP2/SYT2/EGFR/POU4F2/MMP14/DISC1/H3-3A/RICTOR/FXN/CDKN2AIP/LPAR3/SLC25A33/BDNF/CDH4/F2/CIB1/PRKN/PRR5/TEAD1/MTOR/GDI1/TWF2/WNT3/WNT3 53
GO:0036503 ERAD pathway 41/3662 106/15509 0.000366744 0.00200802 0.00120759 HSPA5/HERPUD1/ATXN3/SEL1L/DERL2/BAG6/XBP1/PSMC6/USP14/UGGT2/SGTA/CCDC47/UBE4A/MAN1A1/TRIM25/FBXO44/ECPAS/DERL1/FAM8A1/RNF121/ERLIN2/DNAJB12/CLGN/USP25/TMUB1/VCP/UBXN6/BRSK2/CALR/YOD1/PRKN/SVIP/UBE2J1/RNF5/BAG6/TRIM13/BAG6/BAG6/BAG6/BAG6/FBXO17 41
GO:1903533 regulation of protein targeting 31/3662 74/15509 0.000371231 0.00203079 0.00122128 CSNK2A2/LMAN1/SH3GLB1/PDCD5/GSK3A/RAC2/PRKAA1/SAE1/BAG3/DMTN/ITGB2/BAP1/CDK5/MFF/ITGAM/HRAS/PDZK1/ATG13/CDK5R1/MIEF2/CIB1/PRKN/UBE2L3/UBL5/GDI1/HSPA1L/HSPA1L/FIS1/HSPA1L/HSPA1L/HSPA1L 31
GO:0007052 mitotic spindle organization 44/3662 116/15509 0.00037741 0.00206096 0.00123942 SPAST/PARP3/EML1/RHOA/SMC1A/NDC80/PIBF1/CHMP5/TPX2/BIRC5/NUDC/KIF4A/MYBL2/CHMP4B/RAB11A/ARHGEF10/BCCIP/SMC3/CDC20/STMN1/PTPA/SBDS/CHMP1A/CCNB1/PSRC1/CDCA8/BORA/NUMA1/KIF23/CENPE/PLK2/SPC25/PCNT/MAP9/VCP/GOLGA2/CHMP6/AURKB/CHEK2/DRG1/KIFC1/LSM14A/TBCE/SPICE1 44
GO:2000779 regulation of double-strand break repair 44/3662 116/15509 0.00037741 0.00206096 0.00123942 KDM1A/PARP3/ARID1B/RAD51/ACTB/SIRT6/FUS/BCL7C/SMARCB1/TFIP11/RBBP8/RECQL5/SMARCD2/NSD2/BCL7A/FOXM1/ARID1A/SLF2/SHLD2/MORF4L2/DEK/YEATS4/AUNIP/POT1/EPC2/ACTR2/PARP1/RADX/PPP4C/HMGA2/MRNIP/BRD7/RNF169/NUDT16L1/MGMT/KAT5/RMI2/MAGEF1/SETD2/ARID2/TRRAP/PRKDC/RTEL1/SMARCB1 44
GO:0003205 cardiac chamber development 55/3662 153/15509 0.000379191 0.00206886 0.00124418 PKP2/PRDM1/FGFR2/NDST1/LRP2/ZMPSTE24/FKBP1A/HECTD1/DSP/BMP7/SMAD7/NPRL3/TGFB1/GSK3A/TGFBR1/ENG/GATA3/BMPR1A/NSD2/NPHP3/WNT5A/HES1/SNX17/FHL2/TNNT2/NRP2/TEK/SOX4/BMP2/TNNI3/NOTCH2/SMAD6/IGF1R/GREB1L/SMAD4/CCN1/SLIT2/ANK2/NOTCH1/POU4F1/ADAMTS1/TNNI1/MAML1/RBM15/TGFBR2/HEYL/NOS3/FRS2/DCTN5/RBPJ/ZFPM2/NKX2-5/NOG/SLIT3/PARVA 55
GO:0043467 regulation of generation of precursor metabolites and energy 47/3662 126/15509 0.000379587 0.0020692 0.00124438 SLC4A1/IGF1/RHOA/SIRT6/GSK3B/P2RX7/GSK3A/PPIF/IFNG/IL4/PASK/PARK7/PPP1R3C/SLC25A23/TRAP1/DYRK2/CBFA2T3/PRKAA1/CCNB1/ISCU/KHK/COX17/APP/ARNT/OGT/SLC2A6/AK4/VCP/GPD1/DDIT4/PRELID1/CDK1/PGAM1/SLC25A33/PDE12/PHLDA2/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/EIF6/IL10RB 47
GO:0033044 regulation of chromosome organization 74/3662 219/15509 0.000380767 0.00207381 0.00124715 CDC27/UPF1/BAZ1B/ARID1B/RNF4/SMG6/ACTB/SIRT6/XRCC5/NDC80/ATRX/ZW10/MAPKAPK5/ANAPC5/BIRC5/HNRNPC/CDC6/BCL7C/SMARCB1/ACTR5/NBN/SMARCD2/BCL7A/FBXO5/RAD50/MACROH2A1/SMC4/XRN1/KAT2B/INO80D/CDC20/ARID1A/SLF2/TEX14/BECN1/POT1/DNMT1/DKC1/TOP2A/CCNB1/PPHLN1/CDCA8/APC/HNRNPA1/CCT7/NUMA1/CENPE/NABP2/RB1/PIF1/PARP1/SPC25/SMARCA5/TAL1/H3-3A/BRD7/CCT2/BUB1/EXOSC10/DCP2/KAT5/LIG4/ZWILCH/RMI2/AURKB/MAPK15/USP7/ARID2/SRC/SMG5/TEN1/RTEL1/SMARCB1/TINF2 74
GO:0045646 regulation of erythrocyte differentiation 20/3662 41/15509 0.000381845 0.00207515 0.00124796 SPI1/GATA1/HOXA5/MAPK14/HSPA9/STAT1/FOXO3/INHBA/PRMT1/ZFP36/ABCB10/ARNT/TAL1/INPP5D/STAT5B/ZFP36L1/MAFB/PRKDC/B2M/INPP5D 20
GO:0010226 response to lithium ion 13/3662 22/15509 0.000382353 0.00207515 0.00124796 CDH1/GSK3A/IGFBP2/PTK2B/IMPA2/PKLR/SHH/ADCY1/ARL13B/LIG4/CALR/CEBPA/PKLR 13
GO:0034104 negative regulation of tissue remodeling 13/3662 22/15509 0.000382353 0.00207515 0.00124796 CD38/P2RX7/CSK/SFRP1/HAMP/CALCA/TNFAIP3/IAPP/IL6/TNFRSF11B/INPP5D/GPR137/INPP5D 13
GO:1903799 negative regulation of miRNA maturation 13/3662 22/15509 0.000382353 0.00207515 0.00124796 ZMPSTE24/ESR1/TGFB1/IL6/TERT/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 13
GO:0001707 mesoderm formation 30/3662 71/15509 0.000384242 0.00208358 0.00125303 HOXA11/ITGA3/FGFR2/PRKACA/ITGA8/BMP7/AXIN1/EYA1/GPI/BMPR1A/DKK1/WNT3/WNT5A/INHBA/TWSG1/ARMC5/EPHA2/HMGA2/ITGB1/GJA1/NODAL/SMAD2/NOG/NF2/TXNRD1/ITGB3/WNT3/WNT3/GPI/PRKACA 30
GO:0060606 tube closure 36/3662 90/15509 0.000386117 0.00209192 0.00125804 PRKACA/TULP3/LRP2/TMED2/KDM2B/HECTD1/ABL1/CECR2/MTHFD1/TSC2/SFRP1/TGFB1/DVL1/FOLR1/NPHP3/WNT5A/MTHFD1L/RARA/BBS4/SKI/ARHGAP35/DVL3/VANGL2/CASP3/SEMA4C/RARG/GLMN/SETD2/RGMA/NOG/BRD2/BRD2/BRD2/BRD2/BRD2/PRKACA 36
GO:0110053 regulation of actin filament organization 81/3662 244/15509 0.000391441 0.00211891 0.00127428 SCIN/CYFIP2/RHOA/ROCK1/SPTB/CDC42/WDR1/ARHGEF10L/ADD2/ACTN2/ADD1/PXN/ABL1/HCK/COTL1/PYCARD/TJP1/SFRP1/ARHGEF10/MTPN/MET/TGFBR1/CXCL12/CSF3/ARPC3/DBN1/CAPZA1/STMN1/PTK2B/DSTN/ID1/CCR7/CDC42EP1/ARPC1B/PPFIA1/WASF3/DBNL/CCL21/RDX/ABI2/BBS4/SLIT2/PIK3R1/ARHGAP18/C9orf72/GSN/CDC42EP2/PLEKHH2/DMTN/ARHGAP35/SPTBN4/ALOX15/WNT4/ARPC5/CDC42EP3/SPTA1/PRKCD/ARFIP1/RICTOR/TTC8/S1PR1/PRKCE/CCL11/SPTBN2/FLII/GRB2/PAK2/PRKN/NF2/CD47/GMFB/SPTAN1/MTOR/IQANK1/TMSB4X/PDXP/ARPC1A/TWF2/SHANK3/BRK1/TJP1 81
GO:0045685 regulation of glial cell differentiation 29/3662 68/15509 0.000396164 0.0021426 0.00128852 TMEM98/TNFRSF1B/KDM4A/WDR1/TP73/TGFB1/PTN/MDK/HES1/ID2/HDAC1/CXCR4/EGR2/NKX2-2/BMP2/NR1D1/LIF/SERPINE2/IL6/DUSP10/TNFRSF21/NOTCH1/SHH/CDK1/DAG1/F2/NOG/CNTN2/MTOR 29
GO:0035305 negative regulation of dephosphorylation 21/3662 44/15509 0.00040075 0.00216552 0.0013023 ROCK1/GSK3B/PPP1R15A/FKBP1A/PPP1R16B/URI1/PTPA/MASTL/CRY2/STYXL1/ENSA/BOD1/TNF/PPP1R11/TNF/TNF/TNF/TNF/TNF/TNF/TNF 21
GO:1903556 negative regulation of tumor necrosis factor superfamily cytokine production 28/3662 65/15509 0.000406652 0.00219497 0.00132002 LTF/IGF1/FOXP3/ARG2/ACP5/LILRB1/IL27RA/CD33/IL4/TNFAIP3/RARA/SYT11/PTPN22/IL10/TLR4/ARRB2/NOD2/LGALS9/ADIPOQ/LILRB4/ORM1/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 28
GO:0048525 negative regulation of viral process 35/3662 87/15509 0.000406909 0.00219497 0.00132002 LTF/EIF2AK2/MID2/MAVS/N4BP1/TRIM14/AICDA/STAT1/TRIM25/ZFP36/TRIM5/SRPK2/GSN/HMGA2/MBL2/TRIM8/LARP7/BANF1/CIITA/IFITM1/HEXIM1/PLSCR1/PPIA/TNF/TRIM13/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TRIM26/CCL5/CCL5 35
GO:0035270 endocrine system development 46/3662 123/15509 0.000407341 0.00219539 0.00132027 BAD/BAK1/CDH1/PITX1/GLI2/RAP1GAP/GSK3B/GSK3A/HOXA5/TGFBR1/GATA3/BMPR1A/MDK/WNT5A/HES1/CRHR1/SOX4/NKX2-2/BMP2/THRA/HOXD3/ALDH1A2/MNX1/MEN1/PDGFRA/IL6/NKX2-1/CYP1B1/FGF2/ARMC5/SMAD4/ARID5B/BMP6/IL6R/WNT4/INHBB/PITX2/SHH/RBPJ/CDH2/EIF2AK3/SMAD2/NKX2-5/NOG/POU3F2/PBX1 46
GO:0032703 negative regulation of interleukin-2 production 16/3662 30/15509 0.000408685 0.00219938 0.00132267 FOXP3/NAV3/TBX21/PTPRC/GATA3/TNFAIP3/ZFP36/SFTPD/NOD2/KAT5/LILRB4/CR1/PTPRC/LILRB4/LILRB4/LILRB4 16
GO:0048863 stem cell differentiation 75/3662 223/15509 0.000408791 0.00219938 0.00132267 UFL1/SNAI2/EIF2AK2/FGFR2/CDC42/MBD3/TP63/SIRT6/XRCC5/PTPRC/GSK3B/ESR1/ABL1/OSM/BMP7/RBBP7/SETD6/SFRP1/ERCC2/PTN/EZH2/BMPR1A/WNT3/FOLR1/CORO1C/SH2B3/CHD4/MAPK14/HSPA9/FAM172A/HES1/FN1/KDM3A/HDAC1/NRP2/PHF19/RUNX2/ZFP36/LIF/ALDH1A2/LAMA5/PDGFRA/EDNRB/FGF2/SMAD4/NOTCH1/HMGA2/ITGB1/ZFP36L2/KIT/RBBP4/FRZB/PITX2/SHH/CDK12/GATAD2A/RBPJ/SEMA4C/HOXD4/SEMA3E/CDH2/KAT5/A2M/SETD2/NKX2-5/NOG/FOXO4/NELFB/PDCD6/PRKDC/PTPRC/WNT3/WNT3/LRP6/ITCH 75
GO:0051216 cartilage development 63/3662 181/15509 0.000412474 0.00221727 0.00133343 HOXA11/SCIN/SNAI2/RUNX3/CD44/BARX2/HYAL2/FGFR3/PITX1/ZMPSTE24/GLG1/BMP7/SMAD7/SLC39A14/TGFB1/HOXA5/TGFBR1/BMPR1A/ZBTB16/MDK/WNT5B/MAPK14/SMAD5/WNT5A/PRRX1/SNX19/RUNX2/BMP2/THRA/HOXD3/TWSG1/RARA/CHI3L1/LOXL2/ADAMTS7/CCN3/FGF2/COL2A1/RB1/CCN1/ZEB1/SERPINH1/HMGA2/BMP6/STC1/RUNX1/FRZB/TGFBR2/BMP1/EIF2AK3/RARG/ESRRA/LEP/TYMS/MAF/PTPN11/CREB3L2/RFLNB/NOG/WNT7B/COL27A1/COL11A2/LOC102724560 63
GO:0030521 androgen receptor signaling pathway 22/3662 47/15509 0.000413966 0.00222144 0.00133593 KDM1A/RNF14/PLPP1/RHOA/PIAS2/SFRP1/ZMIZ1/DDX5/KDM3A/PARK7/HDAC1/ARID1A/PKN1/NODAL/PRMT2/HEYL/TRIM68/DAXX/DAXX/DAXX/DAXX/DAXX 22
GO:0060964 regulation of miRNA-mediated gene silencing 22/3662 47/15509 0.000413966 0.00222144 0.00133593 PUM2/ELAVL1/ZMPSTE24/ESR1/TGFB1/DDX5/ZFP36/AJUBA/MYCN/IL6/EGFR/TERT/TRUB1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 22
GO:0003279 cardiac septum development 39/3662 100/15509 0.000415062 0.0022229 0.00133681 PRDM1/FGFR2/NDST1/LRP2/HECTD1/BMP7/SMAD7/NPRL3/TGFBR1/ENG/GATA3/BMPR1A/NSD2/NPHP3/WNT5A/HES1/SNX17/NRP2/SOX4/NOTCH2/SMAD6/SMAD4/CCN1/SLIT2/ANK2/NOTCH1/MAML1/RBM15/TGFBR2/HEYL/NOS3/FRS2/DCTN5/RBPJ/ZFPM2/NKX2-5/NOG/SLIT3/PARVA 39
GO:0032835 glomerulus development 27/3662 62/15509 0.000415315 0.0022229 0.00133681 PROM1/NOTCH3/ANGPT2/PDGFB/BMP7/ACTA2/PDGFRB/HES1/TEK/EGR1/PODXL/FOXJ1/NOTCH2/PDGFRA/EDNRB/PLCE1/ENPEP/NOTCH1/IL6R/HEYL/LAMB2/ADIPOQ/NOG/MAGI2/ITGB3/PECAM1/CD24 27
GO:0061077 chaperone-mediated protein folding 27/3662 62/15509 0.000415315 0.0022229 0.00133681 CD74/HSPA5/FKBP1A/PDCD5/DNAJB6/HSPB1/BAG1/HSPA8/CHORDC1/HSPA9/PDCL3/HSPE1/P3H1/CLU/TRAP1/HSPA2/CCT7/DNAJB12/PDIA4/PEX19/CCT2/HSPA1L/HSPA1L/HSPA1L/HSPA1L/HSPA1L/CHORDC1 27
GO:0000819 sister chromatid segregation 67/3662 195/15509 0.000417162 0.00223086 0.0013416 CDC27/BAZ1B/ARID1B/SMC1A/ACTB/SPAG5/NDC80/PIBF1/ATRX/SEH1L/CHMP5/ZW10/ANAPC5/BIRC5/NUDC/KIF4A/CDC6/BCL7C/SMARCB1/CHMP4B/RAB11A/SMC3/SMARCD2/BCL7A/FBXO5/MACROH2A1/SMC4/KAT2B/CDC20/NSL1/ARID1A/SLF2/TEX14/NAA50/PDS5A/CENPK/BECN1/MAU2/CHMP1A/TOP2A/CCNB1/PSRC1/CDCA8/APC/NUMA1/NUSAP1/KIF23/CENPE/RB1/KIF2C/CENPC/BOD1/NCAPG2/SPC25/SMARCA5/BRD7/BUB1/KAT5/ZWILCH/RMI2/CHMP6/AURKB/MAPK15/KMT5A/ARID2/KIFC1/SMARCB1 67
GO:0090066 regulation of anatomical structure size 142/3662 468/15509 0.000418389 0.00223549 0.00134439 CD38/KDM1A/USH1C/IFRD1/SCIN/PAFAH1B1/CPS1/CASR/CDH1/CYFIP2/NTN1/RHOA/ROCK1/SPTB/WDR1/PICALM/ADD2/ACTN2/GSK3B/PPP1R15A/MMP2/ADD1/P2RX7/DPYSL2/HSP90AB1/ABL1/CDHR5/ADNP/HCK/COTL1/PYCARD/RAB11A/KCNN4/KXD1/MTPN/CXCL12/ACTA2/CSF3/WNT3/CALCA/ARPC3/PPARD/DBN1/WNT5A/TTL/FN1/CAPZA1/SPP1/PTK2B/DSTN/CCR7/HP1BP3/CDC42EP1/APOE/ARPC1B/PER2/NGF/EDNRB/DBNL/CCL21/KIAA0319/RDX/BBS4/SOD1/CRABP2/SNAPIN/SLIT2/ARHGAP18/SLC12A9/MSN/GSN/CDC42EP2/POU4F2/PLEKHH2/DMTN/ARHGAP35/SPTBN4/AP2M1/ALOX15/ARPC5/DISC1/CDC42EP3/SPTA1/PRKCD/RICTOR/GPER1/NOS3/CDK5/BORCS7/SEMA4C/ADRB2/SEMA3E/PRKCE/LPAR3/FGG/FGA/CCL11/RARG/SPTBN2/LEP/ZDHHC21/BDNF/FLII/GRB2/CDH4/OXTR/F2R/NPM1/SLC8A1/CNTN2/ADRA2C/DCC/WNT7B/LAMTOR4/CLN3/ABCB8/SPTAN1/MTOR/IQANK1/GDI1/TNF/AKT1S1/TMSB4X/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PDXP/ARPC1A/HBB/TWF2/SHANK3/BRK1/LOC102724560/AKT3/NEFL/WNT3/WNT3/PTEN 142
GO:0048016 inositol phosphate-mediated signaling 26/3662 59/15509 0.000421707 0.00224283 0.0013488 PTBP1/IGF1/ATP2B4/ERBB3/INPP5A/GSK3B/NFATC2/NFAT5/PPP3CB/FHL2/DYRK2/PLCE1/ITPR1/SPPL3/CHP2/CIB1/MTOR/TNF/TNF/STIMATE/TNF/TNF/TNF/TNF/TNF/TNF 26
GO:0007566 embryo implantation 23/3662 50/15509 0.000422062 0.00224283 0.0013488 VMP1/FBLN1/MMP2/MMP9/SYDE1/C1QBP/CALCA/PPARD/SPP1/RECK/IL1B/LIF/EPO/SOD1/GJA1/NODAL/STC1/H3-3A/TGFBR2/BSG/CALR/YTHDF3/ITGB3 23
GO:0019083 viral transcription 23/3662 50/15509 0.000422062 0.00224283 0.0013488 MID2/SMARCB1/MON1B/USF2/TRIM14/HDAC1/TARDBP/ZFP36/MDFIC/TARBP2/HMGA2/PSMC3/TRIM8/LARP7/JUN/HEXIM1/TRIM13/CCL5/CCL5/CCL4/CCL4/SMARCB1/CCL4 23
GO:0060966 regulation of gene silencing by RNA 23/3662 50/15509 0.000422062 0.00224283 0.0013488 PUM2/ELAVL1/ZMPSTE24/ESR1/TGFB1/DDX5/ZFP36/AJUBA/MYCN/IL6/TARBP2/EGFR/TERT/TRUB1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 23
GO:2000059 negative regulation of ubiquitin-dependent protein catabolic process 23/3662 50/15509 0.000422062 0.00224283 0.0013488 HFE/HIPK2/CSNK2A2/BAG6/HSP90AB1/USP14/N4BP1/SGTA/PDCL3/PARK7/USP9X/TLK2/OGT/EIF3H/RYBP/SHH/USP7/SVIP/BAG6/BAG6/BAG6/BAG6/BAG6 23
GO:0006605 protein targeting 92/3662 284/15509 0.000422257 0.00224283 0.0013488 AGK/ZDHHC6/TOMM34/HSPA5/HERPUD1/SEC61A1/AP3D1/SEC61A2/CSNK2A2/LMAN1/BAG6/SH3GLB1/TIMM13/RNF215/MICALL1/SAMM50/AP4S1/TIMM9/CHMP4B/UBL4A/MON1B/SGTA/PDCD5/GSK3A/GRPEL1/HSPA8/MAN1A1/PEX7/ARL6/SPCS1/TRAK2/MFN2/CLU/BECN1/ATG14/RAB3IP/RAC2/HACL1/TIMM10B/PRKAA1/AP3B1/ZDHHC4/SORL1/SRP14/SAE1/SRPRB/PARD3/IMMP1L/TIMM8B/BAG3/ZFAND2B/DMTN/ITGB2/ZDHHC12/PEX19/ZDHHC3/BAP1/CDK5/SRP68/MFF/ITGAM/TOMM20/HRAS/PDZK1/ATG13/TOMM5/ZDHHC21/CDK5R1/MIEF2/TRAK1/AP3M1/CIB1/PRKN/HGS/UBE2L3/NACA/UBL5/RASSF9/GDI1/ZDHHC18/HSPA1L/BAG6/HSPA1L/FIS1/HSPA1L/BAG6/BAG6/BAG6/HSPA1L/BAG6/HSPA1L/TIMM23 92
GO:0016573 histone acetylation 56/3662 157/15509 0.000422295 0.00224283 0.0013488 NFYA/KMT2E/MED24/BAZ1B/SNAI2/FOXP3/NFYC/SPI1/MBD3/ACTB/ZMPSTE24/ATXN7L3/BRPF3/SMARCB1/JADE3/GATA3/NAA40/ZNF451/KAT2B/SF3B1/PARK7/DR1/NAA50/MORF4L2/DEK/YEATS4/LIF/MYBBP1A/WBP2/TAF5L/EPC2/IRF4/BRCA2/SMAD4/OGT/KAT14/MBIP/SMARCA5/BRPF1/CTBP1/TAF6L/PYGO2/BRD7/SETD5/TADA3/HCFC1/KAT5/MSL2/TAF7/MUC1/NOC2L/WDR5/TRRAP/SMARCB1/TADA2A/PCGF2 56
GO:0045428 regulation of nitric oxide biosynthetic process 25/3662 56/15509 0.000425333 0.00225676 0.00135718 ATP2B4/HSP90AB1/ACP5/IFNG/PKD2/CLU/PTK2B/IL1B/ASS1/CD36/IL10/TLR4/DDAH1/CX3CR1/TRPV1/CD47/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HBB 25
GO:0097720 calcineurin-mediated signaling 24/3662 53/15509 0.000425647 0.00225676 0.00135718 PTBP1/IGF1/ATP2B4/ERBB3/GSK3B/NFATC2/NFAT5/PPP3CB/FHL2/NR5A2/DYRK2/SPPL3/CHP2/CIB1/MTOR/TNF/TNF/STIMATE/TNF/TNF/TNF/TNF/TNF/TNF 24
GO:0002244 hematopoietic progenitor cell differentiation 45/3662 120/15509 0.000436929 0.00231262 0.00139077 UFL1/FLT4/EIF2AK2/SPI1/EML1/HYAL2/XRCC5/PTPRC/ABL1/OSM/FLT1/SFRP1/ERCC2/TGFB1/ARMC6/ZNHIT1/GATA3/SH2B3/BVES/ZBTB24/HSPA9/HES1/MYB/FLT3/INHBA/SOX4/SBDS/ZFP36/KDR/TOP2A/RARA/AP3B1/PDGFRA/NOTCH1/AGPAT5/KIT/SHH/KAT5/LIG4/CSF1R/CEBPD/TNFRSF13B/PRKDC/PTPRC/ITCH 45
GO:2000278 regulation of DNA biosynthetic process 45/3662 120/15509 0.000436929 0.00231262 0.00139077 HGF/PARP3/SMG6/XRCC5/NOX4/MAPKAPK5/HNRNPC/HSP90AB1/PDGFB/GINS1/JADE3/PRKD2/SMOC2/PDGFRB/XRN1/PTK2B/CDKN1A/POT1/DKC1/MEN1/HNRNPA1/CCT7/CYP1B1/FGF2/PIF1/ARRB2/CCT2/EXOSC10/DCP2/AURKB/MAPK15/ADIPOQ/SRC/TFDP1/SMG5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TEN1/TINF2 45
GO:0045995 regulation of embryonic development 33/3662 81/15509 0.000449234 0.0023737 0.0014275 PAFAH1B1/LAMA3/RPS6KA6/BAG6/LAMA1/NPHP3/KAT2B/HES1/INO80D/DR1/TGIF2/LAMA5/TDG/NOTCH1/KAT14/MBIP/NODAL/B4GALT5/WNT4/POGLUT1/CDK1/TADA3/CFL1/DAG1/PHLDA2/PLCB1/WDR5/BAG6/BAG6/BAG6/BAG6/BAG6/TADA2A 33
GO:1901992 positive regulation of mitotic cell cycle phase transition 33/3662 81/15509 0.000449234 0.0023737 0.0014275 CDC27/KMT2E/ANAPC5/CDC6/CDC7/APEX1/CDC25B/RAB11A/CCND1/FBXO5/CCND3/HSPA2/CCNB1/RDX/RB1/CUL4A/CYP1A1/APP/DTL/EGFR/ADAMTS1/LSM11/CUL4B/DBF4B/TERT/RRM1/CDK1/RRM2/RCC2/PLCB1/CDK10/PBX1/TFDP1 33
GO:0009411 response to UV 50/3662 137/15509 0.000456903 0.00241217 0.00145064 KDM1A/BAK1/USP28/TMEM161A/HYAL2/SIRT6/UBE2A/BAX/MMP2/MSH2/CIRBP/MMP9/ACTR5/N4BP1/ERCC2/MAPK8/CCND1/IL12B/CAT/CDKN1A/PRKAA1/MEN1/DDB2/XPA/BRCA2/CUL4A/DTL/PARP1/PIK3R1/EGFR/XPC/CUL4B/BRSK1/RPL26/ERCC3/PRKCD/UVSSA/CASP3/TP53INP1/TRIAP1/RHNO1/RELA/AURKB/NPM1/H2AC25/NOC2L/MME/MMP1/ELANE/ELANE 50
GO:0002726 positive regulation of T cell cytokine production 17/3662 33/15509 0.000463262 0.00243537 0.00146459 TBX21/GATA3/CD81/IL4/IL1B/IL6/IL18/CD55/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/B2M 17
GO:0032743 positive regulation of interleukin-2 production 17/3662 33/15509 0.000463262 0.00243537 0.00146459 CD4/PTPRC/ABL1/PRKD2/PDE4D/CD86/IL1A/CD80/IL1B/IRF4/RUNX1/STAT5B/GLMN/CD28/PDE4B/PNP/PTPRC 17
GO:0045940 positive regulation of steroid metabolic process 17/3662 33/15509 0.000463262 0.00243537 0.00146459 IFNG/IL1A/NR1D1/APOE/PRKAA1/IGF1R/BMP6/LDLRAP1/WNT4/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 17
GO:1903203 regulation of oxidative stress-induced neuron death 17/3662 33/15509 0.000463262 0.00243537 0.00146459 PARK7/NR4A3/IL10/TLR4/MEAK7/PARP1/NONO/TBC1D24/PRKN/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 17
GO:2000515 negative regulation of CD4-positive, alpha-beta T cell activation 17/3662 33/15509 0.000463262 0.00243537 0.00146459 RUNX3/FOXP3/CBFB/TBX21/IL4R/ARG2/SMAD7/JAK3/IL4/BCL6/TWSG1/NDFIP1/HLX/RUNX1/LGALS9/HMGB1/ITCH 17
GO:0019080 viral gene expression 37/3662 94/15509 0.000467649 0.00245635 0.0014772 ST3GAL1/PTBP1/ST6GAL1/MID2/GSK3B/SMARCB1/MON1B/USF2/GSK3A/EIF3B/TRIM14/EIF3A/SPCS1/HDAC1/TARDBP/PRMT1/ZFP36/MDFIC/ST6GALNAC4/TARBP2/FURIN/HMGA2/ST3GAL2/PSMC3/TRIM8/LARP7/JUN/ST6GALNAC3/HEXIM1/PCBP2/TRIM13/CCL5/CCL5/CCL4/CCL4/SMARCB1/CCL4 37
GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation 10/3662 15/15509 0.000483147 0.00252704 0.00151972 FOXP3/IFNG/IL2RG/LGALS9/KLHL25/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA/HLA-DRA 10
GO:0031652 positive regulation of heat generation 10/3662 15/15509 0.000483147 0.00252704 0.00151972 IL1B/TNFRSF11A/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 10
GO:0032819 positive regulation of natural killer cell proliferation 10/3662 15/15509 0.000483147 0.00252704 0.00151972 IL12B/IL18/STAT5B/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E/HLA-E 10
GO:0071871 response to epinephrine 10/3662 15/15509 0.000483147 0.00252704 0.00151972 KCNQ1/ATP2B4/SIRT2/PRKACA/ABL1/PKLR/ADIPOQ/PDE4B/PKLR/PRKACA 10
GO:1903960 negative regulation of anion transmembrane transport 10/3662 15/15509 0.000483147 0.00252704 0.00151972 ARL6IP5/SLC43A2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 10
GO:1903209 positive regulation of oxidative stress-induced cell death 14/3662 25/15509 0.000487809 0.00254862 0.0015327 NOX1/ABL1/PARK7/FOXO3/TLR4/SOD1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 14
GO:0006397 mRNA processing 129/3662 421/15509 0.000488095 0.00254862 0.0015327 KDM1A/PAF1/PTBP1/ZCCHC8/THOC3/SNRNP40/DDX20/PHRF1/DAZAP1/FAM50A/PRKACA/MBNL3/DDX1/SF3B2/XRN2/RBM41/RBM27/ALKBH5/HNRNPC/CWF19L1/CIRBP/SNRPD3/TFIP11/SNU13/RBFOX2/ZC3H14/ACIN1/PABPN1/PNN/CSTF1/PRPF6/CSTF2/ESRP1/SNRNP70/YJU2/CASC3/C1QBP/DDX5/EFTUD2/ZPR1/HSPA8/AICDA/SRSF9/FAM172A/NCL/PAPOLG/SF3B1/SRSF7/SRSF4/PRPF3/PTBP2/PRDX6/PTBP3/NRDE2/TARDBP/COIL/SMU1/SNRPC/RNF113A/HNRNPR/RALY/RBM42/SCAF1/PUS7L/AAR2/GRSF1/PRMT7/RBM17/SRPK2/HNRNPA1/SRSF1/PRPF4/NCBP1/CMTR1/SLTM/DBR1/CIR1/SCAF11/SNRPF/DHX38/EIF4A3/APP/SF3B4/SNRPG/POLR2D/WTAP/LUC7L2/NONO/RBMX/CWC15/MBNL1/CWC27/LSM11/SCAF4/SSU72/RBM15/THOC7/RPUSD4/TRUB1/CPSF2/SNRPD1/CDK12/SRRM2/SNRNP48/AHCYL1/USP39/HNRNPH1/ZRSR2/HNRNPA3/SMN1/CLP1/LARP7/PDE12/AURKAIP1/PUS1/ERN1/NPM1/RBM10/ZFP36L1/RNPC3/UBL5/LSM2/RBM15B/SRSF8/RBM8A/SRSF1/PRPF8/RBM27/PRKACA 129
GO:0042177 negative regulation of protein catabolic process 40/3662 104/15509 0.00049155 0.00256346 0.00154162 HFE/CTSA/ROCK1/SIRT2/VPS35/BAG6/HSP90AB1/USP14/N4BP1/SNRNP70/SGTA/PARK7/USP9X/PIN1/MGAT3/SERPINE2/IL10/FURIN/SMAD4/EGFR/TLK2/OGT/SNX12/EIF3H/ALAD/USP25/RYBP/SHH/RELA/NQO1/ADGRB1/ANXA2/USP7/SVIP/BAG6/BAG6/BAG6/BAG6/BAG6/F8A1 40
GO:0001959 regulation of cytokine-mediated signaling pathway 49/3662 134/15509 0.000492178 0.00256346 0.00154162 PAFAH1B1/CD74/UBE2K/PTPRC/MAVS/BIRC7/PYCARD/IL7/HPX/SH2B3/WNT5A/PADI2/TNFAIP3/ARG1/CXCR4/H2BC11/RNF113A/IRF3/PXDN/IL6/IL1RN/SLIT2/GFI1/SYK/TRIM44/FADD/NKIRAS2/TRIM56/PTPN2/PTPN11/ADIPOQ/TRAIP/IRAK1/SLIT3/CSF1/SIGIRR/SOCS1/PRKN/YTHDF3/NKIRAS1/CPNE1/NAIP/LSM14A/PTPRC/CCL5/CD24/CCL5/NAIP/NAIP 49
GO:0003158 endothelium development 49/3662 134/15509 0.000492178 0.00256346 0.00154162 FOXP3/TIE1/RHOA/ROCK1/ADD1/ICAM1/PPP1R16B/TJP1/PRKD2/MET/EDF1/RAPGEF1/PDE4D/CXCR4/IL1B/ID1/KDR/BTG1/EDNRB/CCM2/RDX/ITGAX/SMAD4/RHOB/MSN/NOTCH1/ZEB1/BMP6/STC1/RBPJ/S1PR1/ZDHHC21/PLCB1/COL18A1/CSNK2B/TNF/TNF/TNF/CSNK2B/CSNK2B/TNF/TNF/CSNK2B/TNF/TNF/TNF/CSNK2B/PECAM1/TJP1 49
GO:0022604 regulation of cell morphogenesis 90/3662 278/15509 0.000495719 0.00257974 0.00155141 PAFAH1B1/SPAG9/CD44/HEXB/PKP2/RHOA/CDC42/WDR1/MARK2/ST6GAL1/PLXNA2/FBLN1/ZMPSTE24/SLC23A2/ABL1/MYH9/HCK/OLFM4/MYH14/DVL1/C1QBP/CCL2/SH3D19/MDK/CORO1C/NEDD9/BVES/DBN1/WNT5A/FN1/MPL/GNA13/PTK2B/CXCR4/OBSL1/KDR/CDC42EP1/RAC2/WASF3/EPHB2/DBNL/RDX/ACTR2/SYT2/RHOB/ARHGAP18/GNA12/MSN/GAS2/CDC42EP2/KIT/DMTN/EPB41/ARHGAP35/ITGB2/DVL3/TBC1D24/CDC42EP3/SPTA1/MELTF/EPB42/RHOH/PTK2/LIMS1/SEMA3E/FGG/FGA/CCL11/CFL1/DAG1/FZD4/SYNE3/RCC2/CALR/F2/CSF1R/CNTN2/SS18L1/FMNL1/CIB1/PRKN/BRWD1/BCL9L/SPRY4/SRC/PARVA/GPRASP3/PRKDC/CUX1/ITGB3 90
GO:1903034 regulation of response to wounding 56/3662 158/15509 0.00050591 0.00263056 0.00158197 CD9/GRN/F7/MYLK/APOH/XBP1/PDGFB/FERMT1/PLAT/PTN/SERPINE1/ACTA2/MDK/SH2B3/SMOC2/HBEGF/SERPINC1/TNFAIP3/SPP1/CXCR4/APOE/EPHB2/PDGFRA/CD36/SERPINE2/IL10/KIAA0319/THBS1/FGF2/IGF1R/ADAMTS18/ITGB1/DMTN/WNT4/PRKCD/NOS3/PRDX2/PTK2/PRKCE/FGG/FGA/HRAS/F2/F2R/RGMA/ANXA2/MTOR/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PTEN 56
GO:0036475 neuron death in response to oxidative stress 18/3662 36/15509 0.000507952 0.00263455 0.00158437 PARK7/NR4A3/IL10/TLR4/MEAK7/PARP1/ARL6IP5/NONO/TBC1D24/PRKN/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 18
GO:0045954 positive regulation of natural killer cell mediated cytotoxicity 18/3662 36/15509 0.000507952 0.00263455 0.00158437 IL12B/CD160/NECTIN2/IL21/STAT5B/HLA-E/HLA-E/NCR3/HLA-E/NCR3/HLA-E/HLA-E/HLA-E/NCR3/HLA-E/NCR3/NCR3/NCR3 18
GO:1903715 regulation of aerobic respiration 18/3662 36/15509 0.000507952 0.00263455 0.00158437 RHOA/PPIF/PARK7/SLC25A23/CBFA2T3/ISCU/AK4/VCP/SLC25A33/PDE12/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 18
GO:0001890 placenta development 51/3662 141/15509 0.000514075 0.00266185 0.00160079 PRDM1/FGFR2/DAZAP1/TMED2/HECTD1/HSP90AB1/PDGFB/BMP7/PTN/DNAJB6/CYP27B1/VDR/PPARD/MAPK14/HES1/EPAS1/ASH1L/PKD2/SPP1/LIF/SOX15/MEN1/NOTCH2/ADAM19/IL10/SOD1/CCN1/ARNT/PARP1/EGFR/NODAL/STC1/PLCD3/RBM15/CSF2/HTRA1/RBPJ/PTK2/CEBPB/BSG/LEP/FOSL1/GRB2/SETD2/PHLDA2/ZFP36L1/EPOR/WNT7B/MME/ZNF568/CEBPA 51
GO:0035148 tube formation 51/3662 141/15509 0.000514075 0.00266185 0.00160079 SDCCAG8/FGFR2/PRKACA/TULP3/LRP2/TMED2/KDM2B/HECTD1/ABL1/CECR2/MTHFD1/BMP7/TSC2/SFRP1/TGFB1/DVL1/GATA3/FOLR1/NPHP3/WNT5A/MTHFD1L/SOX4/PODXL/RARA/FGF2/EGF/BBS4/NOTCH1/BCL2L11/NODAL/SKI/ARHGAP35/DVL3/WNT4/VANGL2/CASP3/SHH/SEMA4C/RARG/GLMN/SETD2/RGMA/NOG/TGM2/BRD2/TCTN1/BRD2/BRD2/BRD2/BRD2/PRKACA 51
GO:0032200 telomere organization 58/3662 165/15509 0.000516025 0.00266972 0.00160552 UPF1/PARP3/RAD51/SP100/SIRT2/SMG6/SIRT6/XRCC5/ATRX/MAPKAPK5/HNRNPC/HSP90AB1/TFIP11/APEX1/NBN/DOT1L/CCNE1/EZH2/EZH1/RAD50/XRN1/INO80D/SLF2/SHLD2/POT1/DKC1/HNRNPA1/CCT7/SMARCAL1/NABP2/BRCA2/PIF1/PARP1/H3-3A/TERT/CCT2/EXOSC10/DCP2/CCNE2/AURKB/MAPK15/NOP10/USP7/SRC/DCLRE1A/SMG5/PRKDC/TEN1/RTEL1/H4C15/H4C14/H4C12/H3C6/H4C5/H4C4/H3C10/TINF2/H3C2 58
GO:0007051 spindle organization 60/3662 172/15509 0.000523352 0.00270537 0.00162696 SPAST/PARP3/RNF4/EML1/RHOA/SMC1A/MLH1/SPAG5/NDC80/PIBF1/ATRX/CHMP5/TPX2/BIRC5/NUDC/KIF4A/MYH9/MYBL2/CHMP4B/RAB11A/ARHGEF10/BCCIP/SMC3/FBXO5/CDC20/STMN1/PTPA/SBDS/AUNIP/CHMP1A/CCNB1/PSRC1/CDCA8/BORA/NUMA1/KIF23/HAUS2/CENPE/CSNK1D/PLK2/SPC25/PCNT/MAP9/VCP/MAPRE2/GOLGA2/RGS14/CHMP6/AURKB/MAPK15/CEP63/CHEK2/DRG1/TUBB/CCDC69/HAUS3/KIFC1/LSM14A/TBCE/SPICE1 60
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 48/3662 131/15509 0.000530049 0.0027377 0.00164641 HFE/RNF14/UFL1/HERPUD1/SIRT2/MKRN2/SIRT6/UBE2K/GSK3B/XPO1/HECTD1/BAG6/HSP90AB1/USP14/SMAD7/N4BP1/AXIN1/SGTA/GSK3A/DVL1/USP5/PARK7/CDC20/RAD23B/CLU/USP9X/CBFA2T3/HSPBP1/CSNK1D/GNA12/TLK2/OGT/EIF3H/RNF144A/RYBP/RCHY1/SHH/VCP/GLMN/PRKN/USP7/SVIP/BAG6/BAG6/BAG6/BAG6/BAG6/CEBPA 48
GO:0006620 post-translational protein targeting to endoplasmic reticulum membrane 12/3662 20/15509 0.000532029 0.0027388 0.00164707 HSPA5/SEC61A1/SEC61A2/BAG6/CHMP4B/UBL4A/SGTA/BAG6/BAG6/BAG6/BAG6/BAG6 12
GO:0046325 negative regulation of glucose import 12/3662 20/15509 0.000532029 0.0027388 0.00164707 SIRT6/GSK3A/PEA15/LEP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 12
GO:0060444 branching involved in mammary gland duct morphogenesis 12/3662 20/15509 0.000532029 0.0027388 0.00164707 PGR/ESR1/AREG/VDR/WNT5A/KDM5B/EPHA2/WNT4/BTRC/CCL11/CSF1/SRC 12
GO:0150078 positive regulation of neuroinflammatory response 12/3662 20/15509 0.000532029 0.0027388 0.00164707 CTSC/IL1B/IL6/IL18/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 12
GO:0022613 ribonucleoprotein complex biogenesis 122/3662 396/15509 0.000543155 0.00279375 0.00168011 TSR3/UTP18/RPL26L1/NOP16/EIF4B/DDX20/RRP15/BUD23/XRCC5/DDX1/XPO1/SF3B2/DDX18/XRN2/RPL6/AGO1/HSP90AB1/SNRPD3/PES1/SNU13/PRPF6/NOP56/RIOK3/PIN4/EIF3J/ERCC2/FBL/YJU2/DDX49/EIF3B/EIF4H/EXOSC3/EIF3A/C1QBP/NOP2/SRSF9/BRIX1/KAT2B/RRP9/SF3B1/PRPF3/EBNA1BP2/NSUN4/PTBP2/UTP20/COIL/SNRPC/EIF2S2/SBDS/DKC1/NOL11/AAR2/MYBBP1A/UTP3/ERAL1/PRMT7/SRPK2/LTV1/GLUL/MRPL44/SRSF1/NCBP1/SCAF11/SNRPF/TARBP2/CUL4A/PELP1/EIF4A3/METTL25B/ISG20L2/SF3B4/SNRPG/POLR2D/ABT1/RPL7L1/LUC7L2/RBMX/EIF3H/EIF3M/DHX37/HEATR3/CUL4B/TSR2/RPL26/NOL9/NSA2/DCAF13/RPL10L/RPUSD4/SNRPD1/USP39/ZRSR2/NMD3/MRPL1/PA2G4/RIOX2/MRPL36/EXOSC10/SMN1/CLP1/TRMT112/IMP3/NPM1/NOP10/RPS17/EIF3C/TRMT2B/NOC2L/RRP7A/RPL23A/SDAD1/RPL10A/LSM2/PWP2/EIF6/PRKDC/BOP1/SRSF1/PRPF8/AATF/PTEN/EMG1 122
GO:0030900 forebrain development 109/3662 348/15509 0.00054361 0.00279378 0.00168013 BAD/KDM1A/PAFAH1B1/TYROBP/UBA6/CDH1/PHLPP2/SYNE2/ATP2B4/FGFR2/RHOA/PITX1/NDST1/CSNK2A2/NDE1/GLI2/NOTCH3/PCM1/LRP2/GSK3B/ATRX/BAX/XRN2/KDM2B/RPGRIP1L/EZH2/AKNA/CXCL12/BMPR1A/DKK1/ZMIZ1/EZH1/MDK/WNT5A/HES1/ID2/HDAC1/SLC2A1/NRP2/CXCR4/INHBA/BMP2/BCL11B/TWSG1/ALDH1A2/RARA/EPHB2/KRAS/AKIRIN2/NKX2-1/ATAT1/FGF2/IGF1R/BBS4/APP/SLIT2/EPHA5/EGFR/NTRK2/NOTCH1/ZEB1/POU4F1/NR4A2/SKI/GART/BTG2/ARHGAP35/WNT4/ARPC5/DISC1/INHBB/PITX2/CASP3/SHH/CDK5/TTC8/FRS2/RBPJ/ARL13B/ITGAM/SEMA3E/CDH2/ALK/CNP/CDK5R1/SSTR2/OXTR/SETD2/CSF1R/EPHB3/PLCB1/SLC8A1/NOG/CNTN2/POU3F2/NF2/SECISBP2/WNT7B/H2AX/PAX5/PGAP1/SRC/TCTN1/CCDC85C/SHANK3/B2M/NDE1/NEFL/PTEN 109
GO:0002455 humoral immune response mediated by circulating immunoglobulin 28/3662 66/15509 0.000548865 0.00281611 0.00169356 FCGR2B/PTPRC/FCER2/C1QBP/HPX/CD81/CLU/C3/FOXJ1/MBL2/NOD2/ZP3/CD55/CR1/TNF/TNF/LTA/TNF/LTA/TNF/TNF/TNF/TNF/LTA/LTA/TNF/LTA/PTPRC 28
GO:0010822 positive regulation of mitochondrion organization 28/3662 66/15509 0.000548865 0.00281611 0.00169356 BAD/DCN/ZDHHC6/BAK1/VPS35/GSK3B/BAX/DNM1L/GZMB/MMP9/PYCARD/PDCD5/GSK3A/MAPK8/PPIF/PARK7/TNFSF10/KDR/HRK/NMT1/PMAIP1/BCL2L11/GPER1/MFF/MIEF2/PRKN/FIS1/PGAM5 28
GO:0046822 regulation of nucleocytoplasmic transport 38/3662 98/15509 0.000558207 0.00286168 0.00172096 CDH1/IPO5/SP100/HYAL2/PRKACA/SIRT6/GSK3B/XPO1/MAVS/HSP90AB1/RANGAP1/FERMT1/TGFB1/ZPR1/IFNG/MAPK14/PARK7/NRDE2/TARDBP/NUP153/IL1B/XPO4/CD36/MDFIC/ANP32B/PIK3R1/TCF7L2/BAG3/PRKCD/SHH/CDK5/CHP2/PKIG/CDK1/LEP/PTPN11/SETD2/PRKACA 38
GO:0010639 negative regulation of organelle organization 101/3662 319/15509 0.000564728 0.00288933 0.00173759 SCIN/BAZ1B/IGF1/HGF/BAK1/PHF23/NAV3/SPTB/SMG6/ADD2/NDC80/ATRX/ZW10/ADD1/TPX2/BIRC5/HNRNPC/TMEM14A/BMP7/CHMP4B/TSC2/NUBP1/TJP1/NBN/MTPN/MET/PPIF/FBXO5/RAD50/XRN1/KAT2B/CAPZA1/CDC20/STMN1/CLU/TEX14/IAPP/EML2/BECN1/STYXL1/LIF/POT1/BCL2L2/PPFIA1/TOP2A/CCNB1/CDCA8/APC/HNRNPA1/RDX/PIF1/BBS4/ARRB2/TBCD/SMAD4/PARP1/SLIT2/PIK3R1/GSN/SPC25/PLEKHH2/SMARCA5/DMTN/SPTBN4/LMNA/OMA1/H3-3A/SPTA1/PRKCD/FXN/PRELID1/BUB1/TRIAP1/S1PR1/BCL2L1/EXOSC10/DCP2/SPTBN2/ZWILCH/AURKAIP1/TMEM39A/FLII/AURKB/PAK2/NPM1/CIB1/INPP5J/CDK10/PRKN/FZD9/GMFB/SRC/SPTAN1/IQANK1/TMSB4X/TWF2/SHANK3/TEN1/RTEL1/TJP1/TINF2 101
GO:0032720 negative regulation of tumor necrosis factor production 27/3662 63/15509 0.000564999 0.00288933 0.00173759 IGF1/FOXP3/ARG2/ACP5/LILRB1/IL27RA/CD33/IL4/TNFAIP3/RARA/SYT11/PTPN22/IL10/TLR4/ARRB2/NOD2/LGALS9/ADIPOQ/LILRB4/ORM1/LILRB1/LILRB4/LILRB1/LILRB1/LILRB1/LILRB4/LILRB4 27
GO:0070918 small regulatory ncRNA processing 27/3662 63/15509 0.000564999 0.00288933 0.00173759 PUM2/TUT7/ZMPSTE24/ESR1/AGO1/ZC3H7B/TGFB1/DDX5/ZC3H7A/MYCN/IL6/NCBP1/TARBP2/EGFR/PUS10/TERT/TRUB1/SMAD2/SPOUT1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 27
GO:0045429 positive regulation of nitric oxide biosynthetic process 20/3662 42/15509 0.000568434 0.00289971 0.00174384 HSP90AB1/IFNG/PKD2/CLU/PTK2B/IL1B/ASS1/CD36/TLR4/DDAH1/TRPV1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/HBB 20
GO:0055010 ventricular cardiac muscle tissue morphogenesis 20/3662 42/15509 0.000568434 0.00289971 0.00174384 PKP2/FGFR2/LRP2/FKBP1A/DSP/SMAD7/TGFB1/TGFBR1/ENG/BMPR1A/TNNT2/TNNI3/SMAD4/NOTCH1/POU4F1/TNNI1/RBPJ/ZFPM2/NKX2-5/NOG 20
GO:2000403 positive regulation of lymphocyte migration 20/3662 42/15509 0.000568434 0.00289971 0.00174384 RHOA/ABL1/PYCARD/CXCL12/NEDD9/WNT5A/CCL20/ITGA4/PTK2B/CCL21/APP/ABL2/CXCL13/FADD/ITGB3/CCL5/CCL5/CCL4/CCL4/CCL4 20
GO:0044409 entry into host 52/3662 145/15509 0.000574857 0.00293007 0.00176209 CD4/CD74/HYAL2/MID2/ICAM1/KPNA3/SLC1A5/TRIM14/EFNB3/CD81/CD86/VAMP8/TRIM25/CD80/CXCR4/NUP153/NECTIN2/TRIM5/TRIM22/ITGAV/SLC7A1/FURIN/EPHA2/EGFR/GSN/NCAM1/ITGB1/CCR5/ANPEP/TRIM68/SLC3A2/LGALS9/CXCL8/GYPA/CDK1/TRIM8/BSG/DAG1/CIITA/EXOC7/SLC52A2/IFITM1/PLSCR1/HMGB1/CD55/SRC/DPP4/WWP2/CR1/TRIM26/ITGB3/ITCH 52
GO:0002407 dendritic cell chemotaxis 15/3662 28/15509 0.000581488 0.00294449 0.00177077 SPI1/PIK3CG/C1QBP/CXCR4/CCR7/CCL21/CCR5/CXCR1/LGALS9/CCL19/CALR/CXCR2/HMGB1/CCL5/CCL5 15
GO:0060149 negative regulation of post-transcriptional gene silencing 15/3662 28/15509 0.000581488 0.00294449 0.00177077 ELAVL1/ZMPSTE24/ESR1/TGFB1/IL6/TERT/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 15
GO:0060603 mammary gland duct morphogenesis 15/3662 28/15509 0.000581488 0.00294449 0.00177077 NTN1/FGFR2/PGR/ESR1/AREG/VDR/WNT5A/KDM5B/EPHA2/WNT4/BTRC/CCL11/CSF1R/CSF1/SRC 15
GO:0060965 negative regulation of miRNA-mediated gene silencing 15/3662 28/15509 0.000581488 0.00294449 0.00177077 ELAVL1/ZMPSTE24/ESR1/TGFB1/IL6/TERT/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 15
GO:0060967 negative regulation of gene silencing by RNA 15/3662 28/15509 0.000581488 0.00294449 0.00177077 ELAVL1/ZMPSTE24/ESR1/TGFB1/IL6/TERT/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 15
GO:0071353 cellular response to interleukin-4 15/3662 28/15509 0.000581488 0.00294449 0.00177077 HSPA5/IL4R/HSP90AB1/XBP1/JAK3/GATA3/ARG1/TUBA1B/IL2RG/ALAD/ADAMTS13/IL24/PTPN2/SHPK/ADAMTS13 15
GO:0072576 liver morphogenesis 15/3662 28/15509 0.000581488 0.00294449 0.00177077 XBP1/PTN/MDK/TNFAIP3/NOTCH2/IL6/CEBPB/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 15
GO:1900369 negative regulation of post-transcriptional gene silencing by RNA 15/3662 28/15509 0.000581488 0.00294449 0.00177077 ELAVL1/ZMPSTE24/ESR1/TGFB1/IL6/TERT/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 15
GO:0048013 ephrin receptor signaling pathway 22/3662 48/15509 0.00059533 0.00300232 0.00180555 EPHA3/EPHA8/EPHA6/MMP2/MMP9/EFNB3/CHN1/EPHB2/EPHA2/EPHA5/RBPJ/EFNA1/PTK2/CDK5R1/PTPN11/EPHB3/ANKS1B/SRC/SIPA1L1/NTRK1/EFNA4/EPHB6 22
GO:0050691 regulation of defense response to virus by host 22/3662 48/15509 0.00059533 0.00300232 0.00180555 MAVS/IL12RB1/PYCARD/LILRB1/IL12B/IL4/STAT1/TNFAIP3/IL1B/PTPN22/TARBP2/TRIM44/MICB/MICB/MICB/MICB/MICB/MICB/LILRB1/LILRB1/LILRB1/LILRB1 22
GO:1900368 regulation of post-transcriptional gene silencing by RNA 22/3662 48/15509 0.00059533 0.00300232 0.00180555 PUM2/ELAVL1/ZMPSTE24/ESR1/TGFB1/DDX5/ZFP36/AJUBA/MYCN/IL6/EGFR/TERT/TRUB1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/NEAT1 22
GO:1903747 regulation of establishment of protein localization to mitochondrion 22/3662 48/15509 0.00059533 0.00300232 0.00180555 CSNK2A2/LMAN1/SH3GLB1/GZMB/PDCD5/GSK3A/MAPK8/RAC2/PRKAA1/NMT1/SAE1/BAG3/BAP1/ATG13/PRKN/UBE2L3/UBL5/HSPA1L/HSPA1L/HSPA1L/HSPA1L/HSPA1L 22
GO:1905953 negative regulation of lipid localization 22/3662 48/15509 0.00059533 0.00300232 0.00180555 CRY1/NFKBIA/PPARD/CRY2/IL6/THBS1/ITGAV/EGF/SHH/LEP/PTPN2/PTPN11/TNF/TNF/FIS1/TNF/TNF/TNF/TNF/TNF/TNF/ITGB3 22
GO:0061028 establishment of endothelial barrier 24/3662 54/15509 0.000596291 0.00300473 0.00180699 FOXP3/ROCK1/ADD1/ICAM1/PPP1R16B/TJP1/RAPGEF1/PDE4D/IL1B/EDNRB/RDX/MSN/ZDHHC21/PLCB1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PECAM1/TJP1 24
GO:0007160 cell-matrix adhesion 70/3662 208/15509 0.000612272 0.00308275 0.00185391 ITGAL/ITGA3/ITGA2B/CD44/EPHA3/RHOA/ROCK1/ACTN2/ITGA8/GSK3B/CEACAM6/NID2/PXN/ABL1/FERMT1/MSLN/SFRP1/SERPINE1/CORO1C/BCL6/ITGA4/FN1/TEK/PTK2B/CCR7/RRAS/KDR/HOXD3/AJUBA/PPFIA1/TIMM10B/CD36/CCL21/TMEM8B/THBS1/ITGA11/ITGAV/ITGAX/PIK3R1/ITGB1/BCL2L11/CD96/MMP14/DMTN/ITGB2/ADAMTS13/WNT4/VCAM1/SNED1/DISC1/CDK5/ADAM9/PTK2/PLEKHA2/LIMS1/ITGAM/SEMA3E/FGG/FGA/DAG1/RCC2/CSF1/CIB1/NF2/BCAM/SRC/COL13A1/ITGB3/ADAMTS13/PTEN 70
GO:0070301 cellular response to hydrogen peroxide 32/3662 79/15509 0.000613802 0.0030853 0.00185544 HGF/ABL1/APEX1/MET/EZH2/PPIF/PARK7/TNFAIP3/ARG1/FOXO3/NR4A3/CAT/BECN1/TRAP1/PRKAA1/IL6/IL10/IL18BP/CYP1B1/RHOB/FABP1/PRKCD/FXN/CDK1/RELA/ERN1/NQO1/SRC/MAP3K5/ZNF277/ZNF580/PCGF2 32
GO:1901983 regulation of protein acetylation 32/3662 79/15509 0.000613802 0.0030853 0.00185544 NFYA/KMT2E/BAZ1B/SNAI2/FOXP3/NFYC/SPI1/GSK3B/ZMPSTE24/SMARCB1/GATA3/ZNF451/SF3B1/PARK7/SOX4/DEK/LIF/PRKAA1/MYBBP1A/WBP2/SMAD4/SMARCA5/CTBP1/PYGO2/BRD7/SETD5/KAT5/TAF7/MUC1/NOC2L/SMARCB1/TADA2A 32
GO:1903900 regulation of viral life cycle 46/3662 125/15509 0.000614272 0.0030853 0.00185544 CD4/LTF/CD74/EIF2AK2/MID2/MAVS/N4BP1/TRIM14/AICDA/NR5A2/TRIM25/STAU1/NECTIN2/TOP2A/TRIM5/TRIM22/SRPK2/TARBP2/FURIN/GSN/NOTCH1/HMGA2/TRIM68/LGALS9/CXCL8/TRIM8/PDE12/BANF1/TMEM39A/CD28/CIITA/IFITM1/PLSCR1/HMGB1/PPIA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TRIM26/CCL5/CCL5 46
GO:0071774 response to fibroblast growth factor 40/3662 105/15509 0.000615393 0.00308843 0.00185733 CPS1/CD44/CASR/NGFR/FGFR2/HYAL2/FGFR3/NDST1/FGFR1/SFRP1/PRKD2/GATA3/SHOC2/CCL2/SMOC2/WNT5A/GALNT3/KDM5B/NR4A1/RUNX2/FLRT3/ELK1/ZFP36/SPRY2/THBS1/FGF2/ZFP36L2/CXCL13/WNT4/CEP57/FRS2/CXCL8/FAM20C/GRB2/PTPN11/NOG/ZFP36L1/SPRY4/CCL5/CCL5 40
GO:0050728 negative regulation of inflammatory response 51/3662 142/15509 0.000620774 0.00311291 0.00187205 IGF1/HGF/TNFRSF1B/GRN/FOXP3/VPS35/FCGR2B/MKRN2/PTPRC/HCK/ACP5/MEFV/HAMP/GATA3/MDK/MVK/PPARD/MAPK14/IL12B/IL4/ASH1L/TNFAIP3/TEK/NR1D1/ZFP36/APOE/NDFIP1/SYT11/IL2RA/NT5E/IL10/CCN3/CYP19A1/RB1/FURIN/SOD1/DUSP10/PLK2/PSMB4/NLRX1/PRKCD/GPER1/SYK/NOD2/PTPN2/ADIPOQ/CNR2/SRC/ELANE/PTPRC/ELANE 51
GO:0010810 regulation of cell-substrate adhesion 66/3662 194/15509 0.000621727 0.00311517 0.00187341 ITGA3/EPHA3/PKP2/ATXN3/RHOA/ROCK1/CDC42/ST6GAL1/FBLN1/GSK3B/CEACAM6/ANGPT2/ABL1/PDGFB/FERMT1/OLFM4/SFRP1/SERPINE1/C1QBP/MDK/CORO1C/NEDD9/BCL6/FN1/TEK/PTK2B/CCR7/RRAS/KDR/RAC2/MEN1/CD36/CCL21/THBS1/TBCD/CCN1/PIK3R1/NOTCH1/ABI3BP/MMP14/DMTN/COL26A1/ALOX15/WNT4/DISC1/MELTF/EDIL3/EGFLAM/PTK2/PLEKHA2/LIMS1/SEMA3E/PRKCE/FGG/FGA/DAG1/FZD4/RCC2/CALR/CSF1/CIB1/NF2/SPRY4/SRC/ITGB3/PTEN 66
GO:0002461 tolerance induction dependent upon immune response 9/3662 13/15509 0.000626659 0.00312976 0.00188218 FOXP3/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 9
GO:0070317 negative regulation of G0 to G1 transition 9/3662 13/15509 0.000626659 0.00312976 0.00188218 FOXO4/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G/HLA-G 9
GO:1901668 regulation of superoxide dismutase activity 9/3662 13/15509 0.000626659 0.00312976 0.00188218 PARK7/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 9
GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis 9/3662 13/15509 0.000626659 0.00312976 0.00188218 PAK2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 9
GO:0035115 embryonic forelimb morphogenesis 16/3662 31/15509 0.000660517 0.00329061 0.00197891 HOXA11/ALX4/TP63/HOXA9/RPGRIP1L/WNT3/RECK/RUNX2/HOXD9/ALDH1A2/TFAP2A/CRABP2/SHH/ZNF358/WNT3/WNT3 16
GO:0060563 neuroepithelial cell differentiation 16/3662 31/15509 0.000660517 0.00329061 0.00197891 ABL1/SERPINE1/BCCIP/HES1/SOX4/NKX2-2/BMP2/FGF2/NOTCH1/NODAL/WNT4/CDH2/CEBPB/FAM20C/POU3F2/TUBB 16
GO:1902993 positive regulation of amyloid precursor protein catabolic process 16/3662 31/15509 0.000660517 0.00329061 0.00197891 PICALM/GSK3A/IFNG/CLU/SLC2A13/CASP3/EFNA1/RELA/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 16
GO:0001704 formation of primary germ layer 45/3662 122/15509 0.000660988 0.00329061 0.00197891 HOXA11/ITGA3/PAF1/LAMA3/FGFR2/PRKACA/ITGA8/MMP2/MMP9/BMP7/AXIN1/EYA1/GPI/BMPR1A/DKK1/WNT3/MACROH2A1/WNT5A/ITGA4/FN1/INHBA/TWSG1/COL5A1/DUSP5/ITGAV/ARMC5/EPHA2/HMGA2/ITGB1/GJA1/NODAL/MMP14/DUSP2/ITGB2/SMAD2/GRB2/SETD2/NOG/NF2/TXNRD1/ITGB3/WNT3/WNT3/GPI/PRKACA 45
GO:0051851 modulation by host of symbiont process 30/3662 73/15509 0.000674575 0.00335555 0.00201797 LTF/YTHDC2/CDC42/CCNK/SMARCB1/VAPA/HSPA8/HDAC1/TARDBP/APOE/SFTPD/HMGA2/EEF1A1/SAP30/PSMC3/CX3CR1/PAIP1/CFL1/JUN/CSF1R/PRKN/CARD9/IGF2R/ZBED1/CCL5/CCL5/CCL4/CCL4/SMARCB1/CCL4 30
GO:0032516 positive regulation of phosphoprotein phosphatase activity 13/3662 23/15509 0.000689849 0.00341508 0.00205377 PTPRC/PPP1R15A/HSP90AB1/CD33/PDGFRB/PTPA/CALM2/GNA12/PPP1R15B/CALM3/MAGI2/MTOR/PTPRC 13
GO:0034138 toll-like receptor 3 signaling pathway 13/3662 23/15509 0.000689849 0.00341508 0.00205377 WDFY1/TNFAIP3/PTPN22/TLR3/TNIP2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 13
GO:0036296 response to increased oxygen levels 13/3662 23/15509 0.000689849 0.00341508 0.00205377 NOX1/FAS/ATP6AP1/MMP2/PDGFRB/ATP6V1A/CAT/EPO/ATP6V1G1/CYP1A1/FOXO1/ATG7/TMEM199 13
GO:0060740 prostate gland epithelium morphogenesis 13/3662 23/15509 0.000689849 0.00341508 0.00205377 FGFR2/TP63/MMP2/ESR1/BMP7/SFRP1/WNT5A/NOTCH1/SHH/FRS2/CYP7B1/RARG/NOG 13
GO:0070989 oxidative demethylation 13/3662 23/15509 0.000689849 0.00341508 0.00205377 ALKBH5/CYP2D6/CYP3A5/TET1/TDG/CYP1A2/CYP3A4/TET3/CYP2D6/CYP2D6/CYP2D6/CYP2D6/CYP2D6 13
GO:2000010 positive regulation of protein localization to cell surface 13/3662 23/15509 0.000689849 0.00341508 0.00205377 TYROBP/HSP90AB1/RANGRF/TMEM35A/RIC3/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 13
GO:0055076 transition metal ion homeostasis 47/3662 129/15509 0.000695129 0.00343847 0.00206784 HFE/LTF/SLC11A1/AP3D1/HYAL2/ATP6AP1/PICALM/SLC46A1/FTL/SLC22A17/NUBP1/SLC39A14/HAMP/TFR2/HPX/SLC11A2/IFNG/RHAG/ATP6V1A/SLC30A3/EPAS1/FBXL5/NDFIP1/AP3B1/ISCU/IREB2/ATP6V1G1/SMAD4/SOD1/APP/SLC25A37/LCN2/BMP6/STEAP2/ALAS2/CYB561A3/SLC30A7/MELTF/FXN/EPB42/FTH1/ERFE/BTBD9/PRKN/TMPRSS6/TMEM199/B2M 47
GO:0003281 ventricular septum development 29/3662 70/15509 0.000704272 0.00347815 0.0020917 PRDM1/FGFR2/LRP2/HECTD1/SMAD7/NPRL3/TGFBR1/GATA3/BMPR1A/NSD2/WNT5A/HES1/SOX4/SMAD6/SMAD4/CCN1/SLIT2/NOTCH1/RBM15/TGFBR2/HEYL/NOS3/FRS2/DCTN5/RBPJ/ZFPM2/NKX2-5/NOG/SLIT3 29
GO:0006289 nucleotide-excision repair 29/3662 70/15509 0.000704272 0.00347815 0.0020917 ARID1B/NTHL1/ATXN3/ACTB/BCL7C/SMARCB1/ERCC2/POLR2I/SMARCD2/GTF2H1/BCL7A/ARID1A/RAD23B/USP45/DDB2/XPA/BRCA2/CUL4A/XPC/FANCC/ERCC3/UVSSA/BRD7/KAT5/LIG4/USP7/ARID2/SMARCB1/FAN1 29
GO:0051783 regulation of nuclear division 49/3662 136/15509 0.000723637 0.00357012 0.00214701 CDC27/IGF1/SIRT2/CDC42/NDC80/ZW10/ANAPC5/BIRC5/PDGFB/BMP7/FBXO5/CUL9/PDGFRB/WNT5A/IL1A/CDC20/TEX14/OBSL1/IL1B/PIN1/PKMYT1/LIF/CCNB1/CDCA8/APC/BORA/NUSAP1/EGF/RB1/MKI67/SPC25/WNT4/BUB1/PDE3A/ZWILCH/AURKAIP1/CD28/AURKB/CALR/PLCB1/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/PDXP 49
GO:0046685 response to arsenic-containing substance 17/3662 34/15509 0.000724047 0.00357012 0.00214701 RNF4/MKNK2/PPIF/HNRNPA1/CYP1B1/CYP1A1/ALAD/GSTO1/ATF3/TNFRSF11B/VCP/DAXX/DAXX/DAXX/DAXX/DAXX/NEFL 17
GO:0008154 actin polymerization or depolymerization 62/3662 181/15509 0.000732351 0.00360533 0.00216818 SCIN/TTC17/CYFIP2/RHOA/SPTB/WDR1/ADD2/ACTN2/ADD1/ABL1/HCK/COTL1/PYCARD/MTPN/CXCL12/CSF3/ARPC3/DBN1/WIPF1/CAPZA1/PTK2B/DSTN/CCR7/CDC42EP1/ARPC1B/WASF3/MICAL1/DBNL/CCL21/RDX/ABI2/DIAPH3/BBS4/SLIT2/ARHGAP18/GSN/CDC42EP2/PLEKHH2/DMTN/ARHGAP35/SPTBN4/ALOX15/ARPC5/CDC42EP3/SPTA1/PRKCD/RICTOR/PRKCE/CCL11/CFL1/SPTBN2/FLII/GRB2/SPTAN1/MSRB1/MTOR/IQANK1/TMSB4X/PDXP/ARPC1A/TWF2/BRK1 62
GO:0071897 DNA biosynthetic process 62/3662 181/15509 0.000732351 0.00360533 0.00216818 HGF/PARP3/SMG6/XRCC5/NOX4/MAPKAPK5/HNRNPC/HSP90AB1/PDGFB/GINS1/POLA1/JADE3/CHRAC1/PRKD2/LIG1/DNTT/SMOC2/RAD50/PDGFRB/XRN1/POLE4/PTK2B/POLM/CDKN1A/POT1/DKC1/MEN1/HNRNPA1/CCT7/CYP1B1/FGF2/PIF1/ARRB2/DTL/FAAP20/RCHY1/TERT/VCP/CCT2/TK2/RRM1/EXOSC10/DCP2/LIG4/TYMS/AURKB/MAPK15/ADIPOQ/NOP10/SRC/TFDP1/SMG5/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TEN1/TINF2 62
GO:0032495 response to muramyl dipeptide 11/3662 18/15509 0.0007373 0.00361248 0.00217248 CHMP5/NFKBIA/NOD1/MAPK14/TNFAIP3/IRF5/PTPN22/NOTCH1/NOD2/RELA/CARD9 11
GO:0032621 interleukin-18 production 11/3662 18/15509 0.0007373 0.00361248 0.00217248 IL10/GBP5/NOD2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 11
GO:0032661 regulation of interleukin-18 production 11/3662 18/15509 0.0007373 0.00361248 0.00217248 IL10/GBP5/NOD2/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 11
GO:0036344 platelet morphogenesis 11/3662 18/15509 0.0007373 0.00361248 0.00217248 WDR1/MYH9/GATA1/MPL/ZNF385A/BAP1/CASP3/C1GALT1C1/PTPN11/CIB1/PRKDC 11
GO:0051770 positive regulation of nitric-oxide synthase biosynthetic process 11/3662 18/15509 0.0007373 0.00361248 0.00217248 MAP2K4/FCER2/JAK3/CCL2/MAP2K6/IFNG/STAT1/KDR/AKAP12/TLR4/NOD2 11
GO:0051956 negative regulation of amino acid transport 11/3662 18/15509 0.0007373 0.00361248 0.00217248 ARL6IP5/SLC43A2/LEP/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 11
GO:0060389 pathway-restricted SMAD protein phosphorylation 27/3662 64/15509 0.000759888 0.00372021 0.00223727 HFE/BMP7/SMAD7/TGFB1/TGFBR1/ENG/BMPR1A/DKK1/INHBA/LRP1/BMP2/PIN1/TWSG1/GDF15/SMAD6/SMAD4/BMP6/NODAL/INHBB/TGFBR2/GDF9/NOG/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CSNK2B 27
GO:0090150 establishment of protein localization to membrane 78/3662 238/15509 0.000760987 0.00372265 0.00223874 AGK/ZDHHC6/HSPA5/SEC61A1/SEC61A2/VPS35/ATP6AP1/NSF/RAB10/BAX/BAG6/TIMM13/MICALL1/SAMM50/GZMB/TIMM9/ARFRP1/CHMP4B/UBL4A/CSK/RAB11A/SGTA/PDCD5/MAPK8/CCDC47/KRT18/ARL6/ACSL3/EMC3/PHAF1/RAB3IP/EMC4/TIMM10B/REEP2/AP3B1/ZDHHC4/NMT1/KIF13A/RDX/PREPL/SRP14/SRPRB/EGFR/PARD3/TIMM8B/ZFAND2B/DMTN/CALM3/ITGB2/ZDHHC12/EMC10/PEX19/ZDHHC3/CDK5/AMN/SRP68/MFF/ITGAM/TOMM20/HRAS/PDZK1/TOMM5/ZDHHC21/SYNE3/CDK5R1/MIEF2/CIB1/CLN3/NACA/GDI1/ZDHHC18/BAG6/FIS1/BAG6/BAG6/BAG6/BAG6/CD24 78
GO:1990000 amyloid fibril formation 18/3662 37/15509 0.000772485 0.00377592 0.00227077 FKBP1A/FUS/CRYAB/PFDN1/CLU/TARDBP/IAPP/PFDN5/USP9X/APOE/CD36/HNRNPA1/FURIN/APP/GSN/PRKN/PFDN6/B2M 18
GO:0090307 mitotic spindle assembly 26/3662 61/15509 0.000784555 0.00381549 0.00229457 RHOA/SMC1A/PIBF1/CHMP5/TPX2/BIRC5/KIF4A/MYBL2/CHMP4B/RAB11A/ARHGEF10/BCCIP/SMC3/CDC20/CHMP1A/CDCA8/KIF23/MAP9/GOLGA2/CHMP6/AURKB/CHEK2/DRG1/KIFC1/LSM14A/SPICE1 26
GO:0033211 adiponectin-activated signaling pathway 8/3662 11/15509 0.000784891 0.00381549 0.00229457 ADIPOR2/APPL1/ADIPOR1/CSNK2B/CSNK2B/CSNK2B/CSNK2B/CSNK2B 8
GO:0035709 memory T cell activation 8/3662 11/15509 0.000784891 0.00381549 0.00229457 HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A/HLA-A 8
GO:0036295 cellular response to increased oxygen levels 8/3662 11/15509 0.000784891 0.00381549 0.00229457 NOX1/FAS/ATP6AP1/ATP6V1A/ATP6V1G1/FOXO1/ATG7/TMEM199 8
GO:0060009 Sertoli cell development 8/3662 11/15509 0.000784891 0.00381549 0.00229457 ARID4B/ATRX/GATA1/IL1A/SDC1/HSD17B4/RAB13/NTRK1 8
GO:0060174 limb bud formation 8/3662 11/15509 0.000784891 0.00381549 0.00229457 FGFR2/PLXNA2/WNT3/SOX4/COL2A1/SHH/WNT3/WNT3 8
GO:2000672 negative regulation of motor neuron apoptotic process 8/3662 11/15509 0.000784891 0.00381549 0.00229457 ERBB3/MAP2K4/RHOA/ROCK1/ZPR1/CNTFR/MAP3K12/NEFL 8
GO:0022404 molting cycle process 36/3662 93/15509 0.000798958 0.00387476 0.00233021 ALX4/PUM2/CDH3/NGFR/FGFR2/TP63/GLI2/ZMPSTE24/FERMT1/ERCC2/DKK1/WNT5A/HDAC1/GORAB/INHBA/LAMA5/LRP4/NUMA1/SMAD4/LRIG1/EGFR/NOTCH1/MYSM1/FOXQ1/SHH/RBPJ/RELA/ZDHHC21/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 36
GO:0022405 hair cycle process 36/3662 93/15509 0.000798958 0.00387476 0.00233021 ALX4/PUM2/CDH3/NGFR/FGFR2/TP63/GLI2/ZMPSTE24/FERMT1/ERCC2/DKK1/WNT5A/HDAC1/GORAB/INHBA/LAMA5/LRP4/NUMA1/SMAD4/LRIG1/EGFR/NOTCH1/MYSM1/FOXQ1/SHH/RBPJ/RELA/ZDHHC21/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 36
GO:0098773 skin epidermis development 36/3662 93/15509 0.000798958 0.00387476 0.00233021 ALX4/PUM2/CDH3/NGFR/FGFR2/TP63/GLI2/ZMPSTE24/FERMT1/ERCC2/DKK1/WNT5A/HDAC1/GORAB/INHBA/LAMA5/AP3B1/LRP4/NUMA1/SMAD4/EGFR/NOTCH1/MYSM1/FOXQ1/SHH/RBPJ/RELA/ZDHHC21/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 36
GO:1990266 neutrophil migration 45/3662 123/15509 0.000807323 0.00391226 0.00235277 CD74/WDR1/DNM1L/CCL22/CCL17/PIK3CG/C1QBP/CCL2/MDK/IL1A/CCL20/CSF3R/IL1B/CCR7/RAC2/CCL21/SLIT2/CXCL13/ITGB2/CXCR1/PF4/SYK/NOD2/RHOH/CXCL8/CCL11/BSG/CCL19/CXCR2/PDE4B/PPIA/FUT4/PRTN3/DPP4/CD177/PECAM1/CCL5/CCL5/CCL4/CCL18/CCL4/PRTN3/CCL4/CCL18/CCL18 45
GO:0033688 regulation of osteoblast proliferation 14/3662 26/15509 0.000828286 0.00400446 0.00240821 LTF/EIF2AK2/FGFR2/RHOA/ABL1/GATA1/SFRP1/BMP2/ITGAV/IGF1R/CCN1/MN1/NF2/ITGB3 14
GO:0051000 positive regulation of nitric-oxide synthase activity 14/3662 26/15509 0.000828286 0.00400446 0.00240821 FCER2/NOD1/PTK2B/APOE/CALM3/TERT/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 14
GO:0090200 positive regulation of release of cytochrome c from mitochondria 14/3662 26/15509 0.000828286 0.00400446 0.00240821 BAD/BAK1/BAX/DNM1L/MMP9/PYCARD/PDCD5/PPIF/TNFSF10/HRK/PMAIP1/BCL2L11/GPER1/MFF 14
GO:0030042 actin filament depolymerization 23/3662 52/15509 0.000835901 0.0040287 0.00242279 SCIN/SPTB/WDR1/ADD2/ACTN2/ADD1/MTPN/CAPZA1/DSTN/MICAL1/RDX/GSN/PLEKHH2/DMTN/SPTBN4/SPTA1/CFL1/SPTBN2/FLII/SPTAN1/IQANK1/PDXP/TWF2 23
GO:0032387 negative regulation of intracellular transport 23/3662 52/15509 0.000835901 0.0040287 0.00242279 SP100/VPS35/DERL2/LMAN1/SIRT6/RANGAP1/FERMT1/CRYAB/PARK7/NUP153/CD36/MDFIC/SNX12/BAG3/DMTN/ARFIP1/CDK5/PKIG/YOD1/ADIPOQ/SVIP/UBE2J1/GDI1 23
GO:0043457 regulation of cellular respiration 23/3662 52/15509 0.000835901 0.0040287 0.00242279 RHOA/PPIF/IFNG/IL4/PARK7/SLC25A23/TRAP1/CBFA2T3/ISCU/AK4/VCP/PRELID1/SLC25A33/PDE12/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF/IL10RB 23
GO:0043903 regulation of biological process involved in symbiotic interaction 23/3662 52/15509 0.000835901 0.0040287 0.00242279 CD4/LTF/CD74/MID2/TRIM14/ARG1/TRIM25/NECTIN2/TRIM5/TRIM22/SFTPD/ITGAV/FURIN/GSN/TRIM68/LGALS9/CXCL8/TRIM8/CIITA/EXOC7/IFITM1/HMGB1/TRIM26 23
GO:0001942 hair follicle development 35/3662 90/15509 0.000850785 0.00409407 0.0024621 ALX4/PUM2/CDH3/NGFR/FGFR2/TP63/GLI2/ZMPSTE24/FERMT1/ERCC2/DKK1/WNT5A/HDAC1/GORAB/INHBA/LAMA5/LRP4/NUMA1/SMAD4/EGFR/NOTCH1/MYSM1/FOXQ1/SHH/RBPJ/RELA/ZDHHC21/TNF/TNF/TNF/TNF/TNF/TNF/TNF/TNF 35
GO:0031058 positive regulation of histone modification 35/3662 90/15509 0.000850785